Motif ID: Esrrb_Esrra
Z-value: 1.364


Transcription factors associated with Esrrb_Esrra:
Gene Symbol | Entrez ID | Gene Name |
---|---|---|
Esrra | ENSMUSG00000024955.7 | Esrra |
Esrrb | ENSMUSG00000021255.11 | Esrrb |
Activity-expression correlation:
Gene Symbol | Promoter | Pearson corr. coef. | P-value | Plot |
---|---|---|---|---|
Esrrb | mm10_v2_chr12_+_86361112_86361131 | -0.23 | 1.8e-01 | Click! |
Esrra | mm10_v2_chr19_-_6921753_6921803 | -0.05 | 7.7e-01 | Click! |
Top targets:
Showing 1 to 20 of 200 entries
Gene overrepresentation in biological_process category:
Showing 1 to 20 of 248 entries
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.2 | 12.2 | GO:0071277 | cellular response to calcium ion(GO:0071277) |
0.5 | 12.1 | GO:2000060 | positive regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process(GO:2000060) |
0.9 | 11.7 | GO:0043252 | sodium-independent organic anion transport(GO:0043252) |
0.7 | 10.4 | GO:0007190 | activation of adenylate cyclase activity(GO:0007190) |
0.2 | 9.8 | GO:0045599 | negative regulation of fat cell differentiation(GO:0045599) |
1.0 | 8.8 | GO:0071420 | cellular response to histamine(GO:0071420) |
0.1 | 8.1 | GO:0035249 | synaptic transmission, glutamatergic(GO:0035249) |
0.1 | 7.7 | GO:0032091 | negative regulation of protein binding(GO:0032091) |
0.1 | 7.5 | GO:0030032 | lamellipodium assembly(GO:0030032) |
2.5 | 7.4 | GO:0021933 | radial glia guided migration of cerebellar granule cell(GO:0021933) |
0.3 | 7.0 | GO:0015985 | energy coupled proton transport, down electrochemical gradient(GO:0015985) ATP synthesis coupled proton transport(GO:0015986) |
0.7 | 6.5 | GO:0038203 | TORC2 signaling(GO:0038203) |
0.4 | 6.3 | GO:0007220 | Notch receptor processing(GO:0007220) |
0.3 | 6.3 | GO:0007214 | gamma-aminobutyric acid signaling pathway(GO:0007214) |
0.7 | 6.1 | GO:0014832 | urinary bladder smooth muscle contraction(GO:0014832) |
0.5 | 5.9 | GO:0006122 | mitochondrial electron transport, ubiquinol to cytochrome c(GO:0006122) |
0.6 | 5.1 | GO:0019388 | galactose catabolic process(GO:0019388) |
0.2 | 5.1 | GO:0014003 | oligodendrocyte development(GO:0014003) |
1.6 | 4.8 | GO:1903244 | positive regulation of cardiac muscle adaptation(GO:0010615) positive regulation of cardiac muscle hypertrophy in response to stress(GO:1903244) |
0.3 | 4.8 | GO:0050910 | detection of mechanical stimulus involved in sensory perception of sound(GO:0050910) |
Gene overrepresentation in cellular_component category:
Showing 1 to 20 of 128 entries
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.0 | 27.9 | GO:0030054 | cell junction(GO:0030054) |
1.0 | 15.0 | GO:1902711 | GABA-A receptor complex(GO:1902711) |
0.1 | 12.8 | GO:0043204 | perikaryon(GO:0043204) |
0.2 | 11.0 | GO:0009925 | basal plasma membrane(GO:0009925) |
0.1 | 10.1 | GO:0005578 | proteinaceous extracellular matrix(GO:0005578) |
0.5 | 9.7 | GO:0008074 | guanylate cyclase complex, soluble(GO:0008074) |
0.6 | 9.6 | GO:0005753 | mitochondrial proton-transporting ATP synthase complex(GO:0005753) |
0.2 | 8.2 | GO:0045271 | mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271) |
0.1 | 7.0 | GO:0000118 | histone deacetylase complex(GO:0000118) |
0.7 | 6.7 | GO:0005750 | mitochondrial respiratory chain complex III(GO:0005750) |
0.4 | 6.5 | GO:0031932 | TORC2 complex(GO:0031932) |
0.6 | 6.4 | GO:0032426 | stereocilium tip(GO:0032426) |
0.8 | 6.3 | GO:0045261 | mitochondrial proton-transporting ATP synthase complex, catalytic core F(1)(GO:0000275) proton-transporting ATP synthase complex, catalytic core F(1)(GO:0045261) |
0.4 | 6.2 | GO:0031229 | integral component of nuclear inner membrane(GO:0005639) intrinsic component of nuclear inner membrane(GO:0031229) |
0.1 | 6.1 | GO:0016363 | nuclear matrix(GO:0016363) |
0.1 | 5.4 | GO:0000315 | organellar large ribosomal subunit(GO:0000315) mitochondrial large ribosomal subunit(GO:0005762) |
0.1 | 5.4 | GO:0005604 | basement membrane(GO:0005604) |
0.2 | 5.2 | GO:0032590 | dendrite membrane(GO:0032590) |
0.6 | 5.1 | GO:0005742 | mitochondrial outer membrane translocase complex(GO:0005742) |
0.4 | 5.1 | GO:0005751 | mitochondrial respiratory chain complex IV(GO:0005751) |
Gene overrepresentation in molecular_function category:
Showing 1 to 20 of 185 entries
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.1 | 16.0 | GO:0005085 | guanyl-nucleotide exchange factor activity(GO:0005085) |
3.5 | 14.1 | GO:0004111 | creatine kinase activity(GO:0004111) |
1.7 | 11.6 | GO:0015198 | oligopeptide transporter activity(GO:0015198) |
1.7 | 10.4 | GO:0008294 | calcium- and calmodulin-responsive adenylate cyclase activity(GO:0008294) |
0.6 | 9.9 | GO:0004890 | GABA-A receptor activity(GO:0004890) |
0.4 | 8.6 | GO:0004129 | cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676) |
0.4 | 8.1 | GO:0005251 | delayed rectifier potassium channel activity(GO:0005251) |
0.0 | 8.1 | GO:0030246 | carbohydrate binding(GO:0030246) |
0.5 | 7.2 | GO:0046933 | proton-transporting ATP synthase activity, rotational mechanism(GO:0046933) |
0.2 | 7.2 | GO:0008157 | protein phosphatase 1 binding(GO:0008157) |
0.3 | 6.7 | GO:0031078 | histone deacetylase activity (H3-K14 specific)(GO:0031078) NAD-dependent histone deacetylase activity (H3-K14 specific)(GO:0032041) |
1.6 | 6.5 | GO:0005237 | inhibitory extracellular ligand-gated ion channel activity(GO:0005237) |
1.5 | 6.2 | GO:0001847 | opsonin receptor activity(GO:0001847) |
1.0 | 6.1 | GO:0035381 | extracellular ATP-gated cation channel activity(GO:0004931) ATP-gated ion channel activity(GO:0035381) mercury ion binding(GO:0045340) |
0.0 | 6.1 | GO:0003735 | structural constituent of ribosome(GO:0003735) |
0.7 | 5.5 | GO:0008121 | ubiquinol-cytochrome-c reductase activity(GO:0008121) oxidoreductase activity, acting on diphenols and related substances as donors(GO:0016679) oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor(GO:0016681) |
0.3 | 5.3 | GO:0015035 | protein disulfide oxidoreductase activity(GO:0015035) |
0.7 | 5.1 | GO:0004614 | phosphoglucomutase activity(GO:0004614) |
1.0 | 4.9 | GO:0043532 | angiostatin binding(GO:0043532) |
0.4 | 4.8 | GO:0070679 | inositol 1,4,5 trisphosphate binding(GO:0070679) |
Gene overrepresentation in C2:CP category:
Showing 1 to 20 of 31 entries
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.3 | 13.7 | PID_RAS_PATHWAY | Regulation of Ras family activation |
0.6 | 10.4 | PID_LPA4_PATHWAY | LPA4-mediated signaling events |
0.1 | 9.7 | NABA_ECM_AFFILIATED | Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins |
0.1 | 7.4 | PID_ATF2_PATHWAY | ATF-2 transcription factor network |
0.1 | 7.2 | PID_NOTCH_PATHWAY | Notch signaling pathway |
0.1 | 4.8 | PID_HDAC_CLASSII_PATHWAY | Signaling events mediated by HDAC Class II |
0.1 | 4.4 | PID_RXR_VDR_PATHWAY | RXR and RAR heterodimerization with other nuclear receptor |
0.1 | 4.3 | PID_PI3K_PLC_TRK_PATHWAY | Trk receptor signaling mediated by PI3K and PLC-gamma |
0.1 | 3.4 | PID_HIF1_TFPATHWAY | HIF-1-alpha transcription factor network |
0.0 | 3.4 | PID_MTOR_4PATHWAY | mTOR signaling pathway |
0.1 | 2.9 | PID_RET_PATHWAY | Signaling events regulated by Ret tyrosine kinase |
0.1 | 2.4 | PID_ARF_3PATHWAY | Arf1 pathway |
0.2 | 2.1 | PID_ALK2_PATHWAY | ALK2 signaling events |
0.1 | 2.0 | PID_INTEGRIN2_PATHWAY | Beta2 integrin cell surface interactions |
0.1 | 1.8 | PID_HNF3B_PATHWAY | FOXA2 and FOXA3 transcription factor networks |
0.0 | 1.7 | PID_MYC_ACTIV_PATHWAY | Validated targets of C-MYC transcriptional activation |
0.0 | 1.4 | PID_FGF_PATHWAY | FGF signaling pathway |
0.0 | 1.3 | PID_EPHA_FWDPATHWAY | EPHA forward signaling |
0.0 | 1.0 | PID_ERA_GENOMIC_PATHWAY | Validated nuclear estrogen receptor alpha network |
0.0 | 1.0 | PID_E2F_PATHWAY | E2F transcription factor network |
Gene overrepresentation in C2:CP:REACTOME category:
Showing 1 to 20 of 74 entries
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.5 | 18.4 | REACTOME_EFFECTS_OF_PIP2_HYDROLYSIS | Genes involved in Effects of PIP2 hydrolysis |
0.2 | 17.3 | REACTOME_RESPIRATORY_ELECTRON_TRANSPORT | Genes involved in Respiratory electron transport |
0.9 | 14.9 | REACTOME_GABA_A_RECEPTOR_ACTIVATION | Genes involved in GABA A receptor activation |
1.4 | 11.6 | REACTOME_TRANSPORT_OF_ORGANIC_ANIONS | Genes involved in Transport of organic anions |
0.2 | 11.4 | REACTOME_MITOCHONDRIAL_PROTEIN_IMPORT | Genes involved in Mitochondrial Protein Import |
0.9 | 10.4 | REACTOME_ADENYLATE_CYCLASE_ACTIVATING_PATHWAY | Genes involved in Adenylate cyclase activating pathway |
0.6 | 10.1 | REACTOME_FORMATION_OF_ATP_BY_CHEMIOSMOTIC_COUPLING | Genes involved in Formation of ATP by chemiosmotic coupling |
0.2 | 8.1 | REACTOME_VOLTAGE_GATED_POTASSIUM_CHANNELS | Genes involved in Voltage gated Potassium channels |
0.3 | 7.9 | REACTOME_DCC_MEDIATED_ATTRACTIVE_SIGNALING | Genes involved in DCC mediated attractive signaling |
0.2 | 7.9 | REACTOME_GLUCONEOGENESIS | Genes involved in Gluconeogenesis |
0.1 | 7.9 | REACTOME_NOTCH1_INTRACELLULAR_DOMAIN_REGULATES_TRANSCRIPTION | Genes involved in NOTCH1 Intracellular Domain Regulates Transcription |
0.5 | 6.3 | REACTOME_CLASS_C_3_METABOTROPIC_GLUTAMATE_PHEROMONE_RECEPTORS | Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors) |
0.2 | 6.3 | REACTOME_ACTIVATED_NOTCH1_TRANSMITS_SIGNAL_TO_THE_NUCLEUS | Genes involved in Activated NOTCH1 Transmits Signal to the Nucleus |
0.2 | 5.0 | REACTOME_GLYCOGEN_BREAKDOWN_GLYCOGENOLYSIS | Genes involved in Glycogen breakdown (glycogenolysis) |
0.1 | 5.0 | REACTOME_NRAGE_SIGNALS_DEATH_THROUGH_JNK | Genes involved in NRAGE signals death through JNK |
0.6 | 4.7 | REACTOME_APOBEC3G_MEDIATED_RESISTANCE_TO_HIV1_INFECTION | Genes involved in APOBEC3G mediated resistance to HIV-1 infection |
0.1 | 4.7 | REACTOME_METABOLISM_OF_VITAMINS_AND_COFACTORS | Genes involved in Metabolism of vitamins and cofactors |
0.2 | 3.9 | REACTOME_GLUTATHIONE_CONJUGATION | Genes involved in Glutathione conjugation |
0.2 | 3.7 | REACTOME_PYRUVATE_METABOLISM | Genes involved in Pyruvate metabolism |
0.2 | 3.3 | REACTOME_SIGNAL_ATTENUATION | Genes involved in Signal attenuation |