Motif ID: Foxm1

Z-value: 0.701


Transcription factors associated with Foxm1:

Gene SymbolEntrez IDGene Name
Foxm1 ENSMUSG00000001517.8 Foxm1

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Foxm1mm10_v2_chr6_+_128362919_128363058-0.048.0e-01Click!


Activity profile for motif Foxm1.

activity profile for motif Foxm1


Sorted Z-values histogram for motif Foxm1

Sorted Z-values for motif Foxm1



Network of associatons between targets according to the STRING database.



First level regulatory network of Foxm1

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr2_+_65845833 3.513 ENSMUST00000053910.3
Csrnp3
cysteine-serine-rich nuclear protein 3
chr2_+_65845767 3.011 ENSMUST00000122912.1
Csrnp3
cysteine-serine-rich nuclear protein 3
chr15_+_98167806 2.598 ENSMUST00000031914.4
AI836003
expressed sequence AI836003
chr19_+_25672408 2.315 ENSMUST00000053068.5
Dmrt2
doublesex and mab-3 related transcription factor 2
chrX_+_164373363 1.896 ENSMUST00000033751.7
Figf
c-fos induced growth factor
chrX_-_141725181 1.881 ENSMUST00000067841.7
Irs4
insulin receptor substrate 4
chr4_-_36136463 1.734 ENSMUST00000098151.2
Lingo2
leucine rich repeat and Ig domain containing 2
chr8_+_58912257 1.714 ENSMUST00000160055.1
BC030500
cDNA sequence BC030500
chr18_+_67133713 1.483 ENSMUST00000076605.7
Gnal
guanine nucleotide binding protein, alpha stimulating, olfactory type
chr18_-_62741387 1.470 ENSMUST00000097557.3
Spink13
serine peptidase inhibitor, Kazal type 13
chr1_-_79440039 1.467 ENSMUST00000049972.4
Scg2
secretogranin II
chr1_-_138842429 1.456 ENSMUST00000112026.2
ENSMUST00000019374.7
Lhx9

LIM homeobox protein 9

chr7_-_19921139 1.349 ENSMUST00000043517.7
Pvr
poliovirus receptor
chr6_-_59024340 1.310 ENSMUST00000173193.1
Fam13a
family with sequence similarity 13, member A
chr2_+_136052180 1.307 ENSMUST00000144403.1
Lamp5
lysosomal-associated membrane protein family, member 5
chr3_+_134828993 1.255 ENSMUST00000029822.4
Tacr3
tachykinin receptor 3
chr10_+_94576254 1.241 ENSMUST00000117929.1
Tmcc3
transmembrane and coiled coil domains 3
chr12_-_40037387 1.212 ENSMUST00000146905.1
Arl4a
ADP-ribosylation factor-like 4A
chr18_+_36952621 1.208 ENSMUST00000115661.2
Pcdha2
protocadherin alpha 2
chr8_+_34807287 1.147 ENSMUST00000033930.4
Dusp4
dual specificity phosphatase 4
chr9_-_100571049 1.033 ENSMUST00000093792.2
Slc35g2
solute carrier family 35, member G2
chr17_+_34305883 0.966 ENSMUST00000074557.8
H2-Eb1
histocompatibility 2, class II antigen E beta
chr6_+_142413441 0.951 ENSMUST00000088263.4
B230216G23Rik
RIKEN cDNA B230216G23 gene
chr14_-_5455467 0.950 ENSMUST00000180867.1
Gm3194
predicted gene 3194
chr6_+_142413833 0.909 ENSMUST00000126521.2
B230216G23Rik
RIKEN cDNA B230216G23 gene
chr6_+_142414012 0.873 ENSMUST00000141548.1
B230216G23Rik
RIKEN cDNA B230216G23 gene
chr8_-_36732897 0.825 ENSMUST00000098826.3
Dlc1
deleted in liver cancer 1
chr9_-_75597643 0.799 ENSMUST00000164100.1
Tmod2
tropomodulin 2
chr19_-_58455161 0.790 ENSMUST00000135730.1
ENSMUST00000152507.1
Gfra1

glial cell line derived neurotrophic factor family receptor alpha 1

chr10_+_112928501 0.751 ENSMUST00000180464.1
Gm26596
predicted gene, 26596
chr10_-_63927434 0.735 ENSMUST00000079279.3
Gm10118
predicted gene 10118
chr19_-_58455903 0.731 ENSMUST00000131877.1
Gfra1
glial cell line derived neurotrophic factor family receptor alpha 1
chr5_-_125390176 0.702 ENSMUST00000156249.1
Ubc
ubiquitin C
chr1_+_74713551 0.654 ENSMUST00000027356.5
Cyp27a1
cytochrome P450, family 27, subfamily a, polypeptide 1
chr10_+_90829780 0.651 ENSMUST00000179337.2
Anks1b
ankyrin repeat and sterile alpha motif domain containing 1B
chr6_+_142387215 0.641 ENSMUST00000032372.6
Golt1b
golgi transport 1 homolog B (S. cerevisiae)
chr4_+_63544747 0.618 ENSMUST00000035301.6
Atp6v1g1
ATPase, H+ transporting, lysosomal V1 subunit G1
chr2_+_138278481 0.617 ENSMUST00000075410.4
Btbd3
BTB (POZ) domain containing 3
chr11_-_3266377 0.617 ENSMUST00000020741.5
Drg1
developmentally regulated GTP binding protein 1
chr19_+_55253369 0.615 ENSMUST00000043150.4
Acsl5
acyl-CoA synthetase long-chain family member 5
chr19_-_58455398 0.602 ENSMUST00000026076.7
Gfra1
glial cell line derived neurotrophic factor family receptor alpha 1
chr10_+_90829835 0.598 ENSMUST00000179964.1
Anks1b
ankyrin repeat and sterile alpha motif domain containing 1B
chr7_+_83755904 0.592 ENSMUST00000051522.8
ENSMUST00000042280.7
Gm7964

predicted gene 7964

chr5_-_24581879 0.581 ENSMUST00000088299.4
Gm10221
predicted gene 10221
chr4_-_15149755 0.573 ENSMUST00000108273.1
Necab1
N-terminal EF-hand calcium binding protein 1
chr11_-_42000284 0.551 ENSMUST00000109292.2
ENSMUST00000109290.1
Gabrg2

gamma-aminobutyric acid (GABA) A receptor, subunit gamma 2

chr7_-_30072801 0.550 ENSMUST00000183115.1
ENSMUST00000182919.1
ENSMUST00000183190.1
ENSMUST00000080834.8
Zfp82



zinc finger protein 82



chr5_+_137553517 0.549 ENSMUST00000136088.1
ENSMUST00000139395.1
ENSMUST00000136565.1
ENSMUST00000149292.1
ENSMUST00000125489.1
Actl6b




actin-like 6B




chr7_+_31059342 0.535 ENSMUST00000039775.7
Lgi4
leucine-rich repeat LGI family, member 4
chr9_-_121839460 0.496 ENSMUST00000135986.2
Ccdc13
coiled-coil domain containing 13
chr2_-_152831665 0.463 ENSMUST00000156688.1
ENSMUST00000007803.5
Bcl2l1

BCL2-like 1

chr7_-_126566364 0.450 ENSMUST00000032992.5
Eif3c
eukaryotic translation initiation factor 3, subunit C
chr2_-_32424005 0.439 ENSMUST00000113307.2
Slc25a25
solute carrier family 25 (mitochondrial carrier, phosphate carrier), member 25
chrX_+_9885622 0.439 ENSMUST00000067529.2
ENSMUST00000086165.3
Sytl5

synaptotagmin-like 5

chr11_-_42000532 0.439 ENSMUST00000070735.3
Gabrg2
gamma-aminobutyric acid (GABA) A receptor, subunit gamma 2
chr16_-_46155077 0.434 ENSMUST00000059524.5
Gm4737
predicted gene 4737
chr7_-_133123770 0.431 ENSMUST00000164896.1
ENSMUST00000171968.1
Ctbp2

C-terminal binding protein 2

chr4_+_155522462 0.430 ENSMUST00000177094.1
Gnb1
guanine nucleotide binding protein (G protein), beta 1
chr2_-_165852149 0.428 ENSMUST00000109258.3
Zmynd8
zinc finger, MYND-type containing 8
chr6_-_142386974 0.422 ENSMUST00000129694.1
Recql
RecQ protein-like
chr10_-_20725023 0.419 ENSMUST00000020165.7
Pde7b
phosphodiesterase 7B
chr18_-_66022580 0.410 ENSMUST00000143990.1
Lman1
lectin, mannose-binding, 1
chr4_-_44710408 0.408 ENSMUST00000134968.2
ENSMUST00000173821.1
ENSMUST00000174319.1
ENSMUST00000173733.1
ENSMUST00000172866.1
ENSMUST00000165417.2
ENSMUST00000107825.2
ENSMUST00000102932.3
ENSMUST00000107827.2
ENSMUST00000107826.2
Pax5









paired box gene 5









chr10_+_11281583 0.407 ENSMUST00000070300.4
Fbxo30
F-box protein 30
chr11_+_74770822 0.406 ENSMUST00000141755.1
ENSMUST00000010698.6
Mettl16

methyltransferase like 16

chr8_-_22653406 0.404 ENSMUST00000033938.5
Polb
polymerase (DNA directed), beta
chr13_+_43370710 0.403 ENSMUST00000066804.4
Sirt5
sirtuin 5
chr4_-_141790891 0.400 ENSMUST00000038014.4
ENSMUST00000153880.1
Dnajc16

DnaJ (Hsp40) homolog, subfamily C, member 16

chr6_-_13871477 0.391 ENSMUST00000139231.1
2610001J05Rik
RIKEN cDNA 2610001J05 gene
chr12_-_51971289 0.391 ENSMUST00000040583.5
Heatr5a
HEAT repeat containing 5A
chr6_-_13871459 0.388 ENSMUST00000155856.1
2610001J05Rik
RIKEN cDNA 2610001J05 gene
chr4_-_103215147 0.386 ENSMUST00000150285.1
Slc35d1
solute carrier family 35 (UDP-glucuronic acid/UDP-N-acetylgalactosamine dual transporter), member D1
chr18_-_20682963 0.381 ENSMUST00000165229.2
Gm10269
predicted gene 10269
chr3_+_106113229 0.376 ENSMUST00000079132.5
ENSMUST00000139086.1
Chia

chitinase, acidic

chr5_-_103211251 0.375 ENSMUST00000060871.5
ENSMUST00000112846.1
ENSMUST00000170792.1
ENSMUST00000112847.2
Mapk10



mitogen-activated protein kinase 10



chr6_-_142387035 0.368 ENSMUST00000032370.6
ENSMUST00000100832.3
ENSMUST00000128082.1
ENSMUST00000111803.2
Recql



RecQ protein-like



chr11_-_78183551 0.367 ENSMUST00000102483.4
Rpl23a
ribosomal protein L23A
chrX_-_56598069 0.362 ENSMUST00000059899.2
Mmgt1
membrane magnesium transporter 1
chr8_-_47713920 0.354 ENSMUST00000038738.5
Cdkn2aip
CDKN2A interacting protein
chr2_+_104095796 0.348 ENSMUST00000040423.5
ENSMUST00000168176.1
Cd59a

CD59a antigen

chr13_+_55209776 0.344 ENSMUST00000099490.2
Nsd1
nuclear receptor-binding SET-domain protein 1
chr11_-_34833631 0.339 ENSMUST00000093191.2
Spdl1
spindle apparatus coiled-coil protein 1
chr16_+_17208135 0.338 ENSMUST00000169803.1
Rimbp3
RIMS binding protein 3
chr7_-_133123409 0.334 ENSMUST00000170459.1
ENSMUST00000166400.1
Ctbp2

C-terminal binding protein 2

chr12_-_99393010 0.324 ENSMUST00000177451.1
Foxn3
forkhead box N3
chr2_+_10372426 0.314 ENSMUST00000114864.2
ENSMUST00000116594.2
ENSMUST00000041105.6
Sfmbt2


Scm-like with four mbt domains 2


chr10_+_11281304 0.312 ENSMUST00000129456.1
Fbxo30
F-box protein 30
chr1_+_89454769 0.311 ENSMUST00000027521.8
ENSMUST00000074945.5
Agap1

ArfGAP with GTPase domain, ankyrin repeat and PH domain 1

chr6_-_148944750 0.306 ENSMUST00000111562.1
ENSMUST00000081956.5
Fam60a

family with sequence similarity 60, member A

chr10_+_127849917 0.305 ENSMUST00000077530.2
Rdh19
retinol dehydrogenase 19
chr2_+_68117713 0.297 ENSMUST00000112346.2
B3galt1
UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 1
chr13_-_23934156 0.292 ENSMUST00000052776.2
Hist1h2ba
histone cluster 1, H2ba
chr9_-_71163224 0.285 ENSMUST00000074465.2
Aqp9
aquaporin 9
chr11_-_96075581 0.279 ENSMUST00000107686.1
ENSMUST00000107684.1
Atp5g1

ATP synthase, H+ transporting, mitochondrial F0 complex, subunit c1 (subunit 9)

chrX_-_75578188 0.272 ENSMUST00000033545.5
Rab39b
RAB39B, member RAS oncogene family
chr13_+_23934434 0.263 ENSMUST00000072391.1
Hist1h2aa
histone cluster 1, H2aa
chr5_-_87490869 0.257 ENSMUST00000147854.1
Ugt2a1
UDP glucuronosyltransferase 2 family, polypeptide A1
chr8_-_41417042 0.256 ENSMUST00000033999.6
Frg1
FSHD region gene 1
chr15_+_36174010 0.244 ENSMUST00000180159.1
ENSMUST00000057177.6
Polr2k

polymerase (RNA) II (DNA directed) polypeptide K

chr10_-_88605017 0.242 ENSMUST00000119185.1
ENSMUST00000121629.1
Mybpc1

myosin binding protein C, slow-type

chr12_-_80760541 0.239 ENSMUST00000073251.6
Ccdc177
coiled-coil domain containing 177
chr4_-_143299498 0.236 ENSMUST00000030317.7
Pdpn
podoplanin
chr3_-_28765364 0.233 ENSMUST00000094335.3
Gm6505
predicted pseudogene 6505
chr13_-_92483996 0.233 ENSMUST00000040106.7
Fam151b
family with sequence similarity 151, member B
chr7_-_30626145 0.218 ENSMUST00000075738.4
Cox6b1
cytochrome c oxidase, subunit VIb polypeptide 1
chr5_-_140321524 0.214 ENSMUST00000031534.6
Mad1l1
MAD1 mitotic arrest deficient 1-like 1
chr3_-_106167564 0.204 ENSMUST00000063062.8
Chi3l3
chitinase 3-like 3
chr3_+_76075583 0.202 ENSMUST00000160261.1
Fstl5
follistatin-like 5
chr10_-_81230773 0.202 ENSMUST00000047408.4
Atcay
ataxia, cerebellar, Cayman type homolog (human)
chr11_-_97996171 0.201 ENSMUST00000042971.9
Arl5c
ADP-ribosylation factor-like 5C
chr7_-_28949670 0.194 ENSMUST00000148196.1
Actn4
actinin alpha 4
chrX_+_112311334 0.186 ENSMUST00000026599.3
ENSMUST00000113415.1
Apool

apolipoprotein O-like

chr8_-_54529951 0.178 ENSMUST00000067476.8
Spcs3
signal peptidase complex subunit 3 homolog (S. cerevisiae)
chr9_+_3532295 0.176 ENSMUST00000115733.1
Gucy1a2
guanylate cyclase 1, soluble, alpha 2
chr2_+_96318014 0.162 ENSMUST00000135431.1
ENSMUST00000162807.2
Lrrc4c

leucine rich repeat containing 4C

chr3_-_95357156 0.152 ENSMUST00000107171.3
ENSMUST00000015841.5
ENSMUST00000107170.2
Setdb1


SET domain, bifurcated 1


chr6_-_71823805 0.139 ENSMUST00000065103.2
Mrpl35
mitochondrial ribosomal protein L35
chr7_+_19382005 0.134 ENSMUST00000062831.9
ENSMUST00000108461.1
ENSMUST00000108460.1
Ercc2


excision repair cross-complementing rodent repair deficiency, complementation group 2


chr1_-_75142360 0.121 ENSMUST00000041213.5
Cnppd1
cyclin Pas1/PHO80 domain containing 1
chr1_+_171331414 0.119 ENSMUST00000097467.1
Dedd
death effector domain-containing
chr5_+_145140362 0.118 ENSMUST00000162594.1
ENSMUST00000162308.1
ENSMUST00000159018.1
ENSMUST00000160075.1
Bud31



BUD31 homolog (yeast)



chr12_+_98628126 0.116 ENSMUST00000048402.5
ENSMUST00000101144.3
ENSMUST00000101146.3
Spata7


spermatogenesis associated 7


chrX_+_38600626 0.115 ENSMUST00000000365.2
Mcts1
malignant T cell amplified sequence 1
chr18_-_65939048 0.111 ENSMUST00000025396.3
Rax
retina and anterior neural fold homeobox
chr10_-_13193096 0.109 ENSMUST00000019950.4
Ltv1
LTV1 homolog (S. cerevisiae)
chr7_-_103741322 0.107 ENSMUST00000051346.2
Olfr629
olfactory receptor 629
chr14_-_24486994 0.092 ENSMUST00000026322.7
Polr3a
polymerase (RNA) III (DNA directed) polypeptide A
chr2_-_30048827 0.090 ENSMUST00000113711.2
Wdr34
WD repeat domain 34
chr14_-_41008256 0.085 ENSMUST00000136661.1
Fam213a
family with sequence similarity 213, member A
chr19_-_7019423 0.079 ENSMUST00000040772.8
Fermt3
fermitin family homolog 3 (Drosophila)
chr14_+_73173825 0.076 ENSMUST00000166875.1
Rcbtb2
regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 2
chr5_+_31526989 0.072 ENSMUST00000114533.2
ENSMUST00000117262.1
ENSMUST00000117319.1
Slc4a1ap


solute carrier family 4 (anion exchanger), member 1, adaptor protein


chr1_+_75142775 0.066 ENSMUST00000097694.4
Fam134a
family with sequence similarity 134, member A
chrM_+_5319 0.063 ENSMUST00000082402.1
mt-Co1
mitochondrially encoded cytochrome c oxidase I
chr15_+_102460076 0.053 ENSMUST00000164688.1
Prr13
proline rich 13
chr2_+_131210363 0.051 ENSMUST00000110210.1
ENSMUST00000089506.5
ENSMUST00000110208.1
Ap5s1


adaptor-related protein 5 complex, sigma 1 subunit


chr2_+_167015193 0.051 ENSMUST00000018143.9
ENSMUST00000176066.1
ENSMUST00000150571.1
Ddx27


DEAD (Asp-Glu-Ala-Asp) box polypeptide 27


chr16_-_35490873 0.048 ENSMUST00000023550.7
Pdia5
protein disulfide isomerase associated 5
chr10_+_127421124 0.046 ENSMUST00000170336.1
R3hdm2
R3H domain containing 2
chr2_+_107290590 0.037 ENSMUST00000037012.2
Kcna4
potassium voltage-gated channel, shaker-related subfamily, member 4
chr4_-_117891994 0.035 ENSMUST00000030265.3
Dph2
DPH2 homolog (S. cerevisiae)
chr11_-_110168073 0.032 ENSMUST00000044850.3
Abca9
ATP-binding cassette, sub-family A (ABC1), member 9
chr7_-_80901220 0.029 ENSMUST00000146402.1
ENSMUST00000026816.8
Wdr73

WD repeat domain 73

chr6_-_122340525 0.021 ENSMUST00000112600.2
Phc1
polyhomeotic-like 1 (Drosophila)
chr12_+_3365108 0.018 ENSMUST00000020999.5
Kif3c
kinesin family member 3C
chr4_-_120951664 0.017 ENSMUST00000106280.1
Zfp69
zinc finger protein 69
chr4_+_143413002 0.015 ENSMUST00000155157.1
Pramef8
PRAME family member 8
chr4_+_33209259 0.012 ENSMUST00000108159.1
Srsf12
serine/arginine-rich splicing factor 12
chr17_-_86145139 0.009 ENSMUST00000095187.3
Srbd1
S1 RNA binding domain 1
chr17_+_6079928 0.000 ENSMUST00000100955.2
Gtf2h5
general transcription factor IIH, polypeptide 5

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 2.3 GO:0061055 myotome development(GO:0061055)
0.4 1.3 GO:0002423 natural killer cell mediated cytotoxicity directed against tumor cell target(GO:0002420) natural killer cell mediated immune response to tumor cell(GO:0002423) regulation of natural killer cell mediated immune response to tumor cell(GO:0002855) regulation of natural killer cell mediated cytotoxicity directed against tumor cell target(GO:0002858) susceptibility to natural killer cell mediated cytotoxicity(GO:0042271)
0.3 1.5 GO:0060467 negative regulation of fertilization(GO:0060467)
0.3 1.5 GO:0048245 eosinophil chemotaxis(GO:0048245)
0.3 1.5 GO:0035262 gonad morphogenesis(GO:0035262)
0.2 1.5 GO:0009405 pathogenesis(GO:0009405)
0.2 1.3 GO:0070474 positive regulation of uterine smooth muscle contraction(GO:0070474)
0.1 0.4 GO:0071707 immunoglobulin heavy chain V-D-J recombination(GO:0071707)
0.1 0.8 GO:0051694 pointed-end actin filament capping(GO:0051694)
0.1 0.8 GO:0000733 DNA strand renaturation(GO:0000733)
0.1 0.5 GO:0046898 response to cycloheximide(GO:0046898)
0.1 1.0 GO:0071420 cellular response to histamine(GO:0071420)
0.1 1.2 GO:1900383 regulation of synaptic plasticity by receptor localization to synapse(GO:1900383)
0.1 0.6 GO:0010747 positive regulation of plasma membrane long-chain fatty acid transport(GO:0010747)
0.1 0.4 GO:0007603 phototransduction, visible light(GO:0007603)
0.1 0.4 GO:1903756 regulation of transcription from RNA polymerase II promoter by histone modification(GO:1903756) negative regulation of transcription from RNA polymerase II promoter by histone modification(GO:1903758)
0.1 6.5 GO:0010923 negative regulation of phosphatase activity(GO:0010923)
0.1 1.0 GO:0019886 antigen processing and presentation of exogenous peptide antigen via MHC class II(GO:0019886)
0.1 0.8 GO:0048386 positive regulation of retinoic acid receptor signaling pathway(GO:0048386)
0.1 1.1 GO:0035970 peptidyl-threonine dephosphorylation(GO:0035970)
0.1 0.2 GO:0045763 negative regulation of cellular amino acid metabolic process(GO:0045763)
0.1 0.2 GO:1902396 protein localization to bicellular tight junction(GO:1902396)
0.1 0.4 GO:0007258 JUN phosphorylation(GO:0007258)
0.1 0.2 GO:0071688 striated muscle myosin thick filament assembly(GO:0071688)
0.1 0.8 GO:1900119 positive regulation of execution phase of apoptosis(GO:1900119)
0.1 0.3 GO:0090272 negative regulation of fibroblast growth factor production(GO:0090272)
0.1 0.2 GO:0090235 regulation of metaphase plate congression(GO:0090235)
0.1 0.3 GO:0052695 cellular glucuronidation(GO:0052695)
0.0 0.3 GO:0000414 regulation of histone H3-K36 methylation(GO:0000414)
0.0 0.2 GO:1901731 positive regulation of platelet aggregation(GO:1901731)
0.0 0.4 GO:1902416 positive regulation of mRNA binding(GO:1902416)
0.0 0.4 GO:0030206 chondroitin sulfate biosynthetic process(GO:0030206)
0.0 0.3 GO:0035093 spermatogenesis, exchange of chromosomal proteins(GO:0035093)
0.0 0.3 GO:0032782 bile acid secretion(GO:0032782)
0.0 0.4 GO:0070475 rRNA base methylation(GO:0070475)
0.0 0.2 GO:0090309 positive regulation of methylation-dependent chromatin silencing(GO:0090309)
0.0 0.1 GO:0032289 central nervous system myelin formation(GO:0032289)
0.0 0.3 GO:0006682 galactosylceramide biosynthetic process(GO:0006682) galactolipid biosynthetic process(GO:0019375)
0.0 0.4 GO:0006824 cobalt ion transport(GO:0006824)
0.0 1.2 GO:0050873 brown fat cell differentiation(GO:0050873)
0.0 0.6 GO:0036295 cellular response to increased oxygen levels(GO:0036295)
0.0 0.1 GO:1903546 protein localization to photoreceptor outer segment(GO:1903546)
0.0 0.1 GO:0002188 translation reinitiation(GO:0002188)
0.0 0.4 GO:0014823 response to activity(GO:0014823)
0.0 0.3 GO:0034501 protein localization to kinetochore(GO:0034501)
0.0 0.4 GO:0051573 negative regulation of histone H3-K9 methylation(GO:0051573)
0.0 0.4 GO:0010566 regulation of ketone biosynthetic process(GO:0010566)
0.0 0.1 GO:1901837 negative regulation of transcription of nuclear large rRNA transcript from RNA polymerase I promoter(GO:1901837)
0.0 1.7 GO:0051965 positive regulation of synapse assembly(GO:0051965)
0.0 0.3 GO:0097094 craniofacial suture morphogenesis(GO:0097094)
0.0 0.2 GO:0030828 positive regulation of cGMP biosynthetic process(GO:0030828)
0.0 0.1 GO:0000056 ribosomal small subunit export from nucleus(GO:0000056)
0.0 0.1 GO:0033632 regulation of cell-cell adhesion mediated by integrin(GO:0033632)
0.0 2.1 GO:0050731 positive regulation of peptidyl-tyrosine phosphorylation(GO:0050731)
0.0 0.4 GO:0048791 calcium ion-regulated exocytosis of neurotransmitter(GO:0048791)
0.0 0.5 GO:0042551 neuron maturation(GO:0042551)
0.0 0.2 GO:0042407 cristae formation(GO:0042407)
0.0 0.4 GO:0000027 ribosomal large subunit assembly(GO:0000027)
0.0 0.2 GO:0006465 signal peptide processing(GO:0006465)
0.0 1.3 GO:0008286 insulin receptor signaling pathway(GO:0008286)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.3 GO:0033116 endoplasmic reticulum-Golgi intermediate compartment membrane(GO:0033116)
0.1 1.0 GO:0042613 MHC class II protein complex(GO:0042613)
0.1 1.5 GO:0031045 dense core granule(GO:0031045)
0.1 0.4 GO:0001652 granular component(GO:0001652)
0.1 1.0 GO:1902711 GABA-A receptor complex(GO:1902711)
0.0 0.4 GO:0071541 eukaryotic translation initiation factor 3 complex, eIF3m(GO:0071541)
0.0 0.5 GO:0097136 Bcl-2 family protein complex(GO:0097136)
0.0 0.2 GO:0005859 muscle myosin complex(GO:0005859)
0.0 0.8 GO:0097470 ribbon synapse(GO:0097470)
0.0 1.9 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.0 0.3 GO:0002177 manchette(GO:0002177)
0.0 1.3 GO:0005913 cell-cell adherens junction(GO:0005913)
0.0 0.6 GO:0016471 vacuolar proton-transporting V-type ATPase complex(GO:0016471)
0.0 1.3 GO:0032590 dendrite membrane(GO:0032590)
0.0 0.8 GO:0005865 striated muscle thin filament(GO:0005865) myofilament(GO:0036379)
0.0 0.2 GO:0097197 tetraspanin-enriched microdomain(GO:0097197)
0.0 0.3 GO:0000940 condensed chromosome outer kinetochore(GO:0000940)
0.0 0.4 GO:0072546 ER membrane protein complex(GO:0072546)
0.0 0.4 GO:0033655 host cell cytoplasm(GO:0030430) host cell cytoplasm part(GO:0033655)
0.0 0.4 GO:0031932 TORC2 complex(GO:0031932)
0.0 0.1 GO:0071817 MMXD complex(GO:0071817)
0.0 0.2 GO:0005787 signal peptidase complex(GO:0005787)
0.0 0.2 GO:0061617 MICOS complex(GO:0061617)
0.0 0.3 GO:0000276 mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276)
0.0 2.5 GO:0031225 anchored component of membrane(GO:0031225)
0.0 0.1 GO:0034448 EGO complex(GO:0034448)
0.0 1.5 GO:0001669 acrosomal vesicle(GO:0001669)
0.0 0.5 GO:0034451 centriolar satellite(GO:0034451)
0.0 0.3 GO:0005666 DNA-directed RNA polymerase III complex(GO:0005666)
0.0 0.3 GO:0016580 Sin3 complex(GO:0016580)
0.0 0.4 GO:0000795 synaptonemal complex(GO:0000795)
0.0 0.2 GO:0031143 pseudopodium(GO:0031143)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.1 GO:0008330 protein tyrosine/threonine phosphatase activity(GO:0008330)
0.1 0.4 GO:0008988 rRNA (adenine-N6-)-methyltransferase activity(GO:0008988) U6 snRNA 3'-end binding(GO:0030629)
0.1 0.8 GO:0009378 four-way junction helicase activity(GO:0009378)
0.1 0.4 GO:0047391 alkylglycerophosphoethanolamine phosphodiesterase activity(GO:0047391)
0.1 1.3 GO:0001618 virus receptor activity(GO:0001618)
0.1 0.8 GO:0016618 hydroxypyruvate reductase activity(GO:0016618) glyoxylate reductase (NADP) activity(GO:0030267)
0.1 0.4 GO:0016909 JUN kinase activity(GO:0004705) SAP kinase activity(GO:0016909)
0.1 0.8 GO:0005523 tropomyosin binding(GO:0005523)
0.1 0.7 GO:0008395 steroid hydroxylase activity(GO:0008395)
0.1 0.3 GO:0047275 glucosaminylgalactosylglucosylceramide beta-galactosyltransferase activity(GO:0047275)
0.1 0.3 GO:0015254 glycerol channel activity(GO:0015254)
0.1 0.3 GO:0043515 kinetochore binding(GO:0043515)
0.1 1.5 GO:0042056 chemoattractant activity(GO:0042056)
0.1 1.3 GO:0008188 neuropeptide receptor activity(GO:0008188)
0.1 0.3 GO:0046975 histone methyltransferase activity (H3-K36 specific)(GO:0046975)
0.1 1.5 GO:0031683 G-protein beta/gamma-subunit complex binding(GO:0031683)
0.1 1.0 GO:0004890 GABA-A receptor activity(GO:0004890)
0.1 0.6 GO:0008553 hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553)
0.1 0.5 GO:0051434 BH3 domain binding(GO:0051434)
0.0 0.2 GO:0051371 muscle alpha-actinin binding(GO:0051371)
0.0 0.4 GO:0015165 pyrimidine nucleotide-sugar transmembrane transporter activity(GO:0015165)
0.0 0.4 GO:0070180 large ribosomal subunit rRNA binding(GO:0070180)
0.0 0.4 GO:0015087 cobalt ion transmembrane transporter activity(GO:0015087)
0.0 0.4 GO:0015217 ATP transmembrane transporter activity(GO:0005347) ADP transmembrane transporter activity(GO:0015217)
0.0 0.8 GO:0043274 phospholipase binding(GO:0043274)
0.0 0.2 GO:0015250 water channel activity(GO:0015250)
0.0 1.9 GO:0043548 phosphatidylinositol 3-kinase binding(GO:0043548)
0.0 0.6 GO:0102391 decanoate--CoA ligase activity(GO:0102391)
0.0 1.5 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.0 0.3 GO:0004745 retinol dehydrogenase activity(GO:0004745)
0.0 0.4 GO:0005537 mannose binding(GO:0005537)
0.0 0.4 GO:0070403 NAD+ binding(GO:0070403)
0.0 0.2 GO:0001055 RNA polymerase II activity(GO:0001055)
0.0 1.2 GO:0046875 ephrin receptor binding(GO:0046875)
0.0 0.3 GO:0001848 complement binding(GO:0001848)
0.0 0.3 GO:0046933 proton-transporting ATP synthase activity, rotational mechanism(GO:0046933)
0.0 0.1 GO:0004984 olfactory receptor activity(GO:0004984)
0.0 0.4 GO:0070577 lysine-acetylated histone binding(GO:0070577)
0.0 0.1 GO:0043139 5'-3' DNA helicase activity(GO:0043139)
0.0 0.3 GO:0015020 glucuronosyltransferase activity(GO:0015020)
0.0 0.4 GO:0003887 DNA-directed DNA polymerase activity(GO:0003887)
0.0 0.1 GO:0016209 antioxidant activity(GO:0016209)
0.0 7.0 GO:0001228 transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001228)
0.0 0.4 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
0.0 1.4 GO:0005178 integrin binding(GO:0005178)
0.0 0.3 GO:0031489 myosin V binding(GO:0031489)
0.0 0.2 GO:0004383 guanylate cyclase activity(GO:0004383)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.9 PID_VEGF_VEGFR_PATHWAY VEGF and VEGFR signaling network
0.1 1.5 PID_LPA4_PATHWAY LPA4-mediated signaling events
0.0 1.3 PID_NECTIN_PATHWAY Nectin adhesion pathway
0.0 0.4 PID_RHODOPSIN_PATHWAY Visual signal transduction: Rods
0.0 2.1 PID_RET_PATHWAY Signaling events regulated by Ret tyrosine kinase
0.0 1.5 ST_JNK_MAPK_PATHWAY JNK MAPK Pathway
0.0 2.3 SIG_PIP3_SIGNALING_IN_CARDIAC_MYOCTES Genes related to PIP3 signaling in cardiac myocytes
0.0 0.8 PID_RHOA_REG_PATHWAY Regulation of RhoA activity
0.0 0.4 PID_TCPTP_PATHWAY Signaling events mediated by TCPTP

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.9 REACTOME_OLFACTORY_SIGNALING_PATHWAY Genes involved in Olfactory Signaling Pathway
0.2 1.9 REACTOME_VEGF_LIGAND_RECEPTOR_INTERACTIONS Genes involved in VEGF ligand-receptor interactions
0.1 0.7 REACTOME_ENDOGENOUS_STEROLS Genes involved in Endogenous sterols
0.1 1.1 REACTOME_ERKS_ARE_INACTIVATED Genes involved in ERKs are inactivated
0.1 0.6 REACTOME_GLUCURONIDATION Genes involved in Glucuronidation
0.1 1.0 REACTOME_GABA_A_RECEPTOR_ACTIVATION Genes involved in GABA A receptor activation
0.1 1.3 REACTOME_IMMUNOREGULATORY_INTERACTIONS_BETWEEN_A_LYMPHOID_AND_A_NON_LYMPHOID_CELL Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
0.0 2.1 REACTOME_NCAM1_INTERACTIONS Genes involved in NCAM1 interactions
0.0 0.4 REACTOME_BASE_FREE_SUGAR_PHOSPHATE_REMOVAL_VIA_THE_SINGLE_NUCLEOTIDE_REPLACEMENT_PATHWAY Genes involved in Base-free sugar-phosphate removal via the single-nucleotide replacement pathway
0.0 0.3 REACTOME_PASSIVE_TRANSPORT_BY_AQUAPORINS Genes involved in Passive Transport by Aquaporins
0.0 0.5 REACTOME_INFLAMMASOMES Genes involved in Inflammasomes
0.0 0.6 REACTOME_INSULIN_RECEPTOR_RECYCLING Genes involved in Insulin receptor recycling
0.0 0.4 REACTOME_ACTIVATION_OF_THE_AP1_FAMILY_OF_TRANSCRIPTION_FACTORS Genes involved in Activation of the AP-1 family of transcription factors
0.0 0.6 REACTOME_SYNTHESIS_OF_VERY_LONG_CHAIN_FATTY_ACYL_COAS Genes involved in Synthesis of very long-chain fatty acyl-CoAs
0.0 0.3 REACTOME_RNA_POL_III_CHAIN_ELONGATION Genes involved in RNA Polymerase III Chain Elongation
0.0 0.3 REACTOME_FORMATION_OF_ATP_BY_CHEMIOSMOTIC_COUPLING Genes involved in Formation of ATP by chemiosmotic coupling
0.0 0.2 REACTOME_SYNTHESIS_SECRETION_AND_INACTIVATION_OF_GIP Genes involved in Synthesis, Secretion, and Inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)
0.0 1.0 REACTOME_PEPTIDE_LIGAND_BINDING_RECEPTORS Genes involved in Peptide ligand-binding receptors
0.0 2.1 REACTOME_SIGNALING_BY_RHO_GTPASES Genes involved in Signaling by Rho GTPases