Motif ID: Esr1

Z-value: 1.027


Transcription factors associated with Esr1:

Gene SymbolEntrez IDGene Name
Esr1 ENSMUSG00000019768.10 Esr1

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Esr1mm10_v2_chr10_+_4710119_47101660.363.0e-02Click!


Activity profile for motif Esr1.

activity profile for motif Esr1


Sorted Z-values histogram for motif Esr1

Sorted Z-values for motif Esr1



Network of associatons between targets according to the STRING database.



First level regulatory network of Esr1

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr18_-_66860458 3.587 ENSMUST00000057942.2
Mc4r
melanocortin 4 receptor
chr1_+_34579693 3.234 ENSMUST00000052670.8
Amer3
APC membrane recruitment 3
chr16_-_76373827 3.059 ENSMUST00000121927.1
Nrip1
nuclear receptor interacting protein 1
chr3_+_117575268 2.935 ENSMUST00000039564.6
4833424O15Rik
RIKEN cDNA 4833424O15 gene
chr4_-_141598206 2.911 ENSMUST00000131317.1
ENSMUST00000006381.4
ENSMUST00000129602.1
Fblim1


filamin binding LIM protein 1


chr18_-_38211957 2.645 ENSMUST00000159405.1
ENSMUST00000160721.1
Pcdh1

protocadherin 1

chr10_-_125308809 2.600 ENSMUST00000105257.2
Slc16a7
solute carrier family 16 (monocarboxylic acid transporters), member 7
chr19_-_57182293 2.593 ENSMUST00000133369.1
Ablim1
actin-binding LIM protein 1
chr1_-_87573825 2.564 ENSMUST00000068681.5
Ngef
neuronal guanine nucleotide exchange factor
chr4_+_152199805 2.544 ENSMUST00000105652.2
Acot7
acyl-CoA thioesterase 7
chr13_+_31806627 2.259 ENSMUST00000062292.2
Foxc1
forkhead box C1
chr8_-_68735058 2.198 ENSMUST00000136060.1
ENSMUST00000130214.1
ENSMUST00000078350.6
Csgalnact1


chondroitin sulfate N-acetylgalactosaminyltransferase 1


chr7_+_45699843 2.190 ENSMUST00000003360.7
Car11
carbonic anhydrase 11
chr2_-_104257400 2.175 ENSMUST00000141159.1
D430041D05Rik
RIKEN cDNA D430041D05 gene
chr1_-_43163891 2.170 ENSMUST00000008280.7
Fhl2
four and a half LIM domains 2
chr11_+_32286946 2.127 ENSMUST00000101387.3
Hbq1b
hemoglobin, theta 1B
chr5_-_77408034 2.126 ENSMUST00000163898.1
ENSMUST00000046746.6
Igfbp7

insulin-like growth factor binding protein 7

chrX_-_104857228 2.007 ENSMUST00000033575.5
Magee2
melanoma antigen, family E, 2
chr5_-_143909782 1.887 ENSMUST00000031613.4
ENSMUST00000100483.2
Aimp2

aminoacyl tRNA synthetase complex-interacting multifunctional protein 2

chr11_+_7063423 1.872 ENSMUST00000020706.4
Adcy1
adenylate cyclase 1
chr15_-_93595877 1.862 ENSMUST00000048982.4
Prickle1
prickle homolog 1 (Drosophila)
chr7_+_44310213 1.786 ENSMUST00000107938.1
Shank1
SH3/ankyrin domain gene 1
chr3_-_141931523 1.782 ENSMUST00000106232.1
Bmpr1b
bone morphogenetic protein receptor, type 1B
chr14_+_57999305 1.767 ENSMUST00000180534.1
3110083C13Rik
RIKEN cDNA 3110083C13 gene
chr12_+_109747903 1.744 ENSMUST00000183084.1
ENSMUST00000182300.1
Mirg

miRNA containing gene

chr18_-_36515798 1.739 ENSMUST00000025363.5
Hbegf
heparin-binding EGF-like growth factor
chr5_+_37185897 1.713 ENSMUST00000094840.3
Gm1043
predicted gene 1043
chr16_+_23107413 1.696 ENSMUST00000023599.6
ENSMUST00000168891.1
Eif4a2

eukaryotic translation initiation factor 4A2

chr8_+_23139030 1.672 ENSMUST00000121075.1
Ank1
ankyrin 1, erythroid
chr14_-_70635946 1.655 ENSMUST00000022695.9
Dmtn
dematin actin binding protein
chr2_-_166155272 1.648 ENSMUST00000088086.3
Sulf2
sulfatase 2
chr9_+_21184103 1.585 ENSMUST00000115458.2
Pde4a
phosphodiesterase 4A, cAMP specific
chr10_+_79716588 1.555 ENSMUST00000099513.1
ENSMUST00000020581.2
Hcn2

hyperpolarization-activated, cyclic nucleotide-gated K+ 2

chr6_+_22875496 1.550 ENSMUST00000090568.3
Ptprz1
protein tyrosine phosphatase, receptor type Z, polypeptide 1
chr14_-_57398483 1.533 ENSMUST00000022517.7
Cryl1
crystallin, lambda 1
chr4_-_49597425 1.531 ENSMUST00000150664.1
Tmem246
transmembrane protein 246
chr5_-_147076482 1.488 ENSMUST00000016664.7
Lnx2
ligand of numb-protein X 2
chr2_-_181314500 1.488 ENSMUST00000103045.3
Stmn3
stathmin-like 3
chr5_+_127632238 1.453 ENSMUST00000118139.1
Glt1d1
glycosyltransferase 1 domain containing 1
chr15_-_64060439 1.429 ENSMUST00000063838.4
Fam49b
family with sequence similarity 49, member B
chr17_-_35175995 1.428 ENSMUST00000173324.1
Aif1
allograft inflammatory factor 1
chr4_-_139075557 1.424 ENSMUST00000105802.1
Htr6
5-hydroxytryptamine (serotonin) receptor 6
chr11_+_97415527 1.406 ENSMUST00000121799.1
Arhgap23
Rho GTPase activating protein 23
chr18_-_74961252 1.395 ENSMUST00000066532.4
Lipg
lipase, endothelial
chr19_+_58728887 1.385 ENSMUST00000048644.5
Pnliprp1
pancreatic lipase related protein 1
chr2_+_156421083 1.374 ENSMUST00000125153.2
ENSMUST00000103136.1
ENSMUST00000109577.2
Epb4.1l1


erythrocyte protein band 4.1-like 1


chr17_+_34629533 1.370 ENSMUST00000015620.6
Prrt1
proline-rich transmembrane protein 1
chr19_+_42247544 1.351 ENSMUST00000122375.1
Golga7b
golgi autoantigen, golgin subfamily a, 7B
chr5_+_37050854 1.350 ENSMUST00000043794.4
Jakmip1
janus kinase and microtubule interacting protein 1
chr2_+_122147680 1.343 ENSMUST00000102476.4
B2m
beta-2 microglobulin
chr19_+_22139028 1.342 ENSMUST00000099569.2
ENSMUST00000087576.4
ENSMUST00000074770.5
Trpm3


transient receptor potential cation channel, subfamily M, member 3


chr5_-_148392810 1.323 ENSMUST00000138257.1
Slc7a1
solute carrier family 7 (cationic amino acid transporter, y+ system), member 1
chr12_-_69790660 1.322 ENSMUST00000021377.4
Cdkl1
cyclin-dependent kinase-like 1 (CDC2-related kinase)
chrX_-_135210672 1.322 ENSMUST00000033783.1
Tceal6
transcription elongation factor A (SII)-like 6
chr11_-_117873433 1.300 ENSMUST00000033230.7
Tha1
threonine aldolase 1
chr13_-_66852017 1.298 ENSMUST00000059329.6
Gm17449
predicted gene, 17449
chr1_-_184883218 1.297 ENSMUST00000048308.5
C130074G19Rik
RIKEN cDNA C130074G19 gene
chr7_+_141461728 1.291 ENSMUST00000167491.1
ENSMUST00000165194.1
Efcab4a

EF-hand calcium binding domain 4A

chr19_-_57314896 1.288 ENSMUST00000111524.1
Ablim1
actin-binding LIM protein 1
chr7_-_99695809 1.285 ENSMUST00000107086.2
Slco2b1
solute carrier organic anion transporter family, member 2b1
chr3_-_152982240 1.273 ENSMUST00000044278.5
St6galnac5
ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 5
chr7_+_3303503 1.233 ENSMUST00000100301.4
Prkcg
protein kinase C, gamma
chr18_+_31931470 1.216 ENSMUST00000025254.7
Lims2
LIM and senescent cell antigen like domains 2
chr8_+_23139064 1.211 ENSMUST00000033947.8
Ank1
ankyrin 1, erythroid
chr6_+_125552948 1.210 ENSMUST00000112254.1
ENSMUST00000112253.1
ENSMUST00000001995.7
Vwf


Von Willebrand factor homolog


chr11_+_87760533 1.207 ENSMUST00000039627.5
ENSMUST00000100644.3
Bzrap1

benzodiazepine receptor associated protein 1

chr7_+_46847128 1.200 ENSMUST00000005051.4
Ldha
lactate dehydrogenase A
chr2_+_130405256 1.181 ENSMUST00000110281.1
ENSMUST00000028898.3
1700020A23Rik

RIKEN cDNA 1700020A23 gene

chr10_-_75860250 1.178 ENSMUST00000038169.6
Mif
macrophage migration inhibitory factor
chr9_-_63711969 1.172 ENSMUST00000154323.1
Smad3
SMAD family member 3
chr8_-_105966038 1.158 ENSMUST00000116429.2
ENSMUST00000034370.9
Slc12a4

solute carrier family 12, member 4

chr2_-_10130638 1.150 ENSMUST00000042290.7
Itih2
inter-alpha trypsin inhibitor, heavy chain 2
chr2_+_156421048 1.147 ENSMUST00000109574.1
Epb4.1l1
erythrocyte protein band 4.1-like 1
chr12_-_84698769 1.109 ENSMUST00000095550.2
Syndig1l
synapse differentiation inducing 1 like
chr11_+_103103051 1.104 ENSMUST00000152971.1
Acbd4
acyl-Coenzyme A binding domain containing 4
chr19_+_44992127 1.103 ENSMUST00000179305.1
Sema4g
sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4G
chr11_+_119274856 1.094 ENSMUST00000150562.1
Gaa
glucosidase, alpha, acid
chr19_+_42255704 1.087 ENSMUST00000087123.5
Golga7b
golgi autoantigen, golgin subfamily a, 7B
chr11_-_108343917 1.082 ENSMUST00000059595.4
Prkca
protein kinase C, alpha
chr11_-_120041774 1.077 ENSMUST00000103019.1
Aatk
apoptosis-associated tyrosine kinase
chr4_+_3678108 1.058 ENSMUST00000041377.6
ENSMUST00000103010.3
Lyn

Yamaguchi sarcoma viral (v-yes-1) oncogene homolog

chr12_-_40038025 1.053 ENSMUST00000101472.3
Arl4a
ADP-ribosylation factor-like 4A
chr4_+_105789869 1.036 ENSMUST00000184254.1
Gm12728
predicted gene 12728
chr3_+_96181151 1.033 ENSMUST00000035371.8
Sv2a
synaptic vesicle glycoprotein 2 a
chr12_+_109549157 1.030 ENSMUST00000128458.1
ENSMUST00000150851.1
Meg3

maternally expressed 3

chr17_-_28486082 1.029 ENSMUST00000079413.3
Fkbp5
FK506 binding protein 5
chr5_-_113280572 1.022 ENSMUST00000112324.1
ENSMUST00000057209.5
Sgsm1

small G protein signaling modulator 1

chr4_+_152186179 1.017 ENSMUST00000030779.3
Acot7
acyl-CoA thioesterase 7
chr8_-_70487314 1.013 ENSMUST00000045286.7
Tmem59l
transmembrane protein 59-like
chr2_+_181680284 1.010 ENSMUST00000103042.3
Tcea2
transcription elongation factor A (SII), 2
chr18_+_74442551 0.988 ENSMUST00000121875.1
Myo5b
myosin VB
chr11_+_101246960 0.981 ENSMUST00000107282.3
Ramp2
receptor (calcitonin) activity modifying protein 2
chr7_+_49759100 0.972 ENSMUST00000085272.5
Htatip2
HIV-1 tat interactive protein 2, homolog (human)
chr18_+_67343564 0.971 ENSMUST00000025404.8
Cidea
cell death-inducing DNA fragmentation factor, alpha subunit-like effector A
chr18_+_74442500 0.963 ENSMUST00000074157.6
Myo5b
myosin VB
chr9_+_62858085 0.959 ENSMUST00000034777.6
ENSMUST00000163820.1
Calml4

calmodulin-like 4

chr13_+_45965211 0.949 ENSMUST00000038032.3
5033430I15Rik
RIKEN cDNA 5033430I15 gene
chr7_-_113369326 0.945 ENSMUST00000047091.7
ENSMUST00000119278.1
Btbd10

BTB (POZ) domain containing 10

chr8_-_36249292 0.934 ENSMUST00000065297.5
Lonrf1
LON peptidase N-terminal domain and ring finger 1
chr8_-_105289465 0.920 ENSMUST00000171788.1
ENSMUST00000014981.6
4931428F04Rik

RIKEN cDNA 4931428F04 gene

chr17_-_47692466 0.918 ENSMUST00000113300.1
Prickle4
prickle homolog 4 (Drosophila)
chr16_-_5222257 0.918 ENSMUST00000050160.4
AU021092
expressed sequence AU021092
chr4_+_136286061 0.912 ENSMUST00000069195.4
ENSMUST00000130658.1
Zfp46

zinc finger protein 46

chr10_+_116143881 0.911 ENSMUST00000105271.2
Ptprr
protein tyrosine phosphatase, receptor type, R
chr13_-_66227573 0.906 ENSMUST00000167981.2
Gm10772
predicted gene 10772
chr18_+_32938955 0.904 ENSMUST00000042868.4
Camk4
calcium/calmodulin-dependent protein kinase IV
chr18_-_12879973 0.900 ENSMUST00000119512.1
Osbpl1a
oxysterol binding protein-like 1A
chr7_+_128246953 0.897 ENSMUST00000167965.1
Tgfb1i1
transforming growth factor beta 1 induced transcript 1
chr2_+_140170641 0.893 ENSMUST00000044825.4
Ndufaf5
NADH dehydrogenase (ubiquinone) complex I, assembly factor 5
chr13_+_63282142 0.879 ENSMUST00000159152.1
2010111I01Rik
RIKEN cDNA 2010111I01 gene
chr4_+_99955715 0.866 ENSMUST00000102783.4
Pgm2
phosphoglucomutase 2
chr7_+_128246812 0.862 ENSMUST00000164710.1
ENSMUST00000070656.5
Tgfb1i1

transforming growth factor beta 1 induced transcript 1

chr4_+_134496996 0.854 ENSMUST00000095074.3
Paqr7
progestin and adipoQ receptor family member VII
chr15_+_99029866 0.852 ENSMUST00000058914.8
Tuba1c
tubulin, alpha 1C
chr3_-_59210881 0.849 ENSMUST00000040622.1
P2ry13
purinergic receptor P2Y, G-protein coupled 13
chr2_-_30801698 0.843 ENSMUST00000050003.8
1700001O22Rik
RIKEN cDNA 1700001O22 gene
chr17_+_25727726 0.841 ENSMUST00000047273.1
Rpusd1
RNA pseudouridylate synthase domain containing 1
chr6_+_4504814 0.839 ENSMUST00000141483.1
Col1a2
collagen, type I, alpha 2
chr14_-_6287250 0.820 ENSMUST00000170104.2
Gm3411
predicted gene 3411
chr11_-_69920581 0.819 ENSMUST00000108610.1
Eif5a
eukaryotic translation initiation factor 5A
chr10_-_80900749 0.810 ENSMUST00000020440.6
Timm13
translocase of inner mitochondrial membrane 13
chr7_+_99535652 0.800 ENSMUST00000032995.8
ENSMUST00000162404.1
Arrb1

arrestin, beta 1

chr10_-_9675163 0.795 ENSMUST00000100070.2
Samd5
sterile alpha motif domain containing 5
chr2_+_84826997 0.794 ENSMUST00000028470.3
Timm10
translocase of inner mitochondrial membrane 10
chr11_-_3722189 0.784 ENSMUST00000102950.3
ENSMUST00000101632.3
Osbp2

oxysterol binding protein 2

chr17_-_24644933 0.780 ENSMUST00000019684.5
Slc9a3r2
solute carrier family 9 (sodium/hydrogen exchanger), member 3 regulator 2
chr10_-_62143906 0.771 ENSMUST00000141724.1
ENSMUST00000150057.1
2010107G23Rik

RIKEN cDNA 2010107G23 gene

chr4_+_95579463 0.770 ENSMUST00000150830.1
ENSMUST00000134012.2
Fggy

FGGY carbohydrate kinase domain containing

chr2_-_152951688 0.770 ENSMUST00000109811.3
Dusp15
dual specificity phosphatase-like 15
chr6_+_135197977 0.767 ENSMUST00000111915.1
ENSMUST00000111916.1
8430419L09Rik

RIKEN cDNA 8430419L09 gene

chr7_-_126704179 0.763 ENSMUST00000106364.1
Coro1a
coronin, actin binding protein 1A
chr17_-_34031544 0.757 ENSMUST00000025186.8
Slc39a7
solute carrier family 39 (zinc transporter), member 7
chr2_+_180042496 0.756 ENSMUST00000041126.8
Ss18l1
synovial sarcoma translocation gene on chromosome 18-like 1
chr4_-_155774563 0.756 ENSMUST00000042196.3
Vwa1
von Willebrand factor A domain containing 1
chr15_+_80097866 0.751 ENSMUST00000143928.1
Syngr1
synaptogyrin 1
chr13_-_24937585 0.746 ENSMUST00000037615.6
Aldh5a1
aldhehyde dehydrogenase family 5, subfamily A1
chr2_+_4559742 0.744 ENSMUST00000176828.1
Frmd4a
FERM domain containing 4A
chr11_-_106779483 0.740 ENSMUST00000021060.5
Polg2
polymerase (DNA directed), gamma 2, accessory subunit
chr6_+_82052307 0.739 ENSMUST00000149023.1
Eva1a
eva-1 homolog A (C. elegans)
chrX_+_136666375 0.732 ENSMUST00000060904.4
ENSMUST00000113100.1
ENSMUST00000128040.1
Tceal3


transcription elongation factor A (SII)-like 3


chr5_-_77095225 0.723 ENSMUST00000120827.2
ENSMUST00000113453.2
Hopx

HOP homeobox

chr15_-_82047579 0.719 ENSMUST00000166578.1
ENSMUST00000080622.7
Nhp2l1

NHP2 non-histone chromosome protein 2-like 1 (S. cerevisiae)

chr10_-_61383523 0.719 ENSMUST00000020289.8
Pald1
phosphatase domain containing, paladin 1
chr19_-_6909599 0.718 ENSMUST00000173091.1
Prdx5
peroxiredoxin 5
chr2_+_105904629 0.715 ENSMUST00000037499.5
Immp1l
IMP1 inner mitochondrial membrane peptidase-like (S. cerevisiae)
chr11_-_73177002 0.712 ENSMUST00000108480.1
ENSMUST00000054952.3
Emc6

ER membrane protein complex subunit 6

chr11_+_69059750 0.709 ENSMUST00000051888.2
2310047M10Rik
RIKEN cDNA 2310047M10 gene
chr7_-_142656018 0.708 ENSMUST00000178921.1
Igf2
insulin-like growth factor 2
chr1_-_33757711 0.697 ENSMUST00000044691.7
Bag2
BCL2-associated athanogene 2
chr13_-_92483996 0.697 ENSMUST00000040106.7
Fam151b
family with sequence similarity 151, member B
chr18_-_37997543 0.696 ENSMUST00000042944.7
Arap3
ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 3
chr11_-_3863895 0.694 ENSMUST00000070552.7
Osbp2
oxysterol binding protein 2
chr10_-_81496329 0.691 ENSMUST00000020463.7
Ncln
nicalin homolog (zebrafish)
chr18_+_74065102 0.683 ENSMUST00000066583.1
Gm9925
predicted gene 9925
chrX_+_99042581 0.682 ENSMUST00000036606.7
Stard8
START domain containing 8
chr2_+_118111876 0.676 ENSMUST00000039559.8
Thbs1
thrombospondin 1
chr18_+_86394952 0.675 ENSMUST00000058829.2
Neto1
neuropilin (NRP) and tolloid (TLL)-like 1
chr7_+_126823287 0.675 ENSMUST00000079423.5
Fam57b
family with sequence similarity 57, member B
chr11_-_102447647 0.673 ENSMUST00000049057.4
Fam171a2
family with sequence similarity 171, member A2
chr18_+_80255227 0.670 ENSMUST00000123750.1
Pqlc1
PQ loop repeat containing 1
chr4_+_137862237 0.670 ENSMUST00000102518.3
Ece1
endothelin converting enzyme 1
chr12_+_75308308 0.669 ENSMUST00000118602.1
ENSMUST00000118966.1
ENSMUST00000055390.5
Rhoj


ras homolog gene family, member J


chrX_+_42526585 0.667 ENSMUST00000101619.3
Gm10483
predicted gene 10483
chr15_+_80287234 0.664 ENSMUST00000160424.1
Cacna1i
calcium channel, voltage-dependent, alpha 1I subunit
chr19_-_19111181 0.661 ENSMUST00000112832.1
Rorb
RAR-related orphan receptor beta
chr4_-_139131058 0.660 ENSMUST00000143971.1
Minos1
mitochondrial inner membrane organizing system 1
chr3_-_9004686 0.657 ENSMUST00000120143.1
Tpd52
tumor protein D52
chr15_-_89128634 0.656 ENSMUST00000082197.5
Hdac10
histone deacetylase 10
chr8_+_94179089 0.655 ENSMUST00000034215.6
Mt1
metallothionein 1
chr8_+_70315759 0.654 ENSMUST00000165819.2
ENSMUST00000140239.1
Gdf1
Cers1
growth differentiation factor 1
ceramide synthase 1
chr10_-_85185003 0.653 ENSMUST00000020227.9
Cry1
cryptochrome 1 (photolyase-like)
chr17_+_83706137 0.652 ENSMUST00000112350.1
ENSMUST00000112349.2
ENSMUST00000112352.3
Mta3


metastasis associated 3


chr5_-_92278155 0.644 ENSMUST00000159345.1
ENSMUST00000113102.3
Naaa

N-acylethanolamine acid amidase

chr17_-_12960729 0.638 ENSMUST00000007005.7
Acat2
acetyl-Coenzyme A acetyltransferase 2
chr9_+_65214690 0.633 ENSMUST00000069000.7
Parp16
poly (ADP-ribose) polymerase family, member 16
chr7_-_3693523 0.632 ENSMUST00000038608.7
Mboat7
membrane bound O-acyltransferase domain containing 7
chr3_+_62419668 0.627 ENSMUST00000161057.1
Arhgef26
Rho guanine nucleotide exchange factor (GEF) 26
chr10_+_77978524 0.627 ENSMUST00000105397.3
ENSMUST00000105398.1
1810043G02Rik

RIKEN cDNA 1810043G02 gene

chr2_-_152951547 0.618 ENSMUST00000037715.6
Dusp15
dual specificity phosphatase-like 15
chr18_+_23752333 0.613 ENSMUST00000170802.1
ENSMUST00000155708.1
ENSMUST00000118826.2
Mapre2


microtubule-associated protein, RP/EB family, member 2


chr17_-_65613521 0.612 ENSMUST00000024897.8
Vapa
vesicle-associated membrane protein, associated protein A
chr3_+_95217417 0.611 ENSMUST00000181819.1
Gm16740
predicted gene, 16740
chr4_+_155831630 0.610 ENSMUST00000105592.1
ENSMUST00000105591.1
Aurkaip1

aurora kinase A interacting protein 1

chr7_+_99267428 0.606 ENSMUST00000068973.4
ENSMUST00000122101.1
Map6

microtubule-associated protein 6

chr2_+_32741452 0.604 ENSMUST00000131101.1
Sh2d3c
SH2 domain containing 3C
chr3_-_9004472 0.601 ENSMUST00000091355.5
ENSMUST00000134788.1
Tpd52

tumor protein D52

chr15_-_75982442 0.597 ENSMUST00000183130.1
ENSMUST00000182172.1
Ccdc166

coiled-coil domain containing 166

chr3_+_137341103 0.593 ENSMUST00000119475.1
Emcn
endomucin
chr9_-_21963568 0.592 ENSMUST00000006397.5
Epor
erythropoietin receptor
chr2_+_136891501 0.592 ENSMUST00000141463.1
Slx4ip
SLX4 interacting protein
chr6_-_85069449 0.589 ENSMUST00000160783.1
ENSMUST00000160197.1
Exoc6b

exocyst complex component 6B

chr8_+_69791163 0.577 ENSMUST00000034326.6
Atp13a1
ATPase type 13A1
chr8_-_83955205 0.575 ENSMUST00000098595.2
Gm10644
predicted gene 10644
chr4_+_42240639 0.575 ENSMUST00000117202.2
Gm10600
predicted gene 10600
chr3_-_9004422 0.573 ENSMUST00000063496.7
Tpd52
tumor protein D52
chr9_+_107587711 0.570 ENSMUST00000010192.5
Ifrd2
interferon-related developmental regulator 2
chr7_+_28440927 0.570 ENSMUST00000078845.6
Gmfg
glia maturation factor, gamma
chr1_-_75180349 0.568 ENSMUST00000027396.8
Abcb6
ATP-binding cassette, sub-family B (MDR/TAP), member 6
chr2_-_34799618 0.565 ENSMUST00000113086.2
ENSMUST00000118108.1
Rabepk

Rab9 effector protein with kelch motifs

chr11_-_59163281 0.564 ENSMUST00000069631.2
Iba57
IBA57, iron-sulfur cluster assembly homolog (S. cerevisiae)

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
1.0 3.1 GO:0001543 ovarian follicle rupture(GO:0001543)
0.9 3.6 GO:1900533 medium-chain fatty-acyl-CoA catabolic process(GO:0036114) long-chain fatty-acyl-CoA catabolic process(GO:0036116) palmitic acid metabolic process(GO:1900533) palmitic acid biosynthetic process(GO:1900535)
0.8 2.3 GO:1902256 apoptotic process involved in outflow tract morphogenesis(GO:0003275) regulation of apoptotic process involved in outflow tract morphogenesis(GO:1902256) response to chemokine(GO:1990868) cellular response to chemokine(GO:1990869)
0.7 3.6 GO:0002024 diet induced thermogenesis(GO:0002024)
0.7 1.3 GO:0034759 regulation of iron ion transport(GO:0034756) regulation of iron ion transmembrane transport(GO:0034759)
0.6 2.6 GO:1901475 pyruvate transmembrane transport(GO:1901475)
0.6 1.9 GO:1903630 regulation of aminoacyl-tRNA ligase activity(GO:1903630) positive regulation of aminoacyl-tRNA ligase activity(GO:1903632)
0.6 1.9 GO:0051892 negative regulation of cardioblast differentiation(GO:0051892)
0.6 1.7 GO:0051542 elastin biosynthetic process(GO:0051542)
0.6 1.7 GO:0035585 calcium-mediated signaling using extracellular calcium source(GO:0035585)
0.5 2.2 GO:0019276 UDP-N-acetylgalactosamine metabolic process(GO:0019276)
0.5 2.2 GO:0035021 negative regulation of Rac protein signal transduction(GO:0035021)
0.5 1.6 GO:0014738 regulation of muscle hyperplasia(GO:0014738) muscle hyperplasia(GO:0014900)
0.5 1.5 GO:1900149 positive regulation of Schwann cell migration(GO:1900149)
0.5 1.5 GO:0002765 immune response-inhibiting signal transduction(GO:0002765)
0.4 1.8 GO:0001550 ovarian cumulus expansion(GO:0001550) fused antrum stage(GO:0048165)
0.4 1.3 GO:0006566 threonine metabolic process(GO:0006566)
0.4 1.6 GO:0014846 esophagus smooth muscle contraction(GO:0014846)
0.4 1.2 GO:0002035 brain renin-angiotensin system(GO:0002035)
0.4 1.2 GO:0044413 regulation of lung blood pressure(GO:0014916) evasion or tolerance of host defenses by virus(GO:0019049) positive regulation of transforming growth factor beta3 production(GO:0032916) avoidance of host defenses(GO:0044413) evasion or tolerance of host defenses(GO:0044415) avoidance of defenses of other organism involved in symbiotic interaction(GO:0051832) evasion or tolerance of defenses of other organism involved in symbiotic interaction(GO:0051834)
0.4 1.1 GO:0043181 vacuolar sequestering(GO:0043181)
0.4 1.1 GO:0010360 desmosome assembly(GO:0002159) negative regulation of anion channel activity(GO:0010360)
0.4 1.4 GO:0061526 acetylcholine secretion, neurotransmission(GO:0014055) regulation of acetylcholine secretion, neurotransmission(GO:0014056) acetylcholine secretion(GO:0061526)
0.3 1.4 GO:0010986 positive regulation of lipoprotein particle clearance(GO:0010986)
0.3 0.7 GO:0002578 negative regulation of antigen processing and presentation(GO:0002578)
0.3 2.0 GO:0032439 endosome localization(GO:0032439)
0.3 1.0 GO:0046022 regulation of transcription from RNA polymerase II promoter, mitotic(GO:0046021) positive regulation of transcription from RNA polymerase II promoter during mitosis(GO:0046022)
0.3 1.0 GO:1900122 positive regulation of receptor binding(GO:1900122)
0.3 1.6 GO:0045039 protein import into mitochondrial inner membrane(GO:0045039)
0.3 1.6 GO:0070305 response to cGMP(GO:0070305) cellular response to cGMP(GO:0071321)
0.3 1.6 GO:0019659 fermentation(GO:0006113) lactate biosynthetic process from pyruvate(GO:0019244) glucose catabolic process to lactate(GO:0019659) glycolytic fermentation(GO:0019660) glucose catabolic process to lactate via pyruvate(GO:0019661)
0.3 2.6 GO:0061002 negative regulation of dendritic spine morphogenesis(GO:0061002)
0.2 0.7 GO:0006083 acetate metabolic process(GO:0006083)
0.2 1.2 GO:0032423 regulation of mismatch repair(GO:0032423)
0.2 0.7 GO:0060785 regulation of apoptosis involved in tissue homeostasis(GO:0060785)
0.2 1.2 GO:0010273 detoxification of copper ion(GO:0010273) stress response to copper ion(GO:1990169)
0.2 0.9 GO:0038128 ERBB2 signaling pathway(GO:0038128)
0.2 0.7 GO:2000312 regulation of kainate selective glutamate receptor activity(GO:2000312)
0.2 2.4 GO:0018230 peptidyl-L-cysteine S-palmitoylation(GO:0018230) peptidyl-S-diacylglycerol-L-cysteine biosynthetic process from peptidyl-cysteine(GO:0018231)
0.2 0.7 GO:0072720 cellular response to UV-A(GO:0071492) response to dithiothreitol(GO:0072720)
0.2 0.7 GO:2000850 negative regulation of corticosteroid hormone secretion(GO:2000847) negative regulation of glucocorticoid secretion(GO:2000850)
0.2 0.6 GO:0030300 regulation of intestinal cholesterol absorption(GO:0030300)
0.2 1.4 GO:0030579 ubiquitin-dependent SMAD protein catabolic process(GO:0030579)
0.2 2.2 GO:0060347 heart trabecula formation(GO:0060347)
0.2 0.6 GO:0015886 heme transport(GO:0015886)
0.2 0.8 GO:0010890 positive regulation of sequestering of triglyceride(GO:0010890)
0.2 1.8 GO:0046959 habituation(GO:0046959)
0.2 0.5 GO:0051030 snRNA transport(GO:0051030)
0.2 0.5 GO:0010814 substance P catabolic process(GO:0010814) calcitonin catabolic process(GO:0010816) endothelin maturation(GO:0034959)
0.2 0.5 GO:0006597 spermine biosynthetic process(GO:0006597)
0.2 0.5 GO:0061744 motor behavior(GO:0061744)
0.2 1.0 GO:0097646 calcitonin family receptor signaling pathway(GO:0097646) amylin receptor signaling pathway(GO:0097647)
0.2 0.5 GO:0009174 UMP biosynthetic process(GO:0006222) pyrimidine ribonucleoside monophosphate metabolic process(GO:0009173) pyrimidine ribonucleoside monophosphate biosynthetic process(GO:0009174) UMP metabolic process(GO:0046049)
0.2 0.8 GO:0042699 follicle-stimulating hormone signaling pathway(GO:0042699)
0.2 0.6 GO:0070213 protein auto-ADP-ribosylation(GO:0070213)
0.2 0.5 GO:0002940 tRNA N2-guanine methylation(GO:0002940)
0.2 1.1 GO:0070127 tRNA aminoacylation for mitochondrial protein translation(GO:0070127)
0.1 0.4 GO:0072204 cell-cell signaling involved in kidney development(GO:0060995) Wnt signaling pathway involved in kidney development(GO:0061289) canonical Wnt signaling pathway involved in metanephric kidney development(GO:0061290) cell-cell signaling involved in metanephros development(GO:0072204)
0.1 0.4 GO:0009051 pentose-phosphate shunt, oxidative branch(GO:0009051)
0.1 0.4 GO:0060672 epithelial cell differentiation involved in embryonic placenta development(GO:0060671) epithelial cell morphogenesis involved in placental branching(GO:0060672)
0.1 0.4 GO:2000393 negative regulation of lamellipodium morphogenesis(GO:2000393)
0.1 0.8 GO:0006452 translational frameshifting(GO:0006452) positive regulation of translational termination(GO:0045905)
0.1 0.1 GO:0036482 neuron intrinsic apoptotic signaling pathway in response to hydrogen peroxide(GO:0036482) positive regulation of mitochondrial electron transport, NADH to ubiquinone(GO:1902958) regulation of hydrogen peroxide-induced neuron intrinsic apoptotic signaling pathway(GO:1903383) negative regulation of hydrogen peroxide-induced neuron intrinsic apoptotic signaling pathway(GO:1903384)
0.1 1.8 GO:0007190 activation of adenylate cyclase activity(GO:0007190)
0.1 0.8 GO:0032796 uropod organization(GO:0032796)
0.1 0.5 GO:0072531 pyrimidine-containing compound transmembrane transport(GO:0072531)
0.1 0.5 GO:0009597 detection of virus(GO:0009597)
0.1 1.8 GO:0009312 oligosaccharide biosynthetic process(GO:0009312)
0.1 0.4 GO:0048611 ectodermal digestive tract development(GO:0007439) embryonic ectodermal digestive tract development(GO:0048611)
0.1 1.3 GO:0015721 bile acid and bile salt transport(GO:0015721)
0.1 0.4 GO:0006751 glutathione catabolic process(GO:0006751)
0.1 0.5 GO:0070164 negative regulation of adiponectin secretion(GO:0070164)
0.1 0.9 GO:0019388 galactose catabolic process(GO:0019388)
0.1 0.3 GO:0006532 aspartate biosynthetic process(GO:0006532)
0.1 1.1 GO:0032482 Rab protein signal transduction(GO:0032482)
0.1 0.6 GO:0034316 negative regulation of Arp2/3 complex-mediated actin nucleation(GO:0034316) negative regulation of actin nucleation(GO:0051126)
0.1 0.7 GO:0046549 retinal cone cell development(GO:0046549)
0.1 0.6 GO:0006172 ADP biosynthetic process(GO:0006172)
0.1 1.4 GO:0015809 arginine transport(GO:0015809)
0.1 0.7 GO:0034975 protein folding in endoplasmic reticulum(GO:0034975)
0.1 0.5 GO:0042795 snRNA transcription from RNA polymerase II promoter(GO:0042795)
0.1 1.0 GO:0014052 regulation of gamma-aminobutyric acid secretion(GO:0014052)
0.1 0.3 GO:0016132 brassinosteroid metabolic process(GO:0016131) brassinosteroid biosynthetic process(GO:0016132)
0.1 0.8 GO:0031118 rRNA pseudouridine synthesis(GO:0031118)
0.1 1.1 GO:0033623 regulation of integrin activation(GO:0033623)
0.1 0.6 GO:0018401 peptidyl-proline hydroxylation to 4-hydroxy-L-proline(GO:0018401)
0.1 0.7 GO:2000467 positive regulation of glycogen (starch) synthase activity(GO:2000467)
0.1 0.8 GO:0007194 negative regulation of adenylate cyclase activity(GO:0007194)
0.1 0.8 GO:0019321 pentose metabolic process(GO:0019321)
0.1 0.6 GO:0044791 modulation by host of viral release from host cell(GO:0044789) positive regulation by host of viral release from host cell(GO:0044791) positive regulation by host of viral genome replication(GO:0044829)
0.1 0.7 GO:0034983 peptidyl-lysine deacetylation(GO:0034983)
0.1 0.6 GO:2000491 positive regulation of hepatic stellate cell activation(GO:2000491)
0.1 3.0 GO:0033014 tetrapyrrole biosynthetic process(GO:0033014)
0.1 0.8 GO:0043589 skin morphogenesis(GO:0043589)
0.1 0.6 GO:0097178 ruffle assembly(GO:0097178)
0.1 0.4 GO:0098707 ferrous iron import(GO:0070627) ferrous iron import into cell(GO:0097460) ferrous iron import across plasma membrane(GO:0098707)
0.1 2.0 GO:0010738 regulation of protein kinase A signaling(GO:0010738)
0.1 0.5 GO:0035845 photoreceptor cell outer segment organization(GO:0035845)
0.1 0.9 GO:2000009 negative regulation of protein localization to cell surface(GO:2000009)
0.1 0.8 GO:0060294 cilium movement involved in cell motility(GO:0060294)
0.1 1.2 GO:0071577 zinc II ion transmembrane transport(GO:0071577)
0.1 0.1 GO:0071603 endothelial cell-cell adhesion(GO:0071603)
0.1 0.3 GO:0000957 mitochondrial RNA catabolic process(GO:0000957) regulation of mitochondrial RNA catabolic process(GO:0000960)
0.1 0.8 GO:0048266 behavioral response to pain(GO:0048266)
0.1 0.8 GO:0006857 oligopeptide transport(GO:0006857)
0.1 0.2 GO:0098928 presynaptic signal transduction(GO:0098928) presynapse to nucleus signaling pathway(GO:0099526)
0.1 0.2 GO:0015786 UDP-glucose transport(GO:0015786)
0.1 0.4 GO:0006627 protein processing involved in protein targeting to mitochondrion(GO:0006627)
0.1 0.2 GO:2000767 positive regulation of cytoplasmic translation(GO:2000767)
0.1 0.5 GO:1901838 positive regulation of transcription of nuclear large rRNA transcript from RNA polymerase I promoter(GO:1901838)
0.1 0.2 GO:0033563 dorsal/ventral axon guidance(GO:0033563)
0.1 0.9 GO:0018195 peptidyl-arginine modification(GO:0018195)
0.1 0.6 GO:0061032 visceral serous pericardium development(GO:0061032)
0.1 0.3 GO:0001574 ganglioside biosynthetic process(GO:0001574)
0.1 0.2 GO:0090204 protein localization to nuclear pore(GO:0090204) positive regulation of calcium-transporting ATPase activity(GO:1901896)
0.1 1.0 GO:0006744 ubiquinone biosynthetic process(GO:0006744)
0.1 0.3 GO:0052695 cellular glucuronidation(GO:0052695)
0.1 0.7 GO:0061299 retina vasculature morphogenesis in camera-type eye(GO:0061299)
0.1 0.2 GO:1900020 prolactin secretion(GO:0070459) regulation of protein kinase C activity(GO:1900019) positive regulation of protein kinase C activity(GO:1900020)
0.1 0.3 GO:0075525 viral translational termination-reinitiation(GO:0075525)
0.1 0.4 GO:0035729 cellular response to hepatocyte growth factor stimulus(GO:0035729)
0.1 0.2 GO:1902268 negative regulation of polyamine transmembrane transport(GO:1902268)
0.1 0.5 GO:0050774 negative regulation of dendrite morphogenesis(GO:0050774)
0.0 0.2 GO:0003376 sphingosine-1-phosphate signaling pathway(GO:0003376) sphingolipid mediated signaling pathway(GO:0090520)
0.0 0.4 GO:0071340 skeletal muscle acetylcholine-gated channel clustering(GO:0071340)
0.0 0.2 GO:0006742 NADP catabolic process(GO:0006742) pyridine nucleotide catabolic process(GO:0019364)
0.0 1.0 GO:0008340 determination of adult lifespan(GO:0008340)
0.0 1.2 GO:2000178 negative regulation of neural precursor cell proliferation(GO:2000178)
0.0 0.4 GO:0090336 positive regulation of brown fat cell differentiation(GO:0090336)
0.0 0.1 GO:1901165 regulation of MDA-5 signaling pathway(GO:0039533) positive regulation of trophoblast cell migration(GO:1901165) positive regulation of dendritic cell chemotaxis(GO:2000510)
0.0 0.1 GO:0036166 phenotypic switching(GO:0036166)
0.0 0.2 GO:0007250 activation of NF-kappaB-inducing kinase activity(GO:0007250)
0.0 0.2 GO:0051684 maintenance of Golgi location(GO:0051684)
0.0 1.2 GO:0030212 hyaluronan metabolic process(GO:0030212)
0.0 0.6 GO:0035814 negative regulation of renal sodium excretion(GO:0035814)
0.0 0.3 GO:0035878 nail development(GO:0035878)
0.0 3.5 GO:0030032 lamellipodium assembly(GO:0030032)
0.0 1.0 GO:0034314 Arp2/3 complex-mediated actin nucleation(GO:0034314)
0.0 2.3 GO:0010501 RNA secondary structure unwinding(GO:0010501)
0.0 0.8 GO:0051131 chaperone-mediated protein complex assembly(GO:0051131)
0.0 0.2 GO:0000379 tRNA-type intron splice site recognition and cleavage(GO:0000379)
0.0 0.3 GO:0032790 ribosome disassembly(GO:0032790)
0.0 1.0 GO:0000413 protein peptidyl-prolyl isomerization(GO:0000413)
0.0 0.4 GO:0008063 Toll signaling pathway(GO:0008063)
0.0 0.6 GO:0045792 negative regulation of cell size(GO:0045792)
0.0 0.1 GO:0072553 terminal button organization(GO:0072553)
0.0 0.4 GO:1900119 positive regulation of execution phase of apoptosis(GO:1900119)
0.0 0.3 GO:1901029 negative regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway(GO:1901029)
0.0 0.2 GO:0002718 regulation of cytokine production involved in immune response(GO:0002718)
0.0 0.9 GO:0044342 type B pancreatic cell proliferation(GO:0044342)
0.0 0.6 GO:0043248 proteasome assembly(GO:0043248)
0.0 0.8 GO:0014067 negative regulation of phosphatidylinositol 3-kinase signaling(GO:0014067)
0.0 0.1 GO:1902626 assembly of large subunit precursor of preribosome(GO:1902626)
0.0 0.9 GO:0046827 positive regulation of protein export from nucleus(GO:0046827)
0.0 0.3 GO:0006729 tetrahydrobiopterin biosynthetic process(GO:0006729) tetrahydrobiopterin metabolic process(GO:0046146)
0.0 0.3 GO:0032020 ISG15-protein conjugation(GO:0032020)
0.0 0.3 GO:1905146 lysosomal lumen acidification(GO:0007042) lysosomal protein catabolic process(GO:1905146)
0.0 0.1 GO:0002636 positive regulation of germinal center formation(GO:0002636)
0.0 0.6 GO:0048172 regulation of short-term neuronal synaptic plasticity(GO:0048172)
0.0 0.5 GO:0030150 protein import into mitochondrial matrix(GO:0030150)
0.0 0.6 GO:0021819 layer formation in cerebral cortex(GO:0021819)
0.0 0.3 GO:0035269 protein O-linked mannosylation(GO:0035269)
0.0 0.2 GO:0002176 male germ cell proliferation(GO:0002176)
0.0 0.3 GO:2000671 regulation of motor neuron apoptotic process(GO:2000671)
0.0 0.3 GO:0033005 positive regulation of mast cell activation(GO:0033005) positive regulation of mast cell activation involved in immune response(GO:0033008) positive regulation of mast cell degranulation(GO:0043306)
0.0 0.2 GO:0001955 blood vessel maturation(GO:0001955)
0.0 0.7 GO:0045956 sleep(GO:0030431) positive regulation of calcium ion-dependent exocytosis(GO:0045956)
0.0 0.1 GO:0097026 myeloid dendritic cell chemotaxis(GO:0002408) dendritic cell dendrite assembly(GO:0097026) mature conventional dendritic cell differentiation(GO:0097029)
0.0 0.2 GO:0060050 positive regulation of protein glycosylation(GO:0060050)
0.0 1.4 GO:0048713 regulation of oligodendrocyte differentiation(GO:0048713)
0.0 0.8 GO:0071480 cellular response to gamma radiation(GO:0071480)
0.0 0.2 GO:0000056 ribosomal small subunit export from nucleus(GO:0000056)
0.0 0.1 GO:0031087 deadenylation-independent decapping of nuclear-transcribed mRNA(GO:0031087)
0.0 0.1 GO:0019858 cytosine metabolic process(GO:0019858)
0.0 0.2 GO:0032261 purine nucleotide salvage(GO:0032261) IMP salvage(GO:0032264)
0.0 0.3 GO:2000480 negative regulation of cAMP-dependent protein kinase activity(GO:2000480)
0.0 0.4 GO:0016486 peptide hormone processing(GO:0016486)
0.0 1.1 GO:0032729 positive regulation of interferon-gamma production(GO:0032729)
0.0 0.1 GO:0014063 negative regulation of serotonin secretion(GO:0014063)
0.0 0.9 GO:0090162 establishment of epithelial cell polarity(GO:0090162)
0.0 0.3 GO:0071260 cellular response to mechanical stimulus(GO:0071260)
0.0 0.7 GO:0006904 vesicle docking involved in exocytosis(GO:0006904)
0.0 0.2 GO:0060340 positive regulation of type I interferon-mediated signaling pathway(GO:0060340)
0.0 0.2 GO:0071786 endoplasmic reticulum tubular network organization(GO:0071786)
0.0 0.2 GO:0034694 response to prostaglandin(GO:0034694) response to prostaglandin E(GO:0034695) indole-containing compound biosynthetic process(GO:0042435)
0.0 0.4 GO:0035455 response to interferon-alpha(GO:0035455)
0.0 0.2 GO:0031848 protection from non-homologous end joining at telomere(GO:0031848)
0.0 0.6 GO:0015985 energy coupled proton transport, down electrochemical gradient(GO:0015985) ATP synthesis coupled proton transport(GO:0015986)
0.0 0.5 GO:0048268 clathrin coat assembly(GO:0048268)
0.0 0.1 GO:0019695 choline metabolic process(GO:0019695)
0.0 0.3 GO:0051292 nuclear pore complex assembly(GO:0051292)
0.0 0.1 GO:0033631 cell-cell adhesion mediated by integrin(GO:0033631)
0.0 0.7 GO:0032418 lysosome localization(GO:0032418)
0.0 0.4 GO:1990126 retrograde transport, endosome to plasma membrane(GO:1990126)
0.0 0.7 GO:0097031 NADH dehydrogenase complex assembly(GO:0010257) mitochondrial respiratory chain complex I assembly(GO:0032981) mitochondrial respiratory chain complex I biogenesis(GO:0097031)
0.0 0.3 GO:0051447 negative regulation of meiotic cell cycle(GO:0051447)
0.0 0.1 GO:0006420 arginyl-tRNA aminoacylation(GO:0006420)
0.0 1.2 GO:0050810 regulation of steroid biosynthetic process(GO:0050810)
0.0 0.7 GO:0030317 sperm motility(GO:0030317)
0.0 0.1 GO:1904715 negative regulation of chaperone-mediated autophagy(GO:1904715)
0.0 0.2 GO:0031274 positive regulation of pseudopodium assembly(GO:0031274)
0.0 0.1 GO:0045003 DNA recombinase assembly(GO:0000730) double-strand break repair via synthesis-dependent strand annealing(GO:0045003)
0.0 0.4 GO:0048791 calcium ion-regulated exocytosis of neurotransmitter(GO:0048791)
0.0 0.0 GO:1901052 sarcosine metabolic process(GO:1901052) sarcosine catabolic process(GO:1901053)
0.0 0.5 GO:0045214 sarcomere organization(GO:0045214)
0.0 0.6 GO:0031648 protein destabilization(GO:0031648)
0.0 0.1 GO:0006488 dolichol-linked oligosaccharide biosynthetic process(GO:0006488)
0.0 0.1 GO:0001867 complement activation, lectin pathway(GO:0001867)
0.0 0.2 GO:0045063 T-helper 1 cell differentiation(GO:0045063)
0.0 0.8 GO:0050775 positive regulation of dendrite morphogenesis(GO:0050775)
0.0 0.1 GO:0002478 antigen processing and presentation of exogenous peptide antigen(GO:0002478)
0.0 0.2 GO:0032927 positive regulation of activin receptor signaling pathway(GO:0032927)
0.0 0.0 GO:1903048 regulation of acetylcholine-gated cation channel activity(GO:1903048)
0.0 0.1 GO:0030644 cellular chloride ion homeostasis(GO:0030644)
0.0 0.2 GO:0001890 placenta development(GO:0001890)
0.0 0.4 GO:1903146 regulation of mitophagy(GO:1903146)
0.0 1.9 GO:0060828 regulation of canonical Wnt signaling pathway(GO:0060828)
0.0 0.4 GO:0002548 monocyte chemotaxis(GO:0002548)
0.0 0.4 GO:0006418 tRNA aminoacylation for protein translation(GO:0006418)
0.0 0.5 GO:0000184 nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:0000184)
0.0 0.1 GO:0018002 N-terminal peptidyl-serine acetylation(GO:0017198) N-terminal peptidyl-glutamic acid acetylation(GO:0018002) peptidyl-serine acetylation(GO:0030920)
0.0 0.4 GO:0045471 response to ethanol(GO:0045471)
0.0 0.1 GO:0006390 transcription from mitochondrial promoter(GO:0006390)
0.0 0.3 GO:0097009 energy homeostasis(GO:0097009)
0.0 0.2 GO:1903779 regulation of cardiac conduction(GO:1903779)
0.0 0.1 GO:1990564 protein polyufmylation(GO:1990564) protein K69-linked ufmylation(GO:1990592)
0.0 0.1 GO:0035024 negative regulation of Rho protein signal transduction(GO:0035024)
0.0 0.1 GO:2000821 regulation of grooming behavior(GO:2000821)
0.0 0.9 GO:0010811 positive regulation of cell-substrate adhesion(GO:0010811)
0.0 0.1 GO:0045292 mRNA cis splicing, via spliceosome(GO:0045292)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 1.6 GO:0098855 HCN channel complex(GO:0098855)
0.5 1.5 GO:0072534 perineuronal net(GO:0072534)
0.4 1.7 GO:0031095 platelet dense tubular network membrane(GO:0031095)
0.4 1.9 GO:0042719 mitochondrial intermembrane space protein transporter complex(GO:0042719)
0.4 1.1 GO:0034666 integrin alpha2-beta1 complex(GO:0034666)
0.3 1.7 GO:0033093 Weibel-Palade body(GO:0033093)
0.3 2.0 GO:0045179 apical cortex(GO:0045179)
0.3 0.8 GO:0005584 collagen type I trimer(GO:0005584)
0.2 0.7 GO:0042720 mitochondrial inner membrane peptidase complex(GO:0042720)
0.2 1.2 GO:0071144 SMAD2-SMAD3 protein complex(GO:0071144)
0.2 0.7 GO:0005577 fibrinogen complex(GO:0005577)
0.2 2.4 GO:0002178 palmitoyltransferase complex(GO:0002178)
0.2 1.0 GO:1903440 calcitonin family receptor complex(GO:1903439) amylin receptor complex(GO:1903440)
0.2 1.7 GO:0061574 ASAP complex(GO:0061574)
0.2 5.1 GO:0031430 M band(GO:0031430)
0.2 0.5 GO:0005927 muscle tendon junction(GO:0005927)
0.2 0.7 GO:1903349 omegasome membrane(GO:1903349)
0.2 1.8 GO:1990712 HFE-transferrin receptor complex(GO:1990712)
0.2 2.4 GO:0032580 Golgi cisterna membrane(GO:0032580)
0.2 2.5 GO:0017101 aminoacyl-tRNA synthetase multienzyme complex(GO:0017101)
0.2 0.6 GO:0031983 vesicle lumen(GO:0031983)
0.1 0.9 GO:0031314 extrinsic component of mitochondrial inner membrane(GO:0031314)
0.1 0.5 GO:1902636 kinociliary basal body(GO:1902636)
0.1 1.8 GO:0017146 NMDA selective glutamate receptor complex(GO:0017146)
0.1 1.9 GO:0008074 guanylate cyclase complex, soluble(GO:0008074)
0.1 0.4 GO:0014802 terminal cisterna(GO:0014802)
0.1 0.3 GO:0016222 procollagen-proline 4-dioxygenase complex(GO:0016222)
0.1 1.2 GO:0005614 interstitial matrix(GO:0005614)
0.1 0.8 GO:0005642 annulate lamellae(GO:0005642)
0.1 0.7 GO:0005742 mitochondrial outer membrane translocase complex(GO:0005742)
0.1 0.2 GO:0034457 Mpp10 complex(GO:0034457)
0.1 0.3 GO:0033185 dolichol-phosphate-mannose synthase complex(GO:0033185)
0.1 0.4 GO:1990745 EARP complex(GO:1990745)
0.1 0.8 GO:0032426 stereocilium tip(GO:0032426)
0.1 0.4 GO:0005853 eukaryotic translation elongation factor 1 complex(GO:0005853)
0.1 0.6 GO:0001520 outer dense fiber(GO:0001520)
0.1 0.4 GO:0000812 Swr1 complex(GO:0000812)
0.1 0.7 GO:0005885 Arp2/3 protein complex(GO:0005885)
0.1 0.9 GO:0031143 pseudopodium(GO:0031143)
0.1 0.2 GO:0031510 SUMO activating enzyme complex(GO:0031510)
0.1 0.4 GO:0071203 WASH complex(GO:0071203)
0.1 5.7 GO:0001725 stress fiber(GO:0001725) contractile actin filament bundle(GO:0097517)
0.1 0.6 GO:0008541 proteasome regulatory particle, lid subcomplex(GO:0008541)
0.0 0.2 GO:0001652 granular component(GO:0001652)
0.0 0.2 GO:0043020 NADPH oxidase complex(GO:0043020)
0.0 0.6 GO:0035686 sperm fibrous sheath(GO:0035686)
0.0 0.3 GO:0042406 extrinsic component of endoplasmic reticulum membrane(GO:0042406)
0.0 0.4 GO:0000015 phosphopyruvate hydratase complex(GO:0000015)
0.0 1.0 GO:0030285 integral component of synaptic vesicle membrane(GO:0030285) intrinsic component of synaptic vesicle membrane(GO:0098563)
0.0 0.4 GO:0089701 U2AF(GO:0089701)
0.0 0.2 GO:0005745 m-AAA complex(GO:0005745)
0.0 0.4 GO:0031931 TORC1 complex(GO:0031931)
0.0 0.3 GO:0045261 mitochondrial proton-transporting ATP synthase complex, catalytic core F(1)(GO:0000275) proton-transporting ATP synthase complex, catalytic core F(1)(GO:0045261)
0.0 0.8 GO:0098839 postsynaptic density membrane(GO:0098839) postsynaptic specialization membrane(GO:0099634)
0.0 0.2 GO:0000308 cytoplasmic cyclin-dependent protein kinase holoenzyme complex(GO:0000308)
0.0 1.5 GO:0097440 apical dendrite(GO:0097440)
0.0 0.4 GO:0019773 proteasome core complex, alpha-subunit complex(GO:0019773)
0.0 0.8 GO:0002080 acrosomal membrane(GO:0002080)
0.0 3.7 GO:0000118 histone deacetylase complex(GO:0000118)
0.0 0.3 GO:0005850 eukaryotic translation initiation factor 2 complex(GO:0005850)
0.0 0.1 GO:0033596 TSC1-TSC2 complex(GO:0033596)
0.0 0.1 GO:0071006 U2-type catalytic step 1 spliceosome(GO:0071006)
0.0 0.5 GO:0097228 sperm principal piece(GO:0097228)
0.0 1.1 GO:0000314 organellar small ribosomal subunit(GO:0000314) mitochondrial small ribosomal subunit(GO:0005763)
0.0 0.2 GO:0046696 lipopolysaccharide receptor complex(GO:0046696)
0.0 0.7 GO:0005782 peroxisomal matrix(GO:0005782) microbody lumen(GO:0031907)
0.0 0.1 GO:0071920 cleavage body(GO:0071920)
0.0 0.8 GO:0071565 nBAF complex(GO:0071565)
0.0 0.6 GO:0000145 exocyst(GO:0000145)
0.0 0.2 GO:0005956 protein kinase CK2 complex(GO:0005956)
0.0 0.3 GO:0009925 basal plasma membrane(GO:0009925)
0.0 0.3 GO:0031588 nucleotide-activated protein kinase complex(GO:0031588)
0.0 0.3 GO:0072546 ER membrane protein complex(GO:0072546)
0.0 1.4 GO:0044295 axonal growth cone(GO:0044295)
0.0 1.1 GO:0045271 mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
0.0 0.3 GO:0005952 cAMP-dependent protein kinase complex(GO:0005952)
0.0 0.1 GO:0005638 lamin filament(GO:0005638)
0.0 0.3 GO:0000276 mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276)
0.0 0.1 GO:0005672 transcription factor TFIIA complex(GO:0005672)
0.0 0.5 GO:0098827 endoplasmic reticulum tubular network(GO:0071782) endoplasmic reticulum subcompartment(GO:0098827)
0.0 0.1 GO:0031417 NatC complex(GO:0031417)
0.0 2.0 GO:0005911 cell-cell junction(GO:0005911)
0.0 0.6 GO:0035371 microtubule plus-end(GO:0035371)
0.0 0.9 GO:0030173 integral component of Golgi membrane(GO:0030173) intrinsic component of Golgi membrane(GO:0031228)
0.0 0.6 GO:0032391 photoreceptor connecting cilium(GO:0032391)
0.0 0.1 GO:0033061 DNA recombinase mediator complex(GO:0033061)
0.0 0.9 GO:0005881 cytoplasmic microtubule(GO:0005881)
0.0 0.2 GO:0030688 preribosome, small subunit precursor(GO:0030688)
0.0 0.4 GO:0070382 exocytic vesicle(GO:0070382)
0.0 0.1 GO:0000214 tRNA-intron endonuclease complex(GO:0000214)
0.0 0.2 GO:0030126 COPI vesicle coat(GO:0030126)
0.0 0.3 GO:0005640 nuclear outer membrane(GO:0005640)
0.0 0.3 GO:0042611 MHC protein complex(GO:0042611)
0.0 0.5 GO:0032420 stereocilium(GO:0032420)
0.0 2.3 GO:0005924 cell-substrate adherens junction(GO:0005924) focal adhesion(GO:0005925) cell-substrate junction(GO:0030055)
0.0 0.5 GO:0035145 exon-exon junction complex(GO:0035145)
0.0 0.2 GO:0042788 polysomal ribosome(GO:0042788)
0.0 0.9 GO:0030018 Z disc(GO:0030018)
0.0 0.5 GO:0032588 trans-Golgi network membrane(GO:0032588)
0.0 0.3 GO:0005770 late endosome(GO:0005770)
0.0 0.2 GO:0031083 BLOC-1 complex(GO:0031083)
0.0 0.9 GO:0072562 blood microparticle(GO:0072562)
0.0 0.2 GO:0005852 eukaryotic translation initiation factor 3 complex(GO:0005852)
0.0 0.8 GO:0016529 sarcoplasmic reticulum(GO:0016529)
0.0 0.1 GO:1990726 Lsm1-7-Pat1 complex(GO:1990726)
0.0 0.4 GO:0014704 intercalated disc(GO:0014704)
0.0 1.9 GO:0030027 lamellipodium(GO:0030027)
0.0 0.1 GO:0097413 Lewy body(GO:0097413)
0.0 0.2 GO:0036038 MKS complex(GO:0036038)
0.0 0.3 GO:0001772 immunological synapse(GO:0001772)
0.0 1.2 GO:0005923 bicellular tight junction(GO:0005923)
0.0 2.1 GO:0098852 lysosomal membrane(GO:0005765) lytic vacuole membrane(GO:0098852)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
1.2 3.6 GO:0004980 melanocortin receptor activity(GO:0004977) melanocyte-stimulating hormone receptor activity(GO:0004980)
0.8 2.3 GO:0004698 calcium-dependent protein kinase C activity(GO:0004698)
0.6 2.6 GO:0050833 pyruvate transmembrane transporter activity(GO:0050833)
0.5 2.2 GO:0047237 glucuronylgalactosylproteoglycan 4-beta-N-acetylgalactosaminyltransferase activity(GO:0047237) glucuronosyl-N-acetylgalactosaminyl-proteoglycan 4-beta-N-acetylgalactosaminyltransferase activity(GO:0047238)
0.5 1.4 GO:0004993 G-protein coupled serotonin receptor activity(GO:0004993)
0.4 1.8 GO:0030160 GKAP/Homer scaffold activity(GO:0030160)
0.4 1.3 GO:0008732 threonine aldolase activity(GO:0004793) L-allo-threonine aldolase activity(GO:0008732)
0.4 1.6 GO:0005222 intracellular cAMP activated cation channel activity(GO:0005222)
0.4 1.6 GO:0004459 L-lactate dehydrogenase activity(GO:0004459)
0.4 1.1 GO:0004574 oligo-1,6-glucosidase activity(GO:0004574)
0.4 1.1 GO:0005128 erythropoietin receptor binding(GO:0005128)
0.3 1.4 GO:0008970 phosphatidylcholine 1-acylhydrolase activity(GO:0008970)
0.3 1.6 GO:0008449 N-acetylglucosamine-6-sulfatase activity(GO:0008449)
0.3 1.9 GO:0008294 calcium- and calmodulin-responsive adenylate cyclase activity(GO:0008294)
0.3 3.6 GO:0036042 long-chain fatty acyl-CoA binding(GO:0036042)
0.3 2.2 GO:0008093 cytoskeletal adaptor activity(GO:0008093)
0.3 0.8 GO:0031896 V2 vasopressin receptor binding(GO:0031896)
0.3 2.0 GO:0048495 Roundabout binding(GO:0048495)
0.2 0.7 GO:0072541 peroxynitrite reductase activity(GO:0072541)
0.2 1.4 GO:0023029 MHC class Ib protein binding(GO:0023029)
0.2 1.2 GO:0030618 transforming growth factor beta receptor, pathway-specific cytoplasmic mediator activity(GO:0030618)
0.2 0.7 GO:0070052 collagen V binding(GO:0070052)
0.2 0.7 GO:0008502 melatonin receptor activity(GO:0008502)
0.2 1.8 GO:0005025 transforming growth factor beta receptor activity, type I(GO:0005025)
0.2 1.0 GO:0097643 amylin receptor activity(GO:0097643)
0.2 0.6 GO:0015232 heme transporter activity(GO:0015232)
0.2 1.3 GO:0001665 alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity(GO:0001665)
0.2 2.2 GO:0004089 carbonate dehydratase activity(GO:0004089)
0.2 0.5 GO:0036470 tyrosine 3-monooxygenase activator activity(GO:0036470) L-dopa decarboxylase activator activity(GO:0036478)
0.2 2.3 GO:0008301 DNA binding, bending(GO:0008301)
0.2 0.7 GO:0008332 low voltage-gated calcium channel activity(GO:0008332)
0.2 1.2 GO:0015379 potassium:chloride symporter activity(GO:0015379) potassium ion symporter activity(GO:0022820)
0.2 1.3 GO:0015181 arginine transmembrane transporter activity(GO:0015181)
0.2 1.5 GO:0003857 3-hydroxyacyl-CoA dehydrogenase activity(GO:0003857)
0.1 0.4 GO:0017057 6-phosphogluconolactonase activity(GO:0017057)
0.1 1.4 GO:0004806 triglyceride lipase activity(GO:0004806)
0.1 0.4 GO:0008330 protein tyrosine/threonine phosphatase activity(GO:0008330)
0.1 0.9 GO:0004614 phosphoglucomutase activity(GO:0004614)
0.1 0.8 GO:0045028 G-protein coupled nucleotide receptor activity(GO:0001608) G-protein coupled purinergic nucleotide receptor activity(GO:0045028)
0.1 1.2 GO:0019865 immunoglobulin binding(GO:0019865)
0.1 1.3 GO:0015347 sodium-independent organic anion transmembrane transporter activity(GO:0015347)
0.1 0.4 GO:0005459 UDP-galactose transmembrane transporter activity(GO:0005459)
0.1 3.6 GO:0035259 glucocorticoid receptor binding(GO:0035259)
0.1 0.4 GO:0019962 interferon receptor activity(GO:0004904) type I interferon receptor activity(GO:0004905) type I interferon binding(GO:0019962)
0.1 0.6 GO:0016453 acetyl-CoA C-acetyltransferase activity(GO:0003985) C-acetyltransferase activity(GO:0016453)
0.1 0.3 GO:0004069 L-aspartate:2-oxoglutarate aminotransferase activity(GO:0004069)
0.1 1.0 GO:0010857 calcium-dependent protein kinase activity(GO:0010857)
0.1 0.5 GO:0004809 tRNA (guanine-N2-)-methyltransferase activity(GO:0004809)
0.1 0.4 GO:0050347 trans-hexaprenyltranstransferase activity(GO:0000010) trans-octaprenyltranstransferase activity(GO:0050347)
0.1 1.2 GO:0016863 intramolecular oxidoreductase activity, transposing C=C bonds(GO:0016863)
0.1 2.1 GO:0005520 insulin-like growth factor binding(GO:0005520)
0.1 0.9 GO:0050291 sphingosine N-acyltransferase activity(GO:0050291)
0.1 0.3 GO:0004155 6,7-dihydropteridine reductase activity(GO:0004155)
0.1 0.3 GO:0009918 sterol delta7 reductase activity(GO:0009918) 7-dehydrocholesterol reductase activity(GO:0047598)
0.1 2.4 GO:0019707 protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)
0.1 0.2 GO:0046624 sphingolipid transporter activity(GO:0046624)
0.1 0.7 GO:0000774 adenyl-nucleotide exchange factor activity(GO:0000774)
0.1 0.2 GO:0031779 melanocortin receptor binding(GO:0031779) type 3 melanocortin receptor binding(GO:0031781) type 4 melanocortin receptor binding(GO:0031782)
0.1 0.3 GO:0003836 beta-galactoside (CMP) alpha-2,3-sialyltransferase activity(GO:0003836)
0.1 0.2 GO:0005006 epidermal growth factor-activated receptor activity(GO:0005006)
0.1 0.2 GO:0042134 snoRNP binding(GO:0030519) rRNA primary transcript binding(GO:0042134)
0.1 0.3 GO:0004582 dolichyl-phosphate beta-D-mannosyltransferase activity(GO:0004582)
0.1 1.3 GO:0005528 macrolide binding(GO:0005527) FK506 binding(GO:0005528)
0.1 0.8 GO:0032036 myosin heavy chain binding(GO:0032036)
0.1 0.3 GO:0004656 procollagen-proline 4-dioxygenase activity(GO:0004656) procollagen-proline dioxygenase activity(GO:0019798)
0.1 1.0 GO:0017070 U6 snRNA binding(GO:0017070)
0.1 3.0 GO:0015485 cholesterol binding(GO:0015485)
0.1 0.4 GO:0008242 omega peptidase activity(GO:0008242)
0.1 0.9 GO:0031005 filamin binding(GO:0031005)
0.1 0.3 GO:0008545 JUN kinase kinase activity(GO:0008545)
0.1 0.8 GO:0008097 5S rRNA binding(GO:0008097)
0.1 0.4 GO:0004118 cGMP-stimulated cyclic-nucleotide phosphodiesterase activity(GO:0004118)
0.1 0.2 GO:0003692 left-handed Z-DNA binding(GO:0003692)
0.1 0.4 GO:0015091 ferric iron transmembrane transporter activity(GO:0015091) trivalent inorganic cation transmembrane transporter activity(GO:0072510)
0.1 0.2 GO:0031545 peptidyl-proline 4-dioxygenase activity(GO:0031545)
0.1 1.3 GO:0031078 histone deacetylase activity (H3-K14 specific)(GO:0031078) NAD-dependent histone deacetylase activity (H3-K14 specific)(GO:0032041)
0.1 2.1 GO:0050699 WW domain binding(GO:0050699)
0.1 0.6 GO:0071933 Arp2/3 complex binding(GO:0071933)
0.1 0.5 GO:0035612 AP-2 adaptor complex binding(GO:0035612)
0.1 1.6 GO:0030552 cAMP binding(GO:0030552)
0.1 0.2 GO:0019002 GMP binding(GO:0019002)
0.1 0.5 GO:0015266 protein channel activity(GO:0015266)
0.1 2.8 GO:0035255 ionotropic glutamate receptor binding(GO:0035255)
0.1 0.4 GO:0009019 tRNA (guanine-N1-)-methyltransferase activity(GO:0009019)
0.1 3.2 GO:0005546 phosphatidylinositol-4,5-bisphosphate binding(GO:0005546)
0.1 0.2 GO:0008073 ornithine decarboxylase inhibitor activity(GO:0008073)
0.1 0.6 GO:0004017 adenylate kinase activity(GO:0004017)
0.0 0.6 GO:0005537 mannose binding(GO:0005537)
0.0 0.7 GO:0043325 phosphatidylinositol-3,4-bisphosphate binding(GO:0043325)
0.0 0.3 GO:0005094 Rho GDP-dissociation inhibitor activity(GO:0005094)
0.0 0.3 GO:0003828 alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity(GO:0003828)
0.0 0.4 GO:0008484 sulfuric ester hydrolase activity(GO:0008484)
0.0 2.6 GO:0046875 ephrin receptor binding(GO:0046875)
0.0 0.2 GO:0016175 superoxide-generating NADPH oxidase activity(GO:0016175)
0.0 0.2 GO:0005290 L-histidine transmembrane transporter activity(GO:0005290)
0.0 0.3 GO:0042296 ISG15 transferase activity(GO:0042296)
0.0 1.2 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.0 0.3 GO:0004679 AMP-activated protein kinase activity(GO:0004679)
0.0 0.4 GO:0004634 phosphopyruvate hydratase activity(GO:0004634)
0.0 2.1 GO:0016876 aminoacyl-tRNA ligase activity(GO:0004812) ligase activity, forming carbon-oxygen bonds(GO:0016875) ligase activity, forming aminoacyl-tRNA and related compounds(GO:0016876)
0.0 0.2 GO:0005093 Rab GDP-dissociation inhibitor activity(GO:0005093)
0.0 0.5 GO:0070742 C2H2 zinc finger domain binding(GO:0070742)
0.0 0.7 GO:0005159 insulin-like growth factor receptor binding(GO:0005159)
0.0 0.2 GO:0072345 NAADP-sensitive calcium-release channel activity(GO:0072345)
0.0 0.5 GO:0015643 toxic substance binding(GO:0015643)
0.0 0.2 GO:0001010 transcription factor activity, sequence-specific DNA binding transcription factor recruiting(GO:0001010)
0.0 1.7 GO:0008138 protein tyrosine/serine/threonine phosphatase activity(GO:0008138)
0.0 0.3 GO:0004630 phospholipase D activity(GO:0004630)
0.0 0.1 GO:0016812 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides(GO:0016812)
0.0 1.1 GO:0017134 fibroblast growth factor binding(GO:0017134)
0.0 0.6 GO:0046933 proton-transporting ATP synthase activity, rotational mechanism(GO:0046933)
0.0 0.6 GO:0005388 calcium-transporting ATPase activity(GO:0005388)
0.0 0.3 GO:0004862 cAMP-dependent protein kinase inhibitor activity(GO:0004862)
0.0 1.6 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.0 0.1 GO:0030984 kininogen binding(GO:0030984)
0.0 0.6 GO:0003950 NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.0 0.3 GO:0001135 transcription factor activity, RNA polymerase II transcription factor recruiting(GO:0001135)
0.0 1.6 GO:0030507 spectrin binding(GO:0030507)
0.0 1.8 GO:0051287 NAD binding(GO:0051287)
0.0 2.3 GO:0004004 RNA helicase activity(GO:0003724) ATP-dependent RNA helicase activity(GO:0004004)
0.0 0.4 GO:0016500 protein-hormone receptor activity(GO:0016500)
0.0 0.5 GO:0050811 GABA receptor binding(GO:0050811)
0.0 0.1 GO:0031735 CCR10 chemokine receptor binding(GO:0031735)
0.0 0.3 GO:0043024 ribosomal small subunit binding(GO:0043024)
0.0 0.3 GO:0004691 cAMP-dependent protein kinase activity(GO:0004691)
0.0 0.8 GO:0050750 low-density lipoprotein particle receptor binding(GO:0050750)
0.0 1.3 GO:0004693 cyclin-dependent protein serine/threonine kinase activity(GO:0004693)
0.0 0.2 GO:0000213 tRNA-intron endonuclease activity(GO:0000213) endoribonuclease activity, producing 3'-phosphomonoesters(GO:0016892)
0.0 1.0 GO:0019239 deaminase activity(GO:0019239)
0.0 0.6 GO:0071617 lysophospholipid acyltransferase activity(GO:0071617)
0.0 0.3 GO:0008556 sodium:potassium-exchanging ATPase activity(GO:0005391) potassium-transporting ATPase activity(GO:0008556)
0.0 0.4 GO:0017166 vinculin binding(GO:0017166)
0.0 0.4 GO:0042056 chemoattractant activity(GO:0042056)
0.0 1.0 GO:0031624 ubiquitin conjugating enzyme binding(GO:0031624)
0.0 0.8 GO:0019200 carbohydrate kinase activity(GO:0019200)
0.0 0.5 GO:0001968 fibronectin binding(GO:0001968)
0.0 0.9 GO:0005496 steroid binding(GO:0005496)
0.0 0.4 GO:0003746 translation elongation factor activity(GO:0003746)
0.0 0.2 GO:0031419 cobalamin binding(GO:0031419)
0.0 0.3 GO:0005536 glucose binding(GO:0005536)
0.0 0.2 GO:0061676 importin-alpha family protein binding(GO:0061676)
0.0 0.3 GO:0015020 glucuronosyltransferase activity(GO:0015020)
0.0 0.5 GO:0042605 peptide antigen binding(GO:0042605)
0.0 1.3 GO:0005200 structural constituent of cytoskeleton(GO:0005200)
0.0 0.6 GO:0008198 ferrous iron binding(GO:0008198)
0.0 0.6 GO:0043015 gamma-tubulin binding(GO:0043015)
0.0 0.4 GO:0008171 O-methyltransferase activity(GO:0008171)
0.0 0.1 GO:0033691 sialic acid binding(GO:0033691)
0.0 0.2 GO:0035312 5'-3' exodeoxyribonuclease activity(GO:0035312)
0.0 0.6 GO:0043027 cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027)
0.0 0.1 GO:0043023 ribosomal large subunit binding(GO:0043023)
0.0 0.4 GO:0016709 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen(GO:0016709)
0.0 0.1 GO:0008131 primary amine oxidase activity(GO:0008131)
0.0 0.3 GO:0008510 sodium:bicarbonate symporter activity(GO:0008510)
0.0 0.4 GO:0048020 CCR chemokine receptor binding(GO:0048020)
0.0 0.4 GO:0017112 Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.0 0.7 GO:0005507 copper ion binding(GO:0005507)
0.0 0.1 GO:0004111 creatine kinase activity(GO:0004111)
0.0 0.0 GO:0046997 sarcosine dehydrogenase activity(GO:0008480) oxidoreductase activity, acting on the CH-NH group of donors, flavin as acceptor(GO:0046997)
0.0 0.4 GO:0005154 epidermal growth factor receptor binding(GO:0005154)
0.0 1.3 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.0 0.1 GO:0008889 glycerophosphodiester phosphodiesterase activity(GO:0008889)
0.0 0.3 GO:0043014 alpha-tubulin binding(GO:0043014)
0.0 0.4 GO:0017080 sodium channel regulator activity(GO:0017080)
0.0 0.2 GO:0017049 GTP-Rho binding(GO:0017049)
0.0 0.2 GO:0070006 metalloaminopeptidase activity(GO:0070006)
0.0 0.1 GO:0004311 farnesyltranstransferase activity(GO:0004311)
0.0 0.1 GO:0008430 selenium binding(GO:0008430)
0.0 0.2 GO:0001530 lipopolysaccharide binding(GO:0001530)
0.0 0.9 GO:0051087 chaperone binding(GO:0051087)
0.0 0.4 GO:0005261 cation channel activity(GO:0005261)
0.0 0.1 GO:0042043 neurexin family protein binding(GO:0042043)
0.0 0.1 GO:1990190 peptide-glutamate-N-acetyltransferase activity(GO:1990190)
0.0 0.3 GO:0070273 phosphatidylinositol-4-phosphate binding(GO:0070273)
0.0 0.1 GO:0001846 opsonin binding(GO:0001846)
0.0 1.0 GO:0030674 protein binding, bridging(GO:0030674)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 3.8 PID_SYNDECAN_3_PATHWAY Syndecan-3-mediated signaling events
0.1 1.9 PID_LPA4_PATHWAY LPA4-mediated signaling events
0.1 3.8 PID_IL8_CXCR1_PATHWAY IL8- and CXCR1-mediated signaling events
0.1 2.9 PID_HDAC_CLASSIII_PATHWAY Signaling events mediated by HDAC Class III
0.1 1.4 PID_LYMPH_ANGIOGENESIS_PATHWAY VEGFR3 signaling in lymphatic endothelium
0.1 2.6 PID_EPHA_FWDPATHWAY EPHA forward signaling
0.1 2.9 PID_RETINOIC_ACID_PATHWAY Retinoic acid receptors-mediated signaling
0.1 2.2 PID_ER_NONGENOMIC_PATHWAY Plasma membrane estrogen receptor signaling
0.0 1.2 PID_SMAD2_3PATHWAY Regulation of cytoplasmic and nuclear SMAD2/3 signaling
0.0 1.1 PID_PI3K_PLC_TRK_PATHWAY Trk receptor signaling mediated by PI3K and PLC-gamma
0.0 0.9 PID_ALPHA_SYNUCLEIN_PATHWAY Alpha-synuclein signaling
0.0 0.5 SA_G1_AND_S_PHASES Cdk2, 4, and 6 bind cyclin D in G1, while cdk2/cyclin E promotes the G1/S transition.
0.0 0.7 PID_CIRCADIAN_PATHWAY Circadian rhythm pathway
0.0 0.4 PID_ANTHRAX_PATHWAY Cellular roles of Anthrax toxin
0.0 1.5 PID_CD8_TCR_DOWNSTREAM_PATHWAY Downstream signaling in naïve CD8+ T cells
0.0 0.5 PID_MAPK_TRK_PATHWAY Trk receptor signaling mediated by the MAPK pathway
0.0 1.6 PID_HEDGEHOG_GLI_PATHWAY Hedgehog signaling events mediated by Gli proteins
0.0 1.0 PID_INTEGRIN_A4B1_PATHWAY Alpha4 beta1 integrin signaling events
0.0 0.2 PID_RANBP2_PATHWAY Sumoylation by RanBP2 regulates transcriptional repression
0.0 1.3 PID_RAC1_PATHWAY RAC1 signaling pathway
0.0 1.3 PID_HES_HEY_PATHWAY Notch-mediated HES/HEY network
0.0 1.2 PID_ILK_PATHWAY Integrin-linked kinase signaling
0.0 0.6 PID_EPO_PATHWAY EPO signaling pathway
0.0 0.7 PID_HDAC_CLASSII_PATHWAY Signaling events mediated by HDAC Class II
0.0 0.5 PID_ARF_3PATHWAY Arf1 pathway
0.0 0.7 PID_PI3KCI_PATHWAY Class I PI3K signaling events
0.0 3.2 NABA_ECM_REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.0 0.4 PID_UPA_UPAR_PATHWAY Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling
0.0 3.0 NABA_ECM_GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.0 1.1 PID_HIF1_TFPATHWAY HIF-1-alpha transcription factor network
0.0 0.4 PID_P38_ALPHA_BETA_PATHWAY Regulation of p38-alpha and p38-beta
0.0 0.3 PID_EPHRINB_REV_PATHWAY Ephrin B reverse signaling
0.0 0.2 PID_NFKAPPAB_ATYPICAL_PATHWAY Atypical NF-kappaB pathway
0.0 0.6 PID_REG_GR_PATHWAY Glucocorticoid receptor regulatory network
0.0 0.1 SA_B_CELL_RECEPTOR_COMPLEXES Antigen binding to B cell receptors activates protein tyrosine kinases, such as the Src family, which ultimate activate MAP kinases.
0.0 0.8 PID_PDGFRB_PATHWAY PDGFR-beta signaling pathway
0.0 0.6 PID_P53_REGULATION_PATHWAY p53 pathway
0.0 0.3 ST_INTEGRIN_SIGNALING_PATHWAY Integrin Signaling Pathway
0.0 0.2 SA_CASPASE_CASCADE Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade.
0.0 0.4 PID_BMP_PATHWAY BMP receptor signaling
0.0 0.3 PID_VEGFR1_2_PATHWAY Signaling events mediated by VEGFR1 and VEGFR2

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 1.4 REACTOME_SEROTONIN_RECEPTORS Genes involved in Serotonin receptors
0.3 2.6 REACTOME_BILE_SALT_AND_ORGANIC_ANION_SLC_TRANSPORTERS Genes involved in Bile salt and organic anion SLC transporters
0.2 3.1 REACTOME_PLATELET_ADHESION_TO_EXPOSED_COLLAGEN Genes involved in Platelet Adhesion to exposed collagen
0.2 1.3 REACTOME_TRANSPORT_OF_ORGANIC_ANIONS Genes involved in Transport of organic anions
0.2 1.9 REACTOME_ADENYLATE_CYCLASE_ACTIVATING_PATHWAY Genes involved in Adenylate cyclase activating pathway
0.2 3.9 REACTOME_DCC_MEDIATED_ATTRACTIVE_SIGNALING Genes involved in DCC mediated attractive signaling
0.1 1.1 REACTOME_REGULATION_OF_INSULIN_SECRETION_BY_ACETYLCHOLINE Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.1 2.3 REACTOME_PYRUVATE_METABOLISM Genes involved in Pyruvate metabolism
0.1 2.9 REACTOME_CELL_EXTRACELLULAR_MATRIX_INTERACTIONS Genes involved in Cell-extracellular matrix interactions
0.1 2.2 REACTOME_CHONDROITIN_SULFATE_BIOSYNTHESIS Genes involved in Chondroitin sulfate biosynthesis
0.1 2.2 REACTOME_SIGNALING_BY_NODAL Genes involved in Signaling by NODAL
0.1 1.0 REACTOME_REGULATION_OF_WATER_BALANCE_BY_RENAL_AQUAPORINS Genes involved in Regulation of Water Balance by Renal Aquaporins
0.1 1.3 REACTOME_NEF_MEDIATED_DOWNREGULATION_OF_MHC_CLASS_I_COMPLEX_CELL_SURFACE_EXPRESSION Genes involved in Nef mediated downregulation of MHC class I complex cell surface expression
0.1 0.8 REACTOME_P2Y_RECEPTORS Genes involved in P2Y receptors
0.1 2.5 REACTOME_CYTOSOLIC_TRNA_AMINOACYLATION Genes involved in Cytosolic tRNA aminoacylation
0.1 3.0 REACTOME_INTERACTION_BETWEEN_L1_AND_ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.1 0.6 REACTOME_ACYL_CHAIN_REMODELLING_OF_PI Genes involved in Acyl chain remodelling of PI
0.1 2.1 REACTOME_DEADENYLATION_OF_MRNA Genes involved in Deadenylation of mRNA
0.1 2.3 REACTOME_CA_DEPENDENT_EVENTS Genes involved in Ca-dependent events
0.1 1.2 REACTOME_ZINC_TRANSPORTERS Genes involved in Zinc transporters
0.1 0.9 REACTOME_BMAL1_CLOCK_NPAS2_ACTIVATES_CIRCADIAN_EXPRESSION Genes involved in BMAL1:CLOCK/NPAS2 Activates Circadian Expression
0.1 0.9 REACTOME_POST_CHAPERONIN_TUBULIN_FOLDING_PATHWAY Genes involved in Post-chaperonin tubulin folding pathway
0.0 0.5 REACTOME_DEGRADATION_OF_THE_EXTRACELLULAR_MATRIX Genes involved in Degradation of the extracellular matrix
0.0 0.7 REACTOME_REGULATION_OF_INSULIN_LIKE_GROWTH_FACTOR_IGF_ACTIVITY_BY_INSULIN_LIKE_GROWTH_FACTOR_BINDING_PROTEINS_IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.0 0.8 REACTOME_MITOCHONDRIAL_TRNA_AMINOACYLATION Genes involved in Mitochondrial tRNA aminoacylation
0.0 0.8 REACTOME_PTM_GAMMA_CARBOXYLATION_HYPUSINE_FORMATION_AND_ARYLSULFATASE_ACTIVATION Genes involved in PTM: gamma carboxylation, hypusine formation and arylsulfatase activation
0.0 2.1 REACTOME_AMINO_ACID_AND_OLIGOPEPTIDE_SLC_TRANSPORTERS Genes involved in Amino acid and oligopeptide SLC transporters
0.0 0.4 REACTOME_REGULATION_OF_IFNA_SIGNALING Genes involved in Regulation of IFNA signaling
0.0 2.0 REACTOME_GOLGI_ASSOCIATED_VESICLE_BIOGENESIS Genes involved in Golgi Associated Vesicle Biogenesis
0.0 0.4 REACTOME_IL_7_SIGNALING Genes involved in Interleukin-7 signaling
0.0 3.4 REACTOME_G_ALPHA_S_SIGNALLING_EVENTS Genes involved in G alpha (s) signalling events
0.0 0.6 REACTOME_FORMATION_OF_ATP_BY_CHEMIOSMOTIC_COUPLING Genes involved in Formation of ATP by chemiosmotic coupling
0.0 1.6 REACTOME_MITOCHONDRIAL_PROTEIN_IMPORT Genes involved in Mitochondrial Protein Import
0.0 0.5 REACTOME_METABOLISM_OF_POLYAMINES Genes involved in Metabolism of polyamines
0.0 0.5 REACTOME_SYNTHESIS_OF_PIPS_AT_THE_GOLGI_MEMBRANE Genes involved in Synthesis of PIPs at the Golgi membrane
0.0 0.5 REACTOME_TRAF3_DEPENDENT_IRF_ACTIVATION_PATHWAY Genes involved in TRAF3-dependent IRF activation pathway
0.0 2.4 REACTOME_NRAGE_SIGNALS_DEATH_THROUGH_JNK Genes involved in NRAGE signals death through JNK
0.0 0.2 REACTOME_REGULATION_OF_IFNG_SIGNALING Genes involved in Regulation of IFNG signaling
0.0 0.4 REACTOME_REGULATION_OF_RHEB_GTPASE_ACTIVITY_BY_AMPK Genes involved in Regulation of Rheb GTPase activity by AMPK
0.0 0.1 REACTOME_INTRINSIC_PATHWAY Genes involved in Intrinsic Pathway
0.0 1.2 REACTOME_TRANSPORT_OF_INORGANIC_CATIONS_ANIONS_AND_AMINO_ACIDS_OLIGOPEPTIDES Genes involved in Transport of inorganic cations/anions and amino acids/oligopeptides
0.0 0.3 REACTOME_CHYLOMICRON_MEDIATED_LIPID_TRANSPORT Genes involved in Chylomicron-mediated lipid transport
0.0 0.2 REACTOME_COPI_MEDIATED_TRANSPORT Genes involved in COPI Mediated Transport
0.0 0.5 REACTOME_AKT_PHOSPHORYLATES_TARGETS_IN_THE_CYTOSOL Genes involved in AKT phosphorylates targets in the cytosol
0.0 1.6 REACTOME_POTASSIUM_CHANNELS Genes involved in Potassium Channels
0.0 0.6 REACTOME_ERK_MAPK_TARGETS Genes involved in ERK/MAPK targets
0.0 0.3 REACTOME_PRE_NOTCH_PROCESSING_IN_GOLGI Genes involved in Pre-NOTCH Processing in Golgi
0.0 0.5 REACTOME_SYNTHESIS_AND_INTERCONVERSION_OF_NUCLEOTIDE_DI_AND_TRIPHOSPHATES Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.0 0.7 REACTOME_ION_TRANSPORT_BY_P_TYPE_ATPASES Genes involved in Ion transport by P-type ATPases
0.0 0.2 REACTOME_AMINE_DERIVED_HORMONES Genes involved in Amine-derived hormones
0.0 1.0 REACTOME_REGULATION_OF_ORNITHINE_DECARBOXYLASE_ODC Genes involved in Regulation of ornithine decarboxylase (ODC)
0.0 0.3 REACTOME_SYNTHESIS_OF_SUBSTRATES_IN_N_GLYCAN_BIOSYTHESIS Genes involved in Synthesis of substrates in N-glycan biosythesis
0.0 0.1 REACTOME_CREATION_OF_C4_AND_C2_ACTIVATORS Genes involved in Creation of C4 and C2 activators
0.0 0.4 REACTOME_SIGNALING_BY_BMP Genes involved in Signaling by BMP
0.0 0.3 REACTOME_GRB2_EVENTS_IN_ERBB2_SIGNALING Genes involved in GRB2 events in ERBB2 signaling
0.0 0.4 REACTOME_CLASS_B_2_SECRETIN_FAMILY_RECEPTORS Genes involved in Class B/2 (Secretin family receptors)
0.0 0.7 REACTOME_MRNA_SPLICING_MINOR_PATHWAY Genes involved in mRNA Splicing - Minor Pathway
0.0 0.3 REACTOME_INTERFERON_ALPHA_BETA_SIGNALING Genes involved in Interferon alpha/beta signaling
0.0 0.2 REACTOME_OXYGEN_DEPENDENT_PROLINE_HYDROXYLATION_OF_HYPOXIA_INDUCIBLE_FACTOR_ALPHA Genes involved in Oxygen-dependent Proline Hydroxylation of Hypoxia-inducible Factor Alpha
0.0 0.3 REACTOME_CHOLESTEROL_BIOSYNTHESIS Genes involved in Cholesterol biosynthesis
0.0 1.4 REACTOME_PPARA_ACTIVATES_GENE_EXPRESSION Genes involved in PPARA Activates Gene Expression
0.0 0.2 REACTOME_SYNTHESIS_SECRETION_AND_DEACYLATION_OF_GHRELIN Genes involved in Synthesis, Secretion, and Deacylation of Ghrelin
0.0 0.2 REACTOME_MRNA_DECAY_BY_5_TO_3_EXORIBONUCLEASE Genes involved in mRNA Decay by 5' to 3' Exoribonuclease
0.0 0.3 REACTOME_SYNTHESIS_OF_PA Genes involved in Synthesis of PA
0.0 0.7 REACTOME_NOTCH1_INTRACELLULAR_DOMAIN_REGULATES_TRANSCRIPTION Genes involved in NOTCH1 Intracellular Domain Regulates Transcription
0.0 0.1 REACTOME_FORMATION_OF_TUBULIN_FOLDING_INTERMEDIATES_BY_CCT_TRIC Genes involved in Formation of tubulin folding intermediates by CCT/TriC
0.0 0.0 REACTOME_DOWNSTREAM_TCR_SIGNALING Genes involved in Downstream TCR signaling
0.0 0.2 REACTOME_PYRIMIDINE_METABOLISM Genes involved in Pyrimidine metabolism