Motif ID: Gli1

Z-value: 0.856


Transcription factors associated with Gli1:

Gene SymbolEntrez IDGene Name
Gli1 ENSMUSG00000025407.6 Gli1

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Gli1mm10_v2_chr10_-_127341583_127341614-0.616.4e-05Click!


Activity profile for motif Gli1.

activity profile for motif Gli1


Sorted Z-values histogram for motif Gli1

Sorted Z-values for motif Gli1



Network of associatons between targets according to the STRING database.



First level regulatory network of Gli1

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr10_-_64090241 4.291 ENSMUST00000133588.1
Lrrtm3
leucine rich repeat transmembrane neuronal 3
chr10_-_64090265 4.192 ENSMUST00000105439.1
Lrrtm3
leucine rich repeat transmembrane neuronal 3
chr12_-_81333129 3.129 ENSMUST00000085238.6
ENSMUST00000182208.1
Slc8a3

solute carrier family 8 (sodium/calcium exchanger), member 3

chr2_-_54085542 2.915 ENSMUST00000100089.2
Rprm
reprimo, TP53 dependent G2 arrest mediator candidate
chr4_-_68954351 2.687 ENSMUST00000030036.5
Brinp1
bone morphogenic protein/retinoic acid inducible neural specific 1
chr15_-_95528228 2.664 ENSMUST00000075275.2
Nell2
NEL-like 2
chr2_+_118111876 2.661 ENSMUST00000039559.8
Thbs1
thrombospondin 1
chr6_-_52012476 2.532 ENSMUST00000078214.5
Skap2
src family associated phosphoprotein 2
chr15_-_85581809 2.471 ENSMUST00000023015.7
Wnt7b
wingless-related MMTV integration site 7B
chr13_+_118714678 2.456 ENSMUST00000022246.8
Fgf10
fibroblast growth factor 10
chr13_-_114458720 2.390 ENSMUST00000022287.5
Fst
follistatin
chr15_-_95528702 2.361 ENSMUST00000166170.1
Nell2
NEL-like 2
chr5_+_30588078 2.291 ENSMUST00000066295.2
Kcnk3
potassium channel, subfamily K, member 3
chr11_-_119547744 2.180 ENSMUST00000026670.4
Nptx1
neuronal pentraxin 1
chr12_+_44328882 2.133 ENSMUST00000020939.8
ENSMUST00000110748.2
Nrcam

neuron-glia-CAM-related cell adhesion molecule

chr3_+_68494208 2.016 ENSMUST00000182719.1
Schip1
schwannomin interacting protein 1
chr8_+_54954728 1.917 ENSMUST00000033915.7
Gpm6a
glycoprotein m6a
chr1_-_56972437 1.892 ENSMUST00000042857.7
Satb2
special AT-rich sequence binding protein 2
chr5_+_5573952 1.856 ENSMUST00000101627.2
Gm8773
predicted gene 8773
chr15_-_78544345 1.755 ENSMUST00000053239.2
Sstr3
somatostatin receptor 3
chr18_-_43373248 1.733 ENSMUST00000118043.1
Dpysl3
dihydropyrimidinase-like 3
chr13_+_109685994 1.616 ENSMUST00000074103.5
Pde4d
phosphodiesterase 4D, cAMP specific
chr6_-_28830345 1.599 ENSMUST00000171353.1
Lrrc4
leucine rich repeat containing 4
chr1_-_25228814 1.542 ENSMUST00000126626.1
Bai3
brain-specific angiogenesis inhibitor 3
chr13_+_5861489 1.519 ENSMUST00000000080.6
Klf6
Kruppel-like factor 6
chr6_+_108213086 1.452 ENSMUST00000032192.6
Itpr1
inositol 1,4,5-trisphosphate receptor 1
chr7_+_73391160 1.436 ENSMUST00000128471.1
Rgma
RGM domain family, member A
chr6_+_107529717 1.349 ENSMUST00000049285.8
Lrrn1
leucine rich repeat protein 1, neuronal
chr2_-_92434027 1.272 ENSMUST00000111278.1
ENSMUST00000090559.5
Cry2

cryptochrome 2 (photolyase-like)

chr1_+_72824482 1.254 ENSMUST00000047328.4
Igfbp2
insulin-like growth factor binding protein 2
chr10_+_69534039 1.249 ENSMUST00000182557.1
Ank3
ankyrin 3, epithelial
chr17_-_24209377 1.212 ENSMUST00000024931.4
Ntn3
netrin 3
chr4_+_106561027 1.129 ENSMUST00000047973.3
Dhcr24
24-dehydrocholesterol reductase
chrX_+_101299143 1.128 ENSMUST00000118111.1
ENSMUST00000130555.1
ENSMUST00000151528.1
Nlgn3


neuroligin 3


chr17_+_34187545 1.119 ENSMUST00000170086.1
Tap1
transporter 1, ATP-binding cassette, sub-family B (MDR/TAP)
chr1_+_152954966 1.094 ENSMUST00000043313.8
Nmnat2
nicotinamide nucleotide adenylyltransferase 2
chrX_+_159303266 1.063 ENSMUST00000112491.1
Rps6ka3
ribosomal protein S6 kinase polypeptide 3
chr2_-_30801698 1.046 ENSMUST00000050003.8
1700001O22Rik
RIKEN cDNA 1700001O22 gene
chr10_+_40883819 1.041 ENSMUST00000105509.1
Wasf1
WAS protein family, member 1
chr13_-_117025505 1.017 ENSMUST00000022239.6
Parp8
poly (ADP-ribose) polymerase family, member 8
chr4_-_58553311 0.996 ENSMUST00000107571.1
ENSMUST00000055018.4
Lpar1

lysophosphatidic acid receptor 1

chr1_-_133801031 0.980 ENSMUST00000143567.1
Atp2b4
ATPase, Ca++ transporting, plasma membrane 4
chr5_-_32746317 0.953 ENSMUST00000135248.1
Pisd
phosphatidylserine decarboxylase
chr14_+_25607797 0.945 ENSMUST00000160229.1
Zmiz1
zinc finger, MIZ-type containing 1
chr17_+_34187789 0.936 ENSMUST00000041633.8
Tap1
transporter 1, ATP-binding cassette, sub-family B (MDR/TAP)
chr2_+_20737306 0.918 ENSMUST00000114606.1
ENSMUST00000114608.1
Etl4

enhancer trap locus 4

chr1_-_64121389 0.915 ENSMUST00000055001.3
Klf7
Kruppel-like factor 7 (ubiquitous)
chr4_-_58553553 0.896 ENSMUST00000107575.2
ENSMUST00000107574.1
ENSMUST00000147354.1
Lpar1


lysophosphatidic acid receptor 1


chr8_-_64733534 0.876 ENSMUST00000141021.1
Sc4mol
sterol-C4-methyl oxidase-like
chr2_-_93046053 0.870 ENSMUST00000111272.1
ENSMUST00000178666.1
ENSMUST00000147339.1
Prdm11


PR domain containing 11


chrX_-_60893430 0.858 ENSMUST00000135107.2
Sox3
SRY-box containing gene 3
chr10_+_69534208 0.840 ENSMUST00000182439.1
ENSMUST00000092434.5
ENSMUST00000092432.5
ENSMUST00000092431.5
ENSMUST00000054167.8
ENSMUST00000047061.6
Ank3





ankyrin 3, epithelial





chr10_-_63421739 0.825 ENSMUST00000054760.4
Gm7075
predicted gene 7075
chr4_-_58553184 0.820 ENSMUST00000145361.1
Lpar1
lysophosphatidic acid receptor 1
chr9_+_45954101 0.813 ENSMUST00000181487.1
A830035O19Rik
RIKEN cDNA A830035O19 gene
chrX_+_101299207 0.809 ENSMUST00000065858.2
Nlgn3
neuroligin 3
chrX_+_155262443 0.797 ENSMUST00000026324.9
Acot9
acyl-CoA thioesterase 9
chr3_+_45378396 0.793 ENSMUST00000166126.1
ENSMUST00000170695.1
ENSMUST00000171554.1
Pcdh10


protocadherin 10


chr2_+_119351222 0.787 ENSMUST00000028780.3
Chac1
ChaC, cation transport regulator 1
chrX_-_59567348 0.786 ENSMUST00000124402.1
Fgf13
fibroblast growth factor 13
chr16_-_91011029 0.785 ENSMUST00000130813.1
Synj1
synaptojanin 1
chr11_-_42182163 0.768 ENSMUST00000153147.1
Gabra1
gamma-aminobutyric acid (GABA) A receptor, subunit alpha 1
chr14_-_41008256 0.753 ENSMUST00000136661.1
Fam213a
family with sequence similarity 213, member A
chr10_+_69533803 0.697 ENSMUST00000182155.1
ENSMUST00000183169.1
ENSMUST00000183148.1
Ank3


ankyrin 3, epithelial


chrX_-_59568068 0.693 ENSMUST00000119833.1
ENSMUST00000131319.1
Fgf13

fibroblast growth factor 13

chr17_+_37045963 0.690 ENSMUST00000025338.9
Gabbr1
gamma-aminobutyric acid (GABA) B receptor, 1
chr2_+_129800451 0.687 ENSMUST00000165413.2
ENSMUST00000166282.2
Stk35

serine/threonine kinase 35

chr11_-_42000284 0.677 ENSMUST00000109292.2
ENSMUST00000109290.1
Gabrg2

gamma-aminobutyric acid (GABA) A receptor, subunit gamma 2

chr18_-_70141568 0.676 ENSMUST00000121693.1
Rab27b
RAB27b, member RAS oncogene family
chr6_-_113531575 0.650 ENSMUST00000032425.5
Emc3
ER membrane protein complex subunit 3
chr11_+_97840780 0.646 ENSMUST00000054783.4
B230217C12Rik
RIKEN cDNA B230217C12 gene
chr6_+_95117740 0.636 ENSMUST00000032107.7
ENSMUST00000119582.1
Kbtbd8

kelch repeat and BTB (POZ) domain containing 8

chr11_-_42000532 0.613 ENSMUST00000070735.3
Gabrg2
gamma-aminobutyric acid (GABA) A receptor, subunit gamma 2
chr5_-_115300957 0.611 ENSMUST00000009157.3
Dynll1
dynein light chain LC8-type 1
chr11_+_80300866 0.606 ENSMUST00000017836.7
Rhbdl3
rhomboid, veinlet-like 3 (Drosophila)
chr5_-_115300912 0.602 ENSMUST00000112090.1
Dynll1
dynein light chain LC8-type 1
chr1_+_153900572 0.595 ENSMUST00000139476.1
Glul
glutamate-ammonia ligase (glutamine synthetase)
chr19_+_55316313 0.584 ENSMUST00000095950.2
Vti1a
vesicle transport through interaction with t-SNAREs 1A
chrX_+_94234594 0.579 ENSMUST00000153900.1
Klhl15
kelch-like 15
chr9_+_50752758 0.575 ENSMUST00000034562.7
Cryab
crystallin, alpha B
chr2_-_103797617 0.562 ENSMUST00000028607.6
Caprin1
cell cycle associated protein 1
chr5_-_32746272 0.535 ENSMUST00000120591.1
Pisd
phosphatidylserine decarboxylase
chr14_+_60378242 0.533 ENSMUST00000022561.6
Amer2
APC membrane recruitment 2
chr18_-_35662180 0.527 ENSMUST00000025209.4
ENSMUST00000096573.2
Spata24

spermatogenesis associated 24

chr4_-_41275091 0.521 ENSMUST00000030143.6
ENSMUST00000108068.1
Ubap2

ubiquitin-associated protein 2

chr2_+_106693185 0.513 ENSMUST00000111063.1
Mpped2
metallophosphoesterase domain containing 2
chr2_+_181520533 0.512 ENSMUST00000108797.1
Dnajc5
DnaJ (Hsp40) homolog, subfamily C, member 5
chr18_+_37355271 0.508 ENSMUST00000051163.1
Pcdhb8
protocadherin beta 8
chr7_-_138397704 0.504 ENSMUST00000160436.1
Tcerg1l
transcription elongation regulator 1-like
chr5_-_122989086 0.495 ENSMUST00000046073.9
Kdm2b
lysine (K)-specific demethylase 2B
chr9_+_104063678 0.484 ENSMUST00000047799.5
Acad11
acyl-Coenzyme A dehydrogenase family, member 11
chr11_-_69920892 0.473 ENSMUST00000152589.1
ENSMUST00000108612.1
ENSMUST00000108611.1
Eif5a


eukaryotic translation initiation factor 5A


chr2_+_119034783 0.468 ENSMUST00000028796.1
Rpusd2
RNA pseudouridylate synthase domain containing 2
chr2_+_29890534 0.466 ENSMUST00000113764.3
Odf2
outer dense fiber of sperm tails 2
chr7_+_141216626 0.460 ENSMUST00000141804.1
ENSMUST00000148975.1
Rassf7

Ras association (RalGDS/AF-6) domain family (N-terminal) member 7

chr5_-_115436508 0.445 ENSMUST00000078701.3
4930430O22Rik
RIKEN cDNA 4930430O22 gene
chr4_-_43454600 0.441 ENSMUST00000098105.3
ENSMUST00000098104.3
ENSMUST00000030179.4
Cd72


CD72 antigen


chr2_-_152830615 0.440 ENSMUST00000146380.1
ENSMUST00000134902.1
ENSMUST00000134357.1
ENSMUST00000109820.3
Bcl2l1



BCL2-like 1



chr17_-_84790517 0.440 ENSMUST00000112308.2
Lrpprc
leucine-rich PPR-motif containing
chr2_-_104493690 0.402 ENSMUST00000111124.1
Hipk3
homeodomain interacting protein kinase 3
chr5_-_122989260 0.389 ENSMUST00000118027.1
Kdm2b
lysine (K)-specific demethylase 2B
chr1_-_153900198 0.387 ENSMUST00000123490.1
5830403L16Rik
RIKEN cDNA 5830403L16 gene
chr6_+_28423539 0.385 ENSMUST00000020717.5
ENSMUST00000169841.1
Arf5

ADP-ribosylation factor 5

chr5_-_146963742 0.383 ENSMUST00000125217.1
ENSMUST00000110564.1
ENSMUST00000066675.3
ENSMUST00000016654.2
ENSMUST00000110566.1
ENSMUST00000140526.1
Mtif3





mitochondrial translational initiation factor 3





chr8_+_70501116 0.369 ENSMUST00000127983.1
Crlf1
cytokine receptor-like factor 1
chr9_-_110117379 0.357 ENSMUST00000111991.2
ENSMUST00000149199.1
ENSMUST00000035056.7
ENSMUST00000148287.1
ENSMUST00000127744.1
Dhx30




DEAH (Asp-Glu-Ala-His) box polypeptide 30




chr2_+_181520485 0.349 ENSMUST00000072334.5
Dnajc5
DnaJ (Hsp40) homolog, subfamily C, member 5
chr15_-_80264276 0.349 ENSMUST00000052499.7
Rps19bp1
ribosomal protein S19 binding protein 1
chr4_-_148130678 0.339 ENSMUST00000030862.4
Draxin
dorsal inhibitory axon guidance protein
chr17_-_57031468 0.334 ENSMUST00000007814.8
Khsrp
KH-type splicing regulatory protein
chr4_-_40948196 0.329 ENSMUST00000030125.4
ENSMUST00000108089.1
Bag1

BCL2-associated athanogene 1

chr4_-_133874682 0.321 ENSMUST00000168974.2
Rps6ka1
ribosomal protein S6 kinase polypeptide 1
chr15_+_99392948 0.319 ENSMUST00000161250.1
ENSMUST00000160635.1
ENSMUST00000161778.1
Tmbim6


transmembrane BAX inhibitor motif containing 6


chr15_-_56694525 0.310 ENSMUST00000050544.7
Has2
hyaluronan synthase 2
chr2_+_29889720 0.298 ENSMUST00000113767.1
Odf2
outer dense fiber of sperm tails 2
chr2_+_157560078 0.298 ENSMUST00000153739.2
ENSMUST00000173595.1
ENSMUST00000109526.1
ENSMUST00000173839.1
ENSMUST00000173041.1
ENSMUST00000173793.1
ENSMUST00000172487.1
ENSMUST00000088484.5
Nnat







neuronatin







chr4_+_108847827 0.270 ENSMUST00000102738.2
Kti12
KTI12 homolog, chromatin associated (S. cerevisiae)
chr11_+_51619731 0.261 ENSMUST00000127405.1
Nhp2
NHP2 ribonucleoprotein
chr16_-_90284412 0.258 ENSMUST00000039280.7
Scaf4
SR-related CTD-associated factor 4
chr2_-_152831112 0.258 ENSMUST00000128172.1
Bcl2l1
BCL2-like 1
chr14_+_19751257 0.249 ENSMUST00000022340.3
Nid2
nidogen 2
chr13_+_54575020 0.240 ENSMUST00000156024.1
Arl10
ADP-ribosylation factor-like 10
chr2_+_29890063 0.237 ENSMUST00000028128.6
Odf2
outer dense fiber of sperm tails 2
chr15_+_99392882 0.230 ENSMUST00000023749.8
Tmbim6
transmembrane BAX inhibitor motif containing 6
chr3_+_88553716 0.229 ENSMUST00000008748.6
Ubqln4
ubiquilin 4
chr11_+_77763246 0.220 ENSMUST00000108375.2
Myo18a
myosin XVIIIA
chr6_+_37870786 0.210 ENSMUST00000120428.1
ENSMUST00000031859.7
Trim24

tripartite motif-containing 24

chr13_-_58385190 0.208 ENSMUST00000022032.5
2210016F16Rik
RIKEN cDNA 2210016F16 gene
chr1_-_191907527 0.207 ENSMUST00000069573.5
1700034H15Rik
RIKEN cDNA 1700034H15 gene
chr4_-_43454582 0.203 ENSMUST00000107925.1
Cd72
CD72 antigen
chr5_-_110779937 0.200 ENSMUST00000112426.1
Pus1
pseudouridine synthase 1
chr19_-_3575708 0.196 ENSMUST00000113997.2
ENSMUST00000025846.8
ENSMUST00000172362.1
Ppp6r3


protein phosphatase 6, regulatory subunit 3


chr13_+_54575008 0.190 ENSMUST00000026988.4
Arl10
ADP-ribosylation factor-like 10
chr2_+_76369967 0.190 ENSMUST00000046389.4
Rbm45
RNA binding motif protein 45
chr4_-_43454563 0.188 ENSMUST00000107926.1
Cd72
CD72 antigen
chr12_-_112673944 0.187 ENSMUST00000130342.1
Akt1
thymoma viral proto-oncogene 1
chr4_+_139193996 0.178 ENSMUST00000030518.9
Capzb
capping protein (actin filament) muscle Z-line, beta
chr2_+_29890096 0.177 ENSMUST00000113762.1
ENSMUST00000113765.1
Odf2

outer dense fiber of sperm tails 2

chr2_-_29253001 0.171 ENSMUST00000071201.4
Ntng2
netrin G2
chr4_+_117096049 0.171 ENSMUST00000030443.5
Ptch2
patched homolog 2
chrX_+_119927196 0.157 ENSMUST00000040961.2
ENSMUST00000113366.1
Pabpc5

poly(A) binding protein, cytoplasmic 5

chr16_-_56024628 0.157 ENSMUST00000119981.1
ENSMUST00000096021.3
Pcnp

PEST proteolytic signal containing nuclear protein

chr9_+_86695542 0.156 ENSMUST00000150367.2
A330041J22Rik
RIKEN cDNA A330041J22 gene
chr12_+_24498570 0.152 ENSMUST00000075954.7
Taf1b
TATA box binding protein (Tbp)-associated factor, RNA polymerase I, B
chr17_+_56326045 0.145 ENSMUST00000139679.1
ENSMUST00000025036.4
ENSMUST00000086835.5
Kdm4b


lysine (K)-specific demethylase 4B


chr5_-_122900267 0.135 ENSMUST00000031435.7
Kdm2b
lysine (K)-specific demethylase 2B
chr7_+_28982832 0.133 ENSMUST00000085835.6
Map4k1
mitogen-activated protein kinase kinase kinase kinase 1
chr4_+_123233556 0.129 ENSMUST00000040821.4
Heyl
hairy/enhancer-of-split related with YRPW motif-like
chr19_-_6084679 0.127 ENSMUST00000161548.1
Zfpl1
zinc finger like protein 1
chr2_+_29889785 0.120 ENSMUST00000113763.1
ENSMUST00000113757.1
ENSMUST00000113756.1
ENSMUST00000133233.1
ENSMUST00000113759.2
ENSMUST00000113755.1
ENSMUST00000137558.1
ENSMUST00000046571.7
Odf2







outer dense fiber of sperm tails 2







chr18_+_37477768 0.116 ENSMUST00000051442.5
Pcdhb16
protocadherin beta 16
chr4_+_74251928 0.112 ENSMUST00000030102.5
Kdm4c
lysine (K)-specific demethylase 4C
chr2_+_85037448 0.107 ENSMUST00000168266.1
ENSMUST00000130729.1
Ssrp1

structure specific recognition protein 1

chr11_-_78245942 0.101 ENSMUST00000002121.4
Supt6
suppressor of Ty 6
chr15_-_100584075 0.097 ENSMUST00000184908.1
POU6F1
POU domain, class 6, transcription factor 1 (Pou6f1), mRNA
chr10_+_93488766 0.097 ENSMUST00000129421.1
Hal
histidine ammonia lyase
chr9_+_110305185 0.079 ENSMUST00000068071.7
Elp6
elongator acetyltransferase complex subunit 6
chr6_+_17463826 0.077 ENSMUST00000140070.1
Met
met proto-oncogene
chr11_+_115420059 0.070 ENSMUST00000103035.3
Kctd2
potassium channel tetramerisation domain containing 2
chr7_-_6331235 0.069 ENSMUST00000127658.1
ENSMUST00000062765.7
Zfp583

zinc finger protein 583

chr2_+_85037212 0.067 ENSMUST00000077798.6
Ssrp1
structure specific recognition protein 1
chr8_-_72213636 0.060 ENSMUST00000109987.1
Gm11034
predicted gene 11034
chr11_-_115419917 0.056 ENSMUST00000106537.1
ENSMUST00000043931.2
ENSMUST00000073791.3
Atp5h


ATP synthase, H+ transporting, mitochondrial F0 complex, subunit d


chr15_-_100669512 0.039 ENSMUST00000182574.1
ENSMUST00000182775.1
Bin2

bridging integrator 2

chr11_-_45955465 0.036 ENSMUST00000011398.6
Thg1l
tRNA-histidine guanylyltransferase 1-like (S. cerevisiae)
chr14_+_55560480 0.035 ENSMUST00000121622.1
ENSMUST00000143431.1
ENSMUST00000150481.1
Dcaf11


DDB1 and CUL4 associated factor 11


chr13_+_6548154 0.034 ENSMUST00000021611.8
Pitrm1
pitrilysin metallepetidase 1
chr2_+_164879358 0.024 ENSMUST00000041643.3
Pcif1
PDX1 C-terminal inhibiting factor 1
chr4_-_155863362 0.022 ENSMUST00000030949.3
Tas1r3
taste receptor, type 1, member 3
chr17_-_89910449 0.020 ENSMUST00000086423.4
Gm10184
predicted pseudogene 10184
chr11_+_70214105 0.020 ENSMUST00000094055.3
ENSMUST00000136328.1
ENSMUST00000126296.1
ENSMUST00000153993.2
Slc16a11



solute carrier family 16 (monocarboxylic acid transporters), member 11



chr13_+_81783220 0.015 ENSMUST00000022009.8
Cetn3
centrin 3
chr4_+_40948401 0.010 ENSMUST00000030128.5
Chmp5
charged multivesicular body protein 5
chr4_+_133011506 0.005 ENSMUST00000105915.1
ENSMUST00000105916.1
Ahdc1

AT hook, DNA binding motif, containing 1

chr11_+_78245743 0.004 ENSMUST00000002133.8
Sdf2
stromal cell derived factor 2
chr11_-_45955183 0.003 ENSMUST00000109254.1
Thg1l
tRNA-histidine guanylyltransferase 1-like (S. cerevisiae)
chr7_+_24370255 0.002 ENSMUST00000171904.1
Kcnn4
potassium intermediate/small conductance calcium-activated channel, subfamily N, member 4

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
1.2 3.6 GO:0010751 negative regulation of nitric oxide mediated signal transduction(GO:0010751)
0.8 2.5 GO:0016332 establishment or maintenance of polarity of embryonic epithelium(GO:0016332)
0.8 2.5 GO:0071336 white fat cell proliferation(GO:0070343) regulation of white fat cell proliferation(GO:0070350) regulation of hair follicle cell proliferation(GO:0071336) positive regulation of hair follicle cell proliferation(GO:0071338)
0.7 2.7 GO:1904565 response to 1-oleoyl-sn-glycerol 3-phosphate(GO:1904565) cellular response to 1-oleoyl-sn-glycerol 3-phosphate(GO:1904566)
0.6 1.9 GO:2000331 regulation of terminal button organization(GO:2000331)
0.6 3.1 GO:1990034 calcium ion export from cell(GO:1990034)
0.6 8.5 GO:1902004 positive regulation of beta-amyloid formation(GO:1902004)
0.5 2.1 GO:0046967 cytosol to ER transport(GO:0046967)
0.5 5.0 GO:0046543 development of secondary female sexual characteristics(GO:0046543)
0.4 2.2 GO:0035864 response to potassium ion(GO:0035864) cellular response to potassium ion(GO:0035865)
0.4 1.3 GO:2000850 protein-chromophore linkage(GO:0018298) negative regulation of corticosteroid hormone secretion(GO:2000847) negative regulation of glucocorticoid secretion(GO:2000850)
0.4 2.1 GO:0045162 clustering of voltage-gated sodium channels(GO:0045162)
0.3 2.4 GO:0051798 positive regulation of hair follicle development(GO:0051798)
0.3 1.1 GO:0019355 nicotinamide nucleotide biosynthetic process from aspartate(GO:0019355) 'de novo' NAD biosynthetic process(GO:0034627) 'de novo' NAD biosynthetic process from aspartate(GO:0034628)
0.3 2.0 GO:0050882 voluntary musculoskeletal movement(GO:0050882)
0.3 2.8 GO:0010650 positive regulation of cell communication by electrical coupling(GO:0010650) positive regulation of membrane depolarization during cardiac muscle cell action potential(GO:1900827)
0.2 0.7 GO:1904978 regulation of endosome organization(GO:1904978) positive regulation of endosome organization(GO:1904980)
0.2 2.3 GO:0030322 stabilization of membrane potential(GO:0030322)
0.2 2.1 GO:0071420 cellular response to histamine(GO:0071420)
0.2 1.5 GO:0098909 establishment or maintenance of neuroblast polarity(GO:0045196) establishment of neuroblast polarity(GO:0045200) regulation of cardiac muscle cell action potential involved in regulation of contraction(GO:0098909)
0.2 1.0 GO:0021993 initiation of neural tube closure(GO:0021993)
0.2 0.6 GO:0019676 ammonia assimilation cycle(GO:0019676)
0.2 0.8 GO:0006751 glutathione catabolic process(GO:0006751)
0.2 0.7 GO:0046898 response to cycloheximide(GO:0046898)
0.1 1.0 GO:1990416 positive regulation of neurotrophin TRK receptor signaling pathway(GO:0051388) cellular response to brain-derived neurotrophic factor stimulus(GO:1990416)
0.1 0.7 GO:0071985 multivesicular body sorting pathway(GO:0071985)
0.1 0.9 GO:0007296 vitellogenesis(GO:0007296)
0.1 2.7 GO:0042711 maternal behavior(GO:0042711)
0.1 1.6 GO:1901898 regulation of cell communication by electrical coupling involved in cardiac conduction(GO:1901844) negative regulation of relaxation of cardiac muscle(GO:1901898)
0.1 1.4 GO:1900121 negative regulation of receptor binding(GO:1900121)
0.1 1.5 GO:0045019 negative regulation of nitric oxide biosynthetic process(GO:0045019) negative regulation of nitric oxide metabolic process(GO:1904406)
0.1 2.0 GO:0001553 luteinization(GO:0001553)
0.1 1.9 GO:0021902 commitment of neuronal cell to specific neuron type in forebrain(GO:0021902)
0.1 0.7 GO:2000672 negative regulation of motor neuron apoptotic process(GO:2000672)
0.1 0.4 GO:0000957 mitochondrial RNA catabolic process(GO:0000957) regulation of mitochondrial RNA catabolic process(GO:0000960)
0.1 0.5 GO:1904721 regulation of mRNA cleavage(GO:0031437) negative regulation of mRNA cleavage(GO:0031438) negative regulation of immunoglobulin secretion(GO:0051025) regulation of mRNA endonucleolytic cleavage involved in unfolded protein response(GO:1904720) negative regulation of mRNA endonucleolytic cleavage involved in unfolded protein response(GO:1904721)
0.1 1.6 GO:0097119 postsynaptic density protein 95 clustering(GO:0097119)
0.1 0.3 GO:0010838 positive regulation of keratinocyte proliferation(GO:0010838)
0.1 0.6 GO:0071630 nucleus-associated proteasomal ubiquitin-dependent protein catabolic process(GO:0071630)
0.1 0.6 GO:0007021 tubulin complex assembly(GO:0007021)
0.1 0.7 GO:0032811 negative regulation of gamma-aminobutyric acid secretion(GO:0014053) negative regulation of epinephrine secretion(GO:0032811)
0.1 1.1 GO:0031639 plasminogen activation(GO:0031639)
0.1 0.6 GO:0034975 protein folding in endoplasmic reticulum(GO:0034975)
0.1 0.5 GO:0006452 translational frameshifting(GO:0006452) positive regulation of translational termination(GO:0045905)
0.1 1.7 GO:0051764 actin crosslink formation(GO:0051764)
0.1 0.4 GO:1902775 mitochondrial large ribosomal subunit assembly(GO:1902775)
0.1 0.7 GO:0031118 rRNA pseudouridine synthesis(GO:0031118)
0.1 0.6 GO:0014029 neural crest formation(GO:0014029)
0.1 0.2 GO:1903028 regulation of opsonization(GO:1903027) positive regulation of opsonization(GO:1903028)
0.1 0.4 GO:0032790 ribosome disassembly(GO:0032790)
0.1 1.3 GO:0042104 positive regulation of activated T cell proliferation(GO:0042104)
0.1 0.2 GO:0001180 transcription initiation from RNA polymerase I promoter for nuclear large rRNA transcript(GO:0001180)
0.0 0.2 GO:1990481 mRNA pseudouridine synthesis(GO:1990481)
0.0 0.2 GO:0060709 glycogen cell differentiation involved in embryonic placenta development(GO:0060709)
0.0 0.2 GO:1901097 negative regulation of autophagosome maturation(GO:1901097)
0.0 0.9 GO:0007530 sex determination(GO:0007530)
0.0 0.2 GO:0009957 epidermal cell fate specification(GO:0009957)
0.0 0.2 GO:0070562 regulation of vitamin D receptor signaling pathway(GO:0070562)
0.0 1.8 GO:0007218 neuropeptide signaling pathway(GO:0007218)
0.0 0.3 GO:2000491 positive regulation of hepatic stellate cell activation(GO:2000491)
0.0 1.9 GO:0003407 neural retina development(GO:0003407)
0.0 0.2 GO:0051490 negative regulation of filopodium assembly(GO:0051490)
0.0 0.5 GO:0033539 fatty acid beta-oxidation using acyl-CoA dehydrogenase(GO:0033539)
0.0 0.1 GO:0072014 proximal tubule development(GO:0072014)
0.0 0.6 GO:0061003 positive regulation of dendritic spine morphogenesis(GO:0061003)
0.0 0.1 GO:0006547 histidine metabolic process(GO:0006547) imidazole-containing compound catabolic process(GO:0052805)
0.0 0.3 GO:1900113 negative regulation of histone H3-K9 trimethylation(GO:1900113)
0.0 0.8 GO:0007520 myoblast fusion(GO:0007520)
0.0 0.1 GO:0061086 negative regulation of histone H3-K27 methylation(GO:0061086) chromatin maintenance(GO:0070827)
0.0 0.3 GO:0021516 dorsal spinal cord development(GO:0021516)
0.0 1.3 GO:0051965 positive regulation of synapse assembly(GO:0051965)
0.0 1.3 GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)
0.0 3.4 GO:0002757 immune response-activating signal transduction(GO:0002757)
0.0 0.2 GO:0043508 negative regulation of JUN kinase activity(GO:0043508)
0.0 2.4 GO:0007050 cell cycle arrest(GO:0007050)
0.0 0.1 GO:0016339 calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0016339)
0.0 0.8 GO:0035383 acyl-CoA metabolic process(GO:0006637) thioester metabolic process(GO:0035383)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.9 2.7 GO:0005577 fibrinogen complex(GO:0005577)
0.5 1.5 GO:0031088 platelet dense granule membrane(GO:0031088)
0.3 2.1 GO:0042825 TAP complex(GO:0042825)
0.1 4.9 GO:0043194 axon initial segment(GO:0043194)
0.1 2.1 GO:1902711 GABA-A receptor complex(GO:1902711)
0.1 0.7 GO:0032585 multivesicular body membrane(GO:0032585)
0.1 0.7 GO:0038039 G-protein coupled receptor heterodimeric complex(GO:0038039)
0.1 0.4 GO:0097058 CRLF-CLCF1 complex(GO:0097058)
0.1 0.6 GO:0097512 cardiac myofibril(GO:0097512)
0.1 1.3 GO:0097539 ciliary transition fiber(GO:0097539)
0.1 1.0 GO:0031209 SCAR complex(GO:0031209)
0.1 1.2 GO:1904115 axon cytoplasm(GO:1904115)
0.1 0.3 GO:0090661 box H/ACA telomerase RNP complex(GO:0090661)
0.1 0.7 GO:0097136 Bcl-2 family protein complex(GO:0097136)
0.0 1.0 GO:0097228 sperm principal piece(GO:0097228)
0.0 0.6 GO:0072546 ER membrane protein complex(GO:0072546)
0.0 0.5 GO:0005642 annulate lamellae(GO:0005642)
0.0 1.6 GO:0005891 voltage-gated calcium channel complex(GO:0005891)
0.0 1.9 GO:0060170 ciliary membrane(GO:0060170)
0.0 3.1 GO:0031594 neuromuscular junction(GO:0031594)
0.0 4.7 GO:0043204 perikaryon(GO:0043204)
0.0 4.6 GO:0030139 endocytic vesicle(GO:0030139)
0.0 1.9 GO:0044295 axonal growth cone(GO:0044295)
0.0 0.7 GO:0030132 clathrin coat of coated pit(GO:0030132)
0.0 1.7 GO:0031941 filamentous actin(GO:0031941)
0.0 8.9 GO:0045211 postsynaptic membrane(GO:0045211)
0.0 1.6 GO:0014704 intercalated disc(GO:0014704)
0.0 0.2 GO:0000120 RNA polymerase I transcription factor complex(GO:0000120)
0.0 0.2 GO:0005726 perichromatin fibrils(GO:0005726)
0.0 0.6 GO:0012507 ER to Golgi transport vesicle membrane(GO:0012507)
0.0 0.2 GO:0031595 nuclear proteasome complex(GO:0031595)
0.0 1.8 GO:0000118 histone deacetylase complex(GO:0000118)
0.0 0.8 GO:0042645 nucleoid(GO:0009295) mitochondrial nucleoid(GO:0042645)
0.0 1.1 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.0 6.5 GO:0031012 extracellular matrix(GO:0031012)
0.0 0.9 GO:0010494 cytoplasmic stress granule(GO:0010494)
0.0 0.9 GO:0043195 terminal bouton(GO:0043195)
0.0 1.1 GO:0031225 anchored component of membrane(GO:0031225)
0.0 0.1 GO:0033588 Elongator holoenzyme complex(GO:0033588)
0.0 0.1 GO:0031618 nuclear pericentric heterochromatin(GO:0031618)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.9 2.7 GO:0070052 collagen V binding(GO:0070052)
0.6 2.5 GO:1902379 chemoattractant activity involved in axon guidance(GO:1902379)
0.6 2.5 GO:0005111 type 2 fibroblast growth factor receptor binding(GO:0005111)
0.6 1.8 GO:0004994 somatostatin receptor activity(GO:0004994)
0.5 2.1 GO:0015433 peptide antigen-transporting ATPase activity(GO:0015433) tapasin binding(GO:0046980)
0.5 1.5 GO:0005220 inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0005220)
0.4 2.1 GO:0086080 protein binding involved in heterotypic cell-cell adhesion(GO:0086080)
0.4 1.3 GO:0009881 photoreceptor activity(GO:0009881)
0.4 2.7 GO:0035727 lysophosphatidic acid binding(GO:0035727) lysophosphatidic acid receptor activity(GO:0070915)
0.4 1.5 GO:0004609 phosphatidylserine decarboxylase activity(GO:0004609)
0.3 3.1 GO:0005432 calcium:sodium antiporter activity(GO:0005432)
0.3 1.1 GO:0004515 nicotinamide-nucleotide adenylyltransferase activity(GO:0000309) nicotinate-nucleotide adenylyltransferase activity(GO:0004515)
0.3 0.8 GO:0003986 acetyl-CoA hydrolase activity(GO:0003986)
0.2 2.4 GO:0048185 activin binding(GO:0048185)
0.2 2.3 GO:0022841 potassium ion leak channel activity(GO:0022841)
0.2 0.6 GO:0016880 acid-ammonia (or amide) ligase activity(GO:0016880)
0.2 1.7 GO:0035374 chondroitin sulfate binding(GO:0035374)
0.2 0.5 GO:0017099 very-long-chain-acyl-CoA dehydrogenase activity(GO:0017099)
0.2 0.8 GO:0003839 gamma-glutamylcyclotransferase activity(GO:0003839)
0.2 1.3 GO:0031995 insulin-like growth factor II binding(GO:0031995)
0.1 2.4 GO:0030235 nitric-oxide synthase regulator activity(GO:0030235)
0.1 0.7 GO:0043812 phosphatidylinositol-4-phosphate phosphatase activity(GO:0043812)
0.1 0.8 GO:1904315 GABA-gated chloride ion channel activity(GO:0022851) transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1904315)
0.1 1.4 GO:1990459 transferrin receptor binding(GO:1990459)
0.1 0.7 GO:0004965 G-protein coupled GABA receptor activity(GO:0004965)
0.1 1.9 GO:0042043 neurexin family protein binding(GO:0042043)
0.1 1.3 GO:0004890 GABA-A receptor activity(GO:0004890)
0.1 0.3 GO:0050501 hyaluronan synthase activity(GO:0050501)
0.1 0.5 GO:0060698 endoribonuclease inhibitor activity(GO:0060698)
0.1 10.1 GO:0004860 protein kinase inhibitor activity(GO:0004860)
0.1 0.7 GO:0051434 BH3 domain binding(GO:0051434)
0.1 2.5 GO:0005070 SH3/SH2 adaptor activity(GO:0005070)
0.1 1.3 GO:0051864 histone demethylase activity (H3-K36 specific)(GO:0051864)
0.1 5.0 GO:0005080 protein kinase C binding(GO:0005080)
0.1 0.6 GO:0005212 structural constituent of eye lens(GO:0005212)
0.1 0.2 GO:0005119 smoothened binding(GO:0005119) hedgehog receptor activity(GO:0008158)
0.1 0.4 GO:0005127 ciliary neurotrophic factor receptor binding(GO:0005127)
0.0 4.1 GO:0005200 structural constituent of cytoskeleton(GO:0005200)
0.0 1.1 GO:0042605 peptide antigen binding(GO:0042605)
0.0 1.6 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
0.0 1.0 GO:0003950 NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.0 0.9 GO:0043008 ATP-dependent protein binding(GO:0043008)
0.0 0.1 GO:0035939 microsatellite binding(GO:0035939)
0.0 0.6 GO:0009982 pseudouridine synthase activity(GO:0009982)
0.0 1.4 GO:0043027 cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027)
0.0 0.4 GO:0043024 ribosomal small subunit binding(GO:0043024)
0.0 2.1 GO:0048487 beta-tubulin binding(GO:0048487)
0.0 0.3 GO:0034513 box H/ACA snoRNA binding(GO:0034513)
0.0 0.3 GO:0000774 adenyl-nucleotide exchange factor activity(GO:0000774)
0.0 0.5 GO:0017070 U6 snRNA binding(GO:0017070)
0.0 0.7 GO:0031489 myosin V binding(GO:0031489)
0.0 0.2 GO:0034056 estrogen response element binding(GO:0034056)
0.0 0.9 GO:0001106 RNA polymerase II transcription corepressor activity(GO:0001106)
0.0 0.3 GO:0035925 mRNA 3'-UTR AU-rich region binding(GO:0035925)
0.0 1.9 GO:0005262 calcium channel activity(GO:0005262)
0.0 0.1 GO:0016841 ammonia-lyase activity(GO:0016841)
0.0 0.6 GO:0005484 SNAP receptor activity(GO:0005484)
0.0 0.0 GO:0008192 RNA guanylyltransferase activity(GO:0008192)
0.0 0.1 GO:0000990 transcription factor activity, core RNA polymerase binding(GO:0000990)
0.0 0.0 GO:0008527 taste receptor activity(GO:0008527)
0.0 0.2 GO:0001163 RNA polymerase I regulatory region sequence-specific DNA binding(GO:0001163) RNA polymerase I CORE element sequence-specific DNA binding(GO:0001164)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 2.5 PID_WNT_SIGNALING_PATHWAY Wnt signaling network
0.1 3.8 PID_BMP_PATHWAY BMP receptor signaling
0.1 10.6 NABA_ECM_GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.1 1.3 PID_CIRCADIAN_PATHWAY Circadian rhythm pathway
0.1 1.5 ST_WNT_CA2_CYCLIC_GMP_PATHWAY Wnt/Ca2+/cyclic GMP signaling.
0.1 2.9 ST_ERK1_ERK2_MAPK_PATHWAY ERK1/ERK2 MAPK Pathway
0.0 0.7 SA_PROGRAMMED_CELL_DEATH Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.
0.0 1.2 SIG_REGULATION_OF_THE_ACTIN_CYTOSKELETON_BY_RHO_GTPASES Genes related to regulation of the actin cytoskeleton
0.0 1.2 PID_HNF3A_PATHWAY FOXA1 transcription factor network
0.0 1.9 PID_LYSOPHOSPHOLIPID_PATHWAY LPA receptor mediated events
0.0 1.3 PID_PLK1_PATHWAY PLK1 signaling events
0.0 0.7 PID_EPHB_FWD_PATHWAY EPHB forward signaling
0.0 3.5 NABA_SECRETED_FACTORS Genes encoding secreted soluble factors
0.0 1.0 PID_BCR_5PATHWAY BCR signaling pathway
0.0 1.1 PID_AR_PATHWAY Coregulation of Androgen receptor activity
0.0 1.2 PID_P53_DOWNSTREAM_PATHWAY Direct p53 effectors

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 2.3 REACTOME_TANDEM_PORE_DOMAIN_POTASSIUM_CHANNELS Genes involved in Tandem pore domain potassium channels
0.2 3.1 REACTOME_PLATELET_CALCIUM_HOMEOSTASIS Genes involved in Platelet calcium homeostasis
0.2 2.5 REACTOME_FGFR1_LIGAND_BINDING_AND_ACTIVATION Genes involved in FGFR1 ligand binding and activation
0.2 2.5 REACTOME_SIGNAL_REGULATORY_PROTEIN_SIRP_FAMILY_INTERACTIONS Genes involved in Signal regulatory protein (SIRP) family interactions
0.1 4.9 REACTOME_INTERACTION_BETWEEN_L1_AND_ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.1 2.1 REACTOME_GABA_A_RECEPTOR_ACTIVATION Genes involved in GABA A receptor activation
0.1 2.1 REACTOME_ANTIGEN_PRESENTATION_FOLDING_ASSEMBLY_AND_PEPTIDE_LOADING_OF_CLASS_I_MHC Genes involved in Antigen Presentation: Folding, assembly and peptide loading of class I MHC
0.1 1.7 REACTOME_CRMPS_IN_SEMA3A_SIGNALING Genes involved in CRMPs in Sema3A signaling
0.1 1.3 REACTOME_REGULATION_OF_INSULIN_LIKE_GROWTH_FACTOR_IGF_ACTIVITY_BY_INSULIN_LIKE_GROWTH_FACTOR_BINDING_PROTEINS_IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.1 1.4 REACTOME_ACTIVATION_OF_BH3_ONLY_PROTEINS Genes involved in Activation of BH3-only proteins
0.1 0.7 REACTOME_INFLAMMASOMES Genes involved in Inflammasomes
0.1 0.7 REACTOME_CLASS_C_3_METABOTROPIC_GLUTAMATE_PHEROMONE_RECEPTORS Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors)
0.0 1.1 REACTOME_CHOLESTEROL_BIOSYNTHESIS Genes involved in Cholesterol biosynthesis
0.0 1.6 REACTOME_DARPP_32_EVENTS Genes involved in DARPP-32 events
0.0 1.2 REACTOME_MYOGENESIS Genes involved in Myogenesis
0.0 1.0 REACTOME_ERK_MAPK_TARGETS Genes involved in ERK/MAPK targets
0.0 4.5 REACTOME_CLASS_A1_RHODOPSIN_LIKE_RECEPTORS Genes involved in Class A/1 (Rhodopsin-like receptors)
0.0 2.7 REACTOME_INTEGRIN_CELL_SURFACE_INTERACTIONS Genes involved in Integrin cell surface interactions
0.0 2.5 REACTOME_GPCR_LIGAND_BINDING Genes involved in GPCR ligand binding
0.0 1.3 REACTOME_BMAL1_CLOCK_NPAS2_ACTIVATES_CIRCADIAN_EXPRESSION Genes involved in BMAL1:CLOCK/NPAS2 Activates Circadian Expression
0.0 1.4 REACTOME_NETRIN1_SIGNALING Genes involved in Netrin-1 signaling
0.0 0.3 REACTOME_DESTABILIZATION_OF_MRNA_BY_KSRP Genes involved in Destabilization of mRNA by KSRP
0.0 0.6 REACTOME_AMINO_ACID_SYNTHESIS_AND_INTERCONVERSION_TRANSAMINATION Genes involved in Amino acid synthesis and interconversion (transamination)
0.0 0.3 REACTOME_HYALURONAN_METABOLISM Genes involved in Hyaluronan metabolism
0.0 0.7 REACTOME_SYNTHESIS_OF_PIPS_AT_THE_PLASMA_MEMBRANE Genes involved in Synthesis of PIPs at the plasma membrane
0.0 0.5 REACTOME_PTM_GAMMA_CARBOXYLATION_HYPUSINE_FORMATION_AND_ARYLSULFATASE_ACTIVATION Genes involved in PTM: gamma carboxylation, hypusine formation and arylsulfatase activation
0.0 0.4 REACTOME_SIGNALING_BY_FGFR1_FUSION_MUTANTS Genes involved in Signaling by FGFR1 fusion mutants
0.0 1.1 REACTOME_METABOLISM_OF_VITAMINS_AND_COFACTORS Genes involved in Metabolism of vitamins and cofactors