Motif ID: Fosl2_Bach2

Z-value: 0.652

Transcription factors associated with Fosl2_Bach2:

Gene SymbolEntrez IDGene Name
Bach2 ENSMUSG00000040270.10 Bach2
Fosl2 ENSMUSG00000029135.9 Fosl2

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Fosl2mm10_v2_chr5_+_32136458_321365050.797.6e-09Click!
Bach2mm10_v2_chr4_+_32238950_322389640.411.1e-02Click!





Network of associatons between targets according to the STRING database.



First level regulatory network of Fosl2_Bach2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr1_-_33907721 7.967 ENSMUST00000115161.1
ENSMUST00000062289.8
Bend6

BEN domain containing 6

chr6_+_17463927 5.595 ENSMUST00000115442.1
Met
met proto-oncogene
chr14_+_65968483 4.009 ENSMUST00000022616.6
Clu
clusterin
chr10_-_64090241 3.376 ENSMUST00000133588.1
Lrrtm3
leucine rich repeat transmembrane neuronal 3
chr18_+_32938955 3.299 ENSMUST00000042868.4
Camk4
calcium/calmodulin-dependent protein kinase IV
chrY_-_1286563 2.910 ENSMUST00000091190.5
Ddx3y
DEAD (Asp-Glu-Ala-Asp) box polypeptide 3, Y-linked
chr10_-_64090265 2.877 ENSMUST00000105439.1
Lrrtm3
leucine rich repeat transmembrane neuronal 3
chr9_+_60712989 2.850 ENSMUST00000038407.5
Larp6
La ribonucleoprotein domain family, member 6
chr6_-_124769548 2.825 ENSMUST00000149652.1
ENSMUST00000112476.1
ENSMUST00000004378.8
Eno2


enolase 2, gamma neuronal


chr9_-_20728219 2.777 ENSMUST00000034692.7
Olfm2
olfactomedin 2
chr2_+_156475803 2.771 ENSMUST00000029155.8
Epb4.1l1
erythrocyte protein band 4.1-like 1
chr16_-_22439719 2.732 ENSMUST00000079601.6
Etv5
ets variant gene 5
chr14_+_101840602 2.697 ENSMUST00000159314.1
Lmo7
LIM domain only 7
chr2_+_156475844 2.657 ENSMUST00000103135.1
Epb4.1l1
erythrocyte protein band 4.1-like 1
chr2_-_151632471 2.635 ENSMUST00000137936.1
ENSMUST00000146172.1
ENSMUST00000094456.3
ENSMUST00000148755.1
ENSMUST00000109875.1
ENSMUST00000028951.7
ENSMUST00000109877.3
Snph






syntaphilin






chr14_+_101840501 2.621 ENSMUST00000159026.1
Lmo7
LIM domain only 7
chr3_+_55461758 2.521 ENSMUST00000070418.4
Dclk1
doublecortin-like kinase 1
chr2_-_45110241 2.310 ENSMUST00000177302.1
Zeb2
zinc finger E-box binding homeobox 2
chr7_-_105482197 2.200 ENSMUST00000047040.2
Prkcdbp
protein kinase C, delta binding protein
chr4_-_42034726 2.068 ENSMUST00000084677.2
Gm21093
predicted gene, 21093
chr6_+_17463749 1.957 ENSMUST00000115443.1
Met
met proto-oncogene
chr13_-_54611274 1.953 ENSMUST00000049575.7
Cltb
clathrin, light polypeptide (Lcb)
chr8_+_95703037 1.905 ENSMUST00000073139.7
ENSMUST00000080666.7
Ndrg4

N-myc downstream regulated gene 4

chr5_-_124187150 1.893 ENSMUST00000161938.1
Pitpnm2
phosphatidylinositol transfer protein, membrane-associated 2
chr6_+_17463826 1.861 ENSMUST00000140070.1
Met
met proto-oncogene
chr13_-_113663670 1.807 ENSMUST00000054650.4
Hspb3
heat shock protein 3
chr3_-_88503331 1.795 ENSMUST00000029699.6
Lmna
lamin A
chr18_+_37955544 1.791 ENSMUST00000070709.2
ENSMUST00000177058.1
ENSMUST00000169360.2
ENSMUST00000163591.2
ENSMUST00000091932.5
Rell2




RELT-like 2




chr11_+_103103051 1.781 ENSMUST00000152971.1
Acbd4
acyl-Coenzyme A binding domain containing 4
chrX_+_71962971 1.774 ENSMUST00000048790.6
Prrg3
proline rich Gla (G-carboxyglutamic acid) 3 (transmembrane)
chr6_+_124996681 1.773 ENSMUST00000032479.4
Pianp
PILR alpha associated neural protein
chr1_-_134235420 1.769 ENSMUST00000038191.6
ENSMUST00000086465.4
Adora1

adenosine A1 receptor

chr13_-_54611332 1.752 ENSMUST00000091609.4
Cltb
clathrin, light polypeptide (Lcb)
chr13_+_54949388 1.750 ENSMUST00000026994.7
ENSMUST00000109994.2
Unc5a

unc-5 homolog A (C. elegans)

chr15_-_102257306 1.745 ENSMUST00000135466.1
Rarg
retinoic acid receptor, gamma
chr18_+_37955685 1.744 ENSMUST00000169498.2
Rell2
RELT-like 2
chr14_+_27622433 1.627 ENSMUST00000090302.5
Erc2
ELKS/RAB6-interacting/CAST family member 2
chr9_-_86695897 1.583 ENSMUST00000034989.8
Me1
malic enzyme 1, NADP(+)-dependent, cytosolic
chr5_+_37050854 1.576 ENSMUST00000043794.4
Jakmip1
janus kinase and microtubule interacting protein 1
chr15_-_102257449 1.564 ENSMUST00000043172.8
Rarg
retinoic acid receptor, gamma
chr17_-_24644933 1.501 ENSMUST00000019684.5
Slc9a3r2
solute carrier family 9 (sodium/hydrogen exchanger), member 3 regulator 2
chr3_-_88503187 1.497 ENSMUST00000120377.1
Lmna
lamin A
chrX_+_6415736 1.488 ENSMUST00000143641.3
Shroom4
shroom family member 4
chr17_-_56133817 1.476 ENSMUST00000167545.1
Sema6b
sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6B
chr1_+_165302625 1.466 ENSMUST00000111450.1
Gpr161
G protein-coupled receptor 161
chrX_-_8132770 1.427 ENSMUST00000130832.1
ENSMUST00000033506.6
ENSMUST00000115623.1
ENSMUST00000153839.1
Wdr13



WD repeat domain 13



chr1_-_30949756 1.423 ENSMUST00000076587.3
ENSMUST00000027232.7
Ptp4a1

protein tyrosine phosphatase 4a1

chr10_+_86779000 1.393 ENSMUST00000099396.2
Nt5dc3
5'-nucleotidase domain containing 3
chr17_+_35841668 1.385 ENSMUST00000174124.1
Mdc1
mediator of DNA damage checkpoint 1
chrX_+_99975570 1.344 ENSMUST00000113779.1
ENSMUST00000113776.1
ENSMUST00000113775.1
ENSMUST00000113780.1
ENSMUST00000113778.1
ENSMUST00000113781.1
ENSMUST00000113783.1
ENSMUST00000071453.2
ENSMUST00000113777.1
Eda








ectodysplasin-A








chr7_-_100547620 1.320 ENSMUST00000064334.2
D630004N19Rik
RIKEN cDNA D630004N19 gene
chr10_+_116143881 1.241 ENSMUST00000105271.2
Ptprr
protein tyrosine phosphatase, receptor type, R
chr9_+_32224457 1.206 ENSMUST00000183121.1
Arhgap32
Rho GTPase activating protein 32
chr10_-_128498676 1.204 ENSMUST00000026428.3
Myl6b
myosin, light polypeptide 6B
chr16_+_17561885 1.193 ENSMUST00000171002.1
ENSMUST00000023441.4
P2rx6

purinergic receptor P2X, ligand-gated ion channel, 6

chr10_+_97482350 1.164 ENSMUST00000163448.2
Dcn
decorin
chr11_-_51650813 1.156 ENSMUST00000142721.1
ENSMUST00000156835.1
ENSMUST00000001080.9
N4bp3


NEDD4 binding protein 3


chr1_+_75549581 1.138 ENSMUST00000154101.1
Slc4a3
solute carrier family 4 (anion exchanger), member 3
chr8_-_60954726 1.125 ENSMUST00000110302.1
Clcn3
chloride channel 3
chr2_+_32628390 1.122 ENSMUST00000156578.1
Ak1
adenylate kinase 1
chr10_+_21993890 1.121 ENSMUST00000092673.4
Sgk1
serum/glucocorticoid regulated kinase 1
chr4_+_42459563 1.117 ENSMUST00000098119.2
Gm3883
predicted gene 3883
chr19_+_8664005 1.098 ENSMUST00000035444.3
ENSMUST00000163785.1
Chrm1

cholinergic receptor, muscarinic 1, CNS

chr11_+_78188422 1.071 ENSMUST00000002128.7
ENSMUST00000150941.1
Rab34

RAB34, member of RAS oncogene family

chr17_-_45592485 1.047 ENSMUST00000166119.1
Slc29a1
solute carrier family 29 (nucleoside transporters), member 1
chrX_-_167209149 1.043 ENSMUST00000112176.1
Tmsb4x
thymosin, beta 4, X chromosome
chr6_-_99044414 1.039 ENSMUST00000177507.1
ENSMUST00000123992.1
Foxp1

forkhead box P1

chr19_+_5447692 1.010 ENSMUST00000025850.5
Fosl1
fos-like antigen 1
chr3_+_103576081 1.004 ENSMUST00000183637.1
ENSMUST00000117221.2
ENSMUST00000118117.1
ENSMUST00000118563.2
Syt6



synaptotagmin VI



chrX_+_159840463 0.995 ENSMUST00000112451.1
ENSMUST00000112453.2
Sh3kbp1

SH3-domain kinase binding protein 1

chr17_-_45592262 0.989 ENSMUST00000164769.1
Slc29a1
solute carrier family 29 (nucleoside transporters), member 1
chr11_-_120041774 0.984 ENSMUST00000103019.1
Aatk
apoptosis-associated tyrosine kinase
chr2_-_45110336 0.975 ENSMUST00000028229.6
ENSMUST00000152232.1
Zeb2

zinc finger E-box binding homeobox 2

chr19_-_6840590 0.968 ENSMUST00000170516.2
ENSMUST00000025903.5
Rps6ka4

ribosomal protein S6 kinase, polypeptide 4

chr9_+_114978507 0.961 ENSMUST00000183104.1
Osbpl10
oxysterol binding protein-like 10
chr4_+_152008803 0.960 ENSMUST00000097773.3
Klhl21
kelch-like 21
chr18_-_37969742 0.950 ENSMUST00000166148.1
ENSMUST00000163131.1
ENSMUST00000043437.7
Fchsd1


FCH and double SH3 domains 1


chrX_-_7740206 0.948 ENSMUST00000128289.1
Ccdc120
coiled-coil domain containing 120
chr2_+_25428699 0.929 ENSMUST00000102919.3
Abca2
ATP-binding cassette, sub-family A (ABC1), member 2
chr12_+_80518990 0.922 ENSMUST00000021558.6
Galnt16
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 16
chr13_+_93304799 0.918 ENSMUST00000080127.5
Homer1
homer homolog 1 (Drosophila)
chr11_+_78188737 0.916 ENSMUST00000108322.2
Rab34
RAB34, member of RAS oncogene family
chr7_+_110772604 0.909 ENSMUST00000005829.6
Ampd3
adenosine monophosphate deaminase 3
chr9_+_50752758 0.888 ENSMUST00000034562.7
Cryab
crystallin, alpha B
chr15_+_84669565 0.883 ENSMUST00000171460.1
Prr5
proline rich 5 (renal)
chr16_+_90220742 0.882 ENSMUST00000023707.9
Sod1
superoxide dismutase 1, soluble
chr9_+_104566677 0.876 ENSMUST00000157006.1
Cpne4
copine IV
chr3_-_121283096 0.870 ENSMUST00000135818.1
ENSMUST00000137234.1
Tmem56

transmembrane protein 56

chr7_-_31126945 0.844 ENSMUST00000098548.4
Scn1b
sodium channel, voltage-gated, type I, beta
chr2_+_131909928 0.842 ENSMUST00000091288.6
Prnp
prion protein
chr7_-_127946725 0.842 ENSMUST00000118755.1
ENSMUST00000094026.3
Prss36

protease, serine, 36

chr2_-_36105271 0.828 ENSMUST00000112960.1
ENSMUST00000112967.5
ENSMUST00000112963.1
Lhx6


LIM homeobox protein 6


chr9_+_69454066 0.813 ENSMUST00000134907.1
Anxa2
annexin A2
chr18_+_61045139 0.807 ENSMUST00000025522.4
ENSMUST00000115274.1
Pdgfrb

platelet derived growth factor receptor, beta polypeptide

chr2_-_25224653 0.807 ENSMUST00000043584.4
Tubb4b
tubulin, beta 4B class IVB
chr2_+_131909951 0.799 ENSMUST00000124100.1
ENSMUST00000136783.1
PRND

prion protein gene complex (Prn), transcript variant 1, mRNA

chr5_+_35278566 0.796 ENSMUST00000049545.5
Adra2c
adrenergic receptor, alpha 2c
chr9_+_32224246 0.794 ENSMUST00000168954.2
Arhgap32
Rho GTPase activating protein 32
chr11_-_3914664 0.792 ENSMUST00000109995.1
ENSMUST00000051207.1
Slc35e4

solute carrier family 35, member E4

chr11_+_78188806 0.792 ENSMUST00000056241.5
Rab34
RAB34, member of RAS oncogene family
chr5_+_117363513 0.780 ENSMUST00000111959.1
Wsb2
WD repeat and SOCS box-containing 2
chr1_+_87327008 0.776 ENSMUST00000172794.1
ENSMUST00000164992.2
Gigyf2

GRB10 interacting GYF protein 2

chr15_+_54571358 0.769 ENSMUST00000025356.2
Mal2
mal, T cell differentiation protein 2
chr8_-_11008458 0.763 ENSMUST00000040514.6
Irs2
insulin receptor substrate 2
chr1_+_87327044 0.748 ENSMUST00000173173.1
Gigyf2
GRB10 interacting GYF protein 2
chr7_+_120917744 0.744 ENSMUST00000033173.7
ENSMUST00000106483.2
Polr3e

polymerase (RNA) III (DNA directed) polypeptide E

chr17_-_47834682 0.744 ENSMUST00000066368.6
Mdfi
MyoD family inhibitor
chr4_+_123183456 0.740 ENSMUST00000126995.1
Hpcal4
hippocalcin-like 4
chr7_-_113347273 0.734 ENSMUST00000117577.1
Btbd10
BTB (POZ) domain containing 10
chr17_+_35841491 0.732 ENSMUST00000082337.6
Mdc1
mediator of DNA damage checkpoint 1
chr2_+_136713444 0.713 ENSMUST00000028727.4
ENSMUST00000110098.3
Snap25

synaptosomal-associated protein 25

chr10_-_76725978 0.709 ENSMUST00000001147.4
Col6a1
collagen, type VI, alpha 1
chr4_+_42714926 0.705 ENSMUST00000178454.1
Gm21955
predicted gene, 21955
chr9_+_69453620 0.702 ENSMUST00000034756.8
ENSMUST00000123470.1
Anxa2

annexin A2

chr4_-_6454068 0.702 ENSMUST00000124344.1
Nsmaf
neutral sphingomyelinase (N-SMase) activation associated factor
chr9_-_116175318 0.700 ENSMUST00000061101.4
ENSMUST00000035014.6
Tgfbr2

transforming growth factor, beta receptor II

chr4_+_42158092 0.694 ENSMUST00000098122.2
Gm13306
predicted gene 13306
chr16_-_4880284 0.688 ENSMUST00000037843.6
Ubald1
UBA-like domain containing 1
chr13_+_93303757 0.681 ENSMUST00000109494.1
Homer1
homer homolog 1 (Drosophila)
chr11_+_87592145 0.669 ENSMUST00000103179.3
ENSMUST00000092802.5
ENSMUST00000146871.1
Mtmr4


myotubularin related protein 4


chr11_+_120467635 0.669 ENSMUST00000140862.1
ENSMUST00000106205.1
ENSMUST00000106203.1
ENSMUST00000026900.7
Hgs



HGF-regulated tyrosine kinase substrate



chr11_+_75655873 0.661 ENSMUST00000108431.2
Myo1c
myosin IC
chr14_+_76476913 0.653 ENSMUST00000140251.2
Tsc22d1
TSC22 domain family, member 1
chr13_-_56296551 0.648 ENSMUST00000021970.9
Cxcl14
chemokine (C-X-C motif) ligand 14
chr6_+_86849488 0.644 ENSMUST00000089519.6
ENSMUST00000113668.1
Aak1

AP2 associated kinase 1

chr7_+_19181159 0.642 ENSMUST00000120595.1
ENSMUST00000048502.8
Eml2

echinoderm microtubule associated protein like 2

chr1_-_6215292 0.639 ENSMUST00000097832.1
4732440D04Rik
RIKEN cDNA 4732440D04 gene
chr13_+_30659999 0.639 ENSMUST00000091672.6
ENSMUST00000110310.1
ENSMUST00000095914.5
Dusp22


dual specificity phosphatase 22


chr6_-_97459279 0.636 ENSMUST00000113359.1
Frmd4b
FERM domain containing 4B
chr1_-_132390301 0.621 ENSMUST00000132435.1
Tmcc2
transmembrane and coiled-coil domains 2
chr6_-_56901870 0.620 ENSMUST00000101367.2
Nt5c3
5'-nucleotidase, cytosolic III
chr9_-_78480736 0.613 ENSMUST00000156988.1
Eef1a1
eukaryotic translation elongation factor 1 alpha 1
chr7_+_144284385 0.600 ENSMUST00000097929.2
Shank2
SH3/ankyrin domain gene 2
chr15_+_82275197 0.575 ENSMUST00000116423.1
Sept3
septin 3
chr1_-_37536232 0.570 ENSMUST00000042161.8
Mgat4a
mannoside acetylglucosaminyltransferase 4, isoenzyme A
chr14_-_79301623 0.570 ENSMUST00000022595.7
Rgcc
regulator of cell cycle
chr10_-_83337440 0.563 ENSMUST00000126617.1
Slc41a2
solute carrier family 41, member 2
chr14_-_68124836 0.559 ENSMUST00000111089.1
ENSMUST00000022638.5
Nefm

neurofilament, medium polypeptide

chr1_+_33908172 0.544 ENSMUST00000182513.1
ENSMUST00000183034.1
Dst

dystonin

chr5_+_105415738 0.537 ENSMUST00000112707.1
Lrrc8b
leucine rich repeat containing 8 family, member B
chr4_-_6454262 0.528 ENSMUST00000029910.5
Nsmaf
neutral sphingomyelinase (N-SMase) activation associated factor
chr2_-_29253001 0.522 ENSMUST00000071201.4
Ntng2
netrin G2
chr5_-_92348871 0.516 ENSMUST00000038816.6
ENSMUST00000118006.1
Cxcl10

chemokine (C-X-C motif) ligand 10

chr6_+_135362931 0.515 ENSMUST00000032330.9
Emp1
epithelial membrane protein 1
chr14_-_31417666 0.513 ENSMUST00000100730.3
Sh3bp5
SH3-domain binding protein 5 (BTK-associated)
chr2_-_102400863 0.507 ENSMUST00000102573.1
Trim44
tripartite motif-containing 44
chr18_+_40258361 0.499 ENSMUST00000091927.4
Kctd16
potassium channel tetramerisation domain containing 16
chr6_-_122856151 0.495 ENSMUST00000042081.8
C3ar1
complement component 3a receptor 1
chr8_-_105966038 0.489 ENSMUST00000116429.2
ENSMUST00000034370.9
Slc12a4

solute carrier family 12, member 4

chr5_+_25247344 0.485 ENSMUST00000114950.1
Galnt11
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 11
chr9_-_109059711 0.479 ENSMUST00000061973.4
Trex1
three prime repair exonuclease 1
chr7_+_66365905 0.476 ENSMUST00000107486.1
Gm10974
predicted gene 10974
chr11_-_76509419 0.470 ENSMUST00000094012.4
Abr
active BCR-related gene
chr4_-_149126688 0.450 ENSMUST00000030815.2
Cort
cortistatin
chr1_-_182517447 0.446 ENSMUST00000068505.8
Capn2
calpain 2
chr2_-_76215363 0.444 ENSMUST00000144892.1
Pde11a
phosphodiesterase 11A
chr15_+_82274935 0.427 ENSMUST00000023095.6
Sept3
septin 3
chr1_+_165461037 0.418 ENSMUST00000027853.5
Mpc2
mitochondrial pyruvate carrier 2
chr4_+_126148457 0.414 ENSMUST00000106150.2
Eva1b
eva-1 homolog B (C. elegans)
chr5_+_105732063 0.413 ENSMUST00000154807.1
Lrrc8d
leucine rich repeat containing 8D
chr16_+_29209695 0.401 ENSMUST00000089824.4
Hrasls
HRAS-like suppressor
chr15_-_64312636 0.399 ENSMUST00000177083.1
ENSMUST00000177371.1
Asap1

ArfGAP with SH3 domain, ankyrin repeat and PH domain1

chr15_+_77084367 0.397 ENSMUST00000181870.1
1700109K24Rik
RIKEN cDNA 1700109K24 gene
chr4_-_140648736 0.384 ENSMUST00000039204.3
ENSMUST00000105799.1
ENSMUST00000097820.2
Arhgef10l


Rho guanine nucleotide exchange factor (GEF) 10-like


chr16_+_78930940 0.382 ENSMUST00000114216.1
ENSMUST00000069148.6
ENSMUST00000023568.7
Chodl


chondrolectin


chrX_+_73675500 0.382 ENSMUST00000171398.1
Slc6a8
solute carrier family 6 (neurotransmitter transporter, creatine), member 8
chr11_-_120467414 0.379 ENSMUST00000076921.6
Arl16
ADP-ribosylation factor-like 16
chr1_+_64690443 0.370 ENSMUST00000114077.1
Ccnyl1
cyclin Y-like 1
chr8_-_8639363 0.368 ENSMUST00000152698.1
Efnb2
ephrin B2
chr18_-_31317043 0.366 ENSMUST00000139924.1
ENSMUST00000153060.1
Rit2

Ras-like without CAAX 2

chr11_-_79059872 0.360 ENSMUST00000141409.1
Ksr1
kinase suppressor of ras 1
chr19_-_32196393 0.360 ENSMUST00000151822.1
Sgms1
sphingomyelin synthase 1
chr7_-_29248375 0.353 ENSMUST00000032808.4
2200002D01Rik
RIKEN cDNA 2200002D01 gene
chrX_+_7722214 0.350 ENSMUST00000043045.2
ENSMUST00000116634.1
ENSMUST00000115689.3
ENSMUST00000131077.1
ENSMUST00000115688.1
ENSMUST00000116633.1
Wdr45





WD repeat domain 45





chr18_+_36559972 0.332 ENSMUST00000134146.1
Ankhd1
ankyrin repeat and KH domain containing 1
chr2_+_91257323 0.327 ENSMUST00000111349.2
ENSMUST00000131711.1
Pacsin3

protein kinase C and casein kinase substrate in neurons 3

chr1_+_75546258 0.326 ENSMUST00000124341.1
Slc4a3
solute carrier family 4 (anion exchanger), member 3
chr2_+_164948219 0.323 ENSMUST00000017881.2
Mmp9
matrix metallopeptidase 9
chr3_+_96601084 0.320 ENSMUST00000062058.3
Lix1l
Lix1-like
chr5_+_105731755 0.311 ENSMUST00000127686.1
Lrrc8d
leucine rich repeat containing 8D
chr7_-_80401707 0.309 ENSMUST00000120753.1
Furin
furin (paired basic amino acid cleaving enzyme)
chr19_-_7483241 0.308 ENSMUST00000025667.6
ENSMUST00000065304.5
ENSMUST00000088171.4
Rtn3


reticulon 3


chr12_+_31265279 0.306 ENSMUST00000002979.8
ENSMUST00000170495.1
Lamb1

laminin B1

chr7_-_45920830 0.301 ENSMUST00000164119.1
Emp3
epithelial membrane protein 3
chr19_-_32210969 0.300 ENSMUST00000151289.1
Sgms1
sphingomyelin synthase 1
chr2_-_25461021 0.292 ENSMUST00000151239.1
BC029214
cDNA sequence BC029214
chr10_+_128411616 0.287 ENSMUST00000096386.5
ENSMUST00000171342.1
Rnf41

ring finger protein 41

chr19_-_46338632 0.285 ENSMUST00000051234.8
ENSMUST00000167861.1
Cuedc2

CUE domain containing 2

chr17_-_30612613 0.282 ENSMUST00000167624.1
ENSMUST00000024823.6
Glo1

glyoxalase 1

chr11_-_115708538 0.278 ENSMUST00000106495.1
ENSMUST00000021090.7
Grb2

growth factor receptor bound protein 2

chr3_+_62338344 0.276 ENSMUST00000079300.6
Arhgef26
Rho guanine nucleotide exchange factor (GEF) 26
chr8_+_69822429 0.272 ENSMUST00000164890.1
ENSMUST00000034325.4
Lpar2

lysophosphatidic acid receptor 2

chr1_+_181150926 0.270 ENSMUST00000134115.1
ENSMUST00000111059.1
Cnih4

cornichon homolog 4 (Drosophila)

chr1_+_87326997 0.265 ENSMUST00000027475.8
Gigyf2
GRB10 interacting GYF protein 2
chr10_+_80930071 0.264 ENSMUST00000015456.8
Gadd45b
growth arrest and DNA-damage-inducible 45 beta
chr11_-_97150025 0.263 ENSMUST00000118375.1
Tbkbp1
TBK1 binding protein 1
chr1_+_82839449 0.262 ENSMUST00000113444.1
ENSMUST00000063380.4
Agfg1

ArfGAP with FG repeats 1

chr19_-_7483212 0.258 ENSMUST00000088169.5
Rtn3
reticulon 3
chr16_+_33062512 0.257 ENSMUST00000023497.2
Lmln
leishmanolysin-like (metallopeptidase M8 family)
chr14_-_36968679 0.256 ENSMUST00000067700.6
Ccser2
coiled-coil serine rich 2

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
1.3 9.4 GO:0070494 regulation of thrombin receptor signaling pathway(GO:0070494) negative regulation of thrombin receptor signaling pathway(GO:0070495)
1.0 4.0 GO:0003430 growth plate cartilage chondrocyte growth(GO:0003430)
0.7 10.3 GO:1902004 positive regulation of beta-amyloid formation(GO:1902004)
0.7 3.3 GO:0030951 establishment or maintenance of microtubule cytoskeleton polarity(GO:0030951)
0.6 1.8 GO:0032241 positive regulation of nucleobase-containing compound transport(GO:0032241) regulation of nucleoside transport(GO:0032242) negative regulation of circadian sleep/wake cycle, non-REM sleep(GO:0042323) negative regulation of mucus secretion(GO:0070256)
0.6 2.8 GO:1905169 protein localization to phagocytic vesicle(GO:1905161) regulation of protein localization to phagocytic vesicle(GO:1905169) positive regulation of protein localization to phagocytic vesicle(GO:1905171)
0.5 3.3 GO:1903056 positive regulation of lens fiber cell differentiation(GO:1902748) regulation of melanosome organization(GO:1903056)
0.5 2.7 GO:0048133 germ-line stem cell division(GO:0042078) male germ-line stem cell asymmetric division(GO:0048133) germline stem cell asymmetric division(GO:0098728)
0.4 1.3 GO:0061153 trachea submucosa development(GO:0061152) trachea gland development(GO:0061153)
0.4 1.1 GO:0097401 synaptic vesicle lumen acidification(GO:0097401)
0.3 2.0 GO:0032804 negative regulation of low-density lipoprotein particle receptor catabolic process(GO:0032804)
0.3 1.0 GO:0060478 acrosomal vesicle exocytosis(GO:0060478)
0.3 1.0 GO:0043988 histone H3-S28 phosphorylation(GO:0043988)
0.3 3.8 GO:0051152 positive regulation of smooth muscle cell differentiation(GO:0051152)
0.3 1.6 GO:1902031 regulation of NADP metabolic process(GO:1902031)
0.3 1.2 GO:0038128 ERBB2 signaling pathway(GO:0038128)
0.3 2.0 GO:0015862 uridine transport(GO:0015862)
0.3 0.8 GO:0086047 membrane depolarization during Purkinje myocyte cell action potential(GO:0086047)
0.3 0.8 GO:1902938 regulation of intracellular calcium activated chloride channel activity(GO:1902938)
0.3 0.8 GO:0035441 cell migration involved in vasculogenesis(GO:0035441) metanephric glomerular mesangium development(GO:0072223) metanephric glomerular mesangial cell proliferation involved in metanephros development(GO:0072262)
0.2 1.1 GO:0007197 adenylate cyclase-inhibiting G-protein coupled acetylcholine receptor signaling pathway(GO:0007197) phospholipase C-activating G-protein coupled acetylcholine receptor signaling pathway(GO:0007207)
0.2 1.7 GO:0033564 anterior/posterior axon guidance(GO:0033564)
0.2 0.6 GO:2000501 natural killer cell chemotaxis(GO:0035747) regulation of natural killer cell chemotaxis(GO:2000501)
0.2 2.9 GO:0043011 myeloid dendritic cell differentiation(GO:0043011)
0.2 8.0 GO:0045746 negative regulation of Notch signaling pathway(GO:0045746)
0.2 0.8 GO:0035624 receptor transactivation(GO:0035624) epidermal growth factor-activated receptor transactivation by G-protein coupled receptor signaling pathway(GO:0035625)
0.2 0.2 GO:0030862 positive regulation of polarized epithelial cell differentiation(GO:0030862)
0.2 1.1 GO:0046103 ADP biosynthetic process(GO:0006172) inosine biosynthetic process(GO:0046103)
0.2 0.6 GO:0045110 intermediate filament bundle assembly(GO:0045110)
0.2 0.5 GO:1901509 regulation of endothelial tube morphogenesis(GO:1901509)
0.2 0.2 GO:1903422 negative regulation of synaptic vesicle recycling(GO:1903422)
0.2 1.2 GO:0032261 purine nucleotide salvage(GO:0032261) IMP salvage(GO:0032264)
0.2 0.5 GO:0002430 complement receptor mediated signaling pathway(GO:0002430)
0.2 0.8 GO:0031580 membrane raft polarization(GO:0001766) membrane raft distribution(GO:0031580)
0.1 0.9 GO:0007021 tubulin complex assembly(GO:0007021)
0.1 1.9 GO:2001135 regulation of endocytic recycling(GO:2001135)
0.1 1.0 GO:0007296 vitellogenesis(GO:0007296)
0.1 0.6 GO:2000048 negative regulation of cell-cell adhesion mediated by cadherin(GO:2000048)
0.1 0.8 GO:1904936 cerebral cortex GABAergic interneuron migration(GO:0021853) interneuron migration(GO:1904936)
0.1 1.0 GO:1900747 negative regulation of vascular endothelial growth factor signaling pathway(GO:1900747) negative regulation of cellular response to vascular endothelial growth factor stimulus(GO:1902548)
0.1 1.5 GO:1901621 negative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning(GO:1901621)
0.1 0.4 GO:0046032 ADP catabolic process(GO:0046032)
0.1 0.9 GO:0032380 regulation of intracellular lipid transport(GO:0032377) regulation of intracellular sterol transport(GO:0032380) regulation of intracellular cholesterol transport(GO:0032383)
0.1 0.7 GO:1900748 positive regulation of vascular endothelial growth factor signaling pathway(GO:1900748)
0.1 0.5 GO:0021812 neuronal-glial interaction involved in cerebral cortex radial glia guided migration(GO:0021812)
0.1 1.8 GO:2001256 regulation of store-operated calcium entry(GO:2001256)
0.1 0.9 GO:0060087 relaxation of vascular smooth muscle(GO:0060087)
0.1 1.2 GO:0030049 muscle filament sliding(GO:0030049)
0.1 0.9 GO:0098967 exocytic insertion of neurotransmitter receptor to plasma membrane(GO:0098881) exocytic insertion of neurotransmitter receptor to postsynaptic membrane(GO:0098967)
0.1 0.4 GO:1901475 pyruvate transmembrane transport(GO:1901475)
0.1 1.0 GO:0032625 interleukin-21 production(GO:0032625) interleukin-21 secretion(GO:0072619)
0.1 1.4 GO:0061469 regulation of type B pancreatic cell proliferation(GO:0061469)
0.1 0.8 GO:0002903 negative regulation of B cell apoptotic process(GO:0002903)
0.1 0.3 GO:0010936 negative regulation of macrophage cytokine production(GO:0010936)
0.1 0.6 GO:0071787 endoplasmic reticulum tubular network assembly(GO:0071787)
0.1 0.5 GO:0043314 negative regulation of neutrophil degranulation(GO:0043314) negative regulation of blood vessel remodeling(GO:0060313)
0.1 0.6 GO:0010968 regulation of microtubule nucleation(GO:0010968)
0.1 1.0 GO:0032482 Rab protein signal transduction(GO:0032482)
0.1 0.6 GO:0046085 adenosine metabolic process(GO:0046085)
0.1 0.3 GO:1900122 positive regulation of receptor binding(GO:1900122)
0.1 1.1 GO:0043402 glucocorticoid mediated signaling pathway(GO:0043402)
0.1 0.6 GO:0002710 negative regulation of T cell mediated immunity(GO:0002710)
0.1 0.4 GO:1903527 positive regulation of membrane tubulation(GO:1903527)
0.1 0.2 GO:0071544 diphosphoinositol polyphosphate catabolic process(GO:0071544)
0.1 0.7 GO:0038203 TORC2 signaling(GO:0038203)
0.1 1.5 GO:0014067 negative regulation of phosphatidylinositol 3-kinase signaling(GO:0014067)
0.1 0.4 GO:0016540 protein autoprocessing(GO:0016540)
0.1 0.7 GO:0006686 sphingomyelin biosynthetic process(GO:0006686)
0.1 0.4 GO:0032489 regulation of Cdc42 protein signal transduction(GO:0032489)
0.1 0.5 GO:0018243 protein O-linked glycosylation via threonine(GO:0018243)
0.1 0.3 GO:0035617 stress granule disassembly(GO:0035617)
0.1 2.5 GO:0021952 central nervous system projection neuron axonogenesis(GO:0021952)
0.1 1.8 GO:0031571 mitotic G1 DNA damage checkpoint(GO:0031571)
0.1 0.6 GO:0010839 negative regulation of keratinocyte proliferation(GO:0010839)
0.1 0.2 GO:1902340 telomeric heterochromatin assembly(GO:0031509) negative regulation of chromosome condensation(GO:1902340)
0.1 0.3 GO:1901525 negative regulation of macromitophagy(GO:1901525)
0.1 4.3 GO:0072583 clathrin-mediated endocytosis(GO:0072583)
0.1 1.0 GO:0007274 neuromuscular synaptic transmission(GO:0007274)
0.0 0.3 GO:0009098 branched-chain amino acid biosynthetic process(GO:0009082) leucine biosynthetic process(GO:0009098) valine biosynthetic process(GO:0009099)
0.0 0.7 GO:0044342 type B pancreatic cell proliferation(GO:0044342)
0.0 1.2 GO:0033198 response to ATP(GO:0033198)
0.0 3.0 GO:0045806 negative regulation of endocytosis(GO:0045806)
0.0 0.8 GO:0032060 bleb assembly(GO:0032060)
0.0 0.4 GO:0019243 methylglyoxal catabolic process to D-lactate via S-lactoyl-glutathione(GO:0019243) methylglyoxal catabolic process(GO:0051596) methylglyoxal catabolic process to lactate(GO:0061727)
0.0 0.7 GO:0060707 trophoblast giant cell differentiation(GO:0060707)
0.0 0.2 GO:2000774 positive regulation of cellular senescence(GO:2000774)
0.0 0.3 GO:0000185 activation of MAPKKK activity(GO:0000185)
0.0 0.6 GO:0044804 nucleophagy(GO:0044804)
0.0 0.2 GO:0006538 glutamate catabolic process(GO:0006538)
0.0 2.0 GO:0010501 RNA secondary structure unwinding(GO:0010501)
0.0 0.2 GO:0006646 phosphatidylethanolamine biosynthetic process(GO:0006646)
0.0 0.7 GO:0006622 protein targeting to lysosome(GO:0006622) regulation of exosomal secretion(GO:1903541) positive regulation of exosomal secretion(GO:1903543)
0.0 0.5 GO:0008090 retrograde axonal transport(GO:0008090)
0.0 0.2 GO:0035726 common myeloid progenitor cell proliferation(GO:0035726)
0.0 0.2 GO:0036265 RNA (guanine-N7)-methylation(GO:0036265)
0.0 0.4 GO:0046485 ether lipid metabolic process(GO:0046485)
0.0 0.7 GO:0070208 protein heterotrimerization(GO:0070208)
0.0 0.1 GO:0003100 regulation of systemic arterial blood pressure by endothelin(GO:0003100)
0.0 0.1 GO:0038032 termination of G-protein coupled receptor signaling pathway(GO:0038032)
0.0 0.6 GO:0051968 positive regulation of synaptic transmission, glutamatergic(GO:0051968)
0.0 0.4 GO:0046069 cGMP catabolic process(GO:0046069)
0.0 3.2 GO:0010811 positive regulation of cell-substrate adhesion(GO:0010811)
0.0 0.3 GO:0001675 acrosome assembly(GO:0001675)
0.0 0.1 GO:0060715 syncytiotrophoblast cell differentiation involved in labyrinthine layer development(GO:0060715)
0.0 0.3 GO:0060670 branching involved in labyrinthine layer morphogenesis(GO:0060670)
0.0 0.2 GO:0071285 response to lithium ion(GO:0010226) cellular response to lithium ion(GO:0071285)
0.0 0.1 GO:1900029 positive regulation of ruffle assembly(GO:1900029)
0.0 0.6 GO:0071364 cellular response to epidermal growth factor stimulus(GO:0071364)
0.0 0.5 GO:0007193 adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway(GO:0007193)
0.0 0.2 GO:0046051 UTP biosynthetic process(GO:0006228) UTP metabolic process(GO:0046051)
0.0 1.0 GO:0032465 regulation of cytokinesis(GO:0032465)
0.0 0.1 GO:0016584 nucleosome positioning(GO:0016584)
0.0 0.1 GO:0072344 rescue of stalled ribosome(GO:0072344)
0.0 0.5 GO:0061099 negative regulation of protein tyrosine kinase activity(GO:0061099)
0.0 0.3 GO:0001886 endothelial cell morphogenesis(GO:0001886)
0.0 0.1 GO:1903800 regulation of Golgi inheritance(GO:0090170) positive regulation of production of miRNAs involved in gene silencing by miRNA(GO:1903800)
0.0 0.1 GO:0050774 negative regulation of dendrite morphogenesis(GO:0050774)
0.0 0.2 GO:0090073 positive regulation of protein homodimerization activity(GO:0090073)
0.0 0.5 GO:0035458 cellular response to interferon-beta(GO:0035458)
0.0 0.4 GO:0072337 modified amino acid transport(GO:0072337)
0.0 0.2 GO:0031998 regulation of fatty acid beta-oxidation(GO:0031998)
0.0 0.3 GO:0032933 response to sterol depletion(GO:0006991) SREBP signaling pathway(GO:0032933) cellular response to sterol depletion(GO:0071501)
0.0 0.9 GO:0030641 regulation of cellular pH(GO:0030641)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 4.0 GO:0034366 spherical high-density lipoprotein particle(GO:0034366)
0.5 1.5 GO:1990667 PCSK9-AnxA2 complex(GO:1990667)
0.5 3.3 GO:0005638 lamin filament(GO:0005638)
0.3 3.7 GO:0030130 clathrin coat of trans-Golgi network vesicle(GO:0030130)
0.3 2.8 GO:0000015 phosphopyruvate hydratase complex(GO:0000015)
0.3 1.0 GO:0099569 presynaptic cytoskeleton(GO:0099569)
0.2 0.7 GO:0045160 myosin I complex(GO:0045160)
0.2 0.2 GO:1990796 photoreceptor cell terminal bouton(GO:1990796)
0.2 0.7 GO:0070032 synaptobrevin 2-SNAP-25-syntaxin-1a-complexin I complex(GO:0070032) synaptobrevin 2-SNAP-25-syntaxin-1a-complexin II complex(GO:0070033)
0.1 9.9 GO:0009925 basal plasma membrane(GO:0009925)
0.1 0.9 GO:0097512 cardiac myofibril(GO:0097512)
0.1 1.2 GO:0005883 neurofilament(GO:0005883)
0.1 1.1 GO:0001520 outer dense fiber(GO:0001520)
0.1 1.0 GO:0005827 polar microtubule(GO:0005827)
0.1 2.9 GO:0032279 asymmetric synapse(GO:0032279)
0.1 0.5 GO:0031673 H zone(GO:0031673)
0.1 1.2 GO:0016461 unconventional myosin complex(GO:0016461)
0.1 0.5 GO:0043259 laminin-1 complex(GO:0005606) laminin-10 complex(GO:0043259)
0.1 1.8 GO:1990635 proximal dendrite(GO:1990635)
0.1 0.6 GO:0071439 clathrin complex(GO:0071439)
0.1 0.5 GO:0012510 trans-Golgi network transport vesicle membrane(GO:0012510)
0.1 0.4 GO:0097447 dendritic tree(GO:0097447)
0.1 1.1 GO:0042581 specific granule(GO:0042581)
0.1 0.8 GO:0045298 tubulin complex(GO:0045298)
0.1 1.2 GO:0031229 integral component of nuclear inner membrane(GO:0005639) intrinsic component of nuclear inner membrane(GO:0031229)
0.1 5.7 GO:0042734 presynaptic membrane(GO:0042734)
0.1 2.8 GO:0032281 AMPA glutamate receptor complex(GO:0032281)
0.1 1.4 GO:0043235 receptor complex(GO:0043235)
0.1 0.3 GO:0070436 Grb2-EGFR complex(GO:0070436)
0.1 0.9 GO:0031045 dense core granule(GO:0031045)
0.1 0.7 GO:0000138 Golgi trans cisterna(GO:0000138)
0.1 1.2 GO:0098644 complex of collagen trimers(GO:0098644)
0.1 1.4 GO:0097038 perinuclear endoplasmic reticulum(GO:0097038)
0.1 0.8 GO:0001518 voltage-gated sodium channel complex(GO:0001518)
0.1 2.9 GO:0031985 Golgi cisterna(GO:0031985)
0.0 1.7 GO:0043034 costamere(GO:0043034)
0.0 1.7 GO:0032809 neuronal cell body membrane(GO:0032809)
0.0 2.1 GO:0005581 collagen trimer(GO:0005581)
0.0 3.4 GO:0005604 basement membrane(GO:0005604)
0.0 0.0 GO:0036056 filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057)
0.0 0.4 GO:0005641 nuclear envelope lumen(GO:0005641)
0.0 0.2 GO:0043527 tRNA methyltransferase complex(GO:0043527)
0.0 0.7 GO:0031932 TORC2 complex(GO:0031932)
0.0 6.3 GO:0001650 fibrillar center(GO:0001650)
0.0 9.2 GO:0016324 apical plasma membrane(GO:0016324)
0.0 0.7 GO:0005666 DNA-directed RNA polymerase III complex(GO:0005666)
0.0 0.5 GO:0034045 pre-autophagosomal structure membrane(GO:0034045)
0.0 0.2 GO:0044294 dendritic growth cone(GO:0044294)
0.0 3.0 GO:0055037 recycling endosome(GO:0055037)
0.0 0.5 GO:0046658 anchored component of plasma membrane(GO:0046658)
0.0 2.6 GO:0045211 postsynaptic membrane(GO:0045211)
0.0 0.3 GO:0035253 ciliary rootlet(GO:0035253)
0.0 0.2 GO:0036038 MKS complex(GO:0036038)
0.0 0.1 GO:0016593 Cdc73/Paf1 complex(GO:0016593)
0.0 0.3 GO:0071782 endoplasmic reticulum tubular network(GO:0071782)
0.0 3.3 GO:0014069 postsynaptic density(GO:0014069)
0.0 0.2 GO:0008250 oligosaccharyltransferase complex(GO:0008250)
0.0 2.9 GO:0031253 cell projection membrane(GO:0031253)
0.0 0.4 GO:0031305 integral component of mitochondrial inner membrane(GO:0031305)
0.0 0.1 GO:0031462 Cul2-RING ubiquitin ligase complex(GO:0031462)
0.0 0.3 GO:0005811 lipid particle(GO:0005811)
0.0 0.2 GO:0000407 pre-autophagosomal structure(GO:0000407)
0.0 0.9 GO:0030139 endocytic vesicle(GO:0030139)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
2.4 9.4 GO:0005008 hepatocyte growth factor-activated receptor activity(GO:0005008)
0.5 1.6 GO:0004473 malic enzyme activity(GO:0004470) malate dehydrogenase (decarboxylating) (NAD+) activity(GO:0004471) malate dehydrogenase (decarboxylating) (NADP+) activity(GO:0004473)
0.4 1.5 GO:0004859 phospholipase inhibitor activity(GO:0004859) phospholipase A2 inhibitor activity(GO:0019834)
0.3 2.8 GO:0004634 phosphopyruvate hydratase activity(GO:0004634)
0.3 3.7 GO:0032050 clathrin heavy chain binding(GO:0032050)
0.3 1.2 GO:0016230 sphingomyelin phosphodiesterase activator activity(GO:0016230)
0.3 1.7 GO:0005042 netrin receptor activity(GO:0005042)
0.3 1.1 GO:0072320 volume-sensitive chloride channel activity(GO:0072320)
0.3 3.3 GO:0009931 calcium-dependent protein serine/threonine kinase activity(GO:0009931)
0.3 0.8 GO:0051379 epinephrine binding(GO:0051379)
0.3 2.7 GO:0031802 type 5 metabotropic glutamate receptor binding(GO:0031802)
0.3 1.8 GO:0001609 G-protein coupled adenosine receptor activity(GO:0001609)
0.2 0.9 GO:0004784 superoxide dismutase activity(GO:0004784) oxidoreductase activity, acting on superoxide radicals as acceptor(GO:0016721)
0.2 1.1 GO:0016907 G-protein coupled acetylcholine receptor activity(GO:0016907)
0.2 8.0 GO:0001106 RNA polymerase II transcription corepressor activity(GO:0001106)
0.2 1.2 GO:0035381 extracellular ATP-gated cation channel activity(GO:0004931) ATP-gated ion channel activity(GO:0035381)
0.2 0.7 GO:0034714 type III transforming growth factor beta receptor binding(GO:0034714)
0.2 5.3 GO:0042805 actinin binding(GO:0042805)
0.2 4.0 GO:0051787 misfolded protein binding(GO:0051787)
0.2 3.3 GO:0003708 retinoic acid receptor activity(GO:0003708)
0.2 1.2 GO:0003876 AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
0.2 0.5 GO:0004875 complement receptor activity(GO:0004875)
0.2 3.7 GO:0017160 Ral GTPase binding(GO:0017160)
0.2 0.8 GO:0038085 vascular endothelial growth factor binding(GO:0038085)
0.2 0.6 GO:0008853 exodeoxyribonuclease III activity(GO:0008853)
0.1 1.1 GO:0043423 3-phosphoinositide-dependent protein kinase binding(GO:0043423)
0.1 0.7 GO:0033188 sphingomyelin synthase activity(GO:0033188) ceramide cholinephosphotransferase activity(GO:0047493)
0.1 2.0 GO:0008253 5'-nucleotidase activity(GO:0008253)
0.1 0.8 GO:0086006 voltage-gated sodium channel activity involved in cardiac muscle cell action potential(GO:0086006)
0.1 3.3 GO:0017075 syntaxin-1 binding(GO:0017075)
0.1 0.6 GO:0008454 alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity(GO:0008454)
0.1 3.3 GO:0008157 protein phosphatase 1 binding(GO:0008157)
0.1 0.4 GO:0050833 pyruvate transmembrane transporter activity(GO:0050833)
0.1 0.5 GO:0048248 CXCR3 chemokine receptor binding(GO:0048248)
0.1 1.1 GO:0004017 adenylate kinase activity(GO:0004017)
0.1 3.9 GO:0070412 R-SMAD binding(GO:0070412)
0.1 0.8 GO:0019911 structural constituent of myelin sheath(GO:0019911)
0.1 0.4 GO:0015220 choline transmembrane transporter activity(GO:0015220)
0.1 1.8 GO:0030215 semaphorin receptor binding(GO:0030215)
0.1 1.6 GO:0050811 GABA receptor binding(GO:0050811)
0.1 0.8 GO:0005225 volume-sensitive anion channel activity(GO:0005225)
0.1 2.0 GO:0005337 nucleoside transmembrane transporter activity(GO:0005337)
0.1 1.4 GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
0.1 0.2 GO:0008176 tRNA (guanine-N7-)-methyltransferase activity(GO:0008176)
0.1 0.5 GO:0015379 potassium:chloride symporter activity(GO:0015379) potassium ion symporter activity(GO:0022820)
0.1 7.9 GO:0004860 protein kinase inhibitor activity(GO:0004860)
0.1 1.8 GO:0070064 proline-rich region binding(GO:0070064)
0.1 0.5 GO:0043208 glycosphingolipid binding(GO:0043208)
0.1 0.4 GO:0004118 cGMP-stimulated cyclic-nucleotide phosphodiesterase activity(GO:0004118)
0.1 0.6 GO:0015643 toxic substance binding(GO:0015643)
0.1 1.5 GO:0050750 low-density lipoprotein particle receptor binding(GO:0050750)
0.1 0.7 GO:0048407 platelet-derived growth factor binding(GO:0048407)
0.1 2.2 GO:0001786 phosphatidylserine binding(GO:0001786)
0.0 0.4 GO:0047631 adenosine-diphosphatase activity(GO:0043262) ADP-ribose diphosphatase activity(GO:0047631)
0.0 0.3 GO:0052654 branched-chain-amino-acid transaminase activity(GO:0004084) L-leucine transaminase activity(GO:0052654) L-valine transaminase activity(GO:0052655) L-isoleucine transaminase activity(GO:0052656)
0.0 0.5 GO:0048406 nerve growth factor binding(GO:0048406)
0.0 0.1 GO:1990450 linear polyubiquitin binding(GO:1990450)
0.0 1.4 GO:1990841 promoter-specific chromatin binding(GO:1990841)
0.0 0.2 GO:0004305 ethanolamine kinase activity(GO:0004305)
0.0 1.2 GO:0008307 structural constituent of muscle(GO:0008307)
0.0 0.6 GO:0035612 AP-2 adaptor complex binding(GO:0035612)
0.0 0.5 GO:0004550 nucleoside diphosphate kinase activity(GO:0004550)
0.0 1.0 GO:0003785 actin monomer binding(GO:0003785)
0.0 1.0 GO:0005164 tumor necrosis factor receptor binding(GO:0005164)
0.0 0.2 GO:0004565 beta-galactosidase activity(GO:0004565)
0.0 0.7 GO:0001056 RNA polymerase III activity(GO:0001056)
0.0 0.7 GO:0008510 sodium:bicarbonate symporter activity(GO:0008510)
0.0 0.3 GO:0016846 carbon-sulfur lyase activity(GO:0016846)
0.0 0.3 GO:0031730 CCR5 chemokine receptor binding(GO:0031730)
0.0 0.1 GO:0031800 type 3 metabotropic glutamate receptor binding(GO:0031800)
0.0 0.2 GO:1901567 icosanoid binding(GO:0050542) arachidonic acid binding(GO:0050544) fatty acid derivative binding(GO:1901567)
0.0 0.2 GO:0070728 leucine binding(GO:0070728)
0.0 0.3 GO:0005168 neurotrophin TRKA receptor binding(GO:0005168)
0.0 2.0 GO:0004004 RNA helicase activity(GO:0003724) ATP-dependent RNA helicase activity(GO:0004004)
0.0 0.6 GO:0008009 chemokine activity(GO:0008009)
0.0 0.6 GO:0003746 translation elongation factor activity(GO:0003746)
0.0 1.5 GO:0005518 collagen binding(GO:0005518)
0.0 0.3 GO:0019855 calcium channel inhibitor activity(GO:0019855)
0.0 0.8 GO:0005246 calcium channel regulator activity(GO:0005246)
0.0 0.4 GO:0005540 hyaluronic acid binding(GO:0005540)
0.0 0.5 GO:0005184 neuropeptide hormone activity(GO:0005184)
0.0 0.4 GO:0005078 MAP-kinase scaffold activity(GO:0005078)
0.0 0.8 GO:0043548 phosphatidylinositol 3-kinase binding(GO:0043548)
0.0 0.1 GO:0000298 endopolyphosphatase activity(GO:0000298) diphosphoinositol-polyphosphate diphosphatase activity(GO:0008486) bis(5'-adenosyl)-hexaphosphatase activity(GO:0034431) bis(5'-adenosyl)-pentaphosphatase activity(GO:0034432)
0.0 0.5 GO:0080025 phosphatidylinositol-3,5-bisphosphate binding(GO:0080025)
0.0 0.6 GO:0035255 ionotropic glutamate receptor binding(GO:0035255)
0.0 0.2 GO:0000340 RNA 7-methylguanosine cap binding(GO:0000340)
0.0 0.3 GO:0001968 fibronectin binding(GO:0001968)
0.0 0.1 GO:0019784 NEDD8-specific protease activity(GO:0019784)
0.0 0.2 GO:0004576 oligosaccharyl transferase activity(GO:0004576) dolichyl-diphosphooligosaccharide-protein glycotransferase activity(GO:0004579)
0.0 2.0 GO:0030165 PDZ domain binding(GO:0030165)
0.0 0.1 GO:0004416 hydroxyacylglutathione hydrolase activity(GO:0004416)
0.0 0.2 GO:0050431 transforming growth factor beta binding(GO:0050431)
0.0 0.2 GO:0005545 1-phosphatidylinositol binding(GO:0005545)
0.0 0.5 GO:0046875 ephrin receptor binding(GO:0046875)
0.0 0.7 GO:0004722 protein serine/threonine phosphatase activity(GO:0004722)
0.0 2.8 GO:0005543 phospholipid binding(GO:0005543)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 8.7 PID_ARF6_PATHWAY Arf6 signaling events
0.1 4.1 PID_ARF_3PATHWAY Arf1 pathway
0.1 2.7 PID_IL12_STAT4_PATHWAY IL12 signaling mediated by STAT4
0.1 3.3 PID_RXR_VDR_PATHWAY RXR and RAR heterodimerization with other nuclear receptor
0.1 2.5 PID_FRA_PATHWAY Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.1 3.6 PID_PI3K_PLC_TRK_PATHWAY Trk receptor signaling mediated by PI3K and PLC-gamma
0.1 0.5 PID_INTEGRIN4_PATHWAY Alpha6 beta4 integrin-ligand interactions
0.1 1.9 PID_NETRIN_PATHWAY Netrin-mediated signaling events
0.1 4.5 PID_MYC_REPRESS_PATHWAY Validated targets of C-MYC transcriptional repression
0.1 1.4 PID_PRL_SIGNALING_EVENTS_PATHWAY Signaling events mediated by PRL
0.1 1.5 PID_GLYPICAN_1PATHWAY Glypican 1 network
0.0 0.8 PID_IGF1_PATHWAY IGF1 pathway
0.0 1.8 PID_ATM_PATHWAY ATM pathway
0.0 1.2 NABA_BASEMENT_MEMBRANES Genes encoding structural components of basement membranes
0.0 2.4 PID_TRKR_PATHWAY Neurotrophic factor-mediated Trk receptor signaling
0.0 1.6 PID_CERAMIDE_PATHWAY Ceramide signaling pathway
0.0 1.8 PID_LYSOPHOSPHOLIPID_PATHWAY LPA receptor mediated events
0.0 0.8 PID_PI3KCI_PATHWAY Class I PI3K signaling events
0.0 0.5 PID_CXCR3_PATHWAY CXCR3-mediated signaling events
0.0 0.7 PID_IL2_PI3K_PATHWAY IL2 signaling events mediated by PI3K
0.0 0.4 PID_FAK_PATHWAY Signaling events mediated by focal adhesion kinase
0.0 1.1 PID_HNF3A_PATHWAY FOXA1 transcription factor network
0.0 1.2 PID_ERBB1_INTERNALIZATION_PATHWAY Internalization of ErbB1
0.0 3.0 NABA_ECM_AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.0 0.4 PID_EPHRINB_REV_PATHWAY Ephrin B reverse signaling
0.0 1.0 PID_P38_ALPHA_BETA_DOWNSTREAM_PATHWAY Signaling mediated by p38-alpha and p38-beta
0.0 0.3 PID_ERBB2_ERBB3_PATHWAY ErbB2/ErbB3 signaling events
0.0 0.3 PID_ARF6_TRAFFICKING_PATHWAY Arf6 trafficking events
0.0 0.1 PID_TRAIL_PATHWAY TRAIL signaling pathway
0.0 0.2 PID_ARF6_DOWNSTREAM_PATHWAY Arf6 downstream pathway
0.0 0.5 PID_TAP63_PATHWAY Validated transcriptional targets of TAp63 isoforms
0.0 0.3 PID_P38_MKK3_6PATHWAY p38 MAPK signaling pathway
0.0 0.5 PID_MTOR_4PATHWAY mTOR signaling pathway
0.0 0.1 PID_LYMPH_ANGIOGENESIS_PATHWAY VEGFR3 signaling in lymphatic endothelium

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 8.0 REACTOME_SEMA4D_IN_SEMAPHORIN_SIGNALING Genes involved in Sema4D in semaphorin signaling
0.2 3.7 REACTOME_GAP_JUNCTION_DEGRADATION Genes involved in Gap junction degradation
0.1 1.8 REACTOME_NUCLEOTIDE_LIKE_PURINERGIC_RECEPTORS Genes involved in Nucleotide-like (purinergic) receptors
0.1 1.7 REACTOME_ROLE_OF_DCC_IN_REGULATING_APOPTOSIS Genes involved in Role of DCC in regulating apoptosis
0.1 2.1 REACTOME_HOMOLOGOUS_RECOMBINATION_REPAIR_OF_REPLICATION_INDEPENDENT_DOUBLE_STRAND_BREAKS Genes involved in Homologous recombination repair of replication-independent double-strand breaks
0.1 2.8 REACTOME_GLUCONEOGENESIS Genes involved in Gluconeogenesis
0.1 1.2 REACTOME_CS_DS_DEGRADATION Genes involved in CS/DS degradation
0.1 3.4 REACTOME_CA_DEPENDENT_EVENTS Genes involved in Ca-dependent events
0.1 0.4 REACTOME_SIGNALLING_TO_P38_VIA_RIT_AND_RIN Genes involved in Signalling to p38 via RIT and RIN
0.1 0.7 REACTOME_ACETYLCHOLINE_NEUROTRANSMITTER_RELEASE_CYCLE Genes involved in Acetylcholine Neurotransmitter Release Cycle
0.1 1.2 REACTOME_PURINE_SALVAGE Genes involved in Purine salvage
0.1 1.2 REACTOME_SOS_MEDIATED_SIGNALLING Genes involved in SOS-mediated signalling
0.1 0.5 REACTOME_GAMMA_CARBOXYLATION_TRANSPORT_AND_AMINO_TERMINAL_CLEAVAGE_OF_PROTEINS Genes involved in Gamma-carboxylation, transport, and amino-terminal cleavage of proteins
0.1 1.7 REACTOME_EGFR_DOWNREGULATION Genes involved in EGFR downregulation
0.1 0.8 REACTOME_POST_CHAPERONIN_TUBULIN_FOLDING_PATHWAY Genes involved in Post-chaperonin tubulin folding pathway
0.1 0.5 REACTOME_PYRIMIDINE_CATABOLISM Genes involved in Pyrimidine catabolism
0.0 3.3 REACTOME_NUCLEAR_RECEPTOR_TRANSCRIPTION_PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.0 2.0 REACTOME_TRANSPORT_OF_VITAMINS_NUCLEOSIDES_AND_RELATED_MOLECULES Genes involved in Transport of vitamins, nucleosides, and related molecules
0.0 1.3 REACTOME_SYNTHESIS_AND_INTERCONVERSION_OF_NUCLEOTIDE_DI_AND_TRIPHOSPHATES Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.0 3.3 REACTOME_MEIOTIC_SYNAPSIS Genes involved in Meiotic Synapsis
0.0 0.9 REACTOME_ABCA_TRANSPORTERS_IN_LIPID_HOMEOSTASIS Genes involved in ABCA transporters in lipid homeostasis
0.0 1.4 REACTOME_DOWNREGULATION_OF_TGF_BETA_RECEPTOR_SIGNALING Genes involved in Downregulation of TGF-beta receptor signaling
0.0 1.0 REACTOME_RECYCLING_PATHWAY_OF_L1 Genes involved in Recycling pathway of L1
0.0 0.7 REACTOME_RNA_POL_III_CHAIN_ELONGATION Genes involved in RNA Polymerase III Chain Elongation
0.0 1.0 REACTOME_SMOOTH_MUSCLE_CONTRACTION Genes involved in Smooth Muscle Contraction
0.0 1.6 REACTOME_NCAM1_INTERACTIONS Genes involved in NCAM1 interactions
0.0 0.6 REACTOME_N_GLYCAN_ANTENNAE_ELONGATION Genes involved in N-Glycan antennae elongation
0.0 0.3 REACTOME_DEGRADATION_OF_THE_EXTRACELLULAR_MATRIX Genes involved in Degradation of the extracellular matrix
0.0 0.8 REACTOME_INTERACTION_BETWEEN_L1_AND_ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.0 1.7 REACTOME_RESPONSE_TO_ELEVATED_PLATELET_CYTOSOLIC_CA2_ Genes involved in Response to elevated platelet cytosolic Ca2+
0.0 0.5 REACTOME_CHEMOKINE_RECEPTORS_BIND_CHEMOKINES Genes involved in Chemokine receptors bind chemokines
0.0 0.4 REACTOME_CGMP_EFFECTS Genes involved in cGMP effects
0.0 0.3 REACTOME_DOWNREGULATION_OF_ERBB2_ERBB3_SIGNALING Genes involved in Downregulation of ERBB2:ERBB3 signaling
0.0 0.2 REACTOME_PROTEOLYTIC_CLEAVAGE_OF_SNARE_COMPLEX_PROTEINS Genes involved in Proteolytic cleavage of SNARE complex proteins
0.0 0.2 REACTOME_SYNTHESIS_OF_PE Genes involved in Synthesis of PE
0.0 1.9 REACTOME_PPARA_ACTIVATES_GENE_EXPRESSION Genes involved in PPARA Activates Gene Expression
0.0 0.3 REACTOME_BRANCHED_CHAIN_AMINO_ACID_CATABOLISM Genes involved in Branched-chain amino acid catabolism
0.0 0.6 REACTOME_SPHINGOLIPID_DE_NOVO_BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis
0.0 0.6 REACTOME_L1CAM_INTERACTIONS Genes involved in L1CAM interactions
0.0 0.5 REACTOME_O_LINKED_GLYCOSYLATION_OF_MUCINS Genes involved in O-linked glycosylation of mucins
0.0 0.8 REACTOME_DOWNSTREAM_SIGNAL_TRANSDUCTION Genes involved in Downstream signal transduction
0.0 0.2 REACTOME_RNA_POL_I_PROMOTER_OPENING Genes involved in RNA Polymerase I Promoter Opening
0.0 0.3 REACTOME_KINESINS Genes involved in Kinesins
0.0 0.2 REACTOME_HORMONE_SENSITIVE_LIPASE_HSL_MEDIATED_TRIACYLGLYCEROL_HYDROLYSIS Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.0 1.1 REACTOME_TRANSPORT_OF_INORGANIC_CATIONS_ANIONS_AND_AMINO_ACIDS_OLIGOPEPTIDES Genes involved in Transport of inorganic cations/anions and amino acids/oligopeptides