Motif ID: Foxg1

Z-value: 0.352


Transcription factors associated with Foxg1:

Gene SymbolEntrez IDGene Name
Foxg1 ENSMUSG00000020950.9 Foxg1

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Foxg1mm10_v2_chr12_+_49383007_49383105-0.421.0e-02Click!


Activity profile for motif Foxg1.

activity profile for motif Foxg1


Sorted Z-values histogram for motif Foxg1

Sorted Z-values for motif Foxg1



Network of associatons between targets according to the STRING database.



First level regulatory network of Foxg1

PNG image of the network

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Top targets:


Showing 1 to 20 of 52 entries
PromoterScoreRefseqGene SymbolGene Name
chr10_-_120476469 2.865 ENSMUST00000072777.7
ENSMUST00000159699.1
 Hmga2

high mobility group AT-hook 2

chr18_-_34007206 1.768 ENSMUST00000025234.5
 Epb4.1l4a
erythrocyte protein band 4.1-like 4a
chr2_-_57124003 1.762 ENSMUST00000112629.1
 Nr4a2
nuclear receptor subfamily 4, group A, member 2
chr15_-_85581809 1.315 ENSMUST00000023015.7
 Wnt7b
wingless-related MMTV integration site 7B
chr11_-_28583995 1.250 ENSMUST00000146385.2
 Ccdc85a
coiled-coil domain containing 85A
chr1_-_84284423 0.969 ENSMUST00000176720.1
 Pid1
phosphotyrosine interaction domain containing 1
chr13_-_3918157 0.705 ENSMUST00000091853.4
 Net1
neuroepithelial cell transforming gene 1
chr12_-_10900296 0.704 ENSMUST00000085735.2
 Pgk1-rs7
phosphoglycerate kinase-1, related sequence-7
chr3_-_127225847 0.683 ENSMUST00000182726.1
ENSMUST00000182779.1
 Ank2

ankyrin 2, brain

chr3_-_127225917 0.639 ENSMUST00000182064.1
ENSMUST00000182662.1
 Ank2

ankyrin 2, brain

chr18_+_11839220 0.637 ENSMUST00000171109.1
ENSMUST00000046948.8
 Cables1

CDK5 and Abl enzyme substrate 1

chr15_-_95528702 0.563 ENSMUST00000166170.1
 Nell2
NEL-like 2
chr9_-_60649793 0.549 ENSMUST00000053171.7
 Lrrc49
leucine rich repeat containing 49
chr15_-_95528228 0.525 ENSMUST00000075275.2
 Nell2
NEL-like 2
chr2_-_154558834 0.508 ENSMUST00000109716.2
ENSMUST00000000895.6
ENSMUST00000125793.1
 Necab3


N-terminal EF-hand calcium binding protein 3


chr9_+_91378636 0.444 ENSMUST00000066384.5
 Zic4
zinc finger protein of the cerebellum 4
chr5_-_142906702 0.397 ENSMUST00000167721.1
ENSMUST00000163829.1
ENSMUST00000100497.4
 Actb


actin, beta


chr14_-_121698417 0.395 ENSMUST00000040700.7
 Dock9
dedicator of cytokinesis 9
chr12_-_104751900 0.384 ENSMUST00000041987.6
 Dicer1
dicer 1, ribonuclease type III
chr16_-_28929658 0.373 ENSMUST00000100023.1
 Mb21d2
Mab-21 domain containing 2

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 21 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.3 2.9 GO:0060613 fat pad development(GO:0060613)
0.4 1.8 GO:0051866 general adaptation syndrome(GO:0051866)
0.4 1.3 GO:0016332 establishment or maintenance of polarity of embryonic epithelium(GO:0016332)
0.1 1.3 GO:0036371 protein localization to M-band(GO:0036309) protein localization to T-tubule(GO:0036371)
0.1 1.1 GO:0046543 development of secondary female sexual characteristics(GO:0046543)
0.2 1.0 GO:0070346 positive regulation of fat cell proliferation(GO:0070346) negative regulation of glucose import in response to insulin stimulus(GO:2001274)
0.0 0.7 GO:0051451 myoblast migration(GO:0051451)
0.1 0.5 GO:0046898 response to cycloheximide(GO:0046898)
0.1 0.5 GO:0042984 amyloid precursor protein biosynthetic process(GO:0042983) regulation of amyloid precursor protein biosynthetic process(GO:0042984)
0.1 0.4 GO:0098974 postsynaptic actin cytoskeleton organization(GO:0098974)
0.1 0.4 GO:0071335 hair follicle cell proliferation(GO:0071335)
0.1 0.4 GO:0070428 regulation of nucleotide-binding oligomerization domain containing signaling pathway(GO:0070424) regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway(GO:0070428) regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway(GO:0070432)
0.0 0.3 GO:0089711 L-glutamate transmembrane transport(GO:0089711)
0.0 0.3 GO:0090110 cargo loading into COPII-coated vesicle(GO:0090110)
0.0 0.3 GO:0001913 T cell mediated cytotoxicity(GO:0001913)
0.0 0.2 GO:0072272 proximal/distal pattern formation involved in metanephric nephron development(GO:0072272)
0.0 0.2 GO:0040032 post-embryonic body morphogenesis(GO:0040032)
0.0 0.2 GO:0043248 proteasome assembly(GO:0043248)
0.0 0.1 GO:0071896 protein localization to adherens junction(GO:0071896)
0.0 0.1 GO:0006102 isocitrate metabolic process(GO:0006102)

Gene overrepresentation in cellular_component category:

Showing 1 to 8 of 8 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 1.3 GO:0031430 M band(GO:0031430)
0.0 0.5 GO:0097136 Bcl-2 family protein complex(GO:0097136)
0.0 0.5 GO:0000137 Golgi cis cisterna(GO:0000137)
0.0 0.4 GO:0070578 RISC-loading complex(GO:0070578)
0.0 0.4 GO:0043189 NuA4 histone acetyltransferase complex(GO:0035267) H4/H2A histone acetyltransferase complex(GO:0043189) H4 histone acetyltransferase complex(GO:1902562)
0.1 0.3 GO:0089717 spanning component of plasma membrane(GO:0044214) spanning component of membrane(GO:0089717)
0.0 0.3 GO:0030127 COPII vesicle coat(GO:0030127)
0.0 0.2 GO:0043293 apoptosome(GO:0043293)

Gene overrepresentation in molecular_function category:

Showing 1 to 15 of 15 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.2 2.9 GO:0003680 AT DNA binding(GO:0003680)
0.1 1.8 GO:0035259 glucocorticoid receptor binding(GO:0035259)
0.3 1.3 GO:1902379 chemoattractant activity involved in axon guidance(GO:1902379)
0.0 1.3 GO:0030507 spectrin binding(GO:0030507)
0.0 1.1 GO:0005080 protein kinase C binding(GO:0005080)
0.0 0.7 GO:0017049 GTP-Rho binding(GO:0017049)
0.1 0.5 GO:0051434 BH3 domain binding(GO:0051434)
0.1 0.4 GO:0098973 structural constituent of synapse(GO:0098918) structural constituent of postsynaptic actin cytoskeleton(GO:0098973)
0.1 0.4 GO:0004525 ribonuclease III activity(GO:0004525) double-stranded RNA-specific ribonuclease activity(GO:0032296)
0.1 0.3 GO:0000099 sulfur amino acid transmembrane transporter activity(GO:0000099)
0.0 0.3 GO:0046703 natural killer cell lectin-like receptor binding(GO:0046703)
0.0 0.2 GO:0051429 corticotropin-releasing hormone receptor binding(GO:0051429) corticotropin-releasing hormone receptor 1 binding(GO:0051430)
0.0 0.2 GO:0097200 cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:0097200)
0.0 0.1 GO:0016309 1-phosphatidylinositol-5-phosphate 4-kinase activity(GO:0016309)
0.0 0.1 GO:0004449 isocitrate dehydrogenase (NAD+) activity(GO:0004449)

Gene overrepresentation in C2:CP category:

Showing 1 to 4 of 4 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 1.3 PID_WNT_SIGNALING_PATHWAY Wnt signaling network
0.0 1.0 PID_TAP63_PATHWAY Validated transcriptional targets of TAp63 isoforms
0.0 0.7 SA_PROGRAMMED_CELL_DEATH Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.
0.0 0.4 PID_CDC42_REG_PATHWAY Regulation of CDC42 activity

Gene overrepresentation in C2:CP:REACTOME category:

Showing 1 to 9 of 9 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 1.8 REACTOME_NUCLEAR_RECEPTOR_TRANSCRIPTION_PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.0 1.5 REACTOME_CLASS_B_2_SECRETIN_FAMILY_RECEPTORS Genes involved in Class B/2 (Secretin family receptors)
0.0 0.5 REACTOME_INFLAMMASOMES Genes involved in Inflammasomes
0.0 0.4 REACTOME_IRAK1_RECRUITS_IKK_COMPLEX Genes involved in IRAK1 recruits IKK complex
0.0 0.4 REACTOME_MICRORNA_MIRNA_BIOGENESIS Genes involved in MicroRNA (miRNA) Biogenesis
0.0 0.4 REACTOME_PREFOLDIN_MEDIATED_TRANSFER_OF_SUBSTRATE_TO_CCT_TRIC Genes involved in Prefoldin mediated transfer of substrate to CCT/TriC
0.0 0.3 REACTOME_ANTIGEN_PRESENTATION_FOLDING_ASSEMBLY_AND_PEPTIDE_LOADING_OF_CLASS_I_MHC Genes involved in Antigen Presentation: Folding, assembly and peptide loading of class I MHC
0.0 0.3 REACTOME_IMMUNOREGULATORY_INTERACTIONS_BETWEEN_A_LYMPHOID_AND_A_NON_LYMPHOID_CELL Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
0.0 0.2 REACTOME_ROLE_OF_DCC_IN_REGULATING_APOPTOSIS Genes involved in Role of DCC in regulating apoptosis