Motif ID: Foxk1_Foxj1

Z-value: 0.632

Transcription factors associated with Foxk1_Foxj1:

Gene SymbolEntrez IDGene Name
Foxj1 ENSMUSG00000034227.7 Foxj1
Foxk1 ENSMUSG00000056493.8 Foxk1

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Foxj1mm10_v2_chr11_-_116335384_1163353990.391.8e-02Click!
Foxk1mm10_v2_chr5_+_142401484_142401532-0.372.3e-02Click!





Network of associatons between targets according to the STRING database.



First level regulatory network of Foxk1_Foxj1

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr4_-_117178726 5.079 ENSMUST00000153953.1
ENSMUST00000106436.1
Kif2c

kinesin family member 2C

chr10_-_130280218 3.751 ENSMUST00000061571.3
Neurod4
neurogenic differentiation 4
chr10_-_92165159 3.671 ENSMUST00000182567.1
ENSMUST00000181604.2
ENSMUST00000181213.1
Rmst


rhabdomyosarcoma 2 associated transcript (non-coding RNA)


chr1_-_97977233 3.564 ENSMUST00000161567.1
Pam
peptidylglycine alpha-amidating monooxygenase
chr13_-_103920295 3.238 ENSMUST00000169083.1
Erbb2ip
Erbb2 interacting protein
chr3_-_100969644 2.740 ENSMUST00000076941.5
Ttf2
transcription termination factor, RNA polymerase II
chr3_+_159495408 2.729 ENSMUST00000120272.1
ENSMUST00000029825.7
ENSMUST00000106041.2
Depdc1a


DEP domain containing 1a


chr5_+_30666886 2.570 ENSMUST00000144742.1
Cenpa
centromere protein A
chr14_-_62456286 2.515 ENSMUST00000165651.1
ENSMUST00000022501.3
Gucy1b2

guanylate cyclase 1, soluble, beta 2

chr11_+_119022962 2.309 ENSMUST00000026662.7
Cbx2
chromobox 2
chr4_-_43499608 2.189 ENSMUST00000136005.1
ENSMUST00000054538.6
Arhgef39

Rho guanine nucleotide exchange factor (GEF) 39

chr10_+_127705170 2.175 ENSMUST00000079590.5
Myo1a
myosin IA
chr18_-_62756275 2.086 ENSMUST00000067450.1
ENSMUST00000048109.5
2700046A07Rik

RIKEN cDNA 2700046A07 gene

chr1_+_136467958 2.028 ENSMUST00000047817.6
Kif14
kinesin family member 14
chr9_-_100506844 1.980 ENSMUST00000112874.3
Nck1
non-catalytic region of tyrosine kinase adaptor protein 1
chr10_-_92164666 1.947 ENSMUST00000183123.1
ENSMUST00000182033.1
Rmst

rhabdomyosarcoma 2 associated transcript (non-coding RNA)

chr14_+_46832127 1.889 ENSMUST00000068532.8
Cgrrf1
cell growth regulator with ring finger domain 1
chr19_+_37376359 1.889 ENSMUST00000012587.3
Kif11
kinesin family member 11
chr15_+_57912199 1.779 ENSMUST00000022992.6
Tbc1d31
TBC1 domain family, member 31
chr8_-_53638945 1.711 ENSMUST00000047768.4
Neil3
nei like 3 (E. coli)
chr16_-_36784784 1.697 ENSMUST00000165531.1
Slc15a2
solute carrier family 15 (H+/peptide transporter), member 2
chr15_+_102459028 1.581 ENSMUST00000164938.1
ENSMUST00000023810.5
Prr13

proline rich 13

chr19_+_53329413 1.560 ENSMUST00000025998.7
Mxi1
Max interacting protein 1
chr5_+_92809372 1.530 ENSMUST00000113054.2
Shroom3
shroom family member 3
chr2_+_38511643 1.518 ENSMUST00000054234.3
ENSMUST00000112902.1
ENSMUST00000112895.1
Nek6


NIMA (never in mitosis gene a)-related expressed kinase 6


chr16_-_36784924 1.490 ENSMUST00000168279.1
ENSMUST00000164579.1
ENSMUST00000023616.2
Slc15a2


solute carrier family 15 (H+/peptide transporter), member 2


chr1_-_144177259 1.477 ENSMUST00000111941.1
ENSMUST00000052375.1
Rgs13

regulator of G-protein signaling 13

chr11_-_101466222 1.365 ENSMUST00000040430.7
Vat1
vesicle amine transport protein 1 homolog (T californica)
chr12_+_71016658 1.349 ENSMUST00000125125.1
Arid4a
AT rich interactive domain 4A (RBP1-like)
chr12_-_31950170 1.345 ENSMUST00000176520.1
Hbp1
high mobility group box transcription factor 1
chr12_-_31950210 1.323 ENSMUST00000176084.1
ENSMUST00000176103.1
ENSMUST00000167458.2
Hbp1


high mobility group box transcription factor 1


chr15_+_25752860 1.242 ENSMUST00000022882.5
ENSMUST00000135173.1
Myo10

myosin X

chr2_+_119047116 1.239 ENSMUST00000152380.1
ENSMUST00000099542.2
Casc5

cancer susceptibility candidate 5

chr3_+_131110350 1.235 ENSMUST00000066849.6
ENSMUST00000106341.2
ENSMUST00000029611.7
Lef1


lymphoid enhancer binding factor 1


chr1_-_139377041 1.233 ENSMUST00000059825.5
Crb1
crumbs homolog 1 (Drosophila)
chr14_+_73237891 1.203 ENSMUST00000044405.6
Lpar6
lysophosphatidic acid receptor 6
chr4_+_11704439 1.199 ENSMUST00000108304.2
Gem
GTP binding protein (gene overexpressed in skeletal muscle)
chr8_+_34807287 1.182 ENSMUST00000033930.4
Dusp4
dual specificity phosphatase 4
chr19_+_5406815 1.181 ENSMUST00000174412.1
ENSMUST00000153017.2
4930481A15Rik

RIKEN cDNA 4930481A15 gene

chr19_-_58455161 1.141 ENSMUST00000135730.1
ENSMUST00000152507.1
Gfra1

glial cell line derived neurotrophic factor family receptor alpha 1

chrX_+_9885622 1.126 ENSMUST00000067529.2
ENSMUST00000086165.3
Sytl5

synaptotagmin-like 5

chr5_-_44099220 1.113 ENSMUST00000165909.1
Prom1
prominin 1
chr8_-_110902442 1.112 ENSMUST00000041382.6
Fuk
fucokinase
chr1_-_156034800 1.080 ENSMUST00000169241.1
Tor1aip1
torsin A interacting protein 1
chr11_-_34833631 1.071 ENSMUST00000093191.2
Spdl1
spindle apparatus coiled-coil protein 1
chr15_+_102459193 1.070 ENSMUST00000164957.1
ENSMUST00000171245.1
Prr13

proline rich 13

chr2_+_177508570 1.068 ENSMUST00000108940.2
Gm14403
predicted gene 14403
chr2_+_143915273 1.067 ENSMUST00000103172.3
Dstn
destrin
chr14_+_47472628 1.049 ENSMUST00000095941.2
Fbxo34
F-box protein 34
chr10_+_73821857 1.021 ENSMUST00000177128.1
ENSMUST00000064562.7
ENSMUST00000129404.2
ENSMUST00000105426.3
ENSMUST00000131321.2
ENSMUST00000126920.2
ENSMUST00000147189.2
ENSMUST00000105424.3
ENSMUST00000092420.6
ENSMUST00000105429.3
ENSMUST00000131724.2
ENSMUST00000152655.2
ENSMUST00000151116.2
ENSMUST00000155701.2
ENSMUST00000152819.2
ENSMUST00000125517.2
ENSMUST00000124046.1
ENSMUST00000149977.2
ENSMUST00000146682.1
ENSMUST00000177107.1
Pcdh15



















protocadherin 15



















chr14_-_62454793 1.015 ENSMUST00000128573.1
Gucy1b2
guanylate cyclase 1, soluble, beta 2
chr2_+_119047129 1.004 ENSMUST00000153300.1
ENSMUST00000028799.5
Casc5

cancer susceptibility candidate 5

chr2_-_170194033 0.984 ENSMUST00000180625.1
Gm17619
predicted gene, 17619
chr14_-_57826128 0.929 ENSMUST00000022536.2
Ska3
spindle and kinetochore associated complex subunit 3
chr1_+_110099295 0.915 ENSMUST00000134301.1
Cdh7
cadherin 7, type 2
chr8_-_61902669 0.883 ENSMUST00000121785.1
ENSMUST00000034057.7
Palld

palladin, cytoskeletal associated protein

chr7_-_52005792 0.869 ENSMUST00000098414.3
Svip
small VCP/p97-interacting protein
chr10_-_13324160 0.856 ENSMUST00000105545.4
Phactr2
phosphatase and actin regulator 2
chr1_-_139377094 0.845 ENSMUST00000131586.1
ENSMUST00000145244.1
Crb1

crumbs homolog 1 (Drosophila)

chr4_+_11558914 0.835 ENSMUST00000178703.1
ENSMUST00000095145.5
ENSMUST00000108306.2
ENSMUST00000070755.6
Rad54b



RAD54 homolog B (S. cerevisiae)



chr11_-_86993682 0.826 ENSMUST00000018571.4
Ypel2
yippee-like 2 (Drosophila)
chr19_-_58455903 0.816 ENSMUST00000131877.1
Gfra1
glial cell line derived neurotrophic factor family receptor alpha 1
chr16_+_42907563 0.812 ENSMUST00000151244.1
ENSMUST00000114694.2
Zbtb20

zinc finger and BTB domain containing 20

chr6_-_6217023 0.810 ENSMUST00000015256.8
Slc25a13
solute carrier family 25 (mitochondrial carrier, adenine nucleotide translocator), member 13
chr4_-_34882919 0.803 ENSMUST00000098163.2
ENSMUST00000047950.5
Zfp292

zinc finger protein 292

chr1_-_156034826 0.799 ENSMUST00000141878.1
ENSMUST00000123705.1
Tor1aip1

torsin A interacting protein 1

chr1_+_20917856 0.796 ENSMUST00000167119.1
Paqr8
progestin and adipoQ receptor family member VIII
chr12_-_31950535 0.794 ENSMUST00000172314.2
Hbp1
high mobility group box transcription factor 1
chr10_-_128180265 0.787 ENSMUST00000099139.1
Rbms2
RNA binding motif, single stranded interacting protein 2
chr4_+_11191354 0.784 ENSMUST00000170901.1
Ccne2
cyclin E2
chr18_+_34759551 0.784 ENSMUST00000097622.3
Fam53c
family with sequence similarity 53, member C
chr12_-_84617326 0.782 ENSMUST00000021666.4
Abcd4
ATP-binding cassette, sub-family D (ALD), member 4
chr3_+_94933041 0.772 ENSMUST00000090839.5
Selenbp1
selenium binding protein 1
chr14_+_47472547 0.750 ENSMUST00000168833.1
ENSMUST00000163324.1
ENSMUST00000043112.7
Fbxo34


F-box protein 34


chr1_+_153749414 0.743 ENSMUST00000086209.3
Rnasel
ribonuclease L (2', 5'-oligoisoadenylate synthetase-dependent)
chr5_+_139423151 0.743 ENSMUST00000066211.4
Gper1
G protein-coupled estrogen receptor 1
chr10_+_88091070 0.736 ENSMUST00000048621.7
Pmch
pro-melanin-concentrating hormone
chrX_-_166510424 0.701 ENSMUST00000112188.1
Tceanc
transcription elongation factor A (SII) N-terminal and central domain containing
chr14_+_32028989 0.700 ENSMUST00000022460.4
Galnt15
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 15
chrM_-_14060 0.673 ENSMUST00000082419.1
mt-Nd6
mitochondrially encoded NADH dehydrogenase 6
chr9_+_53850243 0.672 ENSMUST00000048485.5
Sln
sarcolipin
chr1_-_120120138 0.661 ENSMUST00000112648.1
ENSMUST00000128408.1
Dbi

diazepam binding inhibitor

chr7_+_80186835 0.657 ENSMUST00000107383.1
ENSMUST00000032754.7
Sema4b

sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B

chr10_+_96616998 0.657 ENSMUST00000038377.7
Btg1
B cell translocation gene 1, anti-proliferative
chrX_+_139217166 0.656 ENSMUST00000166444.1
ENSMUST00000170671.1
ENSMUST00000113041.2
ENSMUST00000113042.2
Mum1l1



melanoma associated antigen (mutated) 1-like 1



chr2_+_61578549 0.653 ENSMUST00000112502.1
ENSMUST00000078074.2
Tank

TRAF family member-associated Nf-kappa B activator

chr17_+_78491549 0.647 ENSMUST00000079363.4
Gm10093
predicted pseudogene 10093
chr14_+_120275669 0.622 ENSMUST00000088419.6
ENSMUST00000167459.1
Mbnl2

muscleblind-like 2

chr9_+_118506226 0.617 ENSMUST00000084820.4
Golga4
golgi autoantigen, golgin subfamily a, 4
chr2_+_102706356 0.617 ENSMUST00000123759.1
ENSMUST00000111212.1
ENSMUST00000005220.4
Slc1a2


solute carrier family 1 (glial high affinity glutamate transporter), member 2


chr15_-_3995708 0.615 ENSMUST00000046633.8
AW549877
expressed sequence AW549877
chr17_-_26095487 0.606 ENSMUST00000025007.5
Nme4
NME/NM23 nucleoside diphosphate kinase 4
chr2_+_73312601 0.600 ENSMUST00000090811.4
ENSMUST00000112050.1
Scrn3

secernin 3

chr10_-_37138863 0.600 ENSMUST00000092584.5
Marcks
myristoylated alanine rich protein kinase C substrate
chr14_+_30879257 0.598 ENSMUST00000040715.6
Mustn1
musculoskeletal, embryonic nuclear protein 1
chr19_-_34879452 0.574 ENSMUST00000036584.5
Pank1
pantothenate kinase 1
chr1_-_75046639 0.564 ENSMUST00000152855.1
Nhej1
nonhomologous end-joining factor 1
chr9_-_105521147 0.557 ENSMUST00000176770.1
ENSMUST00000085133.6
Atp2c1

ATPase, Ca++-sequestering

chr3_+_5218516 0.556 ENSMUST00000175866.1
Zfhx4
zinc finger homeodomain 4
chr2_+_62664279 0.551 ENSMUST00000028257.2
Gca
grancalcin
chr9_+_114731177 0.543 ENSMUST00000035007.8
Cmtm6
CKLF-like MARVEL transmembrane domain containing 6
chr4_-_108833544 0.541 ENSMUST00000102740.1
ENSMUST00000102741.1
Btf3l4

basic transcription factor 3-like 4

chr6_-_71144338 0.537 ENSMUST00000074241.7
ENSMUST00000160918.1
Thnsl2

threonine synthase-like 2 (bacterial)

chr9_-_60511003 0.536 ENSMUST00000098660.3
Thsd4
thrombospondin, type I, domain containing 4
chr5_+_150522599 0.536 ENSMUST00000044620.7
Brca2
breast cancer 2
chr13_-_83729544 0.534 ENSMUST00000181705.1
Gm26803
predicted gene, 26803
chr2_+_79635416 0.533 ENSMUST00000111788.1
Ssfa2
sperm specific antigen 2
chr12_-_84400929 0.532 ENSMUST00000122194.1
Entpd5
ectonucleoside triphosphate diphosphohydrolase 5
chr2_+_52038005 0.531 ENSMUST00000065927.5
Tnfaip6
tumor necrosis factor alpha induced protein 6
chr3_-_103791537 0.531 ENSMUST00000118317.1
Hipk1
homeodomain interacting protein kinase 1
chr2_+_91256144 0.528 ENSMUST00000154959.1
ENSMUST00000059566.4
Pacsin3

protein kinase C and casein kinase substrate in neurons 3

chr12_+_71136848 0.522 ENSMUST00000149564.1
ENSMUST00000045907.8
2700049A03Rik

RIKEN cDNA 2700049A03 gene

chr9_-_65908676 0.520 ENSMUST00000119245.1
ENSMUST00000134338.1
ENSMUST00000179395.1
Trip4


thyroid hormone receptor interactor 4


chr2_+_4718145 0.511 ENSMUST00000056914.6
Bend7
BEN domain containing 7
chr12_-_84400851 0.507 ENSMUST00000117286.1
Entpd5
ectonucleoside triphosphate diphosphohydrolase 5
chr2_+_164486455 0.506 ENSMUST00000069385.8
ENSMUST00000143690.1
Dbndd2

dysbindin (dystrobrevin binding protein 1) domain containing 2

chr9_+_96258697 0.501 ENSMUST00000179416.1
Tfdp2
transcription factor Dp 2
chr7_-_97417730 0.498 ENSMUST00000043077.7
Thrsp
thyroid hormone responsive
chr2_-_181578906 0.492 ENSMUST00000136875.1
Uckl1
uridine-cytidine kinase 1-like 1
chr15_-_65014904 0.489 ENSMUST00000110100.2
Gm21961
predicted gene, 21961
chr6_+_42264983 0.484 ENSMUST00000031895.6
Casp2
caspase 2
chr10_+_25408346 0.479 ENSMUST00000092645.6
Epb4.1l2
erythrocyte protein band 4.1-like 2
chr1_-_119913162 0.479 ENSMUST00000037906.5
Tmem177
transmembrane protein 177
chr1_+_165769392 0.475 ENSMUST00000040298.4
Creg1
cellular repressor of E1A-stimulated genes 1
chr1_-_58504946 0.467 ENSMUST00000027198.5
Orc2
origin recognition complex, subunit 2
chr4_-_154097105 0.466 ENSMUST00000105643.1
ENSMUST00000133533.1
ENSMUST00000097762.4
Trp73


transformation related protein 73


chrX_+_142227923 0.463 ENSMUST00000042329.5
Nxt2
nuclear transport factor 2-like export factor 2
chr10_+_37139558 0.463 ENSMUST00000062667.3
5930403N24Rik
RIKEN cDNA 5930403N24 gene
chr2_-_91255995 0.461 ENSMUST00000180732.1
Gm17281
predicted gene, 17281
chrX_+_102119447 0.461 ENSMUST00000113627.3
Pin4
protein (peptidyl-prolyl cis/trans isomerase) NIMA-interacting, 4 (parvulin)
chr8_+_94214567 0.458 ENSMUST00000079961.6
Nup93
nucleoporin 93
chr7_+_64287665 0.457 ENSMUST00000032736.4
Mtmr10
myotubularin related protein 10
chr1_-_45503282 0.454 ENSMUST00000086430.4
Col5a2
collagen, type V, alpha 2
chr2_+_27676440 0.441 ENSMUST00000129514.1
Rxra
retinoid X receptor alpha
chr7_+_140968028 0.440 ENSMUST00000106040.1
ENSMUST00000026564.8
Ifitm1

interferon induced transmembrane protein 1

chrX_-_10117597 0.440 ENSMUST00000115543.2
ENSMUST00000044789.3
ENSMUST00000115544.2
Srpx


sushi-repeat-containing protein


chrX_+_7722267 0.439 ENSMUST00000125991.1
ENSMUST00000148624.1
Wdr45

WD repeat domain 45

chr9_-_60838200 0.437 ENSMUST00000063858.7
Gm9869
predicted gene 9869
chr8_-_70523085 0.435 ENSMUST00000137610.1
ENSMUST00000121623.1
ENSMUST00000093456.5
ENSMUST00000118850.1
Kxd1



KxDL motif containing 1



chr18_+_67800101 0.435 ENSMUST00000025425.5
Cep192
centrosomal protein 192
chr7_+_31059342 0.435 ENSMUST00000039775.7
Lgi4
leucine-rich repeat LGI family, member 4
chr10_+_115569986 0.421 ENSMUST00000173620.1
A930009A15Rik
RIKEN cDNA A930009A15 gene
chr11_-_58801944 0.408 ENSMUST00000094156.4
ENSMUST00000060581.3
Fam183b

family with sequence similarity 183, member B

chr10_-_127522428 0.406 ENSMUST00000026470.4
Shmt2
serine hydroxymethyltransferase 2 (mitochondrial)
chr4_-_44710408 0.406 ENSMUST00000134968.2
ENSMUST00000173821.1
ENSMUST00000174319.1
ENSMUST00000173733.1
ENSMUST00000172866.1
ENSMUST00000165417.2
ENSMUST00000107825.2
ENSMUST00000102932.3
ENSMUST00000107827.2
ENSMUST00000107826.2
Pax5









paired box gene 5









chr10_-_14718191 0.404 ENSMUST00000020016.4
Gje1
gap junction protein, epsilon 1
chr2_+_32535315 0.402 ENSMUST00000133512.1
ENSMUST00000048375.5
Fam102a

family with sequence similarity 102, member A

chr15_+_102460076 0.399 ENSMUST00000164688.1
Prr13
proline rich 13
chrX_+_170010744 0.396 ENSMUST00000178789.1
Gm21887
predicted gene, 21887
chr13_+_35659856 0.394 ENSMUST00000075220.6
Cdyl
chromodomain protein, Y chromosome-like
chr6_-_120357342 0.390 ENSMUST00000163827.1
Ccdc77
coiled-coil domain containing 77
chr2_+_91255954 0.390 ENSMUST00000134699.1
Pacsin3
protein kinase C and casein kinase substrate in neurons 3
chr15_-_50882806 0.387 ENSMUST00000184885.1
Trps1
trichorhinophalangeal syndrome I (human)
chr18_+_35598607 0.386 ENSMUST00000041314.8
ENSMUST00000115737.1
ENSMUST00000115736.1
ENSMUST00000115735.1
Paip2



polyadenylate-binding protein-interacting protein 2



chr10_+_18469958 0.378 ENSMUST00000162891.1
ENSMUST00000100054.3
Nhsl1

NHS-like 1

chr11_+_114851142 0.375 ENSMUST00000133245.1
ENSMUST00000122967.2
Gprc5c

G protein-coupled receptor, family C, group 5, member C

chr10_+_21377290 0.373 ENSMUST00000042699.7
ENSMUST00000159163.1
Aldh8a1

aldehyde dehydrogenase 8 family, member A1

chr5_-_5664196 0.360 ENSMUST00000061008.3
ENSMUST00000054865.6
A330021E22Rik

RIKEN cDNA A330021E22 gene

chr3_-_30793549 0.359 ENSMUST00000180833.1
4933429H19Rik
RIKEN cDNA 4933429H19 gene
chrX_-_100626568 0.357 ENSMUST00000015812.5
Pdzd11
PDZ domain containing 11
chr14_-_8318023 0.355 ENSMUST00000120411.1
Fam107a
family with sequence similarity 107, member A
chr5_-_31526693 0.355 ENSMUST00000118874.1
ENSMUST00000117642.1
ENSMUST00000065388.4
Supt7l


suppressor of Ty 7-like


chr11_+_23665615 0.354 ENSMUST00000109525.1
ENSMUST00000020520.4
Pus10

pseudouridylate synthase 10

chr12_-_4689926 0.339 ENSMUST00000080062.6
Gm17541
predicted gene, 17541
chr10_+_11281304 0.338 ENSMUST00000129456.1
Fbxo30
F-box protein 30
chr12_+_112999964 0.336 ENSMUST00000180971.1
9230104M06Rik
RIKEN cDNA 9230104M06 gene
chr5_-_122697603 0.333 ENSMUST00000071235.4
Gm10064
predicted gene 10064
chr5_+_110330697 0.325 ENSMUST00000112481.1
Pole
polymerase (DNA directed), epsilon
chr14_-_105177263 0.324 ENSMUST00000163499.1
Rbm26
RNA binding motif protein 26
chr11_+_46235460 0.322 ENSMUST00000060185.2
Fndc9
fibronectin type III domain containing 9
chr11_-_107131922 0.318 ENSMUST00000057892.8
Bptf
bromodomain PHD finger transcription factor
chr3_+_94398517 0.317 ENSMUST00000050975.3
Lingo4
leucine rich repeat and Ig domain containing 4
chr4_+_154869585 0.315 ENSMUST00000079269.7
ENSMUST00000163732.1
ENSMUST00000080559.6
Mmel1


membrane metallo-endopeptidase-like 1


chr12_-_3357012 0.314 ENSMUST00000180719.1
Gm26520
predicted gene, 26520
chr14_-_105177280 0.313 ENSMUST00000100327.3
ENSMUST00000022715.7
Rbm26

RNA binding motif protein 26

chr2_+_163661495 0.313 ENSMUST00000135537.1
Pkig
protein kinase inhibitor, gamma
chr17_+_47649621 0.312 ENSMUST00000145314.1
Usp49
ubiquitin specific peptidase 49
chr5_+_122209729 0.311 ENSMUST00000072602.7
ENSMUST00000143560.1
Hvcn1

hydrogen voltage-gated channel 1

chr3_+_32397671 0.310 ENSMUST00000108243.1
Pik3ca
phosphatidylinositol 3-kinase, catalytic, alpha polypeptide
chr11_+_69622024 0.309 ENSMUST00000108656.2
ENSMUST00000092969.1
Sat2

spermidine/spermine N1-acetyl transferase 2

chr10_-_62792243 0.309 ENSMUST00000020268.5
Ccar1
cell division cycle and apoptosis regulator 1
chr4_-_82850721 0.308 ENSMUST00000139401.1
Zdhhc21
zinc finger, DHHC domain containing 21
chr9_+_45055166 0.306 ENSMUST00000114664.1
ENSMUST00000093856.3
Mpzl3

myelin protein zero-like 3

chr8_-_8690493 0.305 ENSMUST00000048545.8
Arglu1
arginine and glutamate rich 1
chr4_-_87806296 0.305 ENSMUST00000126353.1
ENSMUST00000149357.1
Mllt3

myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 3

chr3_+_60501252 0.304 ENSMUST00000099087.2
Mbnl1
muscleblind-like 1 (Drosophila)
chr7_+_90426312 0.297 ENSMUST00000061391.7
Ccdc89
coiled-coil domain containing 89
chr7_-_133123409 0.294 ENSMUST00000170459.1
ENSMUST00000166400.1
Ctbp2

C-terminal binding protein 2

chr5_+_48242549 0.294 ENSMUST00000172493.1
Slit2
slit homolog 2 (Drosophila)
chr10_+_17796256 0.294 ENSMUST00000037964.6
Txlnb
taxilin beta
chrY_+_90785442 0.293 ENSMUST00000177591.1
ENSMUST00000177671.1
ENSMUST00000179077.1
Erdr1


erythroid differentiation regulator 1


chr4_-_82885148 0.290 ENSMUST00000048430.3
Cer1
cerberus 1 homolog (Xenopus laevis)
chr17_+_46496753 0.287 ENSMUST00000046497.6
Dnph1
2'-deoxynucleoside 5'-phosphate N-hydrolase 1
chr6_+_29361410 0.285 ENSMUST00000156163.1
Calu
calumenin
chr2_-_106970391 0.282 ENSMUST00000093883.3
Arl14ep
ADP-ribosylation factor-like 14 effector protein
chr18_+_34758890 0.277 ENSMUST00000049281.5
Fam53c
family with sequence similarity 53, member C
chr14_+_52110939 0.277 ENSMUST00000111600.4
Rpgrip1
retinitis pigmentosa GTPase regulator interacting protein 1
chr2_+_177768044 0.275 ENSMUST00000108942.3
Gm14322
predicted gene 14322
chr17_-_79896028 0.270 ENSMUST00000068282.5
ENSMUST00000112437.1
Atl2

atlastin GTPase 2

chr3_+_67374091 0.269 ENSMUST00000077916.5
Mlf1
myeloid leukemia factor 1

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
1.0 5.1 GO:0030951 establishment or maintenance of microtubule cytoskeleton polarity(GO:0030951)
0.7 2.0 GO:0002191 cap-dependent translational initiation(GO:0002191)
0.6 3.2 GO:0042891 antibiotic transport(GO:0042891) dipeptide transport(GO:0042938)
0.5 2.0 GO:0021698 cerebellar cortex structural organization(GO:0021698)
0.4 1.2 GO:0032696 negative regulation of interleukin-13 production(GO:0032696) trachea submucosa development(GO:0061152) trachea gland development(GO:0061153) odontoblast differentiation(GO:0071895) regulation of estrogen receptor binding(GO:0071898) negative regulation of estrogen receptor binding(GO:0071899)
0.4 3.5 GO:0010745 negative regulation of macrophage derived foam cell differentiation(GO:0010745)
0.4 1.1 GO:0072139 glomerular parietal epithelial cell differentiation(GO:0072139)
0.3 3.6 GO:0009404 toxin metabolic process(GO:0009404)
0.3 3.8 GO:0035881 amacrine cell differentiation(GO:0035881)
0.3 1.1 GO:0046368 GDP-L-fucose metabolic process(GO:0046368)
0.3 1.4 GO:0010637 negative regulation of mitochondrial fusion(GO:0010637)
0.3 0.8 GO:1903070 negative regulation of ER-associated ubiquitin-dependent protein catabolic process(GO:1903070)
0.3 1.1 GO:0030043 actin filament fragmentation(GO:0030043)
0.3 2.6 GO:0071763 nuclear membrane organization(GO:0071763)
0.2 0.7 GO:0042320 regulation of circadian sleep/wake cycle, REM sleep(GO:0042320) circadian sleep/wake cycle, REM sleep(GO:0042747) positive regulation of circadian sleep/wake cycle, sleep(GO:0045938)
0.2 1.3 GO:0034773 histone H4-K20 trimethylation(GO:0034773) establishment of Sertoli cell barrier(GO:0097368)
0.2 3.6 GO:0071459 protein localization to chromosome, centromeric region(GO:0071459)
0.2 1.9 GO:0046602 regulation of mitotic centrosome separation(GO:0046602)
0.2 0.5 GO:0006566 threonine metabolic process(GO:0006566)
0.2 0.7 GO:1901894 regulation of calcium-transporting ATPase activity(GO:1901894)
0.2 0.7 GO:2000158 positive regulation of ubiquitin-specific protease activity(GO:2000158)
0.2 0.9 GO:0009235 cobalamin metabolic process(GO:0009235)
0.2 0.5 GO:1903225 negative regulation of endodermal cell differentiation(GO:1903225)
0.1 0.4 GO:0060244 negative regulation of cell proliferation involved in contact inhibition(GO:0060244)
0.1 0.6 GO:0055071 cellular manganese ion homeostasis(GO:0030026) Golgi calcium ion homeostasis(GO:0032468) manganese ion homeostasis(GO:0055071)
0.1 2.7 GO:0006353 DNA-templated transcription, termination(GO:0006353)
0.1 0.4 GO:0006545 glycine biosynthetic process(GO:0006545)
0.1 0.5 GO:0051311 meiotic metaphase plate congression(GO:0051311) attachment of spindle microtubules to kinetochore involved in meiotic chromosome segregation(GO:0051316)
0.1 0.7 GO:0036151 phosphatidylcholine acyl-chain remodeling(GO:0036151)
0.1 0.8 GO:0035234 ectopic germ cell programmed cell death(GO:0035234)
0.1 0.6 GO:0070779 D-aspartate transport(GO:0070777) D-aspartate import(GO:0070779)
0.1 1.2 GO:1901386 negative regulation of voltage-gated calcium channel activity(GO:1901386)
0.1 0.6 GO:1902732 positive regulation of chondrocyte proliferation(GO:1902732)
0.1 0.5 GO:0033326 cerebrospinal fluid secretion(GO:0033326)
0.1 1.0 GO:0050957 equilibrioception(GO:0050957)
0.1 0.4 GO:0043490 malate-aspartate shuttle(GO:0043490)
0.1 0.7 GO:2000271 positive regulation of fibroblast apoptotic process(GO:2000271)
0.1 0.3 GO:0045004 DNA replication proofreading(GO:0045004)
0.1 0.3 GO:0044028 DNA hypomethylation(GO:0044028) hypomethylation of CpG island(GO:0044029)
0.1 0.3 GO:0032918 polyamine acetylation(GO:0032917) spermidine acetylation(GO:0032918)
0.1 2.2 GO:0030033 microvillus assembly(GO:0030033)
0.1 0.5 GO:0008655 pyrimidine-containing compound salvage(GO:0008655) pyrimidine nucleoside salvage(GO:0043097)
0.1 0.3 GO:0021972 corticospinal neuron axon guidance through spinal cord(GO:0021972) positive regulation of negative chemotaxis(GO:0050924) induction of negative chemotaxis(GO:0050929) negative regulation of mononuclear cell migration(GO:0071676) negative regulation of retinal ganglion cell axon guidance(GO:0090260)
0.1 0.3 GO:1900108 negative regulation of nodal signaling pathway(GO:1900108)
0.1 3.6 GO:0006182 cGMP biosynthetic process(GO:0006182)
0.1 0.4 GO:0042905 9-cis-retinoic acid biosynthetic process(GO:0042904) 9-cis-retinoic acid metabolic process(GO:0042905)
0.1 0.4 GO:0006447 regulation of translational initiation by iron(GO:0006447) positive regulation of translational initiation by iron(GO:0045994)
0.1 0.4 GO:0010990 regulation of SMAD protein complex assembly(GO:0010990)
0.1 1.2 GO:0035970 peptidyl-threonine dephosphorylation(GO:0035970)
0.1 2.5 GO:0042462 eye photoreceptor cell development(GO:0042462)
0.1 0.4 GO:1903361 protein localization to basolateral plasma membrane(GO:1903361)
0.1 0.2 GO:0097309 cap1 mRNA methylation(GO:0097309)
0.1 0.7 GO:0006228 UTP biosynthetic process(GO:0006228)
0.1 0.3 GO:0035616 histone H2B conserved C-terminal lysine deubiquitination(GO:0035616)
0.1 0.2 GO:0042117 monocyte activation(GO:0042117)
0.1 0.2 GO:0070125 mitochondrial translational elongation(GO:0070125)
0.1 0.5 GO:0048251 elastic fiber assembly(GO:0048251)
0.1 0.5 GO:0002318 myeloid progenitor cell differentiation(GO:0002318)
0.1 1.2 GO:0051482 positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G-protein coupled signaling pathway(GO:0051482)
0.1 0.3 GO:0090521 glomerular visceral epithelial cell migration(GO:0090521)
0.1 0.2 GO:0006547 histidine metabolic process(GO:0006547) imidazole-containing compound catabolic process(GO:0052805)
0.1 0.9 GO:2001275 positive regulation of glucose import in response to insulin stimulus(GO:2001275)
0.1 0.5 GO:0048386 positive regulation of retinoic acid receptor signaling pathway(GO:0048386)
0.1 0.3 GO:0034587 piRNA metabolic process(GO:0034587)
0.1 0.1 GO:1902071 regulation of hypoxia-inducible factor-1alpha signaling pathway(GO:1902071)
0.1 0.3 GO:0071294 cellular response to zinc ion(GO:0071294)
0.1 0.1 GO:0051541 elastin metabolic process(GO:0051541)
0.1 0.2 GO:1903774 positive regulation of viral budding via host ESCRT complex(GO:1903774)
0.0 0.2 GO:0018242 protein O-linked glycosylation via serine(GO:0018242)
0.0 0.7 GO:0034497 protein localization to pre-autophagosomal structure(GO:0034497)
0.0 0.9 GO:0051044 positive regulation of membrane protein ectodomain proteolysis(GO:0051044)
0.0 0.1 GO:2000836 luteinizing hormone secretion(GO:0032275) positive regulation of androgen secretion(GO:2000836) positive regulation of testosterone secretion(GO:2000845)
0.0 0.4 GO:0097475 motor neuron migration(GO:0097475)
0.0 0.2 GO:0051611 negative regulation of neurotransmitter uptake(GO:0051581) serotonin uptake(GO:0051610) regulation of serotonin uptake(GO:0051611) negative regulation of serotonin uptake(GO:0051612)
0.0 0.1 GO:0003032 detection of oxygen(GO:0003032)
0.0 0.2 GO:0033762 response to glucagon(GO:0033762)
0.0 0.1 GO:1904719 excitatory chemical synaptic transmission(GO:0098976) positive regulation of AMPA glutamate receptor clustering(GO:1904719)
0.0 0.1 GO:0019732 antifungal humoral response(GO:0019732) antifungal innate immune response(GO:0061760) regulation of antifungal innate immune response(GO:1905034) negative regulation of antifungal innate immune response(GO:1905035)
0.0 0.8 GO:0071803 positive regulation of podosome assembly(GO:0071803)
0.0 0.2 GO:0031022 nuclear migration along microfilament(GO:0031022)
0.0 1.0 GO:0051084 'de novo' posttranslational protein folding(GO:0051084)
0.0 0.1 GO:0021933 radial glia guided migration of cerebellar granule cell(GO:0021933)
0.0 0.2 GO:2000210 positive regulation of anoikis(GO:2000210)
0.0 0.5 GO:0061072 embryonic retina morphogenesis in camera-type eye(GO:0060059) iris morphogenesis(GO:0061072)
0.0 0.2 GO:0034393 positive regulation of smooth muscle cell apoptotic process(GO:0034393)
0.0 1.7 GO:0006284 base-excision repair(GO:0006284)
0.0 2.0 GO:0030071 regulation of mitotic metaphase/anaphase transition(GO:0030071) regulation of metaphase/anaphase transition of cell cycle(GO:1902099)
0.0 0.1 GO:0048859 formation of anatomical boundary(GO:0048859)
0.0 0.3 GO:0009162 deoxyribonucleoside monophosphate metabolic process(GO:0009162)
0.0 0.4 GO:0031119 tRNA pseudouridine synthesis(GO:0031119)
0.0 0.6 GO:2000096 positive regulation of Wnt signaling pathway, planar cell polarity pathway(GO:2000096)
0.0 0.8 GO:0008340 determination of adult lifespan(GO:0008340)
0.0 0.6 GO:0046597 negative regulation of viral entry into host cell(GO:0046597)
0.0 0.3 GO:0035335 peptidyl-tyrosine dephosphorylation(GO:0035335)
0.0 0.2 GO:1990564 protein polyufmylation(GO:1990564) protein K69-linked ufmylation(GO:1990592)
0.0 0.2 GO:2000623 regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000622) negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000623)
0.0 0.1 GO:0097089 methyl-branched fatty acid metabolic process(GO:0097089)
0.0 1.6 GO:0045744 negative regulation of G-protein coupled receptor protein signaling pathway(GO:0045744)
0.0 0.1 GO:2000189 positive regulation of cholesterol homeostasis(GO:2000189)
0.0 0.3 GO:0098789 pre-mRNA cleavage required for polyadenylation(GO:0098789)
0.0 0.3 GO:0018230 peptidyl-L-cysteine S-palmitoylation(GO:0018230) peptidyl-S-diacylglycerol-L-cysteine biosynthetic process from peptidyl-cysteine(GO:0018231)
0.0 0.2 GO:0017196 N-terminal peptidyl-methionine acetylation(GO:0017196)
0.0 0.3 GO:0006488 dolichol-linked oligosaccharide biosynthetic process(GO:0006488)
0.0 1.5 GO:0002066 columnar/cuboidal epithelial cell development(GO:0002066)
0.0 0.9 GO:0006270 DNA replication initiation(GO:0006270)
0.0 0.4 GO:0021670 lateral ventricle development(GO:0021670)
0.0 0.0 GO:0051987 positive regulation of attachment of spindle microtubules to kinetochore(GO:0051987)
0.0 0.1 GO:0015744 succinate transport(GO:0015744)
0.0 0.1 GO:0098706 ferric iron import into cell(GO:0097461) ferric iron import across plasma membrane(GO:0098706)
0.0 0.4 GO:0051457 maintenance of protein location in nucleus(GO:0051457)
0.0 0.1 GO:0035720 intraciliary anterograde transport(GO:0035720)
0.0 0.2 GO:0030382 sperm mitochondrion organization(GO:0030382)
0.0 0.1 GO:0045654 positive regulation of megakaryocyte differentiation(GO:0045654)
0.0 0.8 GO:0032728 positive regulation of interferon-beta production(GO:0032728)
0.0 0.1 GO:0030210 heparin biosynthetic process(GO:0030210)
0.0 0.2 GO:1900262 regulation of DNA-directed DNA polymerase activity(GO:1900262) positive regulation of DNA-directed DNA polymerase activity(GO:1900264)
0.0 0.1 GO:0045743 positive regulation of fibroblast growth factor receptor signaling pathway(GO:0045743)
0.0 0.1 GO:0006741 NADP biosynthetic process(GO:0006741)
0.0 0.5 GO:0010866 regulation of triglyceride biosynthetic process(GO:0010866)
0.0 0.1 GO:2000569 T-helper 2 cell activation(GO:0035712) regulation of T-helper 2 cell activation(GO:2000569) positive regulation of T-helper 2 cell activation(GO:2000570)
0.0 0.2 GO:0045579 positive regulation of B cell differentiation(GO:0045579)
0.0 0.1 GO:0035902 response to immobilization stress(GO:0035902)
0.0 0.6 GO:0006303 double-strand break repair via nonhomologous end joining(GO:0006303)
0.0 0.2 GO:2000480 negative regulation of cAMP-dependent protein kinase activity(GO:2000480)
0.0 0.1 GO:0010739 positive regulation of protein kinase A signaling(GO:0010739)
0.0 0.1 GO:0032049 cardiolipin biosynthetic process(GO:0032049)
0.0 0.1 GO:0002339 B cell selection(GO:0002339)
0.0 0.0 GO:0010616 negative regulation of cardiac muscle adaptation(GO:0010616)
0.0 0.0 GO:1903061 regulation of protein lipidation(GO:1903059) positive regulation of protein lipidation(GO:1903061)
0.0 0.1 GO:0090043 regulation of tubulin deacetylation(GO:0090043)
0.0 0.1 GO:0051694 pointed-end actin filament capping(GO:0051694)
0.0 0.1 GO:1901668 regulation of superoxide dismutase activity(GO:1901668)
0.0 0.5 GO:1901998 toxin transport(GO:1901998)
0.0 0.2 GO:0006895 Golgi to endosome transport(GO:0006895)
0.0 0.9 GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)
0.0 0.1 GO:0016093 polyprenol metabolic process(GO:0016093)
0.0 0.2 GO:0006120 mitochondrial electron transport, NADH to ubiquinone(GO:0006120)
0.0 0.1 GO:0035520 monoubiquitinated protein deubiquitination(GO:0035520)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 3.0 GO:0000939 condensed chromosome inner kinetochore(GO:0000939)
0.4 1.1 GO:0071914 prominosome(GO:0071914)
0.3 0.3 GO:0005958 DNA-dependent protein kinase-DNA ligase 4 complex(GO:0005958)
0.3 0.8 GO:0097135 cyclin E2-CDK2 complex(GO:0097135)
0.2 0.6 GO:0042585 germinal vesicle(GO:0042585)
0.2 3.6 GO:0008074 guanylate cyclase complex, soluble(GO:0008074)
0.2 2.0 GO:0000940 condensed chromosome outer kinetochore(GO:0000940)
0.2 2.0 GO:0000164 protein phosphatase type 1 complex(GO:0000164)
0.2 0.5 GO:0005588 collagen type V trimer(GO:0005588)
0.1 8.5 GO:0005871 kinesin complex(GO:0005871)
0.1 2.3 GO:0035102 PRC1 complex(GO:0035102)
0.1 1.2 GO:1990907 beta-catenin-TCF complex(GO:1990907)
0.1 0.3 GO:0005943 phosphatidylinositol 3-kinase complex, class IA(GO:0005943)
0.1 0.4 GO:0070552 BRISC complex(GO:0070552)
0.1 0.6 GO:0032807 DNA ligase IV complex(GO:0032807)
0.1 0.7 GO:0032591 dendritic spine membrane(GO:0032591)
0.1 0.3 GO:0008622 epsilon DNA polymerase complex(GO:0008622)
0.1 0.9 GO:0036513 Derlin-1 retrotranslocation complex(GO:0036513)
0.1 0.8 GO:0034045 pre-autophagosomal structure membrane(GO:0034045)
0.1 0.3 GO:0034993 microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993)
0.0 3.5 GO:0030667 secretory granule membrane(GO:0030667)
0.0 1.2 GO:0051233 spindle midzone(GO:0051233)
0.0 0.5 GO:0043205 microfibril(GO:0001527) fibril(GO:0043205)
0.0 0.5 GO:0016589 NURF complex(GO:0016589)
0.0 2.4 GO:0016459 myosin complex(GO:0016459)
0.0 4.0 GO:0017053 transcriptional repressor complex(GO:0017053)
0.0 0.1 GO:0005947 mitochondrial alpha-ketoglutarate dehydrogenase complex(GO:0005947)
0.0 0.2 GO:0033116 endoplasmic reticulum-Golgi intermediate compartment membrane(GO:0033116)
0.0 0.7 GO:0033017 sarcoplasmic reticulum membrane(GO:0033017)
0.0 0.2 GO:0060293 P granule(GO:0043186) pole plasm(GO:0045495) germ plasm(GO:0060293)
0.0 1.2 GO:0097546 ciliary base(GO:0097546)
0.0 0.4 GO:0005922 connexon complex(GO:0005922)
0.0 0.2 GO:0005663 DNA replication factor C complex(GO:0005663)
0.0 0.3 GO:0005641 nuclear envelope lumen(GO:0005641)
0.0 0.3 GO:0005750 mitochondrial respiratory chain complex III(GO:0005750)
0.0 0.5 GO:0000800 lateral element(GO:0000800)
0.0 0.3 GO:0035253 ciliary rootlet(GO:0035253)
0.0 0.2 GO:0031415 NatA complex(GO:0031415)
0.0 0.7 GO:0032420 stereocilium(GO:0032420)
0.0 0.2 GO:0031595 nuclear proteasome complex(GO:0031595)
0.0 0.2 GO:0070822 Sin3-type complex(GO:0070822)
0.0 1.4 GO:0005902 microvillus(GO:0005902)
0.0 0.2 GO:0097197 tetraspanin-enriched microdomain(GO:0097197)
0.0 0.8 GO:0002102 podosome(GO:0002102)
0.0 0.1 GO:0001652 granular component(GO:0001652)
0.0 0.2 GO:0097227 sperm annulus(GO:0097227)
0.0 0.4 GO:0000242 pericentriolar material(GO:0000242)
0.0 0.4 GO:0030914 STAGA complex(GO:0030914)
0.0 0.2 GO:0000813 ESCRT I complex(GO:0000813)
0.0 2.2 GO:0090575 RNA polymerase II transcription factor complex(GO:0090575)
0.0 0.6 GO:0030673 axolemma(GO:0030673)
0.0 1.1 GO:0030864 cortical actin cytoskeleton(GO:0030864)
0.0 0.0 GO:0034272 phosphatidylinositol 3-kinase complex, class III, type I(GO:0034271) phosphatidylinositol 3-kinase complex, class III, type II(GO:0034272)
0.0 0.6 GO:0005788 endoplasmic reticulum lumen(GO:0005788)
0.0 1.6 GO:0031225 anchored component of membrane(GO:0031225)
0.0 0.2 GO:0032593 insulin-responsive compartment(GO:0032593)
0.0 0.6 GO:0008023 transcription elongation factor complex(GO:0008023)
0.0 0.2 GO:0032391 photoreceptor connecting cilium(GO:0032391)
0.0 0.1 GO:0008385 IkappaB kinase complex(GO:0008385)
0.0 0.1 GO:1990130 Iml1 complex(GO:1990130)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
1.2 3.6 GO:0016715 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced ascorbate as one donor, and incorporation of one atom of oxygen(GO:0016715)
1.1 3.2 GO:0042936 dipeptide transporter activity(GO:0042936)
0.4 1.2 GO:0008330 protein tyrosine/threonine phosphatase activity(GO:0008330)
0.3 1.7 GO:0000405 bubble DNA binding(GO:0000405)
0.3 2.0 GO:0071074 eukaryotic initiation factor eIF2 binding(GO:0071074)
0.3 1.8 GO:0030284 estrogen receptor activity(GO:0030284)
0.3 4.9 GO:0051010 microtubule plus-end binding(GO:0051010)
0.3 1.1 GO:0043515 kinetochore binding(GO:0043515)
0.2 0.7 GO:0030156 benzodiazepine receptor binding(GO:0030156)
0.2 1.0 GO:0004382 guanosine-diphosphatase activity(GO:0004382)
0.2 0.4 GO:0008732 threonine aldolase activity(GO:0004793) L-allo-threonine aldolase activity(GO:0008732)
0.2 3.6 GO:0004383 guanylate cyclase activity(GO:0004383)
0.2 0.5 GO:0070905 serine binding(GO:0070905)
0.2 1.2 GO:0070915 lysophosphatidic acid receptor activity(GO:0070915)
0.2 0.7 GO:0035800 deubiquitinase activator activity(GO:0035800)
0.1 0.6 GO:0015410 manganese-transporting ATPase activity(GO:0015410)
0.1 0.5 GO:0010484 H3 histone acetyltransferase activity(GO:0010484)
0.1 0.4 GO:0005118 sevenless binding(GO:0005118)
0.1 3.7 GO:0008574 ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574)
0.1 0.8 GO:0015616 DNA translocase activity(GO:0015616)
0.1 0.5 GO:0003681 bent DNA binding(GO:0003681)
0.1 0.6 GO:0004594 pantothenate kinase activity(GO:0004594)
0.1 0.4 GO:0015183 L-aspartate transmembrane transporter activity(GO:0015183)
0.1 0.3 GO:0008310 single-stranded DNA 3'-5' exodeoxyribonuclease activity(GO:0008310)
0.1 0.3 GO:0030171 voltage-gated proton channel activity(GO:0030171)
0.1 0.3 GO:0004145 diamine N-acetyltransferase activity(GO:0004145)
0.1 0.6 GO:0015501 glutamate:sodium symporter activity(GO:0015501)
0.1 0.5 GO:0004849 uridine kinase activity(GO:0004849)
0.1 0.3 GO:0016015 morphogen activity(GO:0016015)
0.1 0.3 GO:0004677 DNA-dependent protein kinase activity(GO:0004677)
0.1 0.6 GO:1901612 phosphatidylglycerol binding(GO:1901611) cardiolipin binding(GO:1901612)
0.1 0.3 GO:0003953 NAD+ nucleosidase activity(GO:0003953)
0.1 1.9 GO:0005521 lamin binding(GO:0005521)
0.1 0.2 GO:0030158 protein xylosyltransferase activity(GO:0030158)
0.1 0.4 GO:0070644 vitamin D response element binding(GO:0070644)
0.1 0.9 GO:0019855 calcium channel inhibitor activity(GO:0019855)
0.1 0.8 GO:0008430 selenium binding(GO:0008430)
0.1 0.5 GO:0016618 hydroxypyruvate reductase activity(GO:0016618) glyoxylate reductase (NADP) activity(GO:0030267)
0.1 1.5 GO:0001222 transcription corepressor binding(GO:0001222)
0.1 0.2 GO:0071568 UFM1 transferase activity(GO:0071568)
0.1 0.4 GO:0001758 retinal dehydrogenase activity(GO:0001758)
0.1 0.2 GO:0030549 acetylcholine receptor activator activity(GO:0030549)
0.1 2.6 GO:0031492 nucleosomal DNA binding(GO:0031492)
0.1 0.5 GO:0097200 cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:0097200)
0.1 0.2 GO:0004483 mRNA (nucleoside-2'-O-)-methyltransferase activity(GO:0004483)
0.1 0.3 GO:0001069 regulatory region RNA binding(GO:0001069)
0.0 0.7 GO:0003688 DNA replication origin binding(GO:0003688)
0.0 0.1 GO:0017153 sodium:dicarboxylate symporter activity(GO:0017153)
0.0 0.2 GO:0016841 ammonia-lyase activity(GO:0016841)
0.0 0.3 GO:0017040 ceramidase activity(GO:0017040)
0.0 0.7 GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
0.0 0.3 GO:0046934 phosphatidylinositol-4,5-bisphosphate 3-kinase activity(GO:0046934) phosphatidylinositol bisphosphate kinase activity(GO:0052813)
0.0 0.1 GO:0008823 cupric reductase activity(GO:0008823) ferric-chelate reductase (NADPH) activity(GO:0052851)
0.0 0.6 GO:0016805 dipeptidase activity(GO:0016805)
0.0 2.7 GO:0035064 methylated histone binding(GO:0035064)
0.0 0.3 GO:0048495 GTPase inhibitor activity(GO:0005095) Roundabout binding(GO:0048495)
0.0 0.1 GO:0004605 phosphatidate cytidylyltransferase activity(GO:0004605)
0.0 1.1 GO:0042805 actinin binding(GO:0042805)
0.0 0.1 GO:0034714 type III transforming growth factor beta receptor binding(GO:0034714)
0.0 0.2 GO:0003910 DNA ligase activity(GO:0003909) DNA ligase (ATP) activity(GO:0003910)
0.0 0.9 GO:0050136 NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.0 6.2 GO:0051015 actin filament binding(GO:0051015)
0.0 0.2 GO:0036402 proteasome-activating ATPase activity(GO:0036402)
0.0 0.5 GO:0005540 hyaluronic acid binding(GO:0005540)
0.0 0.6 GO:0004198 calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.0 0.2 GO:0070697 activin receptor binding(GO:0070697)
0.0 0.1 GO:0004035 alkaline phosphatase activity(GO:0004035)
0.0 1.0 GO:0005544 calcium-dependent phospholipid binding(GO:0005544)
0.0 0.8 GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity(GO:0016538)
0.0 4.2 GO:0001078 transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078)
0.0 0.4 GO:0009982 pseudouridine synthase activity(GO:0009982)
0.0 0.5 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.0 0.2 GO:0046790 virion binding(GO:0046790)
0.0 1.2 GO:0019003 GDP binding(GO:0019003)
0.0 0.2 GO:0043142 single-stranded DNA-dependent ATPase activity(GO:0043142)
0.0 0.3 GO:0031489 myosin V binding(GO:0031489)
0.0 0.1 GO:0004980 melanocortin receptor activity(GO:0004977) melanocyte-stimulating hormone receptor activity(GO:0004980)
0.0 2.8 GO:0004386 helicase activity(GO:0004386)
0.0 1.0 GO:0003707 steroid hormone receptor activity(GO:0003707)
0.0 0.1 GO:0052629 phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity(GO:0052629)
0.0 0.4 GO:0017056 structural constituent of nuclear pore(GO:0017056)
0.0 0.3 GO:0016799 hydrolase activity, hydrolyzing N-glycosyl compounds(GO:0016799)
0.0 0.3 GO:0102391 decanoate--CoA ligase activity(GO:0102391)
0.0 0.7 GO:0032266 phosphatidylinositol-3-phosphate binding(GO:0032266)
0.0 0.5 GO:0035035 histone acetyltransferase binding(GO:0035035)
0.0 0.3 GO:0008094 DNA-dependent ATPase activity(GO:0008094)
0.0 0.2 GO:0004862 cAMP-dependent protein kinase inhibitor activity(GO:0004862)
0.0 0.2 GO:0004596 peptide alpha-N-acetyltransferase activity(GO:0004596)
0.0 0.7 GO:0005179 hormone activity(GO:0005179)
0.0 0.2 GO:0004033 aldo-keto reductase (NADP) activity(GO:0004033)
0.0 0.1 GO:0005523 tropomyosin binding(GO:0005523)
0.0 0.2 GO:0017025 TBP-class protein binding(GO:0017025)
0.0 0.1 GO:0019871 sodium channel inhibitor activity(GO:0019871)
0.0 0.1 GO:0061578 Lys63-specific deubiquitinase activity(GO:0061578)
0.0 0.2 GO:0003746 translation elongation factor activity(GO:0003746)
0.0 0.0 GO:0004735 pyrroline-5-carboxylate reductase activity(GO:0004735)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 7.6 PID_AURORA_B_PATHWAY Aurora B signaling
0.1 3.5 PID_MYC_PATHWAY C-MYC pathway
0.1 4.2 PID_RET_PATHWAY Signaling events regulated by Ret tyrosine kinase
0.1 0.8 SA_REG_CASCADE_OF_CYCLIN_EXPR Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
0.0 1.3 ST_ERK1_ERK2_MAPK_PATHWAY ERK1/ERK2 MAPK Pathway
0.0 0.8 PID_DNA_PK_PATHWAY DNA-PK pathway in nonhomologous end joining
0.0 1.6 PID_CMYB_PATHWAY C-MYB transcription factor network
0.0 0.5 PID_DELTA_NP63_PATHWAY Validated transcriptional targets of deltaNp63 isoforms
0.0 0.5 PID_HIV_NEF_PATHWAY HIV-1 Nef: Negative effector of Fas and TNF-alpha
0.0 0.2 SA_TRKA_RECEPTOR The TrkA receptor binds nerve growth factor to activate MAP kinase pathways and promote cell growth.
0.0 0.1 PID_ERB_GENOMIC_PATHWAY Validated nuclear estrogen receptor beta network
0.0 0.5 PID_RETINOIC_ACID_PATHWAY Retinoic acid receptors-mediated signaling

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 7.0 REACTOME_KINESINS Genes involved in Kinesins
0.1 2.3 REACTOME_ACTIVATION_OF_RAC Genes involved in Activation of Rac
0.1 4.8 REACTOME_DEPOSITION_OF_NEW_CENPA_CONTAINING_NUCLEOSOMES_AT_THE_CENTROMERE Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere
0.1 1.2 REACTOME_ERKS_ARE_INACTIVATED Genes involved in ERKs are inactivated
0.1 0.6 REACTOME_REGULATION_OF_INSULIN_SECRETION_BY_ACETYLCHOLINE Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.1 3.6 REACTOME_AMINO_ACID_AND_OLIGOPEPTIDE_SLC_TRANSPORTERS Genes involved in Amino acid and oligopeptide SLC transporters
0.0 0.5 REACTOME_E2F_ENABLED_INHIBITION_OF_PRE_REPLICATION_COMPLEX_FORMATION Genes involved in E2F-enabled inhibition of pre-replication complex formation
0.0 0.6 REACTOME_VITAMIN_B5_PANTOTHENATE_METABOLISM Genes involved in Vitamin B5 (pantothenate) metabolism
0.0 0.5 REACTOME_HOMOLOGOUS_RECOMBINATION_REPAIR_OF_REPLICATION_INDEPENDENT_DOUBLE_STRAND_BREAKS Genes involved in Homologous recombination repair of replication-independent double-strand breaks
0.0 0.3 REACTOME_P2Y_RECEPTORS Genes involved in P2Y receptors
0.0 0.8 REACTOME_G0_AND_EARLY_G1 Genes involved in G0 and Early G1
0.0 0.5 REACTOME_REPAIR_SYNTHESIS_FOR_GAP_FILLING_BY_DNA_POL_IN_TC_NER Genes involved in Repair synthesis for gap-filling by DNA polymerase in TC-NER
0.0 0.7 REACTOME_TRAF6_MEDIATED_IRF7_ACTIVATION Genes involved in TRAF6 mediated IRF7 activation
0.0 1.4 REACTOME_NCAM1_INTERACTIONS Genes involved in NCAM1 interactions
0.0 0.3 REACTOME_DOUBLE_STRAND_BREAK_REPAIR Genes involved in Double-Strand Break Repair
0.0 0.8 REACTOME_INTERFERON_ALPHA_BETA_SIGNALING Genes involved in Interferon alpha/beta signaling
0.0 0.2 REACTOME_MEMBRANE_BINDING_AND_TARGETTING_OF_GAG_PROTEINS Genes involved in Membrane binding and targetting of GAG proteins
0.0 0.3 REACTOME_RECEPTOR_LIGAND_BINDING_INITIATES_THE_SECOND_PROTEOLYTIC_CLEAVAGE_OF_NOTCH_RECEPTOR Genes involved in Receptor-ligand binding initiates the second proteolytic cleavage of Notch receptor
0.0 0.6 REACTOME_ADHERENS_JUNCTIONS_INTERACTIONS Genes involved in Adherens junctions interactions
0.0 0.4 REACTOME_DOWNSTREAM_TCR_SIGNALING Genes involved in Downstream TCR signaling
0.0 0.5 REACTOME_NOD1_2_SIGNALING_PATHWAY Genes involved in NOD1/2 Signaling Pathway
0.0 0.3 REACTOME_SIGNALING_BY_NODAL Genes involved in Signaling by NODAL
0.0 0.2 REACTOME_NEGATIVE_REGULATION_OF_THE_PI3K_AKT_NETWORK Genes involved in Negative regulation of the PI3K/AKT network
0.0 0.3 REACTOME_CIRCADIAN_REPRESSION_OF_EXPRESSION_BY_REV_ERBA Genes involved in Circadian Repression of Expression by REV-ERBA
0.0 0.4 REACTOME_REGULATION_OF_GLUCOKINASE_BY_GLUCOKINASE_REGULATORY_PROTEIN Genes involved in Regulation of Glucokinase by Glucokinase Regulatory Protein
0.0 0.1 REACTOME_SYNTHESIS_OF_BILE_ACIDS_AND_BILE_SALTS_VIA_24_HYDROXYCHOLESTEROL Genes involved in Synthesis of bile acids and bile salts via 24-hydroxycholesterol
0.0 0.1 REACTOME_SPRY_REGULATION_OF_FGF_SIGNALING Genes involved in Spry regulation of FGF signaling
0.0 0.3 REACTOME_ENOS_ACTIVATION_AND_REGULATION Genes involved in eNOS activation and regulation
0.0 0.2 REACTOME_MYOGENESIS Genes involved in Myogenesis
0.0 0.2 REACTOME_NEF_MEDIATED_DOWNREGULATION_OF_MHC_CLASS_I_COMPLEX_CELL_SURFACE_EXPRESSION Genes involved in Nef mediated downregulation of MHC class I complex cell surface expression
0.0 0.1 REACTOME_BILE_SALT_AND_ORGANIC_ANION_SLC_TRANSPORTERS Genes involved in Bile salt and organic anion SLC transporters
0.0 0.2 REACTOME_AMINE_COMPOUND_SLC_TRANSPORTERS Genes involved in Amine compound SLC transporters