Motif ID: Foxf1

Z-value: 0.511


Transcription factors associated with Foxf1:

Gene SymbolEntrez IDGene Name
Foxf1 ENSMUSG00000042812.4 Foxf1

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Foxf1mm10_v2_chr8_+_121084352_121084474-0.096.1e-01Click!


Activity profile for motif Foxf1.

activity profile for motif Foxf1


Sorted Z-values histogram for motif Foxf1

Sorted Z-values for motif Foxf1



Network of associatons between targets according to the STRING database.



First level regulatory network of Foxf1

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr6_-_23248264 2.719 ENSMUST00000031709.5
 Fezf1
Fez family zinc finger 1
chr9_-_100506844 1.455 ENSMUST00000112874.3
 Nck1
non-catalytic region of tyrosine kinase adaptor protein 1
chr15_+_4375462 1.439 ENSMUST00000061925.4
 Plcxd3
phosphatidylinositol-specific phospholipase C, X domain containing 3
chr6_+_147032528 1.355 ENSMUST00000036194.4
 Rep15
RAB15 effector protein
chr4_-_36056726 1.349 ENSMUST00000108124.3
 Lingo2
leucine rich repeat and Ig domain containing 2
chr11_+_44617310 1.303 ENSMUST00000081265.5
ENSMUST00000101326.3
ENSMUST00000109268.1
 Ebf1


early B cell factor 1


chr16_+_81200697 1.246 ENSMUST00000067602.3
ENSMUST00000037785.7
 Ncam2

neural cell adhesion molecule 2

chr1_-_158814469 1.243 ENSMUST00000161589.2
 Pappa2
pappalysin 2
chr4_-_110290884 1.187 ENSMUST00000142722.1
 Elavl4
ELAV (embryonic lethal, abnormal vision, Drosophila)-like 4 (Hu antigen D)
chr1_+_66386968 1.169 ENSMUST00000145419.1
 Map2
microtubule-associated protein 2
chr2_-_79908428 1.141 ENSMUST00000102652.3
ENSMUST00000102651.3
 Pde1a

phosphodiesterase 1A, calmodulin-dependent

chr10_-_29535857 1.091 ENSMUST00000092623.3
 Rspo3
R-spondin 3 homolog (Xenopus laevis)
chr5_+_88583527 1.076 ENSMUST00000031229.6
 Rufy3
RUN and FYVE domain containing 3
chr17_+_29090969 1.022 ENSMUST00000119901.1
 Cdkn1a
cyclin-dependent kinase inhibitor 1A (P21)
chr13_-_41273977 0.990 ENSMUST00000163881.1
 Gm17364
predicted gene, 17364
chr7_+_113765998 0.968 ENSMUST00000046687.9
 Spon1
spondin 1, (f-spondin) extracellular matrix protein
chr6_+_5390387 0.962 ENSMUST00000183358.1
 Asb4
ankyrin repeat and SOCS box-containing 4
chr10_-_130280218 0.949 ENSMUST00000061571.3
 Neurod4
neurogenic differentiation 4
chr14_-_93888732 0.911 ENSMUST00000068992.2
 Pcdh9
protocadherin 9
chr8_+_45658666 0.872 ENSMUST00000134675.1
ENSMUST00000139869.1
ENSMUST00000126067.1
 Sorbs2


sorbin and SH3 domain containing 2



Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 81 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.5 2.7 GO:0021797 forebrain anterior/posterior pattern specification(GO:0021797)
0.1 2.7 GO:0003301 physiological muscle hypertrophy(GO:0003298) physiological cardiac muscle hypertrophy(GO:0003301) cell growth involved in cardiac muscle cell development(GO:0061049)
0.1 1.8 GO:0046069 cGMP catabolic process(GO:0046069)
0.0 1.8 GO:0050731 positive regulation of peptidyl-tyrosine phosphorylation(GO:0050731)
0.1 1.6 GO:0035881 amacrine cell differentiation(GO:0035881)
0.5 1.5 GO:0002191 cap-dependent translational initiation(GO:0002191)
0.0 1.5 GO:0060349 bone morphogenesis(GO:0060349)
0.2 1.4 GO:0060164 regulation of timing of neuron differentiation(GO:0060164)
0.1 1.4 GO:0033572 transferrin transport(GO:0033572)
0.0 1.3 GO:0051965 positive regulation of synapse assembly(GO:0051965)
0.0 1.2 GO:0007026 negative regulation of microtubule depolymerization(GO:0007026)
0.1 1.1 GO:0060670 branching involved in labyrinthine layer morphogenesis(GO:0060670)
0.1 1.1 GO:2000114 regulation of establishment of cell polarity(GO:2000114)
0.0 1.1 GO:0043488 regulation of mRNA stability(GO:0043488)
0.1 1.0 GO:0071493 cellular response to UV-B(GO:0071493)
0.1 1.0 GO:2001214 positive regulation of vasculogenesis(GO:2001214)
0.3 0.8 GO:0042320 regulation of circadian sleep/wake cycle, REM sleep(GO:0042320) circadian sleep/wake cycle, REM sleep(GO:0042747) positive regulation of circadian sleep/wake cycle, sleep(GO:0045938)
0.2 0.8 GO:1901731 positive regulation of platelet aggregation(GO:1901731)
0.1 0.8 GO:0006682 galactosylceramide biosynthetic process(GO:0006682) galactolipid biosynthetic process(GO:0019375)
0.2 0.7 GO:0060316 positive regulation of ryanodine-sensitive calcium-release channel activity(GO:0060316)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 28 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 3.4 GO:0031225 anchored component of membrane(GO:0031225)
0.1 1.8 GO:0071437 invadopodium(GO:0071437)
0.1 1.6 GO:0000164 protein phosphatase type 1 complex(GO:0000164)
0.1 1.2 GO:0097442 CA3 pyramidal cell dendrite(GO:0097442)
0.1 1.2 GO:0042788 polysomal ribosome(GO:0042788)
0.3 1.0 GO:0070557 PCNA-p21 complex(GO:0070557)
0.2 1.0 GO:0031466 Cul5-RING ubiquitin ligase complex(GO:0031466)
0.0 0.7 GO:0005640 nuclear outer membrane(GO:0005640)
0.0 0.7 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.0 0.6 GO:0097440 apical dendrite(GO:0097440)
0.0 0.5 GO:0000930 gamma-tubulin complex(GO:0000930)
0.0 0.5 GO:0001772 immunological synapse(GO:0001772)
0.1 0.4 GO:0034673 inhibin-betaglycan-ActRII complex(GO:0034673)
0.1 0.4 GO:0031262 Ndc80 complex(GO:0031262)
0.1 0.4 GO:0033503 HULC complex(GO:0033503)
0.0 0.4 GO:0031528 microvillus membrane(GO:0031528)
0.0 0.4 GO:1990635 proximal dendrite(GO:1990635)
0.1 0.3 GO:0001652 granular component(GO:0001652)
0.0 0.3 GO:0043034 costamere(GO:0043034)
0.0 0.2 GO:0044316 cone cell pedicle(GO:0044316)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 54 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.3 1.8 GO:0048101 calmodulin-dependent cyclic-nucleotide phosphodiesterase activity(GO:0004117) calcium- and calmodulin-regulated 3',5'-cyclic-GMP phosphodiesterase activity(GO:0048101)
0.2 1.5 GO:0071074 eukaryotic initiation factor eIF2 binding(GO:0071074)
0.0 1.5 GO:0008081 phosphoric diester hydrolase activity(GO:0008081)
0.0 1.5 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.0 1.5 GO:0005178 integrin binding(GO:0005178)
0.1 1.3 GO:0070742 C2H2 zinc finger domain binding(GO:0070742)
0.0 1.3 GO:0017091 AU-rich element binding(GO:0017091)
0.1 1.2 GO:0005519 cytoskeletal regulatory protein binding(GO:0005519)
0.0 1.1 GO:0005109 frizzled binding(GO:0005109)
0.3 1.0 GO:0019912 cyclin-dependent protein kinase activating kinase activity(GO:0019912)
0.0 0.9 GO:0008432 JUN kinase binding(GO:0008432)
0.2 0.8 GO:0047275 glucosaminylgalactosylglucosylceramide beta-galactosyltransferase activity(GO:0047275)
0.1 0.8 GO:0015250 water channel activity(GO:0015250)
0.0 0.8 GO:0071855 neuropeptide receptor binding(GO:0071855)
0.1 0.7 GO:0001206 transcriptional repressor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001206)
0.0 0.7 GO:0043495 protein anchor(GO:0043495)
0.0 0.7 GO:0019707 protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)
0.0 0.6 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
0.0 0.6 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.1 0.5 GO:0070915 lysophosphatidic acid receptor activity(GO:0070915)

Gene overrepresentation in C2:CP category:

Showing 1 to 8 of 8 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 3.7 PID_RET_PATHWAY Signaling events regulated by Ret tyrosine kinase
0.0 2.6 NABA_ECM_GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.1 1.0 SA_G2_AND_M_PHASES Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
0.0 1.0 ST_WNT_BETA_CATENIN_PATHWAY Wnt/beta-catenin Pathway
0.0 1.0 PID_LKB1_PATHWAY LKB1 signaling events
0.0 0.4 PID_HEDGEHOG_2PATHWAY Signaling events mediated by the Hedgehog family
0.0 0.4 PID_ARF6_DOWNSTREAM_PATHWAY Arf6 downstream pathway
0.0 0.4 PID_ALK1_PATHWAY ALK1 signaling events

Gene overrepresentation in C2:CP:REACTOME category:

Showing 1 to 20 of 22 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 2.0 REACTOME_SIGNALING_BY_RHO_GTPASES Genes involved in Signaling by Rho GTPases
0.1 1.8 REACTOME_CGMP_EFFECTS Genes involved in cGMP effects
0.0 1.7 REACTOME_NCAM1_INTERACTIONS Genes involved in NCAM1 interactions
0.1 1.5 REACTOME_ACTIVATION_OF_RAC Genes involved in Activation of Rac
0.1 1.2 REACTOME_REGULATION_OF_INSULIN_LIKE_GROWTH_FACTOR_IGF_ACTIVITY_BY_INSULIN_LIKE_GROWTH_FACTOR_BINDING_PROTEINS_IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.0 1.1 REACTOME_PEPTIDE_LIGAND_BINDING_RECEPTORS Genes involved in Peptide ligand-binding receptors
0.0 1.0 REACTOME_AKT_PHOSPHORYLATES_TARGETS_IN_THE_CYTOSOL Genes involved in AKT phosphorylates targets in the cytosol
0.0 0.7 REACTOME_DOWNREGULATION_OF_SMAD2_3_SMAD4_TRANSCRIPTIONAL_ACTIVITY Genes involved in Downregulation of SMAD2/3:SMAD4 transcriptional activity
0.0 0.6 REACTOME_SIGNALING_BY_NODAL Genes involved in Signaling by NODAL
0.0 0.6 REACTOME_SPHINGOLIPID_DE_NOVO_BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis
0.1 0.5 REACTOME_P2Y_RECEPTORS Genes involved in P2Y receptors
0.0 0.5 REACTOME_REGULATION_OF_KIT_SIGNALING Genes involved in Regulation of KIT signaling
0.0 0.5 REACTOME_DARPP_32_EVENTS Genes involved in DARPP-32 events
0.0 0.4 REACTOME_MYOGENESIS Genes involved in Myogenesis
0.0 0.3 REACTOME_TIE2_SIGNALING Genes involved in Tie2 Signaling
0.0 0.2 REACTOME_OLFACTORY_SIGNALING_PATHWAY Genes involved in Olfactory Signaling Pathway
0.0 0.2 REACTOME_REGULATION_OF_ORNITHINE_DECARBOXYLASE_ODC Genes involved in Regulation of ornithine decarboxylase (ODC)
0.0 0.2 REACTOME_RECEPTOR_LIGAND_BINDING_INITIATES_THE_SECOND_PROTEOLYTIC_CLEAVAGE_OF_NOTCH_RECEPTOR Genes involved in Receptor-ligand binding initiates the second proteolytic cleavage of Notch receptor
0.0 0.2 REACTOME_ABACAVIR_TRANSPORT_AND_METABOLISM Genes involved in Abacavir transport and metabolism
0.0 0.2 REACTOME_NEF_MEDIATED_DOWNREGULATION_OF_MHC_CLASS_I_COMPLEX_CELL_SURFACE_EXPRESSION Genes involved in Nef mediated downregulation of MHC class I complex cell surface expression