Motif ID: Hcfc1_Six5_Smarcc2_Zfp143

Z-value: 2.471


Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Zfp143mm10_v2_chr7_+_110061702_1100617320.756.8e-08Click!
Hcfc1mm10_v2_chrX_-_73966329_739663760.463.9e-03Click!
Six5mm10_v2_chr7_+_19094594_190946330.353.3e-02Click!
Smarcc2mm10_v2_chr10_+_128459236_1284592480.325.3e-02Click!





Network of associatons between targets according to the STRING database.



First level regulatory network of Hcfc1_Six5_Smarcc2_Zfp143

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr4_+_116708571 15.070 ENSMUST00000106462.2
ENSMUST00000138305.1
ENSMUST00000125671.1
ENSMUST00000130828.1
Ccdc163



coiled-coil domain containing 163



chr4_+_116708624 13.775 ENSMUST00000106463.1
Ccdc163
coiled-coil domain containing 163
chr4_+_116708687 12.163 ENSMUST00000135499.1
Ccdc163
coiled-coil domain containing 163
chr4_+_116708467 9.831 ENSMUST00000030452.6
Ccdc163
coiled-coil domain containing 163
chr11_-_101551837 7.478 ENSMUST00000017290.4
Brca1
breast cancer 1
chr6_+_124829540 7.463 ENSMUST00000150120.1
Cdca3
cell division cycle associated 3
chr2_+_118598209 7.232 ENSMUST00000038341.7
Bub1b
budding uninhibited by benzimidazoles 1 homolog, beta (S. cerevisiae)
chr2_-_69206146 6.890 ENSMUST00000127243.1
ENSMUST00000149643.1
ENSMUST00000167875.2
ENSMUST00000005365.8
Spc25



SPC25, NDC80 kinetochore complex component, homolog (S. cerevisiae)



chr5_+_33658123 6.859 ENSMUST00000074849.6
ENSMUST00000079534.4
Tacc3

transforming, acidic coiled-coil containing protein 3

chr7_-_44997221 6.803 ENSMUST00000152341.1
Bcl2l12
BCL2-like 12 (proline rich)
chr2_+_152847961 6.765 ENSMUST00000164120.1
ENSMUST00000178997.1
ENSMUST00000109816.1
Tpx2


TPX2, microtubule-associated protein homolog (Xenopus laevis)


chr2_+_152847993 6.304 ENSMUST00000028969.8
Tpx2
TPX2, microtubule-associated protein homolog (Xenopus laevis)
chr14_-_64949632 6.226 ENSMUST00000176832.1
Hmbox1
homeobox containing 1
chr14_-_64949838 6.137 ENSMUST00000067843.3
ENSMUST00000176489.1
ENSMUST00000175905.1
ENSMUST00000022544.7
ENSMUST00000175744.1
ENSMUST00000176128.1
Hmbox1





homeobox containing 1





chr2_-_69206133 6.027 ENSMUST00000112320.1
Spc25
SPC25, NDC80 kinetochore complex component, homolog (S. cerevisiae)
chr11_+_117849223 5.984 ENSMUST00000081387.4
Birc5
baculoviral IAP repeat-containing 5
chr7_-_44997535 5.883 ENSMUST00000124232.1
ENSMUST00000003290.4
Bcl2l12

BCL2-like 12 (proline rich)

chrX_+_139684980 5.587 ENSMUST00000096313.3
Tbc1d8b
TBC1 domain family, member 8B
chr9_+_83548309 5.223 ENSMUST00000113215.3
Sh3bgrl2
SH3 domain binding glutamic acid-rich protein like 2
chr6_+_124829582 4.740 ENSMUST00000024270.7
Cdca3
cell division cycle associated 3
chr7_+_97332311 4.575 ENSMUST00000054107.5
Kctd21
potassium channel tetramerisation domain containing 21
chr4_-_117182623 4.445 ENSMUST00000065896.2
Kif2c
kinesin family member 2C
chr5_-_33657889 4.327 ENSMUST00000019439.7
Tmem129
transmembrane protein 129
chr5_-_5514730 3.906 ENSMUST00000115445.1
ENSMUST00000179804.1
ENSMUST00000125110.1
ENSMUST00000115446.1
Cldn12



claudin 12



chr11_+_117849286 3.863 ENSMUST00000093906.4
Birc5
baculoviral IAP repeat-containing 5
chr17_+_43667389 3.801 ENSMUST00000170988.1
Cyp39a1
cytochrome P450, family 39, subfamily a, polypeptide 1
chr11_+_61956779 3.785 ENSMUST00000049836.7
Specc1
sperm antigen with calponin homology and coiled-coil domains 1
chr16_-_55934797 3.770 ENSMUST00000122280.1
ENSMUST00000121703.2
Cep97

centrosomal protein 97

chr7_-_45092198 3.694 ENSMUST00000140449.1
ENSMUST00000117546.1
ENSMUST00000019683.3
Rcn3


reticulocalbin 3, EF-hand calcium binding domain


chr15_+_85859689 3.654 ENSMUST00000170629.1
Gtse1
G two S phase expressed protein 1
chr3_+_88081997 3.619 ENSMUST00000071812.5
Iqgap3
IQ motif containing GTPase activating protein 3
chr14_-_65833963 3.585 ENSMUST00000022613.9
Esco2
establishment of cohesion 1 homolog 2 (S. cerevisiae)
chr16_-_55934845 3.584 ENSMUST00000121129.1
ENSMUST00000023270.7
Cep97

centrosomal protein 97

chr9_-_72985344 3.524 ENSMUST00000124565.2
Gm5918
predicted gene 5918
chr4_+_126556935 3.470 ENSMUST00000048391.8
Clspn
claspin
chr4_+_49521176 3.373 ENSMUST00000042964.6
ENSMUST00000107696.1
Zfp189

zinc finger protein 189

chr14_+_64950037 3.340 ENSMUST00000043914.5
Ints9
integrator complex subunit 9
chr15_+_57912199 3.258 ENSMUST00000022992.6
Tbc1d31
TBC1 domain family, member 31
chr7_-_45092130 3.242 ENSMUST00000148175.1
Rcn3
reticulocalbin 3, EF-hand calcium binding domain
chr9_-_66126559 3.215 ENSMUST00000137542.1
Snx1
sorting nexin 1
chr3_+_89520152 3.188 ENSMUST00000000811.7
Kcnn3
potassium intermediate/small conductance calcium-activated channel, subfamily N, member 3
chr1_-_151428440 3.180 ENSMUST00000064771.5
Swt1
SWT1 RNA endoribonuclease homolog (S. cerevisiae)
chr15_+_102296256 3.156 ENSMUST00000064924.4
Espl1
extra spindle poles-like 1 (S. cerevisiae)
chr10_+_94036001 3.140 ENSMUST00000020208.4
Fgd6
FYVE, RhoGEF and PH domain containing 6
chr4_+_116807714 3.134 ENSMUST00000102699.1
ENSMUST00000130359.1
Mutyh

mutY homolog (E. coli)

chr7_+_118712516 3.110 ENSMUST00000106557.1
Ccp110
centriolar coiled coil protein 110
chr5_-_5514873 3.093 ENSMUST00000060947.7
Cldn12
claudin 12
chr13_+_112660739 3.070 ENSMUST00000052514.4
Slc38a9
solute carrier family 38, member 9
chr5_-_134314378 3.064 ENSMUST00000174867.1
Gtf2i
general transcription factor II I
chr11_+_69995777 3.014 ENSMUST00000018716.3
Phf23
PHD finger protein 23
chr1_-_58973421 3.007 ENSMUST00000173590.1
ENSMUST00000027186.5
Trak2

trafficking protein, kinesin binding 2

chr9_-_66919646 3.000 ENSMUST00000041139.7
Rab8b
RAB8B, member RAS oncogene family
chr3_+_87919490 2.980 ENSMUST00000019854.6
ENSMUST00000119968.1
Mrpl24

mitochondrial ribosomal protein L24

chr5_-_134314637 2.964 ENSMUST00000173504.1
Gtf2i
general transcription factor II I
chr5_-_149636331 2.950 ENSMUST00000074846.7
ENSMUST00000110498.1
ENSMUST00000127977.1
ENSMUST00000132412.1
Hsph1



heat shock 105kDa/110kDa protein 1



chr11_+_69995874 2.937 ENSMUST00000101526.2
Phf23
PHD finger protein 23
chr1_+_175880775 2.912 ENSMUST00000039725.6
Exo1
exonuclease 1
chrX_+_140956892 2.908 ENSMUST00000112971.1
Atg4a
autophagy related 4A, cysteine peptidase
chr19_-_10203880 2.898 ENSMUST00000142241.1
ENSMUST00000116542.2
ENSMUST00000025651.5
ENSMUST00000156291.1
Fen1



flap structure specific endonuclease 1



chr19_-_9899450 2.879 ENSMUST00000025562.7
Incenp
inner centromere protein
chr7_+_13278778 2.863 ENSMUST00000098814.4
ENSMUST00000146998.1
ENSMUST00000185145.1
Lig1


ligase I, DNA, ATP-dependent


chr4_-_119173849 2.855 ENSMUST00000052715.4
ENSMUST00000179290.1
ENSMUST00000154226.1
Zfp691


zinc finger protein 691


chr16_+_43889936 2.849 ENSMUST00000151183.1
2610015P09Rik
RIKEN cDNA 2610015P09 gene
chr5_-_148928619 2.818 ENSMUST00000149169.1
ENSMUST00000047257.8
Katnal1

katanin p60 subunit A-like 1

chr4_+_134396320 2.785 ENSMUST00000105869.2
Pafah2
platelet-activating factor acetylhydrolase 2
chr3_+_79629074 2.759 ENSMUST00000029388.8
4930579G24Rik
RIKEN cDNA 4930579G24 gene
chr1_+_151428612 2.746 ENSMUST00000065625.5
Trmt1l
tRNA methyltransferase 1 like
chr11_+_60699758 2.726 ENSMUST00000108719.3
Llgl1
lethal giant larvae homolog 1 (Drosophila)
chr18_-_24020307 2.680 ENSMUST00000153337.1
ENSMUST00000148525.1
Zfp191

zinc finger protein 191

chr3_+_87919563 2.673 ENSMUST00000121920.1
Mrpl24
mitochondrial ribosomal protein L24
chr4_-_132422394 2.661 ENSMUST00000152271.1
ENSMUST00000084170.5
Phactr4

phosphatase and actin regulator 4

chr10_-_100487316 2.641 ENSMUST00000134477.1
ENSMUST00000099318.3
ENSMUST00000058154.8
Tmtc3


transmembrane and tetratricopeptide repeat containing 3


chr7_+_44997648 2.620 ENSMUST00000003284.8
ENSMUST00000107835.1
Irf3

interferon regulatory factor 3

chr11_-_100527896 2.609 ENSMUST00000107389.1
ENSMUST00000007131.9
Acly

ATP citrate lyase

chr11_+_101552188 2.606 ENSMUST00000147239.1
Nbr1
neighbor of Brca1 gene 1
chr1_-_20820213 2.604 ENSMUST00000053266.9
Mcm3
minichromosome maintenance deficient 3 (S. cerevisiae)
chr4_-_119174178 2.603 ENSMUST00000106355.3
Zfp691
zinc finger protein 691
chrX_-_139998519 2.586 ENSMUST00000113007.1
ENSMUST00000033810.7
ENSMUST00000113011.2
ENSMUST00000087400.5
Rbm41



RNA binding motif protein 41



chr4_-_124936852 2.583 ENSMUST00000030690.5
ENSMUST00000084296.3
Cdca8

cell division cycle associated 8

chr1_+_156040884 2.581 ENSMUST00000060404.4
Tor1aip2
torsin A interacting protein 2
chr7_+_12897800 2.579 ENSMUST00000055528.4
ENSMUST00000117189.1
ENSMUST00000120809.1
ENSMUST00000119989.1
Zscan22



zinc finger and SCAN domain containing 22



chr19_+_53329413 2.572 ENSMUST00000025998.7
Mxi1
Max interacting protein 1
chr7_+_29768552 2.554 ENSMUST00000032802.4
Zfp84
zinc finger protein 84
chr18_-_24020749 2.545 ENSMUST00000066497.5
Zfp191
zinc finger protein 191
chr7_-_97332017 2.543 ENSMUST00000139582.2
Usp35
ubiquitin specific peptidase 35
chr10_-_100487267 2.540 ENSMUST00000128009.1
Tmtc3
transmembrane and tetratricopeptide repeat containing 3
chr13_+_44730726 2.537 ENSMUST00000173704.1
ENSMUST00000044608.7
ENSMUST00000173367.1
Jarid2


jumonji, AT rich interactive domain 2


chr17_-_23673825 2.521 ENSMUST00000115490.1
ENSMUST00000047436.4
ENSMUST00000138190.1
ENSMUST00000095579.4
Thoc6



THO complex 6 homolog (Drosophila)



chr10_-_81407641 2.516 ENSMUST00000140916.1
Nfic
nuclear factor I/C
chr11_+_60699718 2.510 ENSMUST00000052346.3
Llgl1
lethal giant larvae homolog 1 (Drosophila)
chr6_-_120038647 2.463 ENSMUST00000088646.5
ENSMUST00000177761.1
ENSMUST00000088644.6
ENSMUST00000060043.6
Wnk1



WNK lysine deficient protein kinase 1



chr19_-_41802028 2.456 ENSMUST00000026150.8
ENSMUST00000177495.1
ENSMUST00000163265.1
Arhgap19


Rho GTPase activating protein 19


chr4_-_132422484 2.401 ENSMUST00000102568.3
Phactr4
phosphatase and actin regulator 4
chr3_-_127780461 2.395 ENSMUST00000029662.5
ENSMUST00000161239.1
Alpk1

alpha-kinase 1

chr8_-_57487801 2.380 ENSMUST00000034022.3
Sap30
sin3 associated polypeptide
chr11_-_100527862 2.372 ENSMUST00000107385.1
Acly
ATP citrate lyase
chr12_+_79297345 2.371 ENSMUST00000079533.5
ENSMUST00000171210.1
Rad51b

RAD51 homolog B

chr9_+_66126611 2.359 ENSMUST00000034945.5
Fam96a
family with sequence similarity 96, member A
chr7_+_44468020 2.351 ENSMUST00000117324.1
ENSMUST00000120852.1
ENSMUST00000118628.1
Josd2


Josephin domain containing 2


chr2_+_52857844 2.351 ENSMUST00000090952.4
ENSMUST00000049483.6
ENSMUST00000050719.6
Fmnl2


formin-like 2


chr7_-_24208093 2.351 ENSMUST00000086006.5
Zfp111
zinc finger protein 111
chr4_+_126556994 2.350 ENSMUST00000147675.1
Clspn
claspin
chr5_+_34369909 2.344 ENSMUST00000180376.1
Fam193a
family with sequence similarity 193, member A
chr2_-_84727350 2.287 ENSMUST00000028475.8
Clp1
CLP1, cleavage and polyadenylation factor I subunit
chr16_+_43889896 2.278 ENSMUST00000122014.1
ENSMUST00000178400.1
2610015P09Rik

RIKEN cDNA 2610015P09 gene

chr9_+_118040509 2.272 ENSMUST00000133580.1
Azi2
5-azacytidine induced gene 2
chr11_+_98907801 2.248 ENSMUST00000092706.6
Cdc6
cell division cycle 6
chr4_-_151996113 2.248 ENSMUST00000055688.9
Phf13
PHD finger protein 13
chr2_-_145935014 2.184 ENSMUST00000001818.4
Crnkl1
Crn, crooked neck-like 1 (Drosophila)
chr2_-_38287174 2.183 ENSMUST00000130472.1
Dennd1a
DENN/MADD domain containing 1A
chr9_-_48480540 2.153 ENSMUST00000034524.3
Rexo2
REX2, RNA exonuclease 2 homolog (S. cerevisiae)
chr5_+_33658567 2.152 ENSMUST00000114426.3
Tacc3
transforming, acidic coiled-coil containing protein 3
chr7_-_128237984 2.129 ENSMUST00000078816.3
9130023H24Rik
RIKEN cDNA 9130023H24 gene
chr2_-_101628930 2.120 ENSMUST00000099682.2
B230118H07Rik
RIKEN cDNA B230118H07 gene
chr7_+_44467980 2.110 ENSMUST00000035844.4
Josd2
Josephin domain containing 2
chr12_+_106010263 2.104 ENSMUST00000021539.8
ENSMUST00000085026.4
ENSMUST00000072040.5
Vrk1


vaccinia related kinase 1


chr11_+_101552135 2.090 ENSMUST00000103099.1
Nbr1
neighbor of Brca1 gene 1
chr1_+_106171752 2.087 ENSMUST00000061047.6
Phlpp1
PH domain and leucine rich repeat protein phosphatase 1
chr14_-_56571830 2.084 ENSMUST00000065302.7
Cenpj
centromere protein J
chr9_+_118040576 2.063 ENSMUST00000134433.1
Azi2
5-azacytidine induced gene 2
chr6_+_95117740 2.045 ENSMUST00000032107.7
ENSMUST00000119582.1
Kbtbd8

kelch repeat and BTB (POZ) domain containing 8

chr7_+_7171330 2.038 ENSMUST00000051435.7
Zfp418
zinc finger protein 418
chr16_+_92301266 2.020 ENSMUST00000063641.4
ENSMUST00000118064.1
Smim11

small integral membrane protein 11

chr12_-_31950170 2.014 ENSMUST00000176520.1
Hbp1
high mobility group box transcription factor 1
chrX_-_162829379 2.006 ENSMUST00000041370.4
ENSMUST00000112316.2
ENSMUST00000112315.1
Txlng


taxilin gamma


chr15_-_34495180 1.976 ENSMUST00000022946.5
Hrsp12
heat-responsive protein 12
chr9_-_87255536 1.946 ENSMUST00000093802.4
4922501C03Rik
RIKEN cDNA 4922501C03 gene
chr7_+_44468051 1.934 ENSMUST00000118493.1
Josd2
Josephin domain containing 2
chr5_+_33658550 1.929 ENSMUST00000152847.1
Tacc3
transforming, acidic coiled-coil containing protein 3
chr7_+_30095150 1.925 ENSMUST00000130526.1
ENSMUST00000108200.1
Zfp260

zinc finger protein 260

chr4_-_128609981 1.925 ENSMUST00000141040.1
ENSMUST00000147876.1
ENSMUST00000097877.2
Zscan20


zinc finger and SCAN domains 20


chrX_+_101254528 1.907 ENSMUST00000062000.4
Foxo4
forkhead box O4
chr16_+_58727910 1.906 ENSMUST00000023426.5
ENSMUST00000162057.1
ENSMUST00000162191.1
Cldn25


claudin 25


chr16_-_91618986 1.899 ENSMUST00000143058.1
ENSMUST00000049244.8
ENSMUST00000169982.1
ENSMUST00000133731.1
Dnajc28



DnaJ (Hsp40) homolog, subfamily C, member 28



chr19_+_60889749 1.899 ENSMUST00000003313.8
Grk5
G protein-coupled receptor kinase 5
chr2_+_173021902 1.867 ENSMUST00000029014.9
Rbm38
RNA binding motif protein 38
chr12_-_31950210 1.858 ENSMUST00000176084.1
ENSMUST00000176103.1
ENSMUST00000167458.2
Hbp1


high mobility group box transcription factor 1


chr15_-_78773452 1.857 ENSMUST00000018313.5
Mfng
MFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase
chr5_-_134314678 1.837 ENSMUST00000174354.1
ENSMUST00000174155.1
ENSMUST00000174513.1
ENSMUST00000174772.1
ENSMUST00000173341.1
ENSMUST00000111261.4
ENSMUST00000082057.3
ENSMUST00000059042.7
Gtf2i







general transcription factor II I







chr11_+_45852031 1.835 ENSMUST00000109261.3
ENSMUST00000109260.1
Clint1

clathrin interactor 1

chr4_-_116708312 1.832 ENSMUST00000030453.4
Mmachc
methylmalonic aciduria cblC type, with homocystinuria
chr17_-_23673557 1.824 ENSMUST00000115489.1
Thoc6
THO complex 6 homolog (Drosophila)
chr1_+_131867224 1.805 ENSMUST00000112386.1
ENSMUST00000027693.7
Rab7l1

RAB7, member RAS oncogene family-like 1

chr2_-_77946180 1.802 ENSMUST00000111824.1
ENSMUST00000111819.1
ENSMUST00000128963.1
Cwc22


CWC22 spliceosome-associated protein homolog (S. cerevisiae)


chr5_+_134099704 1.788 ENSMUST00000016088.8
Gatsl2
GATS protein-like 2
chr2_+_119112793 1.774 ENSMUST00000140939.1
ENSMUST00000028795.3
Rad51

RAD51 homolog

chr13_-_54565299 1.770 ENSMUST00000153065.1
ENSMUST00000126295.1
ENSMUST00000143144.1
ENSMUST00000132136.1
4833439L19Rik



RIKEN cDNA 4833439L19 gene



chr10_-_40883073 1.762 ENSMUST00000044166.7
Cdc40
cell division cycle 40
chr12_-_91384403 1.755 ENSMUST00000141429.1
Cep128
centrosomal protein 128
chr16_+_43889800 1.747 ENSMUST00000132859.1
2610015P09Rik
RIKEN cDNA 2610015P09 gene
chr9_+_118040475 1.744 ENSMUST00000044454.5
Azi2
5-azacytidine induced gene 2
chr15_-_9140374 1.727 ENSMUST00000096482.3
ENSMUST00000110585.2
Skp2

S-phase kinase-associated protein 2 (p45)

chr7_+_29983948 1.711 ENSMUST00000148442.1
Zfp568
zinc finger protein 568
chr9_-_62510498 1.698 ENSMUST00000164246.2
Coro2b
coronin, actin binding protein, 2B
chr1_+_172481788 1.691 ENSMUST00000127052.1
Igsf9
immunoglobulin superfamily, member 9
chr2_-_165388245 1.676 ENSMUST00000103084.3
Zfp334
zinc finger protein 334
chr4_+_83417715 1.661 ENSMUST00000030206.3
ENSMUST00000071544.4
Snapc3

small nuclear RNA activating complex, polypeptide 3

chr5_+_110839973 1.651 ENSMUST00000066160.1
Chek2
checkpoint kinase 2
chr2_-_153241402 1.647 ENSMUST00000056924.7
Plagl2
pleiomorphic adenoma gene-like 2
chr15_-_102722150 1.639 ENSMUST00000023818.3
Calcoco1
calcium binding and coiled coil domain 1
chr6_+_21949571 1.633 ENSMUST00000031680.3
ENSMUST00000115389.1
ENSMUST00000151473.1
Ing3


inhibitor of growth family, member 3


chr17_+_80127447 1.621 ENSMUST00000039205.4
Galm
galactose mutarotase
chr7_+_100372224 1.617 ENSMUST00000051777.8
ENSMUST00000098259.4
C2cd3

C2 calcium-dependent domain containing 3

chr11_+_96789213 1.617 ENSMUST00000079702.3
Cbx1
chromobox 1
chr6_-_70792155 1.608 ENSMUST00000066134.5
Rpia
ribose 5-phosphate isomerase A
chr13_-_54565368 1.607 ENSMUST00000026989.8
4833439L19Rik
RIKEN cDNA 4833439L19 gene
chr13_-_12258093 1.606 ENSMUST00000099856.4
Mtr
5-methyltetrahydrofolate-homocysteine methyltransferase
chr15_+_34495302 1.605 ENSMUST00000052290.7
ENSMUST00000079028.5
Pop1

processing of precursor 1, ribonuclease P/MRP family, (S. cerevisiae)

chr5_+_138187485 1.599 ENSMUST00000110934.2
Cnpy4
canopy 4 homolog (zebrafish)
chr1_+_172482199 1.597 ENSMUST00000135267.1
ENSMUST00000052629.6
ENSMUST00000111235.2
Igsf9


immunoglobulin superfamily, member 9


chr4_+_48279794 1.583 ENSMUST00000030029.3
Invs
inversin
chr2_-_101628958 1.567 ENSMUST00000111231.3
B230118H07Rik
RIKEN cDNA B230118H07 gene
chr2_-_77946331 1.551 ENSMUST00000111821.2
ENSMUST00000111818.1
Cwc22

CWC22 spliceosome-associated protein homolog (S. cerevisiae)

chr7_-_128461327 1.541 ENSMUST00000033135.7
Tial1
Tia1 cytotoxic granule-associated RNA binding protein-like 1
chr2_+_155133501 1.524 ENSMUST00000029126.8
ENSMUST00000109685.1
Itch

itchy, E3 ubiquitin protein ligase

chr16_-_50432340 1.512 ENSMUST00000066037.6
ENSMUST00000089399.4
ENSMUST00000089404.3
ENSMUST00000114477.1
ENSMUST00000138166.1
Bbx




bobby sox homolog (Drosophila)




chr11_+_96789149 1.511 ENSMUST00000093943.3
Cbx1
chromobox 1
chr14_+_64652524 1.509 ENSMUST00000100473.4
Kif13b
kinesin family member 13B
chr11_-_70015346 1.508 ENSMUST00000018718.7
ENSMUST00000102574.3
Acadvl

acyl-Coenzyme A dehydrogenase, very long chain

chr4_-_62408618 1.482 ENSMUST00000107459.1
ENSMUST00000084525.5
Cdc26

cell division cycle 26

chr16_-_18811615 1.473 ENSMUST00000096990.3
Cdc45
cell division cycle 45
chr12_-_64965496 1.465 ENSMUST00000021331.7
Klhl28
kelch-like 28
chr13_-_67360509 1.463 ENSMUST00000081582.6
ENSMUST00000185002.1
Zfp953
ZFP953
zinc finger protein 953
Protein Zfp953
chr19_+_6334979 1.458 ENSMUST00000113504.3
ENSMUST00000113502.3
ENSMUST00000079327.5
ENSMUST00000056391.8
ENSMUST00000113501.1
ENSMUST00000113500.1
ENSMUST00000166909.1
Men1






multiple endocrine neoplasia 1






chr2_-_120850364 1.448 ENSMUST00000131389.1
Ttbk2
tau tubulin kinase 2
chr11_-_50887443 1.439 ENSMUST00000050595.6
ENSMUST00000163301.1
ENSMUST00000109131.1
ENSMUST00000125749.1
Zfp454



zinc finger protein 454



chr6_-_85333412 1.431 ENSMUST00000059034.6
ENSMUST00000045846.5
ENSMUST00000113788.1
Sfxn5


sideroflexin 5


chr6_-_120357440 1.423 ENSMUST00000112703.1
Ccdc77
coiled-coil domain containing 77
chr2_-_38287347 1.415 ENSMUST00000102787.3
Dennd1a
DENN/MADD domain containing 1A
chr19_+_6335093 1.411 ENSMUST00000078137.5
Men1
multiple endocrine neoplasia 1
chr17_+_47737030 1.410 ENSMUST00000086932.3
Tfeb
transcription factor EB
chr14_+_99099433 1.409 ENSMUST00000022650.7
Pibf1
progesterone immunomodulatory binding factor 1
chr2_-_77946375 1.404 ENSMUST00000065889.3
Cwc22
CWC22 spliceosome-associated protein homolog (S. cerevisiae)
chr4_-_41503046 1.385 ENSMUST00000054920.4
AI464131
expressed sequence AI464131
chr15_-_102722120 1.367 ENSMUST00000171838.1
Calcoco1
calcium binding and coiled coil domain 1
chr15_-_43869993 1.351 ENSMUST00000067469.4
Tmem74
transmembrane protein 74
chr11_+_101552849 1.341 ENSMUST00000107213.1
ENSMUST00000107208.1
ENSMUST00000107212.1
ENSMUST00000127421.1
Nbr1



neighbor of Brca1 gene 1



chr15_-_57892358 1.333 ENSMUST00000022993.5
Derl1
Der1-like domain family, member 1
chr7_+_12478319 1.330 ENSMUST00000151933.1
Zfp606
zinc finger protein 606
chr8_-_61591130 1.317 ENSMUST00000135439.1
ENSMUST00000121200.1
Palld

palladin, cytoskeletal associated protein


Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
2.5 7.5 GO:2000620 positive regulation of histone H4-K16 acetylation(GO:2000620)
2.4 7.2 GO:0051754 meiotic sister chromatid cohesion, centromeric(GO:0051754)
2.0 22.1 GO:1990001 inhibition of cysteine-type endopeptidase activity involved in apoptotic process(GO:1990001)
1.9 3.7 GO:0061511 centriole elongation(GO:0061511)
1.7 1.7 GO:2000002 negative regulation of DNA damage checkpoint(GO:2000002)
1.6 7.9 GO:0014886 transition between slow and fast fiber(GO:0014886)
1.5 6.1 GO:0044565 dendritic cell proliferation(GO:0044565)
1.3 6.5 GO:1901097 negative regulation of autophagosome maturation(GO:1901097)
1.3 5.1 GO:2001045 closure of optic fissure(GO:0061386) negative regulation of integrin-mediated signaling pathway(GO:2001045)
1.0 5.2 GO:0060447 bud outgrowth involved in lung branching(GO:0060447)
0.9 31.2 GO:0060236 regulation of mitotic spindle organization(GO:0060236)
0.9 4.4 GO:0030951 establishment or maintenance of microtubule cytoskeleton polarity(GO:0030951)
0.8 2.5 GO:0023016 signal transduction by trans-phosphorylation(GO:0023016)
0.8 5.6 GO:0033567 DNA replication, Okazaki fragment processing(GO:0033567)
0.8 2.3 GO:0036388 pre-replicative complex assembly involved in nuclear cell cycle DNA replication(GO:0006267) pre-replicative complex assembly(GO:0036388) DNA replication preinitiation complex assembly(GO:0071163) pre-replicative complex assembly involved in cell cycle DNA replication(GO:1902299)
0.8 3.1 GO:0032053 ciliary basal body organization(GO:0032053)
0.8 12.4 GO:0035563 positive regulation of chromatin binding(GO:0035563)
0.7 2.9 GO:0045343 MHC class I biosynthetic process(GO:0045341) regulation of MHC class I biosynthetic process(GO:0045343) positive regulation of MHC class I biosynthetic process(GO:0045345) positive regulation of NK T cell activation(GO:0051135)
0.7 3.6 GO:0034421 post-translational protein acetylation(GO:0034421)
0.7 3.6 GO:0002667 lymphocyte anergy(GO:0002249) regulation of T cell anergy(GO:0002667) T cell anergy(GO:0002870) regulation of lymphocyte anergy(GO:0002911)
0.7 5.2 GO:0042148 strand invasion(GO:0042148)
0.7 2.6 GO:0045358 negative regulation of interferon-beta biosynthetic process(GO:0045358)
0.7 3.3 GO:0051697 protein delipidation(GO:0051697)
0.6 3.9 GO:0032483 regulation of Rab protein signal transduction(GO:0032483)
0.6 5.8 GO:0033314 mitotic DNA replication checkpoint(GO:0033314)
0.6 3.4 GO:0009235 cobalamin metabolic process(GO:0009235)
0.6 5.0 GO:0010745 negative regulation of macrophage derived foam cell differentiation(GO:0010745)
0.5 1.5 GO:2000616 negative regulation of histone H3-K9 acetylation(GO:2000616)
0.5 1.9 GO:0007217 tachykinin receptor signaling pathway(GO:0007217)
0.5 1.4 GO:0009814 defense response, incompatible interaction(GO:0009814)
0.5 2.8 GO:0051013 microtubule severing(GO:0051013)
0.5 0.9 GO:0071921 establishment of sister chromatid cohesion(GO:0034085) cohesin loading(GO:0071921) regulation of cohesin loading(GO:0071922)
0.4 2.2 GO:0035405 histone-threonine phosphorylation(GO:0035405)
0.4 3.0 GO:0051461 regulation of corticotropin secretion(GO:0051459) positive regulation of corticotropin secretion(GO:0051461)
0.4 1.3 GO:0098968 neurotransmitter receptor transport postsynaptic membrane to endosome(GO:0098968)
0.4 1.3 GO:1903896 positive regulation of IRE1-mediated unfolded protein response(GO:1903896)
0.4 1.2 GO:0006553 lysine metabolic process(GO:0006553)
0.4 1.2 GO:0090526 regulation of gluconeogenesis involved in cellular glucose homeostasis(GO:0090526)
0.4 1.6 GO:0006014 D-ribose metabolic process(GO:0006014)
0.4 1.2 GO:0035574 histone H4-K20 demethylation(GO:0035574)
0.4 1.6 GO:0060971 embryonic heart tube left/right pattern formation(GO:0060971)
0.4 4.6 GO:0090435 protein localization to nuclear envelope(GO:0090435)
0.4 1.9 GO:1902916 positive regulation of protein polyubiquitination(GO:1902916)
0.4 3.8 GO:0016127 cholesterol catabolic process(GO:0006707) sterol catabolic process(GO:0016127)
0.4 1.1 GO:0070682 proteasome regulatory particle assembly(GO:0070682)
0.4 1.1 GO:0035864 response to potassium ion(GO:0035864) cellular response to potassium ion(GO:0035865)
0.4 3.6 GO:0033601 positive regulation of mammary gland epithelial cell proliferation(GO:0033601)
0.4 2.9 GO:0002051 osteoblast fate commitment(GO:0002051)
0.3 3.1 GO:0098937 dendritic transport(GO:0098935) anterograde dendritic transport(GO:0098937)
0.3 1.7 GO:0014022 neural plate elongation(GO:0014022) convergent extension involved in neural plate elongation(GO:0022007)
0.3 3.8 GO:0046784 viral mRNA export from host cell nucleus(GO:0046784)
0.3 3.9 GO:0007076 mitotic chromosome condensation(GO:0007076)
0.3 1.6 GO:0033499 galactose catabolic process via UDP-galactose(GO:0033499)
0.3 1.3 GO:0048633 positive regulation of skeletal muscle tissue growth(GO:0048633)
0.3 1.3 GO:0006742 NADP catabolic process(GO:0006742) pyridine nucleotide catabolic process(GO:0019364)
0.3 4.7 GO:0006107 oxaloacetate metabolic process(GO:0006107)
0.3 4.7 GO:0035090 maintenance of apical/basal cell polarity(GO:0035090)
0.3 1.2 GO:0000733 DNA strand renaturation(GO:0000733)
0.3 3.2 GO:0034498 early endosome to Golgi transport(GO:0034498)
0.3 1.4 GO:0006842 tricarboxylic acid transport(GO:0006842) citrate transport(GO:0015746)
0.3 2.5 GO:0051574 positive regulation of histone H3-K9 methylation(GO:0051574)
0.3 1.4 GO:0031392 regulation of prostaglandin biosynthetic process(GO:0031392) regulation of unsaturated fatty acid biosynthetic process(GO:2001279)
0.3 3.1 GO:0006977 DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest(GO:0006977)
0.3 2.8 GO:0016446 somatic hypermutation of immunoglobulin genes(GO:0016446)
0.3 1.9 GO:0035735 intraciliary transport involved in cilium morphogenesis(GO:0035735)
0.3 1.6 GO:0016078 tRNA catabolic process(GO:0016078)
0.3 1.0 GO:2001106 regulation of Rho guanyl-nucleotide exchange factor activity(GO:2001106)
0.3 3.6 GO:0006388 tRNA splicing, via endonucleolytic cleavage and ligation(GO:0006388)
0.3 1.0 GO:0030647 polyketide metabolic process(GO:0030638) aminoglycoside antibiotic metabolic process(GO:0030647) daunorubicin metabolic process(GO:0044597) doxorubicin metabolic process(GO:0044598)
0.3 1.0 GO:0044036 cell wall macromolecule metabolic process(GO:0044036) cell wall organization or biogenesis(GO:0071554)
0.3 0.8 GO:1903588 negative regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis(GO:1903588)
0.2 0.7 GO:0006546 glycine catabolic process(GO:0006546) glycine decarboxylation via glycine cleavage system(GO:0019464)
0.2 0.2 GO:0032240 negative regulation of nucleobase-containing compound transport(GO:0032240) negative regulation of RNA export from nucleus(GO:0046832)
0.2 1.9 GO:0051151 negative regulation of smooth muscle cell differentiation(GO:0051151)
0.2 0.7 GO:0036090 cleavage furrow ingression(GO:0036090)
0.2 3.7 GO:1990403 embryonic brain development(GO:1990403)
0.2 0.9 GO:0019919 peptidyl-arginine methylation, to asymmetrical-dimethyl arginine(GO:0019919)
0.2 2.6 GO:0046322 negative regulation of fatty acid oxidation(GO:0046322)
0.2 0.7 GO:0035621 ER to Golgi ceramide transport(GO:0035621) ceramide transport(GO:0035627)
0.2 1.1 GO:0071476 cellular hypotonic response(GO:0071476)
0.2 1.1 GO:0006564 L-serine biosynthetic process(GO:0006564)
0.2 2.1 GO:0000920 cell separation after cytokinesis(GO:0000920)
0.2 0.2 GO:0034140 negative regulation of toll-like receptor 3 signaling pathway(GO:0034140)
0.2 0.6 GO:2000312 regulation of kainate selective glutamate receptor activity(GO:2000312)
0.2 0.6 GO:0060399 positive regulation of growth hormone receptor signaling pathway(GO:0060399)
0.2 3.9 GO:0007080 mitotic metaphase plate congression(GO:0007080)
0.2 0.2 GO:0072069 DCT cell differentiation(GO:0072069) metanephric DCT cell differentiation(GO:0072240)
0.2 3.0 GO:0000212 meiotic spindle organization(GO:0000212)
0.2 0.8 GO:0035720 intraciliary anterograde transport(GO:0035720)
0.2 0.6 GO:2000766 negative regulation of cytoplasmic translation(GO:2000766)
0.2 1.0 GO:0051315 attachment of mitotic spindle microtubules to kinetochore(GO:0051315)
0.2 1.0 GO:0006777 Mo-molybdopterin cofactor biosynthetic process(GO:0006777) Mo-molybdopterin cofactor metabolic process(GO:0019720)
0.2 0.6 GO:0000389 mRNA 3'-splice site recognition(GO:0000389)
0.2 1.9 GO:0002315 marginal zone B cell differentiation(GO:0002315)
0.2 1.5 GO:0031145 anaphase-promoting complex-dependent catabolic process(GO:0031145)
0.2 0.7 GO:1902774 late endosome to lysosome transport(GO:1902774)
0.2 0.9 GO:0045743 positive regulation of fibroblast growth factor receptor signaling pathway(GO:0045743)
0.2 1.1 GO:0010730 negative regulation of hydrogen peroxide metabolic process(GO:0010727) negative regulation of hydrogen peroxide biosynthetic process(GO:0010730)
0.2 0.2 GO:0061470 T follicular helper cell differentiation(GO:0061470)
0.2 0.3 GO:0051292 nuclear pore complex assembly(GO:0051292)
0.2 11.2 GO:0007052 mitotic spindle organization(GO:0007052)
0.2 1.9 GO:0000301 retrograde transport, vesicle recycling within Golgi(GO:0000301)
0.2 0.9 GO:0001561 fatty acid alpha-oxidation(GO:0001561)
0.2 2.7 GO:0051085 chaperone mediated protein folding requiring cofactor(GO:0051085)
0.2 3.0 GO:0016180 snRNA processing(GO:0016180)
0.2 1.2 GO:0019370 leukotriene biosynthetic process(GO:0019370)
0.2 1.0 GO:0036066 protein O-linked fucosylation(GO:0036066)
0.2 1.3 GO:0001833 inner cell mass cell proliferation(GO:0001833)
0.2 1.3 GO:0070940 dephosphorylation of RNA polymerase II C-terminal domain(GO:0070940)
0.2 0.9 GO:0048793 pronephros development(GO:0048793)
0.2 1.4 GO:0009301 snRNA transcription(GO:0009301)
0.2 1.4 GO:0090209 negative regulation of triglyceride metabolic process(GO:0090209)
0.2 5.0 GO:0006270 DNA replication initiation(GO:0006270)
0.1 0.4 GO:0055099 response to high density lipoprotein particle(GO:0055099)
0.1 0.6 GO:1902037 negative regulation of hematopoietic stem cell differentiation(GO:1902037)
0.1 1.0 GO:0034145 positive regulation of toll-like receptor 4 signaling pathway(GO:0034145)
0.1 0.6 GO:0090168 Golgi reassembly(GO:0090168)
0.1 0.3 GO:1904192 cholangiocyte apoptotic process(GO:1902488) regulation of cholangiocyte apoptotic process(GO:1904192) negative regulation of cholangiocyte apoptotic process(GO:1904193)
0.1 1.6 GO:0014029 neural crest formation(GO:0014029)
0.1 0.4 GO:1903644 regulation of chaperone-mediated protein folding(GO:1903644)
0.1 2.3 GO:0032516 positive regulation of phosphoprotein phosphatase activity(GO:0032516)
0.1 0.5 GO:0046726 positive regulation by virus of viral protein levels in host cell(GO:0046726)
0.1 0.4 GO:0002184 cytoplasmic translational termination(GO:0002184)
0.1 0.6 GO:0036508 protein deglycosylation involved in glycoprotein catabolic process(GO:0035977) protein demannosylation(GO:0036507) protein alpha-1,2-demannosylation(GO:0036508) glycoprotein ERAD pathway(GO:0097466) mannose trimming involved in glycoprotein ERAD pathway(GO:1904382)
0.1 1.0 GO:0033564 anterior/posterior axon guidance(GO:0033564)
0.1 1.1 GO:2000051 negative regulation of non-canonical Wnt signaling pathway(GO:2000051)
0.1 1.3 GO:0043568 positive regulation of insulin-like growth factor receptor signaling pathway(GO:0043568)
0.1 0.5 GO:0031581 hemidesmosome assembly(GO:0031581)
0.1 0.6 GO:0089700 protein kinase D signaling(GO:0089700)
0.1 0.4 GO:0060912 cardiac cell fate specification(GO:0060912)
0.1 1.2 GO:0043173 nucleotide salvage(GO:0043173)
0.1 0.7 GO:0032308 positive regulation of prostaglandin secretion(GO:0032308)
0.1 0.6 GO:0010992 ubiquitin homeostasis(GO:0010992)
0.1 1.2 GO:1903351 response to dopamine(GO:1903350) cellular response to dopamine(GO:1903351)
0.1 0.2 GO:0006116 NADH oxidation(GO:0006116)
0.1 0.2 GO:1905154 negative regulation of membrane invagination(GO:1905154)
0.1 8.0 GO:0030500 regulation of bone mineralization(GO:0030500)
0.1 0.4 GO:0072015 glomerular visceral epithelial cell development(GO:0072015) glomerular epithelial cell development(GO:0072310)
0.1 0.8 GO:0030242 pexophagy(GO:0030242)
0.1 0.3 GO:0000414 regulation of histone H3-K36 methylation(GO:0000414)
0.1 0.6 GO:0034773 histone H4-K20 trimethylation(GO:0034773) establishment of Sertoli cell barrier(GO:0097368)
0.1 0.5 GO:1905076 regulation of interleukin-17 secretion(GO:1905076)
0.1 0.6 GO:0032202 telomere assembly(GO:0032202)
0.1 0.9 GO:0048341 paraxial mesoderm formation(GO:0048341)
0.1 0.4 GO:0046501 protoporphyrinogen IX metabolic process(GO:0046501)
0.1 0.5 GO:1901098 positive regulation of autophagosome maturation(GO:1901098)
0.1 0.8 GO:0007016 cytoskeletal anchoring at plasma membrane(GO:0007016)
0.1 0.1 GO:0006272 leading strand elongation(GO:0006272)
0.1 3.4 GO:0003333 amino acid transmembrane transport(GO:0003333)
0.1 1.3 GO:0034377 plasma lipoprotein particle assembly(GO:0034377)
0.1 1.0 GO:0006488 dolichol-linked oligosaccharide biosynthetic process(GO:0006488)
0.1 0.4 GO:0060334 regulation of interferon-gamma-mediated signaling pathway(GO:0060334)
0.1 0.4 GO:0006409 tRNA export from nucleus(GO:0006409) tRNA-containing ribonucleoprotein complex export from nucleus(GO:0071431)
0.1 0.6 GO:0033119 negative regulation of RNA splicing(GO:0033119)
0.1 1.1 GO:0060009 Sertoli cell development(GO:0060009)
0.1 0.2 GO:0000720 pyrimidine dimer repair by nucleotide-excision repair(GO:0000720)
0.1 0.7 GO:1900262 regulation of DNA-directed DNA polymerase activity(GO:1900262) positive regulation of DNA-directed DNA polymerase activity(GO:1900264)
0.1 0.3 GO:0035795 negative regulation of mitochondrial membrane permeability(GO:0035795)
0.1 0.1 GO:0015822 ornithine transport(GO:0015822)
0.1 2.5 GO:0010960 magnesium ion homeostasis(GO:0010960)
0.1 0.1 GO:0045716 positive regulation of low-density lipoprotein particle receptor biosynthetic process(GO:0045716)
0.1 0.3 GO:0097211 response to gonadotropin-releasing hormone(GO:0097210) cellular response to gonadotropin-releasing hormone(GO:0097211)
0.1 1.3 GO:0033539 fatty acid beta-oxidation using acyl-CoA dehydrogenase(GO:0033539)
0.1 0.7 GO:0018344 protein geranylgeranylation(GO:0018344)
0.1 0.6 GO:0034351 negative regulation of glial cell apoptotic process(GO:0034351)
0.1 0.2 GO:0035359 negative regulation of peroxisome proliferator activated receptor signaling pathway(GO:0035359)
0.1 1.3 GO:0003334 keratinocyte development(GO:0003334)
0.1 2.4 GO:0030970 retrograde protein transport, ER to cytosol(GO:0030970)
0.1 0.7 GO:0060736 prostate gland growth(GO:0060736)
0.1 0.1 GO:0030043 actin filament fragmentation(GO:0030043)
0.1 0.3 GO:0008655 pyrimidine-containing compound salvage(GO:0008655) pyrimidine nucleoside salvage(GO:0043097)
0.1 0.6 GO:0006297 nucleotide-excision repair, DNA gap filling(GO:0006297)
0.1 1.5 GO:0006607 NLS-bearing protein import into nucleus(GO:0006607)
0.1 0.7 GO:0044336 canonical Wnt signaling pathway involved in negative regulation of apoptotic process(GO:0044336)
0.1 0.7 GO:0080009 mRNA methylation(GO:0080009)
0.1 2.1 GO:0001893 maternal placenta development(GO:0001893)
0.1 1.4 GO:0043968 histone H2A acetylation(GO:0043968)
0.1 0.2 GO:1901187 regulation of ephrin receptor signaling pathway(GO:1901187)
0.1 0.4 GO:0061086 negative regulation of histone H3-K27 methylation(GO:0061086) positive regulation of histone H3-K27 methylation(GO:0061087)
0.1 0.3 GO:0060340 positive regulation of type I interferon-mediated signaling pathway(GO:0060340)
0.1 1.8 GO:0048268 clathrin coat assembly(GO:0048268)
0.1 0.7 GO:0032471 negative regulation of endoplasmic reticulum calcium ion concentration(GO:0032471) positive regulation of mitochondrial calcium ion concentration(GO:0051561)
0.1 0.3 GO:0010808 positive regulation of synaptic vesicle priming(GO:0010808)
0.1 0.9 GO:0032927 positive regulation of activin receptor signaling pathway(GO:0032927)
0.1 0.2 GO:0043686 co-translational protein modification(GO:0043686)
0.1 1.4 GO:0044253 positive regulation of collagen metabolic process(GO:0010714) positive regulation of multicellular organismal metabolic process(GO:0044253)
0.1 0.3 GO:0000480 endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000480)
0.1 0.8 GO:0007530 sex determination(GO:0007530)
0.1 0.4 GO:0051045 negative regulation of membrane protein ectodomain proteolysis(GO:0051045)
0.1 0.7 GO:0019368 fatty acid elongation, saturated fatty acid(GO:0019367) fatty acid elongation, unsaturated fatty acid(GO:0019368) fatty acid elongation, monounsaturated fatty acid(GO:0034625) fatty acid elongation, polyunsaturated fatty acid(GO:0034626)
0.1 0.9 GO:0090261 positive regulation of inclusion body assembly(GO:0090261)
0.1 0.1 GO:0016080 synaptic vesicle targeting(GO:0016080)
0.1 0.2 GO:0006751 glutathione catabolic process(GO:0006751)
0.1 0.4 GO:0030579 ubiquitin-dependent SMAD protein catabolic process(GO:0030579)
0.1 0.6 GO:0070072 vacuolar proton-transporting V-type ATPase complex assembly(GO:0070072)
0.1 0.1 GO:2001160 regulation of histone H3-K79 methylation(GO:2001160)
0.1 0.2 GO:2001271 negative regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:2001271)
0.1 0.3 GO:0010747 positive regulation of plasma membrane long-chain fatty acid transport(GO:0010747)
0.1 0.8 GO:1904262 negative regulation of TORC1 signaling(GO:1904262)
0.1 1.2 GO:1902751 positive regulation of cell cycle G2/M phase transition(GO:1902751)
0.1 0.2 GO:0048209 regulation of vesicle targeting, to, from or within Golgi(GO:0048209)
0.1 0.7 GO:0031573 intra-S DNA damage checkpoint(GO:0031573)
0.1 0.4 GO:0032020 ISG15-protein conjugation(GO:0032020)
0.1 0.7 GO:0006103 2-oxoglutarate metabolic process(GO:0006103)
0.0 0.1 GO:0006868 glutamine transport(GO:0006868)
0.0 2.8 GO:0042475 odontogenesis of dentin-containing tooth(GO:0042475)
0.0 0.1 GO:0019085 early viral transcription(GO:0019085)
0.0 0.7 GO:0070102 interleukin-6-mediated signaling pathway(GO:0070102)
0.0 0.2 GO:0072553 terminal button organization(GO:0072553)
0.0 4.5 GO:0090630 activation of GTPase activity(GO:0090630)
0.0 0.2 GO:0008616 queuosine biosynthetic process(GO:0008616) queuosine metabolic process(GO:0046116)
0.0 0.3 GO:0097428 protein maturation by iron-sulfur cluster transfer(GO:0097428)
0.0 0.8 GO:0009081 branched-chain amino acid metabolic process(GO:0009081) branched-chain amino acid catabolic process(GO:0009083)
0.0 0.3 GO:0016266 O-glycan processing(GO:0016266)
0.0 1.0 GO:0070979 protein K11-linked ubiquitination(GO:0070979)
0.0 0.2 GO:0038032 termination of G-protein coupled receptor signaling pathway(GO:0038032)
0.0 0.1 GO:0010520 regulation of reciprocal meiotic recombination(GO:0010520) positive regulation of reciprocal meiotic recombination(GO:0010845)
0.0 0.6 GO:0010447 response to acidic pH(GO:0010447)
0.0 0.4 GO:0018206 peptidyl-methionine modification(GO:0018206)
0.0 1.6 GO:0061512 protein localization to cilium(GO:0061512)
0.0 0.5 GO:1902857 positive regulation of nonmotile primary cilium assembly(GO:1902857)
0.0 0.1 GO:0009446 putrescine biosynthetic process(GO:0009446)
0.0 0.4 GO:0051967 negative regulation of synaptic transmission, glutamatergic(GO:0051967)
0.0 0.0 GO:1990009 retinal cell apoptotic process(GO:1990009)
0.0 0.2 GO:0035457 cellular response to interferon-alpha(GO:0035457)
0.0 0.2 GO:0019276 UDP-N-acetylgalactosamine metabolic process(GO:0019276)
0.0 0.0 GO:0030997 regulation of centriole-centriole cohesion(GO:0030997)
0.0 0.5 GO:0070935 3'-UTR-mediated mRNA stabilization(GO:0070935)
0.0 0.2 GO:0030091 protein repair(GO:0030091)
0.0 0.3 GO:1903551 regulation of extracellular exosome assembly(GO:1903551)
0.0 0.6 GO:0042532 negative regulation of tyrosine phosphorylation of STAT protein(GO:0042532)
0.0 2.3 GO:0035914 skeletal muscle cell differentiation(GO:0035914)
0.0 0.2 GO:0021747 cochlear nucleus development(GO:0021747) regulation of cargo loading into COPII-coated vesicle(GO:1901301)
0.0 0.8 GO:0070936 protein K48-linked ubiquitination(GO:0070936)
0.0 0.8 GO:0030866 cortical actin cytoskeleton organization(GO:0030866)
0.0 0.3 GO:0006398 mRNA 3'-end processing by stem-loop binding and cleavage(GO:0006398)
0.0 0.2 GO:0034080 CENP-A containing nucleosome assembly(GO:0034080) CENP-A containing chromatin organization(GO:0061641)
0.0 1.1 GO:0035307 positive regulation of protein dephosphorylation(GO:0035307)
0.0 0.1 GO:1904729 regulation of intestinal cholesterol absorption(GO:0030300) negative regulation of intestinal absorption(GO:1904479) regulation of intestinal lipid absorption(GO:1904729)
0.0 0.4 GO:0097194 execution phase of apoptosis(GO:0097194)
0.0 0.4 GO:0006516 glycoprotein catabolic process(GO:0006516)
0.0 0.7 GO:0034508 centromere complex assembly(GO:0034508)
0.0 3.1 GO:0000910 cytokinesis(GO:0000910)
0.0 0.3 GO:0030865 cortical cytoskeleton organization(GO:0030865)
0.0 4.0 GO:0016579 protein deubiquitination(GO:0016579)
0.0 9.2 GO:0000375 RNA splicing, via transesterification reactions(GO:0000375)
0.0 0.1 GO:0018242 protein O-linked glycosylation via serine(GO:0018242)
0.0 0.2 GO:1900246 positive regulation of RIG-I signaling pathway(GO:1900246)
0.0 0.1 GO:0071034 CUT catabolic process(GO:0071034) CUT metabolic process(GO:0071043)
0.0 0.4 GO:0007250 activation of NF-kappaB-inducing kinase activity(GO:0007250)
0.0 0.4 GO:0044458 motile cilium assembly(GO:0044458)
0.0 0.0 GO:0035306 positive regulation of dephosphorylation(GO:0035306)
0.0 0.7 GO:0045663 positive regulation of myoblast differentiation(GO:0045663)
0.0 0.6 GO:0007520 myoblast fusion(GO:0007520)
0.0 0.4 GO:0045948 positive regulation of translational initiation(GO:0045948)
0.0 0.3 GO:0071378 growth hormone receptor signaling pathway(GO:0060396) cellular response to growth hormone stimulus(GO:0071378)
0.0 0.3 GO:0080182 histone H3-K4 trimethylation(GO:0080182)
0.0 0.2 GO:2000210 positive regulation of anoikis(GO:2000210)
0.0 0.1 GO:0045003 DNA recombinase assembly(GO:0000730) double-strand break repair via synthesis-dependent strand annealing(GO:0045003)
0.0 0.1 GO:2001286 regulation of caveolin-mediated endocytosis(GO:2001286)
0.0 0.4 GO:0016226 iron-sulfur cluster assembly(GO:0016226) metallo-sulfur cluster assembly(GO:0031163)
0.0 0.4 GO:2001256 regulation of store-operated calcium entry(GO:2001256)
0.0 0.5 GO:0030150 protein import into mitochondrial matrix(GO:0030150)
0.0 0.3 GO:0045899 positive regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0045899)
0.0 1.7 GO:0051865 protein autoubiquitination(GO:0051865)
0.0 1.4 GO:0006367 transcription initiation from RNA polymerase II promoter(GO:0006367)
0.0 0.3 GO:0045742 positive regulation of epidermal growth factor receptor signaling pathway(GO:0045742) positive regulation of ERBB signaling pathway(GO:1901186)
0.0 1.2 GO:0006940 regulation of smooth muscle contraction(GO:0006940)
0.0 2.2 GO:0006821 chloride transport(GO:0006821)
0.0 0.1 GO:0001306 age-dependent response to oxidative stress(GO:0001306) age-dependent general metabolic decline(GO:0007571)
0.0 0.1 GO:2001032 regulation of double-strand break repair via nonhomologous end joining(GO:2001032)
0.0 0.8 GO:0043550 regulation of lipid kinase activity(GO:0043550)
0.0 0.5 GO:0035855 megakaryocyte development(GO:0035855)
0.0 2.0 GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)
0.0 0.7 GO:0000413 protein peptidyl-prolyl isomerization(GO:0000413)
0.0 0.3 GO:0019184 nonribosomal peptide biosynthetic process(GO:0019184)
0.0 0.1 GO:0006659 phosphatidylserine biosynthetic process(GO:0006659)
0.0 0.2 GO:0097094 craniofacial suture morphogenesis(GO:0097094)
0.0 0.1 GO:1903800 positive regulation of production of miRNAs involved in gene silencing by miRNA(GO:1903800)
0.0 0.1 GO:0048133 germ-line stem cell division(GO:0042078) male germ-line stem cell asymmetric division(GO:0048133) germline stem cell asymmetric division(GO:0098728)
0.0 0.4 GO:0060746 parental behavior(GO:0060746)
0.0 0.1 GO:0006657 CDP-choline pathway(GO:0006657)
0.0 0.2 GO:0032460 negative regulation of protein oligomerization(GO:0032460) negative regulation of protein homooligomerization(GO:0032463)
0.0 0.1 GO:0008050 inter-male aggressive behavior(GO:0002121) female courtship behavior(GO:0008050)
0.0 0.4 GO:0034605 cellular response to heat(GO:0034605)
0.0 0.1 GO:0010792 DNA double-strand break processing involved in repair via single-strand annealing(GO:0010792)
0.0 0.1 GO:0071596 ubiquitin-dependent protein catabolic process via the N-end rule pathway(GO:0071596)
0.0 0.3 GO:0006264 mitochondrial DNA replication(GO:0006264)
0.0 0.3 GO:0019430 removal of superoxide radicals(GO:0019430) cellular oxidant detoxification(GO:0098869)
0.0 1.3 GO:0007368 determination of left/right symmetry(GO:0007368)
0.0 0.1 GO:0034088 maintenance of sister chromatid cohesion(GO:0034086) maintenance of mitotic sister chromatid cohesion(GO:0034088)
0.0 0.3 GO:0032933 response to sterol depletion(GO:0006991) SREBP signaling pathway(GO:0032933) cellular response to sterol depletion(GO:0071501)
0.0 0.1 GO:0044130 negative regulation of growth of symbiont in host(GO:0044130) negative regulation of growth of symbiont involved in interaction with host(GO:0044146)
0.0 0.6 GO:0006284 base-excision repair(GO:0006284)
0.0 0.4 GO:0045494 photoreceptor cell maintenance(GO:0045494)
0.0 2.6 GO:0042113 B cell activation(GO:0042113)
0.0 0.3 GO:0031100 organ regeneration(GO:0031100)
0.0 0.2 GO:0010212 response to ionizing radiation(GO:0010212)
0.0 0.1 GO:0071397 cellular response to cholesterol(GO:0071397)
0.0 0.0 GO:0045911 positive regulation of DNA recombination(GO:0045911)
0.0 0.1 GO:0019254 carnitine metabolic process, CoA-linked(GO:0019254)
0.0 0.1 GO:0060040 retinal bipolar neuron differentiation(GO:0060040)
0.0 2.2 GO:0035023 regulation of Rho protein signal transduction(GO:0035023)
0.0 0.2 GO:0006767 water-soluble vitamin metabolic process(GO:0006767)
0.0 0.6 GO:0030512 negative regulation of transforming growth factor beta receptor signaling pathway(GO:0030512) negative regulation of cellular response to transforming growth factor beta stimulus(GO:1903845)
0.0 0.2 GO:0043486 histone exchange(GO:0043486)
0.0 0.0 GO:0046104 thymidine metabolic process(GO:0046104) deoxyribonucleoside catabolic process(GO:0046121)
0.0 0.5 GO:0007051 spindle organization(GO:0007051)
0.0 0.6 GO:0035904 aorta development(GO:0035904)
0.0 0.2 GO:0010667 negative regulation of cardiac muscle cell apoptotic process(GO:0010667)
0.0 0.2 GO:0046827 positive regulation of protein export from nucleus(GO:0046827)
0.0 0.4 GO:0030488 tRNA methylation(GO:0030488)
0.0 0.2 GO:0006895 Golgi to endosome transport(GO:0006895) response to interferon-alpha(GO:0035455)
0.0 0.1 GO:0030322 stabilization of membrane potential(GO:0030322)
0.0 0.1 GO:0006265 DNA topological change(GO:0006265)
0.0 0.5 GO:0051966 regulation of synaptic transmission, glutamatergic(GO:0051966)
0.0 0.3 GO:0099517 anterograde synaptic vesicle transport(GO:0048490) synaptic vesicle cytoskeletal transport(GO:0099514) synaptic vesicle transport along microtubule(GO:0099517)
0.0 0.4 GO:1901992 positive regulation of mitotic cell cycle phase transition(GO:1901992)
0.0 0.1 GO:2000144 positive regulation of DNA-templated transcription, initiation(GO:2000144)
0.0 0.1 GO:0007216 G-protein coupled glutamate receptor signaling pathway(GO:0007216)
0.0 0.2 GO:0070208 protein heterotrimerization(GO:0070208)
0.0 0.2 GO:0048820 hair follicle maturation(GO:0048820)
0.0 0.1 GO:0000055 ribosomal large subunit export from nucleus(GO:0000055)
0.0 2.1 GO:0016042 lipid catabolic process(GO:0016042)
0.0 0.5 GO:0003382 epithelial cell morphogenesis(GO:0003382)
0.0 0.1 GO:0035542 regulation of SNARE complex assembly(GO:0035542)
0.0 3.6 GO:0051301 cell division(GO:0051301)
0.0 0.1 GO:0031584 activation of phospholipase D activity(GO:0031584)
0.0 0.2 GO:0006346 methylation-dependent chromatin silencing(GO:0006346)
0.0 0.1 GO:0006907 pinocytosis(GO:0006907)
0.0 0.3 GO:0036075 endochondral ossification(GO:0001958) replacement ossification(GO:0036075)
0.0 0.1 GO:0008088 axo-dendritic transport(GO:0008088)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
2.5 12.4 GO:0032133 chromosome passenger complex(GO:0032133)
2.2 12.9 GO:0031262 Ndc80 complex(GO:0031262)
1.6 13.1 GO:0005818 aster(GO:0005818)
1.2 7.5 GO:0070531 BRCA1-A complex(GO:0070531)
1.2 4.8 GO:0071006 U2-type catalytic step 1 spliceosome(GO:0071006)
1.1 3.2 GO:0030905 retromer, tubulation complex(GO:0030905)
1.1 1.1 GO:0070552 BRISC complex(GO:0070552)
0.9 2.8 GO:0000801 central element(GO:0000801)
0.8 2.3 GO:0036387 nuclear pre-replicative complex(GO:0005656) pre-replicative complex(GO:0036387)
0.7 2.2 GO:1990423 RZZ complex(GO:1990423)
0.7 2.2 GO:0071012 catalytic step 1 spliceosome(GO:0071012)
0.7 9.2 GO:0000778 condensed nuclear chromosome kinetochore(GO:0000778)
0.6 4.4 GO:0001940 male pronucleus(GO:0001940)
0.6 3.6 GO:0000214 tRNA-intron endonuclease complex(GO:0000214)
0.5 1.6 GO:0097543 ciliary inversin compartment(GO:0097543)
0.5 2.6 GO:0033063 Rad51B-Rad51C-Rad51D-XRCC2 complex(GO:0033063)
0.5 2.8 GO:0071986 Ragulator complex(GO:0071986)
0.5 12.5 GO:0005697 telomerase holoenzyme complex(GO:0005697)
0.5 1.4 GO:0055087 Ski complex(GO:0055087)
0.4 3.8 GO:0000347 THO complex(GO:0000347) THO complex part of transcription export complex(GO:0000445)
0.4 5.1 GO:0035748 myelin sheath abaxonal region(GO:0035748)
0.4 1.1 GO:0071001 U4/U6 snRNP(GO:0071001)
0.3 3.7 GO:0031618 nuclear pericentric heterochromatin(GO:0031618)
0.3 2.6 GO:0005785 signal recognition particle receptor complex(GO:0005785)
0.3 1.6 GO:0032777 Piccolo NuA4 histone acetyltransferase complex(GO:0032777)
0.3 0.9 GO:0005673 transcription factor TFIIE complex(GO:0005673)
0.2 2.2 GO:0030478 actin cap(GO:0030478)
0.2 2.2 GO:1990316 ATG1/ULK1 kinase complex(GO:1990316)
0.2 0.7 GO:0070557 PCNA-p21 complex(GO:0070557)
0.2 2.5 GO:0034464 BBSome(GO:0034464)
0.2 3.3 GO:0032039 integrator complex(GO:0032039)
0.2 0.8 GO:0045251 mitochondrial electron transfer flavoprotein complex(GO:0017133) electron transfer flavoprotein complex(GO:0045251)
0.2 3.1 GO:0051286 cell tip(GO:0051286)
0.2 1.1 GO:0044615 nuclear pore nuclear basket(GO:0044615)
0.2 1.7 GO:0000796 condensin complex(GO:0000796)
0.2 1.4 GO:0070652 HAUS complex(GO:0070652)
0.2 0.2 GO:0070876 SOSS complex(GO:0070876)
0.2 5.7 GO:0035371 microtubule plus-end(GO:0035371)
0.2 1.0 GO:0005687 U4 snRNP(GO:0005687)
0.2 6.0 GO:0035869 ciliary transition zone(GO:0035869)
0.2 0.9 GO:0044613 nuclear pore central transport channel(GO:0044613)
0.2 1.5 GO:0033270 paranode region of axon(GO:0033270)
0.1 1.2 GO:0000127 transcription factor TFIIIC complex(GO:0000127)
0.1 3.0 GO:0016580 Sin3 complex(GO:0016580)
0.1 3.2 GO:0035098 ESC/E(Z) complex(GO:0035098)
0.1 0.4 GO:0031933 telomeric heterochromatin(GO:0031933)
0.1 0.5 GO:0005947 mitochondrial alpha-ketoglutarate dehydrogenase complex(GO:0005947)
0.1 0.7 GO:0032389 MutLalpha complex(GO:0032389)
0.1 3.5 GO:0051233 spindle midzone(GO:0051233)
0.1 4.4 GO:0000407 pre-autophagosomal structure(GO:0000407)
0.1 0.7 GO:0005968 Rab-protein geranylgeranyltransferase complex(GO:0005968)
0.1 1.3 GO:0070938 contractile ring(GO:0070938)
0.1 2.0 GO:0042555 MCM complex(GO:0042555)
0.1 0.4 GO:0018444 translation release factor complex(GO:0018444)
0.1 9.6 GO:0016328 lateral plasma membrane(GO:0016328)
0.1 1.9 GO:0017119 Golgi transport complex(GO:0017119)
0.1 12.7 GO:0005913 cell-cell adherens junction(GO:0005913)
0.1 0.5 GO:0043259 laminin-1 complex(GO:0005606) laminin-10 complex(GO:0043259)
0.1 1.1 GO:0097165 nuclear stress granule(GO:0097165)
0.1 1.4 GO:0010369 chromocenter(GO:0010369)
0.1 1.2 GO:0061700 GATOR2 complex(GO:0061700)
0.1 3.1 GO:0005689 U12-type spliceosomal complex(GO:0005689)
0.1 0.3 GO:1990047 spindle matrix(GO:1990047)
0.1 0.8 GO:0090543 Flemming body(GO:0090543)
0.1 0.6 GO:0043220 Schmidt-Lanterman incisure(GO:0043220)
0.1 0.6 GO:0032299 ribonuclease H2 complex(GO:0032299)
0.1 0.3 GO:0035867 alphav-beta3 integrin-IGF-1-IGF1R complex(GO:0035867)
0.1 3.5 GO:0032839 dendrite cytoplasm(GO:0032839)
0.1 0.6 GO:0005956 protein kinase CK2 complex(GO:0005956)
0.1 1.3 GO:0005682 U5 snRNP(GO:0005682)
0.1 1.2 GO:0008540 proteasome regulatory particle, base subcomplex(GO:0008540)
0.1 2.6 GO:0071013 catalytic step 2 spliceosome(GO:0071013)
0.1 0.5 GO:0061689 tricellular tight junction(GO:0061689)
0.1 0.9 GO:0097542 ciliary tip(GO:0097542)
0.1 0.7 GO:0031390 Ctf18 RFC-like complex(GO:0031390)
0.1 3.4 GO:0005881 cytoplasmic microtubule(GO:0005881)
0.1 0.4 GO:0097361 CIA complex(GO:0097361)
0.1 4.0 GO:0000315 organellar large ribosomal subunit(GO:0000315) mitochondrial large ribosomal subunit(GO:0005762)
0.1 0.6 GO:0031080 nuclear pore outer ring(GO:0031080)
0.1 0.3 GO:0044611 nuclear pore inner ring(GO:0044611)
0.1 0.6 GO:0032584 growth cone membrane(GO:0032584)
0.1 6.7 GO:0000784 nuclear chromosome, telomeric region(GO:0000784)
0.1 1.7 GO:0000781 chromosome, telomeric region(GO:0000781)
0.1 5.7 GO:0030175 filopodium(GO:0030175)
0.1 0.5 GO:0005744 mitochondrial inner membrane presequence translocase complex(GO:0005744)
0.1 0.5 GO:0030057 desmosome(GO:0030057)
0.1 1.5 GO:0005680 anaphase-promoting complex(GO:0005680)
0.1 1.3 GO:0042470 melanosome(GO:0042470) pigment granule(GO:0048770)
0.1 1.2 GO:0030285 integral component of synaptic vesicle membrane(GO:0030285) intrinsic component of synaptic vesicle membrane(GO:0098563)
0.1 0.4 GO:0033256 I-kappaB/NF-kappaB complex(GO:0033256)
0.0 0.8 GO:0031616 spindle pole centrosome(GO:0031616)
0.0 0.7 GO:0031083 BLOC-1 complex(GO:0031083)
0.0 1.3 GO:0080008 Cul4-RING E3 ubiquitin ligase complex(GO:0080008)
0.0 0.3 GO:0071664 beta-catenin-TCF7L2 complex(GO:0070369) catenin-TCF7L2 complex(GO:0071664)
0.0 0.2 GO:0031523 Myb complex(GO:0031523)
0.0 0.3 GO:0097422 tubular endosome(GO:0097422)
0.0 0.3 GO:0044305 calyx of Held(GO:0044305)
0.0 0.4 GO:0005686 U2 snRNP(GO:0005686)
0.0 20.2 GO:0005813 centrosome(GO:0005813)
0.0 1.3 GO:0005871 kinesin complex(GO:0005871)
0.0 1.3 GO:0060077 inhibitory synapse(GO:0060077)
0.0 2.5 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.0 1.1 GO:0090575 RNA polymerase II transcription factor complex(GO:0090575)
0.0 2.6 GO:0005844 polysome(GO:0005844)
0.0 0.5 GO:0034663 endoplasmic reticulum chaperone complex(GO:0034663)
0.0 1.5 GO:0016592 mediator complex(GO:0016592)
0.0 0.2 GO:0035145 exon-exon junction complex(GO:0035145)
0.0 0.2 GO:0031415 NatA complex(GO:0031415)
0.0 0.2 GO:0005971 ribonucleoside-diphosphate reductase complex(GO:0005971)
0.0 0.4 GO:0044322 endoplasmic reticulum quality control compartment(GO:0044322)
0.0 0.1 GO:0033061 DNA recombinase mediator complex(GO:0033061)
0.0 0.1 GO:0005662 DNA replication factor A complex(GO:0005662)
0.0 0.1 GO:0089701 U2AF(GO:0089701)
0.0 1.3 GO:0042645 nucleoid(GO:0009295) mitochondrial nucleoid(GO:0042645)
0.0 0.7 GO:0097038 perinuclear endoplasmic reticulum(GO:0097038)
0.0 0.8 GO:0044295 axonal growth cone(GO:0044295)
0.0 0.2 GO:0097550 transcriptional preinitiation complex(GO:0097550)
0.0 3.2 GO:0030027 lamellipodium(GO:0030027)
0.0 0.3 GO:0031105 septin complex(GO:0031105)
0.0 0.7 GO:0031307 integral component of mitochondrial outer membrane(GO:0031307)
0.0 0.1 GO:0000172 ribonuclease MRP complex(GO:0000172)
0.0 0.2 GO:0033263 CORVET complex(GO:0033263)
0.0 0.1 GO:0035861 site of double-strand break(GO:0035861)
0.0 0.9 GO:0022627 cytosolic small ribosomal subunit(GO:0022627)
0.0 0.1 GO:0005771 multivesicular body(GO:0005771)
0.0 0.0 GO:0030062 mitochondrial tricarboxylic acid cycle enzyme complex(GO:0030062)
0.0 0.1 GO:0005642 annulate lamellae(GO:0005642)
0.0 0.1 GO:0098560 cytoplasmic side of late endosome membrane(GO:0098560)
0.0 0.1 GO:0048500 signal recognition particle(GO:0048500)
0.0 0.2 GO:0031528 microvillus membrane(GO:0031528)
0.0 0.6 GO:0030665 clathrin-coated vesicle membrane(GO:0030665)
0.0 0.2 GO:0030127 COPII vesicle coat(GO:0030127)
0.0 1.3 GO:0000792 heterochromatin(GO:0000792)
0.0 0.3 GO:0030131 clathrin adaptor complex(GO:0030131)
0.0 0.1 GO:0030119 AP-type membrane coat adaptor complex(GO:0030119)
0.0 0.3 GO:0005801 cis-Golgi network(GO:0005801)
0.0 0.8 GO:0005778 peroxisomal membrane(GO:0005778) microbody membrane(GO:0031903)
0.0 0.3 GO:0005669 transcription factor TFIID complex(GO:0005669)
0.0 0.1 GO:0098533 ATPase dependent transmembrane transport complex(GO:0098533)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
1.4 12.5 GO:0061676 importin-alpha family protein binding(GO:0061676)
1.2 11.7 GO:0003964 telomerase activity(GO:0003720) RNA-directed DNA polymerase activity(GO:0003964)
1.1 6.8 GO:0010997 anaphase-promoting complex binding(GO:0010997)
1.0 5.1 GO:0072542 protein phosphatase activator activity(GO:0072542)
0.8 5.0 GO:0046912 transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer(GO:0046912)
0.8 5.8 GO:0048256 flap endonuclease activity(GO:0048256)
0.8 3.2 GO:0000700 mismatch base pair DNA N-glycosylase activity(GO:0000700)
0.8 3.2 GO:1990460 leptin receptor binding(GO:1990460)
0.8 3.2 GO:0016286 small conductance calcium-activated potassium channel activity(GO:0016286)
0.7 3.6 GO:0032027 myosin light chain binding(GO:0032027)
0.7 2.0 GO:0017099 very-long-chain-acyl-CoA dehydrogenase activity(GO:0017099)
0.6 4.4 GO:0000150 recombinase activity(GO:0000150)
0.6 1.9 GO:0033829 O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase activity(GO:0033829)
0.6 3.6 GO:0046404 ATP-dependent polydeoxyribonucleotide 5'-hydroxyl-kinase activity(GO:0046404) polydeoxyribonucleotide kinase activity(GO:0051733) ATP-dependent polynucleotide kinase activity(GO:0051734)
0.6 3.6 GO:0004468 lysine N-acetyltransferase activity, acting on acetyl phosphate as donor(GO:0004468)
0.5 2.7 GO:0004809 tRNA (guanine-N2-)-methyltransferase activity(GO:0004809)
0.5 3.8 GO:0000403 Y-form DNA binding(GO:0000403)
0.5 1.6 GO:0000171 ribonuclease MRP activity(GO:0000171)
0.5 3.4 GO:0031419 cobalamin binding(GO:0031419)
0.5 2.9 GO:0003910 DNA ligase activity(GO:0003909) DNA ligase (ATP) activity(GO:0003910)
0.5 3.8 GO:0008395 steroid hydroxylase activity(GO:0008395)
0.4 2.1 GO:0035174 histone serine kinase activity(GO:0035174)
0.4 2.8 GO:0008568 microtubule-severing ATPase activity(GO:0008568)
0.4 1.2 GO:0035575 histone demethylase activity (H4-K20 specific)(GO:0035575)
0.4 3.0 GO:0030911 TPR domain binding(GO:0030911)
0.4 1.8 GO:0030621 U4 snRNA binding(GO:0030621)
0.3 2.3 GO:0004614 phosphoglucomutase activity(GO:0004614)
0.3 2.9 GO:0000774 adenyl-nucleotide exchange factor activity(GO:0000774)
0.3 1.3 GO:0035529 NADH pyrophosphatase activity(GO:0035529)
0.3 1.2 GO:0016647 oxidoreductase activity, acting on the CH-NH group of donors, oxygen as acceptor(GO:0016647)
0.3 2.8 GO:0003847 1-alkyl-2-acetylglycerophosphocholine esterase activity(GO:0003847)
0.3 4.8 GO:1904264 ubiquitin protein ligase activity involved in ERAD pathway(GO:1904264)
0.3 4.6 GO:1990226 histone methyltransferase binding(GO:1990226)
0.3 1.4 GO:0015142 citrate transmembrane transporter activity(GO:0015137) tricarboxylic acid transmembrane transporter activity(GO:0015142)
0.3 4.4 GO:0051010 microtubule plus-end binding(GO:0051010)
0.3 14.6 GO:0051019 mitogen-activated protein kinase binding(GO:0051019)
0.3 2.6 GO:0097157 pre-mRNA intronic binding(GO:0097157)
0.3 2.6 GO:0019870 potassium channel inhibitor activity(GO:0019870)
0.3 1.0 GO:0004703 G-protein coupled receptor kinase activity(GO:0004703)
0.2 2.6 GO:0016861 intramolecular oxidoreductase activity, interconverting aldoses and ketoses(GO:0016861)
0.2 1.2 GO:0004301 epoxide hydrolase activity(GO:0004301)
0.2 9.6 GO:0043027 cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027)
0.2 1.3 GO:0005047 signal recognition particle binding(GO:0005047)
0.2 1.5 GO:0061665 SUMO ligase activity(GO:0061665)
0.2 0.6 GO:0019912 cyclin-dependent protein kinase activating kinase activity(GO:0019912)
0.2 0.6 GO:0030156 benzodiazepine receptor binding(GO:0030156)
0.2 1.2 GO:0070728 leucine binding(GO:0070728)
0.2 0.8 GO:0004174 electron-transferring-flavoprotein dehydrogenase activity(GO:0004174) oxidoreductase activity, acting on the CH-NH group of donors, quinone or similar compound as acceptor(GO:0016649)
0.2 1.3 GO:0052629 phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity(GO:0052629)
0.2 1.5 GO:0009019 tRNA (guanine-N1-)-methyltransferase activity(GO:0009019)
0.2 1.0 GO:0005042 netrin receptor activity(GO:0005042)
0.2 3.2 GO:0070016 armadillo repeat domain binding(GO:0070016)
0.2 2.3 GO:0043138 3'-5' DNA helicase activity(GO:0043138)
0.2 1.2 GO:0004652 polynucleotide adenylyltransferase activity(GO:0004652)
0.2 1.4 GO:0008420 CTD phosphatase activity(GO:0008420)
0.2 0.8 GO:0005166 neurotrophin p75 receptor binding(GO:0005166)
0.2 0.6 GO:0000099 sulfur amino acid transmembrane transporter activity(GO:0000099)
0.2 3.9 GO:0098632 protein binding involved in cell-cell adhesion(GO:0098632)
0.2 1.1 GO:0015379 potassium:chloride symporter activity(GO:0015379) potassium ion symporter activity(GO:0022820)
0.1 0.4 GO:0001729 ceramide kinase activity(GO:0001729)
0.1 1.5 GO:0045236 CXCR chemokine receptor binding(GO:0045236)
0.1 8.6 GO:0003684 damaged DNA binding(GO:0003684)
0.1 1.1 GO:0016742 hydroxymethyl-, formyl- and related transferase activity(GO:0016742)
0.1 0.8 GO:0005087 Ran guanyl-nucleotide exchange factor activity(GO:0005087)
0.1 1.0 GO:0008417 fucosyltransferase activity(GO:0008417)
0.1 0.6 GO:1990715 mRNA CDS binding(GO:1990715)
0.1 0.4 GO:0070699 type II activin receptor binding(GO:0070699)
0.1 0.3 GO:0015173 aromatic amino acid transmembrane transporter activity(GO:0015173)
0.1 8.9 GO:0002039 p53 binding(GO:0002039)
0.1 1.3 GO:1990381 ubiquitin-specific protease binding(GO:1990381)
0.1 8.1 GO:0004197 cysteine-type endopeptidase activity(GO:0004197)
0.1 0.7 GO:0097001 ceramide binding(GO:0097001)
0.1 0.3 GO:0003858 3-hydroxybutyrate dehydrogenase activity(GO:0003858)
0.1 0.4 GO:0035241 protein-arginine omega-N monomethyltransferase activity(GO:0035241)
0.1 0.4 GO:0016508 long-chain-enoyl-CoA hydratase activity(GO:0016508)
0.1 1.5 GO:0008569 ATP-dependent microtubule motor activity, minus-end-directed(GO:0008569)
0.1 0.4 GO:0004045 aminoacyl-tRNA hydrolase activity(GO:0004045)
0.1 1.8 GO:0008510 sodium:bicarbonate symporter activity(GO:0008510)
0.1 1.3 GO:0031386 protein tag(GO:0031386)
0.1 4.4 GO:0017112 Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.1 3.1 GO:1990841 promoter-specific chromatin binding(GO:1990841)
0.1 1.6 GO:0016857 racemase and epimerase activity, acting on carbohydrates and derivatives(GO:0016857)
0.1 0.8 GO:0035326 enhancer binding(GO:0035326)
0.1 0.5 GO:0030144 alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase activity(GO:0030144)
0.1 0.3 GO:0001565 phorbol ester receptor activity(GO:0001565) non-kinase phorbol ester receptor activity(GO:0001566)
0.1 0.8 GO:0030274 LIM domain binding(GO:0030274)
0.1 6.4 GO:0004843 thiol-dependent ubiquitin-specific protease activity(GO:0004843)
0.1 0.5 GO:0043208 glycosphingolipid binding(GO:0043208)
0.1 0.8 GO:0030976 thiamine pyrophosphate binding(GO:0030976)
0.1 0.2 GO:0016901 glycerol-3-phosphate dehydrogenase activity(GO:0004368) oxidoreductase activity, acting on the CH-OH group of donors, quinone or similar compound as acceptor(GO:0016901)
0.1 0.5 GO:0036310 annealing helicase activity(GO:0036310)
0.1 3.0 GO:0001671 ATPase activator activity(GO:0001671)
0.1 2.1 GO:0008139 nuclear localization sequence binding(GO:0008139)
0.1 0.6 GO:0004571 mannosyl-oligosaccharide 1,2-alpha-mannosidase activity(GO:0004571)
0.1 0.4 GO:0034452 dynactin binding(GO:0034452)
0.1 0.2 GO:0000033 alpha-1,3-mannosyltransferase activity(GO:0000033)
0.1 0.4 GO:0008556 sodium:potassium-exchanging ATPase activity(GO:0005391) potassium-transporting ATPase activity(GO:0008556)
0.1 1.3 GO:0008483 transaminase activity(GO:0008483)
0.1 0.6 GO:0016004 phospholipase activator activity(GO:0016004) lipase activator activity(GO:0060229)
0.1 0.7 GO:0003689 DNA clamp loader activity(GO:0003689) protein-DNA loading ATPase activity(GO:0033170)
0.1 0.3 GO:0004849 uridine kinase activity(GO:0004849)
0.1 0.4 GO:0005138 interleukin-6 receptor binding(GO:0005138)
0.1 2.5 GO:0032452 histone demethylase activity(GO:0032452)
0.1 0.7 GO:0009922 fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338)
0.1 0.4 GO:0015277 kainate selective glutamate receptor activity(GO:0015277)
0.1 1.7 GO:0000175 3'-5'-exoribonuclease activity(GO:0000175)
0.1 1.3 GO:0017160 Ral GTPase binding(GO:0017160)
0.1 0.9 GO:0046527 glucosyltransferase activity(GO:0046527)
0.1 0.4 GO:0017134 fibroblast growth factor binding(GO:0017134)
0.1 3.1 GO:0019894 kinesin binding(GO:0019894)
0.1 0.4 GO:0042296 ISG15 transferase activity(GO:0042296)
0.1 1.0 GO:0070402 NADPH binding(GO:0070402)
0.1 0.5 GO:0035613 RNA stem-loop binding(GO:0035613)
0.1 1.3 GO:0004385 guanylate kinase activity(GO:0004385)
0.1 0.3 GO:0008269 JAK pathway signal transduction adaptor activity(GO:0008269)
0.1 0.3 GO:0008865 fructokinase activity(GO:0008865) mannokinase activity(GO:0019158)
0.1 0.6 GO:0008174 mRNA methyltransferase activity(GO:0008174)
0.1 0.4 GO:0016423 tRNA (guanine) methyltransferase activity(GO:0016423)
0.1 1.1 GO:0005487 nucleocytoplasmic transporter activity(GO:0005487)
0.0 0.6 GO:0036459 thiol-dependent ubiquitinyl hydrolase activity(GO:0036459) ubiquitinyl hydrolase activity(GO:0101005)
0.0 1.8 GO:0043015 gamma-tubulin binding(GO:0043015)
0.0 0.3 GO:0043559 insulin binding(GO:0043559)
0.0 1.9 GO:0061631 ubiquitin conjugating enzyme activity(GO:0061631)
0.0 6.7 GO:0017137 Rab GTPase binding(GO:0017137)
0.0 0.1 GO:0004711 ribosomal protein S6 kinase activity(GO:0004711)
0.0 0.1 GO:0036132 13-prostaglandin reductase activity(GO:0036132) 15-oxoprostaglandin 13-oxidase activity(GO:0047522)
0.0 0.6 GO:0008484 sulfuric ester hydrolase activity(GO:0008484)
0.0 0.1 GO:0034190 apolipoprotein receptor binding(GO:0034190)
0.0 1.4 GO:0030544 Hsp70 protein binding(GO:0030544)
0.0 0.4 GO:0070181 small ribosomal subunit rRNA binding(GO:0070181)
0.0 0.5 GO:0017056 structural constituent of nuclear pore(GO:0017056)
0.0 0.9 GO:0004697 protein kinase C activity(GO:0004697)
0.0 0.2 GO:0004719 protein-L-isoaspartate (D-aspartate) O-methyltransferase activity(GO:0004719)
0.0 0.3 GO:0003747 translation release factor activity(GO:0003747) translation termination factor activity(GO:0008079)
0.0 0.3 GO:1990247 N6-methyladenosine-containing RNA binding(GO:1990247)
0.0 0.2 GO:0008479 queuine tRNA-ribosyltransferase activity(GO:0008479)
0.0 0.1 GO:0032767 copper-dependent protein binding(GO:0032767)
0.0 0.4 GO:0008474 palmitoyl-(protein) hydrolase activity(GO:0008474) palmitoyl hydrolase activity(GO:0098599)
0.0 3.3 GO:0015171 amino acid transmembrane transporter activity(GO:0015171)
0.0 0.2 GO:0003839 gamma-glutamylcyclotransferase activity(GO:0003839)
0.0 0.1 GO:0030942 endoplasmic reticulum signal peptide binding(GO:0030942)
0.0 0.6 GO:0008353 RNA polymerase II carboxy-terminal domain kinase activity(GO:0008353)
0.0 1.7 GO:0051087 chaperone binding(GO:0051087)
0.0 0.4 GO:0030296 protein tyrosine kinase activator activity(GO:0030296)
0.0 0.2 GO:0019961 interferon binding(GO:0019961)
0.0 0.7 GO:0004708 MAP kinase kinase activity(GO:0004708)
0.0 1.9 GO:0035064 methylated histone binding(GO:0035064)
0.0 0.2 GO:0061731 ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor(GO:0004748) oxidoreductase activity, acting on CH or CH2 groups, disulfide as acceptor(GO:0016728) ribonucleoside-diphosphate reductase activity(GO:0061731)
0.0 0.1 GO:0000995 transcription factor activity, core RNA polymerase III binding(GO:0000995)
0.0 0.1 GO:0016262 protein N-acetylglucosaminyltransferase activity(GO:0016262)
0.0 3.4 GO:0005089 Rho guanyl-nucleotide exchange factor activity(GO:0005089)
0.0 1.7 GO:0003777 microtubule motor activity(GO:0003777)
0.0 0.1 GO:0052658 inositol-1,4,5-trisphosphate 5-phosphatase activity(GO:0052658)
0.0 0.5 GO:0004029 aldehyde dehydrogenase (NAD) activity(GO:0004029)
0.0 0.9 GO:0046966 thyroid hormone receptor binding(GO:0046966)
0.0 0.5 GO:0042800 histone methyltransferase activity (H3-K4 specific)(GO:0042800)
0.0 0.5 GO:0003950 NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.0 0.2 GO:0042162 telomeric DNA binding(GO:0042162)
0.0 0.1 GO:0016971 flavin-linked sulfhydryl oxidase activity(GO:0016971)
0.0 0.2 GO:0033743 peptide-methionine (R)-S-oxide reductase activity(GO:0033743)
0.0 1.5 GO:0004722 protein serine/threonine phosphatase activity(GO:0004722)
0.0 0.4 GO:0005247 voltage-gated chloride channel activity(GO:0005247)
0.0 0.3 GO:0004185 serine-type carboxypeptidase activity(GO:0004185)
0.0 0.1 GO:0031752 D5 dopamine receptor binding(GO:0031752)
0.0 0.1 GO:0044547 DNA topoisomerase binding(GO:0044547)
0.0 1.1 GO:0000977 RNA polymerase II regulatory region sequence-specific DNA binding(GO:0000977)
0.0 0.1 GO:0008061 chitin binding(GO:0008061)
0.0 0.3 GO:0048531 beta-1,3-galactosyltransferase activity(GO:0048531)
0.0 0.1 GO:0008297 single-stranded DNA exodeoxyribonuclease activity(GO:0008297)
0.0 3.2 GO:0004386 helicase activity(GO:0004386)
0.0 0.2 GO:1990825 sequence-specific mRNA binding(GO:1990825)
0.0 2.0 GO:0003682 chromatin binding(GO:0003682)
0.0 0.1 GO:0008494 translation activator activity(GO:0008494)
0.0 3.9 GO:0003735 structural constituent of ribosome(GO:0003735)
0.0 0.5 GO:0008157 protein phosphatase 1 binding(GO:0008157)
0.0 3.3 GO:0017124 SH3 domain binding(GO:0017124)
0.0 0.5 GO:0051539 4 iron, 4 sulfur cluster binding(GO:0051539)
0.0 0.2 GO:0071837 HMG box domain binding(GO:0071837)
0.0 0.1 GO:0000268 peroxisome targeting sequence binding(GO:0000268)
0.0 0.7 GO:0008080 N-acetyltransferase activity(GO:0008080)
0.0 0.5 GO:0004712 protein serine/threonine/tyrosine kinase activity(GO:0004712)
0.0 0.3 GO:0003995 acyl-CoA dehydrogenase activity(GO:0003995)
0.0 0.2 GO:0019215 intermediate filament binding(GO:0019215)
0.0 0.2 GO:0031210 phosphatidylcholine binding(GO:0031210)
0.0 1.2 GO:0003730 mRNA 3'-UTR binding(GO:0003730)
0.0 0.2 GO:0042975 peroxisome proliferator activated receptor binding(GO:0042975)
0.0 1.2 GO:0004553 hydrolase activity, hydrolyzing O-glycosyl compounds(GO:0004553)
0.0 0.1 GO:0005522 profilin binding(GO:0005522)
0.0 0.1 GO:0004092 carnitine O-acetyltransferase activity(GO:0004092)
0.0 0.5 GO:0004715 non-membrane spanning protein tyrosine kinase activity(GO:0004715)
0.0 0.3 GO:0102391 decanoate--CoA ligase activity(GO:0102391)
0.0 0.3 GO:0000062 fatty-acyl-CoA binding(GO:0000062)
0.0 0.2 GO:0003899 DNA-directed RNA polymerase activity(GO:0003899) RNA polymerase activity(GO:0034062)
0.0 0.5 GO:0001106 RNA polymerase II transcription corepressor activity(GO:0001106)
0.0 0.5 GO:0017025 TBP-class protein binding(GO:0017025)
0.0 0.1 GO:0070990 snRNP binding(GO:0070990)
0.0 0.1 GO:0022841 potassium ion leak channel activity(GO:0022841)
0.0 0.3 GO:0017091 AU-rich element binding(GO:0017091)
0.0 1.2 GO:0033613 activating transcription factor binding(GO:0033613)
0.0 1.4 GO:0070851 growth factor receptor binding(GO:0070851)
0.0 0.2 GO:0004596 peptide alpha-N-acetyltransferase activity(GO:0004596)
0.0 0.1 GO:0004382 guanosine-diphosphatase activity(GO:0004382)
0.0 0.1 GO:0030628 pre-mRNA 3'-splice site binding(GO:0030628)
0.0 0.4 GO:0005112 Notch binding(GO:0005112)
0.0 0.5 GO:0003755 peptidyl-prolyl cis-trans isomerase activity(GO:0003755)
0.0 0.3 GO:0034061 DNA polymerase activity(GO:0034061)
0.0 0.1 GO:0003917 DNA topoisomerase type I activity(GO:0003917)
0.0 0.8 GO:0003697 single-stranded DNA binding(GO:0003697)
0.0 2.3 GO:0005516 calmodulin binding(GO:0005516)
0.0 0.9 GO:0003713 transcription coactivator activity(GO:0003713)
0.0 0.0 GO:0004774 succinate-CoA ligase activity(GO:0004774)
0.0 0.1 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.0 0.4 GO:0005160 transforming growth factor beta receptor binding(GO:0005160)
0.0 0.2 GO:0018024 histone-lysine N-methyltransferase activity(GO:0018024)
0.0 0.1 GO:0017169 CDP-alcohol phosphatidyltransferase activity(GO:0017169)
0.0 0.1 GO:0001206 transcriptional repressor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001206)
0.0 0.3 GO:0001103 RNA polymerase II repressing transcription factor binding(GO:0001103)
0.0 0.2 GO:0051879 Hsp90 protein binding(GO:0051879)
0.0 2.9 GO:0001077 transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001077)
0.0 0.3 GO:0008376 acetylgalactosaminyltransferase activity(GO:0008376)
0.0 0.1 GO:0001223 transcription coactivator binding(GO:0001223)
0.0 0.3 GO:0031492 nucleosomal DNA binding(GO:0031492)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
1.0 42.3 PID_AURORA_A_PATHWAY Aurora A signaling
0.3 12.0 PID_AURORA_B_PATHWAY Aurora B signaling
0.3 2.3 SA_G2_AND_M_PHASES Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
0.2 11.8 PID_PLK1_PATHWAY PLK1 signaling events
0.2 4.7 PID_MYC_PATHWAY C-MYC pathway
0.2 5.8 PID_ATR_PATHWAY ATR signaling pathway
0.1 2.4 PID_FRA_PATHWAY Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.1 0.5 PID_NEPHRIN_NEPH1_PATHWAY Nephrin/Neph1 signaling in the kidney podocyte
0.1 0.5 PID_INTEGRIN4_PATHWAY Alpha6 beta4 integrin-ligand interactions
0.1 5.3 PID_SMAD2_3NUCLEAR_PATHWAY Regulation of nuclear SMAD2/3 signaling
0.1 1.8 PID_DELTA_NP63_PATHWAY Validated transcriptional targets of deltaNp63 isoforms
0.0 1.5 PID_ERBB1_RECEPTOR_PROXIMAL_PATHWAY EGF receptor (ErbB1) signaling pathway
0.0 0.8 PID_P38_GAMMA_DELTA_PATHWAY Signaling mediated by p38-gamma and p38-delta
0.0 1.0 PID_SMAD2_3PATHWAY Regulation of cytoplasmic and nuclear SMAD2/3 signaling
0.0 3.0 PID_AJDISS_2PATHWAY Posttranslational regulation of adherens junction stability and dissassembly
0.0 1.5 PID_ECADHERIN_NASCENT_AJ_PATHWAY E-cadherin signaling in the nascent adherens junction
0.0 3.1 PID_CDC42_PATHWAY CDC42 signaling events
0.0 1.3 PID_ALPHA_SYNUCLEIN_PATHWAY Alpha-synuclein signaling
0.0 1.8 PID_NETRIN_PATHWAY Netrin-mediated signaling events
0.0 1.5 PID_HNF3B_PATHWAY FOXA2 and FOXA3 transcription factor networks
0.0 1.3 PID_ECADHERIN_STABILIZATION_PATHWAY Stabilization and expansion of the E-cadherin adherens junction
0.0 0.2 PID_SYNDECAN_1_PATHWAY Syndecan-1-mediated signaling events
0.0 1.1 PID_ARF6_PATHWAY Arf6 signaling events
0.0 0.1 PID_SYNDECAN_4_PATHWAY Syndecan-4-mediated signaling events
0.0 1.6 PID_ERA_GENOMIC_PATHWAY Validated nuclear estrogen receptor alpha network
0.0 1.6 PID_TELOMERASE_PATHWAY Regulation of Telomerase
0.0 0.5 PID_IL2_1PATHWAY IL2-mediated signaling events
0.0 0.7 PID_HEDGEHOG_2PATHWAY Signaling events mediated by the Hedgehog family
0.0 0.7 PID_ATM_PATHWAY ATM pathway
0.0 0.7 PID_IL6_7_PATHWAY IL6-mediated signaling events
0.0 0.8 PID_IL4_2PATHWAY IL4-mediated signaling events
0.0 0.6 PID_CDC42_REG_PATHWAY Regulation of CDC42 activity
0.0 0.4 PID_TRKR_PATHWAY Neurotrophic factor-mediated Trk receptor signaling
0.0 0.2 PID_UPA_UPAR_PATHWAY Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling
0.0 0.8 PID_RHOA_REG_PATHWAY Regulation of RhoA activity
0.0 0.5 PID_TGFBR_PATHWAY TGF-beta receptor signaling
0.0 0.5 PID_RB_1PATHWAY Regulation of retinoblastoma protein
0.0 0.6 PID_TNF_PATHWAY TNF receptor signaling pathway
0.0 0.1 SA_B_CELL_RECEPTOR_COMPLEXES Antigen binding to B cell receptors activates protein tyrosine kinases, such as the Src family, which ultimate activate MAP kinases.
0.0 1.4 NABA_ECM_GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.0 0.3 PID_AP1_PATHWAY AP-1 transcription factor network
0.0 0.7 PID_MYC_ACTIV_PATHWAY Validated targets of C-MYC transcriptional activation

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
1.2 1.2 REACTOME_E2F_ENABLED_INHIBITION_OF_PRE_REPLICATION_COMPLEX_FORMATION Genes involved in E2F-enabled inhibition of pre-replication complex formation
0.7 12.2 REACTOME_HOMOLOGOUS_RECOMBINATION_REPAIR_OF_REPLICATION_INDEPENDENT_DOUBLE_STRAND_BREAKS Genes involved in Homologous recombination repair of replication-independent double-strand breaks
0.5 3.8 REACTOME_ENDOGENOUS_STEROLS Genes involved in Endogenous sterols
0.4 3.0 REACTOME_REMOVAL_OF_THE_FLAP_INTERMEDIATE_FROM_THE_C_STRAND Genes involved in Removal of the Flap Intermediate from the C-strand
0.4 8.9 REACTOME_INHIBITION_OF_THE_PROTEOLYTIC_ACTIVITY_OF_APC_C_REQUIRED_FOR_THE_ONSET_OF_ANAPHASE_BY_MITOTIC_SPINDLE_CHECKPOINT_COMPONENTS Genes involved in Inhibition of the proteolytic activity of APC/C required for the onset of anaphase by mitotic spindle checkpoint components
0.3 35.3 REACTOME_MITOTIC_PROMETAPHASE Genes involved in Mitotic Prometaphase
0.3 4.9 REACTOME_UNWINDING_OF_DNA Genes involved in Unwinding of DNA
0.3 2.2 REACTOME_G2_M_DNA_DAMAGE_CHECKPOINT Genes involved in G2/M DNA damage checkpoint
0.3 4.5 REACTOME_PROCESSING_OF_INTRONLESS_PRE_MRNAS Genes involved in Processing of Intronless Pre-mRNAs
0.2 2.4 REACTOME_CDC6_ASSOCIATION_WITH_THE_ORC_ORIGIN_COMPLEX Genes involved in CDC6 association with the ORC:origin complex
0.2 3.0 REACTOME_ACTIVATION_OF_IRF3_IRF7_MEDIATED_BY_TBK1_IKK_EPSILON Genes involved in Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon
0.2 6.4 REACTOME_TIGHT_JUNCTION_INTERACTIONS Genes involved in Tight junction interactions
0.2 6.0 REACTOME_FATTY_ACYL_COA_BIOSYNTHESIS Genes involved in Fatty Acyl-CoA Biosynthesis
0.2 1.9 REACTOME_BASE_FREE_SUGAR_PHOSPHATE_REMOVAL_VIA_THE_SINGLE_NUCLEOTIDE_REPLACEMENT_PATHWAY Genes involved in Base-free sugar-phosphate removal via the single-nucleotide replacement pathway
0.1 2.1 REACTOME_NEGATIVE_REGULATION_OF_THE_PI3K_AKT_NETWORK Genes involved in Negative regulation of the PI3K/AKT network
0.1 1.9 REACTOME_HYALURONAN_METABOLISM Genes involved in Hyaluronan metabolism
0.1 4.7 REACTOME_SMAD2_SMAD3_SMAD4_HETEROTRIMER_REGULATES_TRANSCRIPTION Genes involved in SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription
0.1 2.4 REACTOME_NEP_NS2_INTERACTS_WITH_THE_CELLULAR_EXPORT_MACHINERY Genes involved in NEP/NS2 Interacts with the Cellular Export Machinery
0.1 1.1 REACTOME_RECEPTOR_LIGAND_BINDING_INITIATES_THE_SECOND_PROTEOLYTIC_CLEAVAGE_OF_NOTCH_RECEPTOR Genes involved in Receptor-ligand binding initiates the second proteolytic cleavage of Notch receptor
0.1 1.3 REACTOME_SYNTHESIS_OF_PIPS_AT_THE_EARLY_ENDOSOME_MEMBRANE Genes involved in Synthesis of PIPs at the early endosome membrane
0.1 6.0 REACTOME_GOLGI_ASSOCIATED_VESICLE_BIOGENESIS Genes involved in Golgi Associated Vesicle Biogenesis
0.1 1.5 REACTOME_MITOCHONDRIAL_FATTY_ACID_BETA_OXIDATION Genes involved in Mitochondrial Fatty Acid Beta-Oxidation
0.1 0.6 REACTOME_TRAFFICKING_AND_PROCESSING_OF_ENDOSOMAL_TLR Genes involved in Trafficking and processing of endosomal TLR
0.1 1.0 REACTOME_ROLE_OF_DCC_IN_REGULATING_APOPTOSIS Genes involved in Role of DCC in regulating apoptosis
0.1 0.6 REACTOME_THE_ACTIVATION_OF_ARYLSULFATASES Genes involved in The activation of arylsulfatases
0.1 0.8 REACTOME_SIGNAL_TRANSDUCTION_BY_L1 Genes involved in Signal transduction by L1
0.1 2.3 REACTOME_G1_PHASE Genes involved in G1 Phase
0.1 2.8 REACTOME_RNA_POL_III_TRANSCRIPTION Genes involved in RNA Polymerase III Transcription
0.1 0.9 REACTOME_IRAK1_RECRUITS_IKK_COMPLEX Genes involved in IRAK1 recruits IKK complex
0.1 1.3 REACTOME_ABORTIVE_ELONGATION_OF_HIV1_TRANSCRIPT_IN_THE_ABSENCE_OF_TAT Genes involved in Abortive elongation of HIV-1 transcript in the absence of Tat
0.1 0.8 REACTOME_P130CAS_LINKAGE_TO_MAPK_SIGNALING_FOR_INTEGRINS Genes involved in p130Cas linkage to MAPK signaling for integrins
0.1 1.5 REACTOME_MRNA_3_END_PROCESSING Genes involved in mRNA 3'-end processing
0.1 0.6 REACTOME_CALNEXIN_CALRETICULIN_CYCLE Genes involved in Calnexin/calreticulin cycle
0.1 1.7 REACTOME_PEROXISOMAL_LIPID_METABOLISM Genes involved in Peroxisomal lipid metabolism
0.0 1.1 REACTOME_CASPASE_MEDIATED_CLEAVAGE_OF_CYTOSKELETAL_PROTEINS Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.0 0.7 REACTOME_ACTIVATED_TAK1_MEDIATES_P38_MAPK_ACTIVATION Genes involved in activated TAK1 mediates p38 MAPK activation
0.0 1.0 REACTOME_KINESINS Genes involved in Kinesins
0.0 0.9 REACTOME_INSULIN_SYNTHESIS_AND_PROCESSING Genes involved in Insulin Synthesis and Processing
0.0 1.4 REACTOME_ANTIVIRAL_MECHANISM_BY_IFN_STIMULATED_GENES Genes involved in Antiviral mechanism by IFN-stimulated genes
0.0 1.0 REACTOME_DEADENYLATION_OF_MRNA Genes involved in Deadenylation of mRNA
0.0 0.9 REACTOME_RNA_POL_II_TRANSCRIPTION_PRE_INITIATION_AND_PROMOTER_OPENING Genes involved in RNA Polymerase II Transcription Pre-Initiation And Promoter Opening
0.0 0.2 REACTOME_P53_DEPENDENT_G1_DNA_DAMAGE_RESPONSE Genes involved in p53-Dependent G1 DNA Damage Response
0.0 0.2 REACTOME_APOPTOTIC_CLEAVAGE_OF_CELL_ADHESION_PROTEINS Genes involved in Apoptotic cleavage of cell adhesion proteins
0.0 0.8 REACTOME_MRNA_SPLICING_MINOR_PATHWAY Genes involved in mRNA Splicing - Minor Pathway
0.0 3.0 REACTOME_TRANSPORT_OF_INORGANIC_CATIONS_ANIONS_AND_AMINO_ACIDS_OLIGOPEPTIDES Genes involved in Transport of inorganic cations/anions and amino acids/oligopeptides
0.0 0.3 REACTOME_GLUTAMATE_NEUROTRANSMITTER_RELEASE_CYCLE Genes involved in Glutamate Neurotransmitter Release Cycle
0.0 0.7 REACTOME_SIGNALING_BY_CONSTITUTIVELY_ACTIVE_EGFR Genes involved in Signaling by constitutively active EGFR
0.0 1.6 REACTOME_ER_PHAGOSOME_PATHWAY Genes involved in ER-Phagosome pathway
0.0 0.7 REACTOME_AMINO_ACID_SYNTHESIS_AND_INTERCONVERSION_TRANSAMINATION Genes involved in Amino acid synthesis and interconversion (transamination)
0.0 0.4 REACTOME_DOWNREGULATION_OF_TGF_BETA_RECEPTOR_SIGNALING Genes involved in Downregulation of TGF-beta receptor signaling
0.0 0.2 REACTOME_CD28_DEPENDENT_VAV1_PATHWAY Genes involved in CD28 dependent Vav1 pathway
0.0 0.3 REACTOME_GLUCOSE_TRANSPORT Genes involved in Glucose transport
0.0 0.7 REACTOME_MYOGENESIS Genes involved in Myogenesis
0.0 0.1 REACTOME_TRYPTOPHAN_CATABOLISM Genes involved in Tryptophan catabolism
0.0 0.4 REACTOME_IONOTROPIC_ACTIVITY_OF_KAINATE_RECEPTORS Genes involved in Ionotropic activity of Kainate Receptors
0.0 0.4 REACTOME_METABOLISM_OF_PORPHYRINS Genes involved in Metabolism of porphyrins
0.0 0.1 REACTOME_REGULATION_OF_ORNITHINE_DECARBOXYLASE_ODC Genes involved in Regulation of ornithine decarboxylase (ODC)
0.0 0.3 REACTOME_EGFR_DOWNREGULATION Genes involved in EGFR downregulation
0.0 0.1 REACTOME_NFKB_IS_ACTIVATED_AND_SIGNALS_SURVIVAL Genes involved in NF-kB is activated and signals survival
0.0 0.4 REACTOME_SULFUR_AMINO_ACID_METABOLISM Genes involved in Sulfur amino acid metabolism
0.0 0.3 REACTOME_BASIGIN_INTERACTIONS Genes involved in Basigin interactions
0.0 0.2 REACTOME_CHYLOMICRON_MEDIATED_LIPID_TRANSPORT Genes involved in Chylomicron-mediated lipid transport
0.0 0.4 REACTOME_INTERACTION_BETWEEN_L1_AND_ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.0 0.4 REACTOME_SMOOTH_MUSCLE_CONTRACTION Genes involved in Smooth Muscle Contraction
0.0 0.3 REACTOME_REGULATION_OF_BETA_CELL_DEVELOPMENT Genes involved in Regulation of beta-cell development
0.0 0.3 REACTOME_CELL_EXTRACELLULAR_MATRIX_INTERACTIONS Genes involved in Cell-extracellular matrix interactions
0.0 0.2 REACTOME_BRANCHED_CHAIN_AMINO_ACID_CATABOLISM Genes involved in Branched-chain amino acid catabolism
0.0 0.1 REACTOME_ANTIGEN_PRESENTATION_FOLDING_ASSEMBLY_AND_PEPTIDE_LOADING_OF_CLASS_I_MHC Genes involved in Antigen Presentation: Folding, assembly and peptide loading of class I MHC
0.0 0.5 REACTOME_INTEGRIN_CELL_SURFACE_INTERACTIONS Genes involved in Integrin cell surface interactions
0.0 0.2 REACTOME_NEGATIVE_REGULATORS_OF_RIG_I_MDA5_SIGNALING Genes involved in Negative regulators of RIG-I/MDA5 signaling