Motif ID: Hbp1

Z-value: 0.531


Transcription factors associated with Hbp1:

Gene SymbolEntrez IDGene Name
Hbp1 ENSMUSG00000002996.11 Hbp1

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Hbp1mm10_v2_chr12_-_31950535_31950560-0.271.0e-01Click!


Activity profile for motif Hbp1.

activity profile for motif Hbp1


Sorted Z-values histogram for motif Hbp1

Sorted Z-values for motif Hbp1



Network of associatons between targets according to the STRING database.



First level regulatory network of Hbp1

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr7_-_79386943 2.747 ENSMUST00000053718.8
ENSMUST00000179243.1
Rlbp1

retinaldehyde binding protein 1

chr15_-_66812593 2.483 ENSMUST00000100572.3
Sla
src-like adaptor
chr13_-_66851513 2.127 ENSMUST00000169322.1
Gm17404
predicted gene, 17404
chr15_-_66801577 1.679 ENSMUST00000168589.1
Sla
src-like adaptor
chr13_-_66852017 1.672 ENSMUST00000059329.6
Gm17449
predicted gene, 17449
chr4_-_14621805 1.463 ENSMUST00000042221.7
Slc26a7
solute carrier family 26, member 7
chr3_+_121953213 1.285 ENSMUST00000037958.7
ENSMUST00000128366.1
Arhgap29

Rho GTPase activating protein 29

chr5_+_90772435 1.150 ENSMUST00000031320.6
Pf4
platelet factor 4
chr9_-_77347816 1.149 ENSMUST00000184138.1
ENSMUST00000184006.1
ENSMUST00000185144.1
ENSMUST00000034910.9
Mlip



muscular LMNA-interacting protein



chr11_-_7213897 1.105 ENSMUST00000020702.4
ENSMUST00000135887.2
Igfbp3

insulin-like growth factor binding protein 3

chr8_+_66697404 1.104 ENSMUST00000039303.5
Npy1r
neuropeptide Y receptor Y1
chr7_-_103827922 1.061 ENSMUST00000023934.6
ENSMUST00000153218.1
Hbb-bs

hemoglobin, beta adult s chain

chr3_+_68584154 1.055 ENSMUST00000182997.1
Schip1
schwannomin interacting protein 1
chrX_+_150547375 1.039 ENSMUST00000066337.6
ENSMUST00000112715.1
Alas2

aminolevulinic acid synthase 2, erythroid

chr10_+_11609256 0.951 ENSMUST00000052902.7
Gm9797
predicted pseudogene 9797
chr4_-_136898803 0.889 ENSMUST00000046285.5
C1qa
complement component 1, q subcomponent, alpha polypeptide
chr13_+_31806627 0.867 ENSMUST00000062292.2
Foxc1
forkhead box C1
chr6_-_29179584 0.809 ENSMUST00000159200.1
Prrt4
proline-rich transmembrane protein 4
chr17_+_47688992 0.790 ENSMUST00000156118.1
Frs3
fibroblast growth factor receptor substrate 3
chr11_+_101246960 0.767 ENSMUST00000107282.3
Ramp2
receptor (calcitonin) activity modifying protein 2
chr2_-_131042682 0.765 ENSMUST00000028787.5
ENSMUST00000110239.1
ENSMUST00000110234.1
Gfra4


glial cell line derived neurotrophic factor family receptor alpha 4


chr10_+_99263224 0.749 ENSMUST00000020118.4
Dusp6
dual specificity phosphatase 6
chr7_+_16452779 0.741 ENSMUST00000019302.8
Tmem160
transmembrane protein 160
chr2_-_122611238 0.695 ENSMUST00000028624.8
Gatm
glycine amidinotransferase (L-arginine:glycine amidinotransferase)
chr3_-_87263518 0.672 ENSMUST00000090986.4
Fcrls
Fc receptor-like S, scavenger receptor
chr15_-_98677451 0.671 ENSMUST00000120997.1
ENSMUST00000109149.2
ENSMUST00000003451.4
Rnd1


Rho family GTPase 1


chr8_+_72319033 0.657 ENSMUST00000067912.7
Klf2
Kruppel-like factor 2 (lung)
chr13_+_4233730 0.635 ENSMUST00000081326.6
Akr1c19
aldo-keto reductase family 1, member C19
chr17_+_29268788 0.612 ENSMUST00000064709.5
ENSMUST00000120346.1
BC004004

cDNA sequence BC004004

chr11_-_120713725 0.602 ENSMUST00000106154.1
ENSMUST00000106155.3
ENSMUST00000055424.6
ENSMUST00000026137.7
Stra13



stimulated by retinoic acid 13



chr19_-_57197435 0.601 ENSMUST00000111550.1
Ablim1
actin-binding LIM protein 1
chr13_-_51701041 0.596 ENSMUST00000110042.1
Gm15440
predicted gene 15440
chr4_-_14621669 0.596 ENSMUST00000143105.1
Slc26a7
solute carrier family 26, member 7
chr15_+_82252397 0.593 ENSMUST00000136948.1
1500009C09Rik
RIKEN cDNA 1500009C09 gene
chr13_+_63282142 0.577 ENSMUST00000159152.1
2010111I01Rik
RIKEN cDNA 2010111I01 gene
chr4_+_48049080 0.572 ENSMUST00000153369.1
Nr4a3
nuclear receptor subfamily 4, group A, member 3
chr2_-_64975762 0.551 ENSMUST00000156765.1
Grb14
growth factor receptor bound protein 14
chr18_-_31447383 0.540 ENSMUST00000025110.3
Syt4
synaptotagmin IV
chr4_+_124657646 0.529 ENSMUST00000053491.7
Pou3f1
POU domain, class 3, transcription factor 1
chr18_-_35722330 0.526 ENSMUST00000133064.1
Ecscr
endothelial cell surface expressed chemotaxis and apoptosis regulator
chr18_+_37484955 0.524 ENSMUST00000053856.4
Pcdhb17
protocadherin beta 17
chr11_-_26210553 0.522 ENSMUST00000101447.3
5730522E02Rik
RIKEN cDNA 5730522E02 gene
chr13_+_65512678 0.520 ENSMUST00000081471.2
Gm10139
predicted gene 10139
chr1_-_140183404 0.519 ENSMUST00000066859.6
ENSMUST00000111976.2
Cfh

complement component factor h

chr10_+_14523062 0.491 ENSMUST00000096020.5
Gm10335
predicted gene 10335
chr6_-_83831736 0.481 ENSMUST00000058383.8
Paip2b
poly(A) binding protein interacting protein 2B
chr3_+_106113229 0.479 ENSMUST00000079132.5
ENSMUST00000139086.1
Chia

chitinase, acidic

chr3_-_113574758 0.475 ENSMUST00000106540.1
Amy1
amylase 1, salivary
chr15_+_16778101 0.470 ENSMUST00000026432.6
Cdh9
cadherin 9
chr13_+_12702362 0.463 ENSMUST00000104944.2
Gm2399
predicted gene 2399
chr3_+_98013503 0.460 ENSMUST00000079812.6
Notch2
notch 2
chr4_-_118489755 0.457 ENSMUST00000184261.1
Tie1
tyrosine kinase with immunoglobulin-like and EGF-like domains 1
chr7_-_42706369 0.453 ENSMUST00000180131.1
Gm17067
predicted gene 17067
chr17_-_35895920 0.448 ENSMUST00000059740.8
2310061I04Rik
RIKEN cDNA 2310061I04 gene
chr18_+_32938955 0.446 ENSMUST00000042868.4
Camk4
calcium/calmodulin-dependent protein kinase IV
chr16_-_4880284 0.445 ENSMUST00000037843.6
Ubald1
UBA-like domain containing 1
chr6_+_48537560 0.434 ENSMUST00000040361.5
Atp6v0e2
ATPase, H+ transporting, lysosomal V0 subunit E2
chr5_-_120711927 0.430 ENSMUST00000031607.6
Dtx1
deltex 1 homolog (Drosophila)
chr11_-_110168073 0.428 ENSMUST00000044850.3
Abca9
ATP-binding cassette, sub-family A (ABC1), member 9
chr1_+_32172711 0.422 ENSMUST00000027226.5
Khdrbs2
KH domain containing, RNA binding, signal transduction associated 2
chr12_+_84361636 0.416 ENSMUST00000110276.1
Coq6
coenzyme Q6 homolog (yeast)
chr12_-_84698769 0.407 ENSMUST00000095550.2
Syndig1l
synapse differentiation inducing 1 like
chr8_+_119666498 0.406 ENSMUST00000024107.5
Wfdc1
WAP four-disulfide core domain 1
chr11_-_20332654 0.392 ENSMUST00000004634.6
Slc1a4
solute carrier family 1 (glutamate/neutral amino acid transporter), member 4
chr14_+_47373813 0.392 ENSMUST00000142734.1
ENSMUST00000150290.1
ENSMUST00000144794.1
ENSMUST00000146468.1
Lgals3



lectin, galactose binding, soluble 3



chr14_+_11227511 0.389 ENSMUST00000080237.3
Rpl21-ps4
ribosomal protein L21, pseudogene 4
chr1_-_184883218 0.386 ENSMUST00000048308.5
C130074G19Rik
RIKEN cDNA C130074G19 gene
chr11_-_120731944 0.385 ENSMUST00000154565.1
ENSMUST00000026148.2
Cbr2

carbonyl reductase 2

chr4_+_155803521 0.381 ENSMUST00000030942.6
ENSMUST00000185148.1
ENSMUST00000130188.1
Mrpl20


mitochondrial ribosomal protein L20


chr18_-_35215008 0.381 ENSMUST00000091636.3
Lrrtm2
leucine rich repeat transmembrane neuronal 2
chr5_+_8660059 0.379 ENSMUST00000047753.4
Abcb1a
ATP-binding cassette, sub-family B (MDR/TAP), member 1A
chr14_+_27238018 0.377 ENSMUST00000049206.5
Arhgef3
Rho guanine nucleotide exchange factor (GEF) 3
chr17_-_56140333 0.374 ENSMUST00000001256.4
Sema6b
sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6B
chr1_-_180245927 0.374 ENSMUST00000010753.7
Psen2
presenilin 2
chr10_-_63927434 0.373 ENSMUST00000079279.3
Gm10118
predicted gene 10118
chr6_+_55836878 0.362 ENSMUST00000044729.6
Ccdc129
coiled-coil domain containing 129
chr11_-_20332689 0.359 ENSMUST00000109594.1
Slc1a4
solute carrier family 1 (glutamate/neutral amino acid transporter), member 4
chrX_+_99042581 0.357 ENSMUST00000036606.7
Stard8
START domain containing 8
chr14_-_30353468 0.356 ENSMUST00000112249.1
Cacna1d
calcium channel, voltage-dependent, L type, alpha 1D subunit
chr8_-_70234097 0.351 ENSMUST00000130319.1
Armc6
armadillo repeat containing 6
chr15_-_79285502 0.350 ENSMUST00000165408.1
Baiap2l2
BAI1-associated protein 2-like 2
chr9_-_61914538 0.350 ENSMUST00000008036.7
Rplp1
ribosomal protein, large, P1
chr10_+_57784914 0.349 ENSMUST00000165013.1
Fabp7
fatty acid binding protein 7, brain
chr10_+_80167778 0.348 ENSMUST00000105365.2
ENSMUST00000054666.6
Cirbp

cold inducible RNA binding protein

chr3_+_129878571 0.348 ENSMUST00000029629.8
Pla2g12a
phospholipase A2, group XIIA
chr10_+_81633694 0.346 ENSMUST00000140345.1
ENSMUST00000126323.1
Ankrd24

ankyrin repeat domain 24

chr8_+_106603351 0.345 ENSMUST00000000312.5
ENSMUST00000167688.1
Cdh1

cadherin 1

chr12_-_85151264 0.343 ENSMUST00000019379.7
Rps6kl1
ribosomal protein S6 kinase-like 1
chr13_+_76579670 0.342 ENSMUST00000126960.1
ENSMUST00000109583.2
Mctp1

multiple C2 domains, transmembrane 1

chr19_-_32466575 0.340 ENSMUST00000078034.3
Rpl9-ps6
ribosomal protein L9, pseudogene 6
chr8_-_117673682 0.338 ENSMUST00000173522.1
ENSMUST00000174450.1
Sdr42e1

short chain dehydrogenase/reductase family 42E, member 1

chr8_+_84689308 0.333 ENSMUST00000125370.3
ENSMUST00000175784.1
Trmt1

tRNA methyltransferase 1

chr1_-_140183283 0.333 ENSMUST00000111977.1
Cfh
complement component factor h
chr16_-_97170707 0.326 ENSMUST00000056102.7
Dscam
Down syndrome cell adhesion molecule
chr10_-_86732409 0.323 ENSMUST00000070435.4
Fabp3-ps1
fatty acid binding protein 3, muscle and heart, pseudogene 1
chr4_-_62519885 0.320 ENSMUST00000107444.1
ENSMUST00000030090.3
Alad

aminolevulinate, delta-, dehydratase

chr10_-_81037300 0.319 ENSMUST00000059551.4
ENSMUST00000117276.2
Slc39a3

solute carrier family 39 (zinc transporter), member 3

chr6_+_8259288 0.317 ENSMUST00000159335.1
Gm16039
predicted gene 16039
chr16_-_17144415 0.316 ENSMUST00000115709.1
Ccdc116
coiled-coil domain containing 116
chr3_+_65109343 0.316 ENSMUST00000159525.1
ENSMUST00000049230.8
Kcnab1

potassium voltage-gated channel, shaker-related subfamily, beta member 1

chr11_+_35121126 0.314 ENSMUST00000069837.3
Slit3
slit homolog 3 (Drosophila)
chr17_-_24886304 0.311 ENSMUST00000044252.5
Nubp2
nucleotide binding protein 2
chr7_-_139582790 0.310 ENSMUST00000106095.2
Nkx6-2
NK6 homeobox 2
chr18_+_36365774 0.310 ENSMUST00000144158.1
Cystm1
cysteine-rich transmembrane module containing 1
chr15_-_43869993 0.303 ENSMUST00000067469.4
Tmem74
transmembrane protein 74
chrX_+_73064787 0.303 ENSMUST00000060418.6
Pnma3
paraneoplastic antigen MA3
chr13_-_92131494 0.303 ENSMUST00000099326.3
ENSMUST00000146492.1
Rasgrf2

RAS protein-specific guanine nucleotide-releasing factor 2

chr2_-_25224653 0.303 ENSMUST00000043584.4
Tubb4b
tubulin, beta 4B class IVB
chr8_+_110721462 0.301 ENSMUST00000052457.8
Mtss1l
metastasis suppressor 1-like
chr13_-_43304153 0.297 ENSMUST00000055341.5
Gfod1
glucose-fructose oxidoreductase domain containing 1
chr13_-_23622502 0.294 ENSMUST00000062045.2
Hist1h1e
histone cluster 1, H1e
chr11_+_26387194 0.293 ENSMUST00000109509.1
ENSMUST00000136830.1
Fancl

Fanconi anemia, complementation group L

chr1_-_180245757 0.293 ENSMUST00000111104.1
Psen2
presenilin 2
chr1_+_58210397 0.291 ENSMUST00000040442.5
Aox4
aldehyde oxidase 4
chr8_+_39005880 0.288 ENSMUST00000169034.1
Tusc3
tumor suppressor candidate 3
chr6_+_145934113 0.288 ENSMUST00000032383.7
Sspn
sarcospan
chr10_+_57784859 0.287 ENSMUST00000020024.5
Fabp7
fatty acid binding protein 7, brain
chr11_-_120549695 0.286 ENSMUST00000034913.4
Fam195b
family with sequence similarity 195, member B
chr8_+_25849618 0.286 ENSMUST00000098858.3
Kcnu1
potassium channel, subfamily U, member 1
chr12_-_115790884 0.282 ENSMUST00000081809.5
Ighv1-73
immunoglobulin heavy variable 1-73
chr14_-_55635602 0.281 ENSMUST00000047131.9
Ipo4
importin 4
chr1_+_45981548 0.280 ENSMUST00000085632.2
Rpl23a-ps1
ribosomal protein 23A, pseudogene 1
chr18_+_78349754 0.280 ENSMUST00000164064.1
Gm6133
predicted gene 6133
chr17_-_56874421 0.278 ENSMUST00000043062.4
Acsbg2
acyl-CoA synthetase bubblegum family member 2
chr13_-_76018524 0.277 ENSMUST00000050997.1
ENSMUST00000179078.1
ENSMUST00000167271.1
Rfesd


Rieske (Fe-S) domain containing


chr8_+_94810446 0.277 ENSMUST00000034232.1
Ccl17
chemokine (C-C motif) ligand 17
chr2_-_72986716 0.277 ENSMUST00000112062.1
Gm11084
predicted gene 11084
chr3_-_59210881 0.274 ENSMUST00000040622.1
P2ry13
purinergic receptor P2Y, G-protein coupled 13
chrX_+_159840463 0.272 ENSMUST00000112451.1
ENSMUST00000112453.2
Sh3kbp1

SH3-domain kinase binding protein 1

chr5_-_70842617 0.271 ENSMUST00000031119.1
Gabrg1
gamma-aminobutyric acid (GABA) A receptor, subunit gamma 1
chr5_+_90367204 0.268 ENSMUST00000068250.3
Gm9958
predicted gene 9958
chrX_+_134585644 0.268 ENSMUST00000113211.1
Rpl36a
ribosomal protein L36A
chr2_+_164460945 0.268 ENSMUST00000072452.4
Sys1
SYS1 Golgi-localized integral membrane protein homolog (S. cerevisiae)
chr8_-_86580664 0.261 ENSMUST00000131423.1
ENSMUST00000152438.1
Abcc12

ATP-binding cassette, sub-family C (CFTR/MRP), member 12

chr4_-_58499398 0.260 ENSMUST00000107570.1
Lpar1
lysophosphatidic acid receptor 1
chr11_-_110251736 0.259 ENSMUST00000044003.7
Abca6
ATP-binding cassette, sub-family A (ABC1), member 6
chr8_-_69890967 0.258 ENSMUST00000152938.1
Yjefn3
YjeF N-terminal domain containing 3
chr14_-_68655804 0.257 ENSMUST00000111072.1
ENSMUST00000022642.5
Adam28

a disintegrin and metallopeptidase domain 28

chr17_+_17402672 0.257 ENSMUST00000115576.2
Lix1
limb expression 1 homolog (chicken)
chr15_+_18818895 0.253 ENSMUST00000166873.2
Cdh10
cadherin 10
chr18_-_12819842 0.252 ENSMUST00000119043.1
Osbpl1a
oxysterol binding protein-like 1A
chr10_-_62327757 0.252 ENSMUST00000139228.1
Hk1
hexokinase 1
chr3_-_96058446 0.252 ENSMUST00000015891.5
Vps45
vacuolar protein sorting 45 (yeast)
chr15_-_80083374 0.251 ENSMUST00000081650.7
Rpl3
ribosomal protein L3
chr2_-_151744142 0.249 ENSMUST00000109869.1
Psmf1
proteasome (prosome, macropain) inhibitor subunit 1
chr10_+_82378593 0.248 ENSMUST00000165906.1
Gm4924
predicted gene 4924
chr16_+_3908801 0.248 ENSMUST00000145150.2
ENSMUST00000040881.7
Cluap1

clusterin associated protein 1

chr15_+_78935177 0.248 ENSMUST00000145157.1
ENSMUST00000123013.1
Nol12

nucleolar protein 12

chr3_+_89266552 0.247 ENSMUST00000040824.1
Dpm3
dolichyl-phosphate mannosyltransferase polypeptide 3
chr10_-_110000219 0.247 ENSMUST00000032719.7
Nav3
neuron navigator 3
chr8_+_46490968 0.247 ENSMUST00000110372.1
ENSMUST00000130563.1
Acsl1

acyl-CoA synthetase long-chain family member 1

chr1_+_23761749 0.246 ENSMUST00000144602.1
B3gat2
beta-1,3-glucuronyltransferase 2 (glucuronosyltransferase S)
chr17_+_20945311 0.246 ENSMUST00000007708.7
Ppp2r1a
protein phosphatase 2 (formerly 2A), regulatory subunit A (PR 65), alpha isoform
chr4_+_59035088 0.245 ENSMUST00000041160.6
Gng10
guanine nucleotide binding protein (G protein), gamma 10
chr1_-_75142360 0.242 ENSMUST00000041213.5
Cnppd1
cyclin Pas1/PHO80 domain containing 1
chr19_-_11604828 0.239 ENSMUST00000025582.4
Ms4a6d
membrane-spanning 4-domains, subfamily A, member 6D
chr17_-_35897371 0.238 ENSMUST00000148721.1
2310061I04Rik
RIKEN cDNA 2310061I04 gene
chr10_+_81628570 0.237 ENSMUST00000153573.1
ENSMUST00000119336.1
Ankrd24

ankyrin repeat domain 24

chr10_-_39122277 0.236 ENSMUST00000136546.1
Fam229b
family with sequence similarity 229, member B
chr3_+_130068390 0.235 ENSMUST00000076703.6
Gm9396
predicted gene 9396
chr15_+_97247011 0.234 ENSMUST00000059433.6
Pced1b
PC-esterase domain containing 1B
chr2_+_172370658 0.230 ENSMUST00000151511.1
ENSMUST00000116375.1
Cstf1

cleavage stimulation factor, 3' pre-RNA, subunit 1

chr6_+_113333304 0.230 ENSMUST00000147945.1
Ogg1
8-oxoguanine DNA-glycosylase 1
chr10_+_88201117 0.229 ENSMUST00000182183.1
Ccdc53
coiled-coil domain containing 53
chr10_-_39133848 0.226 ENSMUST00000134279.1
ENSMUST00000139743.1
ENSMUST00000149949.1
ENSMUST00000124941.1
ENSMUST00000125042.1
ENSMUST00000063204.2
Fam229b





family with sequence similarity 229, member B





chr6_-_124741374 0.225 ENSMUST00000004389.5
Grcc10
gene rich cluster, C10 gene
chr3_-_86142684 0.225 ENSMUST00000029722.6
Rps3a1
ribosomal protein S3A1
chr7_-_19715395 0.222 ENSMUST00000032555.9
ENSMUST00000093552.5
Tomm40

translocase of outer mitochondrial membrane 40 homolog (yeast)

chr16_+_91391721 0.220 ENSMUST00000160764.1
Gm21970
predicted gene 21970
chr3_+_138277489 0.219 ENSMUST00000004232.9
Adh1
alcohol dehydrogenase 1 (class I)
chr8_-_54718664 0.218 ENSMUST00000144711.2
ENSMUST00000093510.2
Wdr17

WD repeat domain 17

chr19_-_7217549 0.218 ENSMUST00000039758.4
Cox8a
cytochrome c oxidase subunit VIIIa
chr14_-_54517353 0.217 ENSMUST00000023873.5
Prmt5
protein arginine N-methyltransferase 5
chr18_-_61259987 0.214 ENSMUST00000170335.2
Rps2-ps10
ribosomal protein S2, pseudogene 10
chr12_-_119238794 0.213 ENSMUST00000026360.8
Itgb8
integrin beta 8
chr19_+_38481057 0.213 ENSMUST00000182481.1
Plce1
phospholipase C, epsilon 1
chr10_+_86022189 0.212 ENSMUST00000120344.1
ENSMUST00000117597.1
Fbxo7

F-box protein 7

chr4_-_155086271 0.211 ENSMUST00000030914.3
Rer1
RER1 retention in endoplasmic reticulum 1 homolog (S. cerevisiae)
chr1_-_184033998 0.211 ENSMUST00000050306.5
1700056E22Rik
RIKEN cDNA 1700056E22 gene
chrX_-_150814265 0.211 ENSMUST00000026302.6
ENSMUST00000129768.1
ENSMUST00000112699.2
Maged2


melanoma antigen, family D, 2


chrX_+_155262443 0.210 ENSMUST00000026324.9
Acot9
acyl-CoA thioesterase 9
chr8_+_70527724 0.208 ENSMUST00000119353.2
ENSMUST00000075491.7
Fkbp8

FK506 binding protein 8

chr5_+_115559505 0.208 ENSMUST00000156359.1
ENSMUST00000152976.1
Rplp0

ribosomal protein, large, P0

chr5_+_115559467 0.207 ENSMUST00000086519.5
Rplp0
ribosomal protein, large, P0
chr11_-_84916338 0.207 ENSMUST00000103195.4
Znhit3
zinc finger, HIT type 3
chr3_-_130709419 0.206 ENSMUST00000043937.7
Ostc
oligosaccharyltransferase complex subunit
chr17_+_33629078 0.205 ENSMUST00000166627.1
ENSMUST00000073570.5
ENSMUST00000170225.1
Zfp414


zinc finger protein 414


chrX_-_139714481 0.202 ENSMUST00000183728.1
Gm15013
predicted gene 15013
chr6_+_89643982 0.202 ENSMUST00000000828.6
ENSMUST00000101171.1
Txnrd3

thioredoxin reductase 3

chr8_+_83666827 0.202 ENSMUST00000019608.5
Ptger1
prostaglandin E receptor 1 (subtype EP1)
chr11_+_4186789 0.202 ENSMUST00000041042.6
ENSMUST00000180088.1
Tbc1d10a

TBC1 domain family, member 10a

chrX_+_7884244 0.201 ENSMUST00000115663.3
Slc35a2
solute carrier family 35 (UDP-galactose transporter), member A2
chr17_-_56716788 0.200 ENSMUST00000067931.5
Vmac
vimentin-type intermediate filament associated coiled-coil protein
chr5_-_139775631 0.199 ENSMUST00000072607.4
Ints1
integrator complex subunit 1
chr7_-_132576372 0.199 ENSMUST00000084500.6
Oat
ornithine aminotransferase
chr11_+_120713919 0.198 ENSMUST00000026139.7
ENSMUST00000151852.1
Lrrc45

leucine rich repeat containing 45

chr2_+_39008076 0.197 ENSMUST00000112862.1
ENSMUST00000090993.5
Arpc5l

actin related protein 2/3 complex, subunit 5-like

chr14_+_55561060 0.197 ENSMUST00000117701.1
Dcaf11
DDB1 and CUL4 associated factor 11
chr8_+_71469186 0.196 ENSMUST00000124745.1
ENSMUST00000138892.1
ENSMUST00000147642.1
Dda1


DET1 and DDB1 associated 1


chr8_+_84689247 0.195 ENSMUST00000109767.2
ENSMUST00000177084.1
ENSMUST00000109768.2
ENSMUST00000152301.2
ENSMUST00000177423.1
Trmt1




tRNA methyltransferase 1





Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 2.1 GO:0019532 oxalate transport(GO:0019532)
0.3 0.9 GO:1902256 apoptotic process involved in outflow tract morphogenesis(GO:0003275) regulation of apoptotic process involved in outflow tract morphogenesis(GO:1902256) response to chemokine(GO:1990868) cellular response to chemokine(GO:1990869)
0.3 1.1 GO:2000832 androgen secretion(GO:0035935) testosterone secretion(GO:0035936) positive regulation of apoptotic DNA fragmentation(GO:1902512) negative regulation of steroid hormone secretion(GO:2000832) regulation of androgen secretion(GO:2000834) regulation of testosterone secretion(GO:2000843)
0.3 0.8 GO:1903538 meiotic cell cycle process involved in oocyte maturation(GO:1903537) regulation of meiotic cell cycle process involved in oocyte maturation(GO:1903538)
0.2 0.7 GO:0042663 regulation of endodermal cell fate specification(GO:0042663)
0.2 0.7 GO:0006601 creatine biosynthetic process(GO:0006601)
0.2 1.1 GO:0045347 negative regulation of MHC class II biosynthetic process(GO:0045347) negative regulation of cytolysis(GO:0045918)
0.2 0.6 GO:0038095 positive regulation of mast cell cytokine production(GO:0032765) Fc-epsilon receptor signaling pathway(GO:0038095)
0.2 0.5 GO:0002940 tRNA N2-guanine methylation(GO:0002940)
0.2 0.7 GO:0015825 L-serine transport(GO:0015825)
0.2 0.5 GO:0035622 intrahepatic bile duct development(GO:0035622) cholangiocyte proliferation(GO:1990705)
0.1 0.9 GO:0045919 positive regulation of cytolysis(GO:0045919)
0.1 0.4 GO:0071677 positive regulation of mononuclear cell migration(GO:0071677)
0.1 0.4 GO:0006116 NADH oxidation(GO:0006116)
0.1 0.8 GO:0097646 calcitonin family receptor signaling pathway(GO:0097646) amylin receptor signaling pathway(GO:0097647)
0.1 0.3 GO:0060060 post-embryonic retina morphogenesis in camera-type eye(GO:0060060)
0.1 0.1 GO:2000670 positive regulation of dendritic cell apoptotic process(GO:2000670)
0.1 0.6 GO:0071499 response to laminar fluid shear stress(GO:0034616) cellular response to laminar fluid shear stress(GO:0071499)
0.1 1.1 GO:0030432 peristalsis(GO:0030432)
0.1 0.4 GO:0046618 drug export(GO:0046618)
0.1 0.3 GO:0046110 xanthine metabolic process(GO:0046110)
0.1 0.4 GO:0086046 membrane depolarization during SA node cell action potential(GO:0086046)
0.1 0.2 GO:0002314 germinal center B cell differentiation(GO:0002314)
0.1 0.4 GO:1903207 neuron death in response to hydrogen peroxide(GO:0036476) regulation of hydrogen peroxide-induced neuron death(GO:1903207) negative regulation of hydrogen peroxide-induced neuron death(GO:1903208)
0.1 0.6 GO:1901727 positive regulation of histone deacetylase activity(GO:1901727)
0.1 0.2 GO:0061744 motor behavior(GO:0061744)
0.1 0.1 GO:0032829 regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation(GO:0032829)
0.1 0.2 GO:0034310 primary alcohol catabolic process(GO:0034310)
0.1 0.3 GO:0070417 cellular response to cold(GO:0070417)
0.1 0.3 GO:0060066 oviduct development(GO:0060066)
0.1 0.5 GO:2000301 negative regulation of synaptic vesicle exocytosis(GO:2000301)
0.1 0.3 GO:1904565 response to 1-oleoyl-sn-glycerol 3-phosphate(GO:1904565) cellular response to 1-oleoyl-sn-glycerol 3-phosphate(GO:1904566)
0.1 1.0 GO:0042541 hemoglobin biosynthetic process(GO:0042541)
0.1 0.2 GO:0015786 UDP-glucose transport(GO:0015786)
0.1 0.2 GO:0007521 muscle cell fate determination(GO:0007521) mammary placode formation(GO:0060596)
0.1 0.2 GO:1905051 regulation of base-excision repair(GO:1905051) positive regulation of base-excision repair(GO:1905053)
0.1 3.9 GO:0038083 peptidyl-tyrosine autophosphorylation(GO:0038083)
0.1 0.2 GO:0045575 basophil activation involved in immune response(GO:0002276) basophil activation(GO:0045575)
0.1 0.2 GO:0043985 histone H4-R3 methylation(GO:0043985)
0.1 0.2 GO:0009826 unidimensional cell growth(GO:0009826)
0.1 0.1 GO:2000277 positive regulation of oxidative phosphorylation uncoupler activity(GO:2000277)
0.0 0.6 GO:0043589 skin morphogenesis(GO:0043589)
0.0 0.2 GO:0021508 floor plate formation(GO:0021508) floor plate morphogenesis(GO:0033505)
0.0 0.7 GO:0016322 neuron remodeling(GO:0016322)
0.0 0.2 GO:0002901 mature B cell apoptotic process(GO:0002901) regulation of mature B cell apoptotic process(GO:0002905) negative regulation of mature B cell apoptotic process(GO:0002906)
0.0 0.2 GO:0072531 pyrimidine-containing compound transmembrane transport(GO:0072531)
0.0 0.2 GO:0006481 C-terminal protein methylation(GO:0006481)
0.0 0.2 GO:0060158 phospholipase C-activating dopamine receptor signaling pathway(GO:0060158)
0.0 0.3 GO:0021913 regulation of transcription from RNA polymerase II promoter involved in spinal cord motor neuron fate specification(GO:0021912) regulation of transcription from RNA polymerase II promoter involved in ventral spinal cord interneuron specification(GO:0021913)
0.0 0.8 GO:0001553 luteinization(GO:0001553)
0.0 0.2 GO:0032570 response to progesterone(GO:0032570)
0.0 0.3 GO:0016584 nucleosome positioning(GO:0016584)
0.0 0.1 GO:0010958 regulation of amino acid import(GO:0010958) regulation of DNA-templated transcription, termination(GO:0031554)
0.0 0.9 GO:0006958 complement activation, classical pathway(GO:0006958)
0.0 0.3 GO:0071941 nitrate metabolic process(GO:0042126) nitrogen cycle metabolic process(GO:0071941)
0.0 0.6 GO:0060134 prepulse inhibition(GO:0060134)
0.0 0.1 GO:1901421 generation of catalytic spliceosome for second transesterification step(GO:0000350) positive regulation of response to alcohol(GO:1901421)
0.0 0.7 GO:0006744 ubiquinone biosynthetic process(GO:0006744)
0.0 0.1 GO:0071726 response to diacyl bacterial lipopeptide(GO:0071724) cellular response to diacyl bacterial lipopeptide(GO:0071726)
0.0 0.1 GO:2000418 positive regulation of eosinophil migration(GO:2000418)
0.0 0.4 GO:0010359 regulation of anion channel activity(GO:0010359)
0.0 0.4 GO:0000042 protein targeting to Golgi(GO:0000042)
0.0 0.2 GO:0009235 cobalamin metabolic process(GO:0009235)
0.0 0.2 GO:0070294 renal sodium ion transport(GO:0003096) renal sodium ion absorption(GO:0070294)
0.0 0.2 GO:0019695 choline metabolic process(GO:0019695)
0.0 0.1 GO:0006659 phosphatidylserine biosynthetic process(GO:0006659)
0.0 0.1 GO:0051591 response to cAMP(GO:0051591)
0.0 0.1 GO:0097118 neuroligin clustering involved in postsynaptic membrane assembly(GO:0097118)
0.0 0.2 GO:0045039 protein import into mitochondrial inner membrane(GO:0045039)
0.0 0.2 GO:0051012 microtubule sliding(GO:0051012)
0.0 0.2 GO:0045002 double-strand break repair via single-strand annealing(GO:0045002)
0.0 0.2 GO:0006363 termination of RNA polymerase I transcription(GO:0006363)
0.0 0.1 GO:0072488 ammonium transmembrane transport(GO:0072488)
0.0 0.4 GO:1990173 protein localization to nuclear body(GO:1903405) protein localization to Cajal body(GO:1904867) regulation of protein localization to Cajal body(GO:1904869) positive regulation of protein localization to Cajal body(GO:1904871) protein localization to nucleoplasm(GO:1990173)
0.0 0.3 GO:0006968 cellular defense response(GO:0006968)
0.0 2.8 GO:0007601 visual perception(GO:0007601)
0.0 0.5 GO:0045947 negative regulation of translational initiation(GO:0045947)
0.0 1.0 GO:0071353 cellular response to interleukin-4(GO:0071353)
0.0 0.5 GO:2000353 positive regulation of endothelial cell apoptotic process(GO:2000353)
0.0 0.2 GO:1900028 negative regulation of ruffle assembly(GO:1900028)
0.0 0.1 GO:0035063 nuclear speck organization(GO:0035063)
0.0 0.2 GO:0034214 protein hexamerization(GO:0034214)
0.0 0.6 GO:0016226 iron-sulfur cluster assembly(GO:0016226) metallo-sulfur cluster assembly(GO:0031163)
0.0 0.2 GO:0032534 regulation of microvillus assembly(GO:0032534)
0.0 0.2 GO:0035269 protein O-linked mannosylation(GO:0035269)
0.0 0.2 GO:0044539 long-chain fatty acid import(GO:0044539)
0.0 0.3 GO:0006610 ribosomal protein import into nucleus(GO:0006610)
0.0 0.5 GO:0030032 lamellipodium assembly(GO:0030032)
0.0 0.2 GO:0006102 isocitrate metabolic process(GO:0006102)
0.0 0.2 GO:0007000 nucleolus organization(GO:0007000)
0.0 0.1 GO:0034124 regulation of MyD88-dependent toll-like receptor signaling pathway(GO:0034124)
0.0 0.3 GO:1903963 arachidonic acid secretion(GO:0050482) arachidonate transport(GO:1903963)
0.0 0.1 GO:0002925 positive regulation of humoral immune response mediated by circulating immunoglobulin(GO:0002925)
0.0 0.1 GO:0002014 vasoconstriction of artery involved in ischemic response to lowering of systemic arterial blood pressure(GO:0002014)
0.0 0.2 GO:0071340 skeletal muscle acetylcholine-gated channel clustering(GO:0071340)
0.0 0.1 GO:0071033 nuclear retention of pre-mRNA at the site of transcription(GO:0071033) CUT catabolic process(GO:0071034) CUT metabolic process(GO:0071043)
0.0 0.0 GO:0006957 complement activation, alternative pathway(GO:0006957)
0.0 0.4 GO:2000251 positive regulation of actin cytoskeleton reorganization(GO:2000251)
0.0 0.2 GO:0006123 mitochondrial electron transport, cytochrome c to oxygen(GO:0006123)
0.0 0.3 GO:0001573 ganglioside metabolic process(GO:0001573)
0.0 0.2 GO:0042572 retinol metabolic process(GO:0042572)
0.0 0.1 GO:0045903 positive regulation of translational fidelity(GO:0045903)
0.0 0.3 GO:1902260 negative regulation of delayed rectifier potassium channel activity(GO:1902260) negative regulation of voltage-gated potassium channel activity(GO:1903817)
0.0 0.1 GO:0032788 saturated monocarboxylic acid metabolic process(GO:0032788) unsaturated monocarboxylic acid metabolic process(GO:0032789)
0.0 0.6 GO:0043171 peptide catabolic process(GO:0043171)
0.0 0.1 GO:1903070 negative regulation of ER-associated ubiquitin-dependent protein catabolic process(GO:1903070)
0.0 0.2 GO:0050860 negative regulation of T cell receptor signaling pathway(GO:0050860)
0.0 0.3 GO:0007194 negative regulation of adenylate cyclase activity(GO:0007194)
0.0 0.4 GO:0045581 negative regulation of T cell differentiation(GO:0045581)
0.0 0.1 GO:1901386 negative regulation of voltage-gated calcium channel activity(GO:1901386)
0.0 0.2 GO:0071578 zinc II ion transmembrane import(GO:0071578)
0.0 0.2 GO:0033008 positive regulation of mast cell activation involved in immune response(GO:0033008) positive regulation of mast cell degranulation(GO:0043306)
0.0 0.2 GO:0034472 snRNA 3'-end processing(GO:0034472)
0.0 0.1 GO:0016075 rRNA catabolic process(GO:0016075)
0.0 0.0 GO:0051643 endoplasmic reticulum localization(GO:0051643)
0.0 0.4 GO:0002091 negative regulation of receptor internalization(GO:0002091)
0.0 0.1 GO:0099590 neurotransmitter receptor internalization(GO:0099590)
0.0 0.1 GO:1903215 negative regulation of protein targeting to mitochondrion(GO:1903215)
0.0 0.4 GO:0046827 positive regulation of protein export from nucleus(GO:0046827)
0.0 0.1 GO:0048875 chemical homeostasis within a tissue(GO:0048875)
0.0 0.5 GO:0045026 plasma membrane fusion(GO:0045026)
0.0 0.0 GO:0032661 regulation of interleukin-18 production(GO:0032661) negative regulation of interleukin-18 production(GO:0032701)
0.0 0.2 GO:0030150 protein import into mitochondrial matrix(GO:0030150)
0.0 0.2 GO:0045741 positive regulation of epidermal growth factor-activated receptor activity(GO:0045741)
0.0 0.3 GO:0006829 zinc II ion transport(GO:0006829)
0.0 0.0 GO:0046381 CMP-N-acetylneuraminate metabolic process(GO:0046381)
0.0 0.1 GO:0010807 regulation of synaptic vesicle priming(GO:0010807)
0.0 0.2 GO:0090110 cargo loading into COPII-coated vesicle(GO:0090110)
0.0 0.1 GO:0098655 cation transmembrane transport(GO:0098655)
0.0 0.1 GO:0030539 male genitalia development(GO:0030539)
0.0 0.2 GO:2000310 regulation of N-methyl-D-aspartate selective glutamate receptor activity(GO:2000310)
0.0 0.1 GO:0072643 interferon-gamma secretion(GO:0072643)
0.0 0.1 GO:0048147 negative regulation of fibroblast proliferation(GO:0048147)
0.0 0.3 GO:0097178 ruffle assembly(GO:0097178)
0.0 0.2 GO:0050650 chondroitin sulfate proteoglycan biosynthetic process(GO:0050650)
0.0 0.3 GO:0007214 gamma-aminobutyric acid signaling pathway(GO:0007214)
0.0 0.0 GO:0045075 interleukin-12 biosynthetic process(GO:0042090) regulation of interleukin-12 biosynthetic process(GO:0045075)
0.0 0.1 GO:0046929 negative regulation of neurotransmitter secretion(GO:0046929)
0.0 0.2 GO:0016558 protein import into peroxisome matrix(GO:0016558)
0.0 0.1 GO:0070100 negative regulation of chemokine-mediated signaling pathway(GO:0070100)
0.0 0.9 GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)
0.0 0.3 GO:0015991 energy coupled proton transmembrane transport, against electrochemical gradient(GO:0015988) ATP hydrolysis coupled proton transport(GO:0015991)
0.0 0.1 GO:0000463 maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000463)
0.0 0.1 GO:0032074 negative regulation of nuclease activity(GO:0032074)
0.0 0.3 GO:0032292 myelination in peripheral nervous system(GO:0022011) peripheral nervous system axon ensheathment(GO:0032292)
0.0 0.2 GO:0032211 negative regulation of telomere maintenance via telomerase(GO:0032211)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.1 GO:0042567 insulin-like growth factor ternary complex(GO:0042567)
0.3 1.1 GO:0031838 haptoglobin-hemoglobin complex(GO:0031838)
0.2 0.8 GO:1903440 calcitonin family receptor complex(GO:1903439) amylin receptor complex(GO:1903440)
0.1 1.1 GO:0031091 platelet alpha granule(GO:0031091)
0.1 0.4 GO:1990037 Lewy body core(GO:1990037)
0.1 0.2 GO:0033185 dolichol-phosphate-mannose synthase complex(GO:0033185)
0.1 0.2 GO:0044194 cytolytic granule(GO:0044194)
0.0 0.2 GO:0045098 type III intermediate filament(GO:0045098)
0.0 0.4 GO:0046581 intercellular canaliculus(GO:0046581)
0.0 0.7 GO:0008250 oligosaccharyltransferase complex(GO:0008250)
0.0 0.4 GO:0071439 clathrin complex(GO:0071439)
0.0 0.1 GO:1903095 microprocessor complex(GO:0070877) ribonuclease III complex(GO:1903095)
0.0 0.9 GO:0097386 glial cell projection(GO:0097386)
0.0 0.4 GO:1990454 L-type voltage-gated calcium channel complex(GO:1990454)
0.0 0.2 GO:0042719 mitochondrial intermembrane space protein transporter complex(GO:0042719)
0.0 0.7 GO:0035253 ciliary rootlet(GO:0035253)
0.0 0.3 GO:0045298 tubulin complex(GO:0045298)
0.0 4.5 GO:0031234 extrinsic component of cytoplasmic side of plasma membrane(GO:0031234)
0.0 0.3 GO:0043219 flotillin complex(GO:0016600) lateral loop(GO:0043219)
0.0 0.2 GO:0005742 mitochondrial outer membrane translocase complex(GO:0005742)
0.0 0.3 GO:0033179 proton-transporting V-type ATPase, V0 domain(GO:0033179)
0.0 0.4 GO:0002199 zona pellucida receptor complex(GO:0002199)
0.0 0.2 GO:0042613 MHC class II protein complex(GO:0042613)
0.0 0.3 GO:0043240 Fanconi anaemia nuclear complex(GO:0043240)
0.0 0.1 GO:0046696 lipopolysaccharide receptor complex(GO:0046696)
0.0 0.2 GO:0097524 sperm plasma membrane(GO:0097524)
0.0 0.2 GO:0034709 methylosome(GO:0034709)
0.0 0.1 GO:0070044 synaptobrevin 2-SNAP-25-syntaxin-1a complex(GO:0070044)
0.0 0.5 GO:0005839 proteasome core complex(GO:0005839)
0.0 0.3 GO:0031083 BLOC-1 complex(GO:0031083)
0.0 0.3 GO:0005751 mitochondrial respiratory chain complex IV(GO:0005751)
0.0 0.2 GO:0042571 immunoglobulin complex, circulating(GO:0042571)
0.0 0.2 GO:0000783 telomere cap complex(GO:0000782) nuclear telomere cap complex(GO:0000783)
0.0 0.3 GO:0016010 dystrophin-associated glycoprotein complex(GO:0016010) glycoprotein complex(GO:0090665)
0.0 0.1 GO:1990415 Pex17p-Pex14p docking complex(GO:1990415) peroxisomal importomer complex(GO:1990429)
0.0 1.3 GO:0022625 cytosolic large ribosomal subunit(GO:0022625)
0.0 0.1 GO:0005853 eukaryotic translation elongation factor 1 complex(GO:0005853)
0.0 0.2 GO:0005885 Arp2/3 protein complex(GO:0005885)
0.0 0.7 GO:0030173 integral component of Golgi membrane(GO:0030173)
0.0 0.3 GO:0031616 spindle pole centrosome(GO:0031616)
0.0 0.1 GO:0036056 filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057)
0.0 0.4 GO:0000788 nuclear nucleosome(GO:0000788)
0.0 0.1 GO:1990726 Lsm1-7-Pat1 complex(GO:1990726)
0.0 0.3 GO:0097228 sperm principal piece(GO:0097228)
0.0 0.1 GO:0071014 post-mRNA release spliceosomal complex(GO:0071014)
0.0 0.2 GO:0030127 COPII vesicle coat(GO:0030127)
0.0 0.8 GO:0005758 mitochondrial intermembrane space(GO:0005758)
0.0 0.1 GO:0005952 cAMP-dependent protein kinase complex(GO:0005952)
0.0 0.1 GO:0032426 stereocilium tip(GO:0032426)
0.0 0.2 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.0 0.0 GO:0097543 ciliary inversin compartment(GO:0097543)
0.0 0.0 GO:1990730 VCP-NSFL1C complex(GO:1990730)
0.0 0.5 GO:0022627 cytosolic small ribosomal subunit(GO:0022627)
0.0 0.1 GO:0000276 mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 2.7 GO:0019841 retinol binding(GO:0019841)
0.3 1.0 GO:0016748 succinyltransferase activity(GO:0016748)
0.3 1.1 GO:0001602 pancreatic polypeptide receptor activity(GO:0001602)
0.3 1.1 GO:0031721 haptoglobin binding(GO:0031720) hemoglobin alpha binding(GO:0031721)
0.3 0.8 GO:0016167 glial cell-derived neurotrophic factor receptor activity(GO:0016167)
0.2 1.1 GO:0072542 protein phosphatase activator activity(GO:0072542)
0.2 0.9 GO:0001851 complement component C3b binding(GO:0001851)
0.2 1.0 GO:0048248 CXCR3 chemokine receptor binding(GO:0048248)
0.2 0.8 GO:0005459 UDP-galactose transmembrane transporter activity(GO:0005459)
0.2 2.1 GO:0019531 secondary active sulfate transmembrane transporter activity(GO:0008271) oxalate transmembrane transporter activity(GO:0019531)
0.2 0.5 GO:0016160 alpha-amylase activity(GO:0004556) amylase activity(GO:0016160)
0.2 0.8 GO:0097643 amylin receptor activity(GO:0097643)
0.1 0.5 GO:0030348 syntaxin-3 binding(GO:0030348)
0.1 5.1 GO:0005070 SH3/SH2 adaptor activity(GO:0005070)
0.1 0.4 GO:0008534 oxidized purine nucleobase lesion DNA N-glycosylase activity(GO:0008534)
0.1 0.5 GO:0019863 IgE binding(GO:0019863)
0.1 0.1 GO:0031697 beta-1 adrenergic receptor binding(GO:0031697)
0.1 0.5 GO:0004809 tRNA (guanine-N2-)-methyltransferase activity(GO:0004809)
0.1 0.4 GO:0004090 carbonyl reductase (NADPH) activity(GO:0004090)
0.1 0.3 GO:0060072 large conductance calcium-activated potassium channel activity(GO:0060072)
0.1 0.8 GO:0015180 L-alanine transmembrane transporter activity(GO:0015180) L-proline transmembrane transporter activity(GO:0015193) alanine transmembrane transporter activity(GO:0022858)
0.1 0.7 GO:0042500 aspartic endopeptidase activity, intramembrane cleaving(GO:0042500)
0.1 0.2 GO:0043758 acetate-CoA ligase (ADP-forming) activity(GO:0043758)
0.1 0.4 GO:0008559 xenobiotic-transporting ATPase activity(GO:0008559) phosphatidylcholine-translocating ATPase activity(GO:0090554)
0.1 0.2 GO:0098809 nitrite reductase activity(GO:0098809)
0.1 0.2 GO:0004022 alcohol dehydrogenase (NAD) activity(GO:0004022)
0.1 0.2 GO:0003986 acetyl-CoA hydrolase activity(GO:0003986)
0.1 0.3 GO:0030151 molybdenum ion binding(GO:0030151)
0.1 0.8 GO:0008301 DNA binding, bending(GO:0008301)
0.1 0.2 GO:0008192 RNA guanylyltransferase activity(GO:0008192)
0.1 0.2 GO:0017150 tRNA dihydrouridine synthase activity(GO:0017150)
0.1 0.2 GO:0004449 isocitrate dehydrogenase (NAD+) activity(GO:0004449)
0.1 0.2 GO:0004582 dolichyl-phosphate beta-D-mannosyltransferase activity(GO:0004582)
0.1 0.2 GO:0031826 type 2A serotonin receptor binding(GO:0031826)
0.1 0.2 GO:0047179 platelet-activating factor acetyltransferase activity(GO:0047179)
0.1 0.3 GO:0003854 3-beta-hydroxy-delta5-steroid dehydrogenase activity(GO:0003854)
0.1 0.2 GO:0004920 interleukin-10 receptor activity(GO:0004920)
0.1 0.2 GO:0035651 AP-3 adaptor complex binding(GO:0035651)
0.1 0.2 GO:0035243 protein-arginine omega-N symmetric methyltransferase activity(GO:0035243)
0.0 0.2 GO:0015018 galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase activity(GO:0015018)
0.0 0.2 GO:0019962 interferon receptor activity(GO:0004904) type I interferon receptor activity(GO:0004905) type I interferon binding(GO:0019962)
0.0 0.2 GO:0004104 choline kinase activity(GO:0004103) cholinesterase activity(GO:0004104) choline binding(GO:0033265)
0.0 0.2 GO:0003880 protein C-terminal carboxyl O-methyltransferase activity(GO:0003880)
0.0 0.4 GO:0086007 voltage-gated calcium channel activity involved in cardiac muscle cell action potential(GO:0086007)
0.0 0.2 GO:0000179 rRNA (adenine-N6,N6-)-dimethyltransferase activity(GO:0000179)
0.0 0.1 GO:0046899 nucleoside triphosphate adenylate kinase activity(GO:0046899)
0.0 0.2 GO:0004954 icosanoid receptor activity(GO:0004953) prostanoid receptor activity(GO:0004954) prostaglandin receptor activity(GO:0004955)
0.0 0.3 GO:0045028 G-protein coupled nucleotide receptor activity(GO:0001608) G-protein coupled purinergic nucleotide receptor activity(GO:0045028)
0.0 0.2 GO:0042289 MHC class II protein binding(GO:0042289)
0.0 0.1 GO:0071723 lipopeptide binding(GO:0071723)
0.0 0.9 GO:0016769 transferase activity, transferring nitrogenous groups(GO:0016769)
0.0 0.3 GO:0035727 lysophosphatidic acid binding(GO:0035727) lysophosphatidic acid receptor activity(GO:0070915)
0.0 0.5 GO:0004576 oligosaccharyl transferase activity(GO:0004576) dolichyl-diphosphooligosaccharide-protein glycotransferase activity(GO:0004579)
0.0 0.8 GO:0005104 fibroblast growth factor receptor binding(GO:0005104)
0.0 0.1 GO:0016230 sphingomyelin phosphodiesterase activator activity(GO:0016230)
0.0 0.3 GO:0070290 N-acylphosphatidylethanolamine-specific phospholipase D activity(GO:0070290)
0.0 0.3 GO:0070181 small ribosomal subunit rRNA binding(GO:0070181)
0.0 0.2 GO:0004791 thioredoxin-disulfide reductase activity(GO:0004791)
0.0 0.3 GO:0032564 dATP binding(GO:0032564)
0.0 0.5 GO:0004033 aldo-keto reductase (NADP) activity(GO:0004033)
0.0 0.2 GO:0015288 porin activity(GO:0015288)
0.0 0.7 GO:0071949 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen(GO:0016709) FAD binding(GO:0071949)
0.0 0.2 GO:1990430 extracellular matrix protein binding(GO:1990430)
0.0 0.2 GO:0019784 NEDD8-specific protease activity(GO:0019784)
0.0 0.1 GO:0004064 arylesterase activity(GO:0004064)
0.0 0.5 GO:0102391 decanoate--CoA ligase activity(GO:0102391)
0.0 0.4 GO:0008097 5S rRNA binding(GO:0008097)
0.0 0.1 GO:0003836 beta-galactoside (CMP) alpha-2,3-sialyltransferase activity(GO:0003836)
0.0 0.1 GO:0008454 alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity(GO:0008454)
0.0 0.1 GO:0047192 1-alkylglycerophosphocholine O-acetyltransferase activity(GO:0047192)
0.0 0.1 GO:0019166 trans-2-enoyl-CoA reductase (NADPH) activity(GO:0019166)
0.0 0.1 GO:0005483 soluble NSF attachment protein activity(GO:0005483)
0.0 0.1 GO:0004703 G-protein coupled receptor kinase activity(GO:0004703)
0.0 0.6 GO:0070006 metalloaminopeptidase activity(GO:0070006)
0.0 0.5 GO:0000900 translation repressor activity, nucleic acid binding(GO:0000900)
0.0 0.3 GO:0045294 alpha-catenin binding(GO:0045294)
0.0 0.1 GO:0015928 alpha-L-fucosidase activity(GO:0004560) fucosidase activity(GO:0015928)
0.0 0.1 GO:0050816 phosphothreonine binding(GO:0050816)
0.0 0.1 GO:0051525 NFAT protein binding(GO:0051525)
0.0 0.5 GO:0004129 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.0 0.1 GO:0070699 type II activin receptor binding(GO:0070699)
0.0 0.1 GO:0004525 ribonuclease III activity(GO:0004525) double-stranded RNA-specific ribonuclease activity(GO:0032296)
0.0 0.6 GO:0005504 fatty acid binding(GO:0005504)
0.0 0.4 GO:0033549 MAP kinase phosphatase activity(GO:0033549)
0.0 0.4 GO:0042043 neurexin family protein binding(GO:0042043)
0.0 0.7 GO:0005112 Notch binding(GO:0005112)
0.0 0.4 GO:0070628 proteasome binding(GO:0070628)
0.0 0.5 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.0 0.2 GO:0009931 calcium-dependent protein serine/threonine kinase activity(GO:0009931)
0.0 0.4 GO:0030215 semaphorin receptor binding(GO:0030215)
0.0 0.1 GO:0004303 estradiol 17-beta-dehydrogenase activity(GO:0004303)
0.0 0.9 GO:0019843 rRNA binding(GO:0019843)
0.0 0.3 GO:0004623 phospholipase A2 activity(GO:0004623)
0.0 0.2 GO:0019215 intermediate filament binding(GO:0019215)
0.0 0.1 GO:0004169 dolichyl-phosphate-mannose-protein mannosyltransferase activity(GO:0004169)
0.0 0.1 GO:0001665 alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity(GO:0001665)
0.0 0.2 GO:0070403 NAD+ binding(GO:0070403)
0.0 0.2 GO:0047372 acylglycerol lipase activity(GO:0047372)
0.0 0.3 GO:0050811 GABA-A receptor activity(GO:0004890) GABA receptor binding(GO:0050811)
0.0 0.1 GO:0043023 ribosomal large subunit binding(GO:0043023)
0.0 0.1 GO:0004691 cAMP-dependent protein kinase activity(GO:0004691)
0.0 0.4 GO:0008009 chemokine activity(GO:0008009)
0.0 0.0 GO:0001226 RNA polymerase II transcription corepressor binding(GO:0001226)
0.0 0.2 GO:0034987 immunoglobulin receptor binding(GO:0034987)
0.0 0.0 GO:0016716 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, another compound as one donor, and incorporation of one atom of oxygen(GO:0016716)
0.0 0.6 GO:0035035 histone acetyltransferase binding(GO:0035035)
0.0 0.3 GO:0046961 proton-transporting ATPase activity, rotational mechanism(GO:0046961)
0.0 0.2 GO:0005522 profilin binding(GO:0005522)
0.0 0.1 GO:0016701 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen(GO:0016701) oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen(GO:0016702)
0.0 0.2 GO:0004298 threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
0.0 0.1 GO:0031802 type 5 metabotropic glutamate receptor binding(GO:0031802)
0.0 0.0 GO:0016979 lipoate-protein ligase activity(GO:0016979)
0.0 0.2 GO:0004435 phosphatidylinositol phospholipase C activity(GO:0004435)
0.0 0.5 GO:0051059 NF-kappaB binding(GO:0051059)
0.0 0.0 GO:0045131 pre-mRNA branch point binding(GO:0045131)
0.0 0.2 GO:0008188 neuropeptide receptor activity(GO:0008188)
0.0 0.1 GO:0019104 DNA N-glycosylase activity(GO:0019104)
0.0 0.3 GO:0050136 NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.0 0.3 GO:0003785 actin monomer binding(GO:0003785)
0.0 0.1 GO:0004118 cGMP-stimulated cyclic-nucleotide phosphodiesterase activity(GO:0004118)
0.0 0.2 GO:0033130 acetylcholine receptor binding(GO:0033130)
0.0 0.1 GO:0004416 hydroxyacylglutathione hydrolase activity(GO:0004416)
0.0 0.1 GO:1990226 histone methyltransferase binding(GO:1990226)
0.0 0.2 GO:0005528 macrolide binding(GO:0005527) FK506 binding(GO:0005528)
0.0 1.2 GO:0001191 transcriptional repressor activity, RNA polymerase II transcription factor binding(GO:0001191)
0.0 0.0 GO:0003681 bent DNA binding(GO:0003681)
0.0 0.3 GO:0008139 nuclear localization sequence binding(GO:0008139)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.4 PID_PI3K_PLC_TRK_PATHWAY Trk receptor signaling mediated by PI3K and PLC-gamma
0.0 0.2 PID_THROMBIN_PAR4_PATHWAY PAR4-mediated thrombin signaling events
0.0 1.1 PID_CXCR3_PATHWAY CXCR3-mediated signaling events
0.0 0.8 ST_GA12_PATHWAY G alpha 12 Pathway
0.0 1.1 PID_DELTA_NP63_PATHWAY Validated transcriptional targets of deltaNp63 isoforms
0.0 0.1 SIG_PIP3_SIGNALING_IN_CARDIAC_MYOCTES Genes related to PIP3 signaling in cardiac myocytes
0.0 0.8 PID_SHP2_PATHWAY SHP2 signaling
0.0 0.6 PID_ANGIOPOIETIN_RECEPTOR_PATHWAY Angiopoietin receptor Tie2-mediated signaling
0.0 0.8 PID_RAS_PATHWAY Regulation of Ras family activation
0.0 0.4 PID_TAP63_PATHWAY Validated transcriptional targets of TAp63 isoforms
0.0 0.6 ST_ERK1_ERK2_MAPK_PATHWAY ERK1/ERK2 MAPK Pathway
0.0 3.5 PID_PDGFRB_PATHWAY PDGFR-beta signaling pathway
0.0 0.3 PID_NECTIN_PATHWAY Nectin adhesion pathway
0.0 0.6 PID_INTEGRIN_A4B1_PATHWAY Alpha4 beta1 integrin signaling events
0.0 0.2 PID_INTEGRIN5_PATHWAY Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.0 0.5 PID_BARD1_PATHWAY BARD1 signaling events
0.0 0.1 PID_TCR_CALCIUM_PATHWAY Calcium signaling in the CD4+ TCR pathway
0.0 0.3 PID_HDAC_CLASSIII_PATHWAY Signaling events mediated by HDAC Class III
0.0 0.4 PID_ERBB1_INTERNALIZATION_PATHWAY Internalization of ErbB1
0.0 0.7 PID_LKB1_PATHWAY LKB1 signaling events
0.0 1.3 NABA_ECM_AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.0 0.1 PID_IL2_STAT5_PATHWAY IL2 signaling events mediated by STAT5

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.9 REACTOME_REGULATION_OF_COMPLEMENT_CASCADE Genes involved in Regulation of Complement cascade
0.2 1.1 REACTOME_COMMON_PATHWAY Genes involved in Common Pathway
0.2 0.3 REACTOME_DSCAM_INTERACTIONS Genes involved in DSCAM interactions
0.1 0.8 REACTOME_CREATION_OF_C4_AND_C2_ACTIVATORS Genes involved in Creation of C4 and C2 activators
0.1 1.2 REACTOME_ERKS_ARE_INACTIVATED Genes involved in ERKs are inactivated
0.1 1.1 REACTOME_SIGNALING_BY_NOTCH2 Genes involved in Signaling by NOTCH2
0.1 0.2 REACTOME_EICOSANOID_LIGAND_BINDING_RECEPTORS Genes involved in Eicosanoid ligand-binding receptors
0.1 1.4 REACTOME_METABOLISM_OF_PORPHYRINS Genes involved in Metabolism of porphyrins
0.0 0.3 REACTOME_APOPTOTIC_CLEAVAGE_OF_CELL_ADHESION_PROTEINS Genes involved in Apoptotic cleavage of cell adhesion proteins
0.0 0.4 REACTOME_ACYL_CHAIN_REMODELLING_OF_PS Genes involved in Acyl chain remodelling of PS
0.0 0.7 REACTOME_SEMA3A_PLEXIN_REPULSION_SIGNALING_BY_INHIBITING_INTEGRIN_ADHESION Genes involved in SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion
0.0 0.4 REACTOME_ADVANCED_GLYCOSYLATION_ENDPRODUCT_RECEPTOR_SIGNALING Genes involved in Advanced glycosylation endproduct receptor signaling
0.0 0.7 REACTOME_ABCA_TRANSPORTERS_IN_LIPID_HOMEOSTASIS Genes involved in ABCA transporters in lipid homeostasis
0.0 0.3 REACTOME_P2Y_RECEPTORS Genes involved in P2Y receptors
0.0 0.7 REACTOME_FORMATION_OF_TUBULIN_FOLDING_INTERMEDIATES_BY_CCT_TRIC Genes involved in Formation of tubulin folding intermediates by CCT/TriC
0.0 0.4 REACTOME_REGULATION_OF_INSULIN_LIKE_GROWTH_FACTOR_IGF_ACTIVITY_BY_INSULIN_LIKE_GROWTH_FACTOR_BINDING_PROTEINS_IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.0 0.8 REACTOME_FRS2_MEDIATED_CASCADE Genes involved in FRS2-mediated cascade
0.0 2.7 REACTOME_TRANSPORT_OF_INORGANIC_CATIONS_ANIONS_AND_AMINO_ACIDS_OLIGOPEPTIDES Genes involved in Transport of inorganic cations/anions and amino acids/oligopeptides
0.0 0.3 REACTOME_APOPTOSIS_INDUCED_DNA_FRAGMENTATION Genes involved in Apoptosis induced DNA fragmentation
0.0 0.6 REACTOME_TIE2_SIGNALING Genes involved in Tie2 Signaling
0.0 0.2 REACTOME_REGULATION_OF_INSULIN_SECRETION_BY_ACETYLCHOLINE Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.0 0.7 REACTOME_ADHERENS_JUNCTIONS_INTERACTIONS Genes involved in Adherens junctions interactions
0.0 0.2 REACTOME_INTEGRIN_CELL_SURFACE_INTERACTIONS Genes involved in Integrin cell surface interactions
0.0 0.2 REACTOME_BASE_FREE_SUGAR_PHOSPHATE_REMOVAL_VIA_THE_SINGLE_NUCLEOTIDE_REPLACEMENT_PATHWAY Genes involved in Base-free sugar-phosphate removal via the single-nucleotide replacement pathway
0.0 1.7 REACTOME_PEPTIDE_LIGAND_BINDING_RECEPTORS Genes involved in Peptide ligand-binding receptors
0.0 0.2 REACTOME_TRAF6_MEDIATED_INDUCTION_OF_TAK1_COMPLEX Genes involved in TRAF6 mediated induction of TAK1 complex
0.0 0.3 REACTOME_ZINC_TRANSPORTERS Genes involved in Zinc transporters
0.0 0.4 REACTOME_ACTIVATED_NOTCH1_TRANSMITS_SIGNAL_TO_THE_NUCLEUS Genes involved in Activated NOTCH1 Transmits Signal to the Nucleus
0.0 0.3 REACTOME_SYNTHESIS_OF_SUBSTRATES_IN_N_GLYCAN_BIOSYTHESIS Genes involved in Synthesis of substrates in N-glycan biosythesis
0.0 1.7 REACTOME_PEPTIDE_CHAIN_ELONGATION Genes involved in Peptide chain elongation
0.0 0.2 REACTOME_SYNTHESIS_OF_PE Genes involved in Synthesis of PE
0.0 0.2 REACTOME_REGULATION_OF_IFNA_SIGNALING Genes involved in Regulation of IFNA signaling
0.0 0.2 REACTOME_COPI_MEDIATED_TRANSPORT Genes involved in COPI Mediated Transport
0.0 0.6 REACTOME_CA_DEPENDENT_EVENTS Genes involved in Ca-dependent events
0.0 0.1 REACTOME_G2_M_DNA_DAMAGE_CHECKPOINT Genes involved in G2/M DNA damage checkpoint
0.0 0.3 REACTOME_FANCONI_ANEMIA_PATHWAY Genes involved in Fanconi Anemia pathway
0.0 0.5 REACTOME_EGFR_DOWNREGULATION Genes involved in EGFR downregulation
0.0 0.2 REACTOME_PROCESSING_OF_INTRONLESS_PRE_MRNAS Genes involved in Processing of Intronless Pre-mRNAs
0.0 0.3 REACTOME_RAS_ACTIVATION_UOPN_CA2_INFUX_THROUGH_NMDA_RECEPTOR Genes involved in Ras activation uopn Ca2+ infux through NMDA receptor
0.0 0.2 REACTOME_ALPHA_LINOLENIC_ACID_ALA_METABOLISM Genes involved in alpha-linolenic acid (ALA) metabolism
0.0 0.3 REACTOME_SYNTHESIS_OF_PA Genes involved in Synthesis of PA
0.0 0.2 REACTOME_SYNTHESIS_OF_PIPS_AT_THE_GOLGI_MEMBRANE Genes involved in Synthesis of PIPs at the Golgi membrane
0.0 0.1 REACTOME_TERMINATION_OF_O_GLYCAN_BIOSYNTHESIS Genes involved in Termination of O-glycan biosynthesis
0.0 0.6 REACTOME_NCAM1_INTERACTIONS Genes involved in NCAM1 interactions
0.0 0.6 REACTOME_MITOCHONDRIAL_PROTEIN_IMPORT Genes involved in Mitochondrial Protein Import
0.0 0.1 REACTOME_FORMATION_OF_ATP_BY_CHEMIOSMOTIC_COUPLING Genes involved in Formation of ATP by chemiosmotic coupling
0.0 0.8 REACTOME_ASPARAGINE_N_LINKED_GLYCOSYLATION Genes involved in Asparagine N-linked glycosylation