Motif ID: Gli3_Zic1

Z-value: 0.889

Transcription factors associated with Gli3_Zic1:

Gene SymbolEntrez IDGene Name
Gli3 ENSMUSG00000021318.9 Gli3
Zic1 ENSMUSG00000032368.8 Zic1

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Gli3mm10_v2_chr13_+_15463202_15463240-0.617.3e-05Click!
Zic1mm10_v2_chr9_-_91365778_91365815-0.391.7e-02Click!





Network of associatons between targets according to the STRING database.



First level regulatory network of Gli3_Zic1

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr16_+_91269759 5.704 ENSMUST00000056882.5
Olig1
oligodendrocyte transcription factor 1
chr8_+_70501116 4.659 ENSMUST00000127983.1
Crlf1
cytokine receptor-like factor 1
chr11_-_42182163 4.258 ENSMUST00000153147.1
Gabra1
gamma-aminobutyric acid (GABA) A receptor, subunit alpha 1
chr1_+_195017399 3.947 ENSMUST00000181273.1
A330023F24Rik
RIKEN cDNA A330023F24 gene
chr7_+_5056706 3.914 ENSMUST00000144802.1
Ccdc106
coiled-coil domain containing 106
chr2_-_155945282 3.867 ENSMUST00000040162.2
Gdf5
growth differentiation factor 5
chr6_+_17463749 3.804 ENSMUST00000115443.1
Met
met proto-oncogene
chr7_+_5056856 3.757 ENSMUST00000131368.1
ENSMUST00000123956.1
Ccdc106

coiled-coil domain containing 106

chr17_-_68004075 3.748 ENSMUST00000024840.5
Arhgap28
Rho GTPase activating protein 28
chr7_+_5057161 3.704 ENSMUST00000045543.5
Ccdc106
coiled-coil domain containing 106
chr8_-_105966038 2.936 ENSMUST00000116429.2
ENSMUST00000034370.9
Slc12a4

solute carrier family 12, member 4

chr13_+_118714678 2.843 ENSMUST00000022246.8
Fgf10
fibroblast growth factor 10
chr8_+_76902277 2.692 ENSMUST00000109912.1
ENSMUST00000128862.1
ENSMUST00000109911.1
Nr3c2


nuclear receptor subfamily 3, group C, member 2


chr9_-_56418023 2.627 ENSMUST00000061552.8
C230081A13Rik
RIKEN cDNA C230081A13 gene
chr7_-_142657466 2.622 ENSMUST00000097936.2
ENSMUST00000000033.5
Igf2

insulin-like growth factor 2

chr15_-_95528228 2.522 ENSMUST00000075275.2
Nell2
NEL-like 2
chr6_+_17463826 2.436 ENSMUST00000140070.1
Met
met proto-oncogene
chr6_+_110645572 2.372 ENSMUST00000071076.6
ENSMUST00000172951.1
Grm7

glutamate receptor, metabotropic 7

chr3_+_68494208 2.323 ENSMUST00000182719.1
Schip1
schwannomin interacting protein 1
chr9_-_54661870 2.313 ENSMUST00000034822.5
Acsbg1
acyl-CoA synthetase bubblegum family member 1
chr14_-_55560340 2.250 ENSMUST00000066106.3
A730061H03Rik
RIKEN cDNA A730061H03 gene
chr2_-_36104060 2.238 ENSMUST00000112961.3
ENSMUST00000112966.3
Lhx6

LIM homeobox protein 6

chr11_-_70229677 2.173 ENSMUST00000153449.1
ENSMUST00000000326.5
Bcl6b

B cell CLL/lymphoma 6, member B

chr15_-_95528702 2.119 ENSMUST00000166170.1
Nell2
NEL-like 2
chr9_+_50752758 2.113 ENSMUST00000034562.7
Cryab
crystallin, alpha B
chr13_-_117025505 2.103 ENSMUST00000022239.6
Parp8
poly (ADP-ribose) polymerase family, member 8
chrX_-_7574120 2.017 ENSMUST00000045924.7
ENSMUST00000115742.2
ENSMUST00000150787.1
Ppp1r3f


protein phosphatase 1, regulatory (inhibitor) subunit 3F


chr6_+_17463927 1.971 ENSMUST00000115442.1
Met
met proto-oncogene
chr1_-_56972437 1.937 ENSMUST00000042857.7
Satb2
special AT-rich sequence binding protein 2
chr3_+_31149934 1.886 ENSMUST00000046174.6
Cldn11
claudin 11
chr10_-_127341583 1.881 ENSMUST00000026474.3
Gli1
GLI-Kruppel family member GLI1
chr5_+_30588078 1.879 ENSMUST00000066295.2
Kcnk3
potassium channel, subfamily K, member 3
chr11_+_93098404 1.875 ENSMUST00000107859.1
ENSMUST00000042943.6
ENSMUST00000107861.1
ENSMUST00000107858.2
Car10



carbonic anhydrase 10



chr7_-_84605819 1.833 ENSMUST00000032865.9
Fah
fumarylacetoacetate hydrolase
chr7_-_19698383 1.823 ENSMUST00000173739.1
Apoe
apolipoprotein E
chr11_-_42000284 1.794 ENSMUST00000109292.2
ENSMUST00000109290.1
Gabrg2

gamma-aminobutyric acid (GABA) A receptor, subunit gamma 2

chr17_-_24650270 1.762 ENSMUST00000002572.4
Slc9a3r2
solute carrier family 9 (sodium/hydrogen exchanger), member 3 regulator 2
chr4_+_124657646 1.747 ENSMUST00000053491.7
Pou3f1
POU domain, class 3, transcription factor 1
chr1_-_180483410 1.745 ENSMUST00000136521.1
ENSMUST00000179826.1
6330403A02Rik

RIKEN cDNA 6330403A02 gene

chr11_-_42000532 1.729 ENSMUST00000070735.3
Gabrg2
gamma-aminobutyric acid (GABA) A receptor, subunit gamma 2
chr11_+_101246405 1.721 ENSMUST00000122006.1
ENSMUST00000151830.1
Ramp2

receptor (calcitonin) activity modifying protein 2

chr8_-_105637403 1.703 ENSMUST00000182046.1
Gm5914
predicted gene 5914
chr4_-_136956784 1.701 ENSMUST00000030420.8
Epha8
Eph receptor A8
chr2_+_70562007 1.699 ENSMUST00000094934.4
Gad1
glutamate decarboxylase 1
chr12_+_109545390 1.639 ENSMUST00000146701.1
Meg3
maternally expressed 3
chr6_-_113531575 1.627 ENSMUST00000032425.5
Emc3
ER membrane protein complex subunit 3
chr17_-_24209377 1.623 ENSMUST00000024931.4
Ntn3
netrin 3
chr13_+_81783220 1.584 ENSMUST00000022009.8
Cetn3
centrin 3
chr6_+_86195214 1.575 ENSMUST00000032066.9
Tgfa
transforming growth factor alpha
chr6_+_17491216 1.574 ENSMUST00000080469.5
Met
met proto-oncogene
chr12_+_73997749 1.459 ENSMUST00000110451.2
Syt16
synaptotagmin XVI
chr8_-_105637350 1.437 ENSMUST00000182863.1
Gm5914
predicted gene 5914
chr11_+_101246960 1.425 ENSMUST00000107282.3
Ramp2
receptor (calcitonin) activity modifying protein 2
chr6_-_35308110 1.287 ENSMUST00000031868.4
Slc13a4
solute carrier family 13 (sodium/sulfate symporters), member 4
chr18_-_38601268 1.282 ENSMUST00000025295.6
Spry4
sprouty homolog 4 (Drosophila)
chr9_-_123678782 1.219 ENSMUST00000170591.1
ENSMUST00000171647.1
Slc6a20a

solute carrier family 6 (neurotransmitter transporter), member 20A

chr4_+_48045144 1.205 ENSMUST00000030025.3
Nr4a3
nuclear receptor subfamily 4, group A, member 3
chrX_-_167382747 1.191 ENSMUST00000026839.4
Prps2
phosphoribosyl pyrophosphate synthetase 2
chr19_-_32388462 1.176 ENSMUST00000099514.3
Sgms1
sphingomyelin synthase 1
chr19_-_4698315 1.175 ENSMUST00000096325.3
Gm960
predicted gene 960
chr5_+_71699918 1.164 ENSMUST00000031122.7
Gabrb1
gamma-aminobutyric acid (GABA) A receptor, subunit beta 1
chr8_-_69887687 1.159 ENSMUST00000057831.7
Cilp2
cartilage intermediate layer protein 2
chr8_+_54954728 1.155 ENSMUST00000033915.7
Gpm6a
glycoprotein m6a
chr9_+_86695542 1.123 ENSMUST00000150367.2
A330041J22Rik
RIKEN cDNA A330041J22 gene
chr7_+_35119285 1.094 ENSMUST00000042985.9
Cebpa
CCAAT/enhancer binding protein (C/EBP), alpha
chr14_+_55560480 1.083 ENSMUST00000121622.1
ENSMUST00000143431.1
ENSMUST00000150481.1
Dcaf11


DDB1 and CUL4 associated factor 11


chr5_-_147725988 1.070 ENSMUST00000110529.1
ENSMUST00000031652.3
ENSMUST00000031653.5
Flt1


FMS-like tyrosine kinase 1


chr13_-_54611274 1.066 ENSMUST00000049575.7
Cltb
clathrin, light polypeptide (Lcb)
chr14_-_30353468 1.062 ENSMUST00000112249.1
Cacna1d
calcium channel, voltage-dependent, L type, alpha 1D subunit
chr8_+_68880491 1.050 ENSMUST00000015712.8
Lpl
lipoprotein lipase
chr11_+_87760533 1.032 ENSMUST00000039627.5
ENSMUST00000100644.3
Bzrap1

benzodiazepine receptor associated protein 1

chr11_+_75655873 1.023 ENSMUST00000108431.2
Myo1c
myosin IC
chr16_-_28445227 1.022 ENSMUST00000100024.1
Fgf12
fibroblast growth factor 12
chr7_+_57591147 1.019 ENSMUST00000039697.7
Gabrb3
gamma-aminobutyric acid (GABA) A receptor, subunit beta 3
chr2_+_32646586 1.014 ENSMUST00000009705.7
ENSMUST00000167841.1
Eng

endoglin

chr9_-_123678873 1.013 ENSMUST00000040960.6
Slc6a20a
solute carrier family 6 (neurotransmitter transporter), member 20A
chr4_+_144893077 0.988 ENSMUST00000154208.1
Dhrs3
dehydrogenase/reductase (SDR family) member 3
chr9_+_62858085 0.980 ENSMUST00000034777.6
ENSMUST00000163820.1
Calml4

calmodulin-like 4

chr6_-_125494754 0.943 ENSMUST00000032492.8
Cd9
CD9 antigen
chr6_+_125494419 0.914 ENSMUST00000181266.1
Gm26728
predicted gene, 26728
chr6_-_118780324 0.909 ENSMUST00000112793.3
ENSMUST00000075591.6
ENSMUST00000078320.7
ENSMUST00000112790.2
Cacna1c



calcium channel, voltage-dependent, L type, alpha 1C subunit



chr5_+_138995038 0.896 ENSMUST00000100518.2
6330403L08Rik
RIKEN cDNA 6330403L08 gene
chr13_-_54611332 0.893 ENSMUST00000091609.4
Cltb
clathrin, light polypeptide (Lcb)
chr7_-_100656953 0.893 ENSMUST00000107046.1
ENSMUST00000107045.1
ENSMUST00000139708.1
Plekhb1


pleckstrin homology domain containing, family B (evectins) member 1


chr2_-_29253001 0.888 ENSMUST00000071201.4
Ntng2
netrin G2
chrX_+_73064787 0.888 ENSMUST00000060418.6
Pnma3
paraneoplastic antigen MA3
chr1_-_22805994 0.887 ENSMUST00000097808.4
Rims1
regulating synaptic membrane exocytosis 1
chr10_+_80249441 0.876 ENSMUST00000020361.6
Ndufs7
NADH dehydrogenase (ubiquinone) Fe-S protein 7
chr16_-_46496955 0.871 ENSMUST00000023335.6
ENSMUST00000023334.8
Pvrl3

poliovirus receptor-related 3

chr5_-_138994935 0.865 ENSMUST00000046901.7
ENSMUST00000076095.7
Pdgfa

platelet derived growth factor, alpha

chrX_-_150812715 0.864 ENSMUST00000112697.3
Maged2
melanoma antigen, family D, 2
chrX_-_59568068 0.854 ENSMUST00000119833.1
ENSMUST00000131319.1
Fgf13

fibroblast growth factor 13

chr9_-_54661666 0.853 ENSMUST00000128624.1
Acsbg1
acyl-CoA synthetase bubblegum family member 1
chr1_-_153900198 0.850 ENSMUST00000123490.1
5830403L16Rik
RIKEN cDNA 5830403L16 gene
chr9_+_110305185 0.830 ENSMUST00000068071.7
Elp6
elongator acetyltransferase complex subunit 6
chr11_+_51289920 0.824 ENSMUST00000102765.2
Col23a1
collagen, type XXIII, alpha 1
chr6_-_28830345 0.820 ENSMUST00000171353.1
Lrrc4
leucine rich repeat containing 4
chr1_-_168431896 0.818 ENSMUST00000176540.1
Pbx1
pre B cell leukemia homeobox 1
chr19_-_5085483 0.814 ENSMUST00000140389.1
ENSMUST00000151413.1
ENSMUST00000077066.7
Tmem151a


transmembrane protein 151A


chr16_+_23107413 0.813 ENSMUST00000023599.6
ENSMUST00000168891.1
Eif4a2

eukaryotic translation initiation factor 4A2

chr8_-_85840877 0.812 ENSMUST00000034140.7
Itfg1
integrin alpha FG-GAP repeat containing 1
chr7_+_99535439 0.797 ENSMUST00000098266.2
ENSMUST00000179755.1
Arrb1

arrestin, beta 1

chr10_+_80249106 0.794 ENSMUST00000105364.1
Ndufs7
NADH dehydrogenase (ubiquinone) Fe-S protein 7
chr7_-_111779963 0.789 ENSMUST00000049430.8
ENSMUST00000106663.1
Galnt18

UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 18

chr11_-_69920892 0.775 ENSMUST00000152589.1
ENSMUST00000108612.1
ENSMUST00000108611.1
Eif5a


eukaryotic translation initiation factor 5A


chr4_+_15265798 0.764 ENSMUST00000062684.8
Tmem64
transmembrane protein 64
chr11_+_100415722 0.764 ENSMUST00000107400.2
Fkbp10
FK506 binding protein 10
chr17_-_15041457 0.754 ENSMUST00000097398.4
ENSMUST00000040746.6
ENSMUST00000097400.4
Tcte3

Gm3448
t-complex-associated testis expressed 3

predicted gene 3448
chr9_+_100643605 0.752 ENSMUST00000041418.6
Stag1
stromal antigen 1
chr16_-_46496772 0.751 ENSMUST00000149901.1
ENSMUST00000096052.2
Pvrl3

poliovirus receptor-related 3

chr10_+_127165118 0.742 ENSMUST00000006914.9
B4galnt1
beta-1,4-N-acetyl-galactosaminyl transferase 1
chr7_+_130865756 0.739 ENSMUST00000120441.1
Plekha1
pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 1
chr8_+_46492789 0.729 ENSMUST00000110371.1
Acsl1
acyl-CoA synthetase long-chain family member 1
chr7_+_25267669 0.709 ENSMUST00000169266.1
Cic
capicua homolog (Drosophila)
chr19_+_42045792 0.702 ENSMUST00000172244.1
ENSMUST00000081714.4
Hoga1

4-hydroxy-2-oxoglutarate aldolase 1

chr11_+_69765970 0.700 ENSMUST00000108642.1
ENSMUST00000156932.1
Zbtb4

zinc finger and BTB domain containing 4

chr11_+_70647258 0.694 ENSMUST00000037534.7
Rnf167
ring finger protein 167
chr5_-_37824580 0.690 ENSMUST00000063116.9
Msx1
msh homeobox 1
chr7_+_73391160 0.684 ENSMUST00000128471.1
Rgma
RGM domain family, member A
chr4_+_123183456 0.681 ENSMUST00000126995.1
Hpcal4
hippocalcin-like 4
chr16_+_17561885 0.677 ENSMUST00000171002.1
ENSMUST00000023441.4
P2rx6

purinergic receptor P2X, ligand-gated ion channel, 6

chr4_+_45848816 0.673 ENSMUST00000107782.1
ENSMUST00000030011.5
1300002K09Rik

RIKEN cDNA 1300002K09 gene

chr10_+_40349265 0.670 ENSMUST00000044672.4
ENSMUST00000095743.2
Cdk19

cyclin-dependent kinase 19

chr16_+_20733104 0.668 ENSMUST00000115423.1
ENSMUST00000007171.6
Chrd

chordin

chr2_+_35282380 0.661 ENSMUST00000028239.6
Gsn
gelsolin
chr6_+_29694204 0.660 ENSMUST00000046750.7
ENSMUST00000115250.3
Tspan33

tetraspanin 33

chr7_-_19770509 0.659 ENSMUST00000003061.7
Bcam
basal cell adhesion molecule
chrX_-_150812932 0.658 ENSMUST00000131241.1
ENSMUST00000147152.1
ENSMUST00000143843.1
Maged2


melanoma antigen, family D, 2


chr15_+_78899755 0.656 ENSMUST00000001226.3
ENSMUST00000061239.7
ENSMUST00000109698.2
Sh3bp1


SH3-domain binding protein 1


chr11_+_78245743 0.656 ENSMUST00000002133.8
Sdf2
stromal cell derived factor 2
chr1_-_75506331 0.650 ENSMUST00000113567.2
ENSMUST00000113565.2
Obsl1

obscurin-like 1

chr17_+_37050631 0.647 ENSMUST00000172792.1
ENSMUST00000174347.1
Gabbr1

gamma-aminobutyric acid (GABA) B receptor, 1

chr4_-_4138432 0.646 ENSMUST00000070375.7
Penk
preproenkephalin
chr16_-_85550417 0.646 ENSMUST00000175700.1
ENSMUST00000114174.2
Cyyr1

cysteine and tyrosine-rich protein 1

chr12_+_103314944 0.643 ENSMUST00000179363.1
Fam181a
family with sequence similarity 181, member A
chr4_-_154899077 0.639 ENSMUST00000030935.3
ENSMUST00000132281.1
Fam213b

family with sequence similarity 213, member B

chr9_+_100643755 0.622 ENSMUST00000133388.1
Stag1
stromal antigen 1
chr9_-_58158498 0.619 ENSMUST00000168864.2
Islr
immunoglobulin superfamily containing leucine-rich repeat
chr6_-_85502858 0.617 ENSMUST00000161546.1
ENSMUST00000161078.1
Fbxo41

F-box protein 41

chr19_-_6084679 0.615 ENSMUST00000161548.1
Zfpl1
zinc finger like protein 1
chr2_-_144527341 0.611 ENSMUST00000163701.1
ENSMUST00000081982.5
Dzank1

double zinc ribbon and ankyrin repeat domains 1

chr7_+_130865835 0.610 ENSMUST00000075181.4
ENSMUST00000048180.5
Plekha1

pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 1

chr6_-_85502980 0.607 ENSMUST00000159062.1
Fbxo41
F-box protein 41
chr17_+_25727726 0.607 ENSMUST00000047273.1
Rpusd1
RNA pseudouridylate synthase domain containing 1
chr7_-_142372210 0.606 ENSMUST00000084412.5
Ifitm10
interferon induced transmembrane protein 10
chr5_-_34187670 0.604 ENSMUST00000042701.6
ENSMUST00000119171.1
Mxd4

Max dimerization protein 4

chr13_+_54949388 0.600 ENSMUST00000026994.7
ENSMUST00000109994.2
Unc5a

unc-5 homolog A (C. elegans)

chr7_-_142656018 0.594 ENSMUST00000178921.1
Igf2
insulin-like growth factor 2
chr15_-_78718113 0.591 ENSMUST00000088592.4
Elfn2
leucine rich repeat and fibronectin type III, extracellular 2
chr11_+_73018986 0.586 ENSMUST00000092937.6
Camkk1
calcium/calmodulin-dependent protein kinase kinase 1, alpha
chr8_-_105295934 0.586 ENSMUST00000057855.3
Exoc3l
exocyst complex component 3-like
chr9_+_100643448 0.584 ENSMUST00000146312.1
ENSMUST00000129269.1
Stag1

stromal antigen 1

chr1_-_165460430 0.582 ENSMUST00000027856.7
Dcaf6
DDB1 and CUL4 associated factor 6
chr4_+_42949814 0.581 ENSMUST00000037872.3
ENSMUST00000098112.2
Dnajb5

DnaJ (Hsp40) homolog, subfamily B, member 5

chr4_-_128962420 0.580 ENSMUST00000119354.1
ENSMUST00000106068.1
ENSMUST00000030581.3
Adc


arginine decarboxylase


chr13_-_49320219 0.577 ENSMUST00000110086.1
Fgd3
FYVE, RhoGEF and PH domain containing 3
chr14_+_4334763 0.569 ENSMUST00000165466.1
2610042L04Rik
RIKEN cDNA 2610042L04 gene
chr1_+_42697146 0.559 ENSMUST00000054883.2
Pou3f3
POU domain, class 3, transcription factor 3
chr10_+_39612934 0.557 ENSMUST00000019987.6
Traf3ip2
TRAF3 interacting protein 2
chr8_+_11728105 0.556 ENSMUST00000110909.2
ENSMUST00000033908.6
Arhgef7

Rho guanine nucleotide exchange factor (GEF7)

chrX_+_119927196 0.543 ENSMUST00000040961.2
ENSMUST00000113366.1
Pabpc5

poly(A) binding protein, cytoplasmic 5

chr5_-_118244861 0.543 ENSMUST00000117177.1
ENSMUST00000133372.1
ENSMUST00000154786.1
ENSMUST00000121369.1
Rnft2



ring finger protein, transmembrane 2



chr1_-_134235420 0.541 ENSMUST00000038191.6
ENSMUST00000086465.4
Adora1

adenosine A1 receptor

chr2_+_164879358 0.539 ENSMUST00000041643.3
Pcif1
PDX1 C-terminal inhibiting factor 1
chr3_+_95624971 0.532 ENSMUST00000058230.6
ENSMUST00000037983.4
Ensa

endosulfine alpha

chr11_-_60352869 0.531 ENSMUST00000095254.5
ENSMUST00000102683.4
ENSMUST00000093048.6
ENSMUST00000093046.6
ENSMUST00000064019.8
ENSMUST00000102682.4
Tom1l2





target of myb1-like 2 (chicken)





chrX_+_155262443 0.525 ENSMUST00000026324.9
Acot9
acyl-CoA thioesterase 9
chr13_-_56895737 0.525 ENSMUST00000022023.6
ENSMUST00000109871.1
Trpc7

transient receptor potential cation channel, subfamily C, member 7

chr16_+_43503607 0.521 ENSMUST00000126100.1
ENSMUST00000123047.1
ENSMUST00000156981.1
Zbtb20


zinc finger and BTB domain containing 20


chr1_+_167598384 0.519 ENSMUST00000015987.3
Rxrg
retinoid X receptor gamma
chr16_-_44016387 0.517 ENSMUST00000036174.3
Gramd1c
GRAM domain containing 1C
chr6_-_101377897 0.508 ENSMUST00000075994.6
Pdzrn3
PDZ domain containing RING finger 3
chr2_-_77170592 0.505 ENSMUST00000164114.2
ENSMUST00000049544.7
Ccdc141

coiled-coil domain containing 141

chr3_-_101110278 0.504 ENSMUST00000102694.3
Ptgfrn
prostaglandin F2 receptor negative regulator
chr12_-_32953772 0.504 ENSMUST00000180391.1
ENSMUST00000181670.1
4933406C10Rik

RIKEN cDNA 4933406C10 gene

chr2_+_158667119 0.503 ENSMUST00000045503.4
Ppp1r16b
protein phosphatase 1, regulatory (inhibitor) subunit 16B
chr14_+_55560904 0.498 ENSMUST00000072530.4
ENSMUST00000128490.1
Dcaf11

DDB1 and CUL4 associated factor 11

chr7_+_128246812 0.493 ENSMUST00000164710.1
ENSMUST00000070656.5
Tgfb1i1

transforming growth factor beta 1 induced transcript 1

chr2_+_78869009 0.490 ENSMUST00000028398.7
Ube2e3
ubiquitin-conjugating enzyme E2E 3
chr1_-_134234492 0.487 ENSMUST00000169927.1
Adora1
adenosine A1 receptor
chr17_+_37045980 0.485 ENSMUST00000174456.1
Gabbr1
gamma-aminobutyric acid (GABA) B receptor, 1
chr15_-_98953541 0.483 ENSMUST00000097014.5
Tuba1a
tubulin, alpha 1A
chr2_-_168230353 0.482 ENSMUST00000154111.1
Dpm1
dolichol-phosphate (beta-D) mannosyltransferase 1
chr13_+_54575008 0.480 ENSMUST00000026988.4
Arl10
ADP-ribosylation factor-like 10
chr18_+_86394952 0.475 ENSMUST00000058829.2
Neto1
neuropilin (NRP) and tolloid (TLL)-like 1
chr6_+_43265582 0.474 ENSMUST00000031750.7
Arhgef5
Rho guanine nucleotide exchange factor (GEF) 5
chrX_-_59567348 0.474 ENSMUST00000124402.1
Fgf13
fibroblast growth factor 13
chr7_+_128246953 0.466 ENSMUST00000167965.1
Tgfb1i1
transforming growth factor beta 1 induced transcript 1
chrX_+_101299207 0.462 ENSMUST00000065858.2
Nlgn3
neuroligin 3
chr19_+_8735808 0.455 ENSMUST00000049424.9
Wdr74
WD repeat domain 74
chr3_+_116007457 0.451 ENSMUST00000029575.5
ENSMUST00000106501.1
Extl2

exostoses (multiple)-like 2

chr7_-_44306903 0.451 ENSMUST00000004587.9
Clec11a
C-type lectin domain family 11, member a
chr6_+_125009232 0.446 ENSMUST00000112428.1
Zfp384
zinc finger protein 384
chr1_-_168431695 0.443 ENSMUST00000176790.1
Pbx1
pre B cell leukemia homeobox 1
chr13_-_9764943 0.443 ENSMUST00000110634.1
Zmynd11
zinc finger, MYND domain containing 11
chr1_+_125561010 0.434 ENSMUST00000027580.4
Slc35f5
solute carrier family 35, member F5
chr14_+_3572023 0.430 ENSMUST00000178728.1
Gm3005
predicted gene 3005
chr13_+_54575020 0.430 ENSMUST00000156024.1
Arl10
ADP-ribosylation factor-like 10
chr13_-_63565520 0.428 ENSMUST00000021921.5
Ptch1
patched homolog 1
chr3_-_116253467 0.418 ENSMUST00000090473.5
Gpr88
G-protein coupled receptor 88

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
1.4 12.6 GO:0060665 regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling(GO:0060665)
1.1 10.0 GO:0071420 cellular response to histamine(GO:0071420)
0.9 3.7 GO:1904425 negative regulation of GTP binding(GO:1904425)
0.8 4.7 GO:2000672 negative regulation of motor neuron apoptotic process(GO:2000672)
0.6 3.2 GO:0060591 chondroblast differentiation(GO:0060591)
0.6 1.8 GO:1903002 regulation of lipid transport across blood brain barrier(GO:1903000) positive regulation of lipid transport across blood brain barrier(GO:1903002)
0.5 1.0 GO:0034372 very-low-density lipoprotein particle remodeling(GO:0034372)
0.5 3.1 GO:0097646 calcitonin family receptor signaling pathway(GO:0097646) amylin receptor signaling pathway(GO:0097647)
0.5 2.4 GO:0001661 conditioned taste aversion(GO:0001661)
0.5 1.9 GO:0060032 notochord regression(GO:0060032)
0.5 1.8 GO:0006558 L-phenylalanine metabolic process(GO:0006558) erythrose 4-phosphate/phosphoenolpyruvate family amino acid metabolic process(GO:1902221)
0.4 5.2 GO:2000465 regulation of glycogen (starch) synthase activity(GO:2000465)
0.4 4.6 GO:0046543 development of secondary female sexual characteristics(GO:0046543)
0.4 1.2 GO:0038095 positive regulation of mast cell cytokine production(GO:0032765) Fc-epsilon receptor signaling pathway(GO:0038095)
0.4 0.4 GO:0007521 muscle cell fate determination(GO:0007521)
0.4 2.2 GO:1904936 cerebral cortex GABAergic interneuron migration(GO:0021853) interneuron migration(GO:1904936)
0.4 2.1 GO:0007021 tubulin complex assembly(GO:0007021)
0.3 1.4 GO:0046391 5-phosphoribose 1-diphosphate biosynthetic process(GO:0006015) 5-phosphoribose 1-diphosphate metabolic process(GO:0046391)
0.3 1.0 GO:0032242 regulation of nucleoside transport(GO:0032242) negative regulation of circadian sleep/wake cycle, non-REM sleep(GO:0042323) negative regulation of mucus secretion(GO:0070256)
0.3 1.0 GO:1905072 detection of oxygen(GO:0003032) cardiac jelly development(GO:1905072)
0.3 1.2 GO:0042138 meiotic DNA double-strand break formation(GO:0042138)
0.3 0.9 GO:0010512 negative regulation of phosphatidylinositol biosynthetic process(GO:0010512)
0.3 0.8 GO:2000331 regulation of terminal button organization(GO:2000331)
0.3 1.1 GO:0086046 membrane depolarization during SA node cell action potential(GO:0086046)
0.3 0.8 GO:0044339 canonical Wnt signaling pathway involved in osteoblast differentiation(GO:0044339)
0.3 1.5 GO:0070294 renal sodium ion absorption(GO:0070294)
0.2 1.5 GO:0014053 negative regulation of gamma-aminobutyric acid secretion(GO:0014053)
0.2 1.7 GO:0009449 gamma-aminobutyric acid biosynthetic process(GO:0009449)
0.2 0.7 GO:0035880 embryonic nail plate morphogenesis(GO:0035880)
0.2 0.9 GO:0098912 smooth muscle contraction involved in micturition(GO:0060083) membrane depolarization during atrial cardiac muscle cell action potential(GO:0098912)
0.2 2.2 GO:0015838 proline transport(GO:0015824) amino-acid betaine transport(GO:0015838)
0.2 0.9 GO:0010808 positive regulation of synaptic vesicle priming(GO:0010808)
0.2 1.3 GO:0098909 regulation of cardiac muscle cell action potential involved in regulation of contraction(GO:0098909)
0.2 0.7 GO:1903903 striated muscle atrophy(GO:0014891) positive regulation of keratinocyte apoptotic process(GO:1902174) regulation of establishment of T cell polarity(GO:1903903)
0.2 3.7 GO:0001553 luteinization(GO:0001553)
0.2 0.6 GO:2000987 positive regulation of fear response(GO:1903367) positive regulation of behavioral fear response(GO:2000987)
0.2 1.7 GO:0071372 cellular response to follicle-stimulating hormone stimulus(GO:0071372)
0.2 1.0 GO:1900748 positive regulation of vascular endothelial growth factor signaling pathway(GO:1900748)
0.2 1.0 GO:1905150 regulation of voltage-gated sodium channel activity(GO:1905150)
0.2 1.6 GO:0034975 protein folding in endoplasmic reticulum(GO:0034975)
0.2 1.0 GO:0071688 striated muscle myosin thick filament assembly(GO:0071688)
0.2 1.9 GO:0030322 stabilization of membrane potential(GO:0030322)
0.2 1.1 GO:0006452 translational frameshifting(GO:0006452) positive regulation of translational termination(GO:0045905)
0.2 1.1 GO:0048597 post-embryonic camera-type eye morphogenesis(GO:0048597)
0.2 0.7 GO:0046487 glyoxylate metabolic process(GO:0046487)
0.2 2.7 GO:0006883 cellular sodium ion homeostasis(GO:0006883)
0.2 0.5 GO:2000312 regulation of kainate selective glutamate receptor activity(GO:2000312)
0.2 0.5 GO:0002408 myeloid dendritic cell chemotaxis(GO:0002408)
0.1 1.6 GO:0045741 positive regulation of epidermal growth factor-activated receptor activity(GO:0045741)
0.1 0.3 GO:0036292 DNA rewinding(GO:0036292)
0.1 0.6 GO:0060025 regulation of synaptic activity(GO:0060025)
0.1 0.6 GO:0072069 DCT cell differentiation(GO:0072069) metanephric DCT cell differentiation(GO:0072240)
0.1 1.9 GO:0021902 commitment of neuronal cell to specific neuron type in forebrain(GO:0021902)
0.1 0.4 GO:1903722 regulation of centriole elongation(GO:1903722)
0.1 1.0 GO:0030579 ubiquitin-dependent SMAD protein catabolic process(GO:0030579)
0.1 1.1 GO:0000050 urea cycle(GO:0000050) urea metabolic process(GO:0019627)
0.1 0.9 GO:0007342 fusion of sperm to egg plasma membrane(GO:0007342)
0.1 0.8 GO:0034393 positive regulation of smooth muscle cell apoptotic process(GO:0034393) follicle-stimulating hormone signaling pathway(GO:0042699)
0.1 1.2 GO:0006686 sphingomyelin biosynthetic process(GO:0006686)
0.1 0.4 GO:0045204 MAPK export from nucleus(GO:0045204)
0.1 0.6 GO:1904721 regulation of mRNA cleavage(GO:0031437) negative regulation of mRNA cleavage(GO:0031438) negative regulation of immunoglobulin secretion(GO:0051025) regulation of mRNA endonucleolytic cleavage involved in unfolded protein response(GO:1904720) negative regulation of mRNA endonucleolytic cleavage involved in unfolded protein response(GO:1904721)
0.1 0.3 GO:2000812 regulation of barbed-end actin filament capping(GO:2000812)
0.1 0.5 GO:0019276 UDP-N-acetylgalactosamine metabolic process(GO:0019276)
0.1 0.6 GO:0021914 negative regulation of smoothened signaling pathway involved in ventral spinal cord patterning(GO:0021914)
0.1 0.3 GO:0006167 AMP biosynthetic process(GO:0006167)
0.1 0.4 GO:0061743 motor learning(GO:0061743)
0.1 0.5 GO:1903587 negative regulation of peptidyl-serine dephosphorylation(GO:1902309) regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis(GO:1903587)
0.1 2.2 GO:0042092 type 2 immune response(GO:0042092)
0.1 0.4 GO:0000957 mitochondrial RNA catabolic process(GO:0000957) regulation of mitochondrial RNA catabolic process(GO:0000960)
0.1 0.6 GO:1903056 positive regulation of lens fiber cell differentiation(GO:1902748) regulation of melanosome organization(GO:1903056)
0.1 0.2 GO:0019676 ammonia assimilation cycle(GO:0019676)
0.1 1.3 GO:0008272 sulfate transport(GO:0008272)
0.1 1.0 GO:0042572 retinol metabolic process(GO:0042572)
0.1 3.4 GO:0000038 very long-chain fatty acid metabolic process(GO:0000038)
0.1 0.3 GO:0048633 positive regulation of skeletal muscle tissue growth(GO:0048633)
0.1 0.3 GO:0001180 transcription initiation from RNA polymerase I promoter for nuclear large rRNA transcript(GO:0001180)
0.1 0.7 GO:0001574 ganglioside biosynthetic process(GO:0001574) lipid glycosylation(GO:0030259)
0.1 0.3 GO:0070197 meiotic telomere tethering at nuclear periphery(GO:0044821) meiotic attachment of telomere to nuclear envelope(GO:0070197) chromosome attachment to the nuclear envelope(GO:0097240)
0.1 0.7 GO:0044539 long-chain fatty acid import(GO:0044539)
0.1 0.6 GO:0060124 positive regulation of growth hormone secretion(GO:0060124)
0.1 5.7 GO:0048663 neuron fate commitment(GO:0048663)
0.1 0.6 GO:0033564 anterior/posterior axon guidance(GO:0033564)
0.1 0.4 GO:0032534 regulation of microvillus assembly(GO:0032534)
0.1 1.8 GO:0014067 negative regulation of phosphatidylinositol 3-kinase signaling(GO:0014067)
0.1 0.4 GO:0097167 circadian regulation of translation(GO:0097167)
0.1 1.9 GO:0008340 determination of adult lifespan(GO:0008340)
0.1 0.7 GO:0031118 rRNA pseudouridine synthesis(GO:0031118)
0.1 0.5 GO:0019348 dolichol metabolic process(GO:0019348)
0.1 0.3 GO:0046967 cytosol to ER transport(GO:0046967)
0.1 0.2 GO:0045950 negative regulation of mitotic recombination(GO:0045950) negative regulation of DNA recombination at telomere(GO:0048239) regulation of DNA recombination at telomere(GO:0072695)
0.1 0.1 GO:0010726 positive regulation of hydrogen peroxide metabolic process(GO:0010726)
0.1 0.7 GO:1900121 negative regulation of receptor binding(GO:1900121)
0.1 0.4 GO:0006498 N-terminal protein lipidation(GO:0006498)
0.1 0.3 GO:0006741 NADP biosynthetic process(GO:0006741)
0.1 0.3 GO:0061086 negative regulation of histone H3-K27 methylation(GO:0061086) chromatin maintenance(GO:0070827)
0.1 0.8 GO:0097119 postsynaptic density protein 95 clustering(GO:0097119)
0.1 0.2 GO:0090472 dibasic protein processing(GO:0090472)
0.1 0.4 GO:0071397 cellular response to cholesterol(GO:0071397)
0.1 0.3 GO:0032796 uropod organization(GO:0032796)
0.1 0.2 GO:0072014 proximal tubule development(GO:0072014)
0.1 0.2 GO:1904742 regulation of telomeric DNA binding(GO:1904742)
0.1 0.6 GO:0051601 exocyst localization(GO:0051601)
0.0 0.2 GO:0021940 positive regulation of cerebellar granule cell precursor proliferation(GO:0021940)
0.0 0.1 GO:0046077 dUDP biosynthetic process(GO:0006227) pyrimidine nucleoside diphosphate metabolic process(GO:0009138) pyrimidine nucleoside diphosphate biosynthetic process(GO:0009139) pyrimidine deoxyribonucleoside diphosphate metabolic process(GO:0009196) pyrimidine deoxyribonucleoside diphosphate biosynthetic process(GO:0009197) dUDP metabolic process(GO:0046077)
0.0 1.6 GO:0007520 myoblast fusion(GO:0007520)
0.0 0.1 GO:1900623 regulation of monocyte aggregation(GO:1900623) positive regulation of monocyte aggregation(GO:1900625)
0.0 0.1 GO:0098928 presynaptic signal transduction(GO:0098928) presynapse to nucleus signaling pathway(GO:0099526)
0.0 0.4 GO:0030539 male genitalia development(GO:0030539)
0.0 0.3 GO:0006703 estrogen biosynthetic process(GO:0006703)
0.0 0.1 GO:0006533 aspartate catabolic process(GO:0006533) D-amino acid metabolic process(GO:0046416)
0.0 1.1 GO:0009954 proximal/distal pattern formation(GO:0009954)
0.0 0.3 GO:2000398 regulation of T cell differentiation in thymus(GO:0033081) regulation of thymocyte aggregation(GO:2000398)
0.0 0.6 GO:0007130 synaptonemal complex assembly(GO:0007130)
0.0 0.2 GO:0010961 cellular magnesium ion homeostasis(GO:0010961)
0.0 1.7 GO:0097031 NADH dehydrogenase complex assembly(GO:0010257) mitochondrial respiratory chain complex I assembly(GO:0032981) mitochondrial respiratory chain complex I biogenesis(GO:0097031)
0.0 0.3 GO:0038033 positive regulation of endothelial cell chemotaxis by VEGF-activated vascular endothelial growth factor receptor signaling pathway(GO:0038033)
0.0 0.1 GO:0090309 positive regulation of methylation-dependent chromatin silencing(GO:0090309)
0.0 0.6 GO:0048305 immunoglobulin secretion(GO:0048305)
0.0 0.6 GO:0001516 prostaglandin biosynthetic process(GO:0001516) prostanoid biosynthetic process(GO:0046457)
0.0 0.3 GO:0070389 chaperone cofactor-dependent protein refolding(GO:0070389)
0.0 0.1 GO:0001978 regulation of systemic arterial blood pressure by carotid sinus baroreceptor feedback(GO:0001978)
0.0 0.3 GO:0060732 positive regulation of inositol phosphate biosynthetic process(GO:0060732)
0.0 0.4 GO:0097011 cellular response to granulocyte macrophage colony-stimulating factor stimulus(GO:0097011)
0.0 0.3 GO:2001197 regulation of basement membrane assembly involved in embryonic body morphogenesis(GO:1904259) positive regulation of basement membrane assembly involved in embryonic body morphogenesis(GO:1904261) basement membrane assembly involved in embryonic body morphogenesis(GO:2001197)
0.0 0.8 GO:0000413 protein peptidyl-prolyl isomerization(GO:0000413)
0.0 0.1 GO:1903898 positive regulation of translation in response to endoplasmic reticulum stress(GO:0036493) negative regulation of PERK-mediated unfolded protein response(GO:1903898)
0.0 0.2 GO:0051045 negative regulation of membrane protein ectodomain proteolysis(GO:0051045)
0.0 0.7 GO:0033198 response to ATP(GO:0033198)
0.0 0.5 GO:0034389 lipid particle organization(GO:0034389)
0.0 0.6 GO:0099517 anterograde synaptic vesicle transport(GO:0048490) synaptic vesicle cytoskeletal transport(GO:0099514) synaptic vesicle transport along microtubule(GO:0099517)
0.0 0.6 GO:0097320 membrane tubulation(GO:0097320)
0.0 0.2 GO:0090050 positive regulation of cell migration involved in sprouting angiogenesis(GO:0090050)
0.0 0.2 GO:0050882 voluntary musculoskeletal movement(GO:0050882)
0.0 0.1 GO:1903028 regulation of opsonization(GO:1903027) positive regulation of opsonization(GO:1903028)
0.0 0.4 GO:1903861 positive regulation of dendrite extension(GO:1903861)
0.0 0.1 GO:0007256 activation of JNKK activity(GO:0007256)
0.0 0.8 GO:0034243 regulation of transcription elongation from RNA polymerase II promoter(GO:0034243)
0.0 1.8 GO:0072583 clathrin-mediated endocytosis(GO:0072583)
0.0 0.3 GO:0032418 lysosome localization(GO:0032418)
0.0 0.1 GO:1902775 mitochondrial large ribosomal subunit assembly(GO:1902775)
0.0 0.3 GO:0019430 removal of superoxide radicals(GO:0019430)
0.0 0.2 GO:1900745 positive regulation of p38MAPK cascade(GO:1900745)
0.0 0.9 GO:0030216 keratinocyte differentiation(GO:0030216)
0.0 0.0 GO:0021523 somatic motor neuron differentiation(GO:0021523)
0.0 0.1 GO:1900042 positive regulation of interleukin-2 secretion(GO:1900042)
0.0 0.1 GO:0043974 histone H3-K27 acetylation(GO:0043974) regulation of histone H3-K27 acetylation(GO:1901674)
0.0 0.8 GO:0010501 RNA secondary structure unwinding(GO:0010501)
0.0 0.1 GO:2000507 positive regulation of energy homeostasis(GO:2000507)
0.0 0.4 GO:0032011 ARF protein signal transduction(GO:0032011) regulation of ARF protein signal transduction(GO:0032012)
0.0 0.6 GO:0006779 porphyrin-containing compound biosynthetic process(GO:0006779)
0.0 0.8 GO:0070373 negative regulation of ERK1 and ERK2 cascade(GO:0070373)
0.0 0.1 GO:0015868 purine ribonucleotide transport(GO:0015868)
0.0 0.5 GO:0021799 cerebral cortex radially oriented cell migration(GO:0021799)
0.0 0.3 GO:0052646 alditol phosphate metabolic process(GO:0052646)
0.0 0.2 GO:0005980 polysaccharide catabolic process(GO:0000272) glycogen catabolic process(GO:0005980) glucan catabolic process(GO:0009251) cellular polysaccharide catabolic process(GO:0044247)
0.0 0.2 GO:0035024 negative regulation of Rho protein signal transduction(GO:0035024)
0.0 0.7 GO:0050729 positive regulation of inflammatory response(GO:0050729)
0.0 0.2 GO:1901898 regulation of cell communication by electrical coupling involved in cardiac conduction(GO:1901844) negative regulation of relaxation of cardiac muscle(GO:1901898)
0.0 0.4 GO:2000785 regulation of autophagosome assembly(GO:2000785)
0.0 0.2 GO:0072348 sulfur compound transport(GO:0072348)
0.0 0.5 GO:0070534 protein K63-linked ubiquitination(GO:0070534)
0.0 0.2 GO:0042407 cristae formation(GO:0042407)
0.0 0.1 GO:0036265 RNA (guanine-N7)-methylation(GO:0036265)
0.0 0.2 GO:0006828 manganese ion transport(GO:0006828)
0.0 0.5 GO:0048384 retinoic acid receptor signaling pathway(GO:0048384)
0.0 0.0 GO:0043985 histone H4-R3 methylation(GO:0043985)
0.0 0.2 GO:0010107 potassium ion import(GO:0010107)
0.0 0.4 GO:1903078 positive regulation of protein localization to plasma membrane(GO:1903078)
0.0 0.2 GO:0032469 endoplasmic reticulum calcium ion homeostasis(GO:0032469)
0.0 0.3 GO:0090083 regulation of inclusion body assembly(GO:0090083)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
1.6 4.7 GO:0097058 CRLF-CLCF1 complex(GO:0097058)
0.7 10.0 GO:1902711 GABA-A receptor complex(GO:1902711)
0.6 3.1 GO:1903440 calcitonin family receptor complex(GO:1903439) amylin receptor complex(GO:1903440)
0.6 1.8 GO:0034363 intermediate-density lipoprotein particle(GO:0034363)
0.4 2.4 GO:0097512 cardiac myofibril(GO:0097512)
0.4 1.1 GO:0036488 CHOP-C/EBP complex(GO:0036488)
0.3 1.0 GO:0045160 myosin I complex(GO:0045160)
0.3 1.2 GO:0002189 ribose phosphate diphosphokinase complex(GO:0002189)
0.3 1.5 GO:0038039 G-protein coupled receptor heterodimeric complex(GO:0038039)
0.3 1.0 GO:0042627 chylomicron(GO:0042627)
0.2 2.4 GO:0048787 presynaptic active zone membrane(GO:0048787)
0.2 1.0 GO:0098831 presynaptic active zone cytoplasmic component(GO:0098831)
0.2 2.0 GO:1990454 L-type voltage-gated calcium channel complex(GO:1990454)
0.2 2.0 GO:0030130 clathrin coat of trans-Golgi network vesicle(GO:0030130)
0.2 1.0 GO:0005859 muscle myosin complex(GO:0005859)
0.2 0.6 GO:0032280 symmetric synapse(GO:0032280)
0.1 1.9 GO:0097542 ciliary tip(GO:0097542)
0.1 0.6 GO:1990769 proximal neuron projection(GO:1990769)
0.1 8.8 GO:0009925 basal plasma membrane(GO:0009925)
0.1 0.5 GO:0033185 dolichol-phosphate-mannose synthase complex(GO:0033185)
0.1 0.8 GO:0033588 Elongator holoenzyme complex(GO:0033588)
0.1 1.2 GO:0000138 Golgi trans cisterna(GO:0000138)
0.1 1.6 GO:0072546 ER membrane protein complex(GO:0072546)
0.1 1.1 GO:0005642 annulate lamellae(GO:0005642)
0.1 2.5 GO:0060077 inhibitory synapse(GO:0060077)
0.1 2.2 GO:0045178 basal part of cell(GO:0045178)
0.1 0.6 GO:0000322 storage vacuole(GO:0000322)
0.1 0.7 GO:0097197 tetraspanin-enriched microdomain(GO:0097197)
0.1 0.3 GO:0008282 ATP-sensitive potassium channel complex(GO:0008282)
0.1 0.3 GO:0032777 Piccolo NuA4 histone acetyltransferase complex(GO:0032777)
0.1 2.5 GO:0080008 Cul4-RING E3 ubiquitin ligase complex(GO:0080008)
0.1 0.6 GO:0014731 spectrin-associated cytoskeleton(GO:0014731)
0.1 1.0 GO:0031229 integral component of nuclear inner membrane(GO:0005639) intrinsic component of nuclear inner membrane(GO:0031229)
0.1 0.3 GO:0099524 region of cytosol(GO:0099522) postsynaptic cytosol(GO:0099524)
0.1 1.0 GO:0032279 asymmetric synapse(GO:0032279)
0.1 0.3 GO:0000120 RNA polymerase I transcription factor complex(GO:0000120)
0.0 0.8 GO:0031143 pseudopodium(GO:0031143)
0.0 2.1 GO:0032420 stereocilium(GO:0032420)
0.0 0.2 GO:1990604 IRE1-TRAF2-ASK1 complex(GO:1990604)
0.0 1.5 GO:0032391 photoreceptor connecting cilium(GO:0032391)
0.0 0.2 GO:0097447 dendritic tree(GO:0097447)
0.0 0.3 GO:0071818 BAT3 complex(GO:0071818) ER membrane insertion complex(GO:0072379)
0.0 0.2 GO:0012510 trans-Golgi network transport vesicle membrane(GO:0012510)
0.0 2.3 GO:0016324 apical plasma membrane(GO:0016324)
0.0 0.4 GO:0000815 ESCRT III complex(GO:0000815)
0.0 0.3 GO:0042825 TAP complex(GO:0042825)
0.0 0.4 GO:0044294 dendritic growth cone(GO:0044294)
0.0 1.7 GO:0045271 mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
0.0 0.6 GO:0001891 phagocytic cup(GO:0001891)
0.0 0.6 GO:0000145 exocyst(GO:0000145)
0.0 0.2 GO:0030870 Mre11 complex(GO:0030870)
0.0 0.3 GO:0072687 meiotic spindle(GO:0072687)
0.0 0.3 GO:0043240 Fanconi anaemia nuclear complex(GO:0043240)
0.0 0.4 GO:0034045 pre-autophagosomal structure membrane(GO:0034045)
0.0 0.9 GO:0046658 anchored component of plasma membrane(GO:0046658)
0.0 0.3 GO:0030057 desmosome(GO:0030057)
0.0 0.1 GO:0090661 box H/ACA telomerase RNP complex(GO:0090661)
0.0 2.2 GO:0030175 filopodium(GO:0030175)
0.0 0.7 GO:0030687 preribosome, large subunit precursor(GO:0030687)
0.0 0.2 GO:0071598 neuronal ribonucleoprotein granule(GO:0071598)
0.0 0.5 GO:0098839 postsynaptic density membrane(GO:0098839) postsynaptic specialization membrane(GO:0099634)
0.0 0.2 GO:0030478 actin cap(GO:0030478)
0.0 0.2 GO:0061617 MICOS complex(GO:0061617)
0.0 0.1 GO:0032437 cuticular plate(GO:0032437)
0.0 2.2 GO:0043204 perikaryon(GO:0043204)
0.0 0.9 GO:0005801 cis-Golgi network(GO:0005801)
0.0 0.9 GO:0005902 microvillus(GO:0005902) actin-based cell projection(GO:0098858)
0.0 0.8 GO:0030173 integral component of Golgi membrane(GO:0030173)
0.0 3.8 GO:0098852 lysosomal membrane(GO:0005765) lytic vacuole membrane(GO:0098852)
0.0 0.1 GO:0043527 tRNA methyltransferase complex(GO:0043527)
0.0 0.3 GO:0035327 transcriptionally active chromatin(GO:0035327)
0.0 0.2 GO:0005751 mitochondrial respiratory chain complex IV(GO:0005751)
0.0 2.6 GO:0005777 peroxisome(GO:0005777) microbody(GO:0042579)
0.0 3.5 GO:0043235 receptor complex(GO:0043235)
0.0 1.1 GO:0032587 ruffle membrane(GO:0032587)
0.0 0.2 GO:0031902 late endosome membrane(GO:0031902)
0.0 0.6 GO:0045171 intercellular bridge(GO:0045171)
0.0 0.1 GO:0016281 eukaryotic translation initiation factor 4F complex(GO:0016281)
0.0 0.2 GO:0030285 integral component of synaptic vesicle membrane(GO:0030285) intrinsic component of synaptic vesicle membrane(GO:0098563)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
2.4 9.8 GO:0005008 hepatocyte growth factor-activated receptor activity(GO:0005008)
1.1 6.4 GO:0022851 GABA-gated chloride ion channel activity(GO:0022851)
0.8 2.4 GO:0070905 serine binding(GO:0070905)
0.7 2.8 GO:0005111 type 2 fibroblast growth factor receptor binding(GO:0005111)
0.7 4.7 GO:0005127 ciliary neurotrophic factor receptor binding(GO:0005127)
0.6 3.1 GO:0097643 amylin receptor activity(GO:0097643)
0.6 1.8 GO:0046911 hydroxyapatite binding(GO:0046848) metal chelating activity(GO:0046911) phosphatidylcholine-sterol O-acyltransferase activator activity(GO:0060228)
0.5 4.9 GO:0036122 BMP binding(GO:0036122)
0.5 2.0 GO:2001069 glycogen binding(GO:2001069)
0.4 2.9 GO:0015379 potassium:chloride symporter activity(GO:0015379) potassium ion symporter activity(GO:0022820)
0.3 1.2 GO:0004749 ribose phosphate diphosphokinase activity(GO:0004749)
0.3 3.5 GO:0004890 GABA-A receptor activity(GO:0004890)
0.3 1.2 GO:0061505 DNA topoisomerase type II (ATP-hydrolyzing) activity(GO:0003918) DNA topoisomerase II activity(GO:0061505)
0.3 3.2 GO:0031957 very long-chain fatty acid-CoA ligase activity(GO:0031957)
0.3 2.2 GO:0015193 L-proline transmembrane transporter activity(GO:0015193)
0.3 1.9 GO:0004351 glutamate decarboxylase activity(GO:0004351)
0.3 0.8 GO:0031896 V2 vasopressin receptor binding(GO:0031896)
0.2 2.0 GO:0086007 voltage-gated calcium channel activity involved in cardiac muscle cell action potential(GO:0086007)
0.2 1.5 GO:0004965 G-protein coupled GABA receptor activity(GO:0004965)
0.2 0.7 GO:0043758 acetate-CoA ligase (ADP-forming) activity(GO:0043758)
0.2 1.2 GO:0033188 sphingomyelin synthase activity(GO:0033188) ceramide cholinephosphotransferase activity(GO:0047493)
0.2 0.7 GO:0008192 RNA guanylyltransferase activity(GO:0008192)
0.2 1.7 GO:0005004 GPI-linked ephrin receptor activity(GO:0005004)
0.2 1.0 GO:0051371 muscle alpha-actinin binding(GO:0051371)
0.2 0.7 GO:0016833 oxo-acid-lyase activity(GO:0016833)
0.2 0.5 GO:0003986 acetyl-CoA hydrolase activity(GO:0003986)
0.2 1.9 GO:0022841 potassium ion leak channel activity(GO:0022841)
0.2 2.0 GO:0032050 clathrin heavy chain binding(GO:0032050)
0.2 1.4 GO:0005212 structural constituent of eye lens(GO:0005212)
0.2 1.1 GO:0005021 vascular endothelial growth factor-activated receptor activity(GO:0005021)
0.2 0.5 GO:0001888 glucuronyl-galactosyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity(GO:0001888)
0.1 1.0 GO:0001609 G-protein coupled adenosine receptor activity(GO:0001609)
0.1 1.0 GO:0052650 NADP-retinol dehydrogenase activity(GO:0052650)
0.1 0.5 GO:0004582 dolichyl-phosphate beta-D-mannosyltransferase activity(GO:0004582)
0.1 1.0 GO:0048495 Roundabout binding(GO:0048495)
0.1 1.7 GO:0048038 quinone binding(GO:0048038)
0.1 0.3 GO:0004711 ribosomal protein S6 kinase activity(GO:0004711)
0.1 0.7 GO:0035381 extracellular ATP-gated cation channel activity(GO:0004931) ATP-gated ion channel activity(GO:0035381)
0.1 0.7 GO:0045545 syndecan binding(GO:0045545)
0.1 3.2 GO:0043539 protein serine/threonine kinase activator activity(GO:0043539)
0.1 0.4 GO:0008184 glycogen phosphorylase activity(GO:0008184)
0.1 2.3 GO:0003950 NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.1 0.4 GO:0005113 patched binding(GO:0005113)
0.1 0.6 GO:0005042 netrin receptor activity(GO:0005042)
0.1 0.6 GO:0060698 endoribonuclease inhibitor activity(GO:0060698)
0.1 0.6 GO:0001515 opioid peptide activity(GO:0001515)
0.1 0.4 GO:0004609 phosphatidylserine decarboxylase activity(GO:0004609)
0.1 1.0 GO:0004806 triglyceride lipase activity(GO:0004806)
0.1 1.0 GO:0030898 actin-dependent ATPase activity(GO:0030898)
0.1 1.1 GO:0017070 U6 snRNA binding(GO:0017070)
0.1 0.2 GO:0035939 microsatellite binding(GO:0035939)
0.1 0.3 GO:0015433 peptide antigen-transporting ATPase activity(GO:0015433) tapasin binding(GO:0046980)
0.1 0.5 GO:0019870 potassium channel inhibitor activity(GO:0019870)
0.1 0.3 GO:0070404 NADH binding(GO:0070404)
0.1 0.8 GO:0048407 platelet-derived growth factor binding(GO:0048407)
0.1 1.8 GO:0050750 low-density lipoprotein particle receptor binding(GO:0050750)
0.1 1.5 GO:0008376 acetylgalactosaminyltransferase activity(GO:0008376)
0.1 1.3 GO:0043325 phosphatidylinositol-3,4-bisphosphate binding(GO:0043325)
0.1 0.7 GO:1990459 transferrin receptor binding(GO:1990459)
0.1 2.1 GO:0017080 sodium channel regulator activity(GO:0017080)
0.1 0.5 GO:0004886 9-cis retinoic acid receptor activity(GO:0004886)
0.1 1.7 GO:0071837 HMG box domain binding(GO:0071837)
0.0 1.2 GO:0031683 G-protein beta/gamma-subunit complex binding(GO:0031683)
0.0 0.8 GO:0042043 neurexin family protein binding(GO:0042043)
0.0 0.1 GO:0009041 uridylate kinase activity(GO:0009041)
0.0 0.4 GO:0070290 phospholipase D activity(GO:0004630) N-acylphosphatidylethanolamine-specific phospholipase D activity(GO:0070290)
0.0 1.9 GO:0005544 calcium-dependent phospholipid binding(GO:0005544)
0.0 3.0 GO:0042562 hormone binding(GO:0042562)
0.0 1.2 GO:0001223 transcription coactivator binding(GO:0001223)
0.0 4.4 GO:0008201 heparin binding(GO:0008201)
0.0 0.8 GO:0005528 macrolide binding(GO:0005527) FK506 binding(GO:0005528)
0.0 0.5 GO:0043008 ATP-dependent protein binding(GO:0043008)
0.0 0.3 GO:0032036 myosin heavy chain binding(GO:0032036)
0.0 0.4 GO:0031210 phosphatidylcholine binding(GO:0031210)
0.0 0.3 GO:0000990 transcription factor activity, core RNA polymerase binding(GO:0000990)
0.0 0.1 GO:0050501 hyaluronan synthase activity(GO:0050501)
0.0 0.3 GO:0003993 acid phosphatase activity(GO:0003993)
0.0 0.1 GO:0004035 alkaline phosphatase activity(GO:0004035)
0.0 0.1 GO:0008176 tRNA (guanine-N7-)-methyltransferase activity(GO:0008176)
0.0 0.7 GO:0043236 laminin binding(GO:0043236)
0.0 0.3 GO:0015279 store-operated calcium channel activity(GO:0015279)
0.0 0.7 GO:0051117 ATPase binding(GO:0051117)
0.0 0.3 GO:0035612 AP-2 adaptor complex binding(GO:0035612)
0.0 0.8 GO:0005154 epidermal growth factor receptor binding(GO:0005154)
0.0 0.4 GO:0003774 motor activity(GO:0003774)
0.0 0.3 GO:0036310 annealing helicase activity(GO:0036310)
0.0 0.3 GO:0015643 toxic substance binding(GO:0015643)
0.0 2.6 GO:0003705 transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0003705)
0.0 0.3 GO:0016701 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen(GO:0016701) oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen(GO:0016702)
0.0 0.4 GO:0005540 hyaluronic acid binding(GO:0005540)
0.0 0.2 GO:0004467 long-chain fatty acid-CoA ligase activity(GO:0004467) decanoate--CoA ligase activity(GO:0102391)
0.0 0.2 GO:0003964 telomerase activity(GO:0003720) RNA-directed DNA polymerase activity(GO:0003964)
0.0 0.2 GO:0048406 nerve growth factor binding(GO:0048406)
0.0 0.3 GO:0035925 mRNA 3'-UTR AU-rich region binding(GO:0035925)
0.0 0.3 GO:0001134 transcription factor activity, transcription factor recruiting(GO:0001134)
0.0 0.5 GO:0030276 clathrin binding(GO:0030276)
0.0 0.2 GO:0036312 phosphatidylinositol 3-kinase regulatory subunit binding(GO:0036312)
0.0 0.8 GO:0035064 methylated histone binding(GO:0035064)
0.0 0.1 GO:0034513 box H/ACA snoRNA binding(GO:0034513)
0.0 0.7 GO:0005246 calcium channel regulator activity(GO:0005246)
0.0 0.4 GO:0042605 peptide antigen binding(GO:0042605)
0.0 0.2 GO:0009922 fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338)
0.0 0.3 GO:0003951 NAD+ kinase activity(GO:0003951)
0.0 0.6 GO:0019239 deaminase activity(GO:0019239)
0.0 1.0 GO:0003743 translation initiation factor activity(GO:0003743)
0.0 0.2 GO:0005328 neurotransmitter:sodium symporter activity(GO:0005328)
0.0 0.7 GO:0015459 potassium channel regulator activity(GO:0015459)
0.0 0.5 GO:0035255 ionotropic glutamate receptor binding(GO:0035255)
0.0 0.7 GO:0017022 myosin binding(GO:0017022)
0.0 0.4 GO:0005086 ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.0 0.9 GO:0005262 calcium channel activity(GO:0005262)
0.0 0.1 GO:0005243 gap junction channel activity(GO:0005243)
0.0 0.2 GO:0016709 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen(GO:0016709)
0.0 1.3 GO:0005089 Rho guanyl-nucleotide exchange factor activity(GO:0005089)
0.0 0.2 GO:0015095 magnesium ion transmembrane transporter activity(GO:0015095)
0.0 0.2 GO:0004709 MAP kinase kinase kinase activity(GO:0004709)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 10.1 PID_ARF6_PATHWAY Arf6 signaling events
0.1 1.4 PID_ERBB_NETWORK_PATHWAY ErbB receptor signaling network
0.1 1.1 PID_VEGF_VEGFR_PATHWAY VEGF and VEGFR signaling network
0.1 13.3 NABA_SECRETED_FACTORS Genes encoding secreted soluble factors
0.1 2.1 NABA_BASEMENT_MEMBRANES Genes encoding structural components of basement membranes
0.1 1.6 PID_ARF_3PATHWAY Arf1 pathway
0.0 1.6 PID_NECTIN_PATHWAY Nectin adhesion pathway
0.0 1.3 ST_GA12_PATHWAY G alpha 12 Pathway
0.0 1.8 PID_LYSOPHOSPHOLIPID_PATHWAY LPA receptor mediated events
0.0 1.8 PID_A6B1_A6B4_INTEGRIN_PATHWAY a6b1 and a6b4 Integrin signaling
0.0 1.0 PID_EPHA_FWDPATHWAY EPHA forward signaling
0.0 0.7 PID_AVB3_OPN_PATHWAY Osteopontin-mediated events
0.0 1.2 PID_PI3KCI_PATHWAY Class I PI3K signaling events
0.0 1.0 PID_ALK1_PATHWAY ALK1 signaling events
0.0 1.2 PID_IL2_PI3K_PATHWAY IL2 signaling events mediated by PI3K
0.0 2.3 PID_HEDGEHOG_GLI_PATHWAY Hedgehog signaling events mediated by Gli proteins
0.0 0.8 PID_AURORA_A_PATHWAY Aurora A signaling
0.0 0.3 PID_ALPHA_SYNUCLEIN_PATHWAY Alpha-synuclein signaling
0.0 0.4 PID_CIRCADIAN_PATHWAY Circadian rhythm pathway
0.0 0.1 PID_WNT_NONCANONICAL_PATHWAY Noncanonical Wnt signaling pathway
0.0 0.6 PID_BMP_PATHWAY BMP receptor signaling
0.0 0.4 NABA_COLLAGENS Genes encoding collagen proteins
0.0 1.6 NABA_ECM_GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.0 0.8 PID_MYC_REPRESS_PATHWAY Validated targets of C-MYC transcriptional repression
0.0 0.4 PID_HNF3A_PATHWAY FOXA1 transcription factor network

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 10.0 REACTOME_GABA_A_RECEPTOR_ACTIVATION Genes involved in GABA A receptor activation
0.3 3.8 REACTOME_CLASS_C_3_METABOTROPIC_GLUTAMATE_PHEROMONE_RECEPTORS Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors)
0.3 1.9 REACTOME_TANDEM_PORE_DOMAIN_POTASSIUM_CHANNELS Genes involved in Tandem pore domain potassium channels
0.2 9.7 REACTOME_SEMA4D_IN_SEMAPHORIN_SIGNALING Genes involved in Sema4D in semaphorin signaling
0.2 2.8 REACTOME_FGFR1_LIGAND_BINDING_AND_ACTIVATION Genes involved in FGFR1 ligand binding and activation
0.2 2.9 REACTOME_CHYLOMICRON_MEDIATED_LIPID_TRANSPORT Genes involved in Chylomicron-mediated lipid transport
0.1 3.1 REACTOME_GABA_SYNTHESIS_RELEASE_REUPTAKE_AND_DEGRADATION Genes involved in GABA synthesis, release, reuptake and degradation
0.1 2.0 REACTOME_GAP_JUNCTION_DEGRADATION Genes involved in Gap junction degradation
0.1 1.1 REACTOME_VEGF_LIGAND_RECEPTOR_INTERACTIONS Genes involved in VEGF ligand-receptor interactions
0.1 0.5 REACTOME_ELEVATION_OF_CYTOSOLIC_CA2_LEVELS Genes involved in Elevation of cytosolic Ca2+ levels
0.1 1.0 REACTOME_NUCLEOTIDE_LIKE_PURINERGIC_RECEPTORS Genes involved in Nucleotide-like (purinergic) receptors
0.1 1.3 REACTOME_PTM_GAMMA_CARBOXYLATION_HYPUSINE_FORMATION_AND_ARYLSULFATASE_ACTIVATION Genes involved in PTM: gamma carboxylation, hypusine formation and arylsulfatase activation
0.0 1.6 REACTOME_ADHERENS_JUNCTIONS_INTERACTIONS Genes involved in Adherens junctions interactions
0.0 1.4 REACTOME_MYOGENESIS Genes involved in Myogenesis
0.0 0.9 REACTOME_ALPHA_LINOLENIC_ACID_ALA_METABOLISM Genes involved in alpha-linolenic acid (ALA) metabolism
0.0 0.5 REACTOME_ROLE_OF_DCC_IN_REGULATING_APOPTOSIS Genes involved in Role of DCC in regulating apoptosis
0.0 0.6 REACTOME_METABOLISM_OF_POLYAMINES Genes involved in Metabolism of polyamines
0.0 0.6 REACTOME_POST_CHAPERONIN_TUBULIN_FOLDING_PATHWAY Genes involved in Post-chaperonin tubulin folding pathway
0.0 0.3 REACTOME_MTORC1_MEDIATED_SIGNALLING Genes involved in mTORC1-mediated signalling
0.0 0.4 REACTOME_BMAL1_CLOCK_NPAS2_ACTIVATES_CIRCADIAN_EXPRESSION Genes involved in BMAL1:CLOCK/NPAS2 Activates Circadian Expression
0.0 3.7 REACTOME_G_ALPHA_S_SIGNALLING_EVENTS Genes involved in G alpha (s) signalling events
0.0 0.9 REACTOME_DEADENYLATION_OF_MRNA Genes involved in Deadenylation of mRNA
0.0 0.5 REACTOME_SYNTHESIS_OF_SUBSTRATES_IN_N_GLYCAN_BIOSYTHESIS Genes involved in Synthesis of substrates in N-glycan biosythesis
0.0 0.7 REACTOME_CASPASE_MEDIATED_CLEAVAGE_OF_CYTOSKELETAL_PROTEINS Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.0 2.0 REACTOME_NUCLEAR_RECEPTOR_TRANSCRIPTION_PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.0 1.2 REACTOME_SPHINGOLIPID_DE_NOVO_BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis
0.0 0.7 REACTOME_LYSOSOME_VESICLE_BIOGENESIS Genes involved in Lysosome Vesicle Biogenesis
0.0 1.7 REACTOME_RESPIRATORY_ELECTRON_TRANSPORT Genes involved in Respiratory electron transport
0.0 0.2 REACTOME_NA_CL_DEPENDENT_NEUROTRANSMITTER_TRANSPORTERS Genes involved in Na+/Cl- dependent neurotransmitter transporters
0.0 0.3 REACTOME_PURINE_RIBONUCLEOSIDE_MONOPHOSPHATE_BIOSYNTHESIS Genes involved in Purine ribonucleoside monophosphate biosynthesis
0.0 1.5 REACTOME_MEIOTIC_SYNAPSIS Genes involved in Meiotic Synapsis
0.0 1.5 REACTOME_TRANSPORT_OF_INORGANIC_CATIONS_ANIONS_AND_AMINO_ACIDS_OLIGOPEPTIDES Genes involved in Transport of inorganic cations/anions and amino acids/oligopeptides
0.0 0.3 REACTOME_ANTIGEN_PRESENTATION_FOLDING_ASSEMBLY_AND_PEPTIDE_LOADING_OF_CLASS_I_MHC Genes involved in Antigen Presentation: Folding, assembly and peptide loading of class I MHC
0.0 1.1 REACTOME_RESPONSE_TO_ELEVATED_PLATELET_CYTOSOLIC_CA2_ Genes involved in Response to elevated platelet cytosolic Ca2+
0.0 0.3 REACTOME_CHOLESTEROL_BIOSYNTHESIS Genes involved in Cholesterol biosynthesis
0.0 0.2 REACTOME_INWARDLY_RECTIFYING_K_CHANNELS Genes involved in Inwardly rectifying K+ channels
0.0 0.4 REACTOME_SYNTHESIS_OF_PA Genes involved in Synthesis of PA
0.0 0.1 REACTOME_GAP_JUNCTION_TRAFFICKING Genes involved in Gap junction trafficking