Motif ID: Figla

Z-value: 0.755


Transcription factors associated with Figla:

Gene SymbolEntrez IDGene Name
Figla ENSMUSG00000030001.3 Figla



Activity profile for motif Figla.

activity profile for motif Figla


Sorted Z-values histogram for motif Figla

Sorted Z-values for motif Figla



Network of associatons between targets according to the STRING database.



First level regulatory network of Figla

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr10_+_26229707 6.935 ENSMUST00000060716.5
ENSMUST00000164660.1
Samd3

sterile alpha motif domain containing 3

chr2_+_164769892 6.529 ENSMUST00000088248.6
ENSMUST00000001439.6
Ube2c

ubiquitin-conjugating enzyme E2C

chr15_-_78773452 5.938 ENSMUST00000018313.5
Mfng
MFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase
chr11_+_99864476 5.279 ENSMUST00000092694.3
Gm11559
predicted gene 11559
chr1_+_74791516 4.757 ENSMUST00000006718.8
Wnt10a
wingless related MMTV integration site 10a
chr1_-_119053339 4.718 ENSMUST00000161301.1
ENSMUST00000161451.1
ENSMUST00000162607.1
Gli2


GLI-Kruppel family member GLI2


chr5_+_123749696 4.181 ENSMUST00000031366.7
Kntc1
kinetochore associated 1
chr13_-_100786402 3.795 ENSMUST00000174038.1
ENSMUST00000091295.7
ENSMUST00000072119.8
Ccnb1


cyclin B1


chr8_+_127064107 3.355 ENSMUST00000162536.1
ENSMUST00000026921.6
ENSMUST00000162665.1
ENSMUST00000160766.1
ENSMUST00000162602.1
ENSMUST00000162531.1
ENSMUST00000160581.1
ENSMUST00000161355.1
ENSMUST00000159537.1
Pard3








par-3 (partitioning defective 3) homolog (C. elegans)








chr6_+_47244359 3.242 ENSMUST00000060839.6
Cntnap2
contactin associated protein-like 2
chr12_+_109459843 3.134 ENSMUST00000173812.1
Dlk1
delta-like 1 homolog (Drosophila)
chrX_-_23266751 3.077 ENSMUST00000115316.2
Klhl13
kelch-like 13
chr15_+_25622525 3.041 ENSMUST00000110457.1
ENSMUST00000137601.1
Myo10

myosin X

chr17_-_35700520 2.874 ENSMUST00000119825.1
Ddr1
discoidin domain receptor family, member 1
chr7_-_127218390 2.824 ENSMUST00000142356.1
ENSMUST00000106314.1
Sept1

septin 1

chr9_+_91368970 2.781 ENSMUST00000172646.1
Zic4
zinc finger protein of the cerebellum 4
chr4_+_11156411 2.741 ENSMUST00000029865.3
Trp53inp1
transformation related protein 53 inducible nuclear protein 1
chr6_+_105677745 2.623 ENSMUST00000113261.2
ENSMUST00000113264.2
Cntn4

contactin 4

chr7_-_127218303 2.494 ENSMUST00000106313.1
Sept1
septin 1
chr2_-_62483637 2.435 ENSMUST00000136686.1
ENSMUST00000102733.3
Gcg

glucagon

chr9_+_91368811 2.428 ENSMUST00000173054.1
Zic4
zinc finger protein of the cerebellum 4
chr2_+_168081004 2.375 ENSMUST00000052125.6
Pard6b
par-6 (partitioning defective 6) homolog beta (C. elegans)
chr7_-_144939823 2.373 ENSMUST00000093962.4
Ccnd1
cyclin D1
chr2_+_92915080 2.263 ENSMUST00000028648.2
Syt13
synaptotagmin XIII
chr11_+_43528759 2.256 ENSMUST00000050574.6
Ccnjl
cyclin J-like
chr4_+_128883549 2.215 ENSMUST00000035667.8
Trim62
tripartite motif-containing 62
chr4_-_83324239 2.146 ENSMUST00000048274.4
ENSMUST00000102823.3
Ttc39b

tetratricopeptide repeat domain 39B

chr2_+_102659213 2.133 ENSMUST00000111213.1
Slc1a2
solute carrier family 1 (glial high affinity glutamate transporter), member 2
chr16_-_46010212 2.119 ENSMUST00000130481.1
Plcxd2
phosphatidylinositol-specific phospholipase C, X domain containing 2
chr12_-_34528844 2.077 ENSMUST00000110819.2
Hdac9
histone deacetylase 9
chr14_-_104467984 2.067 ENSMUST00000053016.8
Pou4f1
POU domain, class 4, transcription factor 1
chr6_-_3494587 1.998 ENSMUST00000049985.8
Hepacam2
HEPACAM family member 2
chr15_-_10714612 1.856 ENSMUST00000169385.1
Rai14
retinoic acid induced 14
chr9_-_96437434 1.833 ENSMUST00000070500.2
BC043934
cDNA sequence BC043934
chr3_+_107036156 1.824 ENSMUST00000052718.3
Kcna3
potassium voltage-gated channel, shaker-related subfamily, member 3
chr9_+_74848437 1.816 ENSMUST00000161862.1
ENSMUST00000162089.1
ENSMUST00000160017.1
ENSMUST00000160950.1
Gm16551


Gm20649
predicted gene 16551


predicted gene 20649
chr2_+_20519776 1.798 ENSMUST00000114604.2
ENSMUST00000066509.3
Etl4

enhancer trap locus 4

chr2_+_19909769 1.679 ENSMUST00000114610.1
Etl4
enhancer trap locus 4
chr19_-_5796924 1.657 ENSMUST00000174808.1
Malat1
metastasis associated lung adenocarcinoma transcript 1 (non-coding RNA)
chr12_-_91779129 1.647 ENSMUST00000170077.1
Ston2
stonin 2
chr19_-_5797410 1.553 ENSMUST00000173314.1
Malat1
metastasis associated lung adenocarcinoma transcript 1 (non-coding RNA)
chr16_-_16560046 1.541 ENSMUST00000172181.2
Fgd4
FYVE, RhoGEF and PH domain containing 4
chr3_+_31095052 1.508 ENSMUST00000118470.1
ENSMUST00000029194.5
ENSMUST00000123532.1
ENSMUST00000117728.1
Skil



SKI-like



chr2_-_153529941 1.466 ENSMUST00000035346.7
8430427H17Rik
RIKEN cDNA 8430427H17 gene
chr5_-_28210022 1.456 ENSMUST00000118882.1
Cnpy1
canopy 1 homolog (zebrafish)
chr1_-_183147461 1.451 ENSMUST00000171366.1
Disp1
dispatched homolog 1 (Drosophila)
chr14_-_20181773 1.406 ENSMUST00000024011.8
Kcnk5
potassium channel, subfamily K, member 5
chr11_-_68927049 1.404 ENSMUST00000038932.7
Odf4
outer dense fiber of sperm tails 4
chr9_-_73968901 1.377 ENSMUST00000184666.1
Unc13c
unc-13 homolog C (C. elegans)
chr8_+_72135247 1.373 ENSMUST00000003575.9
Tpm4
tropomyosin 4
chr9_+_87022014 1.356 ENSMUST00000168529.2
ENSMUST00000174724.1
ENSMUST00000173126.1
Cyb5r4


cytochrome b5 reductase 4


chr9_-_44342332 1.338 ENSMUST00000097558.3
Hmbs
hydroxymethylbilane synthase
chr16_-_16560201 1.323 ENSMUST00000162045.1
ENSMUST00000162124.1
ENSMUST00000161861.1
Fgd4


FYVE, RhoGEF and PH domain containing 4


chr8_+_105305572 1.281 ENSMUST00000109375.2
Elmo3
engulfment and cell motility 3
chr7_+_19094594 1.260 ENSMUST00000049454.5
Six5
sine oculis-related homeobox 5
chr15_+_99717515 1.258 ENSMUST00000023760.6
ENSMUST00000162194.1
Gpd1

glycerol-3-phosphate dehydrogenase 1 (soluble)

chr8_+_95352258 1.240 ENSMUST00000034243.5
Mmp15
matrix metallopeptidase 15
chr1_+_92831614 1.232 ENSMUST00000045970.6
Gpc1
glypican 1
chr17_-_47924400 1.222 ENSMUST00000113263.1
ENSMUST00000097311.2
Foxp4

forkhead box P4

chr4_+_107968332 1.192 ENSMUST00000106713.3
Slc1a7
solute carrier family 1 (glutamate transporter), member 7
chr7_-_30973464 1.181 ENSMUST00000001279.8
Lsr
lipolysis stimulated lipoprotein receptor
chr11_+_101316917 1.176 ENSMUST00000151385.1
Psme3
proteaseome (prosome, macropain) activator subunit 3 (PA28 gamma, Ki)
chr9_+_102720287 1.171 ENSMUST00000130602.1
Amotl2
angiomotin-like 2
chr5_-_36988922 1.147 ENSMUST00000166339.1
ENSMUST00000043964.6
Wfs1

Wolfram syndrome 1 homolog (human)

chr5_+_146231211 1.143 ENSMUST00000161181.1
ENSMUST00000161652.1
ENSMUST00000031640.8
ENSMUST00000159467.1
Cdk8



cyclin-dependent kinase 8



chr3_+_95588960 1.138 ENSMUST00000176674.1
ENSMUST00000177389.1
ENSMUST00000176755.1
Golph3l


golgi phosphoprotein 3-like


chr9_-_42124276 1.086 ENSMUST00000060989.8
Sorl1
sortilin-related receptor, LDLR class A repeats-containing
chr2_-_154569720 1.084 ENSMUST00000000894.5
E2f1
E2F transcription factor 1
chr4_+_121039385 1.070 ENSMUST00000030372.5
Col9a2
collagen, type IX, alpha 2
chr3_+_95588928 1.070 ENSMUST00000177390.1
ENSMUST00000098861.4
ENSMUST00000060323.5
Golph3l


golgi phosphoprotein 3-like


chr4_-_135494615 1.019 ENSMUST00000102549.3
Nipal3
NIPA-like domain containing 3
chr2_+_20737306 1.008 ENSMUST00000114606.1
ENSMUST00000114608.1
Etl4

enhancer trap locus 4

chr3_+_95588990 0.998 ENSMUST00000177399.1
Golph3l
golgi phosphoprotein 3-like
chr3_+_90537306 0.996 ENSMUST00000107335.1
S100a16
S100 calcium binding protein A16
chr3_+_90537242 0.984 ENSMUST00000098911.3
S100a16
S100 calcium binding protein A16
chr9_-_57836706 0.975 ENSMUST00000164010.1
ENSMUST00000171444.1
ENSMUST00000098686.3
Arid3b


AT rich interactive domain 3B (BRIGHT-like)


chr17_+_47630690 0.968 ENSMUST00000024779.8
Usp49
ubiquitin specific peptidase 49
chr8_+_13757663 0.963 ENSMUST00000043962.8
Cdc16
CDC16 cell division cycle 16
chr14_+_27039001 0.957 ENSMUST00000035336.3
Il17rd
interleukin 17 receptor D
chr10_+_79974409 0.956 ENSMUST00000131816.1
Grin3b
glutamate receptor, ionotropic, NMDA3B
chr11_+_115824029 0.955 ENSMUST00000103032.4
ENSMUST00000133250.1
ENSMUST00000177736.1
Llgl2


lethal giant larvae homolog 2 (Drosophila)


chrX_+_151522352 0.951 ENSMUST00000148622.1
Phf8
PHD finger protein 8
chr4_-_42168603 0.942 ENSMUST00000098121.3
Gm13305
predicted gene 13305
chr11_-_82871133 0.923 ENSMUST00000071152.7
ENSMUST00000108173.3
Rffl

ring finger and FYVE like domain containing protein

chr5_+_137629169 0.921 ENSMUST00000176667.1
Lrch4
leucine-rich repeats and calponin homology (CH) domain containing 4
chr11_+_101316200 0.916 ENSMUST00000142640.1
ENSMUST00000019470.7
Psme3

proteaseome (prosome, macropain) activator subunit 3 (PA28 gamma, Ki)

chr8_-_111393810 0.878 ENSMUST00000038475.8
Fa2h
fatty acid 2-hydroxylase
chr11_-_100770926 0.873 ENSMUST00000139341.1
ENSMUST00000017891.7
Ghdc

GH3 domain containing

chr8_-_4217133 0.870 ENSMUST00000175906.1
BC068157
cDNA sequence BC068157
chr9_+_106453838 0.870 ENSMUST00000024260.6
Pcbp4
poly(rC) binding protein 4
chr19_+_5740885 0.849 ENSMUST00000081496.5
Ltbp3
latent transforming growth factor beta binding protein 3
chr6_-_40436104 0.848 ENSMUST00000039008.6
ENSMUST00000101492.3
E330009J07Rik

RIKEN cDNA E330009J07 gene

chr4_-_11386757 0.833 ENSMUST00000108313.1
ENSMUST00000108311.2
Esrp1

epithelial splicing regulatory protein 1

chr7_+_141216626 0.805 ENSMUST00000141804.1
ENSMUST00000148975.1
Rassf7

Ras association (RalGDS/AF-6) domain family (N-terminal) member 7

chr16_+_43889936 0.801 ENSMUST00000151183.1
2610015P09Rik
RIKEN cDNA 2610015P09 gene
chr16_-_20730544 0.800 ENSMUST00000076422.5
Thpo
thrombopoietin
chr8_-_4217261 0.785 ENSMUST00000168386.2
BC068157
cDNA sequence BC068157
chr11_+_32205483 0.771 ENSMUST00000121182.1
Snrnp25
small nuclear ribonucleoprotein 25 (U11/U12)
chr7_+_45639964 0.761 ENSMUST00000148532.1
Mamstr
MEF2 activating motif and SAP domain containing transcriptional regulator
chr11_-_77513335 0.757 ENSMUST00000060417.4
Trp53i13
transformation related protein 53 inducible protein 13
chr16_+_43889896 0.754 ENSMUST00000122014.1
ENSMUST00000178400.1
2610015P09Rik

RIKEN cDNA 2610015P09 gene

chr2_-_58357752 0.742 ENSMUST00000112608.2
ENSMUST00000112607.2
ENSMUST00000028178.7
Acvr1c


activin A receptor, type IC


chr4_+_15881255 0.739 ENSMUST00000029876.1
Calb1
calbindin 1
chr11_-_54962903 0.736 ENSMUST00000108885.1
ENSMUST00000102730.2
ENSMUST00000018482.6
ENSMUST00000108886.1
ENSMUST00000102731.1
Tnip1




TNFAIP3 interacting protein 1




chr7_+_28180226 0.719 ENSMUST00000172467.1
Dyrk1b
dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1b
chr9_+_102718424 0.712 ENSMUST00000156485.1
ENSMUST00000145937.1
ENSMUST00000134483.1
Amotl2


angiomotin-like 2


chr4_-_133756769 0.711 ENSMUST00000008024.6
Arid1a
AT rich interactive domain 1A (SWI-like)
chr1_+_129273344 0.711 ENSMUST00000073527.6
ENSMUST00000040311.7
Thsd7b

thrombospondin, type I, domain containing 7B

chr3_+_9250602 0.681 ENSMUST00000155203.1
Zbtb10
zinc finger and BTB domain containing 10
chr5_-_74702891 0.671 ENSMUST00000117388.1
Lnx1
ligand of numb-protein X 1
chr10_-_117710745 0.665 ENSMUST00000020408.8
ENSMUST00000105263.1
Mdm2

transformed mouse 3T3 cell double minute 2

chr5_-_73191848 0.652 ENSMUST00000176910.1
Fryl
furry homolog-like (Drosophila)
chr4_+_116557658 0.637 ENSMUST00000030460.8
Gpbp1l1
GC-rich promoter binding protein 1-like 1
chr7_-_131410325 0.634 ENSMUST00000154602.1
Ikzf5
IKAROS family zinc finger 5
chr16_+_43889800 0.633 ENSMUST00000132859.1
2610015P09Rik
RIKEN cDNA 2610015P09 gene
chr17_+_34039437 0.626 ENSMUST00000131134.1
ENSMUST00000087497.4
ENSMUST00000114255.1
ENSMUST00000114252.1
Col11a2



collagen, type XI, alpha 2



chr10_-_62726086 0.619 ENSMUST00000133371.1
Stox1
storkhead box 1
chr4_-_20778527 0.618 ENSMUST00000119374.1
Nkain3
Na+/K+ transporting ATPase interacting 3
chrX_-_53370470 0.614 ENSMUST00000096447.2
ENSMUST00000023836.3
Mospd1

motile sperm domain containing 1

chr2_+_49619277 0.580 ENSMUST00000028102.7
Kif5c
kinesin family member 5C
chr1_-_153332724 0.576 ENSMUST00000027752.8
Lamc1
laminin, gamma 1
chr1_-_128102412 0.555 ENSMUST00000112538.1
ENSMUST00000086614.5
Zranb3

zinc finger, RAN-binding domain containing 3

chr7_+_28180272 0.530 ENSMUST00000173223.1
Dyrk1b
dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1b
chr6_+_3993776 0.527 ENSMUST00000031673.5
Gngt1
guanine nucleotide binding protein (G protein), gamma transducing activity polypeptide 1
chr17_+_73107982 0.526 ENSMUST00000130574.1
ENSMUST00000149064.1
ENSMUST00000067545.6
Lclat1


lysocardiolipin acyltransferase 1


chr5_+_91517615 0.524 ENSMUST00000040576.9
Parm1
prostate androgen-regulated mucin-like protein 1
chr9_-_20898592 0.523 ENSMUST00000004206.8
Eif3g
eukaryotic translation initiation factor 3, subunit G
chr4_-_135494499 0.519 ENSMUST00000105856.2
Nipal3
NIPA-like domain containing 3
chr2_-_170406501 0.505 ENSMUST00000154650.1
Bcas1
breast carcinoma amplified sequence 1
chr10_-_127030813 0.505 ENSMUST00000040560.4
Tsfm
Ts translation elongation factor, mitochondrial
chr11_+_32205411 0.502 ENSMUST00000039601.3
ENSMUST00000149043.1
Snrnp25

small nuclear ribonucleoprotein 25 (U11/U12)

chr2_+_31759993 0.495 ENSMUST00000124089.1
Abl1
c-abl oncogene 1, non-receptor tyrosine kinase
chr2_-_73580288 0.489 ENSMUST00000028515.3
Chrna1
cholinergic receptor, nicotinic, alpha polypeptide 1 (muscle)
chr5_-_28210168 0.483 ENSMUST00000117098.1
Cnpy1
canopy 1 homolog (zebrafish)
chr7_+_121707189 0.481 ENSMUST00000065310.2
1700069B07Rik
RIKEN cDNA 1700069B07 gene
chr1_+_92906959 0.474 ENSMUST00000060913.6
Dusp28
dual specificity phosphatase 28
chr8_-_47352348 0.469 ENSMUST00000110367.2
Stox2
storkhead box 2
chr10_+_36974536 0.462 ENSMUST00000019911.7
Hdac2
histone deacetylase 2
chr8_-_4216912 0.460 ENSMUST00000177491.1
BC068157
cDNA sequence BC068157
chr4_+_132274385 0.453 ENSMUST00000105963.1
Taf12
TAF12 RNA polymerase II, TATA box binding protein (TBP)-associated factor
chr6_+_54264839 0.441 ENSMUST00000146114.1
Chn2
chimerin (chimaerin) 2
chr9_-_102626095 0.435 ENSMUST00000093791.3
Cep63
centrosomal protein 63
chrX_+_112604274 0.433 ENSMUST00000071814.6
Zfp711
zinc finger protein 711
chr12_+_55155104 0.421 ENSMUST00000110708.2
Srp54b
signal recognition particle 54B
chr11_+_117809653 0.419 ENSMUST00000026649.7
ENSMUST00000177131.1
ENSMUST00000132298.1
Syngr2

Gm20708
synaptogyrin 2

predicted gene 20708
chr7_-_131410495 0.411 ENSMUST00000121033.1
ENSMUST00000046306.8
Ikzf5

IKAROS family zinc finger 5

chr2_+_27079371 0.405 ENSMUST00000091233.6
Adamtsl2
ADAMTS-like 2
chr5_+_150756295 0.405 ENSMUST00000110486.1
Pds5b
PDS5, regulator of cohesion maintenance, homolog B (S. cerevisiae)
chr4_+_132274369 0.393 ENSMUST00000030731.4
Taf12
TAF12 RNA polymerase II, TATA box binding protein (TBP)-associated factor
chr15_+_88819584 0.392 ENSMUST00000024042.3
Creld2
cysteine-rich with EGF-like domains 2
chr11_-_48946148 0.382 ENSMUST00000104958.1
Psme2b
protease (prosome, macropain) activator subunit 2B
chr11_-_107915041 0.375 ENSMUST00000039071.2
Cacng5
calcium channel, voltage-dependent, gamma subunit 5
chr5_+_122209729 0.372 ENSMUST00000072602.7
ENSMUST00000143560.1
Hvcn1

hydrogen voltage-gated channel 1

chr17_+_24473884 0.370 ENSMUST00000054946.3
ENSMUST00000164508.1
Bricd5

BRICHOS domain containing 5

chr5_+_147077346 0.364 ENSMUST00000110557.1
Polr1d
polymerase (RNA) I polypeptide D
chr8_-_4217459 0.364 ENSMUST00000176227.1
BC068157
cDNA sequence BC068157
chr7_+_35119285 0.360 ENSMUST00000042985.9
Cebpa
CCAAT/enhancer binding protein (C/EBP), alpha
chr11_-_97280470 0.360 ENSMUST00000167806.1
ENSMUST00000172108.1
Npepps

aminopeptidase puromycin sensitive

chr9_+_57560934 0.358 ENSMUST00000045791.9
Scamp2
secretory carrier membrane protein 2
chr18_-_51865881 0.350 ENSMUST00000091905.2
Gm4950
predicted pseudogene 4950
chr11_-_83645621 0.347 ENSMUST00000182502.1
Rpl9-ps1
ribosomal protein L9, pseudogene 1
chr12_-_55080098 0.346 ENSMUST00000021406.5
2700097O09Rik
RIKEN cDNA 2700097O09 gene
chr11_-_97280432 0.319 ENSMUST00000165216.1
Npepps
aminopeptidase puromycin sensitive
chr17_+_28858411 0.312 ENSMUST00000114737.1
ENSMUST00000056866.5
Pnpla1

patatin-like phospholipase domain containing 1

chr18_-_73815392 0.311 ENSMUST00000025439.3
Me2
malic enzyme 2, NAD(+)-dependent, mitochondrial
chr10_-_127030789 0.305 ENSMUST00000120547.1
ENSMUST00000152054.1
Tsfm

Ts translation elongation factor, mitochondrial

chr7_+_44896077 0.298 ENSMUST00000071207.7
ENSMUST00000166849.1
ENSMUST00000168712.1
ENSMUST00000168389.1
Fuz



fuzzy homolog (Drosophila)



chr8_-_47289394 0.287 ENSMUST00000079195.5
Stox2
storkhead box 2
chr4_+_116558056 0.282 ENSMUST00000106475.1
Gpbp1l1
GC-rich promoter binding protein 1-like 1
chrX_-_74368547 0.281 ENSMUST00000155676.1
Ubl4
ubiquitin-like 4
chrX_+_48108912 0.271 ENSMUST00000114998.1
ENSMUST00000115000.3
Xpnpep2

X-prolyl aminopeptidase (aminopeptidase P) 2, membrane-bound

chr16_+_32271468 0.255 ENSMUST00000093183.3
Smco1
single-pass membrane protein with coiled-coil domains 1
chr18_-_80469664 0.252 ENSMUST00000036229.6
Ctdp1
CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) phosphatase, subunit 1
chr2_+_14873656 0.247 ENSMUST00000114718.1
ENSMUST00000114719.1
Cacnb2

calcium channel, voltage-dependent, beta 2 subunit

chr4_+_108619925 0.246 ENSMUST00000030320.6
Cc2d1b
coiled-coil and C2 domain containing 1B
chr5_-_30907692 0.231 ENSMUST00000132034.2
ENSMUST00000132253.2
Ost4

oligosaccharyltransferase 4 homolog (S. cerevisiae)

chr11_+_71749914 0.217 ENSMUST00000150531.1
Wscd1
WSC domain containing 1
chr11_-_100146120 0.212 ENSMUST00000007317.7
Krt19
keratin 19
chr6_-_53820764 0.210 ENSMUST00000127748.2
Tril
TLR4 interactor with leucine-rich repeats
chr14_+_105258712 0.205 ENSMUST00000138283.1
Ndfip2
Nedd4 family interacting protein 2
chr6_+_29694204 0.204 ENSMUST00000046750.7
ENSMUST00000115250.3
Tspan33

tetraspanin 33

chr16_+_17451981 0.202 ENSMUST00000006293.3
Crkl
v-crk sarcoma virus CT10 oncogene homolog (avian)-like
chrX_-_104671048 0.194 ENSMUST00000042070.5
Zdhhc15
zinc finger, DHHC domain containing 15
chr15_-_81729864 0.193 ENSMUST00000171115.1
ENSMUST00000170134.1
ENSMUST00000052374.5
Rangap1


RAN GTPase activating protein 1


chr8_+_46163733 0.190 ENSMUST00000110376.1
4933411K20Rik
RIKEN cDNA 4933411K20 gene
chr1_+_86021935 0.189 ENSMUST00000052854.6
ENSMUST00000125083.1
ENSMUST00000152501.1
ENSMUST00000113344.1
ENSMUST00000130504.1
ENSMUST00000153247.2
Spata3





spermatogenesis associated 3





chr8_+_70539675 0.185 ENSMUST00000093454.6
Ell
elongation factor RNA polymerase II
chr11_+_53519871 0.180 ENSMUST00000120878.2
Sept8
septin 8
chr5_+_115011111 0.178 ENSMUST00000031530.5
Sppl3
signal peptide peptidase 3
chr9_-_108083330 0.176 ENSMUST00000159372.1
ENSMUST00000160249.1
Rnf123

ring finger protein 123

chr5_-_51567717 0.175 ENSMUST00000127135.1
ENSMUST00000151104.1
Ppargc1a

peroxisome proliferative activated receptor, gamma, coactivator 1 alpha

chr4_-_129742275 0.171 ENSMUST00000066257.5
Khdrbs1
KH domain containing, RNA binding, signal transduction associated 1
chr7_-_25219823 0.169 ENSMUST00000058702.5
Dedd2
death effector domain-containing DNA binding protein 2
chr2_-_136387929 0.169 ENSMUST00000035264.2
ENSMUST00000077200.3
Pak7

p21 protein (Cdc42/Rac)-activated kinase 7

chr16_-_43889669 0.168 ENSMUST00000023387.7
Qtrtd1
queuine tRNA-ribosyltransferase domain containing 1
chr8_+_46163651 0.164 ENSMUST00000034048.6
ENSMUST00000145229.1
4933411K20Rik

RIKEN cDNA 4933411K20 gene

chr18_+_74442500 0.158 ENSMUST00000074157.6
Myo5b
myosin VB
chr7_+_44896125 0.156 ENSMUST00000166552.1
ENSMUST00000168207.1
Fuz

fuzzy homolog (Drosophila)

chr9_+_53537021 0.149 ENSMUST00000035850.7
Npat
nuclear protein in the AT region
chr18_+_53176345 0.146 ENSMUST00000037850.5
Snx2
sorting nexin 2

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
1.3 5.3 GO:0051311 spindle assembly involved in female meiosis(GO:0007056) meiotic metaphase plate congression(GO:0051311)
1.3 6.5 GO:0010993 regulation of ubiquitin homeostasis(GO:0010993) free ubiquitin chain polymerization(GO:0010994)
1.3 3.8 GO:0031660 regulation of cyclin-dependent protein serine/threonine kinase activity involved in G2/M transition of mitotic cell cycle(GO:0031660) positive regulation of cyclin-dependent protein serine/threonine kinase activity involved in G2/M transition of mitotic cell cycle(GO:0031662)
1.1 4.4 GO:0060032 notochord regression(GO:0060032)
0.9 2.7 GO:1904760 myofibroblast differentiation(GO:0036446) regulation of myofibroblast differentiation(GO:1904760)
0.8 0.8 GO:1902460 regulation of mesenchymal stem cell proliferation(GO:1902460) positive regulation of mesenchymal stem cell proliferation(GO:1902462)
0.6 3.2 GO:0045163 clustering of voltage-gated potassium channels(GO:0045163)
0.6 3.2 GO:0035063 nuclear speck organization(GO:0035063)
0.6 3.4 GO:0003383 apical constriction(GO:0003383)
0.5 5.9 GO:0002315 marginal zone B cell differentiation(GO:0002315)
0.4 4.8 GO:0042487 regulation of odontogenesis of dentin-containing tooth(GO:0042487)
0.4 1.3 GO:0006116 NADH oxidation(GO:0006116) glycerol-3-phosphate catabolic process(GO:0046168)
0.4 2.1 GO:0019230 proprioception(GO:0019230)
0.4 1.2 GO:0030200 heparan sulfate proteoglycan catabolic process(GO:0030200)
0.4 1.2 GO:1904274 tricellular tight junction assembly(GO:1904274)
0.4 1.1 GO:0036500 ATF6-mediated unfolded protein response(GO:0036500)
0.4 3.4 GO:0030035 microspike assembly(GO:0030035)
0.4 1.1 GO:2001137 positive regulation of endocytic recycling(GO:2001137)
0.3 2.4 GO:0035948 positive regulation of gluconeogenesis by positive regulation of transcription from RNA polymerase II promoter(GO:0035948) regulation of cellular ketone metabolic process by positive regulation of transcription from RNA polymerase II promoter(GO:0072366)
0.3 2.4 GO:0000320 re-entry into mitotic cell cycle(GO:0000320)
0.3 1.0 GO:0016332 establishment or maintenance of polarity of embryonic epithelium(GO:0016332)
0.3 1.0 GO:0035574 histone H4-K20 demethylation(GO:0035574)
0.3 2.1 GO:0070779 D-aspartate transport(GO:0070777) D-aspartate import(GO:0070779)
0.3 1.2 GO:0089711 L-glutamate transmembrane transport(GO:0089711)
0.3 0.9 GO:1902162 regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator(GO:1902162)
0.3 1.1 GO:0071930 negative regulation of transcription involved in G1/S transition of mitotic cell cycle(GO:0071930)
0.2 0.7 GO:0007181 transforming growth factor beta receptor complex assembly(GO:0007181) chorionic trophoblast cell proliferation(GO:0097360) regulation of chorionic trophoblast cell proliferation(GO:1901382)
0.2 2.9 GO:0061302 smooth muscle cell-matrix adhesion(GO:0061302)
0.2 0.9 GO:2001271 negative regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:2001271)
0.2 3.2 GO:0048194 Golgi vesicle budding(GO:0048194)
0.2 2.5 GO:0070933 histone H4 deacetylation(GO:0070933)
0.2 0.6 GO:0060023 soft palate development(GO:0060023)
0.2 0.8 GO:0070125 mitochondrial translational elongation(GO:0070125)
0.2 0.8 GO:0038163 thrombopoietin-mediated signaling pathway(GO:0038163)
0.2 1.0 GO:0035616 histone H2B conserved C-terminal lysine deubiquitination(GO:0035616)
0.2 0.5 GO:0036292 DNA rewinding(GO:0036292)
0.2 1.4 GO:0031914 negative regulation of synaptic plasticity(GO:0031914)
0.2 0.5 GO:2000314 negative regulation of fibroblast growth factor receptor signaling pathway involved in neural plate anterior/posterior pattern formation(GO:2000314)
0.1 0.7 GO:0072235 distal convoluted tubule development(GO:0072025) metanephric collecting duct development(GO:0072205) metanephric distal convoluted tubule development(GO:0072221) metanephric distal tubule development(GO:0072235)
0.1 0.6 GO:0031581 hemidesmosome assembly(GO:0031581)
0.1 3.1 GO:0045780 positive regulation of bone resorption(GO:0045780) positive regulation of bone remodeling(GO:0046852)
0.1 0.7 GO:0006344 maintenance of chromatin silencing(GO:0006344)
0.1 0.7 GO:0007089 traversing start control point of mitotic cell cycle(GO:0007089) cellular response to actinomycin D(GO:0072717)
0.1 1.5 GO:0060539 diaphragm development(GO:0060539)
0.1 1.5 GO:1902231 positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage(GO:1902231)
0.1 1.6 GO:0060481 lobar bronchus epithelium development(GO:0060481) lobar bronchus development(GO:0060482)
0.1 0.6 GO:0071500 cellular response to nitrosative stress(GO:0071500)
0.1 2.2 GO:0032897 negative regulation of viral transcription(GO:0032897)
0.1 1.3 GO:0018065 protein-cofactor linkage(GO:0018065)
0.1 1.0 GO:0032286 central nervous system myelin maintenance(GO:0032286)
0.1 0.8 GO:0010831 positive regulation of myotube differentiation(GO:0010831)
0.1 0.5 GO:0075525 viral translational termination-reinitiation(GO:0075525)
0.1 0.5 GO:0048630 skeletal muscle tissue growth(GO:0048630)
0.1 1.3 GO:0014842 regulation of skeletal muscle satellite cell proliferation(GO:0014842)
0.1 0.6 GO:0098964 dendritic transport of ribonucleoprotein complex(GO:0098961) dendritic transport of messenger ribonucleoprotein complex(GO:0098963) anterograde dendritic transport of messenger ribonucleoprotein complex(GO:0098964)
0.1 1.1 GO:0090209 negative regulation of triglyceride metabolic process(GO:0090209)
0.1 0.7 GO:1903003 positive regulation of protein deubiquitination(GO:1903003)
0.1 1.5 GO:0015693 magnesium ion transport(GO:0015693)
0.1 0.2 GO:1904879 positive regulation of calcium ion transmembrane transport via high voltage-gated calcium channel(GO:1904879)
0.1 0.9 GO:0045199 maintenance of epithelial cell apical/basal polarity(GO:0045199)
0.1 0.2 GO:0060017 parathyroid gland development(GO:0060017)
0.1 0.4 GO:0098535 de novo centriole assembly(GO:0098535)
0.1 0.3 GO:1902031 regulation of NADP metabolic process(GO:1902031)
0.1 0.2 GO:0032241 positive regulation of nucleobase-containing compound transport(GO:0032241)
0.1 0.6 GO:0030322 stabilization of membrane potential(GO:0030322)
0.1 0.4 GO:0071294 cellular response to zinc ion(GO:0071294)
0.1 0.2 GO:0021812 neuronal-glial interaction involved in cerebral cortex radial glia guided migration(GO:0021812)
0.0 1.0 GO:0051205 protein insertion into membrane(GO:0051205)
0.0 1.9 GO:0035329 hippo signaling(GO:0035329)
0.0 0.2 GO:0042796 snRNA transcription from RNA polymerase III promoter(GO:0042796)
0.0 1.4 GO:0046677 response to antibiotic(GO:0046677)
0.0 0.4 GO:0000050 urea cycle(GO:0000050) urea metabolic process(GO:0019627)
0.0 3.0 GO:0051489 regulation of filopodium assembly(GO:0051489)
0.0 0.2 GO:2000182 regulation of progesterone biosynthetic process(GO:2000182)
0.0 0.3 GO:0061052 negative regulation of cell growth involved in cardiac muscle cell development(GO:0061052)
0.0 0.5 GO:0007602 phototransduction(GO:0007602)
0.0 0.8 GO:0051123 RNA polymerase II transcriptional preinitiation complex assembly(GO:0051123)
0.0 1.2 GO:0007520 myoblast fusion(GO:0007520)
0.0 1.1 GO:0070979 protein K11-linked ubiquitination(GO:0070979)
0.0 4.5 GO:0048706 embryonic skeletal system development(GO:0048706)
0.0 0.3 GO:0019433 triglyceride catabolic process(GO:0019433)
0.0 0.8 GO:0060441 epithelial tube branching involved in lung morphogenesis(GO:0060441)
0.0 0.2 GO:0032439 endosome localization(GO:0032439)
0.0 2.1 GO:2000045 regulation of G1/S transition of mitotic cell cycle(GO:2000045)
0.0 0.2 GO:0051533 positive regulation of NFAT protein import into nucleus(GO:0051533)
0.0 0.2 GO:0046826 negative regulation of protein export from nucleus(GO:0046826)
0.0 0.7 GO:0043171 peptide catabolic process(GO:0043171)
0.0 2.5 GO:0007093 mitotic cell cycle checkpoint(GO:0007093)
0.0 2.0 GO:0007098 centrosome cycle(GO:0007098)
0.0 0.1 GO:0045759 negative regulation of action potential(GO:0045759)
0.0 3.1 GO:0000910 cytokinesis(GO:0000910)
0.0 0.4 GO:0007064 mitotic sister chromatid cohesion(GO:0007064)
0.0 0.1 GO:0035826 rubidium ion transport(GO:0035826) cellular hypotonic response(GO:0071476)
0.0 0.4 GO:2000311 regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity(GO:2000311)
0.0 1.0 GO:0007043 cell-cell junction assembly(GO:0007043)
0.0 0.5 GO:0035335 peptidyl-tyrosine dephosphorylation(GO:0035335)
0.0 0.1 GO:0034498 early endosome to Golgi transport(GO:0034498)
0.0 0.5 GO:0051973 positive regulation of telomerase activity(GO:0051973)
0.0 0.1 GO:0015868 purine ribonucleotide transport(GO:0015868)
0.0 0.1 GO:0000083 regulation of transcription involved in G1/S transition of mitotic cell cycle(GO:0000083)
0.0 0.2 GO:0032410 negative regulation of transporter activity(GO:0032410)
0.0 0.1 GO:0006701 progesterone biosynthetic process(GO:0006701)
0.0 0.1 GO:0090527 actin filament reorganization(GO:0090527)
0.0 0.2 GO:0060706 cell differentiation involved in embryonic placenta development(GO:0060706)
0.0 0.2 GO:0016188 synaptic vesicle maturation(GO:0016188)
0.0 0.1 GO:0030854 positive regulation of granulocyte differentiation(GO:0030854)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
1.4 4.2 GO:1990423 RZZ complex(GO:1990423)
0.9 3.8 GO:0000942 condensed nuclear chromosome outer kinetochore(GO:0000942)
0.6 5.3 GO:0072687 meiotic spindle(GO:0072687)
0.5 2.1 GO:0008537 proteasome activator complex(GO:0008537)
0.4 3.4 GO:0033269 internode region of axon(GO:0033269)
0.3 4.4 GO:0097542 ciliary tip(GO:0097542)
0.3 7.5 GO:0005680 anaphase-promoting complex(GO:0005680)
0.3 1.4 GO:0035189 Rb-E2F complex(GO:0035189)
0.3 1.1 GO:0005594 collagen type IX trimer(GO:0005594)
0.3 1.3 GO:0009331 glycerol-3-phosphate dehydrogenase complex(GO:0009331)
0.2 0.7 GO:0048179 activin receptor complex(GO:0048179)
0.2 1.4 GO:0044305 calyx of Held(GO:0044305)
0.2 1.4 GO:0001520 outer dense fiber(GO:0001520)
0.2 0.8 GO:0043259 laminin-1 complex(GO:0005606) laminin-10 complex(GO:0043259)
0.2 1.2 GO:0042627 chylomicron(GO:0042627)
0.1 0.8 GO:0000125 PCAF complex(GO:0000125)
0.1 1.1 GO:0034362 low-density lipoprotein particle(GO:0034362)
0.1 5.9 GO:0030173 integral component of Golgi membrane(GO:0030173)
0.1 1.4 GO:0005862 muscle thin filament tropomyosin(GO:0005862)
0.1 4.1 GO:0030673 axolemma(GO:0030673)
0.1 0.2 GO:0044614 nuclear pore cytoplasmic filaments(GO:0044614)
0.1 0.5 GO:0090571 RNA polymerase II transcription repressor complex(GO:0090571)
0.1 1.0 GO:0017146 NMDA selective glutamate receptor complex(GO:0017146)
0.1 0.4 GO:0005786 signal recognition particle, endoplasmic reticulum targeting(GO:0005786)
0.1 0.2 GO:0046696 lipopolysaccharide receptor complex(GO:0046696)
0.0 0.5 GO:0005892 acetylcholine-gated channel complex(GO:0005892)
0.0 0.1 GO:0030905 retromer, tubulation complex(GO:0030905)
0.0 1.3 GO:0005689 U12-type spliceosomal complex(GO:0005689)
0.0 0.2 GO:1990357 terminal web(GO:1990357)
0.0 2.2 GO:0000307 cyclin-dependent protein kinase holoenzyme complex(GO:0000307)
0.0 0.7 GO:0071564 npBAF complex(GO:0071564)
0.0 2.4 GO:0016459 myosin complex(GO:0016459)
0.0 5.3 GO:0030496 midbody(GO:0030496)
0.0 0.2 GO:0071556 integral component of cytoplasmic side of endoplasmic reticulum membrane(GO:0071458) integral component of lumenal side of endoplasmic reticulum membrane(GO:0071556) lumenal side of endoplasmic reticulum membrane(GO:0098553)
0.0 2.4 GO:0031985 Golgi cisterna(GO:0031985)
0.0 2.7 GO:0005776 autophagosome(GO:0005776)
0.0 0.6 GO:0035253 ciliary rootlet(GO:0035253)
0.0 0.4 GO:0005852 eukaryotic translation initiation factor 3 complex(GO:0005852)
0.0 0.1 GO:0097504 Gemini of coiled bodies(GO:0097504)
0.0 2.1 GO:0035097 histone methyltransferase complex(GO:0035097)
0.0 3.1 GO:0031225 anchored component of membrane(GO:0031225)
0.0 0.1 GO:0031251 PAN complex(GO:0031251)
0.0 2.4 GO:0016605 PML body(GO:0016605)
0.0 0.2 GO:0097197 tetraspanin-enriched microdomain(GO:0097197)
0.0 0.2 GO:1990454 L-type voltage-gated calcium channel complex(GO:1990454)
0.0 0.8 GO:0016592 mediator complex(GO:0016592)
0.0 0.1 GO:0035749 myelin sheath adaxonal region(GO:0035749)
0.0 1.7 GO:0030136 clathrin-coated vesicle(GO:0030136)
0.0 0.5 GO:0043596 nuclear replication fork(GO:0043596)
0.0 1.1 GO:0000502 proteasome complex(GO:0000502)
0.0 0.5 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.0 0.4 GO:0055038 recycling endosome membrane(GO:0055038)
0.0 1.3 GO:0000793 condensed chromosome(GO:0000793)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
2.0 5.9 GO:0033829 O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase activity(GO:0033829)
0.9 3.8 GO:0061575 cyclin-dependent protein serine/threonine kinase activator activity(GO:0061575)
0.5 1.4 GO:0001565 phorbol ester receptor activity(GO:0001565) non-kinase phorbol ester receptor activity(GO:0001566)
0.4 1.3 GO:0016901 glycerol-3-phosphate dehydrogenase activity(GO:0004368) oxidoreductase activity, acting on the CH-OH group of donors, quinone or similar compound as acceptor(GO:0016901)
0.4 1.2 GO:0070052 collagen V binding(GO:0070052)
0.4 2.1 GO:0015501 glutamate:sodium symporter activity(GO:0015501)
0.3 2.9 GO:0038062 protein tyrosine kinase collagen receptor activity(GO:0038062)
0.3 1.0 GO:0030368 interleukin-17 receptor activity(GO:0030368)
0.3 1.0 GO:0035575 histone demethylase activity (H4-K20 specific)(GO:0035575)
0.2 2.1 GO:0061133 endopeptidase activator activity(GO:0061133)
0.2 0.5 GO:0035851 Krueppel-associated box domain binding(GO:0035851)
0.2 1.3 GO:0004852 uroporphyrinogen-III synthase activity(GO:0004852)
0.2 0.6 GO:0034190 apolipoprotein receptor binding(GO:0034190)
0.2 0.7 GO:0016361 activin receptor activity, type I(GO:0016361)
0.2 2.3 GO:0030169 low-density lipoprotein particle binding(GO:0030169)
0.2 1.4 GO:0004128 cytochrome-b5 reductase activity, acting on NAD(P)H(GO:0004128)
0.1 6.7 GO:0061631 ubiquitin conjugating enzyme activity(GO:0061631)
0.1 4.9 GO:1990841 promoter-specific chromatin binding(GO:1990841)
0.1 0.4 GO:0030171 voltage-gated proton channel activity(GO:0030171)
0.1 4.8 GO:0005109 frizzled binding(GO:0005109)
0.1 3.4 GO:0032266 phosphatidylinositol-3-phosphate binding(GO:0032266)
0.1 2.1 GO:0031078 histone deacetylase activity (H3-K14 specific)(GO:0031078) NAD-dependent histone deacetylase activity (H3-K14 specific)(GO:0032041)
0.1 1.5 GO:0015197 peptide transporter activity(GO:0015197)
0.1 0.3 GO:0004473 malic enzyme activity(GO:0004470) malate dehydrogenase (decarboxylating) (NAD+) activity(GO:0004471) malate dehydrogenase (decarboxylating) (NADP+) activity(GO:0004473)
0.1 2.9 GO:0070064 proline-rich region binding(GO:0070064)
0.1 1.8 GO:0005251 delayed rectifier potassium channel activity(GO:0005251)
0.1 0.4 GO:0050436 microfibril binding(GO:0050436)
0.1 3.2 GO:0070273 phosphatidylinositol-4-phosphate binding(GO:0070273)
0.1 0.8 GO:0043208 glycosphingolipid binding(GO:0043208)
0.1 1.2 GO:0005313 L-glutamate transmembrane transporter activity(GO:0005313)
0.1 0.4 GO:0030942 endoplasmic reticulum signal peptide binding(GO:0030942)
0.1 0.7 GO:0019788 NEDD8 transferase activity(GO:0019788)
0.1 1.5 GO:0015095 magnesium ion transmembrane transporter activity(GO:0015095)
0.1 1.0 GO:0016594 glycine binding(GO:0016594)
0.1 3.0 GO:0001205 transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001205)
0.1 1.1 GO:0008353 RNA polymerase II carboxy-terminal domain kinase activity(GO:0008353)
0.1 0.8 GO:0050431 transforming growth factor beta binding(GO:0050431)
0.1 3.0 GO:0030507 spectrin binding(GO:0030507)
0.1 0.6 GO:0022841 potassium ion leak channel activity(GO:0022841)
0.0 1.1 GO:0033613 activating transcription factor binding(GO:0033613)
0.0 0.2 GO:0086056 voltage-gated calcium channel activity involved in AV node cell action potential(GO:0086056)
0.0 0.5 GO:0022848 acetylcholine-gated cation channel activity(GO:0022848)
0.0 0.5 GO:0036310 annealing helicase activity(GO:0036310)
0.0 1.0 GO:0070006 metalloaminopeptidase activity(GO:0070006)
0.0 0.1 GO:0016314 phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase activity(GO:0016314)
0.0 0.1 GO:1990460 leptin receptor binding(GO:1990460)
0.0 0.8 GO:0003746 translation elongation factor activity(GO:0003746)
0.0 2.7 GO:0016209 antioxidant activity(GO:0016209)
0.0 0.3 GO:0008420 CTD phosphatase activity(GO:0008420)
0.0 0.5 GO:0003841 1-acylglycerol-3-phosphate O-acyltransferase activity(GO:0003841)
0.0 0.3 GO:0004806 triglyceride lipase activity(GO:0004806)
0.0 0.8 GO:0017025 TBP-class protein binding(GO:0017025)
0.0 0.1 GO:0019966 interleukin-1 binding(GO:0019966)
0.0 0.4 GO:0001013 RNA polymerase I regulatory region DNA binding(GO:0001013)
0.0 0.2 GO:0042500 aspartic endopeptidase activity, intramembrane cleaving(GO:0042500)
0.0 2.4 GO:0005089 Rho guanyl-nucleotide exchange factor activity(GO:0005089)
0.0 0.6 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.0 0.7 GO:0016922 ligand-dependent nuclear receptor binding(GO:0016922)
0.0 0.5 GO:0003924 GTPase activity(GO:0003924)
0.0 0.1 GO:0015379 potassium:chloride symporter activity(GO:0015379) potassium ion symporter activity(GO:0022820)
0.0 0.2 GO:0001530 lipopolysaccharide binding(GO:0001530)
0.0 0.9 GO:0020037 heme binding(GO:0020037)
0.0 1.6 GO:0002020 protease binding(GO:0002020)
0.0 1.0 GO:0004197 cysteine-type endopeptidase activity(GO:0004197)
0.0 0.7 GO:0031593 polyubiquitin binding(GO:0031593)
0.0 0.5 GO:0008307 structural constituent of muscle(GO:0008307)
0.0 0.8 GO:0005179 hormone activity(GO:0005179)
0.0 0.1 GO:0004745 retinol dehydrogenase activity(GO:0004745)
0.0 0.4 GO:0050699 WW domain binding(GO:0050699)
0.0 4.0 GO:0005525 GTP binding(GO:0005525)
0.0 0.4 GO:0005245 voltage-gated calcium channel activity(GO:0005245)
0.0 0.5 GO:0008138 protein tyrosine/serine/threonine phosphatase activity(GO:0008138)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 4.1 SA_G1_AND_S_PHASES Cdk2, 4, and 6 bind cyclin D in G1, while cdk2/cyclin E promotes the G1/S transition.
0.2 8.4 PID_AURORA_B_PATHWAY Aurora B signaling
0.1 4.7 PID_HEDGEHOG_2PATHWAY Signaling events mediated by the Hedgehog family
0.1 3.8 PID_FOXM1_PATHWAY FOXM1 transcription factor network
0.1 0.8 PID_INTEGRIN4_PATHWAY Alpha6 beta4 integrin-ligand interactions
0.1 3.5 PID_HNF3B_PATHWAY FOXA2 and FOXA3 transcription factor networks
0.1 2.4 PID_HNF3A_PATHWAY FOXA1 transcription factor network
0.0 0.5 PID_RHODOPSIN_PATHWAY Visual signal transduction: Rods
0.0 1.2 PID_GLYPICAN_1PATHWAY Glypican 1 network
0.0 1.9 PID_NETRIN_PATHWAY Netrin-mediated signaling events
0.0 3.5 SIG_INSULIN_RECEPTOR_PATHWAY_IN_CARDIAC_MYOCYTES Genes related to the insulin receptor pathway
0.0 1.7 NABA_COLLAGENS Genes encoding collagen proteins
0.0 2.3 PID_HDAC_CLASSII_PATHWAY Signaling events mediated by HDAC Class II
0.0 2.1 PID_ERA_GENOMIC_PATHWAY Validated nuclear estrogen receptor alpha network
0.0 3.7 WNT_SIGNALING Genes related to Wnt-mediated signal transduction
0.0 1.5 PID_TGFBR_PATHWAY TGF-beta receptor signaling
0.0 1.0 PID_FGF_PATHWAY FGF signaling pathway
0.0 0.2 PID_TCR_JNK_PATHWAY JNK signaling in the CD4+ TCR pathway
0.0 0.9 PID_TNF_PATHWAY TNF receptor signaling pathway
0.0 0.5 PID_LIS1_PATHWAY Lissencephaly gene (LIS1) in neuronal migration and development
0.0 0.5 PID_ERBB2_ERBB3_PATHWAY ErbB2/ErbB3 signaling events
0.0 0.2 PID_P38_ALPHA_BETA_DOWNSTREAM_PATHWAY Signaling mediated by p38-alpha and p38-beta
0.0 0.1 PID_THROMBIN_PAR1_PATHWAY PAR1-mediated thrombin signaling events

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 11.3 REACTOME_PHOSPHORYLATION_OF_THE_APC_C Genes involved in Phosphorylation of the APC/C
0.3 5.1 REACTOME_PRE_NOTCH_PROCESSING_IN_GOLGI Genes involved in Pre-NOTCH Processing in Golgi
0.2 5.3 REACTOME_TIGHT_JUNCTION_INTERACTIONS Genes involved in Tight junction interactions
0.1 2.4 REACTOME_SYNTHESIS_SECRETION_AND_DEACYLATION_OF_GHRELIN Genes involved in Synthesis, Secretion, and Deacylation of Ghrelin
0.1 3.5 REACTOME_PRE_NOTCH_TRANSCRIPTION_AND_TRANSLATION Genes involved in Pre-NOTCH Transcription and Translation
0.1 1.2 REACTOME_DEGRADATION_OF_THE_EXTRACELLULAR_MATRIX Genes involved in Degradation of the extracellular matrix
0.1 0.5 REACTOME_OLFACTORY_SIGNALING_PATHWAY Genes involved in Olfactory Signaling Pathway
0.1 1.4 REACTOME_ACTIVATION_OF_RAC Genes involved in Activation of Rac
0.1 3.1 REACTOME_ACTIVATED_NOTCH1_TRANSMITS_SIGNAL_TO_THE_NUCLEUS Genes involved in Activated NOTCH1 Transmits Signal to the Nucleus
0.1 0.7 REACTOME_SIGNALING_BY_NODAL Genes involved in Signaling by NODAL
0.1 0.5 REACTOME_PRESYNAPTIC_NICOTINIC_ACETYLCHOLINE_RECEPTORS Genes involved in Presynaptic nicotinic acetylcholine receptors
0.1 1.3 REACTOME_METABOLISM_OF_PORPHYRINS Genes involved in Metabolism of porphyrins
0.1 1.9 REACTOME_SIGNALING_BY_HIPPO Genes involved in Signaling by Hippo
0.1 4.8 REACTOME_CLASS_B_2_SECRETIN_FAMILY_RECEPTORS Genes involved in Class B/2 (Secretin family receptors)
0.1 3.3 REACTOME_AMINO_ACID_AND_OLIGOPEPTIDE_SLC_TRANSPORTERS Genes involved in Amino acid and oligopeptide SLC transporters
0.1 1.8 REACTOME_SYNTHESIS_OF_PA Genes involved in Synthesis of PA
0.1 1.4 REACTOME_STRIATED_MUSCLE_CONTRACTION Genes involved in Striated Muscle Contraction
0.1 2.8 REACTOME_TRANSCRIPTIONAL_ACTIVITY_OF_SMAD2_SMAD3_SMAD4_HETEROTRIMER Genes involved in Transcriptional activity of SMAD2/SMAD3:SMAD4 heterotrimer
0.0 4.4 REACTOME_MITOTIC_PROMETAPHASE Genes involved in Mitotic Prometaphase
0.0 1.8 REACTOME_SIGNALING_BY_NOTCH1 Genes involved in Signaling by NOTCH1
0.0 1.0 REACTOME_SIGNALING_BY_FGFR Genes involved in Signaling by FGFR
0.0 0.1 REACTOME_NEGATIVE_REGULATION_OF_THE_PI3K_AKT_NETWORK Genes involved in Negative regulation of the PI3K/AKT network
0.0 2.9 REACTOME_NRAGE_SIGNALS_DEATH_THROUGH_JNK Genes involved in NRAGE signals death through JNK
0.0 0.7 REACTOME_AKT_PHOSPHORYLATES_TARGETS_IN_THE_CYTOSOL Genes involved in AKT phosphorylates targets in the cytosol
0.0 1.7 REACTOME_COLLAGEN_FORMATION Genes involved in Collagen formation
0.0 0.2 REACTOME_INHIBITION_OF_INSULIN_SECRETION_BY_ADRENALINE_NORADRENALINE Genes involved in Inhibition of Insulin Secretion by Adrenaline/Noradrenaline
0.0 1.3 REACTOME_RNA_POL_II_PRE_TRANSCRIPTION_EVENTS Genes involved in RNA Polymerase II Pre-transcription Events
0.0 0.5 REACTOME_SIGNALING_BY_ROBO_RECEPTOR Genes involved in Signaling by Robo receptor
0.0 0.8 REACTOME_PLATELET_AGGREGATION_PLUG_FORMATION Genes involved in Platelet Aggregation (Plug Formation)
0.0 3.8 REACTOME_ANTIGEN_PROCESSING_UBIQUITINATION_PROTEASOME_DEGRADATION Genes involved in Antigen processing: Ubiquitination & Proteasome degradation
0.0 0.8 REACTOME_ACTIVATION_OF_CHAPERONE_GENES_BY_XBP1S Genes involved in Activation of Chaperone Genes by XBP1(S)