Motif ID: Fosb

Z-value: 0.375


Transcription factors associated with Fosb:

Gene SymbolEntrez IDGene Name
Fosb ENSMUSG00000003545.2 Fosb

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Fosbmm10_v2_chr7_-_19310035_19310050-0.153.8e-01Click!


Activity profile for motif Fosb.

activity profile for motif Fosb


Sorted Z-values histogram for motif Fosb

Sorted Z-values for motif Fosb



Network of associatons between targets according to the STRING database.



First level regulatory network of Fosb

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.
View svg image
View png image

Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr16_+_78930940 1.769 ENSMUST00000114216.1
ENSMUST00000069148.6
ENSMUST00000023568.7
 Chodl


chondrolectin


chr10_-_64090241 1.614 ENSMUST00000133588.1
 Lrrtm3
leucine rich repeat transmembrane neuronal 3
chr6_+_17463927 1.312 ENSMUST00000115442.1
 Met
met proto-oncogene
chr8_+_36489191 1.222 ENSMUST00000171777.1
 6430573F11Rik
RIKEN cDNA 6430573F11 gene
chr10_-_64090265 1.190 ENSMUST00000105439.1
 Lrrtm3
leucine rich repeat transmembrane neuronal 3
chr13_-_113663670 1.081 ENSMUST00000054650.4
 Hspb3
heat shock protein 3
chr8_-_8639363 1.000 ENSMUST00000152698.1
 Efnb2
ephrin B2
chr17_+_35841668 0.884 ENSMUST00000174124.1
 Mdc1
mediator of DNA damage checkpoint 1
chr14_+_80000292 0.708 ENSMUST00000088735.3
 Olfm4
olfactomedin 4
chr15_-_102257306 0.699 ENSMUST00000135466.1
 Rarg
retinoic acid receptor, gamma
chr3_+_123267445 0.630 ENSMUST00000047923.7
 Sec24d
Sec24 related gene family, member D (S. cerevisiae)
chr2_+_118663235 0.627 ENSMUST00000099557.3
 Pak6
p21 protein (Cdc42/Rac)-activated kinase 6
chr6_-_113934679 0.565 ENSMUST00000101044.2
 Atp2b2
ATPase, Ca++ transporting, plasma membrane 2
chr15_-_102257449 0.564 ENSMUST00000043172.8
 Rarg
retinoic acid receptor, gamma
chr9_+_114978507 0.560 ENSMUST00000183104.1
 Osbpl10
oxysterol binding protein-like 10
chr2_-_45110241 0.520 ENSMUST00000177302.1
 Zeb2
zinc finger E-box binding homeobox 2
chr14_+_27622433 0.508 ENSMUST00000090302.5
 Erc2
ELKS/RAB6-interacting/CAST family member 2
chr3_+_55461758 0.498 ENSMUST00000070418.4
 Dclk1
doublecortin-like kinase 1
chr9_+_104566677 0.487 ENSMUST00000157006.1
 Cpne4
copine IV
chr2_-_151632471 0.461 ENSMUST00000137936.1
ENSMUST00000146172.1
ENSMUST00000094456.3
ENSMUST00000148755.1
ENSMUST00000109875.1
ENSMUST00000028951.7
ENSMUST00000109877.3
 Snph






syntaphilin






chr14_+_79426454 0.434 ENSMUST00000061222.7
 Kbtbd7
kelch repeat and BTB (POZ) domain containing 7
chr19_+_5447692 0.431 ENSMUST00000025850.5
 Fosl1
fos-like antigen 1
chr16_+_17561885 0.426 ENSMUST00000171002.1
ENSMUST00000023441.4
 P2rx6

purinergic receptor P2X, ligand-gated ion channel, 6

chr6_+_86849488 0.407 ENSMUST00000089519.6
ENSMUST00000113668.1
 Aak1

AP2 associated kinase 1

chr11_-_120630516 0.395 ENSMUST00000106181.1
 Mafg
v-maf musculoaponeurotic fibrosarcoma oncogene family, protein G (avian)
chr8_+_107293500 0.394 ENSMUST00000151114.1
ENSMUST00000075922.4
ENSMUST00000125721.1
 Nfat5


nuclear factor of activated T cells 5


chr7_-_29505447 0.362 ENSMUST00000183096.1
ENSMUST00000085809.4
 Sipa1l3

signal-induced proliferation-associated 1 like 3

chr2_-_29253001 0.317 ENSMUST00000071201.4
 Ntng2
netrin G2
chr17_+_35841491 0.310 ENSMUST00000082337.6
 Mdc1
mediator of DNA damage checkpoint 1
chr10_+_26078255 0.304 ENSMUST00000041011.3
 Gm9767
predicted gene 9767
chr1_+_134560190 0.292 ENSMUST00000112198.1
ENSMUST00000112197.1
 Kdm5b

lysine (K)-specific demethylase 5B

chr10_+_116143881 0.289 ENSMUST00000105271.2
 Ptprr
protein tyrosine phosphatase, receptor type, R
chr7_-_133782721 0.277 ENSMUST00000063669.1
 Dhx32
DEAH (Asp-Glu-Ala-His) box polypeptide 32
chr11_-_3914664 0.253 ENSMUST00000109995.1
ENSMUST00000051207.1
 Slc35e4

solute carrier family 35, member E4

chr15_+_102503722 0.247 ENSMUST00000096145.4
 Gm10337
predicted gene 10337
chr2_-_25224653 0.229 ENSMUST00000043584.4
 Tubb4b
tubulin, beta 4B class IVB
chr2_+_156475844 0.207 ENSMUST00000103135.1
 Epb4.1l1
erythrocyte protein band 4.1-like 1
chrX_+_73675500 0.205 ENSMUST00000171398.1
 Slc6a8
solute carrier family 6 (neurotransmitter transporter, creatine), member 8
chr12_-_84194007 0.202 ENSMUST00000110294.1
 Elmsan1
ELM2 and Myb/SANT-like domain containing 1
chr5_-_5265224 0.196 ENSMUST00000115450.1
 Cdk14
cyclin-dependent kinase 14
chr6_-_124769548 0.196 ENSMUST00000149652.1
ENSMUST00000112476.1
ENSMUST00000004378.8
 Eno2


enolase 2, gamma neuronal


chr18_+_40258361 0.183 ENSMUST00000091927.4
 Kctd16
potassium channel tetramerisation domain containing 16
chr2_+_156475803 0.173 ENSMUST00000029155.8
 Epb4.1l1
erythrocyte protein band 4.1-like 1
chr7_-_80401707 0.170 ENSMUST00000120753.1
 Furin
furin (paired basic amino acid cleaving enzyme)
chr9_+_122888471 0.168 ENSMUST00000063980.6
 Zkscan7
zinc finger with KRAB and SCAN domains 7
chr9_+_44240668 0.168 ENSMUST00000092426.3
 Ccdc153
coiled-coil domain containing 153
chr1_-_182517447 0.156 ENSMUST00000068505.8
 Capn2
calpain 2
chr11_+_80428598 0.155 ENSMUST00000173938.1
ENSMUST00000017572.7
 Psmd11

proteasome (prosome, macropain) 26S subunit, non-ATPase, 11

chr14_-_55758458 0.146 ENSMUST00000001497.7
 Cideb
cell death-inducing DNA fragmentation factor, alpha subunit-like effector B
chr5_-_86676346 0.132 ENSMUST00000038448.6
 Tmprss11bnl
transmembrane protease, serine 11b N terminal like
chr13_-_54611274 0.128 ENSMUST00000049575.7
 Cltb
clathrin, light polypeptide (Lcb)
chr1_+_86064619 0.124 ENSMUST00000027432.8
 Psmd1
proteasome (prosome, macropain) 26S subunit, non-ATPase, 1
chr16_-_4880284 0.120 ENSMUST00000037843.6
 Ubald1
UBA-like domain containing 1
chr17_-_30612613 0.105 ENSMUST00000167624.1
ENSMUST00000024823.6
 Glo1

glyoxalase 1

chr13_-_54611332 0.095 ENSMUST00000091609.4
 Cltb
clathrin, light polypeptide (Lcb)
chr1_+_134560157 0.093 ENSMUST00000047714.7
 Kdm5b
lysine (K)-specific demethylase 5B
chr9_-_119977250 0.087 ENSMUST00000035101.7
 Csrnp1
cysteine-serine-rich nuclear protein 1
chr11_-_96075655 0.059 ENSMUST00000090541.5
 Atp5g1
ATP synthase, H+ transporting, mitochondrial F0 complex, subunit c1 (subunit 9)
chr17_-_45592262 0.052 ENSMUST00000164769.1
 Slc29a1
solute carrier family 29 (nucleoside transporters), member 1
chr2_+_167777467 0.030 ENSMUST00000139927.1
ENSMUST00000127441.1
 Gm14321

predicted gene 14321

chr4_-_43558386 0.029 ENSMUST00000130353.1
 Tln1
talin 1
chr11_-_96075581 0.028 ENSMUST00000107686.1
ENSMUST00000107684.1
 Atp5g1

ATP synthase, H+ transporting, mitochondrial F0 complex, subunit c1 (subunit 9)

chr17_-_45592485 0.028 ENSMUST00000166119.1
 Slc29a1
solute carrier family 29 (nucleoside transporters), member 1
chr4_-_140665891 0.025 ENSMUST00000069623.5
 Arhgef10l
Rho guanine nucleotide exchange factor (GEF) 10-like
chr7_-_127946725 0.015 ENSMUST00000118755.1
ENSMUST00000094026.3
 Prss36

protease, serine, 36

chr9_+_78615501 0.015 ENSMUST00000093812.4
 Cd109
CD109 antigen
chr6_-_129533267 0.013 ENSMUST00000181594.1
 1700101I11Rik
RIKEN cDNA 1700101I11 gene
chr11_+_78188737 0.012 ENSMUST00000108322.2
 Rab34
RAB34, member of RAS oncogene family
chr9_+_96259246 0.011 ENSMUST00000179065.1
ENSMUST00000165768.2
 Tfdp2

transcription factor Dp 2

chr11_+_77801325 0.009 ENSMUST00000151373.2
ENSMUST00000172303.2
ENSMUST00000130305.2
ENSMUST00000164334.1
ENSMUST00000092884.4
 Myo18a




myosin XVIIIA




chr7_-_4778141 0.004 ENSMUST00000094892.5
 Il11
interleukin 11

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.3 GO:0003430 growth plate cartilage chondrocyte growth(GO:0003430)
0.2 1.3 GO:0070494 regulation of thrombin receptor signaling pathway(GO:0070494) negative regulation of thrombin receptor signaling pathway(GO:0070495)
0.2 2.8 GO:1902004 positive regulation of beta-amyloid formation(GO:1902004)
0.1 1.0 GO:1903847 regulation of aorta morphogenesis(GO:1903847) positive regulation of aorta morphogenesis(GO:1903849)
0.1 1.2 GO:0002098 tRNA wobble uridine modification(GO:0002098)
0.1 0.4 GO:0035937 estrogen secretion(GO:0035937) estradiol secretion(GO:0035938) regulation of estrogen secretion(GO:2000861) regulation of estradiol secretion(GO:2000864)
0.1 0.6 GO:0048840 otolith development(GO:0048840)
0.1 0.5 GO:1903056 positive regulation of lens fiber cell differentiation(GO:1902748) regulation of melanosome organization(GO:1903056)
0.1 0.3 GO:0038128 ERBB2 signaling pathway(GO:0038128)
0.1 0.4 GO:0007296 vitellogenesis(GO:0007296)
0.0 0.6 GO:0090110 cargo loading into COPII-coated vesicle(GO:0090110)
0.0 0.2 GO:0090472 dibasic protein processing(GO:0090472)
0.0 0.2 GO:0016540 protein autoprocessing(GO:0016540)
0.0 0.4 GO:0070884 regulation of calcineurin-NFAT signaling cascade(GO:0070884)
0.0 0.4 GO:0033198 response to ATP(GO:0033198)
0.0 0.7 GO:1900026 positive regulation of substrate adhesion-dependent cell spreading(GO:1900026)
0.0 0.4 GO:2000369 regulation of clathrin-mediated endocytosis(GO:2000369)
0.0 0.5 GO:0021952 central nervous system projection neuron axonogenesis(GO:0021952)
0.0 0.1 GO:0015862 uridine transport(GO:0015862)
0.0 0.1 GO:0019243 methylglyoxal catabolic process to D-lactate via S-lactoyl-glutathione(GO:0019243) methylglyoxal catabolic process(GO:0051596) methylglyoxal catabolic process to lactate(GO:0061727)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 GO:0061689 tricellular tight junction(GO:0061689)
0.1 0.7 GO:0042581 specific granule(GO:0042581)
0.0 0.6 GO:0030127 COPII vesicle coat(GO:0030127)
0.0 0.4 GO:0071439 clathrin complex(GO:0071439)
0.0 0.2 GO:0000308 cytoplasmic cyclin-dependent protein kinase holoenzyme complex(GO:0000308)
0.0 0.4 GO:0012510 trans-Golgi network transport vesicle membrane(GO:0012510)
0.0 0.4 GO:0031229 integral component of nuclear inner membrane(GO:0005639) intrinsic component of nuclear inner membrane(GO:0031229)
0.0 0.2 GO:0045298 tubulin complex(GO:0045298)
0.0 0.2 GO:0000015 phosphopyruvate hydratase complex(GO:0000015)
0.0 0.6 GO:0098839 postsynaptic density membrane(GO:0098839) postsynaptic specialization membrane(GO:0099634)
0.0 1.6 GO:0042734 presynaptic membrane(GO:0042734)
0.0 1.3 GO:0009925 basal plasma membrane(GO:0009925)
0.0 0.2 GO:0008541 proteasome regulatory particle, lid subcomplex(GO:0008541)
0.0 0.2 GO:0031143 pseudopodium(GO:0031143)
0.0 2.8 GO:0045211 postsynaptic membrane(GO:0045211)
0.0 0.1 GO:0031597 cytosolic proteasome complex(GO:0031597)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.3 GO:0005008 hepatocyte growth factor-activated receptor activity(GO:0005008)
0.2 1.2 GO:0016300 tRNA (uracil) methyltransferase activity(GO:0016300)
0.1 0.4 GO:0034647 histone demethylase activity (H3-trimethyl-K4 specific)(GO:0034647)
0.1 1.5 GO:0005540 hyaluronic acid binding(GO:0005540)
0.1 0.4 GO:0035381 extracellular ATP-gated cation channel activity(GO:0004931) ATP-gated ion channel activity(GO:0035381)
0.1 1.3 GO:0003708 retinoic acid receptor activity(GO:0003708)
0.1 0.2 GO:0015220 choline transmembrane transporter activity(GO:0015220)
0.0 0.6 GO:0005388 calcium-transporting ATPase activity(GO:0005388)
0.0 2.8 GO:0004860 protein kinase inhibitor activity(GO:0004860)
0.0 0.4 GO:0035612 AP-2 adaptor complex binding(GO:0035612)
0.0 0.2 GO:0004634 phosphopyruvate hydratase activity(GO:0004634)
0.0 0.2 GO:0032050 clathrin heavy chain binding(GO:0032050)
0.0 1.0 GO:0046875 ephrin receptor binding(GO:0046875)
0.0 0.5 GO:0017075 syntaxin-1 binding(GO:0017075)
0.0 0.2 GO:0048406 nerve growth factor binding(GO:0048406)
0.0 0.6 GO:0001786 phosphatidylserine binding(GO:0001786)
0.0 0.5 GO:0070412 R-SMAD binding(GO:0070412)
0.0 0.1 GO:0016846 carbon-sulfur lyase activity(GO:0016846)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 1.3 PID_RXR_VDR_PATHWAY RXR and RAR heterodimerization with other nuclear receptor
0.0 1.0 PID_EPHRINB_REV_PATHWAY Ephrin B reverse signaling
0.0 1.2 PID_ATM_PATHWAY ATM pathway
0.0 1.3 PID_A6B1_A6B4_INTEGRIN_PATHWAY a6b1 and a6b4 Integrin signaling
0.0 1.0 ST_T_CELL_SIGNAL_TRANSDUCTION T Cell Signal Transduction
0.0 0.4 PID_TCR_CALCIUM_PATHWAY Calcium signaling in the CD4+ TCR pathway
0.0 0.3 NABA_BASEMENT_MEMBRANES Genes encoding structural components of basement membranes

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.2 REACTOME_HOMOLOGOUS_RECOMBINATION_REPAIR_OF_REPLICATION_INDEPENDENT_DOUBLE_STRAND_BREAKS Genes involved in Homologous recombination repair of replication-independent double-strand breaks
0.0 0.6 REACTOME_PLATELET_CALCIUM_HOMEOSTASIS Genes involved in Platelet calcium homeostasis
0.0 0.6 REACTOME_ACTIVATION_OF_RAC Genes involved in Activation of Rac
0.0 1.3 REACTOME_SEMA4D_IN_SEMAPHORIN_SIGNALING Genes involved in Sema4D in semaphorin signaling
0.0 0.6 REACTOME_ANTIGEN_PRESENTATION_FOLDING_ASSEMBLY_AND_PEPTIDE_LOADING_OF_CLASS_I_MHC Genes involved in Antigen Presentation: Folding, assembly and peptide loading of class I MHC
0.0 0.2 REACTOME_GAMMA_CARBOXYLATION_TRANSPORT_AND_AMINO_TERMINAL_CLEAVAGE_OF_PROTEINS Genes involved in Gamma-carboxylation, transport, and amino-terminal cleavage of proteins
0.0 1.3 REACTOME_NUCLEAR_RECEPTOR_TRANSCRIPTION_PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.0 0.2 REACTOME_POST_CHAPERONIN_TUBULIN_FOLDING_PATHWAY Genes involved in Post-chaperonin tubulin folding pathway
0.0 0.2 REACTOME_GAP_JUNCTION_DEGRADATION Genes involved in Gap junction degradation