Motif ID: Foxd2

Z-value: 0.680


Transcription factors associated with Foxd2:

Gene SymbolEntrez IDGene Name
Foxd2 ENSMUSG00000055210.3 Foxd2



Activity profile for motif Foxd2.

activity profile for motif Foxd2


Sorted Z-values histogram for motif Foxd2

Sorted Z-values for motif Foxd2



Network of associatons between targets according to the STRING database.



First level regulatory network of Foxd2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr14_+_101840602 6.538 ENSMUST00000159314.1
Lmo7
LIM domain only 7
chr14_+_101840501 5.931 ENSMUST00000159026.1
Lmo7
LIM domain only 7
chr5_-_104114088 4.595 ENSMUST00000031249.3
Sparcl1
SPARC-like 1
chr18_+_37504264 4.377 ENSMUST00000052179.6
Pcdhb20
protocadherin beta 20
chr4_-_136898803 4.348 ENSMUST00000046285.5
C1qa
complement component 1, q subcomponent, alpha polypeptide
chr4_-_14621805 3.937 ENSMUST00000042221.7
Slc26a7
solute carrier family 26, member 7
chr15_+_3270767 3.668 ENSMUST00000082424.4
ENSMUST00000159158.1
ENSMUST00000159216.1
ENSMUST00000160311.1
Sepp1



selenoprotein P, plasma, 1



chr18_+_51117754 3.663 ENSMUST00000116639.2
Prr16
proline rich 16
chr13_+_16014457 3.335 ENSMUST00000164993.1
Inhba
inhibin beta-A
chr14_+_80000292 2.807 ENSMUST00000088735.3
Olfm4
olfactomedin 4
chr15_+_92597104 2.799 ENSMUST00000035399.8
Pdzrn4
PDZ domain containing RING finger 4
chr14_-_30353468 2.755 ENSMUST00000112249.1
Cacna1d
calcium channel, voltage-dependent, L type, alpha 1D subunit
chr9_-_20879718 2.040 ENSMUST00000043726.6
Angptl6
angiopoietin-like 6
chr18_+_37513652 2.037 ENSMUST00000061405.4
Pcdhb21
protocadherin beta 21
chr4_-_14621669 1.969 ENSMUST00000143105.1
Slc26a7
solute carrier family 26, member 7
chr16_+_43508118 1.958 ENSMUST00000114690.1
Zbtb20
zinc finger and BTB domain containing 20
chr2_-_45110336 1.950 ENSMUST00000028229.6
ENSMUST00000152232.1
Zeb2

zinc finger E-box binding homeobox 2

chr3_+_89520152 1.934 ENSMUST00000000811.7
Kcnn3
potassium intermediate/small conductance calcium-activated channel, subfamily N, member 3
chr19_+_26748268 1.933 ENSMUST00000175791.1
ENSMUST00000176698.1
ENSMUST00000177252.1
ENSMUST00000176475.1
ENSMUST00000112637.2
Smarca2




SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2




chr6_+_77242644 1.797 ENSMUST00000159616.1
Lrrtm1
leucine rich repeat transmembrane neuronal 1
chr9_-_95750335 1.751 ENSMUST00000053785.3
Trpc1
transient receptor potential cation channel, subfamily C, member 1
chr6_+_77242715 1.740 ENSMUST00000161677.1
Lrrtm1
leucine rich repeat transmembrane neuronal 1
chr1_-_157256682 1.722 ENSMUST00000134543.1
Rasal2
RAS protein activator like 2
chr11_+_75650501 1.638 ENSMUST00000102505.3
Myo1c
myosin IC
chr10_+_67096456 1.621 ENSMUST00000174317.1
Jmjd1c
jumonji domain containing 1C
chrX_+_159697308 1.581 ENSMUST00000123433.1
Sh3kbp1
SH3-domain kinase binding protein 1
chr1_-_126830786 1.573 ENSMUST00000162646.1
Nckap5
NCK-associated protein 5
chr1_-_126830632 1.504 ENSMUST00000112583.1
ENSMUST00000094609.3
Nckap5

NCK-associated protein 5

chr16_+_43235856 1.348 ENSMUST00000146708.1
Zbtb20
zinc finger and BTB domain containing 20
chrX_-_105929333 1.319 ENSMUST00000134507.1
ENSMUST00000137453.1
ENSMUST00000150914.1
Atrx


alpha thalassemia/mental retardation syndrome X-linked homolog (human)


chr5_-_31295862 1.304 ENSMUST00000041266.7
ENSMUST00000172435.1
Fndc4

fibronectin type III domain containing 4

chrX_-_105929206 1.285 ENSMUST00000134381.1
ENSMUST00000154866.1
Atrx

alpha thalassemia/mental retardation syndrome X-linked homolog (human)

chr16_-_4880284 1.161 ENSMUST00000037843.6
Ubald1
UBA-like domain containing 1
chr19_+_57452900 1.150 ENSMUST00000026073.6
ENSMUST00000026072.3
Trub1

TruB pseudouridine (psi) synthase homolog 1 (E. coli)

chr11_-_69369377 1.104 ENSMUST00000092971.6
ENSMUST00000108661.1
Chd3

chromodomain helicase DNA binding protein 3

chr12_+_103434211 1.074 ENSMUST00000079294.5
ENSMUST00000076788.5
ENSMUST00000076702.5
ENSMUST00000066701.6
ENSMUST00000085065.5
ENSMUST00000140838.1
Ifi27





interferon, alpha-inducible protein 27





chr13_+_83732438 0.970 ENSMUST00000182701.1
C130071C03Rik
RIKEN cDNA C130071C03 gene
chr2_+_125136692 0.957 ENSMUST00000099452.2
Ctxn2
cortexin 2
chr6_+_136518820 0.956 ENSMUST00000032335.6
Atf7ip
activating transcription factor 7 interacting protein
chr17_-_78418083 0.944 ENSMUST00000070039.7
ENSMUST00000112487.1
Fez2

fasciculation and elongation protein zeta 2 (zygin II)

chr6_+_13069758 0.923 ENSMUST00000124234.1
ENSMUST00000142211.1
ENSMUST00000031556.7
Tmem106b


transmembrane protein 106B


chr16_+_13986596 0.851 ENSMUST00000056521.5
ENSMUST00000118412.1
ENSMUST00000131608.1
2900011O08Rik


RIKEN cDNA 2900011O08 gene


chr18_+_37725706 0.842 ENSMUST00000066149.6
Pcdhga9
protocadherin gamma subfamily A, 9
chr4_-_82850721 0.838 ENSMUST00000139401.1
Zdhhc21
zinc finger, DHHC domain containing 21
chr9_+_54980880 0.826 ENSMUST00000093844.3
Chrna5
cholinergic receptor, nicotinic, alpha polypeptide 5
chr2_-_122702615 0.818 ENSMUST00000005952.4
ENSMUST00000099457.3
Slc30a4

solute carrier family 30 (zinc transporter), member 4

chr13_-_18031616 0.816 ENSMUST00000099736.2
Vdac3-ps1
voltage-dependent anion channel 3, pseudogene 1
chr15_+_78935177 0.738 ENSMUST00000145157.1
ENSMUST00000123013.1
Nol12

nucleolar protein 12

chr5_+_107497762 0.738 ENSMUST00000152474.1
ENSMUST00000060553.7
A830010M20Rik

RIKEN cDNA A830010M20 gene

chr5_-_103100054 0.701 ENSMUST00000112848.1
Mapk10
mitogen-activated protein kinase 10
chr1_+_171840607 0.687 ENSMUST00000136479.1
ENSMUST00000042302.6
Cd84

CD84 antigen

chr18_+_37674303 0.686 ENSMUST00000073447.5
Pcdhga9
protocadherin gamma subfamily A, 9
chr2_+_120977017 0.669 ENSMUST00000067582.7
Tmem62
transmembrane protein 62
chr5_+_107497718 0.662 ENSMUST00000112671.2
A830010M20Rik
RIKEN cDNA A830010M20 gene
chr9_-_78109020 0.643 ENSMUST00000001402.7
Fbxo9
f-box protein 9
chr15_-_98607611 0.642 ENSMUST00000096224.4
Adcy6
adenylate cyclase 6
chr6_-_54972603 0.627 ENSMUST00000060655.8
Nod1
nucleotide-binding oligomerization domain containing 1
chr9_-_90270712 0.604 ENSMUST00000041767.7
ENSMUST00000144348.1
Tbc1d2b

TBC1 domain family, member 2B

chr7_-_61982348 0.560 ENSMUST00000181804.1
ENSMUST00000181187.1
A330076H08Rik

RIKEN cDNA A330076H08 gene

chrX_-_105929397 0.542 ENSMUST00000113573.1
ENSMUST00000130980.1
Atrx

alpha thalassemia/mental retardation syndrome X-linked homolog (human)

chr1_-_170867761 0.527 ENSMUST00000027974.6
Atf6
activating transcription factor 6
chr1_-_37496095 0.496 ENSMUST00000148047.1
ENSMUST00000143636.1
Mgat4a

mannoside acetylglucosaminyltransferase 4, isoenzyme A

chr2_-_73312701 0.465 ENSMUST00000058615.9
Cir1
corepressor interacting with RBPJ, 1
chr17_-_56276750 0.412 ENSMUST00000058136.8
Ticam1
toll-like receptor adaptor molecule 1
chr4_+_108847827 0.411 ENSMUST00000102738.2
Kti12
KTI12 homolog, chromatin associated (S. cerevisiae)
chr13_+_5861489 0.404 ENSMUST00000000080.6
Klf6
Kruppel-like factor 6
chr12_-_110840905 0.378 ENSMUST00000177224.1
ENSMUST00000084974.4
ENSMUST00000070565.8
Stk30


serine/threonine kinase 30


chr7_-_14562171 0.365 ENSMUST00000181796.1
Vmn1r90
vomeronasal 1 receptor 90
chr6_+_38918969 0.350 ENSMUST00000003017.6
Tbxas1
thromboxane A synthase 1, platelet
chr19_-_31765027 0.344 ENSMUST00000065067.6
Prkg1
protein kinase, cGMP-dependent, type I
chr9_-_89092835 0.291 ENSMUST00000167113.1
Trim43b
tripartite motif-containing 43B
chr5_+_24393640 0.291 ENSMUST00000138168.1
ENSMUST00000115077.1
Abcb8

ATP-binding cassette, sub-family B (MDR/TAP), member 8

chr12_-_101958148 0.286 ENSMUST00000159883.1
ENSMUST00000160251.1
ENSMUST00000161011.1
ENSMUST00000021606.5
Atxn3



ataxin 3



chr10_-_128744014 0.283 ENSMUST00000026414.7
Dgka
diacylglycerol kinase, alpha
chr11_+_97801917 0.281 ENSMUST00000127033.2
Lasp1
LIM and SH3 protein 1
chr9_+_36832684 0.277 ENSMUST00000034630.8
Fez1
fasciculation and elongation protein zeta 1 (zygin I)
chr1_-_132367879 0.250 ENSMUST00000142609.1
Tmcc2
transmembrane and coiled-coil domains 2
chr2_+_14388316 0.232 ENSMUST00000114731.1
ENSMUST00000082290.7
Slc39a12

solute carrier family 39 (zinc transporter), member 12

chr1_-_118311132 0.220 ENSMUST00000027623.7
Tsn
translin
chr9_+_78109188 0.219 ENSMUST00000118869.1
ENSMUST00000125615.1
Ick

intestinal cell kinase

chr14_-_70630149 0.196 ENSMUST00000022694.9
Dmtn
dematin actin binding protein
chr10_-_39122277 0.179 ENSMUST00000136546.1
Fam229b
family with sequence similarity 229, member B
chr7_-_127195875 0.177 ENSMUST00000035771.3
ENSMUST00000166791.1
Cd2bp2

CD2 antigen (cytoplasmic tail) binding protein 2

chr19_-_8713862 0.164 ENSMUST00000010239.4
Slc3a2
solute carrier family 3 (activators of dibasic and neutral amino acid transport), member 2
chr5_+_104046980 0.164 ENSMUST00000134313.1
Nudt9
nudix (nucleoside diphosphate linked moiety X)-type motif 9
chr4_+_150087365 0.147 ENSMUST00000094451.3
Gpr157
G protein-coupled receptor 157
chr15_+_99393574 0.117 ENSMUST00000162624.1
Tmbim6
transmembrane BAX inhibitor motif containing 6
chr14_-_45388772 0.114 ENSMUST00000046191.7
Gnpnat1
glucosamine-phosphate N-acetyltransferase 1
chr13_+_119606650 0.111 ENSMUST00000178948.1
Gm21967
predicted gene, 21967
chr19_-_29753600 0.109 ENSMUST00000175764.1
9930021J03Rik
RIKEN cDNA 9930021J03 gene
chr7_+_43634718 0.104 ENSMUST00000032663.8
Ceacam18
carcinoembryonic antigen-related cell adhesion molecule 18
chr15_-_44428303 0.102 ENSMUST00000038719.6
Nudcd1
NudC domain containing 1
chr10_+_11609256 0.093 ENSMUST00000052902.7
Gm9797
predicted pseudogene 9797
chr10_-_89621253 0.071 ENSMUST00000020102.7
Slc17a8
solute carrier family 17 (sodium-dependent inorganic phosphate cotransporter), member 8
chr4_+_32243733 0.069 ENSMUST00000165661.1
D130062J21Rik
RIKEN cDNA D130062J21 gene
chr1_-_165934900 0.034 ENSMUST00000069609.5
ENSMUST00000111427.2
ENSMUST00000111426.4
Pou2f1


POU domain, class 2, transcription factor 1


chr7_-_87493371 0.025 ENSMUST00000004770.5
Tyr
tyrosinase
chr14_-_52213379 0.018 ENSMUST00000140603.1
Chd8
chromodomain helicase DNA binding protein 8
chr5_-_120612558 0.011 ENSMUST00000140554.1
ENSMUST00000031599.2
ENSMUST00000177800.1
1110008J03Rik


RIKEN cDNA 1110008J03 gene



Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 5.9 GO:0019532 oxalate transport(GO:0019532)
0.8 3.1 GO:0097393 post-embryonic appendage morphogenesis(GO:0035120) post-embryonic limb morphogenesis(GO:0035127) post-embryonic forelimb morphogenesis(GO:0035128) telomeric repeat-containing RNA transcription(GO:0097393) telomeric repeat-containing RNA transcription from RNA pol II promoter(GO:0097394) regulation of telomeric RNA transcription from RNA pol II promoter(GO:1901580) negative regulation of telomeric RNA transcription from RNA pol II promoter(GO:1901581) positive regulation of telomeric RNA transcription from RNA pol II promoter(GO:1901582)
0.7 2.8 GO:0086046 membrane depolarization during SA node cell action potential(GO:0086046)
0.7 3.3 GO:0042636 negative regulation of hair cycle(GO:0042636) progesterone secretion(GO:0042701) negative regulation of hair follicle development(GO:0051799) positive regulation of ovulation(GO:0060279)
0.3 1.6 GO:1900748 positive regulation of vascular endothelial growth factor signaling pathway(GO:1900748)
0.3 1.9 GO:1903056 positive regulation of lens fiber cell differentiation(GO:1902748) regulation of melanosome organization(GO:1903056)
0.3 0.9 GO:1903976 negative regulation of glial cell migration(GO:1903976)
0.2 1.6 GO:0030718 germ-line stem cell population maintenance(GO:0030718)
0.2 0.7 GO:2001180 negative regulation of interleukin-18 production(GO:0032701) negative regulation of interleukin-10 secretion(GO:2001180)
0.2 1.9 GO:0035887 aortic smooth muscle cell differentiation(GO:0035887)
0.2 0.6 GO:0035811 negative regulation of urine volume(GO:0035811)
0.2 1.2 GO:1990481 mRNA pseudouridine synthesis(GO:1990481)
0.2 1.8 GO:0046541 saliva secretion(GO:0046541)
0.2 3.8 GO:0006958 complement activation, classical pathway(GO:0006958)
0.2 3.7 GO:0045793 positive regulation of cell size(GO:0045793)
0.1 0.4 GO:0045359 positive regulation of interferon-beta biosynthetic process(GO:0045359)
0.1 0.6 GO:0042228 positive regulation of dendritic cell antigen processing and presentation(GO:0002606) detection of bacterium(GO:0016045) interleukin-8 biosynthetic process(GO:0042228) detection of other organism(GO:0098543)
0.1 0.7 GO:0007258 JUN phosphorylation(GO:0007258)
0.1 3.1 GO:0002091 negative regulation of receptor internalization(GO:0002091)
0.1 0.3 GO:2000224 regulation of testosterone biosynthetic process(GO:2000224)
0.1 1.2 GO:1902902 negative regulation of autophagosome assembly(GO:1902902)
0.1 0.8 GO:0035095 behavioral response to nicotine(GO:0035095)
0.1 0.8 GO:0061088 sequestering of zinc ion(GO:0032119) regulation of sequestering of zinc ion(GO:0061088)
0.1 3.3 GO:0032728 positive regulation of interferon-beta production(GO:0032728)
0.1 0.8 GO:0048733 peptidyl-L-cysteine S-palmitoylation(GO:0018230) peptidyl-S-diacylglycerol-L-cysteine biosynthetic process from peptidyl-cysteine(GO:0018231) sebaceous gland development(GO:0048733)
0.1 0.2 GO:0035585 calcium-mediated signaling using extracellular calcium source(GO:0035585)
0.1 2.8 GO:1900026 positive regulation of substrate adhesion-dependent cell spreading(GO:1900026)
0.1 1.0 GO:0045898 regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0045898)
0.1 0.3 GO:0030644 cellular chloride ion homeostasis(GO:0030644)
0.1 0.2 GO:0046032 ADP catabolic process(GO:0046032)
0.0 0.2 GO:0035720 intraciliary anterograde transport(GO:0035720)
0.0 0.5 GO:1990440 positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress(GO:1990440)
0.0 6.4 GO:0007416 synapse assembly(GO:0007416)
0.0 0.2 GO:0015803 branched-chain amino acid transport(GO:0015803) leucine transport(GO:0015820)
0.0 0.1 GO:0006041 glucosamine metabolic process(GO:0006041)
0.0 1.7 GO:0046580 negative regulation of Ras protein signal transduction(GO:0046580)
0.0 0.3 GO:0035520 monoubiquitinated protein deubiquitination(GO:0035520)
0.0 0.3 GO:0046339 diacylglycerol metabolic process(GO:0046339)
0.0 1.1 GO:0046825 regulation of protein export from nucleus(GO:0046825)
0.0 1.9 GO:1903955 positive regulation of protein targeting to mitochondrion(GO:1903955)
0.0 0.1 GO:1904721 regulation of mRNA cleavage(GO:0031437) negative regulation of mRNA cleavage(GO:0031438) negative regulation of immunoglobulin secretion(GO:0051025) regulation of mRNA endonucleolytic cleavage involved in unfolded protein response(GO:1904720) negative regulation of mRNA endonucleolytic cleavage involved in unfolded protein response(GO:1904721)
0.0 0.6 GO:0031146 SCF-dependent proteasomal ubiquitin-dependent protein catabolic process(GO:0031146)
0.0 0.9 GO:0032418 lysosome localization(GO:0032418)
0.0 0.1 GO:0060019 radial glial cell differentiation(GO:0060019)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
1.1 3.3 GO:0043512 inhibin A complex(GO:0043512)
0.8 3.1 GO:1990421 subtelomeric heterochromatin(GO:1990421) nuclear subtelomeric heterochromatin(GO:1990707)
0.5 1.6 GO:0045160 myosin I complex(GO:0045160)
0.3 2.8 GO:1990454 L-type voltage-gated calcium channel complex(GO:1990454)
0.2 2.8 GO:0042581 specific granule(GO:0042581)
0.1 1.7 GO:0031235 intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235)
0.1 1.9 GO:0071564 npBAF complex(GO:0071564)
0.1 11.6 GO:0005913 cell-cell adherens junction(GO:0005913)
0.1 0.8 GO:0005892 acetylcholine-gated channel complex(GO:0005892)
0.1 4.3 GO:0005581 collagen trimer(GO:0005581)
0.1 0.4 GO:0097342 ripoptosome(GO:0097342)
0.0 0.2 GO:0031095 platelet dense tubular network membrane(GO:0031095)
0.0 1.1 GO:0016581 NuRD complex(GO:0016581) CHD-type complex(GO:0090545)
0.0 1.8 GO:0043034 costamere(GO:0043034)
0.0 0.6 GO:0031528 microvillus membrane(GO:0031528)
0.0 0.1 GO:0097441 basilar dendrite(GO:0097441)
0.0 1.1 GO:0005637 nuclear inner membrane(GO:0005637)
0.0 6.5 GO:0016323 basolateral plasma membrane(GO:0016323)
0.0 1.9 GO:0031594 neuromuscular junction(GO:0031594)
0.0 4.6 GO:0005578 proteinaceous extracellular matrix(GO:0005578)
0.0 0.3 GO:0042405 nuclear inclusion body(GO:0042405)
0.0 0.2 GO:0097542 ciliary tip(GO:0097542)
0.0 3.0 GO:0030426 growth cone(GO:0030426)
0.0 1.6 GO:0030139 endocytic vesicle(GO:0030139)
0.0 2.4 GO:0030141 secretory granule(GO:0030141)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 3.3 GO:0070699 type II activin receptor binding(GO:0070699)
0.5 5.9 GO:0019531 secondary active sulfate transmembrane transporter activity(GO:0008271) oxalate transmembrane transporter activity(GO:0019531)
0.5 1.9 GO:0016286 small conductance calcium-activated potassium channel activity(GO:0016286)
0.4 3.1 GO:0015616 DNA translocase activity(GO:0015616)
0.4 15.2 GO:0042805 actinin binding(GO:0042805)
0.2 0.7 GO:0016909 JUN kinase activity(GO:0004705) SAP kinase activity(GO:0016909)
0.2 1.8 GO:0015279 store-operated calcium channel activity(GO:0015279)
0.1 0.6 GO:0050700 CARD domain binding(GO:0050700)
0.1 1.6 GO:0030898 actin-dependent ATPase activity(GO:0030898)
0.1 0.6 GO:0008294 calcium- and calmodulin-responsive adenylate cyclase activity(GO:0008294)
0.1 0.5 GO:0008454 alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity(GO:0008454)
0.1 0.3 GO:0004692 cGMP-dependent protein kinase activity(GO:0004692)
0.1 1.6 GO:0032454 histone demethylase activity (H3-K9 specific)(GO:0032454)
0.1 4.6 GO:0050840 extracellular matrix binding(GO:0050840)
0.1 0.8 GO:0022848 acetylcholine-gated cation channel activity(GO:0022848)
0.1 1.2 GO:0009982 pseudouridine synthase activity(GO:0009982)
0.1 1.1 GO:0005521 lamin binding(GO:0005521)
0.0 1.9 GO:0070412 R-SMAD binding(GO:0070412)
0.0 0.3 GO:1990380 Lys48-specific deubiquitinase activity(GO:1990380)
0.0 1.9 GO:0001105 RNA polymerase II transcription coactivator activity(GO:0001105)
0.0 0.5 GO:0035497 cAMP response element binding(GO:0035497)
0.0 0.8 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.0 0.8 GO:0019707 protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)
0.0 0.3 GO:0004143 diacylglycerol kinase activity(GO:0004143)
0.0 0.2 GO:0047631 ADP-ribose diphosphatase activity(GO:0047631)
0.0 3.3 GO:0001078 transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078)
0.0 0.1 GO:0060698 endoribonuclease inhibitor activity(GO:0060698)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 3.3 PID_ALK1_PATHWAY ALK1 signaling events
0.0 0.6 PID_LPA4_PATHWAY LPA4-mediated signaling events
0.0 4.3 NABA_ECM_AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.0 0.7 PID_NEPHRIN_NEPH1_PATHWAY Nephrin/Neph1 signaling in the kidney podocyte
0.0 1.6 PID_ERBB1_INTERNALIZATION_PATHWAY Internalization of ErbB1
0.0 2.0 PID_AR_TF_PATHWAY Regulation of Androgen receptor activity
0.0 3.3 NABA_ECM_GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.0 0.4 ST_ERK1_ERK2_MAPK_PATHWAY ERK1/ERK2 MAPK Pathway
0.0 0.4 PID_TOLL_ENDOGENOUS_PATHWAY Endogenous TLR signaling
0.0 0.3 PID_P38_ALPHA_BETA_PATHWAY Regulation of p38-alpha and p38-beta
0.0 1.1 PID_HDAC_CLASSI_PATHWAY Signaling events mediated by HDAC Class I
0.0 1.1 SIG_PIP3_SIGNALING_IN_CARDIAC_MYOCTES Genes related to PIP3 signaling in cardiac myocytes
0.0 0.4 PID_P38_ALPHA_BETA_DOWNSTREAM_PATHWAY Signaling mediated by p38-alpha and p38-beta
0.0 0.4 PID_NFAT_TFPATHWAY Calcineurin-regulated NFAT-dependent transcription in lymphocytes

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 3.3 REACTOME_GLYCOPROTEIN_HORMONES Genes involved in Glycoprotein hormones
0.6 3.8 REACTOME_CREATION_OF_C4_AND_C2_ACTIVATORS Genes involved in Creation of C4 and C2 activators
0.1 0.8 REACTOME_PRESYNAPTIC_NICOTINIC_ACETYLCHOLINE_RECEPTORS Genes involved in Presynaptic nicotinic acetylcholine receptors
0.1 6.1 REACTOME_TRANSPORT_OF_INORGANIC_CATIONS_ANIONS_AND_AMINO_ACIDS_OLIGOPEPTIDES Genes involved in Transport of inorganic cations/anions and amino acids/oligopeptides
0.1 0.4 REACTOME_TRAF6_MEDIATED_INDUCTION_OF_TAK1_COMPLEX Genes involved in TRAF6 mediated induction of TAK1 complex
0.1 0.5 REACTOME_ACTIVATION_OF_CHAPERONE_GENES_BY_ATF6_ALPHA Genes involved in Activation of Chaperone Genes by ATF6-alpha
0.1 1.3 REACTOME_JNK_C_JUN_KINASES_PHOSPHORYLATION_AND_ACTIVATION_MEDIATED_BY_ACTIVATED_HUMAN_TAK1 Genes involved in JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1
0.1 0.6 REACTOME_ADENYLATE_CYCLASE_ACTIVATING_PATHWAY Genes involved in Adenylate cyclase activating pathway
0.0 1.6 REACTOME_ANTIGEN_ACTIVATES_B_CELL_RECEPTOR_LEADING_TO_GENERATION_OF_SECOND_MESSENGERS Genes involved in Antigen Activates B Cell Receptor Leading to Generation of Second Messengers
0.0 0.8 REACTOME_ENOS_ACTIVATION_AND_REGULATION Genes involved in eNOS activation and regulation
0.0 0.3 REACTOME_CYTOCHROME_P450_ARRANGED_BY_SUBSTRATE_TYPE Genes involved in Cytochrome P450 - arranged by substrate type
0.0 0.5 REACTOME_N_GLYCAN_ANTENNAE_ELONGATION Genes involved in N-Glycan antennae elongation
0.0 1.9 REACTOME_POTASSIUM_CHANNELS Genes involved in Potassium Channels
0.0 0.7 REACTOME_INTERFERON_ALPHA_BETA_SIGNALING Genes involved in Interferon alpha/beta signaling
0.0 0.3 REACTOME_CGMP_EFFECTS Genes involved in cGMP effects
0.0 1.3 REACTOME_FACTORS_INVOLVED_IN_MEGAKARYOCYTE_DEVELOPMENT_AND_PLATELET_PRODUCTION Genes involved in Factors involved in megakaryocyte development and platelet production