Motif ID: Etv3_Erf_Fev_Elk4_Elk1_Elk3
Z-value: 0.714
Transcription factors associated with Etv3_Erf_Fev_Elk4_Elk1_Elk3:
| Gene Symbol | Entrez ID | Gene Name |
|---|---|---|
| Elk1 | ENSMUSG00000009406.7 | Elk1 |
| Elk3 | ENSMUSG00000008398.8 | Elk3 |
| Elk4 | ENSMUSG00000026436.9 | Elk4 |
| Erf | ENSMUSG00000040857.9 | Erf |
| Etv3 | ENSMUSG00000003382.12 | Etv3 |
| Fev | ENSMUSG00000055197.4 | Fev |
Activity-expression correlation:
| Gene Symbol | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| Elk4 | mm10_v2_chr1_+_132008285_132008316 | 0.63 | 3.3e-05 | Click! |
| Etv3 | mm10_v2_chr3_+_87525572_87525643 | 0.37 | 2.6e-02 | Click! |
| Elk1 | mm10_v2_chrX_-_20950597_20950613 | 0.32 | 5.6e-02 | Click! |
| Elk3 | mm10_v2_chr10_-_93310963_93310989 | -0.19 | 2.6e-01 | Click! |
| Erf | mm10_v2_chr7_-_25250720_25250761 | 0.11 | 5.3e-01 | Click! |
Top targets:
Gene overrepresentation in biological_process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.8 | 2.4 | GO:0048611 | ectodermal digestive tract development(GO:0007439) embryonic ectodermal digestive tract development(GO:0048611) |
| 0.8 | 2.3 | GO:0019085 | early viral transcription(GO:0019085) |
| 0.7 | 0.7 | GO:0018307 | enzyme active site formation(GO:0018307) |
| 0.6 | 1.9 | GO:0043323 | positive regulation of natural killer cell degranulation(GO:0043323) |
| 0.6 | 1.8 | GO:0060003 | elastin biosynthetic process(GO:0051542) copper ion export(GO:0060003) |
| 0.6 | 1.8 | GO:1902528 | regulation of protein linear polyubiquitination(GO:1902528) positive regulation of protein linear polyubiquitination(GO:1902530) |
| 0.5 | 2.0 | GO:0002069 | columnar/cuboidal epithelial cell maturation(GO:0002069) |
| 0.5 | 2.0 | GO:0086042 | cardiac muscle cell-cardiac muscle cell adhesion(GO:0086042) |
| 0.4 | 1.8 | GO:0055071 | cellular manganese ion homeostasis(GO:0030026) Golgi calcium ion homeostasis(GO:0032468) manganese ion homeostasis(GO:0055071) |
| 0.4 | 0.9 | GO:1901668 | regulation of superoxide dismutase activity(GO:1901668) |
| 0.4 | 1.3 | GO:0006657 | CDP-choline pathway(GO:0006657) |
| 0.4 | 3.9 | GO:0099590 | neurotransmitter receptor internalization(GO:0099590) |
| 0.4 | 1.2 | GO:0036228 | protein targeting to nuclear inner membrane(GO:0036228) |
| 0.4 | 1.1 | GO:0002331 | pre-B cell allelic exclusion(GO:0002331) signal transduction involved in G2 DNA damage checkpoint(GO:0072425) signal transduction involved in mitotic G2 DNA damage checkpoint(GO:0072434) regulation of microglial cell activation(GO:1903978) telomerase catalytic core complex assembly(GO:1904868) regulation of telomerase catalytic core complex assembly(GO:1904882) positive regulation of telomerase catalytic core complex assembly(GO:1904884) |
| 0.4 | 2.3 | GO:0097680 | double-strand break repair via classical nonhomologous end joining(GO:0097680) |
| 0.4 | 1.9 | GO:0021764 | amygdala development(GO:0021764) |
| 0.3 | 1.0 | GO:0002946 | tRNA C5-cytosine methylation(GO:0002946) |
| 0.3 | 1.0 | GO:1903896 | positive regulation of IRE1-mediated unfolded protein response(GO:1903896) |
| 0.3 | 1.5 | GO:0014022 | neural plate elongation(GO:0014022) convergent extension involved in neural plate elongation(GO:0022007) |
| 0.3 | 0.9 | GO:0090004 | positive regulation of Golgi to plasma membrane protein transport(GO:0042998) positive regulation of establishment of protein localization to plasma membrane(GO:0090004) |
| 0.3 | 0.3 | GO:0048550 | negative regulation of pinocytosis(GO:0048550) |
| 0.3 | 1.1 | GO:0014042 | positive regulation of neuron maturation(GO:0014042) |
| 0.3 | 0.8 | GO:0031554 | regulation of DNA-templated transcription, termination(GO:0031554) |
| 0.2 | 0.7 | GO:2001160 | regulation of histone H3-K79 methylation(GO:2001160) |
| 0.2 | 0.7 | GO:0098974 | postsynaptic actin cytoskeleton organization(GO:0098974) |
| 0.2 | 1.0 | GO:0090365 | regulation of mRNA modification(GO:0090365) |
| 0.2 | 3.7 | GO:0060363 | cranial suture morphogenesis(GO:0060363) |
| 0.2 | 0.7 | GO:0018103 | protein C-linked glycosylation(GO:0018103) peptidyl-tryptophan modification(GO:0018211) protein C-linked glycosylation via tryptophan(GO:0018317) protein C-linked glycosylation via 2'-alpha-mannosyl-L-tryptophan(GO:0018406) |
| 0.2 | 1.6 | GO:0030242 | pexophagy(GO:0030242) |
| 0.2 | 0.4 | GO:0090071 | negative regulation of ribosome biogenesis(GO:0090071) |
| 0.2 | 0.6 | GO:0001180 | transcription initiation from RNA polymerase I promoter for nuclear large rRNA transcript(GO:0001180) |
| 0.2 | 0.6 | GO:0010636 | positive regulation of mitochondrial fusion(GO:0010636) |
| 0.2 | 0.6 | GO:0006361 | transcription initiation from RNA polymerase I promoter(GO:0006361) |
| 0.2 | 0.6 | GO:0002184 | cytoplasmic translational termination(GO:0002184) |
| 0.2 | 1.0 | GO:2000189 | positive regulation of cholesterol homeostasis(GO:2000189) |
| 0.2 | 1.0 | GO:2000825 | positive regulation of androgen receptor activity(GO:2000825) |
| 0.2 | 2.1 | GO:0097151 | positive regulation of inhibitory postsynaptic potential(GO:0097151) |
| 0.2 | 0.6 | GO:2000836 | positive regulation of androgen secretion(GO:2000836) positive regulation of testosterone secretion(GO:2000845) |
| 0.2 | 1.7 | GO:0098789 | pre-mRNA cleavage required for polyadenylation(GO:0098789) |
| 0.2 | 0.7 | GO:0021506 | anterior neuropore closure(GO:0021506) neuropore closure(GO:0021995) |
| 0.2 | 1.3 | GO:1903690 | negative regulation of wound healing, spreading of epidermal cells(GO:1903690) |
| 0.2 | 0.7 | GO:0007228 | positive regulation of hh target transcription factor activity(GO:0007228) |
| 0.2 | 1.3 | GO:0070127 | tRNA aminoacylation for mitochondrial protein translation(GO:0070127) |
| 0.2 | 1.2 | GO:1901098 | positive regulation of autophagosome maturation(GO:1901098) |
| 0.2 | 0.5 | GO:0035574 | histone H4-K20 demethylation(GO:0035574) |
| 0.2 | 0.7 | GO:0060800 | regulation of cell differentiation involved in embryonic placenta development(GO:0060800) |
| 0.2 | 0.5 | GO:0007256 | activation of JNKK activity(GO:0007256) |
| 0.2 | 0.5 | GO:0072383 | plus-end-directed vesicle transport along microtubule(GO:0072383) plus-end-directed organelle transport along microtubule(GO:0072386) |
| 0.2 | 1.5 | GO:1900262 | regulation of DNA-directed DNA polymerase activity(GO:1900262) positive regulation of DNA-directed DNA polymerase activity(GO:1900264) |
| 0.2 | 0.6 | GO:0010847 | regulation of chromatin assembly(GO:0010847) |
| 0.2 | 0.8 | GO:0015871 | astrocyte activation involved in immune response(GO:0002265) choline transport(GO:0015871) |
| 0.2 | 0.6 | GO:0019355 | nicotinamide nucleotide biosynthetic process from aspartate(GO:0019355) 'de novo' NAD biosynthetic process(GO:0034627) 'de novo' NAD biosynthetic process from aspartate(GO:0034628) |
| 0.2 | 0.6 | GO:0090309 | positive regulation of methylation-dependent chromatin silencing(GO:0090309) |
| 0.2 | 0.5 | GO:1990859 | cellular response to endothelin(GO:1990859) |
| 0.1 | 1.0 | GO:0034720 | histone H3-K4 demethylation(GO:0034720) |
| 0.1 | 0.6 | GO:0071596 | ubiquitin-dependent protein catabolic process via the N-end rule pathway(GO:0071596) |
| 0.1 | 0.4 | GO:0021691 | cerebellar Purkinje cell layer maturation(GO:0021691) |
| 0.1 | 0.6 | GO:2000211 | regulation of glutamate metabolic process(GO:2000211) |
| 0.1 | 0.4 | GO:0051771 | negative regulation of nitric-oxide synthase biosynthetic process(GO:0051771) |
| 0.1 | 1.1 | GO:0006265 | DNA topological change(GO:0006265) |
| 0.1 | 0.4 | GO:0071649 | regulation of chemokine (C-C motif) ligand 5 production(GO:0071649) |
| 0.1 | 1.2 | GO:0071420 | cellular response to histamine(GO:0071420) |
| 0.1 | 1.1 | GO:0009249 | protein lipoylation(GO:0009249) |
| 0.1 | 0.4 | GO:0071929 | alpha-tubulin acetylation(GO:0071929) |
| 0.1 | 1.2 | GO:1901409 | positive regulation of phosphorylation of RNA polymerase II C-terminal domain(GO:1901409) |
| 0.1 | 2.9 | GO:0030033 | microvillus assembly(GO:0030033) |
| 0.1 | 0.4 | GO:0036500 | ATF6-mediated unfolded protein response(GO:0036500) |
| 0.1 | 0.4 | GO:0044837 | assembly of actomyosin apparatus involved in cytokinesis(GO:0000912) actomyosin contractile ring assembly(GO:0000915) actomyosin contractile ring organization(GO:0044837) |
| 0.1 | 1.2 | GO:1903800 | positive regulation of production of miRNAs involved in gene silencing by miRNA(GO:1903800) |
| 0.1 | 1.9 | GO:0071712 | ER-associated misfolded protein catabolic process(GO:0071712) |
| 0.1 | 0.7 | GO:0090070 | positive regulation of ribosome biogenesis(GO:0090070) positive regulation of rRNA processing(GO:2000234) |
| 0.1 | 0.9 | GO:0017196 | N-terminal peptidyl-methionine acetylation(GO:0017196) |
| 0.1 | 1.0 | GO:0034498 | early endosome to Golgi transport(GO:0034498) |
| 0.1 | 0.6 | GO:0001840 | neural plate development(GO:0001840) |
| 0.1 | 1.5 | GO:0048280 | vesicle fusion with Golgi apparatus(GO:0048280) |
| 0.1 | 0.4 | GO:0097278 | transforming growth factor beta activation(GO:0036363) complement-dependent cytotoxicity(GO:0097278) |
| 0.1 | 0.3 | GO:2000686 | regulation of rubidium ion transmembrane transporter activity(GO:2000686) |
| 0.1 | 0.5 | GO:0046619 | optic placode formation involved in camera-type eye formation(GO:0046619) |
| 0.1 | 1.7 | GO:0003283 | atrial septum development(GO:0003283) |
| 0.1 | 0.1 | GO:0016572 | histone phosphorylation(GO:0016572) |
| 0.1 | 0.1 | GO:0099500 | synaptic vesicle fusion to presynaptic active zone membrane(GO:0031629) vesicle fusion to plasma membrane(GO:0099500) |
| 0.1 | 0.3 | GO:0051533 | positive regulation of NFAT protein import into nucleus(GO:0051533) |
| 0.1 | 0.5 | GO:0070164 | negative regulation of adiponectin secretion(GO:0070164) |
| 0.1 | 0.5 | GO:0006543 | glutamine catabolic process(GO:0006543) |
| 0.1 | 0.2 | GO:1902915 | negative regulation of protein K63-linked ubiquitination(GO:1900045) negative regulation of protein polyubiquitination(GO:1902915) |
| 0.1 | 0.6 | GO:0044375 | regulation of peroxisome size(GO:0044375) |
| 0.1 | 2.1 | GO:0036295 | cellular response to increased oxygen levels(GO:0036295) |
| 0.1 | 0.4 | GO:0035624 | mast cell homeostasis(GO:0033023) mast cell apoptotic process(GO:0033024) regulation of mast cell apoptotic process(GO:0033025) receptor transactivation(GO:0035624) epidermal growth factor-activated receptor transactivation by G-protein coupled receptor signaling pathway(GO:0035625) response to high density lipoprotein particle(GO:0055099) |
| 0.1 | 0.6 | GO:0070827 | chromatin maintenance(GO:0070827) |
| 0.1 | 0.4 | GO:0044253 | positive regulation of collagen metabolic process(GO:0010714) positive regulation of collagen biosynthetic process(GO:0032967) positive regulation of multicellular organismal metabolic process(GO:0044253) |
| 0.1 | 0.3 | GO:0048162 | preantral ovarian follicle growth(GO:0001546) multi-layer follicle stage(GO:0048162) |
| 0.1 | 0.4 | GO:0030043 | actin filament fragmentation(GO:0030043) |
| 0.1 | 1.4 | GO:0033234 | negative regulation of protein sumoylation(GO:0033234) |
| 0.1 | 1.0 | GO:0018342 | protein prenylation(GO:0018342) prenylation(GO:0097354) |
| 0.1 | 1.3 | GO:0006266 | DNA ligation(GO:0006266) |
| 0.1 | 1.1 | GO:0099628 | receptor diffusion trapping(GO:0098953) postsynaptic neurotransmitter receptor diffusion trapping(GO:0098970) neurotransmitter receptor diffusion trapping(GO:0099628) |
| 0.1 | 1.1 | GO:0030157 | pancreatic juice secretion(GO:0030157) |
| 0.1 | 0.4 | GO:0000393 | spliceosomal conformational changes to generate catalytic conformation(GO:0000393) |
| 0.1 | 0.5 | GO:1903012 | positive regulation of bone development(GO:1903012) |
| 0.1 | 0.4 | GO:0061010 | gall bladder development(GO:0061010) |
| 0.1 | 0.3 | GO:0006030 | chitin metabolic process(GO:0006030) chitin catabolic process(GO:0006032) |
| 0.1 | 0.3 | GO:0070125 | mitochondrial translational elongation(GO:0070125) |
| 0.1 | 0.3 | GO:0060399 | positive regulation of growth hormone receptor signaling pathway(GO:0060399) |
| 0.1 | 0.5 | GO:1900246 | positive regulation of RIG-I signaling pathway(GO:1900246) |
| 0.1 | 1.9 | GO:0002076 | osteoblast development(GO:0002076) |
| 0.1 | 0.4 | GO:1904690 | adenosine to inosine editing(GO:0006382) regulation of cap-independent translational initiation(GO:1903677) positive regulation of cap-independent translational initiation(GO:1903679) regulation of cytoplasmic translational initiation(GO:1904688) positive regulation of cytoplasmic translational initiation(GO:1904690) |
| 0.1 | 0.3 | GO:0016344 | meiotic chromosome movement towards spindle pole(GO:0016344) |
| 0.1 | 0.2 | GO:0000389 | mRNA 3'-splice site recognition(GO:0000389) |
| 0.1 | 1.2 | GO:2001256 | regulation of store-operated calcium entry(GO:2001256) |
| 0.1 | 0.6 | GO:0030950 | establishment or maintenance of actin cytoskeleton polarity(GO:0030950) |
| 0.1 | 0.6 | GO:0031642 | negative regulation of myelination(GO:0031642) |
| 0.1 | 0.3 | GO:0071105 | response to interleukin-11(GO:0071105) |
| 0.1 | 0.3 | GO:0032053 | ciliary basal body organization(GO:0032053) |
| 0.1 | 0.5 | GO:1990009 | retinal cell apoptotic process(GO:1990009) |
| 0.1 | 0.5 | GO:0018022 | peptidyl-lysine methylation(GO:0018022) |
| 0.1 | 0.3 | GO:0071883 | activation of MAPK activity by adrenergic receptor signaling pathway(GO:0071883) |
| 0.1 | 0.2 | GO:0097155 | fasciculation of sensory neuron axon(GO:0097155) |
| 0.1 | 0.4 | GO:0060050 | positive regulation of protein glycosylation(GO:0060050) |
| 0.1 | 3.4 | GO:0045761 | regulation of adenylate cyclase activity(GO:0045761) |
| 0.1 | 0.4 | GO:0036258 | multivesicular body organization(GO:0036257) multivesicular body assembly(GO:0036258) |
| 0.1 | 0.4 | GO:0036438 | maintenance of lens transparency(GO:0036438) |
| 0.1 | 0.3 | GO:0019323 | pentose catabolic process(GO:0019323) |
| 0.1 | 2.5 | GO:0006829 | zinc II ion transport(GO:0006829) |
| 0.1 | 0.3 | GO:0006049 | UDP-N-acetylglucosamine catabolic process(GO:0006049) |
| 0.1 | 1.4 | GO:0034389 | lipid particle organization(GO:0034389) |
| 0.1 | 0.6 | GO:0000055 | ribosomal large subunit export from nucleus(GO:0000055) |
| 0.1 | 0.8 | GO:0000244 | spliceosomal tri-snRNP complex assembly(GO:0000244) |
| 0.1 | 0.7 | GO:0000290 | deadenylation-dependent decapping of nuclear-transcribed mRNA(GO:0000290) |
| 0.1 | 0.3 | GO:0018202 | peptidyl-histidine modification(GO:0018202) |
| 0.1 | 1.0 | GO:0007250 | activation of NF-kappaB-inducing kinase activity(GO:0007250) |
| 0.1 | 0.3 | GO:1902626 | assembly of large subunit precursor of preribosome(GO:1902626) |
| 0.1 | 0.1 | GO:0061744 | motor behavior(GO:0061744) |
| 0.1 | 0.2 | GO:0000973 | posttranscriptional tethering of RNA polymerase II gene DNA at nuclear periphery(GO:0000973) |
| 0.1 | 0.2 | GO:0070535 | histone H2A K63-linked ubiquitination(GO:0070535) |
| 0.1 | 0.1 | GO:2000812 | regulation of barbed-end actin filament capping(GO:2000812) |
| 0.1 | 0.4 | GO:1903056 | positive regulation of lens fiber cell differentiation(GO:1902748) regulation of melanosome organization(GO:1903056) |
| 0.1 | 0.5 | GO:0051418 | interphase microtubule nucleation by interphase microtubule organizing center(GO:0051415) microtubule nucleation by microtubule organizing center(GO:0051418) |
| 0.1 | 0.6 | GO:0006686 | sphingomyelin biosynthetic process(GO:0006686) |
| 0.1 | 0.7 | GO:0035562 | negative regulation of chromatin binding(GO:0035562) |
| 0.1 | 0.7 | GO:0061470 | interleukin-21 production(GO:0032625) T follicular helper cell differentiation(GO:0061470) interleukin-21 secretion(GO:0072619) |
| 0.1 | 1.5 | GO:0051654 | establishment of mitochondrion localization(GO:0051654) |
| 0.1 | 0.5 | GO:0032471 | negative regulation of endoplasmic reticulum calcium ion concentration(GO:0032471) |
| 0.1 | 0.6 | GO:0070940 | dephosphorylation of RNA polymerase II C-terminal domain(GO:0070940) |
| 0.1 | 0.3 | GO:0044314 | protein K27-linked ubiquitination(GO:0044314) |
| 0.1 | 0.5 | GO:0031848 | protection from non-homologous end joining at telomere(GO:0031848) |
| 0.1 | 0.6 | GO:0031937 | positive regulation of chromatin silencing(GO:0031937) |
| 0.1 | 0.3 | GO:0010724 | regulation of definitive erythrocyte differentiation(GO:0010724) |
| 0.1 | 0.4 | GO:0046007 | negative regulation of activated T cell proliferation(GO:0046007) |
| 0.1 | 0.2 | GO:0040010 | positive regulation of growth rate(GO:0040010) |
| 0.1 | 0.7 | GO:0045947 | negative regulation of translational initiation(GO:0045947) |
| 0.1 | 0.3 | GO:0010025 | wax biosynthetic process(GO:0010025) wax metabolic process(GO:0010166) |
| 0.1 | 0.5 | GO:0048102 | autophagic cell death(GO:0048102) |
| 0.1 | 0.1 | GO:0002831 | regulation of response to biotic stimulus(GO:0002831) |
| 0.1 | 0.1 | GO:0000054 | ribosomal subunit export from nucleus(GO:0000054) ribosome localization(GO:0033750) establishment of ribosome localization(GO:0033753) |
| 0.1 | 0.2 | GO:1903265 | positive regulation of tumor necrosis factor-mediated signaling pathway(GO:1903265) |
| 0.1 | 0.2 | GO:0006776 | vitamin A metabolic process(GO:0006776) positive regulation of skeletal muscle tissue regeneration(GO:0043415) |
| 0.1 | 0.2 | GO:0030200 | heparan sulfate proteoglycan catabolic process(GO:0030200) |
| 0.1 | 0.2 | GO:0006436 | tryptophanyl-tRNA aminoacylation(GO:0006436) |
| 0.1 | 0.4 | GO:1904217 | regulation of CDP-diacylglycerol-serine O-phosphatidyltransferase activity(GO:1904217) positive regulation of CDP-diacylglycerol-serine O-phosphatidyltransferase activity(GO:1904219) regulation of serine C-palmitoyltransferase activity(GO:1904220) positive regulation of serine C-palmitoyltransferase activity(GO:1904222) |
| 0.1 | 0.2 | GO:0038108 | negative regulation of appetite by leptin-mediated signaling pathway(GO:0038108) |
| 0.1 | 0.8 | GO:0006338 | chromatin remodeling(GO:0006338) |
| 0.1 | 0.3 | GO:0034058 | endosomal vesicle fusion(GO:0034058) |
| 0.1 | 0.6 | GO:0090110 | cargo loading into COPII-coated vesicle(GO:0090110) |
| 0.1 | 0.5 | GO:0019511 | peptidyl-proline hydroxylation(GO:0019511) |
| 0.1 | 0.2 | GO:0046898 | response to cycloheximide(GO:0046898) |
| 0.1 | 0.3 | GO:1904953 | Wnt signaling pathway involved in midbrain dopaminergic neuron differentiation(GO:1904953) |
| 0.1 | 0.2 | GO:0001828 | inner cell mass cell fate commitment(GO:0001827) inner cell mass cellular morphogenesis(GO:0001828) |
| 0.1 | 0.3 | GO:1900095 | regulation of dosage compensation by inactivation of X chromosome(GO:1900095) |
| 0.1 | 0.9 | GO:0035721 | intraciliary retrograde transport(GO:0035721) |
| 0.1 | 0.1 | GO:1902410 | mitotic cytokinetic process(GO:1902410) |
| 0.0 | 0.3 | GO:1902741 | type I interferon secretion(GO:0072641) interferon-alpha secretion(GO:0072642) regulation of interferon-alpha secretion(GO:1902739) positive regulation of interferon-alpha secretion(GO:1902741) |
| 0.0 | 0.2 | GO:0044782 | cilium organization(GO:0044782) |
| 0.0 | 0.4 | GO:0016576 | histone dephosphorylation(GO:0016576) |
| 0.0 | 1.4 | GO:2000369 | regulation of clathrin-mediated endocytosis(GO:2000369) |
| 0.0 | 0.4 | GO:0006544 | glycine metabolic process(GO:0006544) |
| 0.0 | 0.3 | GO:0016266 | O-glycan processing(GO:0016266) |
| 0.0 | 0.1 | GO:0002034 | angiotensin mediated vasoconstriction involved in regulation of systemic arterial blood pressure(GO:0001998) regulation of blood vessel size by renin-angiotensin(GO:0002034) renal control of peripheral vascular resistance involved in regulation of systemic arterial blood pressure(GO:0003072) |
| 0.0 | 1.0 | GO:0008209 | androgen metabolic process(GO:0008209) |
| 0.0 | 0.1 | GO:0015793 | glycerol transport(GO:0015793) response to oxygen-glucose deprivation(GO:0090649) cellular response to oxygen-glucose deprivation(GO:0090650) |
| 0.0 | 0.1 | GO:0061357 | Wnt protein secretion(GO:0061355) regulation of Wnt protein secretion(GO:0061356) positive regulation of Wnt protein secretion(GO:0061357) |
| 0.0 | 0.2 | GO:1904587 | protein deglycosylation involved in glycoprotein catabolic process(GO:0035977) protein demannosylation(GO:0036507) protein alpha-1,2-demannosylation(GO:0036508) glycoprotein ERAD pathway(GO:0097466) mannose trimming involved in glycoprotein ERAD pathway(GO:1904382) response to glycoprotein(GO:1904587) |
| 0.0 | 0.9 | GO:0007020 | microtubule nucleation(GO:0007020) |
| 0.0 | 0.1 | GO:0045359 | positive regulation of interferon-beta biosynthetic process(GO:0045359) |
| 0.0 | 0.1 | GO:0072720 | response to sorbitol(GO:0072708) response to dithiothreitol(GO:0072720) |
| 0.0 | 0.2 | GO:0098543 | detection of bacterium(GO:0016045) detection of other organism(GO:0098543) |
| 0.0 | 0.2 | GO:0018095 | protein polyglutamylation(GO:0018095) |
| 0.0 | 0.2 | GO:0006384 | transcription initiation from RNA polymerase III promoter(GO:0006384) |
| 0.0 | 0.3 | GO:1901844 | regulation of cell communication by electrical coupling involved in cardiac conduction(GO:1901844) |
| 0.0 | 0.1 | GO:0048298 | positive regulation of isotype switching to IgA isotypes(GO:0048298) |
| 0.0 | 0.6 | GO:0006878 | cellular copper ion homeostasis(GO:0006878) |
| 0.0 | 0.6 | GO:0016973 | poly(A)+ mRNA export from nucleus(GO:0016973) |
| 0.0 | 0.1 | GO:1903903 | regulation of establishment of T cell polarity(GO:1903903) |
| 0.0 | 0.3 | GO:1900017 | positive regulation of cytokine production involved in inflammatory response(GO:1900017) |
| 0.0 | 0.0 | GO:0007290 | spermatid nucleus elongation(GO:0007290) |
| 0.0 | 0.5 | GO:0070932 | histone H3 deacetylation(GO:0070932) |
| 0.0 | 1.4 | GO:0045197 | establishment or maintenance of epithelial cell apical/basal polarity(GO:0045197) |
| 0.0 | 0.4 | GO:1903351 | response to dopamine(GO:1903350) cellular response to dopamine(GO:1903351) |
| 0.0 | 0.4 | GO:1904153 | negative regulation of protein exit from endoplasmic reticulum(GO:0070862) negative regulation of retrograde protein transport, ER to cytosol(GO:1904153) |
| 0.0 | 0.2 | GO:0090267 | positive regulation of mitotic cell cycle spindle assembly checkpoint(GO:0090267) |
| 0.0 | 1.2 | GO:0070979 | protein K11-linked ubiquitination(GO:0070979) |
| 0.0 | 0.3 | GO:0070423 | nucleotide-binding oligomerization domain containing signaling pathway(GO:0070423) nucleotide-binding oligomerization domain containing 2 signaling pathway(GO:0070431) |
| 0.0 | 0.4 | GO:0090385 | phagosome-lysosome fusion(GO:0090385) |
| 0.0 | 0.1 | GO:0006106 | fumarate metabolic process(GO:0006106) aspartate biosynthetic process(GO:0006532) aspartate catabolic process(GO:0006533) alditol biosynthetic process(GO:0019401) |
| 0.0 | 0.0 | GO:1903371 | regulation of endoplasmic reticulum tubular network organization(GO:1903371) |
| 0.0 | 0.1 | GO:1903538 | meiotic sister chromatid cohesion, centromeric(GO:0051754) meiotic cell cycle process involved in oocyte maturation(GO:1903537) regulation of meiotic cell cycle process involved in oocyte maturation(GO:1903538) |
| 0.0 | 1.6 | GO:0030521 | androgen receptor signaling pathway(GO:0030521) |
| 0.0 | 0.4 | GO:0035646 | endosome to melanosome transport(GO:0035646) endosome to pigment granule transport(GO:0043485) pigment granule maturation(GO:0048757) |
| 0.0 | 0.5 | GO:0045974 | miRNA mediated inhibition of translation(GO:0035278) negative regulation of translation, ncRNA-mediated(GO:0040033) regulation of translation, ncRNA-mediated(GO:0045974) |
| 0.0 | 0.3 | GO:0010032 | meiotic chromosome condensation(GO:0010032) |
| 0.0 | 0.2 | GO:0071894 | histone H2B conserved C-terminal lysine ubiquitination(GO:0071894) |
| 0.0 | 0.3 | GO:0002903 | negative regulation of B cell apoptotic process(GO:0002903) |
| 0.0 | 0.2 | GO:0045347 | negative regulation of MHC class II biosynthetic process(GO:0045347) |
| 0.0 | 0.1 | GO:0070863 | positive regulation of protein exit from endoplasmic reticulum(GO:0070863) |
| 0.0 | 0.1 | GO:0035507 | regulation of myosin-light-chain-phosphatase activity(GO:0035507) |
| 0.0 | 0.3 | GO:0006268 | DNA unwinding involved in DNA replication(GO:0006268) |
| 0.0 | 0.1 | GO:0046501 | protoporphyrinogen IX metabolic process(GO:0046501) |
| 0.0 | 0.1 | GO:0034983 | peptidyl-lysine deacetylation(GO:0034983) |
| 0.0 | 0.1 | GO:0097039 | protein linear polyubiquitination(GO:0097039) |
| 0.0 | 0.1 | GO:1901978 | positive regulation of cell cycle checkpoint(GO:1901978) |
| 0.0 | 0.3 | GO:0021942 | radial glia guided migration of Purkinje cell(GO:0021942) |
| 0.0 | 0.2 | GO:0032055 | negative regulation of translation in response to stress(GO:0032055) positive regulation of type B pancreatic cell apoptotic process(GO:2000676) |
| 0.0 | 0.1 | GO:0016240 | autophagosome docking(GO:0016240) |
| 0.0 | 0.1 | GO:0009212 | dTTP biosynthetic process(GO:0006235) pyrimidine deoxyribonucleoside triphosphate biosynthetic process(GO:0009212) dTTP metabolic process(GO:0046075) |
| 0.0 | 0.8 | GO:0061512 | protein localization to cilium(GO:0061512) |
| 0.0 | 0.1 | GO:0031860 | telomeric 3' overhang formation(GO:0031860) |
| 0.0 | 0.6 | GO:0051457 | maintenance of protein location in nucleus(GO:0051457) |
| 0.0 | 0.2 | GO:1903223 | positive regulation of oxidative stress-induced neuron death(GO:1903223) positive regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway(GO:1903378) |
| 0.0 | 0.3 | GO:0051560 | mitochondrial calcium ion homeostasis(GO:0051560) |
| 0.0 | 0.1 | GO:0010499 | proteasomal ubiquitin-independent protein catabolic process(GO:0010499) |
| 0.0 | 0.2 | GO:0060046 | regulation of acrosome reaction(GO:0060046) |
| 0.0 | 0.1 | GO:0070488 | regulation of integrin biosynthetic process(GO:0045113) neutrophil aggregation(GO:0070488) |
| 0.0 | 0.1 | GO:0090234 | regulation of kinetochore assembly(GO:0090234) |
| 0.0 | 0.4 | GO:0090161 | Golgi ribbon formation(GO:0090161) |
| 0.0 | 0.2 | GO:2000601 | positive regulation of Arp2/3 complex-mediated actin nucleation(GO:2000601) |
| 0.0 | 0.1 | GO:0046599 | regulation of centriole replication(GO:0046599) |
| 0.0 | 0.4 | GO:0048642 | negative regulation of skeletal muscle tissue development(GO:0048642) |
| 0.0 | 0.5 | GO:0051131 | chaperone-mediated protein complex assembly(GO:0051131) |
| 0.0 | 1.9 | GO:0010923 | negative regulation of phosphatase activity(GO:0010923) |
| 0.0 | 0.2 | GO:0051014 | actin filament severing(GO:0051014) |
| 0.0 | 1.0 | GO:0006890 | retrograde vesicle-mediated transport, Golgi to ER(GO:0006890) |
| 0.0 | 0.1 | GO:0046881 | sperm ejaculation(GO:0042713) positive regulation of follicle-stimulating hormone secretion(GO:0046881) Sertoli cell proliferation(GO:0060011) |
| 0.0 | 0.2 | GO:0016558 | protein import into peroxisome matrix(GO:0016558) |
| 0.0 | 0.4 | GO:0010225 | response to UV-C(GO:0010225) |
| 0.0 | 0.2 | GO:0036444 | calcium ion transmembrane import into mitochondrion(GO:0036444) |
| 0.0 | 0.4 | GO:0032968 | positive regulation of transcription elongation from RNA polymerase II promoter(GO:0032968) |
| 0.0 | 0.1 | GO:0035331 | negative regulation of hippo signaling(GO:0035331) |
| 0.0 | 0.5 | GO:0048268 | clathrin coat assembly(GO:0048268) |
| 0.0 | 0.3 | GO:0045725 | positive regulation of glycogen biosynthetic process(GO:0045725) |
| 0.0 | 0.5 | GO:0048820 | hair follicle maturation(GO:0048820) |
| 0.0 | 0.9 | GO:0045668 | negative regulation of osteoblast differentiation(GO:0045668) |
| 0.0 | 0.1 | GO:0036066 | protein O-linked fucosylation(GO:0036066) |
| 0.0 | 1.3 | GO:0051865 | protein autoubiquitination(GO:0051865) |
| 0.0 | 0.1 | GO:0010793 | regulation of mRNA export from nucleus(GO:0010793) regulation of ribonucleoprotein complex localization(GO:2000197) |
| 0.0 | 0.9 | GO:0006360 | transcription from RNA polymerase I promoter(GO:0006360) |
| 0.0 | 0.2 | GO:0060712 | spongiotrophoblast layer development(GO:0060712) |
| 0.0 | 0.1 | GO:0098887 | neurotransmitter receptor transport, endosome to postsynaptic membrane(GO:0098887) endosome to plasma membrane protein transport(GO:0099638) neurotransmitter receptor transport, endosome to plasma membrane(GO:0099639) |
| 0.0 | 0.3 | GO:0006614 | SRP-dependent cotranslational protein targeting to membrane(GO:0006614) |
| 0.0 | 0.1 | GO:0051892 | regulation of cardioblast differentiation(GO:0051890) negative regulation of cardioblast differentiation(GO:0051892) |
| 0.0 | 0.9 | GO:0000266 | mitochondrial fission(GO:0000266) |
| 0.0 | 0.1 | GO:0070889 | platelet alpha granule organization(GO:0070889) |
| 0.0 | 0.1 | GO:0031335 | regulation of sulfur amino acid metabolic process(GO:0031335) |
| 0.0 | 0.3 | GO:0006378 | mRNA polyadenylation(GO:0006378) |
| 0.0 | 0.8 | GO:0006376 | mRNA splice site selection(GO:0006376) |
| 0.0 | 0.4 | GO:0035308 | negative regulation of protein dephosphorylation(GO:0035308) |
| 0.0 | 0.8 | GO:2000036 | regulation of stem cell population maintenance(GO:2000036) |
| 0.0 | 0.1 | GO:2000049 | positive regulation of cell-cell adhesion mediated by cadherin(GO:2000049) |
| 0.0 | 0.1 | GO:1900748 | positive regulation of vascular endothelial growth factor signaling pathway(GO:1900748) |
| 0.0 | 0.5 | GO:0000027 | ribosomal large subunit assembly(GO:0000027) |
| 0.0 | 0.2 | GO:0001675 | acrosome assembly(GO:0001675) |
| 0.0 | 0.1 | GO:0006680 | glucosylceramide catabolic process(GO:0006680) |
| 0.0 | 0.1 | GO:0051088 | PMA-inducible membrane protein ectodomain proteolysis(GO:0051088) |
| 0.0 | 0.1 | GO:0006409 | tRNA export from nucleus(GO:0006409) tRNA-containing ribonucleoprotein complex export from nucleus(GO:0071431) |
| 0.0 | 0.1 | GO:0061739 | protein lipidation involved in autophagosome assembly(GO:0061739) |
| 0.0 | 0.1 | GO:0090325 | regulation of locomotion involved in locomotory behavior(GO:0090325) negative regulation of locomotion involved in locomotory behavior(GO:0090327) |
| 0.0 | 0.4 | GO:2000300 | regulation of synaptic vesicle exocytosis(GO:2000300) |
| 0.0 | 0.2 | GO:0034629 | cellular protein complex localization(GO:0034629) |
| 0.0 | 0.2 | GO:0006370 | 7-methylguanosine mRNA capping(GO:0006370) |
| 0.0 | 0.9 | GO:0006893 | Golgi to plasma membrane transport(GO:0006893) |
| 0.0 | 0.1 | GO:0019046 | release from viral latency(GO:0019046) |
| 0.0 | 0.1 | GO:0010992 | ubiquitin homeostasis(GO:0010992) |
| 0.0 | 0.1 | GO:0090043 | tubulin deacetylation(GO:0090042) regulation of tubulin deacetylation(GO:0090043) |
| 0.0 | 0.3 | GO:0033539 | fatty acid beta-oxidation using acyl-CoA dehydrogenase(GO:0033539) |
| 0.0 | 0.1 | GO:1903146 | regulation of mitophagy(GO:1903146) |
| 0.0 | 0.1 | GO:0034454 | microtubule anchoring at centrosome(GO:0034454) |
| 0.0 | 0.1 | GO:2000623 | regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000622) negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000623) |
| 0.0 | 0.0 | GO:0060339 | negative regulation of type I interferon-mediated signaling pathway(GO:0060339) |
| 0.0 | 2.3 | GO:0000209 | protein polyubiquitination(GO:0000209) |
| 0.0 | 0.2 | GO:0002091 | negative regulation of receptor internalization(GO:0002091) |
| 0.0 | 0.1 | GO:0032308 | positive regulation of prostaglandin secretion(GO:0032308) |
| 0.0 | 0.1 | GO:0006983 | ER overload response(GO:0006983) |
| 0.0 | 0.6 | GO:0006879 | cellular iron ion homeostasis(GO:0006879) |
| 0.0 | 0.2 | GO:0051601 | exocyst localization(GO:0051601) |
| 0.0 | 0.3 | GO:0000245 | spliceosomal complex assembly(GO:0000245) |
| 0.0 | 0.3 | GO:0097034 | mitochondrial respiratory chain complex IV assembly(GO:0033617) mitochondrial respiratory chain complex IV biogenesis(GO:0097034) |
| 0.0 | 0.0 | GO:0002329 | pre-B cell differentiation(GO:0002329) |
| 0.0 | 0.2 | GO:0051683 | establishment of Golgi localization(GO:0051683) |
| 0.0 | 0.1 | GO:0000722 | telomere maintenance via recombination(GO:0000722) |
| 0.0 | 0.1 | GO:0051045 | negative regulation of membrane protein ectodomain proteolysis(GO:0051045) |
| 0.0 | 0.1 | GO:0006515 | misfolded or incompletely synthesized protein catabolic process(GO:0006515) |
| 0.0 | 0.3 | GO:0006744 | ubiquinone biosynthetic process(GO:0006744) |
| 0.0 | 0.2 | GO:0035563 | positive regulation of chromatin binding(GO:0035563) |
| 0.0 | 0.2 | GO:0030213 | hyaluronan biosynthetic process(GO:0030213) |
| 0.0 | 0.0 | GO:0043552 | positive regulation of phosphatidylinositol 3-kinase activity(GO:0043552) |
| 0.0 | 0.1 | GO:0080009 | mRNA methylation(GO:0080009) |
| 0.0 | 0.1 | GO:0033313 | meiotic cell cycle checkpoint(GO:0033313) |
| 0.0 | 0.1 | GO:0061084 | regulation of protein refolding(GO:0061083) negative regulation of protein refolding(GO:0061084) |
| 0.0 | 0.0 | GO:1904719 | excitatory chemical synaptic transmission(GO:0098976) positive regulation of AMPA glutamate receptor clustering(GO:1904719) |
| 0.0 | 0.1 | GO:0034551 | respiratory chain complex III assembly(GO:0017062) mitochondrial respiratory chain complex III assembly(GO:0034551) mitochondrial respiratory chain complex III biogenesis(GO:0097033) |
| 0.0 | 0.2 | GO:0006622 | protein targeting to lysosome(GO:0006622) |
| 0.0 | 0.2 | GO:2000009 | negative regulation of protein localization to cell surface(GO:2000009) |
| 0.0 | 0.1 | GO:0044110 | growth involved in symbiotic interaction(GO:0044110) growth of symbiont involved in interaction with host(GO:0044116) growth of symbiont in host(GO:0044117) regulation of growth of symbiont in host(GO:0044126) modulation of growth of symbiont involved in interaction with host(GO:0044144) |
| 0.0 | 0.1 | GO:0030223 | neutrophil differentiation(GO:0030223) |
| 0.0 | 0.1 | GO:0006481 | C-terminal protein methylation(GO:0006481) |
| 0.0 | 0.0 | GO:0010757 | negative regulation of plasminogen activation(GO:0010757) |
| 0.0 | 0.0 | GO:0016561 | protein import into peroxisome matrix, translocation(GO:0016561) |
| 0.0 | 0.7 | GO:0042147 | retrograde transport, endosome to Golgi(GO:0042147) |
| 0.0 | 0.3 | GO:0051043 | regulation of membrane protein ectodomain proteolysis(GO:0051043) positive regulation of membrane protein ectodomain proteolysis(GO:0051044) |
| 0.0 | 0.2 | GO:0060059 | embryonic retina morphogenesis in camera-type eye(GO:0060059) |
| 0.0 | 0.1 | GO:1990440 | positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress(GO:1990440) |
| 0.0 | 0.1 | GO:0007252 | I-kappaB phosphorylation(GO:0007252) |
| 0.0 | 0.1 | GO:0060539 | diaphragm development(GO:0060539) |
| 0.0 | 0.0 | GO:0071033 | nuclear retention of pre-mRNA at the site of transcription(GO:0071033) |
| 0.0 | 0.2 | GO:0071480 | cellular response to gamma radiation(GO:0071480) |
| 0.0 | 0.2 | GO:0072520 | seminiferous tubule development(GO:0072520) |
| 0.0 | 0.1 | GO:0031424 | keratinization(GO:0031424) |
| 0.0 | 0.1 | GO:2000507 | positive regulation of energy homeostasis(GO:2000507) |
| 0.0 | 0.0 | GO:0071638 | monocyte chemotactic protein-1 production(GO:0071605) regulation of monocyte chemotactic protein-1 production(GO:0071637) negative regulation of monocyte chemotactic protein-1 production(GO:0071638) |
| 0.0 | 0.1 | GO:0006172 | ADP biosynthetic process(GO:0006172) |
| 0.0 | 0.0 | GO:0006297 | nucleotide-excision repair, DNA gap filling(GO:0006297) |
| 0.0 | 0.1 | GO:0006272 | DNA replication, synthesis of RNA primer(GO:0006269) leading strand elongation(GO:0006272) |
| 0.0 | 0.5 | GO:0046825 | regulation of protein export from nucleus(GO:0046825) |
| 0.0 | 0.1 | GO:0008340 | determination of adult lifespan(GO:0008340) |
| 0.0 | 0.0 | GO:0001672 | regulation of chromatin assembly or disassembly(GO:0001672) |
| 0.0 | 0.1 | GO:0034315 | regulation of Arp2/3 complex-mediated actin nucleation(GO:0034315) |
| 0.0 | 0.0 | GO:0008612 | peptidyl-lysine modification to peptidyl-hypusine(GO:0008612) |
| 0.0 | 1.0 | GO:0042787 | protein ubiquitination involved in ubiquitin-dependent protein catabolic process(GO:0042787) |
| 0.0 | 0.0 | GO:0006701 | progesterone biosynthetic process(GO:0006701) |
| 0.0 | 0.1 | GO:0006353 | DNA-templated transcription, termination(GO:0006353) |
| 0.0 | 0.1 | GO:0001783 | B cell apoptotic process(GO:0001783) |
| 0.0 | 0.1 | GO:0046580 | negative regulation of Ras protein signal transduction(GO:0046580) negative regulation of small GTPase mediated signal transduction(GO:0051058) |
| 0.0 | 0.0 | GO:0055005 | ventricular cardiac myofibril assembly(GO:0055005) |
| 0.0 | 0.0 | GO:0006287 | base-excision repair, gap-filling(GO:0006287) |
| 0.0 | 0.2 | GO:0046325 | negative regulation of glucose import(GO:0046325) |
| 0.0 | 0.1 | GO:0043313 | regulation of neutrophil degranulation(GO:0043313) |
| 0.0 | 0.0 | GO:0061718 | NADH regeneration(GO:0006735) canonical glycolysis(GO:0061621) glucose catabolic process to pyruvate(GO:0061718) |
| 0.0 | 0.8 | GO:0035725 | sodium ion transmembrane transport(GO:0035725) |
| 0.0 | 0.3 | GO:2000311 | regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity(GO:2000311) |
| 0.0 | 0.1 | GO:0000185 | activation of MAPKKK activity(GO:0000185) |
| 0.0 | 0.0 | GO:0040016 | embryonic cleavage(GO:0040016) |
| 0.0 | 0.1 | GO:0051352 | negative regulation of ligase activity(GO:0051352) negative regulation of ubiquitin-protein transferase activity(GO:0051444) |
| 0.0 | 0.1 | GO:0010457 | centriole-centriole cohesion(GO:0010457) |
| 0.0 | 0.1 | GO:1901621 | negative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning(GO:1901621) |
| 0.0 | 0.0 | GO:0018242 | protein O-linked glycosylation via serine(GO:0018242) |
| 0.0 | 0.2 | GO:0030968 | endoplasmic reticulum unfolded protein response(GO:0030968) |
| 0.0 | 0.2 | GO:0006379 | mRNA cleavage(GO:0006379) |
| 0.0 | 0.1 | GO:0032380 | regulation of intracellular lipid transport(GO:0032377) regulation of intracellular sterol transport(GO:0032380) regulation of intracellular cholesterol transport(GO:0032383) |
| 0.0 | 0.1 | GO:0044387 | negative regulation of protein kinase activity by regulation of protein phosphorylation(GO:0044387) |
| 0.0 | 0.3 | GO:0046326 | positive regulation of glucose import(GO:0046326) |
| 0.0 | 0.0 | GO:0002101 | tRNA wobble cytosine modification(GO:0002101) |
| 0.0 | 0.0 | GO:0002191 | cap-dependent translational initiation(GO:0002191) |
| 0.0 | 0.3 | GO:0018345 | protein palmitoylation(GO:0018345) |
| 0.0 | 2.1 | GO:0046777 | protein autophosphorylation(GO:0046777) |
Gene overrepresentation in cellular_component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.6 | 2.8 | GO:1990745 | EARP complex(GO:1990745) |
| 0.5 | 3.7 | GO:0032937 | SREBP-SCAP-Insig complex(GO:0032937) |
| 0.4 | 2.5 | GO:0005958 | DNA-dependent protein kinase-DNA ligase 4 complex(GO:0005958) DNA ligase IV complex(GO:0032807) |
| 0.4 | 1.3 | GO:0071920 | cleavage body(GO:0071920) |
| 0.3 | 1.3 | GO:0030981 | cortical microtubule cytoskeleton(GO:0030981) |
| 0.3 | 0.9 | GO:0070985 | TFIIK complex(GO:0070985) |
| 0.3 | 1.5 | GO:0090498 | extrinsic component of Golgi membrane(GO:0090498) |
| 0.3 | 1.7 | GO:0070847 | core mediator complex(GO:0070847) |
| 0.3 | 0.3 | GO:0000346 | transcription export complex(GO:0000346) |
| 0.2 | 2.2 | GO:0033180 | proton-transporting V-type ATPase, V1 domain(GO:0033180) |
| 0.2 | 1.9 | GO:0097427 | microtubule bundle(GO:0097427) |
| 0.2 | 0.6 | GO:0030130 | clathrin coat of trans-Golgi network vesicle(GO:0030130) |
| 0.2 | 0.6 | GO:0018444 | translation release factor complex(GO:0018444) |
| 0.2 | 0.6 | GO:0000799 | nuclear condensin complex(GO:0000799) |
| 0.2 | 1.8 | GO:0071439 | clathrin complex(GO:0071439) |
| 0.2 | 0.5 | GO:0034272 | phosphatidylinositol 3-kinase complex, class III, type I(GO:0034271) phosphatidylinositol 3-kinase complex, class III, type II(GO:0034272) |
| 0.2 | 1.4 | GO:0044613 | nuclear pore central transport channel(GO:0044613) |
| 0.2 | 1.5 | GO:0031390 | Ctf18 RFC-like complex(GO:0031390) |
| 0.2 | 0.8 | GO:0044316 | cone cell pedicle(GO:0044316) |
| 0.1 | 0.7 | GO:1990130 | Iml1 complex(GO:1990130) |
| 0.1 | 1.2 | GO:1990316 | ATG1/ULK1 kinase complex(GO:1990316) |
| 0.1 | 0.4 | GO:0033648 | host intracellular organelle(GO:0033647) host intracellular membrane-bounded organelle(GO:0033648) |
| 0.1 | 1.3 | GO:0008024 | cyclin/CDK positive transcription elongation factor complex(GO:0008024) |
| 0.1 | 0.6 | GO:0019907 | cyclin-dependent protein kinase activating kinase holoenzyme complex(GO:0019907) |
| 0.1 | 5.4 | GO:0030131 | clathrin adaptor complex(GO:0030131) |
| 0.1 | 1.2 | GO:0005850 | eukaryotic translation initiation factor 2 complex(GO:0005850) |
| 0.1 | 1.6 | GO:0030119 | AP-type membrane coat adaptor complex(GO:0030119) |
| 0.1 | 1.2 | GO:0071141 | SMAD protein complex(GO:0071141) |
| 0.1 | 2.6 | GO:0012507 | ER to Golgi transport vesicle membrane(GO:0012507) |
| 0.1 | 0.5 | GO:0031084 | BLOC-2 complex(GO:0031084) |
| 0.1 | 1.0 | GO:0042587 | glycogen granule(GO:0042587) |
| 0.1 | 0.3 | GO:0005899 | insulin receptor complex(GO:0005899) |
| 0.1 | 0.3 | GO:0035101 | FACT complex(GO:0035101) |
| 0.1 | 1.5 | GO:0030126 | COPI vesicle coat(GO:0030126) |
| 0.1 | 1.3 | GO:0034098 | VCP-NPL4-UFD1 AAA ATPase complex(GO:0034098) |
| 0.1 | 0.5 | GO:0000120 | RNA polymerase I transcription factor complex(GO:0000120) |
| 0.1 | 0.5 | GO:0036396 | MIS complex(GO:0036396) mRNA editing complex(GO:0045293) |
| 0.1 | 0.3 | GO:0033596 | TSC1-TSC2 complex(GO:0033596) |
| 0.1 | 0.5 | GO:0070419 | nonhomologous end joining complex(GO:0070419) |
| 0.1 | 1.4 | GO:0031932 | TORC2 complex(GO:0031932) |
| 0.1 | 1.2 | GO:0017119 | Golgi transport complex(GO:0017119) |
| 0.1 | 0.4 | GO:0060187 | cell pole(GO:0060187) |
| 0.1 | 0.3 | GO:0030905 | retromer, tubulation complex(GO:0030905) |
| 0.1 | 1.9 | GO:0016327 | apicolateral plasma membrane(GO:0016327) |
| 0.1 | 0.7 | GO:0000439 | core TFIIH complex(GO:0000439) |
| 0.1 | 0.3 | GO:1990415 | Pex17p-Pex14p docking complex(GO:1990415) peroxisomal importomer complex(GO:1990429) |
| 0.1 | 1.2 | GO:1902711 | GABA-A receptor complex(GO:1902711) |
| 0.1 | 1.1 | GO:0008385 | IkappaB kinase complex(GO:0008385) |
| 0.1 | 1.7 | GO:0030140 | trans-Golgi network transport vesicle(GO:0030140) |
| 0.1 | 0.5 | GO:0016602 | CCAAT-binding factor complex(GO:0016602) |
| 0.1 | 0.4 | GO:0070876 | SOSS complex(GO:0070876) |
| 0.1 | 0.6 | GO:0070765 | gamma-secretase complex(GO:0070765) |
| 0.1 | 0.4 | GO:0031314 | extrinsic component of mitochondrial inner membrane(GO:0031314) |
| 0.1 | 0.2 | GO:0098592 | cytoplasmic side of apical plasma membrane(GO:0098592) |
| 0.1 | 0.6 | GO:0034750 | Scrib-APC-beta-catenin complex(GO:0034750) |
| 0.1 | 1.0 | GO:0031235 | intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235) |
| 0.1 | 2.1 | GO:0060077 | inhibitory synapse(GO:0060077) |
| 0.1 | 0.3 | GO:0044611 | nuclear pore inner ring(GO:0044611) |
| 0.1 | 0.5 | GO:0005785 | signal recognition particle receptor complex(GO:0005785) |
| 0.1 | 0.5 | GO:0071012 | catalytic step 1 spliceosome(GO:0071012) |
| 0.1 | 0.3 | GO:0001652 | granular component(GO:0001652) |
| 0.1 | 0.5 | GO:0000923 | equatorial microtubule organizing center(GO:0000923) |
| 0.1 | 0.5 | GO:0071818 | BAT3 complex(GO:0071818) ER membrane insertion complex(GO:0072379) |
| 0.1 | 0.3 | GO:0097165 | nuclear stress granule(GO:0097165) |
| 0.1 | 0.3 | GO:0043527 | tRNA methyltransferase complex(GO:0043527) |
| 0.1 | 0.5 | GO:0030132 | clathrin coat of coated pit(GO:0030132) |
| 0.1 | 2.8 | GO:0005788 | endoplasmic reticulum lumen(GO:0005788) |
| 0.1 | 0.8 | GO:0043205 | microfibril(GO:0001527) fibril(GO:0043205) |
| 0.1 | 0.4 | GO:0005828 | kinetochore microtubule(GO:0005828) |
| 0.1 | 0.6 | GO:0030688 | preribosome, small subunit precursor(GO:0030688) |
| 0.1 | 0.2 | GO:0008537 | proteasome activator complex(GO:0008537) |
| 0.1 | 1.0 | GO:0044300 | cerebellar mossy fiber(GO:0044300) |
| 0.1 | 0.8 | GO:0031258 | lamellipodium membrane(GO:0031258) |
| 0.1 | 0.4 | GO:0090543 | Flemming body(GO:0090543) |
| 0.1 | 0.3 | GO:0010369 | chromocenter(GO:0010369) |
| 0.1 | 0.4 | GO:0000137 | Golgi cis cisterna(GO:0000137) |
| 0.1 | 0.2 | GO:0005745 | m-AAA complex(GO:0005745) |
| 0.1 | 0.4 | GO:0097524 | sperm plasma membrane(GO:0097524) |
| 0.0 | 4.5 | GO:0030864 | cortical actin cytoskeleton(GO:0030864) |
| 0.0 | 0.1 | GO:0055087 | Ski complex(GO:0055087) |
| 0.0 | 0.2 | GO:0030314 | junctional membrane complex(GO:0030314) |
| 0.0 | 0.4 | GO:0030991 | intraciliary transport particle A(GO:0030991) |
| 0.0 | 0.2 | GO:0008623 | CHRAC(GO:0008623) |
| 0.0 | 0.8 | GO:0000145 | exocyst(GO:0000145) |
| 0.0 | 2.9 | GO:0031463 | Cul3-RING ubiquitin ligase complex(GO:0031463) |
| 0.0 | 0.2 | GO:0016600 | flotillin complex(GO:0016600) |
| 0.0 | 0.2 | GO:0016222 | procollagen-proline 4-dioxygenase complex(GO:0016222) |
| 0.0 | 0.6 | GO:0005858 | axonemal dynein complex(GO:0005858) |
| 0.0 | 1.0 | GO:0042470 | melanosome(GO:0042470) pigment granule(GO:0048770) |
| 0.0 | 0.5 | GO:0005952 | cAMP-dependent protein kinase complex(GO:0005952) |
| 0.0 | 0.4 | GO:0002177 | manchette(GO:0002177) |
| 0.0 | 0.2 | GO:0000125 | PCAF complex(GO:0000125) |
| 0.0 | 0.4 | GO:0008290 | F-actin capping protein complex(GO:0008290) |
| 0.0 | 0.9 | GO:0005680 | anaphase-promoting complex(GO:0005680) |
| 0.0 | 0.9 | GO:0034451 | centriolar satellite(GO:0034451) |
| 0.0 | 0.0 | GO:0000931 | gamma-tubulin large complex(GO:0000931) gamma-tubulin ring complex(GO:0008274) |
| 0.0 | 0.7 | GO:0035327 | transcriptionally active chromatin(GO:0035327) |
| 0.0 | 0.1 | GO:0032541 | cortical endoplasmic reticulum(GO:0032541) |
| 0.0 | 0.3 | GO:0032045 | guanyl-nucleotide exchange factor complex(GO:0032045) |
| 0.0 | 0.6 | GO:0005671 | Ada2/Gcn5/Ada3 transcription activator complex(GO:0005671) |
| 0.0 | 0.4 | GO:0035068 | micro-ribonucleoprotein complex(GO:0035068) |
| 0.0 | 0.3 | GO:1990909 | Wnt signalosome(GO:1990909) |
| 0.0 | 0.2 | GO:0098536 | deuterosome(GO:0098536) |
| 0.0 | 0.1 | GO:0045160 | myosin I complex(GO:0045160) |
| 0.0 | 0.3 | GO:0035859 | Seh1-associated complex(GO:0035859) |
| 0.0 | 0.3 | GO:0034518 | mRNA cap binding complex(GO:0005845) RNA cap binding complex(GO:0034518) |
| 0.0 | 0.3 | GO:0089701 | U2AF(GO:0089701) |
| 0.0 | 0.1 | GO:0071797 | LUBAC complex(GO:0071797) |
| 0.0 | 0.2 | GO:0000408 | EKC/KEOPS complex(GO:0000408) |
| 0.0 | 0.1 | GO:0035061 | interchromatin granule(GO:0035061) |
| 0.0 | 0.1 | GO:0020018 | ciliary pocket(GO:0020016) ciliary pocket membrane(GO:0020018) |
| 0.0 | 1.2 | GO:1990391 | DNA repair complex(GO:1990391) |
| 0.0 | 0.1 | GO:0030690 | Noc complex(GO:0030689) Noc1p-Noc2p complex(GO:0030690) |
| 0.0 | 0.2 | GO:0042588 | zymogen granule(GO:0042588) |
| 0.0 | 0.2 | GO:0072357 | PTW/PP1 phosphatase complex(GO:0072357) |
| 0.0 | 0.1 | GO:1990111 | spermatoproteasome complex(GO:1990111) |
| 0.0 | 0.1 | GO:0000421 | autophagosome membrane(GO:0000421) |
| 0.0 | 0.1 | GO:0033276 | transcription factor TFTC complex(GO:0033276) |
| 0.0 | 0.1 | GO:0034673 | inhibin-betaglycan-ActRII complex(GO:0034673) |
| 0.0 | 0.3 | GO:0042555 | MCM complex(GO:0042555) |
| 0.0 | 0.8 | GO:0030863 | cortical cytoskeleton(GO:0030863) |
| 0.0 | 0.5 | GO:0035253 | ciliary rootlet(GO:0035253) |
| 0.0 | 0.1 | GO:0097441 | basilar dendrite(GO:0097441) |
| 0.0 | 0.1 | GO:0034388 | Pwp2p-containing subcomplex of 90S preribosome(GO:0034388) |
| 0.0 | 0.1 | GO:0044352 | pinosome(GO:0044352) macropinosome(GO:0044354) |
| 0.0 | 0.2 | GO:0031464 | Cul4A-RING E3 ubiquitin ligase complex(GO:0031464) |
| 0.0 | 0.4 | GO:0035102 | PRC1 complex(GO:0035102) |
| 0.0 | 0.2 | GO:0016010 | dystrophin-associated glycoprotein complex(GO:0016010) glycoprotein complex(GO:0090665) |
| 0.0 | 0.1 | GO:0070826 | paraferritin complex(GO:0070826) |
| 0.0 | 0.1 | GO:0000220 | vacuolar proton-transporting V-type ATPase, V0 domain(GO:0000220) |
| 0.0 | 0.6 | GO:0071339 | MLL1/2 complex(GO:0044665) MLL1 complex(GO:0071339) |
| 0.0 | 0.6 | GO:0031307 | integral component of mitochondrial outer membrane(GO:0031307) |
| 0.0 | 0.3 | GO:0036513 | Derlin-1 retrotranslocation complex(GO:0036513) |
| 0.0 | 0.1 | GO:0030870 | Mre11 complex(GO:0030870) |
| 0.0 | 0.9 | GO:0043034 | costamere(GO:0043034) |
| 0.0 | 0.7 | GO:0005868 | cytoplasmic dynein complex(GO:0005868) |
| 0.0 | 0.6 | GO:0030686 | 90S preribosome(GO:0030686) |
| 0.0 | 0.2 | GO:0097136 | Bcl-2 family protein complex(GO:0097136) |
| 0.0 | 0.1 | GO:0044614 | nuclear pore cytoplasmic filaments(GO:0044614) |
| 0.0 | 0.3 | GO:0033017 | sarcoplasmic reticulum membrane(GO:0033017) |
| 0.0 | 0.7 | GO:0005637 | nuclear inner membrane(GO:0005637) |
| 0.0 | 1.3 | GO:0005811 | lipid particle(GO:0005811) |
| 0.0 | 0.2 | GO:0005787 | signal peptidase complex(GO:0005787) |
| 0.0 | 0.7 | GO:0016529 | sarcoplasmic reticulum(GO:0016529) |
| 0.0 | 0.2 | GO:0030914 | STAGA complex(GO:0030914) |
| 0.0 | 0.2 | GO:0030008 | TRAPP complex(GO:0030008) |
| 0.0 | 0.4 | GO:0030014 | CCR4-NOT complex(GO:0030014) |
| 0.0 | 1.3 | GO:0010494 | cytoplasmic stress granule(GO:0010494) |
| 0.0 | 0.3 | GO:0043196 | varicosity(GO:0043196) |
| 0.0 | 0.1 | GO:0017059 | serine C-palmitoyltransferase complex(GO:0017059) endoplasmic reticulum palmitoyltransferase complex(GO:0031211) |
| 0.0 | 0.3 | GO:0030687 | preribosome, large subunit precursor(GO:0030687) |
| 0.0 | 0.1 | GO:0031080 | nuclear pore outer ring(GO:0031080) |
| 0.0 | 0.5 | GO:0005790 | smooth endoplasmic reticulum(GO:0005790) |
| 0.0 | 0.6 | GO:0015030 | Cajal body(GO:0015030) |
| 0.0 | 0.1 | GO:0016281 | eukaryotic translation initiation factor 4F complex(GO:0016281) |
| 0.0 | 0.2 | GO:0005892 | acetylcholine-gated channel complex(GO:0005892) |
| 0.0 | 0.1 | GO:0098837 | postsynaptic recycling endosome(GO:0098837) |
| 0.0 | 0.1 | GO:0060053 | neurofilament cytoskeleton(GO:0060053) |
| 0.0 | 0.1 | GO:0000127 | transcription factor TFIIIC complex(GO:0000127) |
| 0.0 | 0.1 | GO:0033503 | HULC complex(GO:0033503) |
| 0.0 | 0.1 | GO:0030877 | beta-catenin destruction complex(GO:0030877) |
| 0.0 | 0.1 | GO:0032591 | dendritic spine membrane(GO:0032591) |
| 0.0 | 0.1 | GO:0061617 | MICOS complex(GO:0061617) |
| 0.0 | 0.1 | GO:0000347 | THO complex(GO:0000347) THO complex part of transcription export complex(GO:0000445) |
| 0.0 | 0.4 | GO:0031901 | early endosome membrane(GO:0031901) |
| 0.0 | 0.1 | GO:0045334 | clathrin-coated endocytic vesicle(GO:0045334) |
| 0.0 | 0.1 | GO:0042382 | paraspeckles(GO:0042382) |
| 0.0 | 0.2 | GO:0030904 | retromer complex(GO:0030904) |
| 0.0 | 0.1 | GO:0031313 | extrinsic component of endosome membrane(GO:0031313) |
| 0.0 | 0.1 | GO:0030896 | checkpoint clamp complex(GO:0030896) |
| 0.0 | 0.0 | GO:0097433 | dense body(GO:0097433) |
| 0.0 | 2.0 | GO:0031965 | nuclear membrane(GO:0031965) |
| 0.0 | 2.2 | GO:0005802 | trans-Golgi network(GO:0005802) |
| 0.0 | 0.2 | GO:0070971 | endoplasmic reticulum exit site(GO:0070971) |
| 0.0 | 0.6 | GO:0005793 | endoplasmic reticulum-Golgi intermediate compartment(GO:0005793) |
| 0.0 | 2.5 | GO:0016324 | apical plasma membrane(GO:0016324) |
| 0.0 | 0.3 | GO:0005721 | pericentric heterochromatin(GO:0005721) |
| 0.0 | 0.6 | GO:0042645 | nucleoid(GO:0009295) mitochondrial nucleoid(GO:0042645) |
| 0.0 | 0.0 | GO:0001405 | presequence translocase-associated import motor(GO:0001405) |
| 0.0 | 0.4 | GO:0005891 | voltage-gated calcium channel complex(GO:0005891) |
| 0.0 | 0.1 | GO:0005964 | phosphorylase kinase complex(GO:0005964) |
| 0.0 | 0.9 | GO:0016605 | PML body(GO:0016605) |
| 0.0 | 0.1 | GO:0005658 | alpha DNA polymerase:primase complex(GO:0005658) |
Gene overrepresentation in molecular_function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.6 | 1.8 | GO:0043682 | copper-exporting ATPase activity(GO:0004008) copper-transporting ATPase activity(GO:0043682) |
| 0.4 | 1.8 | GO:0015410 | manganese-transporting ATPase activity(GO:0015410) |
| 0.4 | 1.2 | GO:0035500 | MH2 domain binding(GO:0035500) |
| 0.4 | 2.0 | GO:0086080 | protein binding involved in heterotypic cell-cell adhesion(GO:0086080) |
| 0.4 | 1.1 | GO:0004677 | DNA-dependent protein kinase activity(GO:0004677) |
| 0.4 | 2.3 | GO:0003910 | DNA ligase activity(GO:0003909) DNA ligase (ATP) activity(GO:0003910) |
| 0.4 | 1.1 | GO:0016979 | lipoate-protein ligase activity(GO:0016979) |
| 0.4 | 1.5 | GO:0035473 | lipase binding(GO:0035473) |
| 0.4 | 1.1 | GO:0001129 | RNA polymerase II transcription factor activity, TBP-class protein binding, involved in preinitiation complex assembly(GO:0001129) RNA polymerase II transcription factor activity, TBP-class protein binding(GO:0001132) |
| 0.3 | 1.0 | GO:1990450 | linear polyubiquitin binding(GO:1990450) |
| 0.3 | 1.0 | GO:0033699 | DNA 5'-adenosine monophosphate hydrolase activity(GO:0033699) |
| 0.3 | 1.0 | GO:0001042 | RNA polymerase I core binding(GO:0001042) |
| 0.3 | 1.3 | GO:0043515 | kinetochore binding(GO:0043515) |
| 0.3 | 1.0 | GO:0034647 | histone demethylase activity (H3-trimethyl-K4 specific)(GO:0034647) |
| 0.3 | 1.3 | GO:0004105 | choline-phosphate cytidylyltransferase activity(GO:0004105) |
| 0.3 | 1.3 | GO:0005166 | neurotrophin p75 receptor binding(GO:0005166) |
| 0.2 | 0.7 | GO:0098973 | structural constituent of synapse(GO:0098918) structural constituent of postsynaptic actin cytoskeleton(GO:0098973) |
| 0.2 | 0.7 | GO:0001156 | TFIIIC-class transcription factor binding(GO:0001156) |
| 0.2 | 1.2 | GO:1904315 | GABA-gated chloride ion channel activity(GO:0022851) transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1904315) |
| 0.2 | 3.9 | GO:0070300 | phosphatidic acid binding(GO:0070300) |
| 0.2 | 0.8 | GO:0005222 | intracellular cAMP activated cation channel activity(GO:0005222) |
| 0.2 | 1.5 | GO:0008318 | protein prenyltransferase activity(GO:0008318) |
| 0.2 | 3.4 | GO:0008179 | adenylate cyclase binding(GO:0008179) |
| 0.2 | 0.9 | GO:0004839 | ubiquitin activating enzyme activity(GO:0004839) |
| 0.2 | 0.7 | GO:0034511 | U3 snoRNA binding(GO:0034511) |
| 0.2 | 0.5 | GO:0035575 | histone demethylase activity (H4-K20 specific)(GO:0035575) |
| 0.2 | 1.5 | GO:0035251 | UDP-glucosyltransferase activity(GO:0035251) |
| 0.2 | 0.6 | GO:0004515 | nicotinamide-nucleotide adenylyltransferase activity(GO:0000309) nicotinate-nucleotide adenylyltransferase activity(GO:0004515) |
| 0.2 | 0.8 | GO:0050265 | RNA uridylyltransferase activity(GO:0050265) |
| 0.2 | 0.9 | GO:0045545 | syndecan binding(GO:0045545) |
| 0.1 | 0.4 | GO:0001032 | RNA polymerase III type 3 promoter DNA binding(GO:0001032) |
| 0.1 | 1.1 | GO:0031811 | G-protein coupled nucleotide receptor binding(GO:0031811) P2Y1 nucleotide receptor binding(GO:0031812) |
| 0.1 | 1.1 | GO:0001135 | transcription factor activity, RNA polymerase II transcription factor recruiting(GO:0001135) |
| 0.1 | 1.9 | GO:0034450 | ubiquitin-ubiquitin ligase activity(GO:0034450) |
| 0.1 | 0.7 | GO:0004792 | thiosulfate sulfurtransferase activity(GO:0004792) |
| 0.1 | 1.5 | GO:0003689 | DNA clamp loader activity(GO:0003689) protein-DNA loading ATPase activity(GO:0033170) |
| 0.1 | 0.5 | GO:0000179 | rRNA (adenine-N6,N6-)-dimethyltransferase activity(GO:0000179) |
| 0.1 | 0.9 | GO:0071253 | connexin binding(GO:0071253) |
| 0.1 | 2.9 | GO:0017056 | structural constituent of nuclear pore(GO:0017056) |
| 0.1 | 0.4 | GO:0031871 | proteinase activated receptor binding(GO:0031871) |
| 0.1 | 0.5 | GO:0016422 | mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity(GO:0016422) |
| 0.1 | 0.1 | GO:0009383 | rRNA (cytosine-C5-)-methyltransferase activity(GO:0009383) |
| 0.1 | 0.4 | GO:0008109 | N-acetyllactosaminide beta-1,6-N-acetylglucosaminyltransferase activity(GO:0008109) |
| 0.1 | 0.6 | GO:0043812 | phosphatidylinositol-4-phosphate phosphatase activity(GO:0043812) |
| 0.1 | 0.6 | GO:0003917 | DNA topoisomerase type I activity(GO:0003917) |
| 0.1 | 1.0 | GO:0016428 | tRNA (cytosine-5-)-methyltransferase activity(GO:0016428) |
| 0.1 | 0.5 | GO:0004359 | glutaminase activity(GO:0004359) |
| 0.1 | 0.3 | GO:0001056 | RNA polymerase III activity(GO:0001056) |
| 0.1 | 0.4 | GO:0033883 | pyridoxal phosphatase activity(GO:0033883) |
| 0.1 | 0.1 | GO:0001179 | RNA polymerase I transcription factor binding(GO:0001179) |
| 0.1 | 0.8 | GO:0042500 | aspartic endopeptidase activity, intramembrane cleaving(GO:0042500) |
| 0.1 | 0.3 | GO:0004489 | methylenetetrahydrofolate reductase (NAD(P)H) activity(GO:0004489) |
| 0.1 | 0.3 | GO:0017099 | very-long-chain-acyl-CoA dehydrogenase activity(GO:0017099) |
| 0.1 | 0.6 | GO:0070728 | leucine binding(GO:0070728) |
| 0.1 | 2.2 | GO:0046961 | proton-transporting ATPase activity, rotational mechanism(GO:0046961) |
| 0.1 | 0.5 | GO:0033188 | sphingomyelin synthase activity(GO:0033188) ceramide cholinephosphotransferase activity(GO:0047493) |
| 0.1 | 4.6 | GO:0070063 | RNA polymerase binding(GO:0070063) |
| 0.1 | 0.4 | GO:0036033 | mediator complex binding(GO:0036033) |
| 0.1 | 2.3 | GO:0008139 | nuclear localization sequence binding(GO:0008139) |
| 0.1 | 1.3 | GO:0035612 | AP-2 adaptor complex binding(GO:0035612) |
| 0.1 | 0.3 | GO:0004568 | chitinase activity(GO:0004568) |
| 0.1 | 1.1 | GO:0070008 | serine-type exopeptidase activity(GO:0070008) |
| 0.1 | 1.6 | GO:0050321 | tau-protein kinase activity(GO:0050321) |
| 0.1 | 0.9 | GO:0008190 | eukaryotic initiation factor 4E binding(GO:0008190) |
| 0.1 | 0.5 | GO:0035312 | 5'-3' exodeoxyribonuclease activity(GO:0035312) |
| 0.1 | 0.3 | GO:0070139 | ubiquitin-like protein-specific endopeptidase activity(GO:0070137) SUMO-specific endopeptidase activity(GO:0070139) |
| 0.1 | 0.7 | GO:0003747 | translation release factor activity(GO:0003747) translation termination factor activity(GO:0008079) |
| 0.1 | 0.9 | GO:0031802 | type 5 metabotropic glutamate receptor binding(GO:0031802) |
| 0.1 | 1.6 | GO:0008353 | RNA polymerase II carboxy-terminal domain kinase activity(GO:0008353) |
| 0.1 | 0.2 | GO:0001160 | transcription termination site sequence-specific DNA binding(GO:0001147) transcription termination site DNA binding(GO:0001160) |
| 0.1 | 0.2 | GO:0080084 | RNA polymerase III type 1 promoter DNA binding(GO:0001030) RNA polymerase III type 2 promoter DNA binding(GO:0001031) 5S rDNA binding(GO:0080084) |
| 0.1 | 0.2 | GO:0016501 | prostacyclin receptor activity(GO:0016501) |
| 0.1 | 0.7 | GO:0019003 | GDP binding(GO:0019003) |
| 0.1 | 0.6 | GO:0003886 | DNA (cytosine-5-)-methyltransferase activity(GO:0003886) |
| 0.1 | 0.3 | GO:0003827 | alpha-1,3-mannosylglycoprotein 2-beta-N-acetylglucosaminyltransferase activity(GO:0003827) |
| 0.1 | 0.2 | GO:0071207 | histone pre-mRNA stem-loop binding(GO:0071207) |
| 0.1 | 0.3 | GO:0008240 | tripeptidyl-peptidase activity(GO:0008240) |
| 0.1 | 0.5 | GO:0099609 | microtubule lateral binding(GO:0099609) |
| 0.1 | 0.3 | GO:1990460 | leptin receptor binding(GO:1990460) |
| 0.1 | 0.2 | GO:0000386 | second spliceosomal transesterification activity(GO:0000386) |
| 0.1 | 0.4 | GO:0004468 | lysine N-acetyltransferase activity, acting on acetyl phosphate as donor(GO:0004468) |
| 0.1 | 0.5 | GO:0052629 | phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity(GO:0052629) |
| 0.1 | 3.1 | GO:0051018 | protein kinase A binding(GO:0051018) |
| 0.1 | 0.6 | GO:0004445 | inositol-polyphosphate 5-phosphatase activity(GO:0004445) inositol trisphosphate phosphatase activity(GO:0046030) |
| 0.1 | 0.3 | GO:0080019 | fatty-acyl-CoA reductase (alcohol-forming) activity(GO:0080019) |
| 0.1 | 1.2 | GO:0003950 | NAD+ ADP-ribosyltransferase activity(GO:0003950) |
| 0.1 | 0.2 | GO:1990955 | G-rich single-stranded DNA binding(GO:1990955) |
| 0.1 | 0.4 | GO:0002135 | CTP binding(GO:0002135) |
| 0.1 | 0.8 | GO:0004596 | peptide alpha-N-acetyltransferase activity(GO:0004596) |
| 0.1 | 0.2 | GO:0004830 | tryptophan-tRNA ligase activity(GO:0004830) |
| 0.1 | 0.3 | GO:0051880 | G-quadruplex DNA binding(GO:0051880) |
| 0.1 | 0.1 | GO:0004637 | phosphoribosylamine-glycine ligase activity(GO:0004637) |
| 0.1 | 0.5 | GO:0031543 | peptidyl-proline dioxygenase activity(GO:0031543) |
| 0.1 | 3.7 | GO:0030276 | clathrin binding(GO:0030276) |
| 0.1 | 0.2 | GO:0097003 | adipokinetic hormone receptor activity(GO:0097003) |
| 0.1 | 0.2 | GO:0047179 | platelet-activating factor acetyltransferase activity(GO:0047179) |
| 0.1 | 0.4 | GO:1990380 | Lys48-specific deubiquitinase activity(GO:1990380) |
| 0.1 | 0.3 | GO:0000990 | transcription factor activity, core RNA polymerase binding(GO:0000990) |
| 0.1 | 2.1 | GO:0004177 | aminopeptidase activity(GO:0004177) |
| 0.1 | 0.4 | GO:0005138 | interleukin-6 receptor binding(GO:0005138) |
| 0.1 | 0.3 | GO:0019961 | interferon binding(GO:0019961) |
| 0.0 | 0.2 | GO:0004176 | ATP-dependent peptidase activity(GO:0004176) |
| 0.0 | 0.3 | GO:0097371 | MDM2/MDM4 family protein binding(GO:0097371) |
| 0.0 | 0.2 | GO:0031493 | nucleosomal histone binding(GO:0031493) |
| 0.0 | 0.4 | GO:0019869 | chloride channel inhibitor activity(GO:0019869) |
| 0.0 | 2.0 | GO:0031624 | ubiquitin conjugating enzyme binding(GO:0031624) |
| 0.0 | 0.2 | GO:0051377 | mannose-ethanolamine phosphotransferase activity(GO:0051377) |
| 0.0 | 0.5 | GO:0051011 | microtubule minus-end binding(GO:0051011) |
| 0.0 | 1.3 | GO:0030742 | GTP-dependent protein binding(GO:0030742) |
| 0.0 | 0.4 | GO:0003993 | acid phosphatase activity(GO:0003993) |
| 0.0 | 0.2 | GO:0002151 | G-quadruplex RNA binding(GO:0002151) |
| 0.0 | 0.5 | GO:0005068 | transmembrane receptor protein tyrosine kinase adaptor activity(GO:0005068) |
| 0.0 | 4.9 | GO:0000149 | SNARE binding(GO:0000149) |
| 0.0 | 0.4 | GO:0004571 | mannosyl-oligosaccharide 1,2-alpha-mannosidase activity(GO:0004571) |
| 0.0 | 0.2 | GO:0042134 | rRNA primary transcript binding(GO:0042134) |
| 0.0 | 0.1 | GO:0044715 | 8-oxo-dGDP phosphatase activity(GO:0044715) |
| 0.0 | 0.1 | GO:0032139 | dinucleotide insertion or deletion binding(GO:0032139) single guanine insertion binding(GO:0032142) |
| 0.0 | 0.7 | GO:0000146 | microfilament motor activity(GO:0000146) |
| 0.0 | 0.4 | GO:0050815 | phosphoserine binding(GO:0050815) |
| 0.0 | 0.5 | GO:0005545 | 1-phosphatidylinositol binding(GO:0005545) |
| 0.0 | 1.0 | GO:0045503 | dynein light chain binding(GO:0045503) |
| 0.0 | 0.1 | GO:0001888 | glucuronyl-galactosyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity(GO:0001888) |
| 0.0 | 0.2 | GO:0004652 | polynucleotide adenylyltransferase activity(GO:0004652) |
| 0.0 | 0.2 | GO:0008607 | cAMP-dependent protein kinase regulator activity(GO:0008603) phosphorylase kinase regulator activity(GO:0008607) |
| 0.0 | 0.6 | GO:0051010 | microtubule plus-end binding(GO:0051010) |
| 0.0 | 0.4 | GO:0097027 | ubiquitin-protein transferase activator activity(GO:0097027) |
| 0.0 | 0.1 | GO:0004758 | serine C-palmitoyltransferase activity(GO:0004758) C-palmitoyltransferase activity(GO:0016454) |
| 0.0 | 0.1 | GO:0004069 | L-aspartate:2-oxoglutarate aminotransferase activity(GO:0004069) |
| 0.0 | 0.1 | GO:0015254 | glycerol channel activity(GO:0015254) |
| 0.0 | 0.2 | GO:0005047 | signal recognition particle binding(GO:0005047) |
| 0.0 | 0.9 | GO:0005385 | zinc ion transmembrane transporter activity(GO:0005385) |
| 0.0 | 0.2 | GO:0000340 | RNA 7-methylguanosine cap binding(GO:0000340) |
| 0.0 | 0.1 | GO:0004694 | eukaryotic translation initiation factor 2alpha kinase activity(GO:0004694) |
| 0.0 | 0.2 | GO:0071532 | ankyrin repeat binding(GO:0071532) |
| 0.0 | 0.1 | GO:0004348 | glucosylceramidase activity(GO:0004348) |
| 0.0 | 1.1 | GO:0043027 | cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027) |
| 0.0 | 0.3 | GO:0043023 | ribosomal large subunit binding(GO:0043023) |
| 0.0 | 0.2 | GO:0090599 | alpha-glucosidase activity(GO:0090599) |
| 0.0 | 0.5 | GO:0017160 | Ral GTPase binding(GO:0017160) |
| 0.0 | 0.4 | GO:0008517 | folic acid transporter activity(GO:0008517) |
| 0.0 | 0.4 | GO:0035004 | 1-phosphatidylinositol-3-kinase activity(GO:0016303) phosphatidylinositol 3-kinase activity(GO:0035004) |
| 0.0 | 0.2 | GO:0005519 | cytoskeletal regulatory protein binding(GO:0005519) |
| 0.0 | 0.2 | GO:0047631 | ADP-ribose diphosphatase activity(GO:0047631) |
| 0.0 | 0.2 | GO:0051434 | BH3 domain binding(GO:0051434) |
| 0.0 | 0.1 | GO:0070012 | oligopeptidase activity(GO:0070012) |
| 0.0 | 0.3 | GO:0015643 | toxic substance binding(GO:0015643) |
| 0.0 | 0.9 | GO:0008536 | Ran GTPase binding(GO:0008536) |
| 0.0 | 0.0 | GO:0004180 | carboxypeptidase activity(GO:0004180) |
| 0.0 | 0.2 | GO:0031821 | G-protein coupled serotonin receptor binding(GO:0031821) |
| 0.0 | 0.1 | GO:0030621 | U4 snRNA binding(GO:0030621) |
| 0.0 | 0.5 | GO:0004535 | poly(A)-specific ribonuclease activity(GO:0004535) |
| 0.0 | 1.2 | GO:0036002 | pre-mRNA binding(GO:0036002) |
| 0.0 | 0.3 | GO:0005078 | MAP-kinase scaffold activity(GO:0005078) |
| 0.0 | 0.1 | GO:0046899 | nucleoside triphosphate adenylate kinase activity(GO:0046899) |
| 0.0 | 0.3 | GO:0016805 | dipeptidase activity(GO:0016805) |
| 0.0 | 1.2 | GO:0016876 | aminoacyl-tRNA ligase activity(GO:0004812) ligase activity, forming carbon-oxygen bonds(GO:0016875) ligase activity, forming aminoacyl-tRNA and related compounds(GO:0016876) |
| 0.0 | 0.1 | GO:0004499 | N,N-dimethylaniline monooxygenase activity(GO:0004499) |
| 0.0 | 0.1 | GO:0004345 | glucose-6-phosphate dehydrogenase activity(GO:0004345) |
| 0.0 | 0.1 | GO:0034452 | dynactin binding(GO:0034452) |
| 0.0 | 0.2 | GO:0003964 | telomerase activity(GO:0003720) RNA-directed DNA polymerase activity(GO:0003964) |
| 0.0 | 0.4 | GO:0016709 | oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen(GO:0016709) |
| 0.0 | 0.4 | GO:0050692 | DBD domain binding(GO:0050692) |
| 0.0 | 0.1 | GO:0052742 | phosphatidylinositol kinase activity(GO:0052742) |
| 0.0 | 0.1 | GO:0015086 | cadmium ion transmembrane transporter activity(GO:0015086) lead ion transmembrane transporter activity(GO:0015094) vanadium ion transmembrane transporter activity(GO:0015100) ferrous iron uptake transmembrane transporter activity(GO:0015639) |
| 0.0 | 0.1 | GO:0005375 | copper ion transmembrane transporter activity(GO:0005375) |
| 0.0 | 0.1 | GO:0016206 | catechol O-methyltransferase activity(GO:0016206) |
| 0.0 | 0.9 | GO:0051019 | mitogen-activated protein kinase binding(GO:0051019) |
| 0.0 | 0.3 | GO:1904264 | ubiquitin protein ligase activity involved in ERAD pathway(GO:1904264) |
| 0.0 | 0.4 | GO:0001191 | transcriptional repressor activity, RNA polymerase II transcription factor binding(GO:0001191) |
| 0.0 | 0.2 | GO:0015386 | potassium:proton antiporter activity(GO:0015386) |
| 0.0 | 0.1 | GO:0000822 | inositol hexakisphosphate binding(GO:0000822) |
| 0.0 | 0.1 | GO:0050544 | arachidonic acid binding(GO:0050544) |
| 0.0 | 1.5 | GO:0000977 | RNA polymerase II regulatory region sequence-specific DNA binding(GO:0000977) |
| 0.0 | 0.9 | GO:0001784 | phosphotyrosine binding(GO:0001784) |
| 0.0 | 0.3 | GO:0004653 | polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653) |
| 0.0 | 0.0 | GO:0051575 | 5'-deoxyribose-5-phosphate lyase activity(GO:0051575) |
| 0.0 | 0.1 | GO:0008802 | betaine-aldehyde dehydrogenase activity(GO:0008802) |
| 0.0 | 0.1 | GO:0008494 | translation activator activity(GO:0008494) |
| 0.0 | 0.3 | GO:0005247 | voltage-gated chloride channel activity(GO:0005247) |
| 0.0 | 0.1 | GO:0008310 | single-stranded DNA 3'-5' exodeoxyribonuclease activity(GO:0008310) |
| 0.0 | 0.7 | GO:0004222 | metalloendopeptidase activity(GO:0004222) |
| 0.0 | 0.3 | GO:0031489 | myosin V binding(GO:0031489) |
| 0.0 | 0.5 | GO:0016278 | lysine N-methyltransferase activity(GO:0016278) protein-lysine N-methyltransferase activity(GO:0016279) |
| 0.0 | 0.2 | GO:0070566 | adenylyltransferase activity(GO:0070566) |
| 0.0 | 0.4 | GO:0004709 | MAP kinase kinase kinase activity(GO:0004709) |
| 0.0 | 0.3 | GO:0042975 | peroxisome proliferator activated receptor binding(GO:0042975) |
| 0.0 | 1.1 | GO:0051219 | phosphoprotein binding(GO:0051219) |
| 0.0 | 0.1 | GO:0070290 | N-acylphosphatidylethanolamine-specific phospholipase D activity(GO:0070290) |
| 0.0 | 1.2 | GO:0033613 | activating transcription factor binding(GO:0033613) |
| 0.0 | 0.1 | GO:0004691 | cAMP-dependent protein kinase activity(GO:0004691) |
| 0.0 | 0.1 | GO:0017002 | activin-activated receptor activity(GO:0017002) |
| 0.0 | 1.5 | GO:0008013 | beta-catenin binding(GO:0008013) |
| 0.0 | 0.0 | GO:0070579 | methylcytosine dioxygenase activity(GO:0070579) |
| 0.0 | 1.6 | GO:0001104 | RNA polymerase II transcription cofactor activity(GO:0001104) |
| 0.0 | 0.3 | GO:0050681 | androgen receptor binding(GO:0050681) |
| 0.0 | 0.9 | GO:0005179 | hormone activity(GO:0005179) |
| 0.0 | 0.1 | GO:0019788 | NEDD8 transferase activity(GO:0019788) |
| 0.0 | 1.4 | GO:0004860 | protein kinase inhibitor activity(GO:0004860) |
| 0.0 | 0.2 | GO:0004869 | cysteine-type endopeptidase inhibitor activity(GO:0004869) |
| 0.0 | 0.8 | GO:0004725 | protein tyrosine phosphatase activity(GO:0004725) |
| 0.0 | 0.4 | GO:0071889 | 14-3-3 protein binding(GO:0071889) |
| 0.0 | 0.1 | GO:0003880 | protein C-terminal carboxyl O-methyltransferase activity(GO:0003880) |
| 0.0 | 0.3 | GO:0001221 | transcription cofactor binding(GO:0001221) |
| 0.0 | 0.0 | GO:0001134 | transcription factor activity, transcription factor recruiting(GO:0001134) |
| 0.0 | 0.6 | GO:0008138 | protein tyrosine/serine/threonine phosphatase activity(GO:0008138) |
| 0.0 | 0.4 | GO:0004407 | histone deacetylase activity(GO:0004407) protein deacetylase activity(GO:0033558) |
| 0.0 | 0.1 | GO:0016004 | phospholipase activator activity(GO:0016004) lipase activator activity(GO:0060229) |
| 0.0 | 0.2 | GO:0008143 | poly(A) binding(GO:0008143) |
| 0.0 | 0.1 | GO:0008417 | fucosyltransferase activity(GO:0008417) |
| 0.0 | 0.1 | GO:0004689 | phosphorylase kinase activity(GO:0004689) |
| 0.0 | 0.0 | GO:0061628 | H3K27me3 modified histone binding(GO:0061628) |
| 0.0 | 0.2 | GO:0017049 | GTP-Rho binding(GO:0017049) |
| 0.0 | 0.4 | GO:0004115 | 3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115) |
| 0.0 | 0.2 | GO:0008484 | sulfuric ester hydrolase activity(GO:0008484) |
| 0.0 | 0.2 | GO:0005158 | insulin receptor binding(GO:0005158) |
| 0.0 | 0.2 | GO:0035497 | cAMP response element binding(GO:0035497) |
| 0.0 | 0.0 | GO:0005093 | Rab GDP-dissociation inhibitor activity(GO:0005093) |
| 0.0 | 7.4 | GO:0008270 | zinc ion binding(GO:0008270) |
| 0.0 | 0.1 | GO:0043028 | cysteine-type endopeptidase regulator activity involved in apoptotic process(GO:0043028) |
| 0.0 | 0.2 | GO:0019789 | SUMO transferase activity(GO:0019789) |
| 0.0 | 0.3 | GO:0070273 | phosphatidylinositol-4-phosphate binding(GO:0070273) |
| 0.0 | 0.0 | GO:0031687 | A2A adenosine receptor binding(GO:0031687) |
| 0.0 | 0.1 | GO:0000014 | single-stranded DNA endodeoxyribonuclease activity(GO:0000014) |
| 0.0 | 10.8 | GO:0003700 | nucleic acid binding transcription factor activity(GO:0001071) transcription factor activity, sequence-specific DNA binding(GO:0003700) |
| 0.0 | 0.2 | GO:0003841 | 1-acylglycerol-3-phosphate O-acyltransferase activity(GO:0003841) |
| 0.0 | 0.3 | GO:0030515 | snoRNA binding(GO:0030515) |
| 0.0 | 0.2 | GO:0042974 | retinoic acid receptor binding(GO:0042974) |
| 0.0 | 0.1 | GO:0015197 | peptide transporter activity(GO:0015197) |
| 0.0 | 0.0 | GO:0000033 | alpha-1,3-mannosyltransferase activity(GO:0000033) |
| 0.0 | 0.0 | GO:0000339 | RNA cap binding(GO:0000339) |
Gene overrepresentation in C2:CP category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 1.0 | SA_G2_AND_M_PHASES | Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition. |
| 0.1 | 2.6 | PID_DNA_PK_PATHWAY | DNA-PK pathway in nonhomologous end joining |
| 0.1 | 2.6 | PID_WNT_CANONICAL_PATHWAY | Canonical Wnt signaling pathway |
| 0.1 | 0.3 | SA_G1_AND_S_PHASES | Cdk2, 4, and 6 bind cyclin D in G1, while cdk2/cyclin E promotes the G1/S transition. |
| 0.1 | 1.6 | SA_CASPASE_CASCADE | Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade. |
| 0.1 | 2.0 | PID_NFKAPPAB_CANONICAL_PATHWAY | Canonical NF-kappaB pathway |
| 0.1 | 0.6 | PID_TCR_JNK_PATHWAY | JNK signaling in the CD4+ TCR pathway |
| 0.0 | 1.4 | PID_PI3KCI_AKT_PATHWAY | Class I PI3K signaling events mediated by Akt |
| 0.0 | 1.3 | ST_GA12_PATHWAY | G alpha 12 Pathway |
| 0.0 | 4.1 | SIG_INSULIN_RECEPTOR_PATHWAY_IN_CARDIAC_MYOCYTES | Genes related to the insulin receptor pathway |
| 0.0 | 1.1 | PID_ARF_3PATHWAY | Arf1 pathway |
| 0.0 | 0.6 | PID_CIRCADIAN_PATHWAY | Circadian rhythm pathway |
| 0.0 | 0.6 | PID_SYNDECAN_3_PATHWAY | Syndecan-3-mediated signaling events |
| 0.0 | 1.3 | PID_TNF_PATHWAY | TNF receptor signaling pathway |
| 0.0 | 0.6 | PID_SYNDECAN_2_PATHWAY | Syndecan-2-mediated signaling events |
| 0.0 | 0.7 | SIG_PIP3_SIGNALING_IN_CARDIAC_MYOCTES | Genes related to PIP3 signaling in cardiac myocytes |
| 0.0 | 1.0 | PID_INSULIN_PATHWAY | Insulin Pathway |
| 0.0 | 0.5 | PID_RET_PATHWAY | Signaling events regulated by Ret tyrosine kinase |
| 0.0 | 0.1 | PID_IL8_CXCR2_PATHWAY | IL8- and CXCR2-mediated signaling events |
| 0.0 | 0.9 | PID_NETRIN_PATHWAY | Netrin-mediated signaling events |
| 0.0 | 0.4 | PID_P38_MKK3_6PATHWAY | p38 MAPK signaling pathway |
| 0.0 | 0.2 | PID_S1P_S1P4_PATHWAY | S1P4 pathway |
| 0.0 | 0.3 | SA_B_CELL_RECEPTOR_COMPLEXES | Antigen binding to B cell receptors activates protein tyrosine kinases, such as the Src family, which ultimate activate MAP kinases. |
| 0.0 | 1.9 | PID_NOTCH_PATHWAY | Notch signaling pathway |
| 0.0 | 0.5 | PID_SMAD2_3PATHWAY | Regulation of cytoplasmic and nuclear SMAD2/3 signaling |
| 0.0 | 0.2 | ST_INTERFERON_GAMMA_PATHWAY | Interferon gamma pathway. |
| 0.0 | 1.5 | PID_RB_1PATHWAY | Regulation of retinoblastoma protein |
| 0.0 | 0.5 | PID_NCADHERIN_PATHWAY | N-cadherin signaling events |
| 0.0 | 0.5 | PID_EPHB_FWD_PATHWAY | EPHB forward signaling |
| 0.0 | 0.6 | PID_THROMBIN_PAR1_PATHWAY | PAR1-mediated thrombin signaling events |
| 0.0 | 0.4 | PID_FRA_PATHWAY | Validated transcriptional targets of AP1 family members Fra1 and Fra2 |
| 0.0 | 0.2 | PID_PS1_PATHWAY | Presenilin action in Notch and Wnt signaling |
| 0.0 | 0.4 | PID_ECADHERIN_NASCENT_AJ_PATHWAY | E-cadherin signaling in the nascent adherens junction |
| 0.0 | 0.7 | PID_P53_REGULATION_PATHWAY | p53 pathway |
| 0.0 | 0.2 | PID_AJDISS_2PATHWAY | Posttranslational regulation of adherens junction stability and dissassembly |
| 0.0 | 0.3 | PID_INTEGRIN_A4B1_PATHWAY | Alpha4 beta1 integrin signaling events |
| 0.0 | 0.1 | PID_AVB3_OPN_PATHWAY | Osteopontin-mediated events |
| 0.0 | 1.1 | PID_P53_DOWNSTREAM_PATHWAY | Direct p53 effectors |
| 0.0 | 1.0 | PID_MYC_ACTIV_PATHWAY | Validated targets of C-MYC transcriptional activation |
| 0.0 | 0.3 | PID_IL2_1PATHWAY | IL2-mediated signaling events |
| 0.0 | 0.4 | PID_HNF3A_PATHWAY | FOXA1 transcription factor network |
| 0.0 | 0.3 | PID_TCR_PATHWAY | TCR signaling in naïve CD4+ T cells |
Gene overrepresentation in C2:CP:REACTOME category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.2 | 5.3 | REACTOME_NEF_MEDIATES_DOWN_MODULATION_OF_CELL_SURFACE_RECEPTORS_BY_RECRUITING_THEM_TO_CLATHRIN_ADAPTERS | Genes involved in Nef-mediates down modulation of cell surface receptors by recruiting them to clathrin adapters |
| 0.1 | 2.0 | REACTOME_N_GLYCAN_TRIMMING_IN_THE_ER_AND_CALNEXIN_CALRETICULIN_CYCLE | Genes involved in N-glycan trimming in the ER and Calnexin/Calreticulin cycle |
| 0.1 | 2.2 | REACTOME_INTEGRATION_OF_PROVIRUS | Genes involved in Integration of provirus |
| 0.1 | 1.9 | REACTOME_SYNTHESIS_OF_PIPS_AT_THE_EARLY_ENDOSOME_MEMBRANE | Genes involved in Synthesis of PIPs at the early endosome membrane |
| 0.1 | 1.4 | REACTOME_COPI_MEDIATED_TRANSPORT | Genes involved in COPI Mediated Transport |
| 0.1 | 2.0 | REACTOME_PHOSPHORYLATION_OF_THE_APC_C | Genes involved in Phosphorylation of the APC/C |
| 0.1 | 1.1 | REACTOME_G2_M_DNA_DAMAGE_CHECKPOINT | Genes involved in G2/M DNA damage checkpoint |
| 0.1 | 2.2 | REACTOME_INSULIN_RECEPTOR_RECYCLING | Genes involved in Insulin receptor recycling |
| 0.1 | 4.0 | REACTOME_SIGNALING_BY_ROBO_RECEPTOR | Genes involved in Signaling by Robo receptor |
| 0.1 | 3.5 | REACTOME_ION_TRANSPORT_BY_P_TYPE_ATPASES | Genes involved in Ion transport by P-type ATPases |
| 0.1 | 1.9 | REACTOME_IMMUNOREGULATORY_INTERACTIONS_BETWEEN_A_LYMPHOID_AND_A_NON_LYMPHOID_CELL | Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell |
| 0.1 | 1.0 | REACTOME_IKK_COMPLEX_RECRUITMENT_MEDIATED_BY_RIP1 | Genes involved in IKK complex recruitment mediated by RIP1 |
| 0.1 | 1.0 | REACTOME_ACTIVATION_OF_CHAPERONES_BY_ATF6_ALPHA | Genes involved in Activation of Chaperones by ATF6-alpha |
| 0.1 | 1.4 | REACTOME_PROCESSING_OF_INTRONLESS_PRE_MRNAS | Genes involved in Processing of Intronless Pre-mRNAs |
| 0.1 | 0.9 | REACTOME_CYCLIN_A_B1_ASSOCIATED_EVENTS_DURING_G2_M_TRANSITION | Genes involved in Cyclin A/B1 associated events during G2/M transition |
| 0.1 | 1.2 | REACTOME_GABA_A_RECEPTOR_ACTIVATION | Genes involved in GABA A receptor activation |
| 0.1 | 0.2 | REACTOME_MRNA_CAPPING | Genes involved in mRNA Capping |
| 0.1 | 1.8 | REACTOME_INSULIN_SYNTHESIS_AND_PROCESSING | Genes involved in Insulin Synthesis and Processing |
| 0.1 | 1.6 | REACTOME_MITOCHONDRIAL_TRNA_AMINOACYLATION | Genes involved in Mitochondrial tRNA aminoacylation |
| 0.1 | 1.0 | REACTOME_REGULATED_PROTEOLYSIS_OF_P75NTR | Genes involved in Regulated proteolysis of p75NTR |
| 0.1 | 0.8 | REACTOME_ANTIGEN_PRESENTATION_FOLDING_ASSEMBLY_AND_PEPTIDE_LOADING_OF_CLASS_I_MHC | Genes involved in Antigen Presentation: Folding, assembly and peptide loading of class I MHC |
| 0.1 | 1.3 | REACTOME_SYNTHESIS_OF_PC | Genes involved in Synthesis of PC |
| 0.1 | 0.5 | REACTOME_SYNTHESIS_OF_PIPS_AT_THE_GOLGI_MEMBRANE | Genes involved in Synthesis of PIPs at the Golgi membrane |
| 0.1 | 1.3 | REACTOME_PROLONGED_ERK_ACTIVATION_EVENTS | Genes involved in Prolonged ERK activation events |
| 0.1 | 1.5 | REACTOME_RNA_POL_I_TRANSCRIPTION_INITIATION | Genes involved in RNA Polymerase I Transcription Initiation |
| 0.1 | 0.4 | REACTOME_THE_NLRP3_INFLAMMASOME | Genes involved in The NLRP3 inflammasome |
| 0.0 | 1.5 | REACTOME_NEP_NS2_INTERACTS_WITH_THE_CELLULAR_EXPORT_MACHINERY | Genes involved in NEP/NS2 Interacts with the Cellular Export Machinery |
| 0.0 | 0.0 | REACTOME_NRAGE_SIGNALS_DEATH_THROUGH_JNK | Genes involved in NRAGE signals death through JNK |
| 0.0 | 1.1 | REACTOME_CD28_DEPENDENT_PI3K_AKT_SIGNALING | Genes involved in CD28 dependent PI3K/Akt signaling |
| 0.0 | 0.2 | REACTOME_ADENYLATE_CYCLASE_INHIBITORY_PATHWAY | Genes involved in Adenylate cyclase inhibitory pathway |
| 0.0 | 0.6 | REACTOME_ZINC_TRANSPORTERS | Genes involved in Zinc transporters |
| 0.0 | 0.5 | REACTOME_BMAL1_CLOCK_NPAS2_ACTIVATES_CIRCADIAN_EXPRESSION | Genes involved in BMAL1:CLOCK/NPAS2 Activates Circadian Expression |
| 0.0 | 1.5 | REACTOME_INTRINSIC_PATHWAY_FOR_APOPTOSIS | Genes involved in Intrinsic Pathway for Apoptosis |
| 0.0 | 0.2 | REACTOME_PERK_REGULATED_GENE_EXPRESSION | Genes involved in PERK regulated gene expression |
| 0.0 | 2.0 | REACTOME_METABOLISM_OF_VITAMINS_AND_COFACTORS | Genes involved in Metabolism of vitamins and cofactors |
| 0.0 | 0.9 | REACTOME_SIGNALING_BY_HIPPO | Genes involved in Signaling by Hippo |
| 0.0 | 0.6 | REACTOME_DCC_MEDIATED_ATTRACTIVE_SIGNALING | Genes involved in DCC mediated attractive signaling |
| 0.0 | 0.5 | REACTOME_GLUTAMATE_NEUROTRANSMITTER_RELEASE_CYCLE | Genes involved in Glutamate Neurotransmitter Release Cycle |
| 0.0 | 0.8 | REACTOME_SYNTHESIS_OF_GLYCOSYLPHOSPHATIDYLINOSITOL_GPI | Genes involved in Synthesis of glycosylphosphatidylinositol (GPI) |
| 0.0 | 0.5 | REACTOME_CTNNB1_PHOSPHORYLATION_CASCADE | Genes involved in Beta-catenin phosphorylation cascade |
| 0.0 | 0.1 | REACTOME_ADVANCED_GLYCOSYLATION_ENDPRODUCT_RECEPTOR_SIGNALING | Genes involved in Advanced glycosylation endproduct receptor signaling |
| 0.0 | 0.4 | REACTOME_TRAF3_DEPENDENT_IRF_ACTIVATION_PATHWAY | Genes involved in TRAF3-dependent IRF activation pathway |
| 0.0 | 0.6 | REACTOME_RNA_POL_III_TRANSCRIPTION_INITIATION_FROM_TYPE_3_PROMOTER | Genes involved in RNA Polymerase III Transcription Initiation From Type 3 Promoter |
| 0.0 | 2.1 | REACTOME_TRANSCRIPTIONAL_REGULATION_OF_WHITE_ADIPOCYTE_DIFFERENTIATION | Genes involved in Transcriptional Regulation of White Adipocyte Differentiation |
| 0.0 | 0.5 | REACTOME_PKA_MEDIATED_PHOSPHORYLATION_OF_CREB | Genes involved in PKA-mediated phosphorylation of CREB |
| 0.0 | 0.7 | REACTOME_EGFR_DOWNREGULATION | Genes involved in EGFR downregulation |
| 0.0 | 0.1 | REACTOME_DOWNSTREAM_TCR_SIGNALING | Genes involved in Downstream TCR signaling |
| 0.0 | 0.0 | REACTOME_ABORTIVE_ELONGATION_OF_HIV1_TRANSCRIPT_IN_THE_ABSENCE_OF_TAT | Genes involved in Abortive elongation of HIV-1 transcript in the absence of Tat |
| 0.0 | 0.0 | REACTOME_CTLA4_INHIBITORY_SIGNALING | Genes involved in CTLA4 inhibitory signaling |
| 0.0 | 1.3 | REACTOME_PROTEIN_FOLDING | Genes involved in Protein folding |
| 0.0 | 0.2 | REACTOME_PROTEOLYTIC_CLEAVAGE_OF_SNARE_COMPLEX_PROTEINS | Genes involved in Proteolytic cleavage of SNARE complex proteins |
| 0.0 | 0.1 | REACTOME_PASSIVE_TRANSPORT_BY_AQUAPORINS | Genes involved in Passive Transport by Aquaporins |
| 0.0 | 0.5 | REACTOME_SIGNALING_BY_BMP | Genes involved in Signaling by BMP |
| 0.0 | 0.6 | REACTOME_PPARA_ACTIVATES_GENE_EXPRESSION | Genes involved in PPARA Activates Gene Expression |
| 0.0 | 0.7 | REACTOME_GOLGI_ASSOCIATED_VESICLE_BIOGENESIS | Genes involved in Golgi Associated Vesicle Biogenesis |
| 0.0 | 0.3 | REACTOME_GLYCOGEN_BREAKDOWN_GLYCOGENOLYSIS | Genes involved in Glycogen breakdown (glycogenolysis) |
| 0.0 | 0.3 | REACTOME_PRE_NOTCH_TRANSCRIPTION_AND_TRANSLATION | Genes involved in Pre-NOTCH Transcription and Translation |
| 0.0 | 0.2 | REACTOME_REGULATION_OF_HYPOXIA_INDUCIBLE_FACTOR_HIF_BY_OXYGEN | Genes involved in Regulation of Hypoxia-inducible Factor (HIF) by Oxygen |
| 0.0 | 0.6 | REACTOME_AQUAPORIN_MEDIATED_TRANSPORT | Genes involved in Aquaporin-mediated transport |
| 0.0 | 0.3 | REACTOME_SYNTHESIS_OF_PIPS_AT_THE_PLASMA_MEMBRANE | Genes involved in Synthesis of PIPs at the plasma membrane |
| 0.0 | 0.2 | REACTOME_CHYLOMICRON_MEDIATED_LIPID_TRANSPORT | Genes involved in Chylomicron-mediated lipid transport |
| 0.0 | 0.1 | REACTOME_SIGNALING_BY_NOTCH4 | Genes involved in Signaling by NOTCH4 |
| 0.0 | 0.1 | REACTOME_DESTABILIZATION_OF_MRNA_BY_AUF1_HNRNP_D0 | Genes involved in Destabilization of mRNA by AUF1 (hnRNP D0) |
| 0.0 | 0.1 | REACTOME_METAL_ION_SLC_TRANSPORTERS | Genes involved in Metal ion SLC transporters |
| 0.0 | 1.4 | REACTOME_GENERIC_TRANSCRIPTION_PATHWAY | Genes involved in Generic Transcription Pathway |
| 0.0 | 0.0 | REACTOME_GENERATION_OF_SECOND_MESSENGER_MOLECULES | Genes involved in Generation of second messenger molecules |
| 0.0 | 0.2 | REACTOME_SYNTHESIS_SECRETION_AND_DEACYLATION_OF_GHRELIN | Genes involved in Synthesis, Secretion, and Deacylation of Ghrelin |
| 0.0 | 0.1 | REACTOME_INHIBITION_OF_REPLICATION_INITIATION_OF_DAMAGED_DNA_BY_RB1_E2F1 | Genes involved in Inhibition of replication initiation of damaged DNA by RB1/E2F1 |
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