Motif ID: Grhl1

Z-value: 0.350


Transcription factors associated with Grhl1:

Gene SymbolEntrez IDGene Name
Grhl1 ENSMUSG00000020656.9 Grhl1

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Grhl1mm10_v2_chr12_+_24572276_245723080.029.0e-01Click!


Activity profile for motif Grhl1.

activity profile for motif Grhl1


Sorted Z-values histogram for motif Grhl1

Sorted Z-values for motif Grhl1



Network of associatons between targets according to the STRING database.



First level regulatory network of Grhl1

PNG image of the network

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Top targets:


Showing 1 to 20 of 51 entries
PromoterScoreRefseqGene SymbolGene Name
chr3_-_85722474 1.040 ENSMUST00000119077.1
 Fam160a1
family with sequence similarity 160, member A1
chr1_-_192855723 0.632 ENSMUST00000155579.1
 Sertad4
SERTA domain containing 4
chrX_-_38456407 0.627 ENSMUST00000074913.5
ENSMUST00000016678.7
ENSMUST00000061755.8
 Lamp2


lysosomal-associated membrane protein 2


chr4_-_19570073 0.546 ENSMUST00000029885.4
 Cpne3
copine III
chr18_+_56432116 0.540 ENSMUST00000070166.5
 Gramd3
GRAM domain containing 3
chr14_-_57133268 0.520 ENSMUST00000160703.1
 Gjb6
gap junction protein, beta 6
chr17_+_87635974 0.495 ENSMUST00000053577.8
 Epcam
epithelial cell adhesion molecule
chr2_-_151973387 0.431 ENSMUST00000109863.1
 Fam110a
family with sequence similarity 110, member A
chr16_-_26989974 0.423 ENSMUST00000089832.4
 Gmnc
geminin coiled-coil domain containing
chr2_+_172550761 0.423 ENSMUST00000099058.3
 Tfap2c
transcription factor AP-2, gamma
chr14_+_79481164 0.422 ENSMUST00000040131.5
 Elf1
E74-like factor 1
chr14_+_63943666 0.396 ENSMUST00000079652.5
 Sox7
SRY-box containing gene 7
chr3_-_87263518 0.387 ENSMUST00000090986.4
 Fcrls
Fc receptor-like S, scavenger receptor
chr2_-_105399286 0.381 ENSMUST00000006128.6
 Rcn1
reticulocalbin 1
chr14_-_73385225 0.364 ENSMUST00000022704.7
 Itm2b
integral membrane protein 2B
chrX_+_100730178 0.356 ENSMUST00000113744.1
 Gdpd2
glycerophosphodiester phosphodiesterase domain containing 2
chr17_-_56005566 0.316 ENSMUST00000043785.6
 Stap2
signal transducing adaptor family member 2
chr9_+_21337828 0.309 ENSMUST00000034697.7
 Slc44a2
solute carrier family 44, member 2
chr8_-_71381907 0.307 ENSMUST00000002466.8
 Nr2f6
nuclear receptor subfamily 2, group F, member 6
chr2_-_30205772 0.292 ENSMUST00000113662.1
 Ccbl1
cysteine conjugate-beta lyase 1

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 18 of 18 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.2 0.6 GO:0071211 protein targeting to vacuole involved in autophagy(GO:0071211)
0.1 0.5 GO:0038128 ERBB2 signaling pathway(GO:0038128)
0.1 0.5 GO:2000048 negative regulation of cell-cell adhesion mediated by cadherin(GO:2000048)
0.1 0.4 GO:0060598 dichotomous subdivision of terminal units involved in mammary gland duct morphogenesis(GO:0060598)
0.1 0.4 GO:0042985 negative regulation of amyloid precursor protein biosynthetic process(GO:0042985)
0.0 0.4 GO:0090527 actin filament reorganization(GO:0090527)
0.0 0.4 GO:0050860 negative regulation of T cell receptor signaling pathway(GO:0050860)
0.0 0.4 GO:0006270 DNA replication initiation(GO:0006270)
0.0 0.4 GO:0001706 endoderm formation(GO:0001706)
0.0 0.3 GO:0032782 bile acid secretion(GO:0032782) positive regulation of peroxisome proliferator activated receptor signaling pathway(GO:0035360)
0.0 0.3 GO:0050965 detection of temperature stimulus involved in sensory perception(GO:0050961) detection of temperature stimulus involved in sensory perception of pain(GO:0050965)
0.0 0.3 GO:0051639 actin filament network formation(GO:0051639)
0.0 0.3 GO:0045292 mRNA cis splicing, via spliceosome(GO:0045292)
0.1 0.2 GO:0051771 negative regulation of nitric-oxide synthase biosynthetic process(GO:0051771)
0.0 0.2 GO:0007016 cytoskeletal anchoring at plasma membrane(GO:0007016)
0.0 0.2 GO:1902866 regulation of retina development in camera-type eye(GO:1902866)
0.0 0.2 GO:0019363 pyridine nucleotide biosynthetic process(GO:0019363)
0.0 0.1 GO:0039536 negative regulation of RIG-I signaling pathway(GO:0039536)

Gene overrepresentation in cellular_component category:

Showing 1 to 5 of 5 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.2 0.6 GO:0031088 platelet dense granule membrane(GO:0031088) intrinsic component of autophagosome membrane(GO:0097636) integral component of autophagosome membrane(GO:0097637)
0.0 0.5 GO:0005922 connexon complex(GO:0005922)
0.0 0.3 GO:0046581 intercellular canaliculus(GO:0046581)
0.0 0.3 GO:0001891 phagocytic cup(GO:0001891)
0.0 0.1 GO:0017059 serine C-palmitoyltransferase complex(GO:0017059) endoplasmic reticulum palmitoyltransferase complex(GO:0031211)

Gene overrepresentation in molecular_function category:

Showing 1 to 7 of 7 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 0.5 GO:0098641 cadherin binding involved in cell-cell adhesion(GO:0098641)
0.0 0.5 GO:0005544 calcium-dependent phospholipid binding(GO:0005544)
0.0 0.4 GO:0008889 glycerophosphodiester phosphodiesterase activity(GO:0008889)
0.0 0.2 GO:0004661 protein geranylgeranyltransferase activity(GO:0004661)
0.0 0.2 GO:0008474 palmitoyl-(protein) hydrolase activity(GO:0008474) palmitoyl hydrolase activity(GO:0098599)
0.0 0.1 GO:0004758 serine C-palmitoyltransferase activity(GO:0004758) C-palmitoyltransferase activity(GO:0016454)
0.0 0.1 GO:0019153 protein-disulfide reductase (glutathione) activity(GO:0019153)

Gene overrepresentation in C2:CP:REACTOME category:

Showing 1 to 3 of 3 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 0.6 REACTOME_TRYPTOPHAN_CATABOLISM Genes involved in Tryptophan catabolism
0.0 0.5 REACTOME_GAP_JUNCTION_ASSEMBLY Genes involved in Gap junction assembly
0.0 0.3 REACTOME_AMINE_COMPOUND_SLC_TRANSPORTERS Genes involved in Amine compound SLC transporters