Motif ID: Foxn1

Z-value: 0.369


Transcription factors associated with Foxn1:

Gene SymbolEntrez IDGene Name
Foxn1 ENSMUSG00000002057.4 Foxn1



Activity profile for motif Foxn1.

activity profile for motif Foxn1


Sorted Z-values histogram for motif Foxn1

Sorted Z-values for motif Foxn1



Network of associatons between targets according to the STRING database.



First level regulatory network of Foxn1

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chrX_+_151803642 0.623 ENSMUST00000156616.2
 Huwe1
HECT, UBA and WWE domain containing 1
chr11_+_30771726 0.504 ENSMUST00000041231.7
 Psme4
proteasome (prosome, macropain) activator subunit 4
chrX_-_111463103 0.494 ENSMUST00000137712.2
 Rps6ka6
ribosomal protein S6 kinase polypeptide 6
chr6_+_38433913 0.482 ENSMUST00000160583.1
 Ubn2
ubinuclein 2
chr8_-_111876661 0.474 ENSMUST00000034431.1
 Tmem170
transmembrane protein 170
chr9_+_70207342 0.446 ENSMUST00000034745.7
 Myo1e
myosin IE
chr13_+_77135513 0.438 ENSMUST00000168779.1
 2210408I21Rik
RIKEN cDNA 2210408I21 gene
chr9_-_119578981 0.430 ENSMUST00000117911.1
ENSMUST00000120420.1
 Scn5a

sodium channel, voltage-gated, type V, alpha

chr17_+_86963279 0.421 ENSMUST00000139344.1
 Rhoq
ras homolog gene family, member Q
chr9_-_72985344 0.403 ENSMUST00000124565.2
 Gm5918
predicted gene 5918
chr17_+_6106464 0.395 ENSMUST00000142030.1
 Tulp4
tubby like protein 4
chr3_-_158562199 0.390 ENSMUST00000106044.1
 Lrrc7
leucine rich repeat containing 7
chr9_-_95750335 0.346 ENSMUST00000053785.3
 Trpc1
transient receptor potential cation channel, subfamily C, member 1
chrX_-_111463149 0.345 ENSMUST00000096348.3
ENSMUST00000113428.2
 Rps6ka6

ribosomal protein S6 kinase polypeptide 6

chr14_+_111675113 0.329 ENSMUST00000042767.7
 Slitrk5
SLIT and NTRK-like family, member 5
chr11_-_104550392 0.328 ENSMUST00000106962.2
 Cdc27
cell division cycle 27
chr14_+_75284343 0.302 ENSMUST00000022577.5
 Zc3h13
zinc finger CCCH type containing 13
chr3_-_116007399 0.289 ENSMUST00000067485.3
 Slc30a7
solute carrier family 30 (zinc transporter), member 7
chr6_+_149408973 0.279 ENSMUST00000086829.4
ENSMUST00000111513.2
 Bicd1

bicaudal D homolog 1 (Drosophila)

chr11_+_93996082 0.271 ENSMUST00000041956.7
 Spag9
sperm associated antigen 9
chr19_+_46152505 0.267 ENSMUST00000026254.7
 Gbf1
golgi-specific brefeldin A-resistance factor 1
chrX_-_111463043 0.265 ENSMUST00000065976.5
 Rps6ka6
ribosomal protein S6 kinase polypeptide 6
chr19_+_36834215 0.263 ENSMUST00000025729.5
 Tnks2
tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase 2
chr18_-_46525940 0.259 ENSMUST00000036226.5
 Fem1c
fem-1 homolog c (C.elegans)
chr14_+_63606491 0.257 ENSMUST00000119973.2
 Xkr6
X Kell blood group precursor related family member 6 homolog
chrX_-_74085656 0.256 ENSMUST00000033770.6
 Mecp2
methyl CpG binding protein 2
chr6_-_32588192 0.245 ENSMUST00000115096.2
 Plxna4
plexin A4
chr7_+_100372224 0.244 ENSMUST00000051777.8
ENSMUST00000098259.4
 C2cd3

C2 calcium-dependent domain containing 3

chr8_-_83332416 0.243 ENSMUST00000177594.1
ENSMUST00000053902.3
 Elmod2

ELMO/CED-12 domain containing 2

chr7_-_81829431 0.239 ENSMUST00000026093.7
 Btbd1
BTB (POZ) domain containing 1
chr11_-_104550460 0.238 ENSMUST00000106961.1
ENSMUST00000093923.2
 Cdc27

cell division cycle 27

chr13_-_64274879 0.223 ENSMUST00000109770.1
 Cdc14b
CDC14 cell division cycle 14B
chr1_-_161876656 0.221 ENSMUST00000048377.5
 Suco
SUN domain containing ossification factor
chrX_+_151803313 0.221 ENSMUST00000026292.8
 Huwe1
HECT, UBA and WWE domain containing 1
chr9_+_72985504 0.198 ENSMUST00000156879.1
 Ccpg1
cell cycle progression 1
chr16_-_96082389 0.195 ENSMUST00000099502.2
ENSMUST00000023631.8
ENSMUST00000113829.1
ENSMUST00000153398.1
 Brwd1



bromodomain and WD repeat domain containing 1



chr10_+_19934472 0.195 ENSMUST00000095806.3
ENSMUST00000120259.1
 Map3k5

mitogen-activated protein kinase kinase kinase 5

chr11_-_69758223 0.192 ENSMUST00000071213.3
 Polr2a
polymerase (RNA) II (DNA directed) polypeptide A
chr4_-_121215071 0.182 ENSMUST00000056635.5
 Rlf
rearranged L-myc fusion sequence
chrX_-_74085586 0.172 ENSMUST00000123362.1
ENSMUST00000140399.1
ENSMUST00000100750.3
 Mecp2


methyl CpG binding protein 2


chr14_-_57746044 0.167 ENSMUST00000173990.1
ENSMUST00000022531.7
 Lats2

large tumor suppressor 2

chr14_-_99099701 0.162 ENSMUST00000042471.9
 Dis3
DIS3 mitotic control homolog (S. cerevisiae)
chr1_-_178337774 0.160 ENSMUST00000037748.7
 Hnrnpu
heterogeneous nuclear ribonucleoprotein U
chr9_+_72985410 0.155 ENSMUST00000037977.8
 Ccpg1
cell cycle progression 1
chr11_+_67455339 0.152 ENSMUST00000108681.1
 Gas7
growth arrest specific 7
chr5_+_21424934 0.151 ENSMUST00000056045.4
 Fam185a
family with sequence similarity 185, member A
chr10_+_88379127 0.151 ENSMUST00000127615.1
 Gnptab
N-acetylglucosamine-1-phosphate transferase, alpha and beta subunits
chr12_-_105685235 0.150 ENSMUST00000041055.7
 Atg2b
autophagy related 2B
chr6_-_30896735 0.150 ENSMUST00000048774.6
ENSMUST00000166192.1
ENSMUST00000135230.1
 Copg2


coatomer protein complex, subunit gamma 2


chr8_-_11008458 0.148 ENSMUST00000040514.6
 Irs2
insulin receptor substrate 2
chr9_-_45984816 0.141 ENSMUST00000172450.1
 Pafah1b2
platelet-activating factor acetylhydrolase, isoform 1b, subunit 2
chr17_-_80062333 0.136 ENSMUST00000061331.7
 Hnrnpll
heterogeneous nuclear ribonucleoprotein L-like
chr2_-_125858985 0.135 ENSMUST00000110462.1
 Cops2
COP9 (constitutive photomorphogenic) homolog, subunit 2 (Arabidopsis thaliana)
chrX_+_99136119 0.134 ENSMUST00000052839.6
 Efnb1
ephrin B1
chr9_+_72985568 0.134 ENSMUST00000150826.2
ENSMUST00000085350.4
ENSMUST00000140675.1
 Ccpg1


cell cycle progression 1


chr4_+_40722461 0.132 ENSMUST00000030118.3
 Dnaja1
DnaJ (Hsp40) homolog, subfamily A, member 1
chr8_+_60993189 0.124 ENSMUST00000034065.7
ENSMUST00000120689.1
 Nek1

NIMA (never in mitosis gene a)-related expressed kinase 1

chr4_+_116558056 0.121 ENSMUST00000106475.1
 Gpbp1l1
GC-rich promoter binding protein 1-like 1
chr12_+_86082555 0.119 ENSMUST00000054565.6
 Ift43
intraflagellar transport 43 homolog (Chlamydomonas)
chr13_-_64274962 0.115 ENSMUST00000039318.8
 Cdc14b
CDC14 cell division cycle 14B
chr4_+_40722912 0.111 ENSMUST00000164233.1
ENSMUST00000137246.1
ENSMUST00000125442.1
 Dnaja1


DnaJ (Hsp40) homolog, subfamily A, member 1


chr11_-_69758630 0.111 ENSMUST00000058470.9
 Polr2a
polymerase (RNA) II (DNA directed) polypeptide A
chr6_-_134792596 0.109 ENSMUST00000100857.3
 Dusp16
dual specificity phosphatase 16
chr5_+_130171798 0.108 ENSMUST00000119797.1
ENSMUST00000148264.1
 Rabgef1

RAB guanine nucleotide exchange factor (GEF) 1

chr18_-_37935378 0.106 ENSMUST00000025337.7
 Diap1
diaphanous homolog 1 (Drosophila)
chr2_+_110017879 0.105 ENSMUST00000150183.2
 Ccdc34
coiled-coil domain containing 34
chr13_-_77135416 0.102 ENSMUST00000159462.1
ENSMUST00000151524.2
 Ankrd32

ankyrin repeat domain 32

chr1_+_127868773 0.100 ENSMUST00000037649.5
 Rab3gap1
RAB3 GTPase activating protein subunit 1
chr9_+_69989466 0.100 ENSMUST00000034754.5
ENSMUST00000085393.6
ENSMUST00000117450.1
 Bnip2


BCL2/adenovirus E1B interacting protein 2


chr7_-_133776681 0.088 ENSMUST00000130182.1
ENSMUST00000106139.1
 Dhx32

DEAH (Asp-Glu-Ala-His) box polypeptide 32

chr6_-_39725448 0.085 ENSMUST00000002487.8
 Braf
Braf transforming gene
chr1_+_178405881 0.084 ENSMUST00000027775.7
 Efcab2
EF-hand calcium binding domain 2
chr2_-_125859139 0.084 ENSMUST00000110463.1
ENSMUST00000028635.5
 Cops2

COP9 (constitutive photomorphogenic) homolog, subunit 2 (Arabidopsis thaliana)

chr4_+_116557658 0.083 ENSMUST00000030460.8
 Gpbp1l1
GC-rich promoter binding protein 1-like 1
chr2_+_110017806 0.079 ENSMUST00000028580.5
 Ccdc34
coiled-coil domain containing 34
chr9_-_64737623 0.078 ENSMUST00000169058.1
 Rab11a
RAB11a, member RAS oncogene family
chr7_-_133776772 0.077 ENSMUST00000033290.5
 Dhx32
DEAH (Asp-Glu-Ala-His) box polypeptide 32
chr18_-_10610048 0.077 ENSMUST00000115864.1
 Esco1
establishment of cohesion 1 homolog 1 (S. cerevisiae)
chrX_-_74249819 0.065 ENSMUST00000114299.1
 Flna
filamin, alpha
chr2_+_125859134 0.064 ENSMUST00000028636.6
ENSMUST00000125084.1
 Galk2

galactokinase 2

chr6_+_28480337 0.064 ENSMUST00000001460.7
ENSMUST00000167201.1
 Snd1

staphylococcal nuclease and tudor domain containing 1

chr9_-_75683992 0.063 ENSMUST00000034699.6
 Scg3
secretogranin III
chr15_-_101054399 0.053 ENSMUST00000178140.1
 Fignl2
fidgetin-like 2
chr11_-_120348475 0.053 ENSMUST00000062147.7
ENSMUST00000128055.1
 Actg1

actin, gamma, cytoplasmic 1

chr8_-_94012120 0.052 ENSMUST00000143265.1
 Amfr
autocrine motility factor receptor
chr3_+_152210458 0.051 ENSMUST00000166984.1
ENSMUST00000106121.1
 Fubp1

far upstream element (FUSE) binding protein 1

chr1_-_155099630 0.049 ENSMUST00000055322.4
 Ier5
immediate early response 5
chr10_+_88379217 0.048 ENSMUST00000130301.1
ENSMUST00000020251.8
 Gnptab

N-acetylglucosamine-1-phosphate transferase, alpha and beta subunits

chr8_+_105636509 0.047 ENSMUST00000005841.9
 Ctcf
CCCTC-binding factor
chr19_+_43612299 0.047 ENSMUST00000057178.9
 Nkx2-3
NK2 homeobox 3
chr11_-_116131073 0.047 ENSMUST00000106440.2
ENSMUST00000067632.3
 Trim65

tripartite motif-containing 65

chrX_+_101429555 0.044 ENSMUST00000033673.6
 Nono
non-POU-domain-containing, octamer binding protein
chr9_-_64737684 0.041 ENSMUST00000171100.1
ENSMUST00000167569.1
ENSMUST00000004892.6
ENSMUST00000172298.1
 Rab11a



RAB11a, member RAS oncogene family



chr12_+_105685352 0.041 ENSMUST00000051934.5
 Gskip
GSK3B interacting protein
chr4_+_122836236 0.037 ENSMUST00000030412.4
ENSMUST00000121870.1
ENSMUST00000097902.4
 Ppt1


palmitoyl-protein thioesterase 1


chr7_+_133776857 0.034 ENSMUST00000065359.5
ENSMUST00000151031.1
ENSMUST00000121560.1
 Fank1


fibronectin type 3 and ankyrin repeat domains 1


chr2_+_181497223 0.034 ENSMUST00000108799.3
 Tpd52l2
tumor protein D52-like 2
chr17_-_80062199 0.030 ENSMUST00000184635.1
 Hnrnpll
heterogeneous nuclear ribonucleoprotein L-like
chr5_-_115300957 0.028 ENSMUST00000009157.3
 Dynll1
dynein light chain LC8-type 1
chr11_-_50210765 0.028 ENSMUST00000143379.1
ENSMUST00000015981.5
ENSMUST00000102774.4
 Sqstm1


sequestosome 1


chr2_+_131210501 0.008 ENSMUST00000110206.1
 Ap5s1
adaptor-related protein 5 complex, sigma 1 subunit
chr5_-_115300912 0.006 ENSMUST00000112090.1
 Dynll1
dynein light chain LC8-type 1
chr3_+_103020546 0.006 ENSMUST00000029446.8
 Csde1
cold shock domain containing E1, RNA binding
chr1_+_59119822 0.006 ENSMUST00000180570.1
 G730003C15Rik
RIKEN cDNA G730003C15 gene
chr2_+_181497165 0.004 ENSMUST00000149163.1
ENSMUST00000000844.8
ENSMUST00000184849.1
ENSMUST00000108800.1
ENSMUST00000069712.2
 Tpd52l2




tumor protein D52-like 2





Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 GO:0014877 response to inactivity(GO:0014854) response to muscle inactivity(GO:0014870) response to muscle inactivity involved in regulation of muscle adaptation(GO:0014877) response to denervation involved in regulation of muscle adaptation(GO:0014894) membrane depolarization during Purkinje myocyte cell action potential(GO:0086047)
0.1 0.4 GO:1901608 dense core granule localization(GO:0032253) cellular response to isoquinoline alkaloid(GO:0071317) regulation of vesicle transport along microtubule(GO:1901608) dense core granule transport(GO:1901950) regulation of dense core granule transport(GO:1904809) positive regulation of dense core granule transport(GO:1904811)
0.1 0.5 GO:0010499 proteasomal ubiquitin-independent protein catabolic process(GO:0010499)
0.1 0.5 GO:2001106 regulation of Rho guanyl-nucleotide exchange factor activity(GO:2001106)
0.1 0.3 GO:1900275 negative regulation of phospholipase C activity(GO:1900275)
0.1 0.3 GO:0070973 COPI-coated vesicle budding(GO:0035964) protein localization to endoplasmic reticulum exit site(GO:0070973)
0.1 1.1 GO:2000381 negative regulation of mesoderm development(GO:2000381)
0.1 0.4 GO:0035166 post-embryonic hemopoiesis(GO:0035166)
0.1 0.2 GO:0016256 N-glycan processing to lysosome(GO:0016256)
0.1 0.3 GO:0070213 protein auto-ADP-ribosylation(GO:0070213)
0.1 0.2 GO:0021564 glossopharyngeal nerve development(GO:0021563) vagus nerve development(GO:0021564)
0.1 0.2 GO:0001828 inner cell mass cell fate commitment(GO:0001827) inner cell mass cellular morphogenesis(GO:0001828)
0.1 0.2 GO:2000373 regulation of DNA topoisomerase (ATP-hydrolyzing) activity(GO:2000371) positive regulation of DNA topoisomerase (ATP-hydrolyzing) activity(GO:2000373)
0.1 0.1 GO:1903371 regulation of endoplasmic reticulum tubular network organization(GO:1903371)
0.0 0.2 GO:0061511 centriole elongation(GO:0061511)
0.0 0.4 GO:0042769 DNA damage response, detection of DNA damage(GO:0042769)
0.0 0.2 GO:0071034 CUT catabolic process(GO:0071034) CUT metabolic process(GO:0071043)
0.0 0.3 GO:0046541 saliva secretion(GO:0046541)
0.0 0.3 GO:0090074 negative regulation of protein homodimerization activity(GO:0090074)
0.0 0.5 GO:0051292 nuclear pore complex assembly(GO:0051292)
0.0 0.3 GO:1904668 mitotic spindle midzone assembly(GO:0051256) positive regulation of ubiquitin protein ligase activity(GO:1904668)
0.0 0.3 GO:0061088 sequestering of zinc ion(GO:0032119) regulation of sequestering of zinc ion(GO:0061088)
0.0 0.1 GO:0010796 regulation of multivesicular body size(GO:0010796) multivesicular body assembly(GO:0036258)
0.0 0.1 GO:0036216 response to stem cell factor(GO:0036215) cellular response to stem cell factor stimulus(GO:0036216) Kit signaling pathway(GO:0038109) regulation of Fc receptor mediated stimulatory signaling pathway(GO:0060368)
0.0 0.2 GO:0015074 DNA integration(GO:0015074)
0.0 0.1 GO:1905000 regulation of membrane repolarization during atrial cardiac muscle cell action potential(GO:1905000)
0.0 0.6 GO:0070979 protein K11-linked ubiquitination(GO:0070979)
0.0 0.8 GO:0006284 base-excision repair(GO:0006284)
0.0 0.1 GO:0002903 negative regulation of B cell apoptotic process(GO:0002903)
0.0 0.1 GO:0034421 post-translational protein acetylation(GO:0034421)
0.0 0.3 GO:0006353 DNA-templated transcription, termination(GO:0006353)
0.0 0.3 GO:0021756 striatum development(GO:0021756)
0.0 0.4 GO:0030866 cortical actin cytoskeleton organization(GO:0030866)
0.0 0.2 GO:1902170 cellular response to reactive nitrogen species(GO:1902170)
0.0 0.2 GO:0000338 protein deneddylation(GO:0000338)
0.0 0.1 GO:0031047 gene silencing by RNA(GO:0031047)
0.0 0.1 GO:0002318 myeloid progenitor cell differentiation(GO:0002318)
0.0 0.4 GO:0061512 protein localization to cilium(GO:0061512)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.5 GO:1990111 spermatoproteasome complex(GO:1990111)
0.1 0.4 GO:0032437 cuticular plate(GO:0032437)
0.0 0.2 GO:1990604 IRE1-TRAF2-ASK1 complex(GO:1990604)
0.0 0.3 GO:0033648 host intracellular organelle(GO:0033647) host intracellular membrane-bounded organelle(GO:0033648)
0.0 0.4 GO:0001518 voltage-gated sodium channel complex(GO:0001518)
0.0 0.2 GO:0070937 CRD-mediated mRNA stability complex(GO:0070937)
0.0 0.6 GO:0005680 anaphase-promoting complex(GO:0005680)
0.0 0.3 GO:0000974 Prp19 complex(GO:0000974)
0.0 0.4 GO:0000242 pericentriolar material(GO:0000242)
0.0 0.1 GO:0005828 kinetochore microtubule(GO:0005828)
0.0 0.4 GO:0000930 gamma-tubulin complex(GO:0000930)
0.0 0.2 GO:0000176 nuclear exosome (RNase complex)(GO:0000176)
0.0 0.1 GO:0030991 intraciliary transport particle A(GO:0030991)
0.0 0.1 GO:0031523 Myb complex(GO:0031523)
0.0 0.1 GO:0030126 COPI vesicle coat(GO:0030126)
0.0 0.2 GO:0034451 centriolar satellite(GO:0034451)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 GO:0031871 proteinase activated receptor binding(GO:0031871)
0.1 0.4 GO:0010385 double-stranded methylated DNA binding(GO:0010385)
0.1 0.4 GO:0086006 voltage-gated sodium channel activity involved in cardiac muscle cell action potential(GO:0086006)
0.0 0.2 GO:0003976 UDP-N-acetylglucosamine-lysosomal-enzyme N-acetylglucosaminephosphotransferase activity(GO:0003976)
0.0 0.4 GO:0005522 profilin binding(GO:0005522)
0.0 0.2 GO:0055131 C3HC4-type RING finger domain binding(GO:0055131)
0.0 0.3 GO:0001055 RNA polymerase II activity(GO:0001055)
0.0 0.3 GO:0015279 store-operated calcium channel activity(GO:0015279)
0.0 0.1 GO:0004335 galactokinase activity(GO:0004335)
0.0 0.5 GO:0070577 lysine-acetylated histone binding(GO:0070577)
0.0 0.3 GO:0048273 mitogen-activated protein kinase p38 binding(GO:0048273)
0.0 0.2 GO:0034046 poly(G) binding(GO:0034046)
0.0 0.2 GO:0017154 semaphorin receptor activity(GO:0017154)
0.0 0.1 GO:0034988 Fc-gamma receptor I complex binding(GO:0034988)
0.0 0.3 GO:0003950 NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.0 0.3 GO:0004709 MAP kinase kinase kinase activity(GO:0004709)
0.0 0.3 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.0 0.3 GO:0080025 phosphatidylinositol-3,5-bisphosphate binding(GO:0080025)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 SA_G2_AND_M_PHASES Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
0.0 0.4 PID_INSULIN_GLUCOSE_PATHWAY Insulin-mediated glucose transport
0.0 0.8 PID_P53_REGULATION_PATHWAY p53 pathway

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.6 REACTOME_CONVERSION_FROM_APC_C_CDC20_TO_APC_C_CDH1_IN_LATE_ANAPHASE Genes involved in Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase
0.0 1.1 REACTOME_RECYCLING_PATHWAY_OF_L1 Genes involved in Recycling pathway of L1
0.0 0.3 REACTOME_COPI_MEDIATED_TRANSPORT Genes involved in COPI Mediated Transport
0.0 0.3 REACTOME_VIRAL_MESSENGER_RNA_SYNTHESIS Genes involved in Viral Messenger RNA Synthesis
0.0 0.1 REACTOME_SIGNALLING_TO_P38_VIA_RIT_AND_RIN Genes involved in Signalling to p38 via RIT and RIN
0.0 0.3 REACTOME_ZINC_TRANSPORTERS Genes involved in Zinc transporters
0.0 0.2 REACTOME_MRNA_DECAY_BY_3_TO_5_EXORIBONUCLEASE Genes involved in mRNA Decay by 3' to 5' Exoribonuclease