Motif ID: Foxm1

Z-value: 0.701


Transcription factors associated with Foxm1:

Gene SymbolEntrez IDGene Name
Foxm1 ENSMUSG00000001517.8 Foxm1

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Foxm1mm10_v2_chr6_+_128362919_128363058-0.048.0e-01Click!


Activity profile for motif Foxm1.

activity profile for motif Foxm1


Sorted Z-values histogram for motif Foxm1

Sorted Z-values for motif Foxm1



Network of associatons between targets according to the STRING database.



First level regulatory network of Foxm1

PNG image of the network

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Top targets:


Showing 1 to 20 of 150 entries
PromoterScoreRefseqGene SymbolGene Name
chr2_+_65845833 3.513 ENSMUST00000053910.3
 Csrnp3
cysteine-serine-rich nuclear protein 3
chr2_+_65845767 3.011 ENSMUST00000122912.1
 Csrnp3
cysteine-serine-rich nuclear protein 3
chr15_+_98167806 2.598 ENSMUST00000031914.4
 AI836003
expressed sequence AI836003
chr19_+_25672408 2.315 ENSMUST00000053068.5
 Dmrt2
doublesex and mab-3 related transcription factor 2
chrX_+_164373363 1.896 ENSMUST00000033751.7
 Figf
c-fos induced growth factor
chrX_-_141725181 1.881 ENSMUST00000067841.7
 Irs4
insulin receptor substrate 4
chr4_-_36136463 1.734 ENSMUST00000098151.2
 Lingo2
leucine rich repeat and Ig domain containing 2
chr8_+_58912257 1.714 ENSMUST00000160055.1
 BC030500
cDNA sequence BC030500
chr18_+_67133713 1.483 ENSMUST00000076605.7
 Gnal
guanine nucleotide binding protein, alpha stimulating, olfactory type
chr18_-_62741387 1.470 ENSMUST00000097557.3
 Spink13
serine peptidase inhibitor, Kazal type 13
chr1_-_79440039 1.467 ENSMUST00000049972.4
 Scg2
secretogranin II
chr1_-_138842429 1.456 ENSMUST00000112026.2
ENSMUST00000019374.7
 Lhx9

LIM homeobox protein 9

chr7_-_19921139 1.349 ENSMUST00000043517.7
 Pvr
poliovirus receptor
chr6_-_59024340 1.310 ENSMUST00000173193.1
 Fam13a
family with sequence similarity 13, member A
chr2_+_136052180 1.307 ENSMUST00000144403.1
 Lamp5
lysosomal-associated membrane protein family, member 5
chr3_+_134828993 1.255 ENSMUST00000029822.4
 Tacr3
tachykinin receptor 3
chr10_+_94576254 1.241 ENSMUST00000117929.1
 Tmcc3
transmembrane and coiled coil domains 3
chr12_-_40037387 1.212 ENSMUST00000146905.1
 Arl4a
ADP-ribosylation factor-like 4A
chr18_+_36952621 1.208 ENSMUST00000115661.2
 Pcdha2
protocadherin alpha 2
chr8_+_34807287 1.147 ENSMUST00000033930.4
 Dusp4
dual specificity phosphatase 4

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 60 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 6.5 GO:0010923 negative regulation of phosphatase activity(GO:0010923)
0.6 2.3 GO:0061055 myotome development(GO:0061055)
0.0 2.1 GO:0050731 positive regulation of peptidyl-tyrosine phosphorylation(GO:0050731)
0.0 1.7 GO:0051965 positive regulation of synapse assembly(GO:0051965)
0.3 1.5 GO:0060467 negative regulation of fertilization(GO:0060467)
0.3 1.5 GO:0048245 eosinophil chemotaxis(GO:0048245)
0.3 1.5 GO:0035262 gonad morphogenesis(GO:0035262)
0.2 1.5 GO:0009405 pathogenesis(GO:0009405)
0.4 1.3 GO:0002423 natural killer cell mediated cytotoxicity directed against tumor cell target(GO:0002420) natural killer cell mediated immune response to tumor cell(GO:0002423) regulation of natural killer cell mediated immune response to tumor cell(GO:0002855) regulation of natural killer cell mediated cytotoxicity directed against tumor cell target(GO:0002858) susceptibility to natural killer cell mediated cytotoxicity(GO:0042271)
0.2 1.3 GO:0070474 positive regulation of uterine smooth muscle contraction(GO:0070474)
0.0 1.3 GO:0008286 insulin receptor signaling pathway(GO:0008286)
0.1 1.2 GO:1900383 regulation of synaptic plasticity by receptor localization to synapse(GO:1900383)
0.0 1.2 GO:0050873 brown fat cell differentiation(GO:0050873)
0.1 1.1 GO:0035970 peptidyl-threonine dephosphorylation(GO:0035970)
0.1 1.0 GO:0071420 cellular response to histamine(GO:0071420)
0.1 1.0 GO:0019886 antigen processing and presentation of exogenous peptide antigen via MHC class II(GO:0019886)
0.1 0.8 GO:0051694 pointed-end actin filament capping(GO:0051694)
0.1 0.8 GO:0000733 DNA strand renaturation(GO:0000733)
0.1 0.8 GO:0048386 positive regulation of retinoic acid receptor signaling pathway(GO:0048386)
0.1 0.8 GO:1900119 positive regulation of execution phase of apoptosis(GO:1900119)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 32 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 2.5 GO:0031225 anchored component of membrane(GO:0031225)
0.0 1.9 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.1 1.5 GO:0031045 dense core granule(GO:0031045)
0.0 1.5 GO:0001669 acrosomal vesicle(GO:0001669)
0.2 1.3 GO:0033116 endoplasmic reticulum-Golgi intermediate compartment membrane(GO:0033116)
0.0 1.3 GO:0005913 cell-cell adherens junction(GO:0005913)
0.0 1.3 GO:0032590 dendrite membrane(GO:0032590)
0.1 1.0 GO:0042613 MHC class II protein complex(GO:0042613)
0.1 1.0 GO:1902711 GABA-A receptor complex(GO:1902711)
0.0 0.8 GO:0097470 ribbon synapse(GO:0097470)
0.0 0.8 GO:0005865 striated muscle thin filament(GO:0005865) myofilament(GO:0036379)
0.0 0.6 GO:0016471 vacuolar proton-transporting V-type ATPase complex(GO:0016471)
0.0 0.5 GO:0097136 Bcl-2 family protein complex(GO:0097136)
0.0 0.5 GO:0034451 centriolar satellite(GO:0034451)
0.1 0.4 GO:0001652 granular component(GO:0001652)
0.0 0.4 GO:0071541 eukaryotic translation initiation factor 3 complex, eIF3m(GO:0071541)
0.0 0.4 GO:0072546 ER membrane protein complex(GO:0072546)
0.0 0.4 GO:0033655 host cell cytoplasm(GO:0030430) host cell cytoplasm part(GO:0033655)
0.0 0.4 GO:0031932 TORC2 complex(GO:0031932)
0.0 0.4 GO:0000795 synaptonemal complex(GO:0000795)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 47 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 7.0 GO:0001228 transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001228)
0.0 1.9 GO:0043548 phosphatidylinositol 3-kinase binding(GO:0043548)
0.1 1.5 GO:0042056 chemoattractant activity(GO:0042056)
0.1 1.5 GO:0031683 G-protein beta/gamma-subunit complex binding(GO:0031683)
0.0 1.5 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.0 1.4 GO:0005178 integrin binding(GO:0005178)
0.1 1.3 GO:0001618 virus receptor activity(GO:0001618)
0.1 1.3 GO:0008188 neuropeptide receptor activity(GO:0008188)
0.0 1.2 GO:0046875 ephrin receptor binding(GO:0046875)
0.4 1.1 GO:0008330 protein tyrosine/threonine phosphatase activity(GO:0008330)
0.1 1.0 GO:0004890 GABA-A receptor activity(GO:0004890)
0.1 0.8 GO:0009378 four-way junction helicase activity(GO:0009378)
0.1 0.8 GO:0016618 hydroxypyruvate reductase activity(GO:0016618) glyoxylate reductase (NADP) activity(GO:0030267)
0.1 0.8 GO:0005523 tropomyosin binding(GO:0005523)
0.0 0.8 GO:0043274 phospholipase binding(GO:0043274)
0.1 0.7 GO:0008395 steroid hydroxylase activity(GO:0008395)
0.1 0.6 GO:0008553 hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553)
0.0 0.6 GO:0102391 decanoate--CoA ligase activity(GO:0102391)
0.1 0.5 GO:0051434 BH3 domain binding(GO:0051434)
0.1 0.4 GO:0008988 rRNA (adenine-N6-)-methyltransferase activity(GO:0008988) U6 snRNA 3'-end binding(GO:0030629)

Gene overrepresentation in C2:CP category:

Showing 1 to 9 of 9 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 2.3 SIG_PIP3_SIGNALING_IN_CARDIAC_MYOCTES Genes related to PIP3 signaling in cardiac myocytes
0.0 2.1 PID_RET_PATHWAY Signaling events regulated by Ret tyrosine kinase
0.2 1.9 PID_VEGF_VEGFR_PATHWAY VEGF and VEGFR signaling network
0.1 1.5 PID_LPA4_PATHWAY LPA4-mediated signaling events
0.0 1.5 ST_JNK_MAPK_PATHWAY JNK MAPK Pathway
0.0 1.3 PID_NECTIN_PATHWAY Nectin adhesion pathway
0.0 0.8 PID_RHOA_REG_PATHWAY Regulation of RhoA activity
0.0 0.4 PID_RHODOPSIN_PATHWAY Visual signal transduction: Rods
0.0 0.4 PID_TCPTP_PATHWAY Signaling events mediated by TCPTP

Gene overrepresentation in C2:CP:REACTOME category:

Showing 1 to 19 of 19 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 2.1 REACTOME_NCAM1_INTERACTIONS Genes involved in NCAM1 interactions
0.0 2.1 REACTOME_SIGNALING_BY_RHO_GTPASES Genes involved in Signaling by Rho GTPases
0.4 1.9 REACTOME_OLFACTORY_SIGNALING_PATHWAY Genes involved in Olfactory Signaling Pathway
0.2 1.9 REACTOME_VEGF_LIGAND_RECEPTOR_INTERACTIONS Genes involved in VEGF ligand-receptor interactions
0.1 1.3 REACTOME_IMMUNOREGULATORY_INTERACTIONS_BETWEEN_A_LYMPHOID_AND_A_NON_LYMPHOID_CELL Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
0.1 1.1 REACTOME_ERKS_ARE_INACTIVATED Genes involved in ERKs are inactivated
0.1 1.0 REACTOME_GABA_A_RECEPTOR_ACTIVATION Genes involved in GABA A receptor activation
0.0 1.0 REACTOME_PEPTIDE_LIGAND_BINDING_RECEPTORS Genes involved in Peptide ligand-binding receptors
0.1 0.7 REACTOME_ENDOGENOUS_STEROLS Genes involved in Endogenous sterols
0.1 0.6 REACTOME_GLUCURONIDATION Genes involved in Glucuronidation
0.0 0.6 REACTOME_INSULIN_RECEPTOR_RECYCLING Genes involved in Insulin receptor recycling
0.0 0.6 REACTOME_SYNTHESIS_OF_VERY_LONG_CHAIN_FATTY_ACYL_COAS Genes involved in Synthesis of very long-chain fatty acyl-CoAs
0.0 0.5 REACTOME_INFLAMMASOMES Genes involved in Inflammasomes
0.0 0.4 REACTOME_BASE_FREE_SUGAR_PHOSPHATE_REMOVAL_VIA_THE_SINGLE_NUCLEOTIDE_REPLACEMENT_PATHWAY Genes involved in Base-free sugar-phosphate removal via the single-nucleotide replacement pathway
0.0 0.4 REACTOME_ACTIVATION_OF_THE_AP1_FAMILY_OF_TRANSCRIPTION_FACTORS Genes involved in Activation of the AP-1 family of transcription factors
0.0 0.3 REACTOME_PASSIVE_TRANSPORT_BY_AQUAPORINS Genes involved in Passive Transport by Aquaporins
0.0 0.3 REACTOME_RNA_POL_III_CHAIN_ELONGATION Genes involved in RNA Polymerase III Chain Elongation
0.0 0.3 REACTOME_FORMATION_OF_ATP_BY_CHEMIOSMOTIC_COUPLING Genes involved in Formation of ATP by chemiosmotic coupling
0.0 0.2 REACTOME_SYNTHESIS_SECRETION_AND_INACTIVATION_OF_GIP Genes involved in Synthesis, Secretion, and Inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)