Motif ID: Gata5

Z-value: 0.772


Transcription factors associated with Gata5:

Gene SymbolEntrez IDGene Name
Gata5 ENSMUSG00000015627.5 Gata5



Activity profile for motif Gata5.

activity profile for motif Gata5


Sorted Z-values histogram for motif Gata5

Sorted Z-values for motif Gata5



Network of associatons between targets according to the STRING database.



First level regulatory network of Gata5

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr7_-_103853199 7.481 ENSMUST00000033229.3
Hbb-y
hemoglobin Y, beta-like embryonic chain
chr11_+_32276893 4.317 ENSMUST00000145569.1
Hba-x
hemoglobin X, alpha-like embryonic chain in Hba complex
chr11_+_32276400 4.112 ENSMUST00000020531.2
Hba-x
hemoglobin X, alpha-like embryonic chain in Hba complex
chr14_+_75455957 3.699 ENSMUST00000164848.1
Siah3
seven in absentia homolog 3 (Drosophila)
chr8_+_45658666 3.492 ENSMUST00000134675.1
ENSMUST00000139869.1
ENSMUST00000126067.1
Sorbs2


sorbin and SH3 domain containing 2


chr13_+_108316332 3.282 ENSMUST00000051594.5
Depdc1b
DEP domain containing 1B
chr8_+_45658273 3.176 ENSMUST00000153798.1
Sorbs2
sorbin and SH3 domain containing 2
chr16_-_50432340 3.035 ENSMUST00000066037.6
ENSMUST00000089399.4
ENSMUST00000089404.3
ENSMUST00000114477.1
ENSMUST00000138166.1
Bbx




bobby sox homolog (Drosophila)




chr11_+_95337012 3.030 ENSMUST00000037502.6
Fam117a
family with sequence similarity 117, member A
chr16_-_44558879 2.705 ENSMUST00000114634.1
Boc
biregional cell adhesion molecule-related/down-regulated by oncogenes (Cdon) binding protein
chr13_+_108316395 2.458 ENSMUST00000171178.1
Depdc1b
DEP domain containing 1B
chr7_-_70366735 1.968 ENSMUST00000089565.5
Nr2f2
nuclear receptor subfamily 2, group F, member 2
chr16_-_50330987 1.915 ENSMUST00000114488.1
Bbx
bobby sox homolog (Drosophila)
chr5_+_93093428 1.894 ENSMUST00000074733.7
Sept11
septin 11
chr12_-_27342696 1.850 ENSMUST00000079063.5
Sox11
SRY-box containing gene 11
chr11_-_101551837 1.833 ENSMUST00000017290.4
Brca1
breast cancer 1
chr7_+_67647405 1.625 ENSMUST00000032774.8
ENSMUST00000107471.1
Ttc23

tetratricopeptide repeat domain 23

chr6_-_127109517 1.608 ENSMUST00000039913.8
9630033F20Rik
RIKEN cDNA 9630033F20 gene
chr10_-_26078987 1.562 ENSMUST00000066049.6
Tmem200a
transmembrane protein 200A
chr6_+_34384218 1.420 ENSMUST00000038383.7
ENSMUST00000115051.1
Akr1b10

aldo-keto reductase family 1, member B10 (aldose reductase)

chr15_+_55307743 1.407 ENSMUST00000023053.5
ENSMUST00000110221.2
ENSMUST00000110217.3
Col14a1


collagen, type XIV, alpha 1


chr8_+_53511695 1.324 ENSMUST00000033920.4
Aga
aspartylglucosaminidase
chr3_+_146121655 1.130 ENSMUST00000039450.4
Mcoln3
mucolipin 3
chr9_+_80165079 1.125 ENSMUST00000184480.1
Myo6
myosin VI
chr15_-_50890396 1.083 ENSMUST00000185183.1
Trps1
trichorhinophalangeal syndrome I (human)
chr17_-_46645128 1.069 ENSMUST00000003642.6
Klc4
kinesin light chain 4
chr11_+_97030130 1.038 ENSMUST00000153482.1
Scrn2
secernin 2
chr2_+_71786923 0.972 ENSMUST00000112101.1
ENSMUST00000028522.3
Itga6

integrin alpha 6

chr10_-_92162753 0.971 ENSMUST00000182197.1
Rmst
rhabdomyosarcoma 2 associated transcript (non-coding RNA)
chrX_-_139998519 0.963 ENSMUST00000113007.1
ENSMUST00000033810.7
ENSMUST00000113011.2
ENSMUST00000087400.5
Rbm41



RNA binding motif protein 41



chr11_+_97029925 0.905 ENSMUST00000021249.4
Scrn2
secernin 2
chr15_-_86186136 0.901 ENSMUST00000044332.9
Cerk
ceramide kinase
chr5_-_73191848 0.860 ENSMUST00000176910.1
Fryl
furry homolog-like (Drosophila)
chr1_-_156032948 0.851 ENSMUST00000136397.1
Tor1aip1
torsin A interacting protein 1
chr8_+_67494843 0.823 ENSMUST00000093470.5
ENSMUST00000163856.1
Nat2

N-acetyltransferase 2 (arylamine N-acetyltransferase)

chr7_+_126862431 0.738 ENSMUST00000132808.1
Hirip3
HIRA interacting protein 3
chr16_-_88056176 0.713 ENSMUST00000072256.5
ENSMUST00000023652.8
ENSMUST00000114137.1
Grik1


glutamate receptor, ionotropic, kainate 1


chr11_-_109995775 0.686 ENSMUST00000020948.8
Abca8b
ATP-binding cassette, sub-family A (ABC1), member 8b
chr7_-_4630473 0.669 ENSMUST00000055085.6
Tmem86b
transmembrane protein 86B
chr2_+_150323702 0.661 ENSMUST00000133235.2
Gm10130
predicted gene 10130
chr11_-_109995743 0.651 ENSMUST00000106669.2
Abca8b
ATP-binding cassette, sub-family A (ABC1), member 8b
chr15_-_103251465 0.647 ENSMUST00000133600.1
ENSMUST00000134554.1
ENSMUST00000156927.1
ENSMUST00000149111.1
ENSMUST00000132836.1
Nfe2




nuclear factor, erythroid derived 2




chr9_-_58201705 0.636 ENSMUST00000163200.1
ENSMUST00000165276.1
Islr2

immunoglobulin superfamily containing leucine-rich repeat 2

chr12_-_108893197 0.636 ENSMUST00000161154.1
ENSMUST00000161410.1
Wars

tryptophanyl-tRNA synthetase

chr14_-_63543931 0.634 ENSMUST00000058679.5
Mtmr9
myotubularin related protein 9
chr3_+_4211716 0.631 ENSMUST00000170943.1
Gm8775
predicted gene 8775
chr7_+_27731373 0.611 ENSMUST00000108336.1
Zfp60
zinc finger protein 60
chr10_+_45577811 0.606 ENSMUST00000037044.6
Hace1
HECT domain and ankyrin repeat containing, E3 ubiquitin protein ligase 1
chr15_+_100154379 0.599 ENSMUST00000023768.6
ENSMUST00000108971.2
Dip2b

DIP2 disco-interacting protein 2 homolog B (Drosophila)

chr2_+_84980458 0.590 ENSMUST00000028467.5
Prg2
proteoglycan 2, bone marrow
chr7_-_99238564 0.581 ENSMUST00000064231.7
Mogat2
monoacylglycerol O-acyltransferase 2
chr1_+_135232045 0.577 ENSMUST00000110798.3
Gm4204
predicted gene 4204
chr11_-_87359011 0.575 ENSMUST00000055438.4
Ppm1e
protein phosphatase 1E (PP2C domain containing)
chr1_+_143640664 0.571 ENSMUST00000038252.2
B3galt2
UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 2
chr10_+_100488289 0.550 ENSMUST00000164751.1
Cep290
centrosomal protein 290
chrX_-_8193387 0.546 ENSMUST00000143223.1
ENSMUST00000033509.8
Ebp

phenylalkylamine Ca2+ antagonist (emopamil) binding protein

chrX_-_37104523 0.545 ENSMUST00000130324.1
Upf3b
UPF3 regulator of nonsense transcripts homolog B (yeast)
chr6_+_136954521 0.535 ENSMUST00000137768.1
Pde6h
phosphodiesterase 6H, cGMP-specific, cone, gamma
chr7_-_23947237 0.535 ENSMUST00000086013.2
Gm10175
predicted gene 10175
chr1_+_172376528 0.524 ENSMUST00000052455.2
Pigm
phosphatidylinositol glycan anchor biosynthesis, class M
chr16_-_34095983 0.523 ENSMUST00000114973.1
ENSMUST00000114964.1
Kalrn

kalirin, RhoGEF kinase

chr13_-_62520451 0.507 ENSMUST00000082203.6
ENSMUST00000101547.4
Zfp934

zinc finger protein 934

chr7_-_141434532 0.483 ENSMUST00000133021.1
ENSMUST00000106007.3
ENSMUST00000150026.1
ENSMUST00000133206.2
Slc25a22



solute carrier family 25 (mitochondrial carrier, glutamate), member 22



chr4_+_6191093 0.481 ENSMUST00000029907.5
Ubxn2b
UBX domain protein 2B
chr12_+_95692212 0.477 ENSMUST00000057324.3
Flrt2
fibronectin leucine rich transmembrane protein 2
chr19_-_32061438 0.466 ENSMUST00000096119.4
Asah2
N-acylsphingosine amidohydrolase 2
chr19_-_38819156 0.428 ENSMUST00000025963.7
Noc3l
nucleolar complex associated 3 homolog (S. cerevisiae)
chr3_-_146839365 0.421 ENSMUST00000084614.3
Gm10288
predicted gene 10288
chr6_-_92706145 0.421 ENSMUST00000032093.5
Prickle2
prickle homolog 2 (Drosophila)
chr4_-_119190005 0.410 ENSMUST00000138395.1
ENSMUST00000156746.1
Ermap

erythroblast membrane-associated protein

chr6_-_119330668 0.391 ENSMUST00000112756.1
Lrtm2
leucine-rich repeats and transmembrane domains 2
chr2_+_72476159 0.377 ENSMUST00000102691.4
Cdca7
cell division cycle associated 7
chr2_-_37359274 0.367 ENSMUST00000009174.8
Pdcl
phosducin-like
chr15_+_102406143 0.365 ENSMUST00000170884.1
ENSMUST00000165924.1
ENSMUST00000163709.1
ENSMUST00000001326.6
Sp1



trans-acting transcription factor 1



chr2_-_37359235 0.365 ENSMUST00000112940.1
Pdcl
phosducin-like
chrX_-_37110257 0.346 ENSMUST00000076265.6
Upf3b
UPF3 regulator of nonsense transcripts homolog B (yeast)
chr6_-_119330723 0.337 ENSMUST00000068351.7
Lrtm2
leucine-rich repeats and transmembrane domains 2
chr10_-_116950366 0.335 ENSMUST00000020375.6
Rab3ip
RAB3A interacting protein
chr4_+_111972922 0.324 ENSMUST00000106568.1
ENSMUST00000055014.4
ENSMUST00000163281.1
Skint7


selection and upkeep of intraepithelial T cells 7


chr7_-_141434402 0.323 ENSMUST00000136354.1
Slc25a22
solute carrier family 25 (mitochondrial carrier, glutamate), member 22
chr3_-_94886945 0.316 ENSMUST00000005923.6
Psmb4
proteasome (prosome, macropain) subunit, beta type 4
chr11_+_115765420 0.309 ENSMUST00000093912.4
ENSMUST00000136720.1
ENSMUST00000103034.3
ENSMUST00000141871.1
2310067B10Rik



RIKEN cDNA 2310067B10 gene



chr9_-_50528641 0.294 ENSMUST00000034570.5
Pts
6-pyruvoyl-tetrahydropterin synthase
chr7_+_27731398 0.282 ENSMUST00000130997.1
Zfp60
zinc finger protein 60
chr3_+_55140033 0.269 ENSMUST00000118963.2
ENSMUST00000061099.7
ENSMUST00000153009.1
Ccdc169


coiled-coil domain containing 169


chr2_+_85037212 0.267 ENSMUST00000077798.6
Ssrp1
structure specific recognition protein 1
chr14_-_73385225 0.267 ENSMUST00000022704.7
Itm2b
integral membrane protein 2B
chr15_-_76069681 0.265 ENSMUST00000002603.5
ENSMUST00000063747.5
Scrib

scribbled homolog (Drosophila)

chr19_-_43524462 0.262 ENSMUST00000026196.7
Got1
glutamate oxaloacetate transaminase 1, soluble
chr3_+_142594847 0.257 ENSMUST00000029936.4
Gbp2b
guanylate binding protein 2b
chr1_-_136346074 0.251 ENSMUST00000048309.6
Camsap2
calmodulin regulated spectrin-associated protein family, member 2
chr2_+_167062934 0.235 ENSMUST00000125674.1
1500012F01Rik
RIKEN cDNA 1500012F01 gene
chr2_+_72476225 0.233 ENSMUST00000157019.1
Cdca7
cell division cycle associated 7
chr10_+_127759721 0.228 ENSMUST00000073639.5
Rdh1
retinol dehydrogenase 1 (all trans)
chr6_+_81923645 0.221 ENSMUST00000043195.4
Gcfc2
GC-rich sequence DNA binding factor 2
chr13_-_107414742 0.219 ENSMUST00000061241.6
Apoo-ps
apolipoprotein O, pseudogene
chr3_+_95427575 0.217 ENSMUST00000181809.1
Gm4349
predicted gene 4349
chr4_+_12140263 0.217 ENSMUST00000050069.2
ENSMUST00000069128.7
Rbm12b1

RNA binding motif protein 12 B1

chr16_+_58670208 0.202 ENSMUST00000060077.5
Cpox
coproporphyrinogen oxidase
chr11_+_101552135 0.199 ENSMUST00000103099.1
Nbr1
neighbor of Brca1 gene 1
chr12_-_113307912 0.196 ENSMUST00000103418.1
Ighg2b
immunoglobulin heavy constant gamma 2B
chr13_-_67332525 0.186 ENSMUST00000168892.1
ENSMUST00000109735.2
Zfp595

zinc finger protein 595

chr2_-_37359196 0.185 ENSMUST00000147703.1
Pdcl
phosducin-like
chr7_-_15627876 0.182 ENSMUST00000086122.3
ENSMUST00000174443.1
Obox3

oocyte specific homeobox 3

chr5_+_88583527 0.176 ENSMUST00000031229.6
Rufy3
RUN and FYVE domain containing 3
chr2_+_11642786 0.170 ENSMUST00000028111.4
Il2ra
interleukin 2 receptor, alpha chain
chr1_-_33814516 0.156 ENSMUST00000044455.5
ENSMUST00000115167.1
Zfp451

zinc finger protein 451

chr18_+_7869707 0.153 ENSMUST00000166062.1
ENSMUST00000169010.1
Wac

WW domain containing adaptor with coiled-coil

chrX_+_166238901 0.151 ENSMUST00000112235.1
Gpm6b
glycoprotein m6b
chr6_+_58833689 0.142 ENSMUST00000041401.8
Herc3
hect domain and RLD 3
chr2_-_79908428 0.138 ENSMUST00000102652.3
ENSMUST00000102651.3
Pde1a

phosphodiesterase 1A, calmodulin-dependent

chr4_+_149545102 0.129 ENSMUST00000105692.1
Ctnnbip1
catenin beta interacting protein 1
chrM_+_5319 0.124 ENSMUST00000082402.1
mt-Co1
mitochondrially encoded cytochrome c oxidase I
chr19_-_29753600 0.120 ENSMUST00000175764.1
9930021J03Rik
RIKEN cDNA 9930021J03 gene
chr3_+_89136572 0.118 ENSMUST00000107482.3
ENSMUST00000127058.1
Pklr

pyruvate kinase liver and red blood cell

chr11_+_87853207 0.118 ENSMUST00000038196.6
Mks1
Meckel syndrome, type 1
chr13_+_13954614 0.107 ENSMUST00000099747.3
B3galnt2
UDP-GalNAc:betaGlcNAc beta 1,3-galactosaminyltransferase, polypeptide 2
chr10_+_127759780 0.106 ENSMUST00000128247.1
RP23-386P10.11
Protein Rdh9
chr12_+_4817545 0.104 ENSMUST00000046207.7
0610009D07Rik
RIKEN cDNA 0610009D07 gene
chr6_+_137735078 0.101 ENSMUST00000064910.6
Strap
serine/threonine kinase receptor associated protein
chr2_+_85037448 0.100 ENSMUST00000168266.1
ENSMUST00000130729.1
Ssrp1

structure specific recognition protein 1

chr4_+_126677630 0.093 ENSMUST00000030642.2
Psmb2
proteasome (prosome, macropain) subunit, beta type 2
chr1_+_127729405 0.085 ENSMUST00000038006.6
Acmsd
amino carboxymuconate semialdehyde decarboxylase
chr1_-_85270543 0.084 ENSMUST00000093506.5
ENSMUST00000064341.8
C130026I21Rik

RIKEN cDNA C130026I21 gene

chr11_+_58948890 0.074 ENSMUST00000078267.3
Hist3h2ba
histone cluster 3, H2ba
chr13_-_62777089 0.061 ENSMUST00000167516.2
Gm5141
predicted gene 5141
chr6_+_122707489 0.057 ENSMUST00000112581.1
ENSMUST00000112580.1
ENSMUST00000012540.4
Nanog


Nanog homeobox


chr8_-_3467617 0.052 ENSMUST00000111081.3
ENSMUST00000118194.1
ENSMUST00000004686.6
Pex11g


peroxisomal biogenesis factor 11 gamma


chr5_+_42067960 0.044 ENSMUST00000087332.4
Gm16223
predicted gene 16223
chr18_+_7869159 0.043 ENSMUST00000170932.1
ENSMUST00000167020.1
Wac

WW domain containing adaptor with coiled-coil

chr7_-_121074501 0.041 ENSMUST00000047194.2
Igsf6
immunoglobulin superfamily, member 6
chr9_+_50494516 0.032 ENSMUST00000114474.1
1600029D21Rik
RIKEN cDNA 1600029D21 gene
chr2_-_79908389 0.031 ENSMUST00000090756.4
Pde1a
phosphodiesterase 1A, calmodulin-dependent
chr8_-_11678728 0.015 ENSMUST00000033906.4
1700016D06Rik
RIKEN cDNA 1700016D06 gene
chr3_-_151762906 0.009 ENSMUST00000046739.4
Ifi44l
interferon-induced protein 44 like
chr7_+_103550368 0.005 ENSMUST00000106888.1
Olfr613
olfactory receptor 613

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
3.2 15.9 GO:0015671 oxygen transport(GO:0015671)
0.7 3.7 GO:1903215 negative regulation of protein targeting to mitochondrion(GO:1903215)
0.6 1.8 GO:0060023 soft palate development(GO:0060023)
0.6 1.8 GO:2000620 positive regulation of histone H4-K16 acetylation(GO:2000620)
0.4 2.0 GO:0060849 regulation of transcription involved in lymphatic endothelial cell fate commitment(GO:0060849)
0.3 0.9 GO:1902605 heterotrimeric G-protein complex assembly(GO:1902605)
0.2 0.6 GO:0006436 tryptophanyl-tRNA aminoacylation(GO:0006436)
0.2 0.6 GO:0046462 monoacylglycerol metabolic process(GO:0046462)
0.2 8.1 GO:0003301 physiological muscle hypertrophy(GO:0003298) physiological cardiac muscle hypertrophy(GO:0003301) cell growth involved in cardiac muscle cell development(GO:0061049)
0.2 1.0 GO:0035878 nail development(GO:0035878)
0.1 0.4 GO:0001830 trophectodermal cell fate commitment(GO:0001830)
0.1 0.7 GO:0032229 positive regulation of gamma-aminobutyric acid secretion(GO:0014054) negative regulation of synaptic transmission, GABAergic(GO:0032229)
0.1 2.7 GO:0045663 positive regulation of myoblast differentiation(GO:0045663)
0.1 1.3 GO:0006517 protein deglycosylation(GO:0006517)
0.1 0.3 GO:0098968 neurotransmitter receptor transport postsynaptic membrane to endosome(GO:0098968)
0.1 0.3 GO:0006106 fumarate metabolic process(GO:0006106) aspartate biosynthetic process(GO:0006532) aspartate catabolic process(GO:0006533)
0.1 0.9 GO:0090527 actin filament reorganization(GO:0090527)
0.1 0.9 GO:0071763 nuclear membrane organization(GO:0071763)
0.1 1.1 GO:0071257 cellular response to electrical stimulus(GO:0071257)
0.1 0.5 GO:0061368 maternal process involved in parturition(GO:0060137) behavioral response to chemical pain(GO:0061366) behavioral response to formalin induced pain(GO:0061368)
0.1 0.6 GO:0034242 negative regulation of syncytium formation by plasma membrane fusion(GO:0034242)
0.1 0.1 GO:0060633 negative regulation of transcription initiation from RNA polymerase II promoter(GO:0060633) negative regulation of DNA-templated transcription, initiation(GO:2000143)
0.1 0.6 GO:0006682 galactosylceramide biosynthetic process(GO:0006682) galactolipid biosynthetic process(GO:0019375)
0.1 0.1 GO:2000095 regulation of Wnt signaling pathway, planar cell polarity pathway(GO:2000095)
0.1 0.6 GO:0032693 negative regulation of interleukin-10 production(GO:0032693)
0.1 0.5 GO:0061343 cell adhesion involved in heart morphogenesis(GO:0061343)
0.1 0.4 GO:0070814 hydrogen sulfide biosynthetic process(GO:0070814)
0.1 0.2 GO:2000616 negative regulation of histone H3-K9 acetylation(GO:2000616)
0.1 0.7 GO:0046485 ether lipid metabolic process(GO:0046485)
0.0 0.2 GO:0016068 regulation of type I hypersensitivity(GO:0001810) positive regulation of type I hypersensitivity(GO:0001812) type I hypersensitivity(GO:0016068)
0.0 0.3 GO:0002862 negative regulation of inflammatory response to antigenic stimulus(GO:0002862)
0.0 0.3 GO:0042985 negative regulation of amyloid precursor protein biosynthetic process(GO:0042985)
0.0 1.1 GO:1902043 positive regulation of extrinsic apoptotic signaling pathway via death domain receptors(GO:1902043)
0.0 0.2 GO:0046013 regulation of T cell homeostatic proliferation(GO:0046013)
0.0 0.2 GO:0046501 protoporphyrinogen IX metabolic process(GO:0046501)
0.0 0.6 GO:0035970 peptidyl-threonine dephosphorylation(GO:0035970)
0.0 0.3 GO:0006729 tetrahydrobiopterin biosynthetic process(GO:0006729) tetrahydrobiopterin metabolic process(GO:0046146)
0.0 0.3 GO:0051490 negative regulation of filopodium assembly(GO:0051490)
0.0 0.8 GO:0015813 L-glutamate transport(GO:0015813)
0.0 0.1 GO:0019805 quinolinate biosynthetic process(GO:0019805)
0.0 0.1 GO:0019276 UDP-N-acetylgalactosamine metabolic process(GO:0019276)
0.0 1.1 GO:0042491 auditory receptor cell differentiation(GO:0042491)
0.0 3.7 GO:0030177 positive regulation of Wnt signaling pathway(GO:0030177)
0.0 4.9 GO:0060348 bone development(GO:0060348)
0.0 0.5 GO:0045742 positive regulation of epidermal growth factor receptor signaling pathway(GO:0045742) positive regulation of ERBB signaling pathway(GO:1901186)
0.0 0.2 GO:0051611 negative regulation of neurotransmitter uptake(GO:0051581) serotonin uptake(GO:0051610) regulation of serotonin uptake(GO:0051611) negative regulation of serotonin uptake(GO:0051612)
0.0 0.9 GO:0000184 nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:0000184)
0.0 0.1 GO:0030277 maintenance of gastrointestinal epithelium(GO:0030277)
0.0 0.1 GO:0042866 pyruvate biosynthetic process(GO:0042866)
0.0 0.1 GO:1903225 regulation of endodermal cell fate specification(GO:0042663) negative regulation of endodermal cell differentiation(GO:1903225)
0.0 0.1 GO:0071894 histone H2B conserved C-terminal lysine ubiquitination(GO:0071894)
0.0 0.6 GO:0045494 photoreceptor cell maintenance(GO:0045494)
0.0 0.3 GO:0044406 adhesion of symbiont to host(GO:0044406)
0.0 0.2 GO:0034390 smooth muscle cell apoptotic process(GO:0034390) regulation of smooth muscle cell apoptotic process(GO:0034391)
0.0 0.8 GO:0045773 positive regulation of axon extension(GO:0045773)
0.0 0.5 GO:1902653 cholesterol biosynthetic process(GO:0006695) secondary alcohol biosynthetic process(GO:1902653)
0.0 0.1 GO:0006123 mitochondrial electron transport, cytochrome c to oxygen(GO:0006123)
0.0 0.9 GO:0006672 ceramide metabolic process(GO:0006672)
0.0 0.1 GO:0031468 nuclear envelope reassembly(GO:0031468)
0.0 0.5 GO:0006506 GPI anchor biosynthetic process(GO:0006506)
0.0 1.9 GO:0051291 protein heterooligomerization(GO:0051291)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
1.6 12.7 GO:0005833 hemoglobin complex(GO:0005833)
0.3 1.8 GO:0070531 BRCA1-A complex(GO:0070531)
0.1 0.7 GO:0032983 kainate selective glutamate receptor complex(GO:0032983)
0.1 1.0 GO:0030056 hemidesmosome(GO:0030056)
0.1 1.4 GO:0005614 interstitial matrix(GO:0005614)
0.1 0.2 GO:0071008 U2-type post-mRNA release spliceosomal complex(GO:0071008)
0.1 0.3 GO:0034750 Scrib-APC-beta-catenin complex(GO:0034750)
0.1 0.3 GO:0036449 microtubule minus-end(GO:0036449)
0.0 2.7 GO:0044295 axonal growth cone(GO:0044295)
0.0 0.7 GO:0036038 MKS complex(GO:0036038)
0.0 1.1 GO:0045334 clathrin-coated endocytic vesicle(GO:0045334)
0.0 1.0 GO:0005689 U12-type spliceosomal complex(GO:0005689)
0.0 0.3 GO:1990635 proximal dendrite(GO:1990635)
0.0 0.9 GO:0035145 exon-exon junction complex(GO:0035145)
0.0 0.3 GO:0020005 symbiont-containing vacuole membrane(GO:0020005)
0.0 0.4 GO:0016327 apicolateral plasma membrane(GO:0016327)
0.0 6.9 GO:0014069 postsynaptic density(GO:0014069)
0.0 0.2 GO:0042571 immunoglobulin complex, circulating(GO:0042571)
0.0 0.4 GO:0005839 proteasome core complex(GO:0005839)
0.0 1.1 GO:0005871 kinesin complex(GO:0005871)
0.0 0.1 GO:0030877 beta-catenin destruction complex(GO:0030877)
0.0 0.1 GO:0034719 SMN complex(GO:0032797) SMN-Sm protein complex(GO:0034719)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
3.2 15.9 GO:0005344 oxygen transporter activity(GO:0005344)
0.3 0.9 GO:0001729 ceramide kinase activity(GO:0001729)
0.2 0.6 GO:0004830 tryptophan-tRNA ligase activity(GO:0004830)
0.2 1.0 GO:0004032 alditol:NADP+ 1-oxidoreductase activity(GO:0004032)
0.2 1.0 GO:0038132 neuregulin binding(GO:0038132)
0.2 0.6 GO:0003846 2-acylglycerol O-acyltransferase activity(GO:0003846)
0.2 0.5 GO:0004769 steroid delta-isomerase activity(GO:0004769)
0.2 0.9 GO:0008479 queuine tRNA-ribosyltransferase activity(GO:0008479)
0.2 2.0 GO:0001972 retinoic acid binding(GO:0001972)
0.1 0.6 GO:0047275 glucosaminylgalactosylglucosylceramide beta-galactosyltransferase activity(GO:0047275)
0.1 0.7 GO:0016803 ether hydrolase activity(GO:0016803)
0.1 0.7 GO:0015277 kainate selective glutamate receptor activity(GO:0015277)
0.1 1.7 GO:0016805 dipeptidase activity(GO:0016805)
0.1 1.0 GO:0097157 pre-mRNA intronic binding(GO:0097157)
0.1 0.3 GO:0004069 L-aspartate:2-oxoglutarate aminotransferase activity(GO:0004069)
0.1 0.3 GO:0019002 GMP binding(GO:0019002)
0.1 0.5 GO:0017040 ceramidase activity(GO:0017040)
0.1 0.8 GO:0005314 high-affinity glutamate transmembrane transporter activity(GO:0005314)
0.1 0.3 GO:0004385 guanylate kinase activity(GO:0004385)
0.0 0.1 GO:0004743 pyruvate kinase activity(GO:0004743)
0.0 0.7 GO:0030553 cGMP binding(GO:0030553)
0.0 0.9 GO:0005521 lamin binding(GO:0005521)
0.0 1.8 GO:0001105 RNA polymerase II transcription coactivator activity(GO:0001105)
0.0 0.5 GO:0045499 chemorepellent activity(GO:0045499)
0.0 1.8 GO:0003684 damaged DNA binding(GO:0003684)
0.0 0.3 GO:0051011 microtubule minus-end binding(GO:0051011)
0.0 0.5 GO:0000030 mannosyltransferase activity(GO:0000030)
0.0 0.2 GO:0005212 structural constituent of eye lens(GO:0005212)
0.0 0.2 GO:0061665 SUMO ligase activity(GO:0061665)
0.0 0.2 GO:0004745 retinol dehydrogenase activity(GO:0004745)
0.0 1.3 GO:0043621 protein self-association(GO:0043621)
0.0 0.4 GO:0004298 threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
0.0 0.6 GO:0050699 WW domain binding(GO:0050699)
0.0 0.5 GO:0030676 Rac guanyl-nucleotide exchange factor activity(GO:0030676)
0.0 5.3 GO:0005096 GTPase activator activity(GO:0005096)
0.0 2.2 GO:0003774 motor activity(GO:0003774)
0.0 0.4 GO:0071837 HMG box domain binding(GO:0071837)
0.0 0.2 GO:0034987 immunoglobulin receptor binding(GO:0034987)
0.0 0.1 GO:0001010 transcription factor activity, sequence-specific DNA binding transcription factor recruiting(GO:0001010)
0.0 0.5 GO:0048365 Rac GTPase binding(GO:0048365)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.0 PID_INTEGRIN4_PATHWAY Alpha6 beta4 integrin-ligand interactions
0.1 2.5 PID_HEDGEHOG_2PATHWAY Signaling events mediated by the Hedgehog family
0.1 3.8 PID_HNF3A_PATHWAY FOXA1 transcription factor network
0.0 0.5 PID_CONE_PATHWAY Visual signal transduction: Cones
0.0 0.9 ST_GRANULE_CELL_SURVIVAL_PATHWAY Granule Cell Survival Pathway is a specific case of more general PAC1 Receptor Pathway.
0.0 1.1 PID_ECADHERIN_STABILIZATION_PATHWAY Stabilization and expansion of the E-cadherin adherens junction
0.0 0.6 NABA_PROTEOGLYCANS Genes encoding proteoglycans
0.0 0.3 PID_ARF6_DOWNSTREAM_PATHWAY Arf6 downstream pathway

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.8 REACTOME_HOMOLOGOUS_RECOMBINATION_REPAIR_OF_REPLICATION_INDEPENDENT_DOUBLE_STRAND_BREAKS Genes involved in Homologous recombination repair of replication-independent double-strand breaks
0.1 2.7 REACTOME_MYOGENESIS Genes involved in Myogenesis
0.0 1.1 REACTOME_KINESINS Genes involved in Kinesins
0.0 0.7 REACTOME_IONOTROPIC_ACTIVITY_OF_KAINATE_RECEPTORS Genes involved in Ionotropic activity of Kainate Receptors
0.0 6.1 REACTOME_SIGNALING_BY_RHO_GTPASES Genes involved in Signaling by Rho GTPases
0.0 1.1 REACTOME_TRAFFICKING_OF_AMPA_RECEPTORS Genes involved in Trafficking of AMPA receptors
0.0 0.5 REACTOME_CHOLESTEROL_BIOSYNTHESIS Genes involved in Cholesterol biosynthesis
0.0 2.0 REACTOME_TRANSCRIPTIONAL_REGULATION_OF_WHITE_ADIPOCYTE_DIFFERENTIATION Genes involved in Transcriptional Regulation of White Adipocyte Differentiation
0.0 0.6 REACTOME_CYTOSOLIC_TRNA_AMINOACYLATION Genes involved in Cytosolic tRNA aminoacylation
0.0 0.7 REACTOME_GLYCOSPHINGOLIPID_METABOLISM Genes involved in Glycosphingolipid metabolism
0.0 0.9 REACTOME_MRNA_3_END_PROCESSING Genes involved in mRNA 3'-end processing
0.0 0.5 REACTOME_SYNTHESIS_OF_GLYCOSYLPHOSPHATIDYLINOSITOL_GPI Genes involved in Synthesis of glycosylphosphatidylinositol (GPI)
0.0 0.3 REACTOME_METABOLISM_OF_POLYAMINES Genes involved in Metabolism of polyamines
0.0 0.4 REACTOME_ELONGATION_ARREST_AND_RECOVERY Genes involved in Elongation arrest and recovery
0.0 0.4 REACTOME_SMAD2_SMAD3_SMAD4_HETEROTRIMER_REGULATES_TRANSCRIPTION Genes involved in SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription