Motif ID: Erg

Z-value: 0.967


Transcription factors associated with Erg:

Gene SymbolEntrez IDGene Name
Erg ENSMUSG00000040732.12 Erg

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Ergmm10_v2_chr16_-_95459245_954593840.633.5e-05Click!


Activity profile for motif Erg.

activity profile for motif Erg


Sorted Z-values histogram for motif Erg

Sorted Z-values for motif Erg



Network of associatons between targets according to the STRING database.



First level regulatory network of Erg

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr4_+_144892813 6.579 ENSMUST00000105744.1
ENSMUST00000171001.1
Dhrs3

dehydrogenase/reductase (SDR family) member 3

chr1_-_56969864 5.726 ENSMUST00000177424.1
Satb2
special AT-rich sequence binding protein 2
chr1_-_56972437 5.515 ENSMUST00000042857.7
Satb2
special AT-rich sequence binding protein 2
chr1_-_56969827 4.994 ENSMUST00000176759.1
Satb2
special AT-rich sequence binding protein 2
chr4_+_144893077 4.842 ENSMUST00000154208.1
Dhrs3
dehydrogenase/reductase (SDR family) member 3
chr12_+_75308308 4.367 ENSMUST00000118602.1
ENSMUST00000118966.1
ENSMUST00000055390.5
Rhoj


ras homolog gene family, member J


chr4_+_144893127 4.071 ENSMUST00000142808.1
Dhrs3
dehydrogenase/reductase (SDR family) member 3
chr2_+_32646586 3.695 ENSMUST00000009705.7
ENSMUST00000167841.1
Eng

endoglin

chr11_-_55419898 3.480 ENSMUST00000108858.1
ENSMUST00000141530.1
Sparc

secreted acidic cysteine rich glycoprotein

chr8_+_70501116 3.426 ENSMUST00000127983.1
Crlf1
cytokine receptor-like factor 1
chr11_-_101785252 3.385 ENSMUST00000164750.1
ENSMUST00000107176.1
ENSMUST00000017868.6
Etv4


ets variant gene 4 (E1A enhancer binding protein, E1AF)


chr7_-_27181149 3.355 ENSMUST00000071986.6
ENSMUST00000121848.1
Mia

melanoma inhibitory activity

chr13_-_41487306 3.277 ENSMUST00000021794.6
Nedd9
neural precursor cell expressed, developmentally down-regulated gene 9
chr7_+_30413744 3.236 ENSMUST00000032800.9
Tyrobp
TYRO protein tyrosine kinase binding protein
chr17_-_68004075 3.228 ENSMUST00000024840.5
Arhgap28
Rho GTPase activating protein 28
chr16_+_43363855 3.123 ENSMUST00000156367.1
Zbtb20
zinc finger and BTB domain containing 20
chr13_-_37050237 3.011 ENSMUST00000164727.1
F13a1
coagulation factor XIII, A1 subunit
chr3_+_68869563 2.976 ENSMUST00000054551.2
1110032F04Rik
RIKEN cDNA 1110032F04 gene
chr3_-_146781351 2.803 ENSMUST00000005164.7
Prkacb
protein kinase, cAMP dependent, catalytic, beta
chr3_+_95526777 2.757 ENSMUST00000015667.2
ENSMUST00000116304.2
Ctss

cathepsin S

chr9_-_29411736 2.689 ENSMUST00000115236.1
Ntm
neurotrimin
chr9_+_20868628 2.623 ENSMUST00000043911.7
A230050P20Rik
RIKEN cDNA A230050P20 gene
chr11_-_69695802 2.576 ENSMUST00000108649.1
ENSMUST00000174159.1
ENSMUST00000181810.1
BC096441

Tnfsf12
cDNA sequence BC096441

tumor necrosis factor (ligand) superfamily, member 12
chr11_-_106715251 2.528 ENSMUST00000080853.4
ENSMUST00000183610.1
ENSMUST00000103069.3
ENSMUST00000106796.2
Pecam1



platelet/endothelial cell adhesion molecule 1



chr5_+_75152274 2.528 ENSMUST00000000476.8
Pdgfra
platelet derived growth factor receptor, alpha polypeptide
chr17_+_86167777 2.513 ENSMUST00000097275.2
Prkce
protein kinase C, epsilon
chr14_-_25769033 2.403 ENSMUST00000069180.7
Zcchc24
zinc finger, CCHC domain containing 24
chr17_+_3397189 2.349 ENSMUST00000072156.6
Tiam2
T cell lymphoma invasion and metastasis 2
chr1_+_16688405 2.338 ENSMUST00000026881.4
Ly96
lymphocyte antigen 96
chr16_-_95459245 2.311 ENSMUST00000176345.1
ENSMUST00000121809.2
ENSMUST00000118113.1
ENSMUST00000122199.1
Erg



avian erythroblastosis virus E-26 (v-ets) oncogene related



chr16_+_43364145 2.306 ENSMUST00000148775.1
Zbtb20
zinc finger and BTB domain containing 20
chr5_+_111733924 2.279 ENSMUST00000180627.1
Gm26897
predicted gene, 26897
chr10_+_79988584 2.224 ENSMUST00000004784.4
ENSMUST00000105374.1
Cnn2

calponin 2

chr6_+_4003926 2.217 ENSMUST00000031670.8
Gng11
guanine nucleotide binding protein (G protein), gamma 11
chr16_-_38713235 2.173 ENSMUST00000023487.4
Arhgap31
Rho GTPase activating protein 31
chr9_-_54661870 2.034 ENSMUST00000034822.5
Acsbg1
acyl-CoA synthetase bubblegum family member 1
chr16_+_17797282 2.009 ENSMUST00000012161.3
Scarf2
scavenger receptor class F, member 2
chr9_-_120068263 1.987 ENSMUST00000064165.3
ENSMUST00000177637.1
Cx3cr1

chemokine (C-X3-C) receptor 1

chr2_-_148443543 1.976 ENSMUST00000099269.3
Cd93
CD93 antigen
chr19_+_6401675 1.953 ENSMUST00000113471.1
ENSMUST00000113469.2
Rasgrp2

RAS, guanyl releasing protein 2

chr8_+_128359065 1.946 ENSMUST00000026917.8
Nrp1
neuropilin 1
chr7_-_31042078 1.896 ENSMUST00000162116.1
ENSMUST00000159924.1
ENSMUST00000159753.1
ENSMUST00000160689.1
ENSMUST00000162733.1
ENSMUST00000162087.1
ENSMUST00000009831.7
Fxyd5






FXYD domain-containing ion transport regulator 5






chr3_-_82074639 1.866 ENSMUST00000029635.8
Gucy1b3
guanylate cyclase 1, soluble, beta 3
chr8_+_104101625 1.848 ENSMUST00000034339.8
Cdh5
cadherin 5
chr1_+_177444653 1.830 ENSMUST00000094276.3
Zbtb18
zinc finger and BTB domain containing 18
chr14_-_31168587 1.825 ENSMUST00000036618.7
Stab1
stabilin 1
chr10_-_68278713 1.775 ENSMUST00000020106.7
Arid5b
AT rich interactive domain 5B (MRF1-like)
chr9_-_29412204 1.761 ENSMUST00000115237.1
Ntm
neurotrimin
chr18_+_37473538 1.722 ENSMUST00000050034.1
Pcdhb15
protocadherin beta 15
chr16_+_36934976 1.713 ENSMUST00000023531.8
Hcls1
hematopoietic cell specific Lyn substrate 1
chr11_+_61653259 1.685 ENSMUST00000004959.2
Grap
GRB2-related adaptor protein
chr3_-_87768932 1.620 ENSMUST00000173184.1
ENSMUST00000172621.1
ENSMUST00000174759.1
ENSMUST00000172590.1
ENSMUST00000079083.5
Pear1




platelet endothelial aggregation receptor 1




chr11_+_115163333 1.615 ENSMUST00000021077.3
Slc9a3r1
solute carrier family 9 (sodium/hydrogen exchanger), member 3 regulator 1
chr5_-_148392810 1.608 ENSMUST00000138257.1
Slc7a1
solute carrier family 7 (cationic amino acid transporter, y+ system), member 1
chr3_+_137341103 1.569 ENSMUST00000119475.1
Emcn
endomucin
chr4_-_118490030 1.538 ENSMUST00000047421.5
Tie1
tyrosine kinase with immunoglobulin-like and EGF-like domains 1
chr3_+_26331150 1.518 ENSMUST00000099182.2
A830092H15Rik
RIKEN cDNA A830092H15 gene
chr1_+_75507077 1.506 ENSMUST00000037330.4
Inha
inhibin alpha
chr5_-_147725988 1.502 ENSMUST00000110529.1
ENSMUST00000031652.3
ENSMUST00000031653.5
Flt1


FMS-like tyrosine kinase 1


chr11_-_48816936 1.482 ENSMUST00000140800.1
Trim41
tripartite motif-containing 41
chr14_+_70554056 1.472 ENSMUST00000022691.7
Hr
hairless
chr11_-_52282564 1.463 ENSMUST00000086844.3
Tcf7
transcription factor 7, T cell specific
chr17_+_43389436 1.422 ENSMUST00000113599.1
Gpr116
G protein-coupled receptor 116
chr4_-_118489755 1.401 ENSMUST00000184261.1
Tie1
tyrosine kinase with immunoglobulin-like and EGF-like domains 1
chr14_+_70553687 1.397 ENSMUST00000161069.1
Hr
hairless
chr7_-_130266237 1.390 ENSMUST00000117872.1
ENSMUST00000120187.1
Fgfr2

fibroblast growth factor receptor 2

chr13_+_109903089 1.386 ENSMUST00000120664.1
Pde4d
phosphodiesterase 4D, cAMP specific
chr11_-_120041774 1.371 ENSMUST00000103019.1
Aatk
apoptosis-associated tyrosine kinase
chr18_+_37294840 1.364 ENSMUST00000056522.3
Pcdhb2
protocadherin beta 2
chr18_-_35215008 1.356 ENSMUST00000091636.3
Lrrtm2
leucine rich repeat transmembrane neuronal 2
chr16_-_4880284 1.355 ENSMUST00000037843.6
Ubald1
UBA-like domain containing 1
chr15_-_37458523 1.345 ENSMUST00000116445.2
Ncald
neurocalcin delta
chr13_+_109632760 1.341 ENSMUST00000135275.1
Pde4d
phosphodiesterase 4D, cAMP specific
chr1_+_165788681 1.328 ENSMUST00000161971.1
ENSMUST00000178336.1
ENSMUST00000005907.5
ENSMUST00000027849.4
Cd247



CD247 antigen



chr19_+_27217011 1.320 ENSMUST00000164746.1
ENSMUST00000172302.1
Vldlr

very low density lipoprotein receptor

chr10_+_21993890 1.307 ENSMUST00000092673.4
Sgk1
serum/glucocorticoid regulated kinase 1
chr18_+_40258361 1.292 ENSMUST00000091927.4
Kctd16
potassium channel tetramerisation domain containing 16
chr3_+_68494208 1.288 ENSMUST00000182719.1
Schip1
schwannomin interacting protein 1
chr1_-_134235420 1.272 ENSMUST00000038191.6
ENSMUST00000086465.4
Adora1

adenosine A1 receptor

chr11_+_90030295 1.252 ENSMUST00000092788.3
Tmem100
transmembrane protein 100
chr15_+_27466647 1.242 ENSMUST00000022875.6
Ank
progressive ankylosis
chr3_+_137341067 1.230 ENSMUST00000122064.1
Emcn
endomucin
chr4_+_126148457 1.226 ENSMUST00000106150.2
Eva1b
eva-1 homolog B (C. elegans)
chr11_-_83302586 1.191 ENSMUST00000176374.1
Pex12
peroxisomal biogenesis factor 12
chr1_+_165788746 1.190 ENSMUST00000161559.2
Cd247
CD247 antigen
chr2_+_4718145 1.168 ENSMUST00000056914.6
Bend7
BEN domain containing 7
chr7_-_90129339 1.166 ENSMUST00000181189.1
2310010J17Rik
RIKEN cDNA 2310010J17 gene
chr7_-_128298081 1.164 ENSMUST00000033044.9
BC017158
cDNA sequence BC017158
chr11_+_70647258 1.161 ENSMUST00000037534.7
Rnf167
ring finger protein 167
chr1_+_132008285 1.159 ENSMUST00000146432.1
Elk4
ELK4, member of ETS oncogene family
chr17_-_25081138 1.158 ENSMUST00000024984.6
Tmem204
transmembrane protein 204
chr7_+_141461728 1.156 ENSMUST00000167491.1
ENSMUST00000165194.1
Efcab4a

EF-hand calcium binding domain 4A

chr19_+_47854970 1.151 ENSMUST00000026050.7
Gsto1
glutathione S-transferase omega 1
chr14_-_70207637 1.133 ENSMUST00000022682.5
Sorbs3
sorbin and SH3 domain containing 3
chrX_+_159840463 1.133 ENSMUST00000112451.1
ENSMUST00000112453.2
Sh3kbp1

SH3-domain kinase binding protein 1

chr12_-_34528844 1.120 ENSMUST00000110819.2
Hdac9
histone deacetylase 9
chr13_+_40886758 1.119 ENSMUST00000069958.7
Gcnt2
glucosaminyl (N-acetyl) transferase 2, I-branching enzyme
chr1_-_162478004 1.114 ENSMUST00000086074.5
ENSMUST00000070330.7
Dnm3

dynamin 3

chr2_-_93046053 1.109 ENSMUST00000111272.1
ENSMUST00000178666.1
ENSMUST00000147339.1
Prdm11


PR domain containing 11


chr11_-_69696058 1.098 ENSMUST00000094070.4
ENSMUST00000180587.1
BC096441
Tnfsf12
cDNA sequence BC096441
tumor necrosis factor (ligand) superfamily, member 12
chr4_-_127313980 1.091 ENSMUST00000053753.7
Gja4
gap junction protein, alpha 4
chr6_+_65778988 1.087 ENSMUST00000031976.7
ENSMUST00000081219.7
ENSMUST00000031973.6
ENSMUST00000172638.1
Prdm5



PR domain containing 5



chr2_-_7395879 1.072 ENSMUST00000182404.1
Celf2
CUGBP, Elav-like family member 2
chr17_-_14694223 1.057 ENSMUST00000170872.1
Thbs2
thrombospondin 2
chr5_-_44799643 1.053 ENSMUST00000070748.5
Ldb2
LIM domain binding 2
chr12_-_58269162 1.040 ENSMUST00000062254.2
Clec14a
C-type lectin domain family 14, member a
chr19_+_27217357 1.039 ENSMUST00000047645.6
ENSMUST00000167487.1
Vldlr

very low density lipoprotein receptor

chr10_-_58675631 1.024 ENSMUST00000003312.4
Edar
ectodysplasin-A receptor
chr1_-_154725920 1.019 ENSMUST00000004214.8
Cacna1e
calcium channel, voltage-dependent, R type, alpha 1E subunit
chr2_-_167492826 1.010 ENSMUST00000109211.2
ENSMUST00000057627.9
Spata2

spermatogenesis associated 2

chr19_-_6992478 0.999 ENSMUST00000025915.5
Dnajc4
DnaJ (Hsp40) homolog, subfamily C, member 4
chr5_+_117133567 0.992 ENSMUST00000179276.1
ENSMUST00000092889.5
ENSMUST00000145640.1
Taok3


TAO kinase 3


chr10_-_83648713 0.991 ENSMUST00000020500.7
Appl2
adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 2
chr4_+_133039482 0.988 ENSMUST00000105914.1
Ahdc1
AT hook, DNA binding motif, containing 1
chr11_+_75650501 0.970 ENSMUST00000102505.3
Myo1c
myosin IC
chrX_+_6577259 0.967 ENSMUST00000089520.2
Shroom4
shroom family member 4
chr5_-_121836852 0.947 ENSMUST00000086310.1
Sh2b3
SH2B adaptor protein 3
chr5_-_121836810 0.919 ENSMUST00000118580.1
ENSMUST00000040308.7
Sh2b3

SH2B adaptor protein 3

chr11_+_83302641 0.906 ENSMUST00000176430.1
ENSMUST00000065692.7
Ap2b1

adaptor-related protein complex 2, beta 1 subunit

chr3_-_122984404 0.905 ENSMUST00000090379.2
Usp53
ubiquitin specific peptidase 53
chr6_-_142702259 0.900 ENSMUST00000073173.5
ENSMUST00000111771.1
ENSMUST00000087527.4
ENSMUST00000100827.2
Abcc9



ATP-binding cassette, sub-family C (CFTR/MRP), member 9



chr16_-_44016387 0.898 ENSMUST00000036174.3
Gramd1c
GRAM domain containing 1C
chr5_-_113650390 0.898 ENSMUST00000047936.6
Cmklr1
chemokine-like receptor 1
chr8_+_69808672 0.892 ENSMUST00000036074.8
ENSMUST00000123453.1
Gmip

Gem-interacting protein

chr11_+_83302817 0.863 ENSMUST00000142680.1
Ap2b1
adaptor-related protein complex 2, beta 1 subunit
chr3_-_141982224 0.863 ENSMUST00000029948.8
Bmpr1b
bone morphogenetic protein receptor, type 1B
chr11_-_69695521 0.862 ENSMUST00000181261.1
Tnfsf12
tumor necrosis factor (ligand) superfamily, member 12
chr13_-_92030897 0.859 ENSMUST00000149630.1
Rasgrf2
RAS protein-specific guanine nucleotide-releasing factor 2
chr2_+_163602331 0.847 ENSMUST00000152135.1
Ttpal
tocopherol (alpha) transfer protein-like
chr11_-_75454656 0.842 ENSMUST00000173320.1
Wdr81
WD repeat domain 81
chr10_-_78591945 0.841 ENSMUST00000040580.6
Syde1
synapse defective 1, Rho GTPase, homolog 1 (C. elegans)
chrX_+_110814390 0.841 ENSMUST00000078229.3
Pou3f4
POU domain, class 3, transcription factor 4
chr10_+_39612934 0.841 ENSMUST00000019987.6
Traf3ip2
TRAF3 interacting protein 2
chr6_-_122340200 0.835 ENSMUST00000159384.1
Phc1
polyhomeotic-like 1 (Drosophila)
chr2_-_5714490 0.832 ENSMUST00000044009.7
Camk1d
calcium/calmodulin-dependent protein kinase ID
chr13_+_109260481 0.826 ENSMUST00000153234.1
Pde4d
phosphodiesterase 4D, cAMP specific
chr6_-_124738579 0.824 ENSMUST00000174265.1
ENSMUST00000004377.8
Ptpn6

protein tyrosine phosphatase, non-receptor type 6

chr1_-_87394721 0.823 ENSMUST00000113212.3
Kcnj13
potassium inwardly-rectifying channel, subfamily J, member 13
chr8_+_94037198 0.813 ENSMUST00000109556.2
ENSMUST00000093301.2
ENSMUST00000060632.7
Ogfod1


2-oxoglutarate and iron-dependent oxygenase domain containing 1


chr3_+_116008220 0.809 ENSMUST00000106502.1
Extl2
exostoses (multiple)-like 2
chr14_-_45529964 0.808 ENSMUST00000150660.1
Fermt2
fermitin family homolog 2 (Drosophila)
chr17_-_56133817 0.790 ENSMUST00000167545.1
Sema6b
sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6B
chrX_+_159627534 0.786 ENSMUST00000073094.3
Sh3kbp1
SH3-domain kinase binding protein 1
chr15_+_102102926 0.784 ENSMUST00000169627.1
ENSMUST00000046144.9
Tenc1

tensin like C1 domain-containing phosphatase

chr7_+_87602544 0.775 ENSMUST00000167164.1
ENSMUST00000107263.2
Grm5

glutamate receptor, metabotropic 5

chr11_+_32533290 0.771 ENSMUST00000102821.3
Stk10
serine/threonine kinase 10
chrX_+_7722267 0.767 ENSMUST00000125991.1
ENSMUST00000148624.1
Wdr45

WD repeat domain 45

chr1_-_133921393 0.766 ENSMUST00000048432.5
Prelp
proline arginine-rich end leucine-rich repeat
chr7_+_101378183 0.766 ENSMUST00000084895.5
Arap1
ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1
chr10_-_39899238 0.761 ENSMUST00000178563.1
AA474331
expressed sequence AA474331
chrX_+_162760388 0.757 ENSMUST00000033720.5
ENSMUST00000112327.1
Rbbp7

retinoblastoma binding protein 7

chr1_-_52817503 0.757 ENSMUST00000162576.1
Inpp1
inositol polyphosphate-1-phosphatase
chr8_+_22476700 0.752 ENSMUST00000067786.7
Slc20a2
solute carrier family 20, member 2
chr11_-_118401826 0.744 ENSMUST00000106290.3
ENSMUST00000043722.3
Lgals3bp

lectin, galactoside-binding, soluble, 3 binding protein

chr18_+_5593566 0.742 ENSMUST00000160910.1
Zeb1
zinc finger E-box binding homeobox 1
chr10_-_83648631 0.741 ENSMUST00000146876.2
ENSMUST00000176294.1
Appl2

adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 2

chr2_+_4717825 0.741 ENSMUST00000184139.1
ENSMUST00000115022.1
Bend7

BEN domain containing 7

chr10_-_62507737 0.736 ENSMUST00000020271.6
Srgn
serglycin
chr1_+_58802492 0.736 ENSMUST00000165549.1
Casp8
caspase 8
chrX_+_7722214 0.730 ENSMUST00000043045.2
ENSMUST00000116634.1
ENSMUST00000115689.3
ENSMUST00000131077.1
ENSMUST00000115688.1
ENSMUST00000116633.1
Wdr45





WD repeat domain 45





chr5_-_143180721 0.726 ENSMUST00000164068.1
ENSMUST00000049861.4
ENSMUST00000165318.1
Rbak


RB-associated KRAB repressor


chr1_-_155527083 0.726 ENSMUST00000097531.2
Gm5532
predicted gene 5532
chr13_-_115101909 0.713 ENSMUST00000061673.7
Itga1
integrin alpha 1
chr7_-_79743034 0.713 ENSMUST00000032761.7
Pex11a
peroxisomal biogenesis factor 11 alpha
chr2_+_91096744 0.711 ENSMUST00000132741.2
Spi1
spleen focus forming virus (SFFV) proviral integration oncogene
chr2_+_91202885 0.708 ENSMUST00000150403.1
ENSMUST00000002172.7
ENSMUST00000155418.1
Acp2


acid phosphatase 2, lysosomal


chr6_-_87811771 0.704 ENSMUST00000078647.4
ENSMUST00000032135.5
Rab43

RAB43, member RAS oncogene family

chr6_-_125313844 0.700 ENSMUST00000032489.7
Ltbr
lymphotoxin B receptor
chr12_+_76533540 0.699 ENSMUST00000075249.4
Plekhg3
pleckstrin homology domain containing, family G (with RhoGef domain) member 3
chr9_-_20952838 0.688 ENSMUST00000004202.9
Dnmt1
DNA methyltransferase (cytosine-5) 1
chr7_-_27553138 0.680 ENSMUST00000127240.1
ENSMUST00000117095.1
ENSMUST00000117611.1
Pld3


phospholipase D family, member 3


chr12_-_55821157 0.679 ENSMUST00000110687.1
ENSMUST00000085385.5
Ralgapa1

Ral GTPase activating protein, alpha subunit 1

chr7_+_27553244 0.674 ENSMUST00000067386.7
2310022A10Rik
RIKEN cDNA 2310022A10 gene
chr18_+_24470844 0.662 ENSMUST00000097646.3
2700062C07Rik
RIKEN cDNA 2700062C07 gene
chr17_+_33638056 0.660 ENSMUST00000052079.7
Pram1
PML-RAR alpha-regulated adaptor molecule 1
chr10_-_78352469 0.656 ENSMUST00000138035.1
Agpat3
1-acylglycerol-3-phosphate O-acyltransferase 3
chr13_+_119623819 0.654 ENSMUST00000099241.2
Ccl28
chemokine (C-C motif) ligand 28
chr19_+_6341121 0.653 ENSMUST00000025897.6
ENSMUST00000130382.1
Map4k2

mitogen-activated protein kinase kinase kinase kinase 2

chr14_+_55591708 0.653 ENSMUST00000019443.8
Rnf31
ring finger protein 31
chr9_-_110476637 0.641 ENSMUST00000111934.1
ENSMUST00000068025.6
Klhl18

kelch-like 18

chr1_-_52817643 0.637 ENSMUST00000027271.2
Inpp1
inositol polyphosphate-1-phosphatase
chrX_+_162760427 0.635 ENSMUST00000112326.1
Rbbp7
retinoblastoma binding protein 7
chr6_-_54992946 0.627 ENSMUST00000131475.1
Ggct
gamma-glutamyl cyclotransferase
chr10_+_115384951 0.626 ENSMUST00000036044.8
Zfc3h1
zinc finger, C3H1-type containing
chr4_+_118620799 0.623 ENSMUST00000030501.8
Ebna1bp2
EBNA1 binding protein 2
chr2_+_165055625 0.621 ENSMUST00000017799.5
ENSMUST00000073707.2
Cd40

CD40 antigen

chr13_+_40859768 0.621 ENSMUST00000110191.2
Gcnt2
glucosaminyl (N-acetyl) transferase 2, I-branching enzyme
chr1_+_152807877 0.617 ENSMUST00000027754.6
Ncf2
neutrophil cytosolic factor 2
chr6_-_122339627 0.617 ENSMUST00000161210.1
ENSMUST00000161054.1
ENSMUST00000159252.1
ENSMUST00000161739.1
ENSMUST00000161149.1
Phc1




polyhomeotic-like 1 (Drosophila)




chr9_+_21526144 0.609 ENSMUST00000086361.5
ENSMUST00000179459.1
ENSMUST00000173769.2
AB124611


cDNA sequence AB124611


chr18_-_35740499 0.605 ENSMUST00000115728.3
Tmem173
transmembrane protein 173
chr11_+_116434087 0.604 ENSMUST00000057676.6
Ubald2
UBA-like domain containing 2
chr6_-_48708206 0.603 ENSMUST00000119315.1
ENSMUST00000053661.4
Gimap6

GTPase, IMAP family member 6

chr10_+_90576252 0.602 ENSMUST00000182427.1
ENSMUST00000182053.1
ENSMUST00000182113.1
Anks1b


ankyrin repeat and sterile alpha motif domain containing 1B


chr15_-_89170688 0.602 ENSMUST00000060808.9
Plxnb2
plexin B2
chr18_-_3281036 0.600 ENSMUST00000049942.6
ENSMUST00000139537.1
ENSMUST00000124747.1
Crem


cAMP responsive element modulator


chr5_+_105732063 0.598 ENSMUST00000154807.1
Lrrc8d
leucine rich repeat containing 8D
chr11_-_79530569 0.596 ENSMUST00000103236.3
ENSMUST00000170799.1
ENSMUST00000170422.2
Evi2a

Evi2b
ecotropic viral integration site 2a

ecotropic viral integration site 2b
chr1_-_4496400 0.596 ENSMUST00000027035.3
Sox17
SRY-box containing gene 17
chr5_+_99979061 0.593 ENSMUST00000046721.1
4930524J08Rik
RIKEN cDNA 4930524J08 gene

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
1.4 15.5 GO:0042572 retinol metabolic process(GO:0042572)
1.2 3.7 GO:1905072 detection of oxygen(GO:0003032) cardiac jelly development(GO:1905072)
1.0 16.2 GO:0021902 commitment of neuronal cell to specific neuron type in forebrain(GO:0021902)
1.0 3.0 GO:0072378 blood coagulation, fibrin clot formation(GO:0072378)
0.9 4.5 GO:0061438 renal system vasculature morphogenesis(GO:0061438) kidney vasculature morphogenesis(GO:0061439)
0.8 3.2 GO:1904425 negative regulation of GTP binding(GO:1904425)
0.6 7.7 GO:0002281 macrophage activation involved in immune response(GO:0002281)
0.6 2.5 GO:0050904 diapedesis(GO:0050904)
0.6 1.9 GO:0099548 trans-synaptic signaling by nitric oxide(GO:0099548)
0.6 2.9 GO:0003199 endocardial cushion to mesenchymal transition involved in heart valve formation(GO:0003199)
0.5 3.3 GO:0033600 negative regulation of mammary gland epithelial cell proliferation(GO:0033600)
0.5 1.6 GO:0042939 glutathione transport(GO:0034635) tripeptide transport(GO:0042939)
0.5 3.2 GO:2000672 negative regulation of motor neuron apoptotic process(GO:2000672)
0.5 2.4 GO:0034436 glycoprotein transport(GO:0034436)
0.5 2.3 GO:0032497 detection of lipopolysaccharide(GO:0032497)
0.5 1.4 GO:0035604 fibroblast growth factor receptor signaling pathway involved in negative regulation of apoptotic process in bone marrow(GO:0035602) fibroblast growth factor receptor signaling pathway involved in hemopoiesis(GO:0035603) fibroblast growth factor receptor signaling pathway involved in positive regulation of cell proliferation in bone marrow(GO:0035604) coronal suture morphogenesis(GO:0060365) squamous basal epithelial stem cell differentiation involved in prostate gland acinus development(GO:0060529)
0.4 1.3 GO:0032241 positive regulation of nucleobase-containing compound transport(GO:0032241) regulation of nucleoside transport(GO:0032242) negative regulation of circadian sleep/wake cycle, non-REM sleep(GO:0042323) negative regulation of mucus secretion(GO:0070256)
0.4 4.4 GO:0061299 retina vasculature morphogenesis in camera-type eye(GO:0061299)
0.4 1.6 GO:0061010 gall bladder development(GO:0061010)
0.4 1.2 GO:0071544 diphosphoinositol polyphosphate catabolic process(GO:0071544)
0.4 1.5 GO:0002681 somatic diversification of T cell receptor genes(GO:0002568) somatic recombination of T cell receptor gene segments(GO:0002681) T cell receptor V(D)J recombination(GO:0033153)
0.3 2.9 GO:0099590 neurotransmitter receptor internalization(GO:0099590)
0.3 1.7 GO:0036438 maintenance of lens transparency(GO:0036438)
0.3 1.2 GO:0060316 positive regulation of ryanodine-sensitive calcium-release channel activity(GO:0060316)
0.3 1.1 GO:0043654 recognition of apoptotic cell(GO:0043654)
0.3 0.8 GO:0050859 negative regulation of B cell receptor signaling pathway(GO:0050859)
0.3 3.6 GO:1901898 regulation of cell communication by electrical coupling involved in cardiac conduction(GO:1901844) negative regulation of relaxation of cardiac muscle(GO:1901898)
0.3 1.8 GO:0001955 blood vessel maturation(GO:0001955)
0.3 0.8 GO:1902938 regulation of intracellular calcium activated chloride channel activity(GO:1902938)
0.3 2.8 GO:1901621 negative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning(GO:1901621)
0.3 1.5 GO:0046880 regulation of follicle-stimulating hormone secretion(GO:0046880) follicle-stimulating hormone secretion(GO:0046884)
0.3 1.5 GO:0048597 post-embryonic camera-type eye morphogenesis(GO:0048597)
0.2 0.7 GO:0033364 mast cell secretory granule organization(GO:0033364)
0.2 1.7 GO:0030854 positive regulation of granulocyte differentiation(GO:0030854)
0.2 0.7 GO:0035526 retrograde transport, plasma membrane to Golgi(GO:0035526)
0.2 2.1 GO:0060613 fat pad development(GO:0060613)
0.2 0.9 GO:0001550 ovarian cumulus expansion(GO:0001550) fused antrum stage(GO:0048165)
0.2 1.3 GO:0060842 arterial endothelial cell differentiation(GO:0060842)
0.2 1.2 GO:0035435 phosphate ion transmembrane transport(GO:0035435)
0.2 1.0 GO:0090273 regulation of somatostatin secretion(GO:0090273)
0.2 0.8 GO:0019276 UDP-N-acetylgalactosamine metabolic process(GO:0019276)
0.2 1.0 GO:1900748 positive regulation of vascular endothelial growth factor signaling pathway(GO:1900748)
0.2 0.6 GO:0002946 tRNA C5-cytosine methylation(GO:0002946)
0.2 0.6 GO:0048294 negative regulation of isotype switching to IgE isotypes(GO:0048294)
0.2 0.6 GO:0010936 negative regulation of macrophage cytokine production(GO:0010936)
0.2 3.0 GO:0030574 collagen catabolic process(GO:0030574)
0.2 0.5 GO:0070944 neutrophil mediated killing of bacterium(GO:0070944)
0.2 0.7 GO:1902262 apoptotic process involved in patterning of blood vessels(GO:1902262)
0.2 0.7 GO:0090309 positive regulation of methylation-dependent chromatin silencing(GO:0090309)
0.2 0.3 GO:0090187 positive regulation of pancreatic juice secretion(GO:0090187)
0.2 0.8 GO:1901165 positive regulation of trophoblast cell migration(GO:1901165)
0.2 0.7 GO:1903237 negative regulation of leukocyte tethering or rolling(GO:1903237)
0.2 1.9 GO:1900383 regulation of synaptic plasticity by receptor localization to synapse(GO:1900383)
0.2 2.2 GO:0050765 negative regulation of phagocytosis(GO:0050765)
0.2 0.5 GO:1903061 regulation of protein lipidation(GO:1903059) positive regulation of protein lipidation(GO:1903061)
0.2 2.3 GO:0070932 histone H3 deacetylation(GO:0070932)
0.2 0.5 GO:0008612 peptidyl-lysine modification to peptidyl-hypusine(GO:0008612)
0.2 2.9 GO:0033169 histone H3-K9 demethylation(GO:0033169)
0.2 5.4 GO:0032728 positive regulation of interferon-beta production(GO:0032728)
0.2 0.5 GO:1903336 negative regulation of vacuolar transport(GO:1903336)
0.1 0.6 GO:0003430 growth plate cartilage chondrocyte growth(GO:0003430)
0.1 0.8 GO:0060267 positive regulation of respiratory burst(GO:0060267)
0.1 0.5 GO:0006624 vacuolar protein processing(GO:0006624)
0.1 0.4 GO:1903070 negative regulation of ER-associated ubiquitin-dependent protein catabolic process(GO:1903070)
0.1 0.4 GO:2001180 negative regulation of interleukin-18 production(GO:0032701) negative regulation of interleukin-10 secretion(GO:2001180)
0.1 0.7 GO:0097039 protein linear polyubiquitination(GO:0097039)
0.1 0.4 GO:2000110 negative regulation of macrophage apoptotic process(GO:2000110)
0.1 1.7 GO:0002230 positive regulation of defense response to virus by host(GO:0002230)
0.1 0.7 GO:0016557 peroxisome membrane biogenesis(GO:0016557) regulation of peroxisome size(GO:0044375)
0.1 1.6 GO:0034497 protein localization to pre-autophagosomal structure(GO:0034497)
0.1 1.0 GO:0060662 tube lumen cavitation(GO:0060605) salivary gland cavitation(GO:0060662)
0.1 0.4 GO:0010637 negative regulation of mitochondrial fusion(GO:0010637)
0.1 0.4 GO:0032962 positive regulation of inositol trisphosphate biosynthetic process(GO:0032962)
0.1 6.1 GO:2001238 positive regulation of extrinsic apoptotic signaling pathway(GO:2001238)
0.1 9.0 GO:0016525 negative regulation of angiogenesis(GO:0016525)
0.1 2.9 GO:0034340 response to type I interferon(GO:0034340)
0.1 0.3 GO:2000619 negative regulation of histone H4-K16 acetylation(GO:2000619)
0.1 0.4 GO:2000318 positive regulation of T-helper 17 type immune response(GO:2000318)
0.1 1.6 GO:0015809 arginine transport(GO:0015809)
0.1 2.5 GO:0070207 protein homotrimerization(GO:0070207)
0.1 0.4 GO:1902774 late endosome to lysosome transport(GO:1902774)
0.1 0.6 GO:0010747 positive regulation of plasma membrane long-chain fatty acid transport(GO:0010747)
0.1 0.3 GO:0060437 lung growth(GO:0060437)
0.1 1.0 GO:0002042 cell migration involved in sprouting angiogenesis(GO:0002042)
0.1 0.8 GO:2001054 negative regulation of mesenchymal cell apoptotic process(GO:2001054)
0.1 1.0 GO:0036296 cellular response to increased oxygen levels(GO:0036295) response to increased oxygen levels(GO:0036296)
0.1 0.8 GO:0070574 cadmium ion transport(GO:0015691) cadmium ion transmembrane transport(GO:0070574)
0.1 0.2 GO:0043323 positive regulation of natural killer cell degranulation(GO:0043323)
0.1 0.6 GO:0090037 positive regulation of protein kinase C signaling(GO:0090037)
0.1 0.7 GO:0048102 autophagic cell death(GO:0048102)
0.1 0.4 GO:1903966 monounsaturated fatty acid metabolic process(GO:1903964) monounsaturated fatty acid biosynthetic process(GO:1903966)
0.1 1.3 GO:0006883 cellular sodium ion homeostasis(GO:0006883)
0.1 0.3 GO:2000211 regulation of glutamate metabolic process(GO:2000211)
0.1 0.3 GO:0010726 positive regulation of hydrogen peroxide metabolic process(GO:0010726)
0.1 0.3 GO:0035696 monocyte extravasation(GO:0035696) regulation of monocyte extravasation(GO:2000437)
0.1 0.3 GO:0051045 negative regulation of membrane protein ectodomain proteolysis(GO:0051045)
0.1 1.9 GO:0010107 potassium ion import(GO:0010107)
0.1 0.9 GO:0032482 Rab protein signal transduction(GO:0032482)
0.1 0.9 GO:0032695 negative regulation of interleukin-12 production(GO:0032695)
0.1 0.8 GO:0019511 peptidyl-proline hydroxylation(GO:0019511)
0.1 0.3 GO:2000002 negative regulation of DNA damage checkpoint(GO:2000002)
0.1 0.4 GO:0010724 regulation of definitive erythrocyte differentiation(GO:0010724)
0.1 0.3 GO:0046726 positive regulation by virus of viral protein levels in host cell(GO:0046726)
0.1 0.2 GO:0035880 cell proliferation in midbrain(GO:0033278) embryonic nail plate morphogenesis(GO:0035880)
0.1 1.2 GO:0030213 hyaluronan biosynthetic process(GO:0030213)
0.1 0.8 GO:0006817 phosphate ion transport(GO:0006817)
0.1 0.5 GO:1901098 positive regulation of autophagosome maturation(GO:1901098)
0.1 0.9 GO:0048680 positive regulation of axon regeneration(GO:0048680)
0.1 2.7 GO:0000038 very long-chain fatty acid metabolic process(GO:0000038)
0.1 1.3 GO:0008210 estrogen metabolic process(GO:0008210)
0.1 0.5 GO:0042226 interleukin-6 biosynthetic process(GO:0042226) regulation of interleukin-6 biosynthetic process(GO:0045408)
0.1 0.6 GO:0031087 deadenylation-dependent decapping of nuclear-transcribed mRNA(GO:0000290) deadenylation-independent decapping of nuclear-transcribed mRNA(GO:0031087)
0.1 0.6 GO:0000395 mRNA 5'-splice site recognition(GO:0000395)
0.1 0.2 GO:0001803 antibody-dependent cellular cytotoxicity(GO:0001788) type III hypersensitivity(GO:0001802) regulation of type III hypersensitivity(GO:0001803) positive regulation of type III hypersensitivity(GO:0001805)
0.1 0.4 GO:0071630 nucleus-associated proteasomal ubiquitin-dependent protein catabolic process(GO:0071630)
0.1 0.5 GO:0046415 urate metabolic process(GO:0046415)
0.1 0.5 GO:0097369 sodium ion import(GO:0097369) sodium ion import across plasma membrane(GO:0098719) sodium ion import into cell(GO:1990118)
0.1 0.4 GO:0045218 zonula adherens maintenance(GO:0045218)
0.1 1.7 GO:0035162 embryonic hemopoiesis(GO:0035162)
0.1 0.2 GO:0070358 actin polymerization-dependent cell motility(GO:0070358)
0.1 0.5 GO:0061042 vascular wound healing(GO:0061042)
0.1 0.7 GO:0045602 negative regulation of endothelial cell differentiation(GO:0045602)
0.1 0.6 GO:0019227 neuronal action potential propagation(GO:0019227) action potential propagation(GO:0098870)
0.1 1.0 GO:0045792 negative regulation of cell size(GO:0045792)
0.1 0.2 GO:1901668 regulation of superoxide dismutase activity(GO:1901668)
0.1 0.2 GO:0002002 regulation of angiotensin levels in blood(GO:0002002)
0.1 0.3 GO:0035509 negative regulation of myosin-light-chain-phosphatase activity(GO:0035509)
0.1 0.1 GO:1904192 cholangiocyte apoptotic process(GO:1902488) regulation of cholangiocyte apoptotic process(GO:1904192) negative regulation of cholangiocyte apoptotic process(GO:1904193)
0.1 0.4 GO:0050882 voluntary musculoskeletal movement(GO:0050882)
0.1 1.0 GO:0010669 epithelial structure maintenance(GO:0010669)
0.1 1.0 GO:0030947 regulation of vascular endothelial growth factor receptor signaling pathway(GO:0030947)
0.1 0.4 GO:0042730 fibrinolysis(GO:0042730)
0.1 0.1 GO:0097051 establishment of protein localization to endoplasmic reticulum membrane(GO:0097051)
0.1 0.4 GO:0031293 membrane protein intracellular domain proteolysis(GO:0031293)
0.1 0.2 GO:0090365 regulation of mRNA modification(GO:0090365)
0.1 0.9 GO:2000310 regulation of N-methyl-D-aspartate selective glutamate receptor activity(GO:2000310)
0.1 1.4 GO:0002091 negative regulation of receptor internalization(GO:0002091)
0.0 1.0 GO:0007095 mitotic G2 DNA damage checkpoint(GO:0007095)
0.0 0.7 GO:0032516 positive regulation of phosphoprotein phosphatase activity(GO:0032516)
0.0 0.6 GO:1902083 negative regulation of peptidyl-cysteine S-nitrosylation(GO:1902083)
0.0 1.2 GO:0001921 positive regulation of receptor recycling(GO:0001921)
0.0 0.2 GO:2000671 regulation of motor neuron apoptotic process(GO:2000671)
0.0 0.3 GO:0017196 N-terminal peptidyl-methionine acetylation(GO:0017196)
0.0 1.2 GO:0046854 phosphatidylinositol phosphorylation(GO:0046854)
0.0 0.3 GO:0048149 behavioral response to ethanol(GO:0048149)
0.0 0.1 GO:0098501 polynucleotide dephosphorylation(GO:0098501)
0.0 0.5 GO:0045730 respiratory burst(GO:0045730)
0.0 0.2 GO:0006447 regulation of translational initiation by iron(GO:0006447) positive regulation of translational initiation by iron(GO:0045994)
0.0 0.2 GO:0071285 cellular response to lithium ion(GO:0071285)
0.0 1.0 GO:0033622 integrin activation(GO:0033622)
0.0 0.2 GO:0006868 glutamine transport(GO:0006868)
0.0 1.9 GO:0007157 heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0007157)
0.0 0.9 GO:0035458 cellular response to interferon-beta(GO:0035458)
0.0 2.0 GO:0071277 cellular response to calcium ion(GO:0071277)
0.0 0.2 GO:0051534 negative regulation of NFAT protein import into nucleus(GO:0051534)
0.0 0.9 GO:0010996 response to auditory stimulus(GO:0010996)
0.0 0.4 GO:0048672 positive regulation of collateral sprouting(GO:0048672)
0.0 0.4 GO:0000479 endonucleolytic cleavage of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000479)
0.0 1.4 GO:0034605 cellular response to heat(GO:0034605)
0.0 1.1 GO:0051567 histone H3-K9 methylation(GO:0051567)
0.0 1.0 GO:0006376 mRNA splice site selection(GO:0006376)
0.0 0.5 GO:0006903 vesicle targeting(GO:0006903)
0.0 0.1 GO:1900170 negative regulation of glucocorticoid mediated signaling pathway(GO:1900170)
0.0 0.5 GO:0071157 negative regulation of cell cycle arrest(GO:0071157)
0.0 0.1 GO:0002457 T cell antigen processing and presentation(GO:0002457)
0.0 0.1 GO:0002322 B cell proliferation involved in immune response(GO:0002322)
0.0 0.1 GO:2000850 cortisol secretion(GO:0043400) regulation of cortisol secretion(GO:0051462) negative regulation of corticosteroid hormone secretion(GO:2000847) negative regulation of glucocorticoid secretion(GO:2000850)
0.0 0.1 GO:0071361 cellular response to ethanol(GO:0071361)
0.0 1.3 GO:0003073 regulation of systemic arterial blood pressure(GO:0003073)
0.0 0.2 GO:1903003 positive regulation of protein deubiquitination(GO:1903003)
0.0 0.8 GO:0071300 cellular response to retinoic acid(GO:0071300)
0.0 0.2 GO:0097094 craniofacial suture morphogenesis(GO:0097094)
0.0 0.2 GO:0006013 mannose metabolic process(GO:0006013)
0.0 0.3 GO:0035455 response to interferon-alpha(GO:0035455)
0.0 0.2 GO:0031848 protection from non-homologous end joining at telomere(GO:0031848)
0.0 1.1 GO:2000649 regulation of sodium ion transmembrane transporter activity(GO:2000649)
0.0 0.2 GO:0071625 vocalization behavior(GO:0071625)
0.0 1.7 GO:0021766 hippocampus development(GO:0021766)
0.0 0.2 GO:0006102 isocitrate metabolic process(GO:0006102)
0.0 0.2 GO:0021785 branchiomotor neuron axon guidance(GO:0021785) limb bud formation(GO:0060174)
0.0 0.5 GO:0032011 ARF protein signal transduction(GO:0032011) regulation of ARF protein signal transduction(GO:0032012)
0.0 0.1 GO:0016559 peroxisome fission(GO:0016559)
0.0 0.3 GO:0048268 clathrin coat assembly(GO:0048268)
0.0 0.3 GO:0043666 regulation of phosphoprotein phosphatase activity(GO:0043666)
0.0 0.2 GO:0006388 tRNA splicing, via endonucleolytic cleavage and ligation(GO:0006388)
0.0 2.3 GO:0007416 synapse assembly(GO:0007416)
0.0 0.1 GO:0021993 initiation of neural tube closure(GO:0021993)
0.0 1.4 GO:0090630 activation of GTPase activity(GO:0090630)
0.0 0.1 GO:1904637 response to ionomycin(GO:1904636) cellular response to ionomycin(GO:1904637)
0.0 0.3 GO:0032091 negative regulation of protein binding(GO:0032091)
0.0 2.4 GO:0008654 phospholipid biosynthetic process(GO:0008654)
0.0 0.6 GO:0051591 response to cAMP(GO:0051591)
0.0 0.8 GO:0010923 negative regulation of phosphatase activity(GO:0010923)
0.0 0.1 GO:0002051 osteoblast fate commitment(GO:0002051)
0.0 0.6 GO:0030593 neutrophil chemotaxis(GO:0030593)
0.0 0.2 GO:0006353 DNA-templated transcription, termination(GO:0006353)
0.0 0.3 GO:2000401 regulation of lymphocyte migration(GO:2000401)
0.0 0.2 GO:0032933 response to sterol depletion(GO:0006991) SREBP signaling pathway(GO:0032933) cellular response to sterol depletion(GO:0071501)
0.0 0.2 GO:0051382 kinetochore assembly(GO:0051382)
0.0 0.5 GO:0031122 cytoplasmic microtubule organization(GO:0031122)
0.0 0.1 GO:0043313 regulation of neutrophil degranulation(GO:0043313) regulation of neutrophil activation(GO:1902563)
0.0 1.1 GO:0098656 anion transmembrane transport(GO:0098656)
0.0 0.0 GO:0010756 positive regulation of plasminogen activation(GO:0010756)
0.0 0.1 GO:0016584 nucleosome positioning(GO:0016584)
0.0 0.1 GO:1904659 glucose transmembrane transport(GO:1904659)
0.0 0.5 GO:0006418 tRNA aminoacylation for protein translation(GO:0006418)
0.0 0.1 GO:0043353 enucleate erythrocyte differentiation(GO:0043353)
0.0 0.3 GO:1903146 regulation of mitophagy(GO:1903146)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
1.1 3.4 GO:0097058 CRLF-CLCF1 complex(GO:0097058)
0.9 3.5 GO:0031092 platelet alpha granule membrane(GO:0031092)
0.8 3.3 GO:0042105 alpha-beta T cell receptor complex(GO:0042105)
0.5 2.5 GO:0030485 smooth muscle contractile fiber(GO:0030485)
0.5 1.5 GO:0043512 inhibin-betaglycan-ActRII complex(GO:0034673) inhibin A complex(GO:0043512)
0.4 2.4 GO:0097443 sorting endosome(GO:0097443)
0.4 2.3 GO:0046696 lipopolysaccharide receptor complex(GO:0046696)
0.3 1.0 GO:0045160 myosin I complex(GO:0045160)
0.3 1.2 GO:1990415 Pex17p-Pex14p docking complex(GO:1990415) peroxisomal importomer complex(GO:1990429)
0.2 0.7 GO:0030690 Noc1p-Noc2p complex(GO:0030690)
0.2 1.0 GO:0098843 postsynaptic endocytic zone(GO:0098843)
0.2 0.9 GO:0008282 ATP-sensitive potassium channel complex(GO:0008282)
0.2 2.8 GO:0005952 cAMP-dependent protein kinase complex(GO:0005952)
0.2 22.0 GO:0000118 histone deacetylase complex(GO:0000118)
0.2 2.4 GO:0034361 very-low-density lipoprotein particle(GO:0034361) triglyceride-rich lipoprotein particle(GO:0034385)
0.2 0.5 GO:0036488 CHOP-C/EBP complex(GO:0036488)
0.2 0.7 GO:0071797 LUBAC complex(GO:0071797)
0.1 1.5 GO:0001739 sex chromatin(GO:0001739)
0.1 0.5 GO:0016012 sarcoglycan complex(GO:0016012)
0.1 0.5 GO:0031673 H zone(GO:0031673)
0.1 0.6 GO:0043020 NADPH oxidase complex(GO:0043020)
0.1 1.2 GO:0031091 platelet alpha granule(GO:0031091)
0.1 0.5 GO:0043202 lysosomal lumen(GO:0043202)
0.1 4.6 GO:0005891 voltage-gated calcium channel complex(GO:0005891)
0.1 1.5 GO:0034045 pre-autophagosomal structure membrane(GO:0034045)
0.1 1.9 GO:0008074 guanylate cyclase complex, soluble(GO:0008074)
0.1 1.6 GO:0031528 microvillus membrane(GO:0031528)
0.1 0.4 GO:0060053 neurofilament cytoskeleton(GO:0060053)
0.1 0.7 GO:0042629 mast cell granule(GO:0042629)
0.1 1.0 GO:0031931 TORC1 complex(GO:0031931)
0.1 1.6 GO:0030139 endocytic vesicle(GO:0030139)
0.1 0.8 GO:0033180 proton-transporting V-type ATPase, V1 domain(GO:0033180)
0.1 0.3 GO:0016602 CCAAT-binding factor complex(GO:0016602)
0.1 0.5 GO:1990316 ATG1/ULK1 kinase complex(GO:1990316)
0.1 1.4 GO:0032279 asymmetric synapse(GO:0032279)
0.1 1.5 GO:0001891 phagocytic cup(GO:0001891)
0.1 0.3 GO:0034750 Scrib-APC-beta-catenin complex(GO:0034750)
0.1 0.8 GO:0097449 astrocyte projection(GO:0097449)
0.1 1.0 GO:0016460 myosin II complex(GO:0016460)
0.1 4.9 GO:0072562 blood microparticle(GO:0072562)
0.1 0.4 GO:0097255 R2TP complex(GO:0097255)
0.0 0.8 GO:0044300 cerebellar mossy fiber(GO:0044300)
0.0 0.4 GO:0031362 anchored component of external side of plasma membrane(GO:0031362)
0.0 0.2 GO:1990130 Iml1 complex(GO:1990130)
0.0 2.0 GO:0032809 neuronal cell body membrane(GO:0032809)
0.0 0.5 GO:0005677 chromatin silencing complex(GO:0005677)
0.0 0.2 GO:0070826 paraferritin complex(GO:0070826)
0.0 1.9 GO:0030131 clathrin adaptor complex(GO:0030131)
0.0 0.4 GO:0070765 gamma-secretase complex(GO:0070765)
0.0 0.6 GO:0035631 CD40 receptor complex(GO:0035631)
0.0 2.1 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.0 4.5 GO:0031225 anchored component of membrane(GO:0031225)
0.0 0.4 GO:0000138 Golgi trans cisterna(GO:0000138)
0.0 2.3 GO:0005902 microvillus(GO:0005902)
0.0 0.3 GO:0030688 preribosome, small subunit precursor(GO:0030688)
0.0 0.1 GO:0019815 immunoglobulin complex(GO:0019814) B cell receptor complex(GO:0019815)
0.0 0.6 GO:0001518 voltage-gated sodium channel complex(GO:0001518)
0.0 1.8 GO:0045171 intercellular bridge(GO:0045171)
0.0 0.4 GO:0005915 zonula adherens(GO:0005915)
0.0 1.5 GO:0005719 nuclear euchromatin(GO:0005719)
0.0 0.4 GO:0016589 NURF complex(GO:0016589)
0.0 0.9 GO:0030687 preribosome, large subunit precursor(GO:0030687)
0.0 0.3 GO:0005892 acetylcholine-gated channel complex(GO:0005892)
0.0 0.5 GO:0030119 AP-type membrane coat adaptor complex(GO:0030119)
0.0 0.3 GO:0042588 zymogen granule(GO:0042588)
0.0 0.3 GO:0005688 U6 snRNP(GO:0005688)
0.0 0.1 GO:0042583 chromaffin granule(GO:0042583)
0.0 2.5 GO:0000139 Golgi membrane(GO:0000139)
0.0 0.5 GO:0008305 integrin complex(GO:0008305) protein complex involved in cell adhesion(GO:0098636)
0.0 0.7 GO:0005779 integral component of peroxisomal membrane(GO:0005779)
0.0 0.6 GO:0005721 pericentric heterochromatin(GO:0005721)
0.0 0.3 GO:0031414 N-terminal protein acetyltransferase complex(GO:0031414)
0.0 0.2 GO:0072669 tRNA-splicing ligase complex(GO:0072669)
0.0 0.1 GO:0070695 FHF complex(GO:0070695)
0.0 1.0 GO:0044295 axonal growth cone(GO:0044295)
0.0 1.4 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.0 1.2 GO:0042734 presynaptic membrane(GO:0042734)
0.0 0.8 GO:0010494 cytoplasmic stress granule(GO:0010494)
0.0 0.3 GO:0030285 integral component of synaptic vesicle membrane(GO:0030285) intrinsic component of synaptic vesicle membrane(GO:0098563)
0.0 0.2 GO:0017146 NMDA selective glutamate receptor complex(GO:0017146)
0.0 0.2 GO:0031527 filopodium membrane(GO:0031527)
0.0 9.8 GO:0009986 cell surface(GO:0009986)
0.0 1.5 GO:0043204 perikaryon(GO:0043204)
0.0 0.4 GO:0035371 microtubule plus-end(GO:0035371)
0.0 0.5 GO:0005802 trans-Golgi network(GO:0005802)
0.0 0.2 GO:0098799 outer mitochondrial membrane protein complex(GO:0098799)
0.0 3.0 GO:0045211 postsynaptic membrane(GO:0045211)
0.0 0.2 GO:0070419 nonhomologous end joining complex(GO:0070419)
0.0 0.6 GO:0030173 integral component of Golgi membrane(GO:0030173)
0.0 0.5 GO:0031941 filamentous actin(GO:0031941)
0.0 0.2 GO:0016327 apicolateral plasma membrane(GO:0016327)
0.0 1.6 GO:0000922 spindle pole(GO:0000922)
0.0 0.7 GO:0000307 cyclin-dependent protein kinase holoenzyme complex(GO:0000307)
0.0 0.3 GO:0005905 clathrin-coated pit(GO:0005905)
0.0 0.4 GO:0016323 basolateral plasma membrane(GO:0016323)
0.0 35.6 GO:0016021 integral component of membrane(GO:0016021)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
2.2 15.5 GO:0052650 NADP-retinol dehydrogenase activity(GO:0052650)
0.9 4.5 GO:0038085 vascular endothelial growth factor binding(GO:0038085)
0.8 2.4 GO:0034437 very-low-density lipoprotein particle binding(GO:0034189) glycoprotein transporter activity(GO:0034437)
0.8 2.3 GO:0001875 lipopolysaccharide receptor activity(GO:0001875)
0.8 3.0 GO:0003810 protein-glutamine gamma-glutamyltransferase activity(GO:0003810)
0.7 3.7 GO:0005534 galactose binding(GO:0005534)
0.6 2.5 GO:0004699 calcium-independent protein kinase C activity(GO:0004699)
0.6 1.7 GO:0008109 N-acetyllactosaminide beta-1,6-N-acetylglucosaminyltransferase activity(GO:0008109)
0.5 2.0 GO:0005315 inorganic phosphate transmembrane transporter activity(GO:0005315)
0.5 3.4 GO:0005127 ciliary neurotrophic factor receptor binding(GO:0005127)
0.4 1.2 GO:0001888 glucuronyl-galactosyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity(GO:0001888)
0.4 1.2 GO:0015038 glutathione disulfide oxidoreductase activity(GO:0015038)
0.4 1.1 GO:0031798 type 1 metabotropic glutamate receptor binding(GO:0031798)
0.3 1.4 GO:0004441 inositol-1,4-bisphosphate 1-phosphatase activity(GO:0004441)
0.3 1.7 GO:0019960 C-X3-C chemokine binding(GO:0019960)
0.3 2.0 GO:0001849 complement component C1q binding(GO:0001849)
0.3 0.8 GO:0005001 transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198)
0.3 5.1 GO:0005044 scavenger receptor activity(GO:0005044)
0.2 2.6 GO:0031957 very long-chain fatty acid-CoA ligase activity(GO:0031957)
0.2 0.7 GO:0098639 collagen binding involved in cell-matrix adhesion(GO:0098639)
0.2 0.9 GO:0008853 exodeoxyribonuclease III activity(GO:0008853)
0.2 0.8 GO:0005021 vascular endothelial growth factor-activated receptor activity(GO:0005021)
0.2 5.3 GO:0005164 tumor necrosis factor receptor binding(GO:0005164)
0.2 1.6 GO:0015181 arginine transmembrane transporter activity(GO:0015181)
0.2 0.8 GO:0001639 PLC activating G-protein coupled glutamate receptor activity(GO:0001639) A2A adenosine receptor binding(GO:0031687) G-protein coupled receptor activity involved in regulation of postsynaptic membrane potential(GO:0099530)
0.2 1.2 GO:0000298 endopolyphosphatase activity(GO:0000298) diphosphoinositol-polyphosphate diphosphatase activity(GO:0008486) bis(5'-adenosyl)-hexaphosphatase activity(GO:0034431) bis(5'-adenosyl)-pentaphosphatase activity(GO:0034432)
0.2 3.0 GO:0042809 vitamin D receptor binding(GO:0042809)
0.2 1.3 GO:0001609 G-protein coupled adenosine receptor activity(GO:0001609) heterotrimeric G-protein binding(GO:0032795)
0.2 1.0 GO:1990430 extracellular matrix protein binding(GO:1990430)
0.2 1.5 GO:0034711 inhibin binding(GO:0034711)
0.2 1.3 GO:0043423 3-phosphoinositide-dependent protein kinase binding(GO:0043423)
0.2 1.9 GO:0004016 adenylate cyclase activity(GO:0004016)
0.2 0.5 GO:0004348 glucosylceramidase activity(GO:0004348)
0.2 1.4 GO:0005007 fibroblast growth factor-activated receptor activity(GO:0005007)
0.2 0.6 GO:0016175 superoxide-generating NADPH oxidase activity(GO:0016175)
0.2 2.0 GO:0017081 chloride channel regulator activity(GO:0017081)
0.1 3.2 GO:0001968 fibronectin binding(GO:0001968)
0.1 0.4 GO:0015140 malate transmembrane transporter activity(GO:0015140)
0.1 1.3 GO:0030274 LIM domain binding(GO:0030274)
0.1 2.9 GO:0003841 1-acylglycerol-3-phosphate O-acyltransferase activity(GO:0003841)
0.1 0.5 GO:0015143 urate transmembrane transporter activity(GO:0015143) salt transmembrane transporter activity(GO:1901702)
0.1 0.6 GO:0003839 gamma-glutamylcyclotransferase activity(GO:0003839)
0.1 0.4 GO:0034511 U3 snoRNA binding(GO:0034511)
0.1 3.6 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
0.1 0.2 GO:0004105 choline-phosphate cytidylyltransferase activity(GO:0004105)
0.1 0.9 GO:0005025 transforming growth factor beta receptor activity, type I(GO:0005025)
0.1 0.4 GO:0070012 oligopeptidase activity(GO:0070012)
0.1 0.4 GO:0032896 palmitoyl-CoA 9-desaturase activity(GO:0032896)
0.1 0.7 GO:0003886 DNA (cytosine-5-)-methyltransferase activity(GO:0003886)
0.1 0.7 GO:0070290 N-acylphosphatidylethanolamine-specific phospholipase D activity(GO:0070290)
0.1 0.2 GO:0005110 frizzled-2 binding(GO:0005110)
0.1 1.1 GO:0005225 volume-sensitive anion channel activity(GO:0005225)
0.1 0.8 GO:0031543 peptidyl-proline dioxygenase activity(GO:0031543)
0.1 0.2 GO:0004534 transcription termination site sequence-specific DNA binding(GO:0001147) transcription termination site DNA binding(GO:0001160) 5'-3' exoribonuclease activity(GO:0004534)
0.1 0.4 GO:1904288 BAT3 complex binding(GO:1904288)
0.1 0.7 GO:0003993 acid phosphatase activity(GO:0003993)
0.1 0.4 GO:0003835 beta-galactoside alpha-2,6-sialyltransferase activity(GO:0003835)
0.1 1.4 GO:0042043 neurexin family protein binding(GO:0042043)
0.1 4.4 GO:0005518 collagen binding(GO:0005518)
0.1 1.0 GO:0008331 high voltage-gated calcium channel activity(GO:0008331)
0.1 1.2 GO:0031702 type 1 angiotensin receptor binding(GO:0031702)
0.1 0.7 GO:0004691 cAMP-dependent protein kinase activity(GO:0004691)
0.1 1.3 GO:0005035 tumor necrosis factor-activated receptor activity(GO:0005031) death receptor activity(GO:0005035)
0.1 0.8 GO:0017154 semaphorin receptor activity(GO:0017154)
0.1 0.3 GO:0004111 creatine kinase activity(GO:0004111)
0.1 1.0 GO:0030898 actin-dependent ATPase activity(GO:0030898)
0.1 0.6 GO:0016428 tRNA (cytosine-5-)-methyltransferase activity(GO:0016428)
0.1 0.9 GO:0017166 vinculin binding(GO:0017166)
0.1 0.4 GO:0051525 NFAT protein binding(GO:0051525)
0.1 0.5 GO:0015386 potassium:proton antiporter activity(GO:0015386)
0.1 1.5 GO:0080025 phosphatidylinositol-3,5-bisphosphate binding(GO:0080025)
0.1 0.3 GO:0019961 interferon binding(GO:0019961)
0.1 0.4 GO:0015379 potassium:chloride symporter activity(GO:0015379) potassium ion symporter activity(GO:0022820)
0.1 0.2 GO:0004449 isocitrate dehydrogenase (NAD+) activity(GO:0004449)
0.1 0.7 GO:0008349 MAP kinase kinase kinase kinase activity(GO:0008349)
0.0 0.5 GO:0045236 CXCR chemokine receptor binding(GO:0045236)
0.0 0.6 GO:0004467 long-chain fatty acid-CoA ligase activity(GO:0004467) decanoate--CoA ligase activity(GO:0102391)
0.0 1.1 GO:0031078 histone deacetylase activity (H3-K14 specific)(GO:0031078) NAD-dependent histone deacetylase activity (H3-K14 specific)(GO:0032041)
0.0 0.2 GO:0015086 cadmium ion transmembrane transporter activity(GO:0015086) lead ion transmembrane transporter activity(GO:0015094) vanadium ion transmembrane transporter activity(GO:0015100) ferrous iron uptake transmembrane transporter activity(GO:0015639)
0.0 1.3 GO:0043014 alpha-tubulin binding(GO:0043014)
0.0 0.6 GO:0003708 retinoic acid receptor activity(GO:0003708)
0.0 4.8 GO:0008013 beta-catenin binding(GO:0008013)
0.0 0.5 GO:0008190 eukaryotic initiation factor 4E binding(GO:0008190)
0.0 0.6 GO:0070679 inositol 1,4,5 trisphosphate binding(GO:0070679)
0.0 0.2 GO:0008545 JUN kinase kinase activity(GO:0008545)
0.0 2.1 GO:0004714 transmembrane receptor protein tyrosine kinase activity(GO:0004714)
0.0 0.2 GO:0019770 IgG receptor activity(GO:0019770)
0.0 1.0 GO:0004709 MAP kinase kinase kinase activity(GO:0004709)
0.0 0.2 GO:0001847 opsonin receptor activity(GO:0001847)
0.0 0.8 GO:0030215 semaphorin receptor binding(GO:0030215)
0.0 0.2 GO:0015186 L-glutamine transmembrane transporter activity(GO:0015186)
0.0 0.5 GO:0043325 phosphatidylinositol-3,4-bisphosphate binding(GO:0043325)
0.0 1.4 GO:0017080 sodium channel regulator activity(GO:0017080)
0.0 0.8 GO:0005547 phosphatidylinositol-3,4,5-trisphosphate binding(GO:0005547)
0.0 0.1 GO:0038049 glucocorticoid receptor activity(GO:0004883) transcription factor activity, ligand-activated RNA polymerase II transcription factor binding(GO:0038049) glucocorticoid-activated RNA polymerase II transcription factor binding transcription factor activity(GO:0038051)
0.0 2.9 GO:0008083 growth factor activity(GO:0008083)
0.0 1.7 GO:0046875 ephrin receptor binding(GO:0046875)
0.0 0.8 GO:0046961 proton-transporting ATPase activity, rotational mechanism(GO:0046961)
0.0 0.3 GO:0005068 transmembrane receptor protein tyrosine kinase adaptor activity(GO:0005068)
0.0 0.7 GO:0008009 chemokine activity(GO:0008009)
0.0 1.1 GO:0070491 repressing transcription factor binding(GO:0070491)
0.0 0.5 GO:0035612 AP-2 adaptor complex binding(GO:0035612)
0.0 0.6 GO:0005242 inward rectifier potassium channel activity(GO:0005242)
0.0 1.4 GO:1990782 protein tyrosine kinase binding(GO:1990782)
0.0 3.4 GO:0005089 Rho guanyl-nucleotide exchange factor activity(GO:0005089)
0.0 0.2 GO:0035312 5'-3' exodeoxyribonuclease activity(GO:0035312)
0.0 4.8 GO:0017124 SH3 domain binding(GO:0017124)
0.0 0.6 GO:0005248 voltage-gated sodium channel activity(GO:0005248)
0.0 0.4 GO:0008569 ATP-dependent microtubule motor activity, minus-end-directed(GO:0008569)
0.0 1.6 GO:0030276 clathrin binding(GO:0030276)
0.0 0.3 GO:0042379 chemokine receptor binding(GO:0042379)
0.0 1.2 GO:0004693 cyclin-dependent protein serine/threonine kinase activity(GO:0004693)
0.0 2.0 GO:0008201 heparin binding(GO:0008201)
0.0 0.7 GO:0030551 cyclic nucleotide binding(GO:0030551)
0.0 0.1 GO:0046403 polynucleotide 3'-phosphatase activity(GO:0046403)
0.0 3.1 GO:0005085 guanyl-nucleotide exchange factor activity(GO:0005085)
0.0 0.2 GO:0042301 phosphate ion binding(GO:0042301)
0.0 0.3 GO:0004596 peptide alpha-N-acetyltransferase activity(GO:0004596)
0.0 0.3 GO:0043008 ATP-dependent protein binding(GO:0043008)
0.0 0.1 GO:0097003 adipokinetic hormone receptor activity(GO:0097003)
0.0 0.9 GO:0070888 E-box binding(GO:0070888)
0.0 0.3 GO:0017075 syntaxin-1 binding(GO:0017075)
0.0 0.4 GO:0035613 RNA stem-loop binding(GO:0035613)
0.0 0.6 GO:0050699 WW domain binding(GO:0050699)
0.0 0.6 GO:0004683 calmodulin-dependent protein kinase activity(GO:0004683)
0.0 0.2 GO:0003680 AT DNA binding(GO:0003680)
0.0 10.3 GO:0003682 chromatin binding(GO:0003682)
0.0 0.6 GO:0035035 histone acetyltransferase binding(GO:0035035)
0.0 0.2 GO:0034450 ubiquitin-ubiquitin ligase activity(GO:0034450)
0.0 0.4 GO:0071889 14-3-3 protein binding(GO:0071889)
0.0 0.9 GO:0015459 potassium channel regulator activity(GO:0015459)
0.0 0.6 GO:0008536 Ran GTPase binding(GO:0008536)
0.0 0.2 GO:0004559 alpha-mannosidase activity(GO:0004559)
0.0 0.2 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.0 0.2 GO:0004181 metallocarboxypeptidase activity(GO:0004181)
0.0 0.2 GO:1990381 ubiquitin-specific protease binding(GO:1990381)
0.0 0.1 GO:0017151 DEAD/H-box RNA helicase binding(GO:0017151)
0.0 0.4 GO:0031624 ubiquitin conjugating enzyme binding(GO:0031624)
0.0 0.4 GO:0005484 SNAP receptor activity(GO:0005484)
0.0 0.3 GO:0008157 protein phosphatase 1 binding(GO:0008157)
0.0 0.5 GO:0016876 aminoacyl-tRNA ligase activity(GO:0004812) ligase activity, forming carbon-oxygen bonds(GO:0016875) ligase activity, forming aminoacyl-tRNA and related compounds(GO:0016876)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 16.1 PID_TAP63_PATHWAY Validated transcriptional targets of TAp63 isoforms
0.2 2.3 PID_VEGF_VEGFR_PATHWAY VEGF and VEGFR signaling network
0.1 2.5 PID_LPA4_PATHWAY LPA4-mediated signaling events
0.1 3.0 PID_UPA_UPAR_PATHWAY Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling
0.1 2.6 PID_INTEGRIN_A9B1_PATHWAY Alpha9 beta1 integrin signaling events
0.1 3.5 PID_INTEGRIN_A4B1_PATHWAY Alpha4 beta1 integrin signaling events
0.1 3.8 PID_ALK1_PATHWAY ALK1 signaling events
0.1 2.4 PID_TOLL_ENDOGENOUS_PATHWAY Endogenous TLR signaling
0.1 2.5 PID_PDGFRA_PATHWAY PDGFR-alpha signaling pathway
0.1 0.7 PID_INTEGRIN_CS_PATHWAY Integrin family cell surface interactions
0.1 2.8 PID_RAS_PATHWAY Regulation of Ras family activation
0.1 2.1 PID_INTEGRIN3_PATHWAY Beta3 integrin cell surface interactions
0.1 0.5 PID_IL2_1PATHWAY IL2-mediated signaling events
0.1 1.9 PID_IL12_STAT4_PATHWAY IL12 signaling mediated by STAT4
0.1 5.9 WNT_SIGNALING Genes related to Wnt-mediated signal transduction
0.1 0.4 PID_INTEGRIN2_PATHWAY Beta2 integrin cell surface interactions
0.1 9.9 NABA_SECRETED_FACTORS Genes encoding secreted soluble factors
0.0 5.8 NABA_ECM_AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.0 1.5 NABA_PROTEOGLYCANS Genes encoding proteoglycans
0.0 0.4 PID_S1P_S1P2_PATHWAY S1P2 pathway
0.0 0.8 PID_ECADHERIN_STABILIZATION_PATHWAY Stabilization and expansion of the E-cadherin adherens junction
0.0 3.1 PID_LKB1_PATHWAY LKB1 signaling events
0.0 0.7 PID_TRAIL_PATHWAY TRAIL signaling pathway
0.0 0.9 PID_ERBB1_RECEPTOR_PROXIMAL_PATHWAY EGF receptor (ErbB1) signaling pathway
0.0 1.0 PID_IL4_2PATHWAY IL4-mediated signaling events
0.0 0.8 SIG_CD40PATHWAYMAP Genes related to CD40 signaling
0.0 1.1 PID_BCR_5PATHWAY BCR signaling pathway
0.0 1.3 PID_INSULIN_PATHWAY Insulin Pathway
0.0 0.3 ST_GRANULE_CELL_SURVIVAL_PATHWAY Granule Cell Survival Pathway is a specific case of more general PAC1 Receptor Pathway.
0.0 0.6 PID_TCR_CALCIUM_PATHWAY Calcium signaling in the CD4+ TCR pathway
0.0 1.2 ST_GAQ_PATHWAY G alpha q Pathway
0.0 1.1 PID_P38_ALPHA_BETA_DOWNSTREAM_PATHWAY Signaling mediated by p38-alpha and p38-beta
0.0 0.2 PID_FCER1_PATHWAY Fc-epsilon receptor I signaling in mast cells
0.0 0.6 PID_LYSOPHOSPHOLIPID_PATHWAY LPA receptor mediated events
0.0 0.4 PID_SYNDECAN_3_PATHWAY Syndecan-3-mediated signaling events
0.0 0.8 PID_LIS1_PATHWAY Lissencephaly gene (LIS1) in neuronal migration and development
0.0 0.1 PID_TCR_RAS_PATHWAY Ras signaling in the CD4+ TCR pathway
0.0 1.3 PID_HDAC_CLASSII_PATHWAY Signaling events mediated by HDAC Class II
0.0 0.9 PID_MET_PATHWAY Signaling events mediated by Hepatocyte Growth Factor Receptor (c-Met)
0.0 0.7 PID_BMP_PATHWAY BMP receptor signaling
0.0 0.7 PID_RETINOIC_ACID_PATHWAY Retinoic acid receptors-mediated signaling
0.0 0.6 PID_HIF2PATHWAY HIF-2-alpha transcription factor network
0.0 0.8 PID_HEDGEHOG_GLI_PATHWAY Hedgehog signaling events mediated by Gli proteins
0.0 2.3 NABA_MATRISOME_ASSOCIATED Ensemble of genes encoding ECM-associated proteins including ECM-affilaited proteins, ECM regulators and secreted factors
0.0 0.6 PID_CDC42_REG_PATHWAY Regulation of CDC42 activity
0.0 0.3 PID_DNA_PK_PATHWAY DNA-PK pathway in nonhomologous end joining
0.0 0.6 PID_TRKR_PATHWAY Neurotrophic factor-mediated Trk receptor signaling
0.0 0.3 PID_ECADHERIN_NASCENT_AJ_PATHWAY E-cadherin signaling in the nascent adherens junction
0.0 0.3 PID_FGF_PATHWAY FGF signaling pathway
0.0 0.2 PID_CDC42_PATHWAY CDC42 signaling events

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.9 2.8 REACTOME_ENDOSOMAL_VACUOLAR_PATHWAY Genes involved in Endosomal/Vacuolar pathway
0.5 3.0 REACTOME_COMMON_PATHWAY Genes involved in Common Pathway
0.4 1.5 REACTOME_GLYCOPROTEIN_HORMONES Genes involved in Glycoprotein hormones
0.3 6.1 REACTOME_IMMUNOREGULATORY_INTERACTIONS_BETWEEN_A_LYMPHOID_AND_A_NON_LYMPHOID_CELL Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
0.2 2.3 REACTOME_IKK_COMPLEX_RECRUITMENT_MEDIATED_BY_RIP1 Genes involved in IKK complex recruitment mediated by RIP1
0.2 2.3 REACTOME_VEGF_LIGAND_RECEPTOR_INTERACTIONS Genes involved in VEGF ligand-receptor interactions
0.2 3.0 REACTOME_PLATELET_SENSITIZATION_BY_LDL Genes involved in Platelet sensitization by LDL
0.2 5.9 REACTOME_DARPP_32_EVENTS Genes involved in DARPP-32 events
0.1 4.6 REACTOME_EFFECTS_OF_PIP2_HYDROLYSIS Genes involved in Effects of PIP2 hydrolysis
0.1 1.4 REACTOME_FGFR2C_LIGAND_BINDING_AND_ACTIVATION Genes involved in FGFR2c ligand binding and activation
0.1 2.9 REACTOME_CHEMOKINE_RECEPTORS_BIND_CHEMOKINES Genes involved in Chemokine receptors bind chemokines
0.1 4.3 REACTOME_EGFR_DOWNREGULATION Genes involved in EGFR downregulation
0.1 1.3 REACTOME_NUCLEOTIDE_LIKE_PURINERGIC_RECEPTORS Genes involved in Nucleotide-like (purinergic) receptors
0.1 1.3 REACTOME_IONOTROPIC_ACTIVITY_OF_KAINATE_RECEPTORS Genes involved in Ionotropic activity of Kainate Receptors
0.1 2.9 REACTOME_SYNTHESIS_OF_PA Genes involved in Synthesis of PA
0.1 0.7 REACTOME_NFKB_ACTIVATION_THROUGH_FADD_RIP1_PATHWAY_MEDIATED_BY_CASPASE_8_AND10 Genes involved in NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10
0.1 0.8 REACTOME_KERATAN_SULFATE_DEGRADATION Genes involved in Keratan sulfate degradation
0.1 2.2 REACTOME_G_BETA_GAMMA_SIGNALLING_THROUGH_PLC_BETA Genes involved in G beta:gamma signalling through PLC beta
0.1 1.8 REACTOME_GLUTATHIONE_CONJUGATION Genes involved in Glutathione conjugation
0.1 1.9 REACTOME_NITRIC_OXIDE_STIMULATES_GUANYLATE_CYCLASE Genes involved in Nitric oxide stimulates guanylate cyclase
0.1 1.8 REACTOME_ADHERENS_JUNCTIONS_INTERACTIONS Genes involved in Adherens junctions interactions
0.1 1.4 REACTOME_LATENT_INFECTION_OF_HOMO_SAPIENS_WITH_MYCOBACTERIUM_TUBERCULOSIS Genes involved in Latent infection of Homo sapiens with Mycobacterium tuberculosis
0.0 0.5 REACTOME_FACILITATIVE_NA_INDEPENDENT_GLUCOSE_TRANSPORTERS Genes involved in Facilitative Na+-independent glucose transporters
0.0 0.4 REACTOME_INTRINSIC_PATHWAY Genes involved in Intrinsic Pathway
0.0 8.2 REACTOME_SIGNALING_BY_RHO_GTPASES Genes involved in Signaling by Rho GTPases
0.0 0.3 REACTOME_CTNNB1_PHOSPHORYLATION_CASCADE Genes involved in Beta-catenin phosphorylation cascade
0.0 0.4 REACTOME_TERMINATION_OF_O_GLYCAN_BIOSYNTHESIS Genes involved in Termination of O-glycan biosynthesis
0.0 1.0 REACTOME_AKT_PHOSPHORYLATES_TARGETS_IN_THE_CYTOSOL Genes involved in AKT phosphorylates targets in the cytosol
0.0 0.9 REACTOME_OTHER_SEMAPHORIN_INTERACTIONS Genes involved in Other semaphorin interactions
0.0 0.7 REACTOME_INWARDLY_RECTIFYING_K_CHANNELS Genes involved in Inwardly rectifying K+ channels
0.0 0.8 REACTOME_CELL_EXTRACELLULAR_MATRIX_INTERACTIONS Genes involved in Cell-extracellular matrix interactions
0.0 0.6 REACTOME_ZINC_TRANSPORTERS Genes involved in Zinc transporters
0.0 0.6 REACTOME_MRNA_DECAY_BY_5_TO_3_EXORIBONUCLEASE Genes involved in mRNA Decay by 5' to 3' Exoribonuclease
0.0 0.3 REACTOME_TIE2_SIGNALING Genes involved in Tie2 Signaling
0.0 0.5 REACTOME_DEGRADATION_OF_THE_EXTRACELLULAR_MATRIX Genes involved in Degradation of the extracellular matrix
0.0 0.8 REACTOME_SIGNALING_BY_SCF_KIT Genes involved in Signaling by SCF-KIT
0.0 0.6 REACTOME_BMAL1_CLOCK_NPAS2_ACTIVATES_CIRCADIAN_EXPRESSION Genes involved in BMAL1:CLOCK/NPAS2 Activates Circadian Expression
0.0 0.5 REACTOME_G_ALPHA1213_SIGNALLING_EVENTS Genes involved in G alpha (12/13) signalling events
0.0 2.9 REACTOME_SIGNALING_BY_PDGF Genes involved in Signaling by PDGF
0.0 1.6 REACTOME_RESPONSE_TO_ELEVATED_PLATELET_CYTOSOLIC_CA2_ Genes involved in Response to elevated platelet cytosolic Ca2+
0.0 0.6 REACTOME_MITOCHONDRIAL_TRNA_AMINOACYLATION Genes involved in Mitochondrial tRNA aminoacylation
0.0 0.4 REACTOME_REGULATED_PROTEOLYSIS_OF_P75NTR Genes involved in Regulated proteolysis of p75NTR
0.0 0.6 REACTOME_SYNTHESIS_OF_VERY_LONG_CHAIN_FATTY_ACYL_COAS Genes involved in Synthesis of very long-chain fatty acyl-CoAs
0.0 0.8 REACTOME_ASSOCIATION_OF_TRIC_CCT_WITH_TARGET_PROTEINS_DURING_BIOSYNTHESIS Genes involved in Association of TriC/CCT with target proteins during biosynthesis
0.0 1.5 REACTOME_TRANSCRIPTIONAL_REGULATION_OF_WHITE_ADIPOCYTE_DIFFERENTIATION Genes involved in Transcriptional Regulation of White Adipocyte Differentiation
0.0 0.8 REACTOME_DEPOSITION_OF_NEW_CENPA_CONTAINING_NUCLEOSOMES_AT_THE_CENTROMERE Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere
0.0 0.5 REACTOME_GLYCOSPHINGOLIPID_METABOLISM Genes involved in Glycosphingolipid metabolism
0.0 0.4 REACTOME_GLUCONEOGENESIS Genes involved in Gluconeogenesis
0.0 0.2 REACTOME_JNK_C_JUN_KINASES_PHOSPHORYLATION_AND_ACTIVATION_MEDIATED_BY_ACTIVATED_HUMAN_TAK1 Genes involved in JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1
0.0 0.5 REACTOME_PPARA_ACTIVATES_GENE_EXPRESSION Genes involved in PPARA Activates Gene Expression
0.0 0.3 REACTOME_LYSOSOME_VESICLE_BIOGENESIS Genes involved in Lysosome Vesicle Biogenesis