Motif ID: Etv6

Z-value: 0.595


Transcription factors associated with Etv6:

Gene SymbolEntrez IDGene Name
Etv6 ENSMUSG00000030199.10 Etv6

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Etv6mm10_v2_chr6_+_134035691_134035717-0.382.0e-02Click!


Activity profile for motif Etv6.

activity profile for motif Etv6


Sorted Z-values histogram for motif Etv6

Sorted Z-values for motif Etv6



Network of associatons between targets according to the STRING database.



First level regulatory network of Etv6

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr7_-_4546567 1.211 ENSMUST00000065957.5
Syt5
synaptotagmin V
chr1_+_33669816 1.113 ENSMUST00000051203.5
1700001G17Rik
RIKEN cDNA 1700001G17 gene
chr2_+_168230597 0.827 ENSMUST00000099071.3
Mocs3
molybdenum cofactor synthesis 3
chr18_+_62548911 0.782 ENSMUST00000055725.4
ENSMUST00000162365.1
Spink10

serine peptidase inhibitor, Kazal type 10

chr11_-_84819450 0.767 ENSMUST00000018549.7
Mrm1
mitochondrial rRNA methyltransferase 1 homolog (S. cerevisiae)
chrX_+_7884244 0.655 ENSMUST00000115663.3
Slc35a2
solute carrier family 35 (UDP-galactose transporter), member A2
chr5_-_31220491 0.646 ENSMUST00000031032.7
Ppm1g
protein phosphatase 1G (formerly 2C), magnesium-dependent, gamma isoform
chr3_+_95217417 0.603 ENSMUST00000181819.1
Gm16740
predicted gene, 16740
chr17_+_35135463 0.569 ENSMUST00000173535.1
ENSMUST00000173952.1
Bag6

BCL2-associated athanogene 6

chr6_-_120822680 0.562 ENSMUST00000019354.8
Atp6v1e1
ATPase, H+ transporting, lysosomal V1 subunit E1
chr11_+_5955693 0.557 ENSMUST00000002818.8
Ykt6
YKT6 homolog (S. Cerevisiae)
chr1_-_183221529 0.545 ENSMUST00000003035.5
Disp1
dispatched homolog 1 (Drosophila)
chr17_+_20945311 0.545 ENSMUST00000007708.7
Ppp2r1a
protein phosphatase 2 (formerly 2A), regulatory subunit A (PR 65), alpha isoform
chrX_+_7884022 0.543 ENSMUST00000115660.4
Slc35a2
solute carrier family 35 (UDP-galactose transporter), member A2
chr5_-_115348953 0.541 ENSMUST00000040154.8
Cox6a1
cytochrome c oxidase subunit VIa polypeptide 1
chr15_-_98145625 0.519 ENSMUST00000059112.5
Asb8
ankyrin repeat and SOCS box-containing 8
chr1_+_58586381 0.515 ENSMUST00000027193.8
Ndufb3
NADH dehydrogenase (ubiquinone) 1 beta subcomplex 3
chr1_-_33669745 0.515 ENSMUST00000027312.9
Prim2
DNA primase, p58 subunit
chr9_+_107563246 0.514 ENSMUST00000010198.3
Tusc2
tumor suppressor candidate 2
chr3_-_94886945 0.512 ENSMUST00000005923.6
Psmb4
proteasome (prosome, macropain) subunit, beta type 4
chr17_+_35135695 0.511 ENSMUST00000174478.1
ENSMUST00000174281.2
ENSMUST00000173550.1
Bag6


BCL2-associated athanogene 6


chr8_+_107056870 0.509 ENSMUST00000034392.5
ENSMUST00000170962.1
Nip7

nuclear import 7 homolog (S. cerevisiae)

chr15_+_5185700 0.502 ENSMUST00000081640.5
Ttc33
tetratricopeptide repeat domain 33
chr15_+_12824815 0.499 ENSMUST00000169061.1
Drosha
drosha, ribonuclease type III
chr9_-_78489141 0.497 ENSMUST00000154207.1
Eef1a1
eukaryotic translation elongation factor 1 alpha 1
chr5_+_143758293 0.496 ENSMUST00000180951.1
D130017N08Rik
RIKEN cDNA D130017N08 gene
chr11_+_120098910 0.495 ENSMUST00000106223.2
1810043H04Rik
RIKEN cDNA 1810043H04 gene
chr19_-_45660312 0.490 ENSMUST00000046869.4
Fbxw4
F-box and WD-40 domain protein 4
chr13_+_46669517 0.488 ENSMUST00000099547.3
C78339
expressed sequence C78339
chr10_-_67285180 0.483 ENSMUST00000159002.1
ENSMUST00000077839.6
Nrbf2

nuclear receptor binding factor 2

chr15_+_58933774 0.482 ENSMUST00000022980.3
Ndufb9
NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 9
chrX_+_7884321 0.480 ENSMUST00000096514.3
ENSMUST00000123277.1
Slc35a2

solute carrier family 35 (UDP-galactose transporter), member A2

chr14_-_31001588 0.479 ENSMUST00000162092.1
ENSMUST00000160342.1
Spcs1

signal peptidase complex subunit 1 homolog (S. cerevisiae)

chr3_-_95871367 0.475 ENSMUST00000142437.1
ENSMUST00000067298.4
Mrps21

mitochondrial ribosomal protein S21

chr4_+_44012638 0.472 ENSMUST00000107847.3
ENSMUST00000170241.1
Clta

clathrin, light polypeptide (Lca)

chr15_-_98145698 0.471 ENSMUST00000123626.1
Asb8
ankyrin repeat and SOCS box-containing 8
chr9_-_79759849 0.471 ENSMUST00000034881.6
Cox7a2
cytochrome c oxidase subunit VIIa 2
chr4_+_44012661 0.470 ENSMUST00000107849.3
ENSMUST00000107851.3
ENSMUST00000107845.3
Clta


clathrin, light polypeptide (Lca)


chr9_+_48450327 0.464 ENSMUST00000165252.1
Gm5616
predicted gene 5616
chr5_-_38561658 0.446 ENSMUST00000005234.9
Wdr1
WD repeat domain 1
chr17_+_35135174 0.439 ENSMUST00000166426.2
ENSMUST00000025250.7
Bag6

BCL2-associated athanogene 6

chr13_+_20090538 0.438 ENSMUST00000072519.5
Elmo1
engulfment and cell motility 1
chr5_-_135744206 0.432 ENSMUST00000153399.1
ENSMUST00000043378.2
Tmem120a

transmembrane protein 120A

chr11_-_120457936 0.428 ENSMUST00000137632.1
ENSMUST00000044007.2
Oxld1

oxidoreductase like domain containing 1

chr5_-_110269816 0.428 ENSMUST00000059229.9
ENSMUST00000112505.2
Pgam5

phosphoglycerate mutase family member 5

chr15_-_82047579 0.425 ENSMUST00000166578.1
ENSMUST00000080622.7
Nhp2l1

NHP2 non-histone chromosome protein 2-like 1 (S. cerevisiae)

chr13_-_74208661 0.423 ENSMUST00000035934.5
Exoc3
exocyst complex component 3
chr11_+_114668524 0.422 ENSMUST00000106602.3
ENSMUST00000077915.3
ENSMUST00000106599.1
ENSMUST00000082092.4
Rpl38



ribosomal protein L38



chr3_+_89430261 0.422 ENSMUST00000060061.4
Pygo2
pygopus 2
chr5_-_139826407 0.419 ENSMUST00000182839.1
Gm26938
predicted gene, 26938
chr4_-_116017854 0.416 ENSMUST00000049095.5
Faah
fatty acid amide hydrolase
chr15_+_12824841 0.416 ENSMUST00000090292.5
Drosha
drosha, ribonuclease type III
chr17_+_46711459 0.409 ENSMUST00000002840.8
Pex6
peroxisomal biogenesis factor 6
chr9_+_20644792 0.404 ENSMUST00000162303.1
ENSMUST00000161486.1
Ubl5

ubiquitin-like 5

chr19_+_10895225 0.402 ENSMUST00000025642.7
Prpf19
PRP19/PSO4 pre-mRNA processing factor 19 homolog (S. cerevisiae)
chr13_+_20090500 0.401 ENSMUST00000165249.2
Elmo1
engulfment and cell motility 1
chr1_-_125435694 0.401 ENSMUST00000178474.1
ENSMUST00000027579.10
Actr3

ARP3 actin-related protein 3

chr1_+_179546303 0.399 ENSMUST00000040706.8
Cnst
consortin, connexin sorting protein
chr15_-_34443508 0.399 ENSMUST00000079735.5
Rpl30
ribosomal protein L30
chr8_-_72571033 0.398 ENSMUST00000058733.8
ENSMUST00000167290.1
Smim7

small integral membrane protein 7

chr9_+_108508005 0.398 ENSMUST00000006838.8
ENSMUST00000134939.1
Qars

glutaminyl-tRNA synthetase

chr12_-_84970814 0.395 ENSMUST00000165886.1
ENSMUST00000167448.1
ENSMUST00000043169.7
Arel1


apoptosis resistant E3 ubiquitin protein ligase 1


chr9_+_108460518 0.392 ENSMUST00000061209.5
Ccdc71
coiled-coil domain containing 71
chr5_-_139826837 0.388 ENSMUST00000182602.1
ENSMUST00000031531.7
Psmg3

proteasome (prosome, macropain) assembly chaperone 3

chr2_+_29935413 0.388 ENSMUST00000019859.8
Gle1
GLE1 RNA export mediator (yeast)
chr15_+_5185519 0.386 ENSMUST00000118193.1
ENSMUST00000022751.8
Ttc33

tetratricopeptide repeat domain 33

chr17_+_35135196 0.383 ENSMUST00000172571.1
ENSMUST00000173491.1
Bag6

BCL2-associated athanogene 6

chr3_-_88425094 0.382 ENSMUST00000168755.1
ENSMUST00000057935.6
Slc25a44

solute carrier family 25, member 44

chr5_-_137533170 0.380 ENSMUST00000168746.1
ENSMUST00000170293.1
Gnb2

guanine nucleotide binding protein (G protein), beta 2

chr9_+_20644851 0.376 ENSMUST00000161882.1
Ubl5
ubiquitin-like 5
chr14_-_55671873 0.373 ENSMUST00000163750.1
ENSMUST00000010520.8
Nedd8

neural precursor cell expressed, developmentally down-regulated gene 8

chr8_+_113635550 0.370 ENSMUST00000179926.1
Mon1b
MON1 homolog b (yeast)
chr5_+_147860615 0.368 ENSMUST00000031654.6
Pomp
proteasome maturation protein
chr5_-_138263942 0.368 ENSMUST00000048421.7
ENSMUST00000164203.1
BC037034
BC037034
cDNA sequence BC037034
cDNA sequence BC037034
chr19_-_6084873 0.365 ENSMUST00000160977.1
ENSMUST00000159859.1
Zfpl1

zinc finger like protein 1

chr7_+_4792874 0.359 ENSMUST00000032597.5
ENSMUST00000078432.4
Rpl28

ribosomal protein L28

chr13_+_4191163 0.355 ENSMUST00000021634.2
Akr1c13
aldo-keto reductase family 1, member C13
chrX_-_94212638 0.349 ENSMUST00000113922.1
Eif2s3x
eukaryotic translation initiation factor 2, subunit 3, structural gene X-linked
chr14_-_31001311 0.347 ENSMUST00000161219.1
ENSMUST00000182501.1
Spcs1

signal peptidase complex subunit 1 homolog (S. cerevisiae)

chr11_-_16508069 0.347 ENSMUST00000109641.1
Sec61g
SEC61, gamma subunit
chr7_+_19149722 0.346 ENSMUST00000049294.2
Snrpd2
small nuclear ribonucleoprotein D2
chr18_+_31789120 0.343 ENSMUST00000025106.3
Polr2d
polymerase (RNA) II (DNA directed) polypeptide D
chr9_-_21149894 0.343 ENSMUST00000019615.9
Cdc37
cell division cycle 37
chr4_-_107178282 0.340 ENSMUST00000058585.7
Tceanc2
transcription elongation factor A (SII) N-terminal and central domain containing 2
chr12_+_102757965 0.339 ENSMUST00000046404.6
Ubr7
ubiquitin protein ligase E3 component n-recognin 7 (putative)
chr8_+_84148252 0.339 ENSMUST00000093375.4
4930432K21Rik
RIKEN cDNA 4930432K21 gene
chr7_-_105744312 0.338 ENSMUST00000141116.1
Taf10
TAF10 RNA polymerase II, TATA box binding protein (TBP)-associated factor
chr15_-_85811644 0.338 ENSMUST00000144067.1
ENSMUST00000134631.1
ENSMUST00000154814.1
ENSMUST00000071876.6
ENSMUST00000150995.1
Cdpf1




cysteine rich, DPF motif domain containing 1




chr13_+_69809863 0.334 ENSMUST00000022089.8
Med10
mediator of RNA polymerase II transcription, subunit 10 homolog (NUT2, S. cerevisiae)
chr8_-_107056650 0.327 ENSMUST00000034391.3
ENSMUST00000095517.5
Cog8

component of oligomeric golgi complex 8

chr4_+_155943824 0.325 ENSMUST00000103175.1
ENSMUST00000166489.1
ENSMUST00000024056.3
ENSMUST00000136492.1
ENSMUST00000105583.2
ENSMUST00000152536.1
Ube2j2





ubiquitin-conjugating enzyme E2J 2





chr19_-_6084941 0.323 ENSMUST00000025707.2
ENSMUST00000160712.1
Zfpl1

zinc finger like protein 1

chr7_+_127233044 0.323 ENSMUST00000106312.3
Zfp553
zinc finger protein 553
chr12_+_84970897 0.320 ENSMUST00000021669.8
ENSMUST00000171040.1
Fcf1

FCF1 small subunit (SSU) processome component homolog (S. cerevisiae)

chr15_+_78877172 0.318 ENSMUST00000041587.7
Gga1
golgi associated, gamma adaptin ear containing, ARF binding protein 1
chr12_-_78861636 0.316 ENSMUST00000021536.7
Atp6v1d
ATPase, H+ transporting, lysosomal V1 subunit D
chr17_+_27839974 0.312 ENSMUST00000071006.7
Snrpc
U1 small nuclear ribonucleoprotein C
chr7_+_127233227 0.309 ENSMUST00000056232.6
Zfp553
zinc finger protein 553
chr2_-_90904827 0.309 ENSMUST00000005647.3
Ndufs3
NADH dehydrogenase (ubiquinone) Fe-S protein 3
chr4_-_40948196 0.309 ENSMUST00000030125.4
ENSMUST00000108089.1
Bag1

BCL2-associated athanogene 1

chr2_-_30286312 0.307 ENSMUST00000100219.3
Dolk
dolichol kinase
chr8_-_70510322 0.307 ENSMUST00000140679.1
ENSMUST00000129909.1
ENSMUST00000081940.4
Uba52


ubiquitin A-52 residue ribosomal protein fusion product 1


chrX_+_20703906 0.306 ENSMUST00000033383.2
Usp11
ubiquitin specific peptidase 11
chr4_-_124851152 0.305 ENSMUST00000185036.1
1110065P20Rik
RIKEN cDNA 1110065P20 gene
chrX_-_134541847 0.300 ENSMUST00000054213.4
Timm8a1
translocase of inner mitochondrial membrane 8A1
chr11_-_16508149 0.299 ENSMUST00000109642.1
Sec61g
SEC61, gamma subunit
chr3_-_90213577 0.294 ENSMUST00000170122.2
Rps27
ribosomal protein S27
chr4_-_98383232 0.293 ENSMUST00000143116.1
ENSMUST00000030292.5
ENSMUST00000102793.4
Tm2d1


TM2 domain containing 1


chr17_-_15498263 0.293 ENSMUST00000014913.9
Psmb1
proteasome (prosome, macropain) subunit, beta type 1
chr4_-_133277730 0.292 ENSMUST00000105907.2
Tmem222
transmembrane protein 222
chr3_+_96172327 0.291 ENSMUST00000076372.4
Sf3b4
splicing factor 3b, subunit 4
chr7_-_125707735 0.291 ENSMUST00000055506.7
Gtf3c1
general transcription factor III C 1
chr9_-_43105718 0.291 ENSMUST00000165665.1
Arhgef12
Rho guanine nucleotide exchange factor (GEF) 12
chr1_+_167308649 0.289 ENSMUST00000097473.4
Tmco1
transmembrane and coiled-coil domains 1
chr15_-_34443209 0.287 ENSMUST00000009039.5
Rpl30
ribosomal protein L30
chr2_+_180257373 0.285 ENSMUST00000059080.6
Rps21
ribosomal protein S21
chr15_-_51865448 0.284 ENSMUST00000022925.8
Eif3h
eukaryotic translation initiation factor 3, subunit H
chr10_+_13008442 0.284 ENSMUST00000105139.3
Sf3b5
splicing factor 3b, subunit 5
chr12_-_102757765 0.282 ENSMUST00000173969.1
ENSMUST00000179263.1
ENSMUST00000046456.6
ENSMUST00000179306.1
AK010878


RP24-234J3.4
cDNA sequence AK010878


Protein AK010878
chr9_-_20492691 0.281 ENSMUST00000169269.1
ENSMUST00000164250.1
Zfp426

zinc finger protein 426

chr11_-_96916407 0.279 ENSMUST00000130774.1
Cdk5rap3
CDK5 regulatory subunit associated protein 3
chr5_-_116024475 0.279 ENSMUST00000111999.1
Prkab1
protein kinase, AMP-activated, beta 1 non-catalytic subunit
chr8_+_113635787 0.278 ENSMUST00000035777.8
Mon1b
MON1 homolog b (yeast)
chr2_+_90904740 0.277 ENSMUST00000111464.1
ENSMUST00000090682.3
Kbtbd4

kelch repeat and BTB (POZ) domain containing 4

chr9_-_18473559 0.276 ENSMUST00000034647.4
Zfp558
zinc finger protein 558
chr11_-_97150025 0.275 ENSMUST00000118375.1
Tbkbp1
TBK1 binding protein 1
chr19_-_27429807 0.275 ENSMUST00000076219.4
D19Bwg1357e
DNA segment, Chr 19, Brigham & Women's Genetics 1357 expressed
chr5_-_138264013 0.275 ENSMUST00000161604.1
ENSMUST00000163268.1
BC037034
BC037034
cDNA sequence BC037034
cDNA sequence BC037034
chr7_-_45434590 0.274 ENSMUST00000107771.3
ENSMUST00000141761.1
Ruvbl2

RuvB-like protein 2

chr6_-_113377866 0.273 ENSMUST00000032410.7
Tada3
transcriptional adaptor 3
chr11_-_115699461 0.273 ENSMUST00000106497.1
Grb2
growth factor receptor bound protein 2
chr17_-_29347902 0.271 ENSMUST00000095427.4
ENSMUST00000118366.1
Mtch1

mitochondrial carrier homolog 1 (C. elegans)

chr16_+_3872368 0.267 ENSMUST00000151988.1
Naa60
N(alpha)-acetyltransferase 60, NatF catalytic subunit
chr4_-_155086271 0.266 ENSMUST00000030914.3
Rer1
RER1 retention in endoplasmic reticulum 1 homolog (S. cerevisiae)
chr6_-_113377712 0.265 ENSMUST00000113107.1
ENSMUST00000113106.1
Tada3

transcriptional adaptor 3

chr19_-_5366626 0.259 ENSMUST00000025762.8
Banf1
barrier to autointegration factor 1
chr6_+_113378113 0.259 ENSMUST00000171058.1
ENSMUST00000156898.1
Arpc4

actin related protein 2/3 complex, subunit 4

chr5_-_145140238 0.255 ENSMUST00000031627.8
Pdap1
PDGFA associated protein 1
chr7_+_125707945 0.255 ENSMUST00000148701.1
D430042O09Rik
RIKEN cDNA D430042O09 gene
chr7_+_5080214 0.254 ENSMUST00000098845.3
ENSMUST00000146317.1
ENSMUST00000153169.1
ENSMUST00000045277.6
Epn1



epsin 1



chr12_+_69241832 0.254 ENSMUST00000063445.6
Klhdc1
kelch domain containing 1
chr15_-_12824605 0.252 ENSMUST00000057256.3
6030458C11Rik
RIKEN cDNA 6030458C11 gene
chr2_-_30967859 0.252 ENSMUST00000028200.8
Tor1a
torsin family 1, member A (torsin A)
chr5_-_31202215 0.252 ENSMUST00000176245.1
ENSMUST00000177310.1
ENSMUST00000114590.1
Zfp513


zinc finger protein 513


chr4_+_118409331 0.252 ENSMUST00000084319.4
ENSMUST00000106384.3
ENSMUST00000126089.1
ENSMUST00000073881.1
ENSMUST00000019229.8
ENSMUST00000144577.1
Med8





mediator of RNA polymerase II transcription, subunit 8 homolog (yeast)





chr1_+_134494628 0.250 ENSMUST00000047978.7
Rabif
RAB interacting factor
chr11_+_120467635 0.250 ENSMUST00000140862.1
ENSMUST00000106205.1
ENSMUST00000106203.1
ENSMUST00000026900.7
Hgs



HGF-regulated tyrosine kinase substrate



chr13_-_58128542 0.250 ENSMUST00000007980.6
Hnrnpa0
heterogeneous nuclear ribonucleoprotein A0
chr8_+_84148025 0.248 ENSMUST00000143833.1
ENSMUST00000118856.1
4930432K21Rik

RIKEN cDNA 4930432K21 gene

chr11_-_35834492 0.247 ENSMUST00000018992.3
Rars
arginyl-tRNA synthetase
chrX_-_94212685 0.245 ENSMUST00000050328.8
Eif2s3x
eukaryotic translation initiation factor 2, subunit 3, structural gene X-linked
chr19_-_6084679 0.242 ENSMUST00000161548.1
Zfpl1
zinc finger like protein 1
chr7_-_46919915 0.242 ENSMUST00000143413.1
ENSMUST00000014546.8
Tsg101

tumor susceptibility gene 101

chr5_+_124629050 0.242 ENSMUST00000037865.8
Atp6v0a2
ATPase, H+ transporting, lysosomal V0 subunit A2
chr9_+_56418624 0.241 ENSMUST00000034879.3
Hmg20a
high mobility group 20A
chr11_-_115699307 0.241 ENSMUST00000106499.1
Grb2
growth factor receptor bound protein 2
chr4_-_116807574 0.240 ENSMUST00000030451.3
Toe1
target of EGR1, member 1 (nuclear)
chr10_+_79669410 0.231 ENSMUST00000020552.5
Tpgs1
tubulin polyglutamylase complex subunit 1
chr17_-_35121030 0.229 ENSMUST00000174306.1
Csnk2b
casein kinase 2, beta polypeptide
chr8_-_94601720 0.228 ENSMUST00000034226.6
Fam192a
family with sequence similarity 192, member A
chr17_+_46110982 0.227 ENSMUST00000024763.3
ENSMUST00000123646.1
Mrps18a

mitochondrial ribosomal protein S18A

chr3_+_95658771 0.225 ENSMUST00000178686.1
Mcl1
myeloid cell leukemia sequence 1
chr12_+_78861693 0.223 ENSMUST00000071230.7
Eif2s1
eukaryotic translation initiation factor 2, subunit 1 alpha
chr11_-_96916366 0.223 ENSMUST00000144731.1
ENSMUST00000127048.1
Cdk5rap3

CDK5 regulatory subunit associated protein 3

chr4_+_107178399 0.223 ENSMUST00000030361.4
ENSMUST00000128123.1
ENSMUST00000106753.1
Tmem59


transmembrane protein 59


chr7_+_5062143 0.223 ENSMUST00000005041.7
U2af2
U2 small nuclear ribonucleoprotein auxiliary factor (U2AF) 2
chr4_-_116807532 0.222 ENSMUST00000106455.1
Toe1
target of EGR1, member 1 (nuclear)
chr9_+_40192308 0.221 ENSMUST00000026693.7
ENSMUST00000168832.1
Zfp202

zinc finger protein 202

chr7_-_67645195 0.219 ENSMUST00000032775.5
ENSMUST00000053950.2
Lrrc28

leucine rich repeat containing 28

chr1_+_45795485 0.219 ENSMUST00000147308.1
Wdr75
WD repeat domain 75
chr14_+_55672235 0.219 ENSMUST00000002397.5
Gmpr2
guanosine monophosphate reductase 2
chr7_+_80261202 0.218 ENSMUST00000117989.1
Ngrn
neugrin, neurite outgrowth associated
chr9_+_46273064 0.218 ENSMUST00000156440.1
ENSMUST00000034583.6
ENSMUST00000114552.3
Zfp259


zinc finger protein 259


chr9_-_22117123 0.217 ENSMUST00000013966.6
Elof1
elongation factor 1 homolog (ELF1, S. cerevisiae)
chr11_-_51635870 0.216 ENSMUST00000001081.3
Rmnd5b
required for meiotic nuclear division 5 homolog B (S. cerevisiae)
chr11_-_120098673 0.216 ENSMUST00000093901.5
ENSMUST00000026442.4
ENSMUST00000106225.3
Enthd2


ENTH domain containing 2


chr2_-_84715160 0.215 ENSMUST00000035840.5
Zdhhc5
zinc finger, DHHC domain containing 5
chr1_+_118321834 0.214 ENSMUST00000027626.6
ENSMUST00000112688.3
Mki67ip

Mki67 (FHA domain) interacting nucleolar phosphoprotein

chr16_+_31948513 0.214 ENSMUST00000023460.6
ENSMUST00000115178.1
Ncbp2

nuclear cap binding protein subunit 2

chr4_+_139192899 0.213 ENSMUST00000102508.3
ENSMUST00000131912.1
ENSMUST00000102507.3
Capzb


capping protein (actin filament) muscle Z-line, beta


chr8_-_70510552 0.212 ENSMUST00000125184.1
Uba52
ubiquitin A-52 residue ribosomal protein fusion product 1
chr2_+_39008076 0.210 ENSMUST00000112862.1
ENSMUST00000090993.5
Arpc5l

actin related protein 2/3 complex, subunit 5-like

chrX_+_73411096 0.210 ENSMUST00000033740.5
Zfp92
zinc finger protein 92
chr1_-_36244245 0.209 ENSMUST00000046875.7
Uggt1
UDP-glucose glycoprotein glucosyltransferase 1
chr11_-_118290188 0.208 ENSMUST00000106296.2
ENSMUST00000092382.3
Usp36

ubiquitin specific peptidase 36

chr19_-_5366285 0.207 ENSMUST00000170010.1
Banf1
barrier to autointegration factor 1
chr8_+_83652670 0.207 ENSMUST00000019577.8
Gipc1
GIPC PDZ domain containing family, member 1
chr8_-_107588392 0.207 ENSMUST00000044106.4
Psmd7
proteasome (prosome, macropain) 26S subunit, non-ATPase, 7
chr11_-_119300070 0.206 ENSMUST00000026667.8
Eif4a3
eukaryotic translation initiation factor 4A3
chr11_-_96916448 0.204 ENSMUST00000103152.4
Cdk5rap3
CDK5 regulatory subunit associated protein 3
chr14_+_55591708 0.202 ENSMUST00000019443.8
Rnf31
ring finger protein 31
chr11_+_88204396 0.200 ENSMUST00000118784.1
ENSMUST00000139170.1
ENSMUST00000107915.3
ENSMUST00000144070.1
Mrps23



mitochondrial ribosomal protein S23



chr11_+_88204380 0.200 ENSMUST00000024486.7
Mrps23
mitochondrial ribosomal protein S23
chr17_-_35121173 0.199 ENSMUST00000174024.1
Csnk2b
casein kinase 2, beta polypeptide
chr1_+_91250311 0.197 ENSMUST00000059743.5
ENSMUST00000178627.1
ENSMUST00000171165.1
Ube2f


ubiquitin-conjugating enzyme E2F (putative)


chr11_-_97041395 0.197 ENSMUST00000021251.6
Lrrc46
leucine rich repeat containing 46
chr11_-_118290167 0.195 ENSMUST00000144153.1
Usp36
ubiquitin specific peptidase 36
chr18_-_60848911 0.194 ENSMUST00000177172.1
ENSMUST00000175934.1
ENSMUST00000176630.1
Tcof1


Treacher Collins Franceschetti syndrome 1, homolog


chrX_+_144317799 0.193 ENSMUST00000070801.4
Alg13
asparagine-linked glycosylation 13
chr11_+_68901538 0.190 ENSMUST00000073471.6
ENSMUST00000101014.2
ENSMUST00000128952.1
ENSMUST00000167436.1
Rpl26



ribosomal protein L26




Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.9 GO:0036506 maintenance of unfolded protein(GO:0036506) tail-anchored membrane protein insertion into ER membrane(GO:0071816) maintenance of unfolded protein involved in ERAD pathway(GO:1904378)
0.2 0.6 GO:0019085 early viral transcription(GO:0019085)
0.2 0.8 GO:0018307 tRNA wobble position uridine thiolation(GO:0002143) enzyme active site formation(GO:0018307)
0.2 0.5 GO:1903538 meiotic sister chromatid cohesion, centromeric(GO:0051754) meiotic cell cycle process involved in oocyte maturation(GO:1903537) regulation of meiotic cell cycle process involved in oocyte maturation(GO:1903538)
0.2 0.5 GO:0016344 meiotic chromosome movement towards spindle pole(GO:0016344)
0.2 0.5 GO:0070944 neutrophil mediated killing of bacterium(GO:0070944)
0.2 0.5 GO:0019043 establishment of viral latency(GO:0019043)
0.1 0.4 GO:0016561 protein import into peroxisome matrix, translocation(GO:0016561)
0.1 0.4 GO:0090004 positive regulation of Golgi to plasma membrane protein transport(GO:0042998) positive regulation of establishment of protein localization to plasma membrane(GO:0090004)
0.1 0.9 GO:0030422 production of siRNA involved in RNA interference(GO:0030422)
0.1 0.5 GO:0006269 DNA replication, synthesis of RNA primer(GO:0006269)
0.1 0.3 GO:0031990 mRNA export from nucleus in response to heat stress(GO:0031990)
0.1 0.3 GO:1904569 regulation of selenocysteine incorporation(GO:1904569)
0.1 0.4 GO:0030043 actin filament fragmentation(GO:0030043)
0.1 0.8 GO:0060046 regulation of acrosome reaction(GO:0060046)
0.1 0.3 GO:0090202 transcriptional activation by promoter-enhancer looping(GO:0071733) regulation of estrogen receptor binding(GO:0071898) negative regulation of estrogen receptor binding(GO:0071899) gene looping(GO:0090202) dsDNA loop formation(GO:0090579)
0.1 0.6 GO:0000447 endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000447)
0.1 0.3 GO:1903750 MHC class I biosynthetic process(GO:0045341) regulation of MHC class I biosynthetic process(GO:0045343) positive regulation of MHC class I biosynthetic process(GO:0045345) positive regulation of NK T cell activation(GO:0051135) regulation of intrinsic apoptotic signaling pathway in response to hydrogen peroxide(GO:1903750) negative regulation of intrinsic apoptotic signaling pathway in response to hydrogen peroxide(GO:1903751)
0.1 0.2 GO:1903774 positive regulation of viral budding via host ESCRT complex(GO:1903774)
0.1 0.4 GO:0000393 spliceosomal conformational changes to generate catalytic conformation(GO:0000393)
0.1 0.2 GO:2000157 regulation of protein K48-linked deubiquitination(GO:1903093) negative regulation of protein K48-linked deubiquitination(GO:1903094) negative regulation of ubiquitin-specific protease activity(GO:2000157)
0.1 0.7 GO:0071569 protein ufmylation(GO:0071569)
0.1 0.4 GO:1903378 positive regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway(GO:1903378)
0.1 0.2 GO:0090285 negative regulation of protein glycosylation in Golgi(GO:0090285)
0.1 0.6 GO:0006123 mitochondrial electron transport, cytochrome c to oxygen(GO:0006123)
0.1 0.5 GO:0002862 negative regulation of inflammatory response to antigenic stimulus(GO:0002862)
0.1 0.2 GO:1902162 regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator(GO:1902162)
0.1 0.2 GO:0006420 arginyl-tRNA aminoacylation(GO:0006420)
0.1 0.4 GO:0048318 axial mesoderm development(GO:0048318)
0.1 0.5 GO:0090043 regulation of tubulin deacetylation(GO:0090043)
0.1 0.8 GO:0033211 adiponectin-activated signaling pathway(GO:0033211)
0.1 0.3 GO:0006384 transcription initiation from RNA polymerase III promoter(GO:0006384)
0.1 0.2 GO:1901069 guanosine-containing compound catabolic process(GO:1901069)
0.1 0.3 GO:0035878 nail development(GO:0035878)
0.1 0.3 GO:2000672 negative regulation of motor neuron apoptotic process(GO:2000672)
0.1 0.1 GO:0045896 regulation of transcription during mitosis(GO:0045896) positive regulation of transcription during mitosis(GO:0045897)
0.0 0.5 GO:0060539 diaphragm development(GO:0060539)
0.0 0.8 GO:0006465 signal peptide processing(GO:0006465)
0.0 0.2 GO:0010989 negative regulation of low-density lipoprotein particle clearance(GO:0010989)
0.0 0.2 GO:0032055 negative regulation of translation in response to stress(GO:0032055)
0.0 0.5 GO:0090503 RNA phosphodiester bond hydrolysis, exonucleolytic(GO:0090503)
0.0 0.1 GO:0042264 peptidyl-aspartic acid hydroxylation(GO:0042264)
0.0 0.4 GO:0006449 regulation of translational termination(GO:0006449)
0.0 0.6 GO:0035970 peptidyl-threonine dephosphorylation(GO:0035970)
0.0 0.3 GO:0060334 regulation of interferon-gamma-mediated signaling pathway(GO:0060334)
0.0 0.1 GO:0036092 phosphatidylinositol-3-phosphate biosynthetic process(GO:0036092)
0.0 0.7 GO:0031167 rRNA methylation(GO:0031167)
0.0 0.3 GO:0000395 mRNA 5'-splice site recognition(GO:0000395)
0.0 0.3 GO:0017196 N-terminal peptidyl-methionine acetylation(GO:0017196)
0.0 0.2 GO:0006432 phenylalanyl-tRNA aminoacylation(GO:0006432)
0.0 0.2 GO:0071985 multivesicular body sorting pathway(GO:0071985)
0.0 0.5 GO:0006120 mitochondrial electron transport, NADH to ubiquinone(GO:0006120)
0.0 0.2 GO:0090070 positive regulation of ribosome biogenesis(GO:0090070) positive regulation of rRNA processing(GO:2000234)
0.0 0.3 GO:0051934 dopamine uptake involved in synaptic transmission(GO:0051583) regulation of dopamine uptake involved in synaptic transmission(GO:0051584) catecholamine uptake involved in synaptic transmission(GO:0051934) regulation of catecholamine uptake involved in synaptic transmission(GO:0051940)
0.0 0.4 GO:0051601 exocyst localization(GO:0051601)
0.0 1.2 GO:0048791 calcium ion-regulated exocytosis of neurotransmitter(GO:0048791)
0.0 3.0 GO:1903955 positive regulation of protein targeting to mitochondrion(GO:1903955)
0.0 0.5 GO:0060670 branching involved in labyrinthine layer morphogenesis(GO:0060670)
0.0 0.9 GO:0048268 clathrin coat assembly(GO:0048268)
0.0 0.7 GO:0044364 killing of cells of other organism(GO:0031640) disruption of cells of other organism(GO:0044364)
0.0 0.1 GO:0090309 positive regulation of methylation-dependent chromatin silencing(GO:0090309)
0.0 0.3 GO:0070365 hepatocyte differentiation(GO:0070365)
0.0 0.7 GO:0045116 protein neddylation(GO:0045116)
0.0 0.8 GO:0015991 energy coupled proton transmembrane transport, against electrochemical gradient(GO:0015988) ATP hydrolysis coupled proton transport(GO:0015991)
0.0 0.3 GO:0071340 skeletal muscle acetylcholine-gated channel clustering(GO:0071340)
0.0 0.1 GO:0006667 sphinganine metabolic process(GO:0006667) regulation of lipophagy(GO:1904502) positive regulation of lipophagy(GO:1904504)
0.0 0.5 GO:0007289 spermatid nucleus differentiation(GO:0007289)
0.0 0.2 GO:0016255 attachment of GPI anchor to protein(GO:0016255)
0.0 0.1 GO:1903361 protein localization to basolateral plasma membrane(GO:1903361)
0.0 0.2 GO:0045292 mRNA cis splicing, via spliceosome(GO:0045292)
0.0 0.4 GO:0043248 proteasome assembly(GO:0043248)
0.0 0.2 GO:0018095 protein polyglutamylation(GO:0018095)
0.0 0.2 GO:0014029 neural crest formation(GO:0014029)
0.0 1.0 GO:0016601 Rac protein signal transduction(GO:0016601)
0.0 0.1 GO:0071806 protein import into peroxisome matrix(GO:0016558) intracellular protein transmembrane import(GO:0044743) intracellular protein transmembrane transport(GO:0065002) protein transmembrane transport(GO:0071806)
0.0 0.6 GO:0006903 vesicle targeting(GO:0006903)
0.0 0.2 GO:0051490 negative regulation of filopodium assembly(GO:0051490)
0.0 0.1 GO:1903722 regulation of centriole elongation(GO:1903722)
0.0 0.2 GO:0006488 dolichol-linked oligosaccharide biosynthetic process(GO:0006488)
0.0 0.1 GO:0032020 ISG15-protein conjugation(GO:0032020)
0.0 0.3 GO:0000028 ribosomal small subunit assembly(GO:0000028)
0.0 0.2 GO:0033234 negative regulation of protein sumoylation(GO:0033234)
0.0 0.3 GO:0000338 protein deneddylation(GO:0000338)
0.0 0.3 GO:1903541 regulation of exosomal secretion(GO:1903541) positive regulation of exosomal secretion(GO:1903543)
0.0 0.2 GO:0070935 3'-UTR-mediated mRNA stabilization(GO:0070935)
0.0 0.5 GO:0031146 SCF-dependent proteasomal ubiquitin-dependent protein catabolic process(GO:0031146)
0.0 0.3 GO:0015985 energy coupled proton transport, down electrochemical gradient(GO:0015985) ATP synthesis coupled proton transport(GO:0015986)
0.0 0.9 GO:0032543 mitochondrial translation(GO:0032543)
0.0 0.1 GO:2001197 regulation of basement membrane assembly involved in embryonic body morphogenesis(GO:1904259) positive regulation of basement membrane assembly involved in embryonic body morphogenesis(GO:1904261) basement membrane assembly involved in embryonic body morphogenesis(GO:2001197)
0.0 0.3 GO:0048026 positive regulation of mRNA splicing, via spliceosome(GO:0048026)
0.0 0.5 GO:0097031 NADH dehydrogenase complex assembly(GO:0010257) mitochondrial respiratory chain complex I assembly(GO:0032981) mitochondrial respiratory chain complex I biogenesis(GO:0097031)
0.0 0.5 GO:0071364 cellular response to epidermal growth factor stimulus(GO:0071364)
0.0 0.1 GO:0048793 pronephros development(GO:0048793)
0.0 0.1 GO:0006983 ER overload response(GO:0006983)
0.0 0.5 GO:0043550 regulation of lipid kinase activity(GO:0043550)
0.0 0.1 GO:0061484 hematopoietic stem cell homeostasis(GO:0061484)
0.0 0.1 GO:0045792 negative regulation of cell size(GO:0045792)
0.0 0.2 GO:0048096 chromatin-mediated maintenance of transcription(GO:0048096)
0.0 0.1 GO:0031054 pre-miRNA processing(GO:0031054)
0.0 0.3 GO:0070266 necroptotic process(GO:0070266)
0.0 0.1 GO:0035873 lactate transport(GO:0015727) lactate transmembrane transport(GO:0035873) plasma membrane lactate transport(GO:0035879)
0.0 1.7 GO:0008643 carbohydrate transport(GO:0008643)
0.0 0.3 GO:0042255 ribosome assembly(GO:0042255)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 0.9 GO:0099631 postsynaptic endocytic zone cytoplasmic component(GO:0099631)
0.3 0.9 GO:1903095 microprocessor complex(GO:0070877) ribonuclease III complex(GO:1903095)
0.3 1.2 GO:1990769 proximal neuron projection(GO:1990769)
0.3 1.9 GO:0071818 BAT3 complex(GO:0071818) ER membrane insertion complex(GO:0072379)
0.1 0.4 GO:0031090 organelle membrane(GO:0031090)
0.1 0.4 GO:0044614 nuclear pore cytoplasmic filaments(GO:0044614)
0.1 0.5 GO:0070436 Grb2-EGFR complex(GO:0070436)
0.1 0.9 GO:0005956 protein kinase CK2 complex(GO:0005956)
0.1 0.6 GO:0097441 basilar dendrite(GO:0097441)
0.1 0.5 GO:0005658 alpha DNA polymerase:primase complex(GO:0005658)
0.1 0.8 GO:0005787 signal peptidase complex(GO:0005787)
0.1 0.6 GO:0035032 phosphatidylinositol 3-kinase complex, class III(GO:0035032)
0.1 0.8 GO:0005850 eukaryotic translation initiation factor 2 complex(GO:0005850)
0.1 1.0 GO:0005885 Arp2/3 protein complex(GO:0005885)
0.1 0.2 GO:0034657 GID complex(GO:0034657)
0.1 0.3 GO:0034715 pICln-Sm protein complex(GO:0034715)
0.1 0.2 GO:0043541 UDP-N-acetylglucosamine transferase complex(GO:0043541)
0.1 0.2 GO:0031533 mRNA cap methyltransferase complex(GO:0031533)
0.1 0.3 GO:0098888 extrinsic component of presynaptic membrane(GO:0098888)
0.1 0.8 GO:0032045 guanyl-nucleotide exchange factor complex(GO:0032045)
0.1 0.5 GO:0000243 commitment complex(GO:0000243)
0.1 0.3 GO:0000125 PCAF complex(GO:0000125)
0.1 0.3 GO:0070847 core mediator complex(GO:0070847)
0.1 0.2 GO:0009328 phenylalanine-tRNA ligase complex(GO:0009328)
0.1 0.2 GO:0071797 LUBAC complex(GO:0071797)
0.0 0.9 GO:0033178 proton-transporting two-sector ATPase complex, catalytic domain(GO:0033178)
0.0 0.6 GO:0005751 mitochondrial respiratory chain complex IV(GO:0005751)
0.0 0.3 GO:0042406 extrinsic component of endoplasmic reticulum membrane(GO:0042406)
0.0 0.5 GO:0000124 SAGA complex(GO:0000124)
0.0 0.6 GO:0017101 aminoacyl-tRNA synthetase multienzyme complex(GO:0017101)
0.0 0.3 GO:0097255 R2TP complex(GO:0097255)
0.0 0.2 GO:0070876 SOSS complex(GO:0070876)
0.0 0.3 GO:0000127 transcription factor TFIIIC complex(GO:0000127)
0.0 0.8 GO:0005839 proteasome core complex(GO:0005839)
0.0 0.4 GO:0097136 Bcl-2 family protein complex(GO:0097136)
0.0 0.2 GO:0000220 vacuolar proton-transporting V-type ATPase, V0 domain(GO:0000220)
0.0 0.2 GO:0043527 tRNA methyltransferase complex(GO:0043527)
0.0 1.1 GO:0000314 organellar small ribosomal subunit(GO:0000314) mitochondrial small ribosomal subunit(GO:0005763)
0.0 2.4 GO:0022625 cytosolic large ribosomal subunit(GO:0022625)
0.0 0.1 GO:0071001 U4/U6 snRNP(GO:0071001)
0.0 0.3 GO:0033176 proton-transporting V-type ATPase complex(GO:0033176)
0.0 0.3 GO:0071541 eukaryotic translation initiation factor 3 complex, eIF3m(GO:0071541)
0.0 0.2 GO:0071203 WASH complex(GO:0071203)
0.0 0.7 GO:0005689 U12-type spliceosomal complex(GO:0005689)
0.0 0.4 GO:0005662 DNA replication factor A complex(GO:0005662)
0.0 1.8 GO:0005746 mitochondrial respiratory chain(GO:0005746)
0.0 0.2 GO:0042765 GPI-anchor transamidase complex(GO:0042765)
0.0 0.1 GO:1990415 Pex17p-Pex14p docking complex(GO:1990415) peroxisomal importomer complex(GO:1990429)
0.0 0.2 GO:0000813 ESCRT I complex(GO:0000813)
0.0 0.4 GO:0017119 Golgi transport complex(GO:0017119)
0.0 0.5 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.0 0.2 GO:0000138 Golgi trans cisterna(GO:0000138)
0.0 0.1 GO:0034388 Pwp2p-containing subcomplex of 90S preribosome(GO:0034388)
0.0 0.4 GO:0000145 exocyst(GO:0000145)
0.0 0.3 GO:0031588 nucleotide-activated protein kinase complex(GO:0031588)
0.0 0.3 GO:0005665 DNA-directed RNA polymerase II, core complex(GO:0005665)
0.0 0.5 GO:0031307 integral component of mitochondrial outer membrane(GO:0031307)
0.0 0.2 GO:0034518 mRNA cap binding complex(GO:0005845) RNA cap binding complex(GO:0034518)
0.0 0.1 GO:0017059 serine C-palmitoyltransferase complex(GO:0017059) endoplasmic reticulum palmitoyltransferase complex(GO:0031211)
0.0 0.1 GO:0031931 TORC1 complex(GO:0031931)
0.0 0.8 GO:0000502 proteasome complex(GO:0000502)
0.0 0.7 GO:0000315 organellar large ribosomal subunit(GO:0000315) mitochondrial large ribosomal subunit(GO:0005762)
0.0 0.1 GO:0032777 Piccolo NuA4 histone acetyltransferase complex(GO:0032777)
0.0 0.6 GO:0022627 cytosolic small ribosomal subunit(GO:0022627)
0.0 0.3 GO:0032040 small-subunit processome(GO:0032040)
0.0 0.3 GO:0030687 preribosome, large subunit precursor(GO:0030687)
0.0 0.1 GO:0045095 keratin filament(GO:0045095)
0.0 0.9 GO:0030864 cortical actin cytoskeleton(GO:0030864)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.7 GO:0005459 UDP-galactose transmembrane transporter activity(GO:0005459)
0.2 0.9 GO:0004525 ribonuclease III activity(GO:0004525) double-stranded RNA-specific ribonuclease activity(GO:0032296)
0.2 0.8 GO:0004792 thiosulfate sulfurtransferase activity(GO:0004792)
0.1 1.9 GO:0015643 toxic substance binding(GO:0015643)
0.1 0.4 GO:0000822 inositol hexakisphosphate binding(GO:0000822)
0.1 1.0 GO:0035368 selenocysteine insertion sequence binding(GO:0035368)
0.1 0.3 GO:0000992 polymerase III regulatory region sequence-specific DNA binding(GO:0000992) RNA polymerase III type 1 promoter sequence-specific DNA binding(GO:0001002) RNA polymerase III type 2 promoter sequence-specific DNA binding(GO:0001003)
0.1 0.9 GO:0032050 clathrin heavy chain binding(GO:0032050)
0.1 0.6 GO:0000774 adenyl-nucleotide exchange factor activity(GO:0000774)
0.1 0.6 GO:1990446 U1 snRNP binding(GO:1990446)
0.1 0.2 GO:0001042 RNA polymerase I core binding(GO:0001042)
0.1 0.2 GO:0004482 mRNA (guanine-N7-)-methyltransferase activity(GO:0004482)
0.1 0.2 GO:0004814 arginine-tRNA ligase activity(GO:0004814) arginine binding(GO:0034618)
0.1 0.8 GO:0031386 protein tag(GO:0031386)
0.1 0.2 GO:0070740 tubulin-glutamic acid ligase activity(GO:0070740)
0.1 1.1 GO:0004129 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.1 0.7 GO:0097371 MDM2/MDM4 family protein binding(GO:0097371)
0.0 0.6 GO:0008553 hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553)
0.0 0.5 GO:0005168 neurotrophin TRKA receptor binding(GO:0005168)
0.0 0.7 GO:0008649 rRNA methyltransferase activity(GO:0008649)
0.0 0.4 GO:0071253 connexin binding(GO:0071253)
0.0 0.4 GO:0051434 BH3 domain binding(GO:0051434)
0.0 0.2 GO:0043141 ATP-dependent 5'-3' DNA helicase activity(GO:0043141)
0.0 0.2 GO:0036435 K48-linked polyubiquitin binding(GO:0036435)
0.0 0.5 GO:0015197 peptide transporter activity(GO:0015197)
0.0 0.8 GO:0004298 threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
0.0 0.3 GO:0019788 NEDD8 transferase activity(GO:0019788)
0.0 0.2 GO:0034235 GPI anchor binding(GO:0034235)
0.0 0.4 GO:0047372 acylglycerol lipase activity(GO:0047372)
0.0 0.3 GO:0004679 AMP-activated protein kinase activity(GO:0004679)
0.0 0.4 GO:0034450 ubiquitin-ubiquitin ligase activity(GO:0034450)
0.0 0.2 GO:0004826 phenylalanine-tRNA ligase activity(GO:0004826)
0.0 0.2 GO:0046790 virion binding(GO:0046790)
0.0 0.3 GO:0030306 ADP-ribosylation factor binding(GO:0030306)
0.0 0.1 GO:0004758 serine C-palmitoyltransferase activity(GO:0004758) C-palmitoyltransferase activity(GO:0016454)
0.0 1.2 GO:0001786 phosphatidylserine binding(GO:0001786) calcium-dependent phospholipid binding(GO:0005544)
0.0 0.3 GO:0004596 peptide alpha-N-acetyltransferase activity(GO:0004596)
0.0 0.3 GO:0035615 clathrin adaptor activity(GO:0035615) endocytic adaptor activity(GO:0098748)
0.0 0.1 GO:0034739 histone deacetylase activity (H4-K16 specific)(GO:0034739)
0.0 1.8 GO:0004722 protein serine/threonine phosphatase activity(GO:0004722)
0.0 0.5 GO:0004535 poly(A)-specific ribonuclease activity(GO:0004535)
0.0 0.2 GO:0035251 UDP-glucosyltransferase activity(GO:0035251)
0.0 0.1 GO:0042296 ISG15 transferase activity(GO:0042296)
0.0 0.4 GO:0004033 aldo-keto reductase (NADP) activity(GO:0004033)
0.0 1.0 GO:0003899 DNA-directed RNA polymerase activity(GO:0003899)
0.0 0.3 GO:0046933 proton-transporting ATP synthase activity, rotational mechanism(GO:0046933)
0.0 0.1 GO:0071532 ankyrin repeat binding(GO:0071532)
0.0 0.5 GO:0003746 translation elongation factor activity(GO:0003746)
0.0 0.2 GO:0000340 RNA 7-methylguanosine cap binding(GO:0000340)
0.0 1.2 GO:0043022 ribosome binding(GO:0043022)
0.0 3.6 GO:0003735 structural constituent of ribosome(GO:0003735)
0.0 0.2 GO:0044769 ATPase activity, coupled to transmembrane movement of ions, rotational mechanism(GO:0044769)
0.0 0.1 GO:0016748 succinyltransferase activity(GO:0016748)
0.0 0.7 GO:0016922 ligand-dependent nuclear receptor binding(GO:0016922)
0.0 0.8 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.0 0.3 GO:0048407 platelet-derived growth factor binding(GO:0048407)
0.0 0.2 GO:0070742 pre-mRNA 3'-splice site binding(GO:0030628) C2H2 zinc finger domain binding(GO:0070742)
0.0 0.1 GO:0015129 lactate transmembrane transporter activity(GO:0015129)
0.0 0.1 GO:0003886 DNA (cytosine-5-)-methyltransferase activity(GO:0003886)
0.0 0.8 GO:0003743 translation initiation factor activity(GO:0003743)
0.0 0.1 GO:0070699 type II activin receptor binding(GO:0070699)
0.0 1.0 GO:0043021 ribonucleoprotein complex binding(GO:0043021)
0.0 0.5 GO:0061631 ubiquitin conjugating enzyme activity(GO:0061631)
0.0 0.6 GO:0005484 SNAP receptor activity(GO:0005484)
0.0 0.1 GO:0009019 tRNA (guanine-N1-)-methyltransferase activity(GO:0009019)
0.0 0.1 GO:0036402 proteasome-activating ATPase activity(GO:0036402)
0.0 0.3 GO:0050136 NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.0 0.3 GO:0030331 estrogen receptor binding(GO:0030331)
0.0 0.2 GO:0034236 protein kinase A catalytic subunit binding(GO:0034236)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 1.4 PID_IL8_CXCR2_PATHWAY IL8- and CXCR2-mediated signaling events
0.0 0.9 PID_ARF_3PATHWAY Arf1 pathway
0.0 0.9 PID_DNA_PK_PATHWAY DNA-PK pathway in nonhomologous end joining
0.0 0.5 PID_IL5_PATHWAY IL5-mediated signaling events
0.0 0.4 PID_ERB_GENOMIC_PATHWAY Validated nuclear estrogen receptor beta network
0.0 0.5 SIG_REGULATION_OF_THE_ACTIN_CYTOSKELETON_BY_RHO_GTPASES Genes related to regulation of the actin cytoskeleton
0.0 0.7 PID_ERBB1_INTERNALIZATION_PATHWAY Internalization of ErbB1
0.0 0.4 PID_MYC_PATHWAY C-MYC pathway
0.0 1.6 PID_P53_DOWNSTREAM_PATHWAY Direct p53 effectors

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.1 REACTOME_INHIBITION_OF_REPLICATION_INITIATION_OF_DAMAGED_DNA_BY_RB1_E2F1 Genes involved in Inhibition of replication initiation of damaged DNA by RB1/E2F1
0.1 0.8 REACTOME_MEMBRANE_BINDING_AND_TARGETTING_OF_GAG_PROTEINS Genes involved in Membrane binding and targetting of GAG proteins
0.1 0.5 REACTOME_APOBEC3G_MEDIATED_RESISTANCE_TO_HIV1_INFECTION Genes involved in APOBEC3G mediated resistance to HIV-1 infection
0.1 0.8 REACTOME_SYNTHESIS_SECRETION_AND_INACTIVATION_OF_GIP Genes involved in Synthesis, Secretion, and Inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)
0.1 1.3 REACTOME_MICRORNA_MIRNA_BIOGENESIS Genes involved in MicroRNA (miRNA) Biogenesis
0.1 1.8 REACTOME_MRNA_SPLICING_MINOR_PATHWAY Genes involved in mRNA Splicing - Minor Pathway
0.1 1.1 REACTOME_INSULIN_RECEPTOR_RECYCLING Genes involved in Insulin receptor recycling
0.1 2.0 REACTOME_EGFR_DOWNREGULATION Genes involved in EGFR downregulation
0.0 0.2 REACTOME_PHOSPHORYLATION_OF_CD3_AND_TCR_ZETA_CHAINS Genes involved in Phosphorylation of CD3 and TCR zeta chains
0.0 1.7 REACTOME_TRANSPORT_OF_VITAMINS_NUCLEOSIDES_AND_RELATED_MOLECULES Genes involved in Transport of vitamins, nucleosides, and related molecules
0.0 0.5 REACTOME_FORMATION_OF_THE_TERNARY_COMPLEX_AND_SUBSEQUENTLY_THE_43S_COMPLEX Genes involved in Formation of the ternary complex, and subsequently, the 43S complex
0.0 0.8 REACTOME_THE_ROLE_OF_NEF_IN_HIV1_REPLICATION_AND_DISEASE_PATHOGENESIS Genes involved in The role of Nef in HIV-1 replication and disease pathogenesis
0.0 1.8 REACTOME_ER_PHAGOSOME_PATHWAY Genes involved in ER-Phagosome pathway
0.0 0.8 REACTOME_CYTOSOLIC_TRNA_AMINOACYLATION Genes involved in Cytosolic tRNA aminoacylation
0.0 1.9 REACTOME_RESPIRATORY_ELECTRON_TRANSPORT Genes involved in Respiratory electron transport
0.0 2.9 REACTOME_PEPTIDE_CHAIN_ELONGATION Genes involved in Peptide chain elongation
0.0 0.3 REACTOME_REGULATION_OF_RHEB_GTPASE_ACTIVITY_BY_AMPK Genes involved in Regulation of Rheb GTPase activity by AMPK
0.0 0.2 REACTOME_CALNEXIN_CALRETICULIN_CYCLE Genes involved in Calnexin/calreticulin cycle
0.0 0.9 REACTOME_SIGNAL_TRANSDUCTION_BY_L1 Genes involved in Signal transduction by L1
0.0 0.8 REACTOME_ASSOCIATION_OF_TRIC_CCT_WITH_TARGET_PROTEINS_DURING_BIOSYNTHESIS Genes involved in Association of TriC/CCT with target proteins during biosynthesis
0.0 0.4 REACTOME_INSULIN_SYNTHESIS_AND_PROCESSING Genes involved in Insulin Synthesis and Processing
0.0 0.3 REACTOME_FORMATION_OF_ATP_BY_CHEMIOSMOTIC_COUPLING Genes involved in Formation of ATP by chemiosmotic coupling
0.0 0.3 REACTOME_SIGNALING_BY_CONSTITUTIVELY_ACTIVE_EGFR Genes involved in Signaling by constitutively active EGFR
0.0 1.6 REACTOME_REGULATION_OF_INSULIN_SECRETION Genes involved in Regulation of Insulin Secretion
0.0 0.2 REACTOME_SYNTHESIS_OF_PIPS_AT_THE_EARLY_ENDOSOME_MEMBRANE Genes involved in Synthesis of PIPs at the early endosome membrane
0.0 0.2 REACTOME_ENDOSOMAL_SORTING_COMPLEX_REQUIRED_FOR_TRANSPORT_ESCRT Genes involved in Endosomal Sorting Complex Required For Transport (ESCRT)
0.0 0.8 REACTOME_METABOLISM_OF_VITAMINS_AND_COFACTORS Genes involved in Metabolism of vitamins and cofactors
0.0 0.2 REACTOME_PURINE_SALVAGE Genes involved in Purine salvage
0.0 0.3 REACTOME_NONSENSE_MEDIATED_DECAY_ENHANCED_BY_THE_EXON_JUNCTION_COMPLEX Genes involved in Nonsense Mediated Decay Enhanced by the Exon Junction Complex
0.0 0.1 REACTOME_BILE_SALT_AND_ORGANIC_ANION_SLC_TRANSPORTERS Genes involved in Bile salt and organic anion SLC transporters
0.0 0.1 REACTOME_ANTIGEN_PRESENTATION_FOLDING_ASSEMBLY_AND_PEPTIDE_LOADING_OF_CLASS_I_MHC Genes involved in Antigen Presentation: Folding, assembly and peptide loading of class I MHC
0.0 0.3 REACTOME_RNA_POL_II_TRANSCRIPTION_PRE_INITIATION_AND_PROMOTER_OPENING Genes involved in RNA Polymerase II Transcription Pre-Initiation And Promoter Opening
0.0 0.1 REACTOME_CTNNB1_PHOSPHORYLATION_CASCADE Genes involved in Beta-catenin phosphorylation cascade
0.0 0.3 REACTOME_EXTENSION_OF_TELOMERES Genes involved in Extension of Telomeres
0.0 0.3 REACTOME_SEMA4D_INDUCED_CELL_MIGRATION_AND_GROWTH_CONE_COLLAPSE Genes involved in Sema4D induced cell migration and growth-cone collapse