Motif ID: Gata6

Z-value: 0.256


Transcription factors associated with Gata6:

Gene SymbolEntrez IDGene Name
Gata6 ENSMUSG00000005836.8 Gata6



Activity profile for motif Gata6.

activity profile for motif Gata6


Sorted Z-values histogram for motif Gata6

Sorted Z-values for motif Gata6



Network of associatons between targets according to the STRING database.



First level regulatory network of Gata6

PNG image of the network

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Top targets:


Showing 1 to 20 of 69 entries
PromoterScoreRefseqGene SymbolGene Name
chr7_-_103853199 1.396 ENSMUST00000033229.3
Hbb-y
hemoglobin Y, beta-like embryonic chain
chr6_-_23248264 1.289 ENSMUST00000031709.5
Fezf1
Fez family zinc finger 1
chr8_+_45628176 0.870 ENSMUST00000130850.1
Sorbs2
sorbin and SH3 domain containing 2
chr8_+_45627946 0.780 ENSMUST00000145458.1
Sorbs2
sorbin and SH3 domain containing 2
chr8_+_45627709 0.732 ENSMUST00000134321.1
ENSMUST00000135336.1
Sorbs2

sorbin and SH3 domain containing 2

chr4_+_13751297 0.595 ENSMUST00000105566.2
Runx1t1
runt-related transcription factor 1; translocated to, 1 (cyclin D-related)
chr8_-_122699066 0.439 ENSMUST00000127984.1
Cbfa2t3
core-binding factor, runt domain, alpha subunit 2, translocated to, 3 (human)
chr12_+_95692212 0.420 ENSMUST00000057324.3
Flrt2
fibronectin leucine rich transmembrane protein 2
chr16_-_46010212 0.351 ENSMUST00000130481.1
Plcxd2
phosphatidylinositol-specific phospholipase C, X domain containing 2
chr2_+_65930117 0.347 ENSMUST00000176109.1
Csrnp3
cysteine-serine-rich nuclear protein 3
chr1_+_179803376 0.342 ENSMUST00000097454.2
Gm10518
predicted gene 10518
chr5_-_73191848 0.310 ENSMUST00000176910.1
Fryl
furry homolog-like (Drosophila)
chr1_-_25829511 0.280 ENSMUST00000135518.1
ENSMUST00000151309.1
Bai3

brain-specific angiogenesis inhibitor 3

chr2_+_80617045 0.277 ENSMUST00000028384.4
Dusp19
dual specificity phosphatase 19
chr2_+_71786923 0.270 ENSMUST00000112101.1
ENSMUST00000028522.3
Itga6

integrin alpha 6

chr16_-_34262945 0.255 ENSMUST00000114953.1
Kalrn
kalirin, RhoGEF kinase
chr9_+_66350465 0.250 ENSMUST00000042824.6
Herc1
hect (homologous to the E6-AP (UBE3A) carboxyl terminus) domain and RCC1 (CHC1)-like domain (RLD) 1
chr4_-_110287479 0.247 ENSMUST00000106598.1
ENSMUST00000102723.4
ENSMUST00000153906.1
Elavl4


ELAV (embryonic lethal, abnormal vision, Drosophila)-like 4 (Hu antigen D)


chr2_-_172370506 0.247 ENSMUST00000109139.1
ENSMUST00000028997.7
ENSMUST00000109140.3
Aurka


aurora kinase A


chr6_-_127109517 0.241 ENSMUST00000039913.8
9630033F20Rik
RIKEN cDNA 9630033F20 gene

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 20 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 2.4 GO:0003301 physiological muscle hypertrophy(GO:0003298) physiological cardiac muscle hypertrophy(GO:0003301) cell growth involved in cardiac muscle cell development(GO:0061049)
0.3 1.4 GO:0015671 oxygen transport(GO:0015671)
0.2 1.3 GO:0021797 forebrain anterior/posterior pattern specification(GO:0021797)
0.0 0.6 GO:0021692 cerebellar Purkinje cell layer morphogenesis(GO:0021692)
0.0 0.6 GO:0045599 negative regulation of fat cell differentiation(GO:0045599)
0.1 0.4 GO:1903715 regulation of aerobic respiration(GO:1903715)
0.0 0.4 GO:0061343 cell adhesion involved in heart morphogenesis(GO:0061343)
0.0 0.3 GO:0035878 nail development(GO:0035878)
0.0 0.3 GO:0061368 maternal process involved in parturition(GO:0060137) behavioral response to chemical pain(GO:0061366) behavioral response to formalin induced pain(GO:0061368)
0.0 0.3 GO:0090527 actin filament reorganization(GO:0090527)
0.0 0.3 GO:0000188 inactivation of MAPK activity(GO:0000188)
0.1 0.2 GO:0007056 spindle assembly involved in female meiosis(GO:0007056) positive regulation of oocyte development(GO:0060282)
0.0 0.2 GO:1903298 regulation of hypoxia-induced intrinsic apoptotic signaling pathway(GO:1903297) negative regulation of hypoxia-induced intrinsic apoptotic signaling pathway(GO:1903298)
0.0 0.2 GO:0006012 galactose metabolic process(GO:0006012)
0.0 0.2 GO:0006654 phosphatidic acid biosynthetic process(GO:0006654)
0.0 0.1 GO:0030043 actin filament fragmentation(GO:0030043)
0.0 0.1 GO:1990416 positive regulation of neurotrophin TRK receptor signaling pathway(GO:0051388) cellular response to brain-derived neurotrophic factor stimulus(GO:1990416)
0.0 0.1 GO:0006682 galactosylceramide biosynthetic process(GO:0006682) galactolipid biosynthetic process(GO:0019375)
0.0 0.1 GO:0034242 negative regulation of syncytium formation by plasma membrane fusion(GO:0034242)
0.0 0.0 GO:0030208 dermatan sulfate biosynthetic process(GO:0030208)

Gene overrepresentation in cellular_component category:

Showing 1 to 10 of 10 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.2 1.4 GO:0005833 hemoglobin complex(GO:0005833)
0.0 0.3 GO:0030056 hemidesmosome(GO:0030056)
0.1 0.2 GO:0042585 germinal vesicle(GO:0042585)
0.0 0.2 GO:0042788 polysomal ribosome(GO:0042788)
0.0 0.2 GO:0008290 F-actin capping protein complex(GO:0008290)
0.0 0.2 GO:0034663 endoplasmic reticulum chaperone complex(GO:0034663)
0.0 0.1 GO:0008091 spectrin(GO:0008091)
0.0 0.1 GO:0001674 female germ cell nucleus(GO:0001674)
0.0 0.1 GO:0008541 proteasome regulatory particle, lid subcomplex(GO:0008541)
0.0 0.1 GO:0000220 vacuolar proton-transporting V-type ATPase, V0 domain(GO:0000220)

Gene overrepresentation in molecular_function category:

Showing 1 to 12 of 12 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.3 1.4 GO:0031721 hemoglobin alpha binding(GO:0031721)
0.0 0.4 GO:0045499 chemorepellent activity(GO:0045499)
0.1 0.3 GO:0008330 protein tyrosine/threonine phosphatase activity(GO:0008330)
0.1 0.3 GO:0038132 neuregulin binding(GO:0038132)
0.1 0.2 GO:0004335 galactokinase activity(GO:0004335)
0.1 0.2 GO:0008195 phosphatidate phosphatase activity(GO:0008195)
0.0 0.2 GO:0035174 histone serine kinase activity(GO:0035174)
0.0 0.2 GO:0050692 DBD domain binding(GO:0050692)
0.0 0.1 GO:0047275 glucosaminylgalactosylglucosylceramide beta-galactosyltransferase activity(GO:0047275)
0.0 0.1 GO:0015129 lactate transmembrane transporter activity(GO:0015129)
0.0 0.1 GO:0061133 endopeptidase activator activity(GO:0061133)
0.0 0.1 GO:0005212 structural constituent of eye lens(GO:0005212)

Gene overrepresentation in C2:CP category:

Showing 1 to 1 of 1 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 0.3 PID_INTEGRIN4_PATHWAY Alpha6 beta4 integrin-ligand interactions

Gene overrepresentation in C2:CP:REACTOME category:

Showing 1 to 1 of 1 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 0.2 REACTOME_SYNTHESIS_OF_PE Genes involved in Synthesis of PE