Motif ID: Gata3

Z-value: 1.786


Transcription factors associated with Gata3:

Gene SymbolEntrez IDGene Name
Gata3 ENSMUSG00000015619.10 Gata3

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Gata3mm10_v2_chr2_-_9890026_9890035-0.607.5e-05Click!


Activity profile for motif Gata3.

activity profile for motif Gata3


Sorted Z-values histogram for motif Gata3

Sorted Z-values for motif Gata3



Network of associatons between targets according to the STRING database.



First level regulatory network of Gata3

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr1_-_119053339 17.995 ENSMUST00000161301.1
ENSMUST00000161451.1
ENSMUST00000162607.1
Gli2


GLI-Kruppel family member GLI2


chr1_-_119053619 13.915 ENSMUST00000062483.8
Gli2
GLI-Kruppel family member GLI2
chr6_-_23248264 11.177 ENSMUST00000031709.5
Fezf1
Fez family zinc finger 1
chr11_+_102604370 9.671 ENSMUST00000057893.5
Fzd2
frizzled homolog 2 (Drosophila)
chr4_-_117178726 8.714 ENSMUST00000153953.1
ENSMUST00000106436.1
Kif2c

kinesin family member 2C

chr1_+_6730051 8.540 ENSMUST00000043578.6
ENSMUST00000131467.1
ENSMUST00000150761.1
ENSMUST00000151281.1
St18



suppression of tumorigenicity 18



chr3_+_102010138 8.288 ENSMUST00000066187.4
Nhlh2
nescient helix loop helix 2
chr14_+_67234620 8.060 ENSMUST00000176029.1
Ebf2
early B cell factor 2
chr16_-_50432340 7.198 ENSMUST00000066037.6
ENSMUST00000089399.4
ENSMUST00000089404.3
ENSMUST00000114477.1
ENSMUST00000138166.1
Bbx




bobby sox homolog (Drosophila)




chr4_+_148041172 6.998 ENSMUST00000069604.8
Mthfr
5,10-methylenetetrahydrofolate reductase
chr7_-_116031047 6.984 ENSMUST00000106612.1
Sox6
SRY-box containing gene 6
chr7_-_103853199 6.947 ENSMUST00000033229.3
Hbb-y
hemoglobin Y, beta-like embryonic chain
chr2_+_25372315 6.843 ENSMUST00000028329.6
ENSMUST00000114293.2
ENSMUST00000100323.2
Sapcd2


suppressor APC domain containing 2


chr7_-_37772868 6.755 ENSMUST00000176205.1
Zfp536
zinc finger protein 536
chr9_+_65265173 6.679 ENSMUST00000048762.1
Cilp
cartilage intermediate layer protein, nucleotide pyrophosphohydrolase
chr11_+_32276400 6.242 ENSMUST00000020531.2
Hba-x
hemoglobin X, alpha-like embryonic chain in Hba complex
chr6_-_48840988 6.217 ENSMUST00000164733.1
Tmem176b
transmembrane protein 176B
chr6_-_48841098 6.199 ENSMUST00000101429.4
Tmem176b
transmembrane protein 176B
chr4_-_117182623 6.169 ENSMUST00000065896.2
Kif2c
kinesin family member 2C
chr4_+_9269285 6.121 ENSMUST00000038841.7
Clvs1
clavesin 1
chr14_+_13453937 6.094 ENSMUST00000153954.1
Synpr
synaptoporin
chr1_+_6730135 6.081 ENSMUST00000155921.1
St18
suppression of tumorigenicity 18
chr10_-_42583628 6.039 ENSMUST00000019938.4
Nr2e1
nuclear receptor subfamily 2, group E, member 1
chr6_-_48841373 5.957 ENSMUST00000166247.1
Tmem176b
transmembrane protein 176B
chr7_-_115846080 5.917 ENSMUST00000166207.1
Sox6
SRY-box containing gene 6
chr15_-_75747922 5.729 ENSMUST00000062002.4
Mafa
v-maf musculoaponeurotic fibrosarcoma oncogene family, protein A (avian)
chr7_-_116038734 5.583 ENSMUST00000166877.1
Sox6
SRY-box containing gene 6
chr6_+_48841476 5.536 ENSMUST00000101426.4
Tmem176a
transmembrane protein 176A
chr6_+_48841633 5.465 ENSMUST00000168406.1
Tmem176a
transmembrane protein 176A
chr11_+_32276893 5.333 ENSMUST00000145569.1
Hba-x
hemoglobin X, alpha-like embryonic chain in Hba complex
chr8_-_61591130 5.320 ENSMUST00000135439.1
ENSMUST00000121200.1
Palld

palladin, cytoskeletal associated protein

chr14_+_13454010 5.178 ENSMUST00000112656.2
Synpr
synaptoporin
chr11_-_100527862 5.117 ENSMUST00000107385.1
Acly
ATP citrate lyase
chr19_+_41482632 5.030 ENSMUST00000067795.5
Lcor
ligand dependent nuclear receptor corepressor
chr7_-_115824699 4.931 ENSMUST00000169129.1
Sox6
SRY-box containing gene 6
chr9_-_72491939 4.819 ENSMUST00000185151.1
ENSMUST00000085358.5
ENSMUST00000184125.1
ENSMUST00000183574.1
ENSMUST00000184831.1
Tex9




testis expressed gene 9




chr4_-_110286581 4.813 ENSMUST00000138972.1
Elavl4
ELAV (embryonic lethal, abnormal vision, Drosophila)-like 4 (Hu antigen D)
chr19_+_38931008 4.798 ENSMUST00000145051.1
Hells
helicase, lymphoid specific
chr17_-_35702297 4.664 ENSMUST00000135078.1
Ddr1
discoidin domain receptor family, member 1
chrX_-_145505175 4.523 ENSMUST00000143610.1
Amot
angiomotin
chr19_+_38930909 4.409 ENSMUST00000025965.5
Hells
helicase, lymphoid specific
chr6_-_99666762 4.408 ENSMUST00000032151.2
Eif4e3
eukaryotic translation initiation factor 4E member 3
chr5_+_115908644 4.388 ENSMUST00000141101.1
Cit
citron
chr8_+_45507768 4.377 ENSMUST00000067065.7
ENSMUST00000098788.3
ENSMUST00000067107.7
ENSMUST00000171337.2
ENSMUST00000138049.1
ENSMUST00000141039.1
Sorbs2





sorbin and SH3 domain containing 2





chr8_-_122699066 4.370 ENSMUST00000127984.1
Cbfa2t3
core-binding factor, runt domain, alpha subunit 2, translocated to, 3 (human)
chr1_+_153665666 4.303 ENSMUST00000111814.1
ENSMUST00000111810.1
Rgs8

regulator of G-protein signaling 8

chrX_-_145505136 4.289 ENSMUST00000112835.1
Amot
angiomotin
chr5_+_115845229 4.282 ENSMUST00000137952.1
ENSMUST00000148245.1
Cit

citron

chr2_+_121289589 4.255 ENSMUST00000094639.3
Map1a
microtubule-associated protein 1 A
chr8_+_45627709 4.244 ENSMUST00000134321.1
ENSMUST00000135336.1
Sorbs2

sorbin and SH3 domain containing 2

chr2_-_84775388 4.239 ENSMUST00000023994.3
Serping1
serine (or cysteine) peptidase inhibitor, clade G, member 1
chr11_-_100527896 4.117 ENSMUST00000107389.1
ENSMUST00000007131.9
Acly

ATP citrate lyase

chr13_-_97747399 4.054 ENSMUST00000144993.1
5330416C01Rik
RIKEN cDNA 5330416C01 gene
chr17_-_57078490 3.988 ENSMUST00000011623.7
Dennd1c
DENN/MADD domain containing 1C
chr19_-_30175414 3.967 ENSMUST00000025778.7
Gldc
glycine decarboxylase
chr4_+_116708571 3.942 ENSMUST00000106462.2
ENSMUST00000138305.1
ENSMUST00000125671.1
ENSMUST00000130828.1
Ccdc163



coiled-coil domain containing 163



chr16_-_36784924 3.942 ENSMUST00000168279.1
ENSMUST00000164579.1
ENSMUST00000023616.2
Slc15a2


solute carrier family 15 (H+/peptide transporter), member 2


chr2_+_163054682 3.916 ENSMUST00000018005.3
Mybl2
myeloblastosis oncogene-like 2
chr1_+_82233112 3.904 ENSMUST00000023262.5
Gm9747
predicted gene 9747
chr8_+_45628176 3.904 ENSMUST00000130850.1
Sorbs2
sorbin and SH3 domain containing 2
chr10_-_92162753 3.881 ENSMUST00000182197.1
Rmst
rhabdomyosarcoma 2 associated transcript (non-coding RNA)
chr2_+_181767283 3.866 ENSMUST00000108757.2
Myt1
myelin transcription factor 1
chr7_+_45216671 3.842 ENSMUST00000134420.1
Tead2
TEA domain family member 2
chr4_-_130279205 3.835 ENSMUST00000120126.2
Serinc2
serine incorporator 2
chr9_+_122951051 3.831 ENSMUST00000040717.5
Kif15
kinesin family member 15
chr6_+_124830217 3.825 ENSMUST00000131847.1
ENSMUST00000151674.1
Cdca3

cell division cycle associated 3

chr19_-_24861828 3.813 ENSMUST00000047666.4
Pgm5
phosphoglucomutase 5
chrX_+_100625737 3.778 ENSMUST00000048962.3
Kif4
kinesin family member 4
chr6_+_15196949 3.753 ENSMUST00000151301.1
ENSMUST00000131414.1
ENSMUST00000140557.1
ENSMUST00000115469.1
Foxp2



forkhead box P2



chr8_+_45627946 3.744 ENSMUST00000145458.1
Sorbs2
sorbin and SH3 domain containing 2
chr13_-_97747373 3.701 ENSMUST00000123535.1
5330416C01Rik
RIKEN cDNA 5330416C01 gene
chr7_+_75610038 3.632 ENSMUST00000125771.1
Akap13
A kinase (PRKA) anchor protein 13
chr6_-_72235559 3.617 ENSMUST00000042646.7
Atoh8
atonal homolog 8 (Drosophila)
chr8_+_94984399 3.609 ENSMUST00000093271.6
Gpr56
G protein-coupled receptor 56
chr18_+_82910863 3.581 ENSMUST00000171238.1
Zfp516
zinc finger protein 516
chr17_+_78491549 3.569 ENSMUST00000079363.4
Gm10093
predicted pseudogene 10093
chr7_-_98145472 3.533 ENSMUST00000098281.2
Omp
olfactory marker protein
chr10_-_75643971 3.526 ENSMUST00000095541.3
ENSMUST00000077610.4
Susd2

sushi domain containing 2

chr2_-_84775420 3.459 ENSMUST00000111641.1
Serping1
serine (or cysteine) peptidase inhibitor, clade G, member 1
chr8_-_89044162 3.435 ENSMUST00000034090.6
Sall1
sal-like 1 (Drosophila)
chr6_+_120666388 3.421 ENSMUST00000112686.1
Cecr2
cat eye syndrome chromosome region, candidate 2
chr2_+_84839395 3.414 ENSMUST00000146816.1
ENSMUST00000028469.7
Slc43a1

solute carrier family 43, member 1

chr7_-_75308373 3.398 ENSMUST00000085164.5
Sv2b
synaptic vesicle glycoprotein 2 b
chr11_-_115808068 3.366 ENSMUST00000132780.1
Caskin2
CASK-interacting protein 2
chr7_-_103843154 3.364 ENSMUST00000063957.4
Hbb-bh1
hemoglobin Z, beta-like embryonic chain
chr2_+_181767040 3.360 ENSMUST00000108756.1
Myt1
myelin transcription factor 1
chr4_+_116708624 3.281 ENSMUST00000106463.1
Ccdc163
coiled-coil domain containing 163
chr11_+_44617310 3.263 ENSMUST00000081265.5
ENSMUST00000101326.3
ENSMUST00000109268.1
Ebf1


early B cell factor 1


chr7_-_49636847 3.243 ENSMUST00000032717.6
Dbx1
developing brain homeobox 1
chr6_-_95718800 3.240 ENSMUST00000079847.5
Suclg2
succinate-Coenzyme A ligase, GDP-forming, beta subunit
chr1_+_153665587 3.239 ENSMUST00000147700.1
Rgs8
regulator of G-protein signaling 8
chr2_-_118547541 3.217 ENSMUST00000110859.2
Bmf
BCL2 modifying factor
chr2_-_172043466 3.215 ENSMUST00000087950.3
Cbln4
cerebellin 4 precursor protein
chr7_+_112742025 3.184 ENSMUST00000164363.1
Tead1
TEA domain family member 1
chr2_-_172370506 3.142 ENSMUST00000109139.1
ENSMUST00000028997.7
ENSMUST00000109140.3
Aurka


aurora kinase A


chr12_-_10900296 3.114 ENSMUST00000085735.2
Pgk1-rs7
phosphoglycerate kinase-1, related sequence-7
chr7_+_75455534 3.100 ENSMUST00000147005.1
ENSMUST00000166315.1
Akap13

A kinase (PRKA) anchor protein 13

chr11_+_97030130 3.081 ENSMUST00000153482.1
Scrn2
secernin 2
chr12_+_52516077 3.069 ENSMUST00000110725.1
Arhgap5
Rho GTPase activating protein 5
chr1_+_153665627 3.058 ENSMUST00000147482.1
Rgs8
regulator of G-protein signaling 8
chr13_-_89742490 3.041 ENSMUST00000109546.2
Vcan
versican
chr7_-_142899985 2.961 ENSMUST00000000219.3
Th
tyrosine hydroxylase
chr17_-_35702040 2.936 ENSMUST00000166980.2
ENSMUST00000145900.1
Ddr1

discoidin domain receptor family, member 1

chr9_-_37613715 2.929 ENSMUST00000002013.9
Spa17
sperm autoantigenic protein 17
chr11_+_117849286 2.920 ENSMUST00000093906.4
Birc5
baculoviral IAP repeat-containing 5
chr9_-_97018823 2.901 ENSMUST00000055433.4
Spsb4
splA/ryanodine receptor domain and SOCS box containing 4
chr4_-_83285141 2.802 ENSMUST00000150522.1
Ttc39b
tetratricopeptide repeat domain 39B
chr5_-_99252839 2.798 ENSMUST00000168092.1
ENSMUST00000031276.8
Rasgef1b

RasGEF domain family, member 1B

chr6_-_39206782 2.766 ENSMUST00000002305.8
Jhdm1d
jumonji C domain-containing histone demethylase 1 homolog D (S. cerevisiae)
chr9_+_109096659 2.742 ENSMUST00000130366.1
Plxnb1
plexin B1
chr9_-_44234014 2.729 ENSMUST00000037644.6
Cbl
Casitas B-lineage lymphoma
chr4_-_63662910 2.720 ENSMUST00000184252.1
Gm11214
predicted gene 11214
chr11_+_95337012 2.720 ENSMUST00000037502.6
Fam117a
family with sequence similarity 117, member A
chrX_-_108834303 2.682 ENSMUST00000101283.3
ENSMUST00000150434.1
Brwd3

bromodomain and WD repeat domain containing 3

chr7_+_51879041 2.665 ENSMUST00000107591.2
Gas2
growth arrest specific 2
chr5_+_127241807 2.657 ENSMUST00000119026.1
Tmem132c
transmembrane protein 132C
chr6_+_124829582 2.644 ENSMUST00000024270.7
Cdca3
cell division cycle associated 3
chr8_+_127064022 2.644 ENSMUST00000160272.1
ENSMUST00000079777.5
ENSMUST00000162907.1
Pard3


par-3 (partitioning defective 3) homolog (C. elegans)


chr7_+_51878967 2.642 ENSMUST00000051912.6
Gas2
growth arrest specific 2
chr5_+_110135823 2.627 ENSMUST00000112519.2
ENSMUST00000014812.8
Chfr

checkpoint with forkhead and ring finger domains

chr2_-_118762607 2.611 ENSMUST00000059997.8
A430105I19Rik
RIKEN cDNA A430105I19 gene
chr7_+_144915100 2.574 ENSMUST00000128057.1
Oraov1
oral cancer overexpressed 1
chr5_-_116591811 2.549 ENSMUST00000076124.5
Srrm4
serine/arginine repetitive matrix 4
chr8_+_127064107 2.542 ENSMUST00000162536.1
ENSMUST00000026921.6
ENSMUST00000162665.1
ENSMUST00000160766.1
ENSMUST00000162602.1
ENSMUST00000162531.1
ENSMUST00000160581.1
ENSMUST00000161355.1
ENSMUST00000159537.1
Pard3








par-3 (partitioning defective 3) homolog (C. elegans)








chr17_+_35049966 2.539 ENSMUST00000007257.9
Clic1
chloride intracellular channel 1
chrX_+_71050160 2.524 ENSMUST00000082088.3
ENSMUST00000114629.3
Mamld1

mastermind-like domain containing 1

chr8_+_127063893 2.505 ENSMUST00000162309.1
Pard3
par-3 (partitioning defective 3) homolog (C. elegans)
chr9_+_72438534 2.497 ENSMUST00000034746.8
Mns1
meiosis-specific nuclear structural protein 1
chr4_-_110292719 2.491 ENSMUST00000106601.1
Elavl4
ELAV (embryonic lethal, abnormal vision, Drosophila)-like 4 (Hu antigen D)
chr14_-_34374617 2.479 ENSMUST00000023826.4
Sncg
synuclein, gamma
chr10_+_41519493 2.472 ENSMUST00000019962.8
Cd164
CD164 antigen
chr17_+_80944611 2.467 ENSMUST00000025092.4
Tmem178
transmembrane protein 178
chr2_+_33216051 2.456 ENSMUST00000004208.5
Angptl2
angiopoietin-like 2
chr17_-_8566869 2.446 ENSMUST00000184183.1
Gm17087
predicted gene 17087
chr17_-_46629420 2.445 ENSMUST00000044442.8
Ptk7
PTK7 protein tyrosine kinase 7
chr1_+_109993982 2.444 ENSMUST00000027542.6
Cdh7
cadherin 7, type 2
chr2_-_64097994 2.437 ENSMUST00000131615.2
Fign
fidgetin
chr4_+_43669610 2.434 ENSMUST00000107866.1
Tmem8b
transmembrane protein 8B
chr11_+_94741782 2.428 ENSMUST00000021240.6
Cdc34-ps
cell division cycle 34 homolog, pseudogene (S. cerevisiae)
chr11_-_115813621 2.426 ENSMUST00000041684.4
ENSMUST00000156812.1
Caskin2

CASK-interacting protein 2

chr8_-_8639363 2.413 ENSMUST00000152698.1
Efnb2
ephrin B2
chr5_-_44099220 2.403 ENSMUST00000165909.1
Prom1
prominin 1
chr1_-_131097535 2.391 ENSMUST00000016672.4
Mapkapk2
MAP kinase-activated protein kinase 2
chr12_-_73113407 2.370 ENSMUST00000175693.1
Six4
sine oculis-related homeobox 4
chr18_-_47368446 2.369 ENSMUST00000076043.6
ENSMUST00000135790.1
Sema6a

sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6A

chr18_+_84088077 2.332 ENSMUST00000060223.2
Zadh2
zinc binding alcohol dehydrogenase, domain containing 2
chr15_+_100304782 2.306 ENSMUST00000067752.3
Mettl7a1
methyltransferase like 7A1
chr14_+_62292475 2.281 ENSMUST00000166879.1
Rnaseh2b
ribonuclease H2, subunit B
chr11_+_97029925 2.277 ENSMUST00000021249.4
Scrn2
secernin 2
chr14_+_47276910 2.258 ENSMUST00000065562.4
Socs4
suppressor of cytokine signaling 4
chr15_+_100353149 2.247 ENSMUST00000088142.5
ENSMUST00000176287.1
ENSMUST00000075675.5
Mettl7a2

AB099516
methyltransferase like 7A2

cDNA sequence AB099516
chr19_+_60144682 2.233 ENSMUST00000065383.4
E330013P04Rik
RIKEN cDNA E330013P04 gene
chr1_-_155232710 2.230 ENSMUST00000035914.3
BC034090
cDNA sequence BC034090
chr7_-_101837776 2.224 ENSMUST00000165052.1
Inppl1
inositol polyphosphate phosphatase-like 1
chr7_-_119895446 2.222 ENSMUST00000098080.2
Dcun1d3
DCN1, defective in cullin neddylation 1, domain containing 3 (S. cerevisiae)
chr2_-_122369130 2.213 ENSMUST00000151130.1
ENSMUST00000125826.1
Shf

Src homology 2 domain containing F

chr7_+_59228743 2.210 ENSMUST00000107537.1
Ube3a
ubiquitin protein ligase E3A
chr6_+_149408973 2.208 ENSMUST00000086829.4
ENSMUST00000111513.2
Bicd1

bicaudal D homolog 1 (Drosophila)

chr8_-_125492710 2.176 ENSMUST00000108775.1
Sipa1l2
signal-induced proliferation-associated 1 like 2
chr5_-_140389188 2.166 ENSMUST00000031539.7
Snx8
sorting nexin 8
chr1_+_172481788 2.162 ENSMUST00000127052.1
Igsf9
immunoglobulin superfamily, member 9
chr6_+_83135812 2.155 ENSMUST00000065512.4
Rtkn
rhotekin
chr7_+_134670667 2.155 ENSMUST00000084488.4
Dock1
dedicator of cytokinesis 1
chr2_+_83724397 2.132 ENSMUST00000028499.4
ENSMUST00000141725.1
ENSMUST00000111740.2
Itgav


integrin alpha V


chr9_-_16378231 2.112 ENSMUST00000082170.5
Fat3
FAT tumor suppressor homolog 3 (Drosophila)
chr7_+_29071597 2.094 ENSMUST00000180926.1
Gm26604
predicted gene, 26604
chr18_+_88971790 2.070 ENSMUST00000023828.7
Rttn
rotatin
chr2_+_38339258 2.065 ENSMUST00000143783.2
Lhx2
LIM homeobox protein 2
chr2_-_54085542 2.064 ENSMUST00000100089.2
Rprm
reprimo, TP53 dependent G2 arrest mediator candidate
chr5_+_115429585 2.042 ENSMUST00000150779.1
Msi1
musashi RNA-binding protein 1
chr2_+_155517948 2.042 ENSMUST00000029135.8
ENSMUST00000065973.2
ENSMUST00000103142.5
Acss2


acyl-CoA synthetase short-chain family member 2


chr10_+_50895651 2.023 ENSMUST00000020071.3
Sim1
single-minded homolog 1 (Drosophila)
chr17_-_70853482 2.003 ENSMUST00000118283.1
Tgif1
TGFB-induced factor homeobox 1
chrX_+_129749740 1.997 ENSMUST00000167619.2
ENSMUST00000037854.8
Diap2

diaphanous homolog 2 (Drosophila)

chr11_+_101316917 1.991 ENSMUST00000151385.1
Psme3
proteaseome (prosome, macropain) activator subunit 3 (PA28 gamma, Ki)
chr9_-_60141220 1.976 ENSMUST00000034829.5
Thsd4
thrombospondin, type I, domain containing 4
chr4_+_41762309 1.975 ENSMUST00000108042.2
Il11ra1
interleukin 11 receptor, alpha chain 1
chr8_-_87959560 1.970 ENSMUST00000109655.2
Zfp423
zinc finger protein 423
chrX_-_23285532 1.967 ENSMUST00000115319.2
Klhl13
kelch-like 13
chr14_+_55491062 1.967 ENSMUST00000076236.5
Lrrc16b
leucine rich repeat containing 16B
chr13_+_21722057 1.956 ENSMUST00000110476.3
Hist1h2bm
histone cluster 1, H2bm
chr18_+_64340225 1.926 ENSMUST00000175965.2
ENSMUST00000115145.3
Onecut2

one cut domain, family member 2

chr9_+_107578887 1.916 ENSMUST00000149638.1
ENSMUST00000139274.1
ENSMUST00000130053.1
ENSMUST00000122985.1
ENSMUST00000127380.1
ENSMUST00000139581.1
Nat6





N-acetyltransferase 6





chr9_+_14276301 1.913 ENSMUST00000034507.7
Sesn3
sestrin 3
chr2_-_60125651 1.912 ENSMUST00000112550.1
Baz2b
bromodomain adjacent to zinc finger domain, 2B
chr1_+_146420434 1.902 ENSMUST00000163646.1
Gm5263
predicted gene 5263
chr8_-_41041828 1.900 ENSMUST00000051379.7
Mtus1
mitochondrial tumor suppressor 1
chr17_+_31057686 1.886 ENSMUST00000024829.6
Abcg1
ATP-binding cassette, sub-family G (WHITE), member 1
chr10_+_73821857 1.871 ENSMUST00000177128.1
ENSMUST00000064562.7
ENSMUST00000129404.2
ENSMUST00000105426.3
ENSMUST00000131321.2
ENSMUST00000126920.2
ENSMUST00000147189.2
ENSMUST00000105424.3
ENSMUST00000092420.6
ENSMUST00000105429.3
ENSMUST00000131724.2
ENSMUST00000152655.2
ENSMUST00000151116.2
ENSMUST00000155701.2
ENSMUST00000152819.2
ENSMUST00000125517.2
ENSMUST00000124046.1
ENSMUST00000149977.2
ENSMUST00000146682.1
ENSMUST00000177107.1
Pcdh15



















protocadherin 15



















chr3_+_94377432 1.846 ENSMUST00000107292.1
Rorc
RAR-related orphan receptor gamma
chr11_+_113649328 1.842 ENSMUST00000063776.7
Cog1
component of oligomeric golgi complex 1
chr10_-_95324072 1.840 ENSMUST00000053594.5
Cradd
CASP2 and RIPK1 domain containing adaptor with death domain
chr9_+_27299205 1.835 ENSMUST00000115247.1
ENSMUST00000133213.1
Igsf9b

immunoglobulin superfamily, member 9B

chr11_+_101325063 1.832 ENSMUST00000041095.7
ENSMUST00000107264.1
Aoc2

amine oxidase, copper containing 2 (retina-specific)

chr3_+_96161981 1.825 ENSMUST00000054356.9
Mtmr11
myotubularin related protein 11
chr7_-_4515959 1.819 ENSMUST00000163710.1
ENSMUST00000166268.1
ENSMUST00000071798.6
ENSMUST00000178163.1
ENSMUST00000108587.2
Tnnt1




troponin T1, skeletal, slow




chr4_-_42168603 1.818 ENSMUST00000098121.3
Gm13305
predicted gene 13305
chr3_+_95232287 1.799 ENSMUST00000107200.1
ENSMUST00000107199.1
Cdc42se1

CDC42 small effector 1

chr7_+_101421691 1.793 ENSMUST00000163751.2
ENSMUST00000084894.7
ENSMUST00000166652.1
Pde2a


phosphodiesterase 2A, cGMP-stimulated


chr2_+_121295437 1.788 ENSMUST00000110639.1
Map1a
microtubule-associated protein 1 A

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
8.0 31.9 GO:0060032 notochord regression(GO:0060032)
4.3 21.5 GO:0015671 oxygen transport(GO:0015671)
4.2 29.4 GO:2001199 negative regulation of dendritic cell differentiation(GO:2001199)
3.0 14.9 GO:0030951 establishment or maintenance of microtubule cytoskeleton polarity(GO:0030951)
2.7 10.9 GO:0003365 establishment of cell polarity involved in ameboidal cell migration(GO:0003365)
2.6 7.7 GO:0001869 regulation of complement activation, lectin pathway(GO:0001868) negative regulation of complement activation, lectin pathway(GO:0001869)
2.2 8.8 GO:0070829 heterochromatin maintenance(GO:0070829)
2.1 23.4 GO:2000741 positive regulation of mesenchymal stem cell differentiation(GO:2000741)
2.0 12.3 GO:0021797 forebrain anterior/posterior pattern specification(GO:0021797)
2.0 6.0 GO:0060164 regulation of timing of neuron differentiation(GO:0060164)
1.9 9.7 GO:0007223 Wnt signaling pathway, calcium modulating pathway(GO:0007223)
1.3 4.0 GO:0006546 glycine catabolic process(GO:0006546) glycine decarboxylation via glycine cleavage system(GO:0019464)
1.3 9.2 GO:0031508 pericentric heterochromatin assembly(GO:0031508)
1.3 7.7 GO:0003383 apical constriction(GO:0003383)
1.3 8.9 GO:0043569 negative regulation of insulin-like growth factor receptor signaling pathway(GO:0043569)
1.2 2.5 GO:0002069 columnar/cuboidal epithelial cell maturation(GO:0002069)
1.2 3.6 GO:0044778 meiotic DNA integrity checkpoint(GO:0044778)
1.2 1.2 GO:0032916 positive regulation of transforming growth factor beta3 production(GO:0032916)
1.1 13.7 GO:2001269 positive regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway(GO:2001269)
1.1 6.7 GO:0071883 activation of MAPK activity by adrenergic receptor signaling pathway(GO:0071883)
1.1 3.3 GO:0006083 acetate metabolic process(GO:0006083)
1.0 11.4 GO:0060539 diaphragm development(GO:0060539)
0.9 2.7 GO:0072092 ureteric bud invasion(GO:0072092)
0.9 3.5 GO:2001045 closure of optic fissure(GO:0061386) negative regulation of integrin-mediated signaling pathway(GO:2001045)
0.9 2.6 GO:0034241 positive regulation of macrophage fusion(GO:0034241)
0.8 2.5 GO:0098528 skeletal muscle fiber differentiation(GO:0098528)
0.8 2.4 GO:0072139 glomerular parietal epithelial cell differentiation(GO:0072139)
0.8 3.9 GO:0042891 antibiotic transport(GO:0042891) dipeptide transport(GO:0042938)
0.8 3.1 GO:0007056 spindle assembly involved in female meiosis(GO:0007056)
0.8 10.6 GO:0007213 G-protein coupled acetylcholine receptor signaling pathway(GO:0007213)
0.7 3.0 GO:0042414 epinephrine metabolic process(GO:0042414)
0.7 2.2 GO:1900275 negative regulation of phospholipase C activity(GO:1900275)
0.7 2.1 GO:0038044 negative regulation of receptor biosynthetic process(GO:0010871) transforming growth factor-beta secretion(GO:0038044)
0.7 2.7 GO:1900220 semaphorin-plexin signaling pathway involved in bone trabecula morphogenesis(GO:1900220)
0.7 3.3 GO:0007089 traversing start control point of mitotic cell cycle(GO:0007089)
0.6 7.6 GO:0061302 smooth muscle cell-matrix adhesion(GO:0061302)
0.6 4.4 GO:1903715 regulation of aerobic respiration(GO:1903715)
0.6 9.3 GO:0048387 negative regulation of retinoic acid receptor signaling pathway(GO:0048387)
0.6 9.2 GO:0006085 acetyl-CoA biosynthetic process(GO:0006085)
0.6 1.8 GO:0033159 negative regulation of protein import into nucleus, translocation(GO:0033159)
0.6 1.8 GO:1900108 negative regulation of nodal signaling pathway(GO:1900108)
0.6 3.4 GO:0001842 neural fold formation(GO:0001842)
0.6 9.5 GO:0035563 positive regulation of chromatin binding(GO:0035563)
0.5 1.6 GO:0035574 histone H4-K20 demethylation(GO:0035574)
0.5 7.1 GO:0060013 righting reflex(GO:0060013)
0.5 1.5 GO:0043456 regulation of pentose-phosphate shunt(GO:0043456)
0.5 4.0 GO:0072615 interleukin-17 secretion(GO:0072615)
0.5 1.9 GO:0055099 response to high density lipoprotein particle(GO:0055099)
0.5 1.4 GO:0071211 protein targeting to vacuole involved in autophagy(GO:0071211)
0.5 3.2 GO:0048251 elastic fiber assembly(GO:0048251)
0.5 1.4 GO:1904058 positive regulation of sensory perception of pain(GO:1904058)
0.4 3.1 GO:0035188 blastocyst hatching(GO:0001835) hatching(GO:0035188) organism emergence from protective structure(GO:0071684)
0.4 1.3 GO:0044028 DNA hypomethylation(GO:0044028) hypomethylation of CpG island(GO:0044029)
0.4 2.9 GO:0031536 positive regulation of exit from mitosis(GO:0031536)
0.4 4.5 GO:0014883 transition between fast and slow fiber(GO:0014883)
0.4 1.7 GO:2001274 negative regulation of glucose import in response to insulin stimulus(GO:2001274)
0.4 2.4 GO:0044351 macropinocytosis(GO:0044351)
0.4 3.2 GO:0048102 autophagic cell death(GO:0048102)
0.4 3.9 GO:0002536 respiratory burst involved in inflammatory response(GO:0002536)
0.4 1.2 GO:0030327 prenylated protein catabolic process(GO:0030327)
0.4 0.8 GO:0051131 chaperone-mediated protein complex assembly(GO:0051131)
0.4 2.7 GO:0043568 positive regulation of insulin-like growth factor receptor signaling pathway(GO:0043568)
0.4 2.7 GO:1904217 regulation of CDP-diacylglycerol-serine O-phosphatidyltransferase activity(GO:1904217) positive regulation of CDP-diacylglycerol-serine O-phosphatidyltransferase activity(GO:1904219) regulation of serine C-palmitoyltransferase activity(GO:1904220) positive regulation of serine C-palmitoyltransferase activity(GO:1904222)
0.4 1.5 GO:1903998 regulation of eating behavior(GO:1903998)
0.4 3.8 GO:0051256 mitotic spindle midzone assembly(GO:0051256)
0.4 1.5 GO:0030860 regulation of polarized epithelial cell differentiation(GO:0030860)
0.4 3.4 GO:1900194 negative regulation of oocyte maturation(GO:1900194)
0.4 2.2 GO:0000160 phosphorelay signal transduction system(GO:0000160)
0.4 0.4 GO:0044333 Wnt signaling pathway involved in digestive tract morphogenesis(GO:0044333)
0.4 3.2 GO:0006104 succinyl-CoA metabolic process(GO:0006104)
0.4 1.1 GO:0002014 vasoconstriction of artery involved in ischemic response to lowering of systemic arterial blood pressure(GO:0002014)
0.4 3.2 GO:0036123 histone H3-K9 dimethylation(GO:0036123)
0.3 2.4 GO:0045198 establishment of epithelial cell apical/basal polarity(GO:0045198)
0.3 2.8 GO:0071802 negative regulation of podosome assembly(GO:0071802)
0.3 0.7 GO:0036075 endochondral ossification(GO:0001958) replacement ossification(GO:0036075)
0.3 1.0 GO:0035523 protein K29-linked deubiquitination(GO:0035523) protein K6-linked deubiquitination(GO:0044313)
0.3 2.7 GO:1903847 regulation of aorta morphogenesis(GO:1903847) positive regulation of aorta morphogenesis(GO:1903849)
0.3 1.0 GO:0070650 actin filament bundle distribution(GO:0070650)
0.3 1.3 GO:0046552 eye photoreceptor cell fate commitment(GO:0042706) photoreceptor cell fate commitment(GO:0046552)
0.3 1.6 GO:0046533 negative regulation of photoreceptor cell differentiation(GO:0046533) regulation of retinal cell programmed cell death(GO:0046668)
0.3 0.6 GO:0048386 positive regulation of retinoic acid receptor signaling pathway(GO:0048386)
0.3 1.3 GO:0051643 endoplasmic reticulum localization(GO:0051643)
0.3 5.3 GO:0071803 positive regulation of podosome assembly(GO:0071803)
0.3 0.9 GO:0090204 protein localization to nuclear pore(GO:0090204) negative regulation of vascular endothelial growth factor production(GO:1904046)
0.3 0.6 GO:0042713 sperm ejaculation(GO:0042713)
0.3 1.2 GO:0060011 Sertoli cell proliferation(GO:0060011)
0.3 8.3 GO:0007617 mating behavior(GO:0007617) multi-organism reproductive behavior(GO:0044705)
0.3 14.1 GO:0003301 physiological muscle hypertrophy(GO:0003298) physiological cardiac muscle hypertrophy(GO:0003301) cell growth involved in cardiac muscle cell development(GO:0061049)
0.3 0.3 GO:1904760 myofibroblast differentiation(GO:0036446) regulation of myofibroblast differentiation(GO:1904760)
0.3 0.9 GO:0036233 glycine import(GO:0036233)
0.3 0.9 GO:0048162 preantral ovarian follicle growth(GO:0001546) multi-layer follicle stage(GO:0048162)
0.3 8.7 GO:0032467 positive regulation of cytokinesis(GO:0032467)
0.3 0.9 GO:0019405 alditol catabolic process(GO:0019405)
0.3 0.9 GO:2000484 positive regulation of interleukin-8 secretion(GO:2000484)
0.3 2.8 GO:0090209 negative regulation of triglyceride metabolic process(GO:0090209)
0.3 1.4 GO:0014816 skeletal muscle satellite cell differentiation(GO:0014816)
0.3 5.0 GO:0007175 negative regulation of epidermal growth factor-activated receptor activity(GO:0007175)
0.3 1.1 GO:0072383 plus-end-directed vesicle transport along microtubule(GO:0072383) plus-end-directed organelle transport along microtubule(GO:0072386)
0.3 1.6 GO:0038031 non-canonical Wnt signaling pathway via JNK cascade(GO:0038031)
0.3 0.8 GO:0010838 positive regulation of keratinocyte proliferation(GO:0010838)
0.3 2.1 GO:0070317 negative regulation of G0 to G1 transition(GO:0070317)
0.3 1.5 GO:0007276 gamete generation(GO:0007276)
0.3 0.8 GO:0001880 Mullerian duct regression(GO:0001880)
0.3 0.8 GO:0070315 G1 to G0 transition involved in cell differentiation(GO:0070315)
0.3 1.3 GO:0035616 histone H2B conserved C-terminal lysine deubiquitination(GO:0035616)
0.2 2.2 GO:0060736 prostate gland growth(GO:0060736)
0.2 1.7 GO:0021830 interneuron migration from the subpallium to the cortex(GO:0021830)
0.2 3.8 GO:0048368 lateral mesoderm development(GO:0048368)
0.2 0.7 GO:0019046 release from viral latency(GO:0019046)
0.2 0.9 GO:0072385 minus-end-directed organelle transport along microtubule(GO:0072385)
0.2 1.6 GO:1901029 negative regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway(GO:1901029)
0.2 1.4 GO:0098964 dendritic transport of ribonucleoprotein complex(GO:0098961) dendritic transport of messenger ribonucleoprotein complex(GO:0098963) anterograde dendritic transport of messenger ribonucleoprotein complex(GO:0098964)
0.2 2.5 GO:0070986 left/right axis specification(GO:0070986)
0.2 1.5 GO:2000124 regulation of endocannabinoid signaling pathway(GO:2000124)
0.2 3.9 GO:0051450 myoblast proliferation(GO:0051450)
0.2 1.1 GO:1990839 response to endothelin(GO:1990839)
0.2 0.9 GO:0002175 protein localization to paranode region of axon(GO:0002175)
0.2 0.4 GO:1902065 response to L-glutamate(GO:1902065)
0.2 1.5 GO:0089700 protein kinase D signaling(GO:0089700)
0.2 6.5 GO:0034723 DNA replication-dependent nucleosome assembly(GO:0006335) DNA replication-dependent nucleosome organization(GO:0034723)
0.2 0.6 GO:1990927 negative regulation of tumor necrosis factor secretion(GO:1904468) negative regulation of membrane invagination(GO:1905154) calcium ion regulated lysosome exocytosis(GO:1990927)
0.2 1.2 GO:0051461 regulation of corticotropin secretion(GO:0051459) positive regulation of corticotropin secretion(GO:0051461)
0.2 0.4 GO:0035811 negative regulation of urine volume(GO:0035811)
0.2 1.2 GO:0042866 pyruvate biosynthetic process(GO:0042866)
0.2 0.6 GO:0002265 astrocyte activation involved in immune response(GO:0002265)
0.2 1.9 GO:0048934 peripheral nervous system neuron differentiation(GO:0048934) peripheral nervous system neuron development(GO:0048935)
0.2 0.6 GO:2000373 regulation of DNA topoisomerase (ATP-hydrolyzing) activity(GO:2000371) positive regulation of DNA topoisomerase (ATP-hydrolyzing) activity(GO:2000373)
0.2 0.9 GO:0071894 histone H2B conserved C-terminal lysine ubiquitination(GO:0071894)
0.2 1.5 GO:0072224 metanephric glomerulus development(GO:0072224)
0.2 0.9 GO:0051661 maintenance of centrosome location(GO:0051661)
0.2 0.4 GO:0060741 prostate gland stromal morphogenesis(GO:0060741)
0.2 0.4 GO:1904879 positive regulation of calcium ion transmembrane transport via high voltage-gated calcium channel(GO:1904879)
0.2 0.9 GO:0021631 optic nerve morphogenesis(GO:0021631)
0.2 0.9 GO:0030643 cellular phosphate ion homeostasis(GO:0030643) cellular trivalent inorganic anion homeostasis(GO:0072502)
0.2 0.5 GO:0090425 hepatocyte cell migration(GO:0002194) pancreas morphogenesis(GO:0061113) branching involved in pancreas morphogenesis(GO:0061114) acinar cell differentiation(GO:0090425) positive regulation of forebrain neuron differentiation(GO:2000979)
0.2 0.9 GO:2001168 regulation of histone H2B ubiquitination(GO:2001166) positive regulation of histone H2B ubiquitination(GO:2001168)
0.2 0.5 GO:1904211 membrane protein proteolysis involved in retrograde protein transport, ER to cytosol(GO:1904211)
0.2 0.5 GO:0019230 proprioception(GO:0019230)
0.2 1.6 GO:0007221 positive regulation of transcription of Notch receptor target(GO:0007221)
0.2 1.1 GO:0070345 negative regulation of fat cell proliferation(GO:0070345)
0.2 0.5 GO:0016056 photoreceptor cell morphogenesis(GO:0008594) rhodopsin mediated signaling pathway(GO:0016056) post-embryonic retina morphogenesis in camera-type eye(GO:0060060)
0.2 0.5 GO:2000642 negative regulation of early endosome to late endosome transport(GO:2000642)
0.2 0.9 GO:0035864 response to potassium ion(GO:0035864) cellular response to potassium ion(GO:0035865)
0.2 1.2 GO:0010571 positive regulation of nuclear cell cycle DNA replication(GO:0010571)
0.2 0.8 GO:0003420 regulation of growth plate cartilage chondrocyte proliferation(GO:0003420)
0.2 2.9 GO:0010225 response to UV-C(GO:0010225)
0.2 0.5 GO:0097350 neutrophil clearance(GO:0097350)
0.2 1.7 GO:0060689 cell differentiation involved in salivary gland development(GO:0060689)
0.2 0.7 GO:2000211 regulation of glutamate metabolic process(GO:2000211)
0.2 1.3 GO:1990845 adaptive thermogenesis(GO:1990845)
0.2 0.2 GO:0071921 establishment of sister chromatid cohesion(GO:0034085) cohesin loading(GO:0071921) regulation of cohesin loading(GO:0071922)
0.2 0.6 GO:0072272 proximal/distal pattern formation involved in metanephric nephron development(GO:0072272)
0.2 0.6 GO:1902224 cellular ketone body metabolic process(GO:0046950) ketone body metabolic process(GO:1902224)
0.2 2.4 GO:2001224 positive regulation of neuron migration(GO:2001224)
0.2 5.2 GO:0007026 negative regulation of microtubule depolymerization(GO:0007026)
0.2 1.6 GO:0006977 DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest(GO:0006977)
0.2 1.1 GO:0003263 cardioblast proliferation(GO:0003263) regulation of cardioblast proliferation(GO:0003264)
0.2 2.7 GO:0045671 negative regulation of osteoclast differentiation(GO:0045671)
0.1 1.2 GO:1902730 positive regulation of proteoglycan biosynthetic process(GO:1902730)
0.1 0.7 GO:0060124 positive regulation of growth hormone secretion(GO:0060124)
0.1 0.6 GO:0090298 mitochondrial DNA repair(GO:0043504) negative regulation of mitochondrial DNA replication(GO:0090298)
0.1 1.6 GO:0034498 early endosome to Golgi transport(GO:0034498)
0.1 1.3 GO:0038203 TORC2 signaling(GO:0038203)
0.1 1.1 GO:0090205 positive regulation of cholesterol biosynthetic process(GO:0045542) positive regulation of cholesterol metabolic process(GO:0090205)
0.1 0.6 GO:0070537 histone H2A K63-linked deubiquitination(GO:0070537)
0.1 0.4 GO:1903630 regulation of aminoacyl-tRNA ligase activity(GO:1903630) positive regulation of aminoacyl-tRNA ligase activity(GO:1903632) regulation of protein neddylation(GO:2000434) negative regulation of protein neddylation(GO:2000435)
0.1 0.7 GO:0018242 protein O-linked glycosylation via serine(GO:0018242)
0.1 3.4 GO:0048026 positive regulation of mRNA splicing, via spliceosome(GO:0048026)
0.1 1.0 GO:0002002 regulation of angiotensin levels in blood(GO:0002002)
0.1 0.8 GO:0090160 Golgi to lysosome transport(GO:0090160)
0.1 0.4 GO:0016598 protein arginylation(GO:0016598)
0.1 1.3 GO:0034242 negative regulation of syncytium formation by plasma membrane fusion(GO:0034242)
0.1 1.6 GO:0021521 ventral spinal cord interneuron specification(GO:0021521) cell fate specification involved in pattern specification(GO:0060573)
0.1 0.4 GO:0006582 melanin metabolic process(GO:0006582) melanin biosynthetic process(GO:0042438) secondary metabolite biosynthetic process(GO:0044550)
0.1 0.3 GO:0060971 embryonic heart tube left/right pattern formation(GO:0060971)
0.1 1.0 GO:0051289 protein homotetramerization(GO:0051289)
0.1 1.9 GO:0045579 positive regulation of B cell differentiation(GO:0045579)
0.1 2.0 GO:0001833 inner cell mass cell proliferation(GO:0001833)
0.1 2.7 GO:0033120 positive regulation of RNA splicing(GO:0033120)
0.1 0.5 GO:0014012 peripheral nervous system axon regeneration(GO:0014012)
0.1 0.1 GO:0045006 U4 snRNA 3'-end processing(GO:0034475) DNA deamination(GO:0045006) polyadenylation-dependent snoRNA 3'-end processing(GO:0071051)
0.1 0.7 GO:0097473 cellular response to light intensity(GO:0071484) cellular response to high light intensity(GO:0071486) retinal rod cell apoptotic process(GO:0097473)
0.1 0.5 GO:0060800 regulation of cell differentiation involved in embryonic placenta development(GO:0060800)
0.1 1.4 GO:0000083 regulation of transcription involved in G1/S transition of mitotic cell cycle(GO:0000083)
0.1 1.0 GO:0033148 positive regulation of intracellular estrogen receptor signaling pathway(GO:0033148)
0.1 1.3 GO:0097151 positive regulation of inhibitory postsynaptic potential(GO:0097151)
0.1 0.6 GO:0050908 detection of light stimulus involved in visual perception(GO:0050908) detection of light stimulus involved in sensory perception(GO:0050962)
0.1 9.7 GO:0043488 regulation of mRNA stability(GO:0043488)
0.1 1.2 GO:0018065 protein-cofactor linkage(GO:0018065)
0.1 0.6 GO:0035873 lactate transport(GO:0015727) lactate transmembrane transport(GO:0035873) plasma membrane lactate transport(GO:0035879)
0.1 3.1 GO:0002053 positive regulation of mesenchymal cell proliferation(GO:0002053)
0.1 2.1 GO:2000001 regulation of DNA damage checkpoint(GO:2000001)
0.1 3.3 GO:1902807 negative regulation of cell cycle G1/S phase transition(GO:1902807)
0.1 1.6 GO:0014742 positive regulation of cardiac muscle hypertrophy(GO:0010613) positive regulation of muscle hypertrophy(GO:0014742)
0.1 0.8 GO:0032074 negative regulation of nuclease activity(GO:0032074)
0.1 0.7 GO:0070863 positive regulation of protein exit from endoplasmic reticulum(GO:0070863)
0.1 2.1 GO:2000678 negative regulation of transcription regulatory region DNA binding(GO:2000678)
0.1 1.2 GO:0002227 innate immune response in mucosa(GO:0002227)
0.1 0.6 GO:1904715 negative regulation of chaperone-mediated autophagy(GO:1904715)
0.1 0.3 GO:1903225 negative regulation of endodermal cell differentiation(GO:1903225)
0.1 2.1 GO:0035036 binding of sperm to zona pellucida(GO:0007339) sperm-egg recognition(GO:0035036)
0.1 0.3 GO:0061009 common bile duct development(GO:0061009)
0.1 0.4 GO:0032289 central nervous system myelin formation(GO:0032289) cardiac cell fate specification(GO:0060912)
0.1 0.7 GO:0048096 chromatin-mediated maintenance of transcription(GO:0048096)
0.1 0.3 GO:0046340 diacylglycerol catabolic process(GO:0046340)
0.1 0.7 GO:0051967 negative regulation of synaptic transmission, glutamatergic(GO:0051967)
0.1 0.1 GO:0051255 spindle midzone assembly(GO:0051255)
0.1 0.5 GO:2000254 regulation of male germ cell proliferation(GO:2000254)
0.1 0.6 GO:0030263 apoptotic chromosome condensation(GO:0030263)
0.1 0.2 GO:0036151 phosphatidylcholine acyl-chain remodeling(GO:0036151)
0.1 0.3 GO:0042135 neurotransmitter catabolic process(GO:0042135)
0.1 0.6 GO:0098703 calcium ion import across plasma membrane(GO:0098703) calcium ion import into cell(GO:1990035)
0.1 1.3 GO:0035721 intraciliary retrograde transport(GO:0035721)
0.1 0.3 GO:0014874 response to stimulus involved in regulation of muscle adaptation(GO:0014874)
0.1 2.2 GO:0010842 retina layer formation(GO:0010842)
0.1 1.5 GO:0060218 hematopoietic stem cell differentiation(GO:0060218)
0.1 2.4 GO:0010569 regulation of double-strand break repair via homologous recombination(GO:0010569)
0.1 0.3 GO:0006526 arginine biosynthetic process(GO:0006526)
0.1 0.5 GO:0090315 negative regulation of protein targeting to membrane(GO:0090315)
0.1 0.2 GO:0033762 response to glucagon(GO:0033762)
0.1 1.1 GO:0046697 decidualization(GO:0046697)
0.1 0.2 GO:1902396 protein localization to bicellular tight junction(GO:1902396)
0.1 0.4 GO:0071361 cellular response to ethanol(GO:0071361)
0.1 0.4 GO:0032329 serine transport(GO:0032329)
0.1 0.9 GO:0043046 DNA methylation involved in gamete generation(GO:0043046)
0.1 5.7 GO:0043525 positive regulation of neuron apoptotic process(GO:0043525)
0.1 0.5 GO:0018344 protein geranylgeranylation(GO:0018344)
0.1 1.9 GO:0010758 regulation of macrophage chemotaxis(GO:0010758)
0.1 1.3 GO:0071786 endoplasmic reticulum tubular network organization(GO:0071786)
0.1 0.5 GO:0045721 negative regulation of gluconeogenesis(GO:0045721)
0.1 0.4 GO:0006004 fucose metabolic process(GO:0006004)
0.1 0.6 GO:0051353 positive regulation of oxidoreductase activity(GO:0051353)
0.1 0.1 GO:2000157 regulation of protein K48-linked deubiquitination(GO:1903093) negative regulation of protein K48-linked deubiquitination(GO:1903094) negative regulation of ubiquitin-specific protease activity(GO:2000157)
0.1 1.3 GO:0007050 cell cycle arrest(GO:0007050)
0.1 0.1 GO:2000646 positive regulation of receptor catabolic process(GO:2000646)
0.1 0.4 GO:1902715 positive regulation of interferon-gamma secretion(GO:1902715)
0.1 2.6 GO:0000460 maturation of 5.8S rRNA(GO:0000460)
0.1 0.5 GO:0043247 protection from non-homologous end joining at telomere(GO:0031848) telomere maintenance in response to DNA damage(GO:0043247)
0.1 0.6 GO:0032366 intracellular sterol transport(GO:0032366) intracellular cholesterol transport(GO:0032367)
0.1 0.3 GO:0050912 detection of chemical stimulus involved in sensory perception(GO:0050907) detection of chemical stimulus involved in sensory perception of taste(GO:0050912)
0.1 2.3 GO:0031648 protein destabilization(GO:0031648)
0.1 0.5 GO:0035331 negative regulation of hippo signaling(GO:0035331)
0.1 0.2 GO:0045759 negative regulation of action potential(GO:0045759)
0.1 0.6 GO:0014029 neural crest formation(GO:0014029)
0.1 1.3 GO:0000132 establishment of mitotic spindle orientation(GO:0000132)
0.1 0.4 GO:0097428 protein maturation by iron-sulfur cluster transfer(GO:0097428)
0.1 0.4 GO:1990403 embryonic brain development(GO:1990403)
0.1 1.4 GO:1902857 positive regulation of nonmotile primary cilium assembly(GO:1902857)
0.1 0.8 GO:0043374 CD8-positive, alpha-beta T cell differentiation(GO:0043374)
0.1 2.3 GO:0000184 nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:0000184)
0.1 0.5 GO:0045899 positive regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0045899)
0.1 0.4 GO:0061368 behavioral response to chemical pain(GO:0061366) behavioral response to formalin induced pain(GO:0061368) modification of postsynaptic actin cytoskeleton(GO:0098885)
0.1 4.5 GO:0072332 intrinsic apoptotic signaling pathway by p53 class mediator(GO:0072332)
0.1 1.1 GO:0014046 dopamine secretion(GO:0014046) regulation of dopamine secretion(GO:0014059)
0.1 0.3 GO:0001672 regulation of chromatin assembly or disassembly(GO:0001672)
0.1 0.4 GO:0046322 negative regulation of fatty acid oxidation(GO:0046322)
0.1 0.5 GO:0023019 signal transduction involved in regulation of gene expression(GO:0023019)
0.1 1.8 GO:1900026 positive regulation of substrate adhesion-dependent cell spreading(GO:1900026)
0.1 0.6 GO:0046031 ADP metabolic process(GO:0046031)
0.1 0.4 GO:0010835 regulation of protein ADP-ribosylation(GO:0010835)
0.1 0.2 GO:2001271 negative regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:2001271)
0.1 1.1 GO:0006825 copper ion transport(GO:0006825)
0.1 0.6 GO:2001223 negative regulation of neuron migration(GO:2001223)
0.1 0.2 GO:0009414 response to water deprivation(GO:0009414)
0.1 0.1 GO:0031086 nuclear-transcribed mRNA catabolic process, deadenylation-independent decay(GO:0031086) deadenylation-independent decapping of nuclear-transcribed mRNA(GO:0031087)
0.1 1.4 GO:0007099 centriole replication(GO:0007099)
0.0 0.2 GO:0001812 positive regulation of type I hypersensitivity(GO:0001812)
0.0 0.7 GO:0045116 protein neddylation(GO:0045116)
0.0 1.8 GO:0009712 catecholamine metabolic process(GO:0006584) catechol-containing compound metabolic process(GO:0009712)
0.0 1.9 GO:0046329 negative regulation of JNK cascade(GO:0046329)
0.0 1.7 GO:0006891 intra-Golgi vesicle-mediated transport(GO:0006891)
0.0 0.5 GO:1903504 regulation of mitotic cell cycle spindle assembly checkpoint(GO:0090266) regulation of mitotic spindle checkpoint(GO:1903504)
0.0 0.5 GO:0051123 RNA polymerase II transcriptional preinitiation complex assembly(GO:0051123)
0.0 0.4 GO:0090073 positive regulation of protein homodimerization activity(GO:0090073)
0.0 0.3 GO:0090043 regulation of tubulin deacetylation(GO:0090043)
0.0 0.9 GO:0038083 peptidyl-tyrosine autophosphorylation(GO:0038083)
0.0 0.6 GO:0090110 cargo loading into COPII-coated vesicle(GO:0090110)
0.0 0.9 GO:0032967 positive regulation of collagen biosynthetic process(GO:0032967)
0.0 3.7 GO:0006342 chromatin silencing(GO:0006342)
0.0 0.1 GO:0061724 lipophagy(GO:0061724) regulation of lipophagy(GO:1904502) positive regulation of lipophagy(GO:1904504)
0.0 0.7 GO:0045947 negative regulation of translational initiation(GO:0045947)
0.0 0.5 GO:0006654 phosphatidic acid biosynthetic process(GO:0006654)
0.0 0.5 GO:1902187 negative regulation of viral release from host cell(GO:1902187)
0.0 0.6 GO:0046580 negative regulation of Ras protein signal transduction(GO:0046580) negative regulation of small GTPase mediated signal transduction(GO:0051058)
0.0 0.4 GO:0090385 phagosome-lysosome fusion(GO:0090385)
0.0 0.2 GO:0090370 negative regulation of cholesterol efflux(GO:0090370)
0.0 0.2 GO:2000096 regulation of Wnt signaling pathway, planar cell polarity pathway(GO:2000095) positive regulation of Wnt signaling pathway, planar cell polarity pathway(GO:2000096)
0.0 0.4 GO:0006013 mannose metabolic process(GO:0006013)
0.0 0.2 GO:0031547 brain-derived neurotrophic factor receptor signaling pathway(GO:0031547)
0.0 0.7 GO:0051016 barbed-end actin filament capping(GO:0051016)
0.0 0.5 GO:0048642 negative regulation of skeletal muscle tissue development(GO:0048642)
0.0 1.7 GO:0035383 acyl-CoA metabolic process(GO:0006637) thioester metabolic process(GO:0035383)
0.0 0.2 GO:0090200 positive regulation of release of cytochrome c from mitochondria(GO:0090200)
0.0 0.4 GO:0030728 ovulation(GO:0030728)
0.0 0.1 GO:0036515 serotonergic neuron axon guidance(GO:0036515)
0.0 0.2 GO:0052428 modulation of molecular function in other organism(GO:0044359) negative regulation of molecular function in other organism(GO:0044362) negative regulation of molecular function in other organism involved in symbiotic interaction(GO:0052204) modulation of molecular function in other organism involved in symbiotic interaction(GO:0052205) negative regulation by host of symbiont molecular function(GO:0052405) modification by host of symbiont molecular function(GO:0052428)
0.0 0.4 GO:0016601 Rac protein signal transduction(GO:0016601)
0.0 0.3 GO:0061635 regulation of protein complex stability(GO:0061635)
0.0 0.6 GO:0046827 positive regulation of protein export from nucleus(GO:0046827)
0.0 1.0 GO:0000381 regulation of alternative mRNA splicing, via spliceosome(GO:0000381)
0.0 0.3 GO:0003148 outflow tract septum morphogenesis(GO:0003148)
0.0 1.0 GO:0007608 sensory perception of smell(GO:0007608)
0.0 0.1 GO:0099527 postsynapse to nucleus signaling pathway(GO:0099527)
0.0 0.3 GO:0090132 epithelial cell migration(GO:0010631) tissue migration(GO:0090130) epithelium migration(GO:0090132)
0.0 5.0 GO:0008360 regulation of cell shape(GO:0008360)
0.0 0.1 GO:2001013 epithelial cell proliferation involved in renal tubule morphogenesis(GO:2001013)
0.0 1.7 GO:0006635 fatty acid beta-oxidation(GO:0006635)
0.0 0.3 GO:0061088 sequestering of zinc ion(GO:0032119) regulation of sequestering of zinc ion(GO:0061088)
0.0 0.3 GO:0031584 activation of phospholipase D activity(GO:0031584)
0.0 0.5 GO:0009409 response to cold(GO:0009409)
0.0 0.1 GO:0006384 transcription initiation from RNA polymerase III promoter(GO:0006384)
0.0 0.2 GO:2000507 positive regulation of energy homeostasis(GO:2000507)
0.0 0.8 GO:0000462 maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000462)
0.0 0.8 GO:0018345 protein palmitoylation(GO:0018345)
0.0 0.3 GO:0006662 glycerol ether metabolic process(GO:0006662) ether metabolic process(GO:0018904)
0.0 1.0 GO:0006911 phagocytosis, engulfment(GO:0006911)
0.0 0.2 GO:0045599 negative regulation of fat cell differentiation(GO:0045599)
0.0 0.3 GO:0030316 osteoclast differentiation(GO:0030316)
0.0 0.2 GO:0097067 mRNA transcription from RNA polymerase II promoter(GO:0042789) cellular response to thyroid hormone stimulus(GO:0097067)
0.0 0.1 GO:0006543 glutamine catabolic process(GO:0006543)
0.0 0.1 GO:1901724 positive regulation of cell proliferation involved in kidney development(GO:1901724)
0.0 0.3 GO:2000480 negative regulation of cAMP-dependent protein kinase activity(GO:2000480)
0.0 0.8 GO:0032728 positive regulation of interferon-beta production(GO:0032728)
0.0 0.1 GO:0043985 histone H4-R3 methylation(GO:0043985)
0.0 0.3 GO:0006620 posttranslational protein targeting to membrane(GO:0006620)
0.0 0.1 GO:0003417 growth plate cartilage development(GO:0003417)
0.0 0.3 GO:0048147 negative regulation of fibroblast proliferation(GO:0048147)
0.0 0.1 GO:2000491 positive regulation of hepatic stellate cell activation(GO:2000491)
0.0 0.7 GO:0006368 transcription elongation from RNA polymerase II promoter(GO:0006368)
0.0 0.2 GO:0035428 hexose transmembrane transport(GO:0035428)
0.0 0.7 GO:0045670 regulation of osteoclast differentiation(GO:0045670)
0.0 0.8 GO:0043044 ATP-dependent chromatin remodeling(GO:0043044)
0.0 0.3 GO:0099628 receptor diffusion trapping(GO:0098953) postsynaptic neurotransmitter receptor diffusion trapping(GO:0098970) neurotransmitter receptor diffusion trapping(GO:0099628)
0.0 0.1 GO:0090502 RNA phosphodiester bond hydrolysis, endonucleolytic(GO:0090502)
0.0 1.8 GO:0006413 translational initiation(GO:0006413)
0.0 0.2 GO:0006610 ribosomal protein import into nucleus(GO:0006610)
0.0 0.1 GO:0051388 positive regulation of neurotrophin TRK receptor signaling pathway(GO:0051388)
0.0 0.5 GO:0070979 protein K11-linked ubiquitination(GO:0070979)
0.0 0.3 GO:0061013 regulation of mRNA catabolic process(GO:0061013) positive regulation of mRNA catabolic process(GO:0061014)
0.0 0.4 GO:1900087 positive regulation of G1/S transition of mitotic cell cycle(GO:1900087)
0.0 0.2 GO:0061003 positive regulation of dendritic spine morphogenesis(GO:0061003)
0.0 0.4 GO:1901184 regulation of ERBB signaling pathway(GO:1901184)
0.0 0.3 GO:0097034 mitochondrial respiratory chain complex IV assembly(GO:0033617) mitochondrial respiratory chain complex IV biogenesis(GO:0097034)
0.0 0.6 GO:0007029 endoplasmic reticulum organization(GO:0007029)
0.0 1.1 GO:0080171 lysosome organization(GO:0007040) lytic vacuole organization(GO:0080171)
0.0 0.1 GO:0018125 peptidyl-cysteine methylation(GO:0018125)
0.0 0.3 GO:0006383 transcription from RNA polymerase III promoter(GO:0006383)
0.0 0.2 GO:0014065 phosphatidylinositol 3-kinase signaling(GO:0014065)
0.0 0.2 GO:0043984 histone H4-K16 acetylation(GO:0043984)
0.0 0.2 GO:0010667 negative regulation of cardiac muscle cell apoptotic process(GO:0010667)
0.0 0.1 GO:2000780 negative regulation of double-strand break repair(GO:2000780)
0.0 0.0 GO:1900186 negative regulation of clathrin-mediated endocytosis(GO:1900186)
0.0 0.3 GO:2001243 negative regulation of intrinsic apoptotic signaling pathway(GO:2001243)
0.0 0.0 GO:0071550 death-inducing signaling complex assembly(GO:0071550)
0.0 0.1 GO:0006924 activation-induced cell death of T cells(GO:0006924)
0.0 0.6 GO:0009953 dorsal/ventral pattern formation(GO:0009953)
0.0 0.0 GO:0097494 regulation of vesicle size(GO:0097494)
0.0 0.2 GO:1902043 positive regulation of extrinsic apoptotic signaling pathway via death domain receptors(GO:1902043)
0.0 0.1 GO:0016266 O-glycan processing(GO:0016266)
0.0 0.0 GO:0060850 regulation of transcription involved in cell fate commitment(GO:0060850)
0.0 0.4 GO:0008347 glial cell migration(GO:0008347)
0.0 0.2 GO:0045070 positive regulation of viral genome replication(GO:0045070)
0.0 0.2 GO:0002011 morphogenesis of an epithelial sheet(GO:0002011)
0.0 0.2 GO:0032355 response to estradiol(GO:0032355)
0.0 0.2 GO:0006301 postreplication repair(GO:0006301)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
2.5 32.1 GO:0097542 ciliary tip(GO:0097542)
1.8 14.4 GO:0005833 hemoglobin complex(GO:0005833)
1.3 3.8 GO:0071149 TEAD-2-YAP complex(GO:0071149)
1.2 6.1 GO:0032133 chromosome passenger complex(GO:0032133)
1.1 3.2 GO:0071148 TEAD-1-YAP complex(GO:0071148)
1.0 3.0 GO:0045009 melanosome membrane(GO:0033162) chitosome(GO:0045009)
0.9 3.4 GO:0090537 CERF complex(GO:0090537)
0.8 6.7 GO:0033269 internode region of axon(GO:0033269)
0.8 2.4 GO:0071914 prominosome(GO:0071914)
0.8 3.9 GO:0031523 Myb complex(GO:0031523)
0.7 2.1 GO:0034684 integrin alphav-beta5 complex(GO:0034684)
0.6 1.8 GO:0044302 dentate gyrus mossy fiber(GO:0044302)
0.5 1.6 GO:0097058 CRLF-CLCF1 complex(GO:0097058)
0.5 2.0 GO:0008537 proteasome activator complex(GO:0008537)
0.5 2.9 GO:0030896 checkpoint clamp complex(GO:0030896)
0.5 2.8 GO:0032299 ribonuclease H2 complex(GO:0032299)
0.5 1.4 GO:0031088 platelet dense granule membrane(GO:0031088) intrinsic component of autophagosome membrane(GO:0097636) integral component of autophagosome membrane(GO:0097637)
0.5 7.0 GO:0042788 polysomal ribosome(GO:0042788)
0.4 2.2 GO:0033648 host intracellular organelle(GO:0033647) host intracellular membrane-bounded organelle(GO:0033648)
0.4 1.3 GO:0005943 phosphatidylinositol 3-kinase complex, class IA(GO:0005943)
0.4 1.3 GO:0042642 actomyosin, myosin complex part(GO:0042642)
0.4 13.3 GO:0035371 microtubule plus-end(GO:0035371)
0.4 1.5 GO:0089717 spanning component of plasma membrane(GO:0044214) spanning component of membrane(GO:0089717)
0.4 8.5 GO:0030285 integral component of synaptic vesicle membrane(GO:0030285) intrinsic component of synaptic vesicle membrane(GO:0098563)
0.3 3.4 GO:0010369 chromocenter(GO:0010369)
0.3 1.3 GO:0044352 pinosome(GO:0044352) macropinosome(GO:0044354)
0.3 4.3 GO:0032045 guanyl-nucleotide exchange factor complex(GO:0032045)
0.3 1.2 GO:0017071 intracellular cyclic nucleotide activated cation channel complex(GO:0017071)
0.3 9.2 GO:0005721 pericentric heterochromatin(GO:0005721)
0.3 1.7 GO:0005726 perichromatin fibrils(GO:0005726)
0.3 0.6 GO:0070971 endoplasmic reticulum exit site(GO:0070971)
0.3 1.4 GO:0005861 troponin complex(GO:0005861)
0.3 2.7 GO:0016600 flotillin complex(GO:0016600)
0.3 1.0 GO:1990032 parallel fiber(GO:1990032)
0.3 1.3 GO:0072487 MSL complex(GO:0072487)
0.2 1.0 GO:0042105 alpha-beta T cell receptor complex(GO:0042105)
0.2 3.2 GO:0043205 microfibril(GO:0001527) fibril(GO:0043205)
0.2 1.5 GO:0043256 laminin complex(GO:0043256)
0.2 7.4 GO:0072562 blood microparticle(GO:0072562)
0.2 5.3 GO:0060077 inhibitory synapse(GO:0060077)
0.2 11.0 GO:0008180 COP9 signalosome(GO:0008180)
0.2 0.7 GO:0043224 nuclear SCF ubiquitin ligase complex(GO:0043224)
0.2 0.9 GO:0000235 astral microtubule(GO:0000235)
0.2 2.2 GO:0070545 PeBoW complex(GO:0070545)
0.2 3.8 GO:0016010 dystrophin-associated glycoprotein complex(GO:0016010) glycoprotein complex(GO:0090665)
0.2 1.3 GO:0031105 septin complex(GO:0031105) septin cytoskeleton(GO:0032156)
0.2 1.1 GO:0005968 Rab-protein geranylgeranyltransferase complex(GO:0005968)
0.2 0.9 GO:0097454 Schwann cell microvillus(GO:0097454)
0.2 1.0 GO:0097513 myosin II filament(GO:0097513)
0.2 1.6 GO:0000127 transcription factor TFIIIC complex(GO:0000127)
0.2 1.1 GO:0030062 mitochondrial tricarboxylic acid cycle enzyme complex(GO:0030062)
0.2 1.1 GO:0071817 MMXD complex(GO:0071817)
0.2 7.8 GO:0002102 podosome(GO:0002102)
0.2 2.4 GO:0035686 sperm fibrous sheath(GO:0035686)
0.2 9.4 GO:0005871 kinesin complex(GO:0005871)
0.2 1.4 GO:0002177 manchette(GO:0002177)
0.2 1.4 GO:0097442 CA3 pyramidal cell dendrite(GO:0097442)
0.2 0.9 GO:0032983 kainate selective glutamate receptor complex(GO:0032983)
0.2 5.0 GO:0000788 nuclear nucleosome(GO:0000788)
0.1 0.6 GO:0070552 BRISC complex(GO:0070552)
0.1 1.3 GO:0030991 intraciliary transport particle A(GO:0030991)
0.1 5.2 GO:0000786 nucleosome(GO:0000786)
0.1 0.6 GO:1902937 inward rectifier potassium channel complex(GO:1902937)
0.1 1.7 GO:0034663 endoplasmic reticulum chaperone complex(GO:0034663)
0.1 1.4 GO:0030130 clathrin coat of trans-Golgi network vesicle(GO:0030130)
0.1 5.0 GO:0032809 neuronal cell body membrane(GO:0032809)
0.1 0.5 GO:0030289 protein phosphatase 4 complex(GO:0030289)
0.1 0.9 GO:0033503 HULC complex(GO:0033503)
0.1 1.8 GO:0000974 Prp19 complex(GO:0000974)
0.1 13.1 GO:0032993 protein-DNA complex(GO:0032993)
0.1 1.6 GO:0031597 cytosolic proteasome complex(GO:0031597)
0.1 5.7 GO:0097610 cleavage furrow(GO:0032154) cell surface furrow(GO:0097610)
0.1 0.9 GO:0044613 nuclear pore central transport channel(GO:0044613)
0.1 1.2 GO:0097136 Bcl-2 family protein complex(GO:0097136)
0.1 0.6 GO:0070937 CRD-mediated mRNA stability complex(GO:0070937)
0.1 0.4 GO:0030132 clathrin coat of coated pit(GO:0030132)
0.1 0.9 GO:0005642 annulate lamellae(GO:0005642)
0.1 0.2 GO:1990812 growth cone filopodium(GO:1990812)
0.1 0.7 GO:0033588 Elongator holoenzyme complex(GO:0033588)
0.1 0.7 GO:0071203 WASH complex(GO:0071203)
0.1 0.3 GO:0005588 collagen type V trimer(GO:0005588)
0.1 0.9 GO:0031235 intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235)
0.1 0.6 GO:0097422 tubular endosome(GO:0097422)
0.1 0.1 GO:0005940 septin ring(GO:0005940)
0.1 0.4 GO:0001891 phagocytic cup(GO:0001891)
0.1 1.0 GO:0061700 GATOR2 complex(GO:0061700)
0.1 0.7 GO:0048188 Set1C/COMPASS complex(GO:0048188)
0.1 1.2 GO:0097539 ciliary transition fiber(GO:0097539)
0.1 3.1 GO:0016592 mediator complex(GO:0016592)
0.1 1.1 GO:0017119 Golgi transport complex(GO:0017119)
0.1 0.5 GO:0030496 midbody(GO:0030496)
0.1 6.0 GO:0005913 cell-cell adherens junction(GO:0005913)
0.1 0.6 GO:0061574 ASAP complex(GO:0061574)
0.1 0.5 GO:0070419 nonhomologous end joining complex(GO:0070419)
0.1 0.5 GO:0042824 MHC class I peptide loading complex(GO:0042824)
0.1 0.8 GO:0044666 MLL3/4 complex(GO:0044666)
0.1 24.7 GO:0005667 transcription factor complex(GO:0005667)
0.1 1.5 GO:0005682 U5 snRNP(GO:0005682)
0.1 1.1 GO:0005640 nuclear outer membrane(GO:0005640)
0.1 0.4 GO:0034098 VCP-NPL4-UFD1 AAA ATPase complex(GO:0034098)
0.1 3.4 GO:0005811 lipid particle(GO:0005811)
0.1 0.6 GO:0000015 phosphopyruvate hydratase complex(GO:0000015)
0.1 0.6 GO:0032009 early phagosome(GO:0032009)
0.1 0.4 GO:0031143 pseudopodium(GO:0031143)
0.1 0.1 GO:0031595 nuclear proteasome complex(GO:0031595)
0.1 0.7 GO:0032593 insulin-responsive compartment(GO:0032593)
0.1 2.9 GO:0016459 myosin complex(GO:0016459)
0.1 4.6 GO:0030136 clathrin-coated vesicle(GO:0030136)
0.1 1.0 GO:0030904 retromer complex(GO:0030904)
0.1 0.4 GO:0005851 eukaryotic translation initiation factor 2B complex(GO:0005851)
0.1 2.0 GO:0034707 chloride channel complex(GO:0034707)
0.1 0.1 GO:0031209 SCAR complex(GO:0031209)
0.0 0.3 GO:0005964 phosphorylase kinase complex(GO:0005964)
0.0 0.7 GO:0005858 axonemal dynein complex(GO:0005858)
0.0 0.7 GO:0036513 Derlin-1 retrotranslocation complex(GO:0036513)
0.0 1.6 GO:0005637 nuclear inner membrane(GO:0005637)
0.0 0.5 GO:0045171 intercellular bridge(GO:0045171)
0.0 0.8 GO:0005868 cytoplasmic dynein complex(GO:0005868)
0.0 0.7 GO:0071564 npBAF complex(GO:0071564)
0.0 0.4 GO:0033180 proton-transporting V-type ATPase, V1 domain(GO:0033180)
0.0 0.5 GO:0042571 immunoglobulin complex, circulating(GO:0042571)
0.0 0.4 GO:1990454 L-type voltage-gated calcium channel complex(GO:1990454)
0.0 2.1 GO:0001750 photoreceptor outer segment(GO:0001750)
0.0 0.6 GO:0043196 varicosity(GO:0043196)
0.0 0.3 GO:0005787 signal peptidase complex(GO:0005787)
0.0 0.2 GO:0031673 H zone(GO:0031673)
0.0 0.2 GO:0044308 axonal spine(GO:0044308)
0.0 0.4 GO:0000940 condensed chromosome outer kinetochore(GO:0000940)
0.0 0.7 GO:0016581 NuRD complex(GO:0016581) CHD-type complex(GO:0090545)
0.0 0.9 GO:0005903 brush border(GO:0005903)
0.0 0.4 GO:0043240 Fanconi anaemia nuclear complex(GO:0043240)
0.0 0.8 GO:0000795 synaptonemal complex(GO:0000795)
0.0 0.4 GO:0031011 Ino80 complex(GO:0031011)
0.0 5.1 GO:0000775 chromosome, centromeric region(GO:0000775)
0.0 0.4 GO:0000177 cytoplasmic exosome (RNase complex)(GO:0000177)
0.0 0.8 GO:0035145 exon-exon junction complex(GO:0035145)
0.0 1.8 GO:0005844 polysome(GO:0005844)
0.0 0.3 GO:0005677 chromatin silencing complex(GO:0005677)
0.0 0.1 GO:0005594 collagen type IX trimer(GO:0005594)
0.0 0.5 GO:0005839 proteasome core complex(GO:0005839)
0.0 0.4 GO:0035861 site of double-strand break(GO:0035861)
0.0 0.6 GO:0005697 telomerase holoenzyme complex(GO:0005697)
0.0 0.4 GO:0017101 aminoacyl-tRNA synthetase multienzyme complex(GO:0017101)
0.0 0.4 GO:0042470 melanosome(GO:0042470) pigment granule(GO:0048770)
0.0 3.2 GO:0043235 receptor complex(GO:0043235)
0.0 1.7 GO:0031594 neuromuscular junction(GO:0031594)
0.0 0.8 GO:0015030 Cajal body(GO:0015030)
0.0 2.1 GO:0000932 cytoplasmic mRNA processing body(GO:0000932)
0.0 0.6 GO:0031307 integral component of mitochondrial outer membrane(GO:0031307)
0.0 1.8 GO:0016605 PML body(GO:0016605)
0.0 0.1 GO:0035339 SPOTS complex(GO:0035339)
0.0 0.5 GO:0005680 anaphase-promoting complex(GO:0005680)
0.0 0.3 GO:0036038 MKS complex(GO:0036038)
0.0 0.3 GO:0044300 cerebellar mossy fiber(GO:0044300)
0.0 0.6 GO:0005938 cell cortex(GO:0005938)
0.0 1.5 GO:1990204 oxidoreductase complex(GO:1990204)
0.0 0.0 GO:0044292 dendrite terminus(GO:0044292)
0.0 5.8 GO:0005925 focal adhesion(GO:0005925)
0.0 0.1 GO:0097431 mitotic spindle pole(GO:0097431)
0.0 0.0 GO:0008091 spectrin(GO:0008091)
0.0 0.5 GO:0030119 AP-type membrane coat adaptor complex(GO:0030119)
0.0 0.1 GO:0097443 sorting endosome(GO:0097443)
0.0 1.0 GO:0019005 SCF ubiquitin ligase complex(GO:0019005)
0.0 0.1 GO:0005744 mitochondrial inner membrane presequence translocase complex(GO:0005744)
0.0 0.5 GO:0042645 nucleoid(GO:0009295) mitochondrial nucleoid(GO:0042645)
0.0 72.9 GO:0005634 nucleus(GO:0005634)
0.0 0.7 GO:0055037 recycling endosome(GO:0055037)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
4.3 21.5 GO:0005344 oxygen transporter activity(GO:0005344)
2.3 7.0 GO:0004489 methylenetetrahydrofolate reductase (NAD(P)H) activity(GO:0004489)
1.6 7.9 GO:0043532 angiostatin binding(GO:0043532)
1.5 9.2 GO:0046912 transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer(GO:0046912)
1.3 3.9 GO:0042936 dipeptide transporter activity(GO:0042936)
1.1 3.3 GO:0003987 acetate-CoA ligase activity(GO:0003987)
1.1 3.2 GO:0004774 succinate-CoA ligase activity(GO:0004774)
1.0 34.2 GO:1990841 promoter-specific chromatin binding(GO:1990841)
0.9 15.2 GO:0051010 microtubule plus-end binding(GO:0051010)
0.9 3.5 GO:0008142 oxysterol binding(GO:0008142)
0.8 7.6 GO:0038062 protein tyrosine kinase collagen receptor activity(GO:0038062)
0.8 2.4 GO:0071936 coreceptor activity involved in Wnt signaling pathway(GO:0071936)
0.8 2.3 GO:0036132 13-prostaglandin reductase activity(GO:0036132) 15-oxoprostaglandin 13-oxidase activity(GO:0047522)
0.7 2.2 GO:0031871 proteinase activated receptor binding(GO:0031871)
0.7 3.5 GO:0072542 protein phosphatase activator activity(GO:0072542)
0.7 1.4 GO:0034190 apolipoprotein receptor binding(GO:0034190)
0.7 6.7 GO:0004691 cAMP-dependent protein kinase activity(GO:0004691)
0.6 3.2 GO:1904047 S-adenosyl-L-methionine binding(GO:1904047)
0.6 1.9 GO:0034437 glycoprotein transporter activity(GO:0034437)
0.6 3.1 GO:0035174 histone serine kinase activity(GO:0035174)
0.6 10.9 GO:0001134 transcription factor activity, transcription factor recruiting(GO:0001134)
0.6 1.8 GO:0036004 GAF domain binding(GO:0036004)
0.6 1.8 GO:0016015 morphogen activity(GO:0016015)
0.6 3.0 GO:0035240 dopamine binding(GO:0035240)
0.6 1.7 GO:0003996 acyl-CoA ligase activity(GO:0003996) CoA-ligase activity(GO:0016405)
0.6 11.7 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.5 1.6 GO:0035575 histone demethylase activity (H4-K20 specific)(GO:0035575)
0.5 7.5 GO:0044323 retinoic acid-responsive element binding(GO:0044323)
0.5 1.5 GO:0046538 bisphosphoglycerate mutase activity(GO:0004082) phosphoglycerate mutase activity(GO:0004619) 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase activity(GO:0046538)
0.5 2.0 GO:0004921 interleukin-11 receptor activity(GO:0004921) interleukin-11 binding(GO:0019970)
0.5 1.8 GO:0008131 primary amine oxidase activity(GO:0008131)
0.5 3.2 GO:0004614 phosphoglucomutase activity(GO:0004614)
0.4 3.1 GO:0015016 [heparan sulfate]-glucosamine N-sulfotransferase activity(GO:0015016)
0.4 1.3 GO:0031752 D5 dopamine receptor binding(GO:0031752)
0.4 2.1 GO:0019960 C-X3-C chemokine binding(GO:0019960) neuregulin binding(GO:0038132)
0.4 7.7 GO:0001848 complement binding(GO:0001848)
0.4 1.2 GO:0001225 RNA polymerase II transcription coactivator binding(GO:0001225)
0.4 1.2 GO:0004743 pyruvate kinase activity(GO:0004743)
0.4 1.9 GO:0016941 natriuretic peptide receptor activity(GO:0016941)
0.4 2.2 GO:0000155 phosphorelay sensor kinase activity(GO:0000155)
0.3 3.4 GO:0008379 thioredoxin peroxidase activity(GO:0008379)
0.3 1.7 GO:0004165 dodecenoyl-CoA delta-isomerase activity(GO:0004165)
0.3 3.3 GO:0004445 inositol-polyphosphate 5-phosphatase activity(GO:0004445) inositol trisphosphate phosphatase activity(GO:0046030)
0.3 1.3 GO:0017077 oxidative phosphorylation uncoupler activity(GO:0017077)
0.3 1.6 GO:0005127 ciliary neurotrophic factor receptor binding(GO:0005127)
0.3 2.3 GO:0004523 RNA-DNA hybrid ribonuclease activity(GO:0004523)
0.3 1.3 GO:0008422 beta-glucosidase activity(GO:0008422)
0.3 0.9 GO:0000822 inositol hexakisphosphate binding(GO:0000822)
0.3 1.2 GO:0043176 amine binding(GO:0043176)
0.3 0.9 GO:0004415 hyalurononglucosaminidase activity(GO:0004415)
0.3 4.0 GO:0017154 semaphorin receptor activity(GO:0017154)
0.3 1.4 GO:0031014 troponin T binding(GO:0031014)
0.3 3.3 GO:0070742 C2H2 zinc finger domain binding(GO:0070742)
0.3 1.1 GO:0048408 epidermal growth factor binding(GO:0048408)
0.3 2.2 GO:0005095 GTPase inhibitor activity(GO:0005095)
0.3 7.7 GO:0032266 phosphatidylinositol-3-phosphate binding(GO:0032266)
0.3 0.8 GO:0050501 hyaluronan synthase activity(GO:0050501)
0.3 1.6 GO:0016532 superoxide dismutase copper chaperone activity(GO:0016532)
0.3 1.6 GO:0034452 dynactin binding(GO:0034452)
0.3 47.0 GO:0001078 transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078)
0.2 2.0 GO:0061133 endopeptidase activator activity(GO:0061133)
0.2 1.2 GO:0005052 peroxisome matrix targeting signal-1 binding(GO:0005052)
0.2 1.1 GO:0004322 ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724)
0.2 0.7 GO:0004769 steroid delta-isomerase activity(GO:0004769)
0.2 3.4 GO:0005540 hyaluronic acid binding(GO:0005540)
0.2 9.2 GO:0001965 G-protein alpha-subunit binding(GO:0001965)
0.2 0.6 GO:0019966 interleukin-1 binding(GO:0019966)
0.2 3.7 GO:0036312 phosphatidylinositol 3-kinase regulatory subunit binding(GO:0036312)
0.2 1.0 GO:1904288 BAT3 complex binding(GO:1904288)
0.2 3.4 GO:0030247 pattern binding(GO:0001871) polysaccharide binding(GO:0030247)
0.2 2.0 GO:0004185 serine-type carboxypeptidase activity(GO:0004185)
0.2 2.4 GO:0009931 calcium-dependent protein serine/threonine kinase activity(GO:0009931)
0.2 7.4 GO:0017091 AU-rich element binding(GO:0017091)
0.2 5.2 GO:0080025 phosphatidylinositol-3,5-bisphosphate binding(GO:0080025)
0.2 5.7 GO:0008574 ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574)
0.2 0.6 GO:0016964 alpha-2 macroglobulin receptor activity(GO:0016964)
0.2 2.7 GO:0022889 L-serine transmembrane transporter activity(GO:0015194) serine transmembrane transporter activity(GO:0022889)
0.2 2.7 GO:0016638 oxidoreductase activity, acting on the CH-NH2 group of donors(GO:0016638)
0.2 4.5 GO:0098632 protein binding involved in cell-cell adhesion(GO:0098632)
0.2 0.6 GO:0042954 lipoprotein transporter activity(GO:0042954)
0.2 1.8 GO:0001055 RNA polymerase II activity(GO:0001055)
0.2 2.7 GO:0016805 dipeptidase activity(GO:0016805)
0.2 1.2 GO:0051400 BH domain binding(GO:0051400)
0.2 2.4 GO:0030215 semaphorin receptor binding(GO:0030215)
0.2 1.3 GO:0046934 phosphatidylinositol-4,5-bisphosphate 3-kinase activity(GO:0046934) phosphatidylinositol bisphosphate kinase activity(GO:0052813)
0.2 1.6 GO:0038191 neuropilin binding(GO:0038191)
0.2 0.6 GO:0016833 oxo-acid-lyase activity(GO:0016833)
0.2 0.5 GO:0016748 succinyltransferase activity(GO:0016748)
0.2 3.9 GO:0070577 lysine-acetylated histone binding(GO:0070577)
0.2 0.9 GO:0015277 kainate selective glutamate receptor activity(GO:0015277)
0.2 0.5 GO:0061628 H3K27me3 modified histone binding(GO:0061628)
0.1 1.2 GO:0016670 oxidoreductase activity, acting on a sulfur group of donors, oxygen as acceptor(GO:0016670)
0.1 0.1 GO:0000992 polymerase III regulatory region sequence-specific DNA binding(GO:0000992) RNA polymerase III type 1 promoter sequence-specific DNA binding(GO:0001002) RNA polymerase III type 2 promoter sequence-specific DNA binding(GO:0001003)
0.1 1.4 GO:0003964 telomerase activity(GO:0003720) RNA-directed DNA polymerase activity(GO:0003964)
0.1 0.4 GO:0071568 UFM1 transferase activity(GO:0071568)
0.1 1.8 GO:0070513 death domain binding(GO:0070513)
0.1 4.5 GO:0030676 Rac guanyl-nucleotide exchange factor activity(GO:0030676)
0.1 0.8 GO:0044547 DNA topoisomerase binding(GO:0044547)
0.1 3.7 GO:0043014 alpha-tubulin binding(GO:0043014)
0.1 13.0 GO:0033613 activating transcription factor binding(GO:0033613)
0.1 1.9 GO:0000014 single-stranded DNA endodeoxyribonuclease activity(GO:0000014)
0.1 0.4 GO:0017099 very-long-chain-acyl-CoA dehydrogenase activity(GO:0017099)
0.1 0.5 GO:0004703 G-protein coupled receptor kinase activity(GO:0004703)
0.1 0.9 GO:0045505 dynein intermediate chain binding(GO:0045505)
0.1 2.7 GO:0004697 protein kinase C activity(GO:0004697)
0.1 1.7 GO:0045499 chemorepellent activity(GO:0045499)
0.1 0.4 GO:0016716 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, another compound as one donor, and incorporation of one atom of oxygen(GO:0016716)
0.1 1.0 GO:0005519 cytoskeletal regulatory protein binding(GO:0005519)
0.1 2.6 GO:0004708 MAP kinase kinase activity(GO:0004708)
0.1 0.5 GO:0005093 Rab GDP-dissociation inhibitor activity(GO:0005093)
0.1 3.8 GO:0051183 vitamin transporter activity(GO:0051183)
0.1 0.8 GO:0015129 lactate transmembrane transporter activity(GO:0015129)
0.1 17.1 GO:0001047 core promoter binding(GO:0001047)
0.1 2.3 GO:0000146 microfilament motor activity(GO:0000146)
0.1 0.3 GO:0008527 taste receptor activity(GO:0008527)
0.1 0.9 GO:0005131 growth hormone receptor binding(GO:0005131)
0.1 4.9 GO:0008536 Ran GTPase binding(GO:0008536)
0.1 1.1 GO:0015217 ATP transmembrane transporter activity(GO:0005347) ADP transmembrane transporter activity(GO:0015217)
0.1 0.6 GO:0004634 phosphopyruvate hydratase activity(GO:0004634)
0.1 1.4 GO:0043495 protein anchor(GO:0043495)
0.1 2.6 GO:0043236 laminin binding(GO:0043236)
0.1 7.4 GO:0001158 enhancer sequence-specific DNA binding(GO:0001158)
0.1 0.6 GO:0008321 Ral guanyl-nucleotide exchange factor activity(GO:0008321)
0.1 4.2 GO:0031492 nucleosomal DNA binding(GO:0031492)
0.1 0.2 GO:0046975 histone methyltransferase activity (H3-K36 specific)(GO:0046975)
0.1 0.6 GO:0003910 DNA ligase activity(GO:0003909) DNA ligase (ATP) activity(GO:0003910)
0.1 0.8 GO:0001618 virus receptor activity(GO:0001618)
0.1 0.8 GO:1990380 Lys48-specific deubiquitinase activity(GO:1990380)
0.1 0.8 GO:0031432 titin binding(GO:0031432)
0.1 0.9 GO:0008190 eukaryotic initiation factor 4E binding(GO:0008190)
0.1 4.0 GO:0017112 Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.1 3.7 GO:0031624 ubiquitin conjugating enzyme binding(GO:0031624)
0.1 0.7 GO:0003747 translation release factor activity(GO:0003747) translation termination factor activity(GO:0008079)
0.1 2.9 GO:0050699 WW domain binding(GO:0050699)
0.1 0.7 GO:0019788 NEDD8 transferase activity(GO:0019788)
0.1 1.1 GO:0047372 acylglycerol lipase activity(GO:0047372)
0.1 1.9 GO:0070006 metalloaminopeptidase activity(GO:0070006)
0.1 1.1 GO:0005092 GDP-dissociation inhibitor activity(GO:0005092)
0.1 1.6 GO:0008353 RNA polymerase II carboxy-terminal domain kinase activity(GO:0008353)
0.1 20.0 GO:0000978 RNA polymerase II core promoter proximal region sequence-specific DNA binding(GO:0000978)
0.1 0.2 GO:0008330 protein tyrosine/threonine phosphatase activity(GO:0008330)
0.1 0.9 GO:0016861 intramolecular oxidoreductase activity, interconverting aldoses and ketoses(GO:0016861)
0.1 0.3 GO:0016812 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides(GO:0016812)
0.1 3.3 GO:0070063 RNA polymerase binding(GO:0070063)
0.1 0.5 GO:0004984 olfactory receptor activity(GO:0004984)
0.1 0.7 GO:0035251 UDP-glucosyltransferase activity(GO:0035251)
0.1 0.9 GO:0030306 ADP-ribosylation factor binding(GO:0030306)
0.1 0.3 GO:0004046 aminoacylase activity(GO:0004046)
0.1 0.5 GO:0036402 proteasome-activating ATPase activity(GO:0036402)
0.1 2.8 GO:0005070 SH3/SH2 adaptor activity(GO:0005070)
0.1 2.6 GO:0042169 SH2 domain binding(GO:0042169)
0.1 0.4 GO:0086056 voltage-gated calcium channel activity involved in AV node cell action potential(GO:0086056)
0.1 0.4 GO:0004095 carnitine O-palmitoyltransferase activity(GO:0004095) O-palmitoyltransferase activity(GO:0016416)
0.1 0.1 GO:0030375 thyroid hormone receptor coactivator activity(GO:0030375)
0.1 0.4 GO:1990948 ligase inhibitor activity(GO:0055104) ubiquitin ligase inhibitor activity(GO:1990948)
0.1 0.2 GO:0008113 peptide-methionine (S)-S-oxide reductase activity(GO:0008113)
0.1 3.3 GO:0003777 microtubule motor activity(GO:0003777)
0.1 0.4 GO:0008294 calcium- and calmodulin-responsive adenylate cyclase activity(GO:0008294)
0.1 1.5 GO:0008266 poly(U) RNA binding(GO:0008266)
0.1 0.8 GO:0016500 protein-hormone receptor activity(GO:0016500)
0.1 0.4 GO:0008417 fucosyltransferase activity(GO:0008417)
0.1 1.0 GO:0043395 heparan sulfate proteoglycan binding(GO:0043395)
0.1 2.7 GO:0005518 collagen binding(GO:0005518)
0.1 0.2 GO:0047192 1-alkylglycerophosphocholine O-acetyltransferase activity(GO:0047192)
0.1 0.5 GO:0004143 diacylglycerol kinase activity(GO:0004143)
0.1 0.8 GO:0001103 RNA polymerase II repressing transcription factor binding(GO:0001103)
0.1 8.5 GO:0004386 helicase activity(GO:0004386)
0.1 1.5 GO:0031369 translation initiation factor binding(GO:0031369)
0.1 0.3 GO:0031995 insulin-like growth factor II binding(GO:0031995)
0.1 0.6 GO:0005078 MAP-kinase scaffold activity(GO:0005078)
0.1 0.4 GO:0004865 protein serine/threonine phosphatase inhibitor activity(GO:0004865)
0.0 1.0 GO:0008308 voltage-gated anion channel activity(GO:0008308)
0.0 0.3 GO:0004689 phosphorylase kinase activity(GO:0004689)
0.0 0.3 GO:0043024 ribosomal small subunit binding(GO:0043024)
0.0 1.3 GO:0018024 histone-lysine N-methyltransferase activity(GO:0018024)
0.0 0.5 GO:0001968 fibronectin binding(GO:0001968)
0.0 0.2 GO:0045545 syndecan binding(GO:0045545)
0.0 0.1 GO:0036435 K48-linked polyubiquitin binding(GO:0036435)
0.0 0.7 GO:0009982 pseudouridine synthase activity(GO:0009982)
0.0 0.5 GO:0034450 ubiquitin-ubiquitin ligase activity(GO:0034450)
0.0 0.2 GO:0051377 mannose-ethanolamine phosphotransferase activity(GO:0051377)
0.0 3.1 GO:0003714 transcription corepressor activity(GO:0003714)
0.0 1.0 GO:0000062 fatty-acyl-CoA binding(GO:0000062)
0.0 1.1 GO:0008198 ferrous iron binding(GO:0008198)
0.0 2.2 GO:0003730 mRNA 3'-UTR binding(GO:0003730)
0.0 0.9 GO:0004709 MAP kinase kinase kinase activity(GO:0004709)
0.0 0.2 GO:0097001 ceramide binding(GO:0097001)
0.0 0.2 GO:0004719 protein-L-isoaspartate (D-aspartate) O-methyltransferase activity(GO:0004719)
0.0 0.4 GO:0008526 phosphatidylinositol transporter activity(GO:0008526)
0.0 0.3 GO:0031811 G-protein coupled nucleotide receptor binding(GO:0031811) P2Y1 nucleotide receptor binding(GO:0031812)
0.0 1.7 GO:0003743 translation initiation factor activity(GO:0003743)
0.0 0.7 GO:0008483 transaminase activity(GO:0008483)
0.0 0.6 GO:0008188 neuropeptide receptor activity(GO:0008188)
0.0 1.5 GO:0003727 single-stranded RNA binding(GO:0003727)
0.0 0.2 GO:0001972 retinoic acid binding(GO:0001972)
0.0 0.5 GO:0034987 immunoglobulin receptor binding(GO:0034987)
0.0 0.5 GO:0005104 fibroblast growth factor receptor binding(GO:0005104)
0.0 0.1 GO:0032137 guanine/thymine mispair binding(GO:0032137)
0.0 0.1 GO:0004758 serine C-palmitoyltransferase activity(GO:0004758) C-palmitoyltransferase activity(GO:0016454)
0.0 0.2 GO:0070016 armadillo repeat domain binding(GO:0070016)
0.0 1.2 GO:0031593 polyubiquitin binding(GO:0031593)
0.0 0.3 GO:0016922 ligand-dependent nuclear receptor binding(GO:0016922)
0.0 0.1 GO:0003705 transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0003705)
0.0 3.6 GO:0042393 histone binding(GO:0042393)
0.0 0.1 GO:0004359 glutaminase activity(GO:0004359)
0.0 1.1 GO:0061631 ubiquitin conjugating enzyme activity(GO:0061631)
0.0 0.1 GO:0044020 snoRNP binding(GO:0030519) histone methyltransferase activity (H4-R3 specific)(GO:0044020)
0.0 0.1 GO:1990381 ubiquitin-specific protease binding(GO:1990381)
0.0 0.4 GO:0042826 histone deacetylase binding(GO:0042826)
0.0 0.4 GO:0004559 alpha-mannosidase activity(GO:0004559)
0.0 0.6 GO:0004012 phospholipid-translocating ATPase activity(GO:0004012)
0.0 4.7 GO:0061630 ubiquitin protein ligase activity(GO:0061630)
0.0 0.5 GO:0051537 2 iron, 2 sulfur cluster binding(GO:0051537)
0.0 2.5 GO:0030165 PDZ domain binding(GO:0030165)
0.0 0.2 GO:0070290 N-acylphosphatidylethanolamine-specific phospholipase D activity(GO:0070290)
0.0 0.5 GO:0004298 threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
0.0 0.5 GO:0030971 receptor tyrosine kinase binding(GO:0030971)
0.0 0.2 GO:0030371 translation repressor activity(GO:0030371)
0.0 0.0 GO:0005138 interleukin-6 receptor binding(GO:0005138)
0.0 0.7 GO:0003682 chromatin binding(GO:0003682)
0.0 0.2 GO:0031078 histone deacetylase activity (H3-K14 specific)(GO:0031078) NAD-dependent histone deacetylase activity (H3-K14 specific)(GO:0032041)
0.0 1.2 GO:0005253 anion channel activity(GO:0005253)
0.0 0.4 GO:0001784 phosphotyrosine binding(GO:0001784)
0.0 0.5 GO:0042562 hormone binding(GO:0042562)
0.0 0.6 GO:0019707 protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)
0.0 0.6 GO:0004712 protein serine/threonine/tyrosine kinase activity(GO:0004712)
0.0 0.0 GO:0071987 WD40-repeat domain binding(GO:0071987)
0.0 7.1 GO:0019904 protein domain specific binding(GO:0019904)
0.0 0.9 GO:0008080 N-acetyltransferase activity(GO:0008080)
0.0 0.1 GO:0031800 type 3 metabotropic glutamate receptor binding(GO:0031800)
0.0 0.7 GO:0008138 protein tyrosine/serine/threonine phosphatase activity(GO:0008138)
0.0 0.7 GO:0015485 cholesterol binding(GO:0015485)
0.0 1.1 GO:0003713 transcription coactivator activity(GO:0003713)
0.0 0.2 GO:0019103 pyrimidine nucleotide binding(GO:0019103)
0.0 0.1 GO:0047134 protein-disulfide reductase activity(GO:0047134)
0.0 0.2 GO:0004435 phosphatidylinositol phospholipase C activity(GO:0004435)
0.0 0.1 GO:0005243 gap junction channel activity(GO:0005243)
0.0 0.1 GO:0030628 pre-mRNA 3'-splice site binding(GO:0030628)
0.0 0.0 GO:0030249 cyclase regulator activity(GO:0010851) guanylate cyclase regulator activity(GO:0030249)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
1.1 34.6 PID_HEDGEHOG_2PATHWAY Signaling events mediated by the Hedgehog family
0.7 3.7 PID_PDGFRA_PATHWAY PDGFR-alpha signaling pathway
0.5 22.9 PID_AURORA_B_PATHWAY Aurora B signaling
0.4 13.3 PID_WNT_SIGNALING_PATHWAY Wnt signaling network
0.3 12.6 PID_DELTA_NP63_PATHWAY Validated transcriptional targets of deltaNp63 isoforms
0.3 5.7 PID_EPHA2_FWD_PATHWAY EPHA2 forward signaling
0.2 0.9 ST_IL_13_PATHWAY Interleukin 13 (IL-13) Pathway
0.2 1.5 PID_INTEGRIN4_PATHWAY Alpha6 beta4 integrin-ligand interactions
0.2 4.9 PID_UPA_UPAR_PATHWAY Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling
0.2 5.7 PID_P38_MK2_PATHWAY p38 signaling mediated by MAPKAP kinases
0.2 6.1 SIG_REGULATION_OF_THE_ACTIN_CYTOSKELETON_BY_RHO_GTPASES Genes related to regulation of the actin cytoskeleton
0.2 1.7 PID_ALK2_PATHWAY ALK2 signaling events
0.1 6.6 PID_RHOA_PATHWAY RhoA signaling pathway
0.1 11.2 PID_E2F_PATHWAY E2F transcription factor network
0.1 7.2 PID_CASPASE_PATHWAY Caspase cascade in apoptosis
0.1 2.7 PID_HDAC_CLASSIII_PATHWAY Signaling events mediated by HDAC Class III
0.1 8.7 SIG_PIP3_SIGNALING_IN_CARDIAC_MYOCTES Genes related to PIP3 signaling in cardiac myocytes
0.1 0.6 PID_PTP1B_PATHWAY Signaling events mediated by PTP1B
0.1 8.0 PID_RHOA_REG_PATHWAY Regulation of RhoA activity
0.1 1.7 PID_ERB_GENOMIC_PATHWAY Validated nuclear estrogen receptor beta network
0.1 2.9 PID_TOLL_ENDOGENOUS_PATHWAY Endogenous TLR signaling
0.1 0.6 SA_B_CELL_RECEPTOR_COMPLEXES Antigen binding to B cell receptors activates protein tyrosine kinases, such as the Src family, which ultimate activate MAP kinases.
0.1 0.7 PID_IL4_2PATHWAY IL4-mediated signaling events
0.1 0.7 PID_IL5_PATHWAY IL5-mediated signaling events
0.1 5.3 PID_AR_PATHWAY Coregulation of Androgen receptor activity
0.1 3.0 PID_RAC1_REG_PATHWAY Regulation of RAC1 activity
0.1 1.4 PID_HIV_NEF_PATHWAY HIV-1 Nef: Negative effector of Fas and TNF-alpha
0.1 2.1 PID_RAS_PATHWAY Regulation of Ras family activation
0.1 0.9 PID_CD40_PATHWAY CD40/CD40L signaling
0.1 1.5 ST_JNK_MAPK_PATHWAY JNK MAPK Pathway
0.1 1.4 PID_ERBB4_PATHWAY ErbB4 signaling events
0.1 2.6 PID_AR_TF_PATHWAY Regulation of Androgen receptor activity
0.0 0.5 PID_ECADHERIN_KERATINOCYTE_PATHWAY E-cadherin signaling in keratinocytes
0.0 5.8 NABA_ECM_REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.0 1.6 PID_HES_HEY_PATHWAY Notch-mediated HES/HEY network
0.0 0.8 PID_EPHRINB_REV_PATHWAY Ephrin B reverse signaling
0.0 1.5 PID_ERA_GENOMIC_PATHWAY Validated nuclear estrogen receptor alpha network
0.0 0.9 ST_WNT_BETA_CATENIN_PATHWAY Wnt/beta-catenin Pathway
0.0 0.3 PID_S1P_S1P4_PATHWAY S1P4 pathway
0.0 0.7 PID_ATM_PATHWAY ATM pathway
0.0 0.4 PID_LPA4_PATHWAY LPA4-mediated signaling events
0.0 1.2 PID_PLK1_PATHWAY PLK1 signaling events
0.0 0.5 PID_LIS1_PATHWAY Lissencephaly gene (LIS1) in neuronal migration and development
0.0 0.2 PID_P38_MKK3_6PATHWAY p38 MAPK signaling pathway
0.0 0.2 PID_IL1_PATHWAY IL1-mediated signaling events
0.0 0.3 PID_NCADHERIN_PATHWAY N-cadherin signaling events
0.0 0.5 PID_HNF3B_PATHWAY FOXA2 and FOXA3 transcription factor networks
0.0 0.4 PID_FANCONI_PATHWAY Fanconi anemia pathway

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 3.3 REACTOME_ETHANOL_OXIDATION Genes involved in Ethanol oxidation
0.8 7.6 REACTOME_INTRINSIC_PATHWAY Genes involved in Intrinsic Pathway
0.7 19.1 REACTOME_KINESINS Genes involved in Kinesins
0.3 10.5 REACTOME_SIGNALING_BY_HIPPO Genes involved in Signaling by Hippo
0.3 1.0 REACTOME_TRANSLOCATION_OF_ZAP_70_TO_IMMUNOLOGICAL_SYNAPSE Genes involved in Translocation of ZAP-70 to Immunological synapse
0.3 3.6 REACTOME_IL_6_SIGNALING Genes involved in Interleukin-6 signaling
0.3 6.9 REACTOME_TGF_BETA_RECEPTOR_SIGNALING_IN_EMT_EPITHELIAL_TO_MESENCHYMAL_TRANSITION Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.3 1.7 REACTOME_DOWNREGULATION_OF_ERBB2_ERBB3_SIGNALING Genes involved in Downregulation of ERBB2:ERBB3 signaling
0.3 7.1 REACTOME_G0_AND_EARLY_G1 Genes involved in G0 and Early G1
0.3 3.8 REACTOME_NOTCH_HLH_TRANSCRIPTION_PATHWAY Genes involved in Notch-HLH transcription pathway
0.3 3.0 REACTOME_AMINE_DERIVED_HORMONES Genes involved in Amine-derived hormones
0.3 6.5 REACTOME_REGULATION_OF_GENE_EXPRESSION_IN_BETA_CELLS Genes involved in Regulation of gene expression in beta cells
0.2 6.8 REACTOME_YAP1_AND_WWTR1_TAZ_STIMULATED_GENE_EXPRESSION Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.2 6.7 REACTOME_PACKAGING_OF_TELOMERE_ENDS Genes involved in Packaging Of Telomere Ends
0.2 6.2 REACTOME_FATTY_ACYL_COA_BIOSYNTHESIS Genes involved in Fatty Acyl-CoA Biosynthesis
0.2 1.8 REACTOME_SIGNALING_BY_NODAL Genes involved in Signaling by NODAL
0.2 2.7 REACTOME_ACTIVATION_OF_BH3_ONLY_PROTEINS Genes involved in Activation of BH3-only proteins
0.1 3.2 REACTOME_CITRIC_ACID_CYCLE_TCA_CYCLE Genes involved in Citric acid cycle (TCA cycle)
0.1 2.5 REACTOME_P38MAPK_EVENTS Genes involved in p38MAPK events
0.1 4.2 REACTOME_IL_RECEPTOR_SHC_SIGNALING Genes involved in Interleukin receptor SHC signaling
0.1 2.1 REACTOME_MITOCHONDRIAL_FATTY_ACID_BETA_OXIDATION Genes involved in Mitochondrial Fatty Acid Beta-Oxidation
0.1 1.1 REACTOME_INTERACTIONS_OF_VPR_WITH_HOST_CELLULAR_PROTEINS Genes involved in Interactions of Vpr with host cellular proteins
0.1 7.6 REACTOME_NUCLEAR_RECEPTOR_TRANSCRIPTION_PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.1 1.1 REACTOME_CDC6_ASSOCIATION_WITH_THE_ORC_ORIGIN_COMPLEX Genes involved in CDC6 association with the ORC:origin complex
0.1 1.8 REACTOME_DEGRADATION_OF_THE_EXTRACELLULAR_MATRIX Genes involved in Degradation of the extracellular matrix
0.1 1.2 REACTOME_NONSENSE_MEDIATED_DECAY_ENHANCED_BY_THE_EXON_JUNCTION_COMPLEX Genes involved in Nonsense Mediated Decay Enhanced by the Exon Junction Complex
0.1 4.4 REACTOME_SEMA4D_IN_SEMAPHORIN_SIGNALING Genes involved in Sema4D in semaphorin signaling
0.1 1.4 REACTOME_PECAM1_INTERACTIONS Genes involved in PECAM1 interactions
0.1 4.2 REACTOME_HS_GAG_BIOSYNTHESIS Genes involved in HS-GAG biosynthesis
0.1 2.2 REACTOME_DCC_MEDIATED_ATTRACTIVE_SIGNALING Genes involved in DCC mediated attractive signaling
0.1 1.6 REACTOME_HYALURONAN_METABOLISM Genes involved in Hyaluronan metabolism
0.1 8.7 REACTOME_CLASS_B_2_SECRETIN_FAMILY_RECEPTORS Genes involved in Class B/2 (Secretin family receptors)
0.1 3.1 REACTOME_SMAD2_SMAD3_SMAD4_HETEROTRIMER_REGULATES_TRANSCRIPTION Genes involved in SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription
0.1 2.0 REACTOME_RNA_POL_I_PROMOTER_OPENING Genes involved in RNA Polymerase I Promoter Opening
0.1 1.9 REACTOME_ABCA_TRANSPORTERS_IN_LIPID_HOMEOSTASIS Genes involved in ABCA transporters in lipid homeostasis
0.1 0.8 REACTOME_BILE_SALT_AND_ORGANIC_ANION_SLC_TRANSPORTERS Genes involved in Bile salt and organic anion SLC transporters
0.1 6.3 REACTOME_G_ALPHA1213_SIGNALLING_EVENTS Genes involved in G alpha (12/13) signalling events
0.1 1.4 REACTOME_VIRAL_MESSENGER_RNA_SYNTHESIS Genes involved in Viral Messenger RNA Synthesis
0.1 2.3 REACTOME_PIP3_ACTIVATES_AKT_SIGNALING Genes involved in PIP3 activates AKT signaling
0.1 1.5 REACTOME_INTEGRIN_CELL_SURFACE_INTERACTIONS Genes involved in Integrin cell surface interactions
0.1 0.8 REACTOME_INHIBITION_OF_INSULIN_SECRETION_BY_ADRENALINE_NORADRENALINE Genes involved in Inhibition of Insulin Secretion by Adrenaline/Noradrenaline
0.1 0.4 REACTOME_ACTIVATED_AMPK_STIMULATES_FATTY_ACID_OXIDATION_IN_MUSCLE Genes involved in Activated AMPK stimulates fatty-acid oxidation in muscle
0.1 0.8 REACTOME_APOPTOSIS_INDUCED_DNA_FRAGMENTATION Genes involved in Apoptosis induced DNA fragmentation
0.1 4.4 REACTOME_APC_C_CDH1_MEDIATED_DEGRADATION_OF_CDC20_AND_OTHER_APC_C_CDH1_TARGETED_PROTEINS_IN_LATE_MITOSIS_EARLY_G1 Genes involved in APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1
0.1 0.5 REACTOME_ACTIVATION_OF_CHAPERONE_GENES_BY_ATF6_ALPHA Genes involved in Activation of Chaperone Genes by ATF6-alpha
0.1 1.4 REACTOME_RNA_POL_III_TRANSCRIPTION_INITIATION_FROM_TYPE_2_PROMOTER Genes involved in RNA Polymerase III Transcription Initiation From Type 2 Promoter
0.1 1.5 REACTOME_MEIOTIC_RECOMBINATION Genes involved in Meiotic Recombination
0.1 0.5 REACTOME_SIGNALING_BY_FGFR3_MUTANTS Genes involved in Signaling by FGFR3 mutants
0.1 1.0 REACTOME_IONOTROPIC_ACTIVITY_OF_KAINATE_RECEPTORS Genes involved in Ionotropic activity of Kainate Receptors
0.1 1.3 REACTOME_SYNTHESIS_OF_PC Genes involved in Synthesis of PC
0.1 3.7 REACTOME_TRANSCRIPTIONAL_REGULATION_OF_WHITE_ADIPOCYTE_DIFFERENTIATION Genes involved in Transcriptional Regulation of White Adipocyte Differentiation
0.1 1.4 REACTOME_TIGHT_JUNCTION_INTERACTIONS Genes involved in Tight junction interactions
0.1 3.2 REACTOME_METABOLISM_OF_VITAMINS_AND_COFACTORS Genes involved in Metabolism of vitamins and cofactors
0.1 1.3 REACTOME_STRIATED_MUSCLE_CONTRACTION Genes involved in Striated Muscle Contraction
0.0 1.1 REACTOME_METABOLISM_OF_PORPHYRINS Genes involved in Metabolism of porphyrins
0.0 8.9 REACTOME_ANTIGEN_PROCESSING_UBIQUITINATION_PROTEASOME_DEGRADATION Genes involved in Antigen processing: Ubiquitination & Proteasome degradation
0.0 3.3 REACTOME_ANTIVIRAL_MECHANISM_BY_IFN_STIMULATED_GENES Genes involved in Antiviral mechanism by IFN-stimulated genes
0.0 1.5 REACTOME_IRON_UPTAKE_AND_TRANSPORT Genes involved in Iron uptake and transport
0.0 1.5 REACTOME_EFFECTS_OF_PIP2_HYDROLYSIS Genes involved in Effects of PIP2 hydrolysis
0.0 0.2 REACTOME_HOMOLOGOUS_RECOMBINATION_REPAIR_OF_REPLICATION_INDEPENDENT_DOUBLE_STRAND_BREAKS Genes involved in Homologous recombination repair of replication-independent double-strand breaks
0.0 0.5 REACTOME_RESOLUTION_OF_AP_SITES_VIA_THE_SINGLE_NUCLEOTIDE_REPLACEMENT_PATHWAY Genes involved in Resolution of AP sites via the single-nucleotide replacement pathway
0.0 3.2 REACTOME_MITOTIC_PROMETAPHASE Genes involved in Mitotic Prometaphase
0.0 0.3 REACTOME_SYNTHESIS_SECRETION_AND_INACTIVATION_OF_GIP Genes involved in Synthesis, Secretion, and Inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)
0.0 0.9 REACTOME_OTHER_SEMAPHORIN_INTERACTIONS Genes involved in Other semaphorin interactions
0.0 0.4 REACTOME_ACTIVATION_OF_NF_KAPPAB_IN_B_CELLS Genes involved in Activation of NF-kappaB in B Cells
0.0 0.6 REACTOME_JNK_C_JUN_KINASES_PHOSPHORYLATION_AND_ACTIVATION_MEDIATED_BY_ACTIVATED_HUMAN_TAK1 Genes involved in JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1
0.0 0.8 REACTOME_AMINO_ACID_SYNTHESIS_AND_INTERCONVERSION_TRANSAMINATION Genes involved in Amino acid synthesis and interconversion (transamination)
0.0 0.9 REACTOME_MRNA_SPLICING_MINOR_PATHWAY Genes involved in mRNA Splicing - Minor Pathway
0.0 0.7 REACTOME_CHOLESTEROL_BIOSYNTHESIS Genes involved in Cholesterol biosynthesis
0.0 0.6 REACTOME_PRE_NOTCH_EXPRESSION_AND_PROCESSING Genes involved in Pre-NOTCH Expression and Processing
0.0 0.4 REACTOME_FANCONI_ANEMIA_PATHWAY Genes involved in Fanconi Anemia pathway
0.0 1.9 REACTOME_FACTORS_INVOLVED_IN_MEGAKARYOCYTE_DEVELOPMENT_AND_PLATELET_PRODUCTION Genes involved in Factors involved in megakaryocyte development and platelet production
0.0 1.8 REACTOME_SIGNALING_BY_RHO_GTPASES Genes involved in Signaling by Rho GTPases
0.0 0.2 REACTOME_PURINE_CATABOLISM Genes involved in Purine catabolism
0.0 0.3 REACTOME_SULFUR_AMINO_ACID_METABOLISM Genes involved in Sulfur amino acid metabolism
0.0 0.3 REACTOME_REGULATION_OF_INSULIN_LIKE_GROWTH_FACTOR_IGF_ACTIVITY_BY_INSULIN_LIKE_GROWTH_FACTOR_BINDING_PROTEINS_IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.0 0.4 REACTOME_MEIOSIS Genes involved in Meiosis
0.0 0.7 REACTOME_ACTIVATION_OF_CHAPERONE_GENES_BY_XBP1S Genes involved in Activation of Chaperone Genes by XBP1(S)
0.0 0.6 REACTOME_GOLGI_ASSOCIATED_VESICLE_BIOGENESIS Genes involved in Golgi Associated Vesicle Biogenesis
0.0 0.1 REACTOME_REGULATION_OF_IFNA_SIGNALING Genes involved in Regulation of IFNA signaling
0.0 0.2 REACTOME_ACYL_CHAIN_REMODELLING_OF_PC Genes involved in Acyl chain remodelling of PC
0.0 0.2 REACTOME_IL1_SIGNALING Genes involved in Interleukin-1 signaling