Motif ID: Hdx

Z-value: 5.229


Transcription factors associated with Hdx:

Gene SymbolEntrez IDGene Name
Hdx ENSMUSG00000034551.6 Hdx

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Hdxmm10_v2_chrX_-_111697069_1116971270.173.1e-01Click!


Activity profile for motif Hdx.

activity profile for motif Hdx


Sorted Z-values histogram for motif Hdx

Sorted Z-values for motif Hdx



Network of associatons between targets according to the STRING database.



First level regulatory network of Hdx

PNG image of the network

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Top targets:


Showing 1 to 20 of 68 entries
PromoterScoreRefseqGene SymbolGene Name
chr9_+_3017408 200.686 ENSMUST00000099049.3
 Gm10719
predicted gene 10719
chr9_+_3015654 165.184 ENSMUST00000099050.3
 Gm10720
predicted gene 10720
chr9_+_3023547 163.885 ENSMUST00000099046.3
 Gm10718
predicted gene 10718
chr9_+_3000922 143.191 ENSMUST00000151376.2
 Gm10722
predicted gene 10722
chr9_+_3027439 139.924 ENSMUST00000177875.1
ENSMUST00000179982.1
 Gm10717

predicted gene 10717

chr9_+_3005125 134.782 ENSMUST00000179881.1
 Gm11168
predicted gene 11168
chr9_+_3034599 128.668 ENSMUST00000178641.1
 Gm17535
predicted gene, 17535
chr9_+_3025417 115.427 ENSMUST00000075573.6
 Gm10717
predicted gene 10717
chr14_-_19418930 108.223 ENSMUST00000177817.1
 Gm21738
predicted gene, 21738
chr9_+_3018753 89.337 ENSMUST00000179272.1
 Gm10719
predicted gene 10719
chr9_+_3036877 84.481 ENSMUST00000155807.2
 Gm10715
predicted gene 10715
chr9_+_3004457 82.739 ENSMUST00000178348.1
 Gm11168
predicted gene 11168
chr9_+_3037111 79.736 ENSMUST00000177969.1
 Gm10715
predicted gene 10715
chr9_+_3013140 78.264 ENSMUST00000143083.2
 Gm10721
predicted gene 10721
chr2_-_98667264 61.214 ENSMUST00000099683.1
 Gm10800
predicted gene 10800
chr6_-_149101506 2.528 ENSMUST00000127727.1
 Dennd5b
DENN/MADD domain containing 5B
chr4_-_149126688 2.504 ENSMUST00000030815.2
 Cort
cortistatin
chr7_+_13398115 2.272 ENSMUST00000005791.7
 Cabp5
calcium binding protein 5
chr16_-_50432340 2.269 ENSMUST00000066037.6
ENSMUST00000089399.4
ENSMUST00000089404.3
ENSMUST00000114477.1
ENSMUST00000138166.1
 Bbx




bobby sox homolog (Drosophila)




chr7_+_19359740 2.223 ENSMUST00000140836.1
 Ppp1r13l
protein phosphatase 1, regulatory (inhibitor) subunit 13 like

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 12 of 12 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 1286.4 GO:0008150 biological_process(GO:0008150)
0.1 2.2 GO:0003215 cardiac right ventricle morphogenesis(GO:0003215)
0.6 1.7 GO:0050883 regulation of sulfur amino acid metabolic process(GO:0031335) musculoskeletal movement, spinal reflex action(GO:0050883)
0.4 1.7 GO:0003365 establishment of cell polarity involved in ameboidal cell migration(GO:0003365)
0.2 1.6 GO:0060164 regulation of timing of neuron differentiation(GO:0060164)
0.1 1.3 GO:0018230 peptidyl-L-cysteine S-palmitoylation(GO:0018230) peptidyl-S-diacylglycerol-L-cysteine biosynthetic process from peptidyl-cysteine(GO:0018231)
0.1 1.2 GO:0045187 regulation of circadian sleep/wake cycle, sleep(GO:0045187)
0.1 1.2 GO:0010818 T cell chemotaxis(GO:0010818)
0.1 0.6 GO:0021797 forebrain anterior/posterior pattern specification(GO:0021797)
0.2 0.5 GO:0060489 orthogonal dichotomous subdivision of terminal units involved in lung branching morphogenesis(GO:0060488) planar dichotomous subdivision of terminal units involved in lung branching morphogenesis(GO:0060489) lateral sprouting involved in lung morphogenesis(GO:0060490)
0.1 0.4 GO:0046381 CMP-N-acetylneuraminate metabolic process(GO:0046381)
0.1 0.4 GO:0021905 pancreatic A cell development(GO:0003322) forebrain-midbrain boundary formation(GO:0021905) somatic motor neuron fate commitment(GO:0021917) regulation of transcription from RNA polymerase II promoter involved in somatic motor neuron fate commitment(GO:0021918) sensory neuron migration(GO:1904937)

Gene overrepresentation in cellular_component category:

Showing 1 to 2 of 2 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 1285.6 GO:0005575 cellular_component(GO:0005575)
0.1 0.5 GO:0060187 cell pole(GO:0060187)

Gene overrepresentation in molecular_function category:

Showing 1 to 7 of 7 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 1297.0 GO:0003674 molecular_function(GO:0003674)
0.2 1.9 GO:0005068 transmembrane receptor protein tyrosine kinase adaptor activity(GO:0005068)
0.3 1.7 GO:0043532 angiostatin binding(GO:0043532)
0.1 1.7 GO:0008331 high voltage-gated calcium channel activity(GO:0008331)
0.2 1.2 GO:0048248 CXCR3 chemokine receptor binding(GO:0048248)
0.1 0.4 GO:0016716 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, another compound as one donor, and incorporation of one atom of oxygen(GO:0016716)
0.1 0.4 GO:0070330 aromatase activity(GO:0070330)

Gene overrepresentation in C2:CP category:

Showing 1 to 2 of 2 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 2.2 PID_P53_REGULATION_PATHWAY p53 pathway
0.0 1.9 PID_IL4_2PATHWAY IL4-mediated signaling events

Gene overrepresentation in C2:CP:REACTOME category:

Showing 1 to 6 of 6 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 1.7 REACTOME_SIGNALING_BY_HIPPO Genes involved in Signaling by Hippo
0.0 1.3 REACTOME_ENOS_ACTIVATION_AND_REGULATION Genes involved in eNOS activation and regulation
0.1 1.2 REACTOME_HS_GAG_DEGRADATION Genes involved in HS-GAG degradation
0.0 0.4 REACTOME_SYNTHESIS_SECRETION_AND_INACTIVATION_OF_GIP Genes involved in Synthesis, Secretion, and Inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)
0.0 0.4 REACTOME_OTHER_SEMAPHORIN_INTERACTIONS Genes involved in Other semaphorin interactions
0.0 0.3 REACTOME_SYNTHESIS_OF_GLYCOSYLPHOSPHATIDYLINOSITOL_GPI Genes involved in Synthesis of glycosylphosphatidylinositol (GPI)