Motif ID: Gmeb1
Z-value: 0.324
Transcription factors associated with Gmeb1:
Gene Symbol | Entrez ID | Gene Name |
---|---|---|
Gmeb1 | ENSMUSG00000028901.7 | Gmeb1 |
Activity-expression correlation:
Gene Symbol | Promoter | Pearson corr. coef. | P-value | Plot |
---|---|---|---|---|
Gmeb1 | mm10_v2_chr4_-_132261521_132261572 | 0.63 | 2.4e-05 | Click! |
Top targets:
Gene overrepresentation in biological_process category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.6 | 2.5 | GO:0051316 | attachment of spindle microtubules to kinetochore involved in meiotic chromosome segregation(GO:0051316) |
0.3 | 2.1 | GO:0098535 | positive regulation of centriole replication(GO:0046601) de novo centriole assembly(GO:0098535) |
0.2 | 0.7 | GO:0034241 | positive regulation of macrophage fusion(GO:0034241) |
0.2 | 1.6 | GO:2000348 | regulation of CD40 signaling pathway(GO:2000348) |
0.2 | 0.5 | GO:0046544 | regulation of natural killer cell proliferation(GO:0032817) positive regulation of natural killer cell proliferation(GO:0032819) development of secondary male sexual characteristics(GO:0046544) |
0.1 | 0.4 | GO:1904211 | membrane protein proteolysis involved in retrograde protein transport, ER to cytosol(GO:1904211) |
0.1 | 1.0 | GO:0016446 | somatic hypermutation of immunoglobulin genes(GO:0016446) |
0.1 | 1.0 | GO:0031936 | negative regulation of chromatin silencing(GO:0031936) |
0.1 | 0.4 | GO:0034196 | acylglycerol transport(GO:0034196) triglyceride transport(GO:0034197) |
0.1 | 0.3 | GO:0010825 | positive regulation of centrosome duplication(GO:0010825) |
0.1 | 0.2 | GO:0006592 | ornithine biosynthetic process(GO:0006592) |
0.0 | 1.0 | GO:0010960 | magnesium ion homeostasis(GO:0010960) |
0.0 | 0.5 | GO:0042407 | cristae formation(GO:0042407) |
0.0 | 0.1 | GO:0048633 | positive regulation of skeletal muscle tissue growth(GO:0048633) |
0.0 | 0.1 | GO:0051661 | maintenance of centrosome location(GO:0051661) |
0.0 | 0.2 | GO:0070986 | left/right axis specification(GO:0070986) |
0.0 | 0.1 | GO:0032264 | IMP salvage(GO:0032264) |
0.0 | 0.1 | GO:0061084 | negative regulation of protein refolding(GO:0061084) |
Gene overrepresentation in cellular_component category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.6 | 2.5 | GO:0000939 | nuclear MIS12/MIND complex(GO:0000818) condensed chromosome inner kinetochore(GO:0000939) |
0.4 | 2.1 | GO:0098536 | deuterosome(GO:0098536) |
0.1 | 0.5 | GO:0061617 | MICOS complex(GO:0061617) |
0.0 | 0.7 | GO:0031233 | intrinsic component of external side of plasma membrane(GO:0031233) |
0.0 | 0.4 | GO:0044322 | endoplasmic reticulum quality control compartment(GO:0044322) |
0.0 | 0.1 | GO:0043540 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase complex(GO:0043540) |
0.0 | 0.4 | GO:0031528 | microvillus membrane(GO:0031528) |
0.0 | 0.5 | GO:1990124 | messenger ribonucleoprotein complex(GO:1990124) |
0.0 | 0.3 | GO:0035102 | PRC1 complex(GO:0035102) |
0.0 | 0.1 | GO:0000235 | astral microtubule(GO:0000235) |
0.0 | 0.2 | GO:0097225 | sperm midpiece(GO:0097225) |
Gene overrepresentation in molecular_function category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.3 | 1.0 | GO:0008309 | double-stranded DNA exodeoxyribonuclease activity(GO:0008309) |
0.1 | 1.0 | GO:0009019 | tRNA (guanine-N1-)-methyltransferase activity(GO:0009019) |
0.1 | 0.5 | GO:0051032 | nucleic acid transmembrane transporter activity(GO:0051032) RNA transmembrane transporter activity(GO:0051033) |
0.1 | 1.6 | GO:0070182 | DNA polymerase binding(GO:0070182) |
0.1 | 0.2 | GO:0017084 | glutamate 5-kinase activity(GO:0004349) glutamate-5-semialdehyde dehydrogenase activity(GO:0004350) delta1-pyrroline-5-carboxylate synthetase activity(GO:0017084) amino acid kinase activity(GO:0019202) |
0.1 | 1.0 | GO:0005540 | hyaluronic acid binding(GO:0005540) |
0.0 | 0.2 | GO:0044547 | DNA topoisomerase binding(GO:0044547) |
0.0 | 0.1 | GO:0032564 | dATP binding(GO:0032564) |
0.0 | 0.1 | GO:0004711 | ribosomal protein S6 kinase activity(GO:0004711) |
0.0 | 0.7 | GO:0043236 | laminin binding(GO:0043236) |
0.0 | 0.5 | GO:0070577 | lysine-acetylated histone binding(GO:0070577) |
0.0 | 0.5 | GO:0035259 | glucocorticoid receptor binding(GO:0035259) |
0.0 | 0.1 | GO:0046920 | alpha-(1->3)-fucosyltransferase activity(GO:0046920) |
0.0 | 0.4 | GO:0034185 | apolipoprotein binding(GO:0034185) |
0.0 | 0.1 | GO:0003876 | AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623) |
0.0 | 0.1 | GO:0070095 | fructose-6-phosphate binding(GO:0070095) |
0.0 | 0.1 | GO:0017162 | aryl hydrocarbon receptor binding(GO:0017162) |
Gene overrepresentation in C2:CP category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.0 | 1.6 | PID_BARD1_PATHWAY | BARD1 signaling events |
0.0 | 0.5 | PID_IL5_PATHWAY | IL5-mediated signaling events |
Gene overrepresentation in C2:CP:REACTOME category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.2 | 1.6 | REACTOME_REGULATION_OF_THE_FANCONI_ANEMIA_PATHWAY | Genes involved in Regulation of the Fanconi anemia pathway |
0.1 | 1.0 | REACTOME_HYALURONAN_UPTAKE_AND_DEGRADATION | Genes involved in Hyaluronan uptake and degradation |
0.0 | 0.5 | REACTOME_PROLACTIN_RECEPTOR_SIGNALING | Genes involved in Prolactin receptor signaling |
0.0 | 0.4 | REACTOME_CHYLOMICRON_MEDIATED_LIPID_TRANSPORT | Genes involved in Chylomicron-mediated lipid transport |
0.0 | 1.9 | REACTOME_LOSS_OF_NLP_FROM_MITOTIC_CENTROSOMES | Genes involved in Loss of Nlp from mitotic centrosomes |
0.0 | 1.8 | REACTOME_MITOTIC_PROMETAPHASE | Genes involved in Mitotic Prometaphase |
0.0 | 0.1 | REACTOME_MTORC1_MEDIATED_SIGNALLING | Genes involved in mTORC1-mediated signalling |