Motif ID: Hic1

Z-value: 1.310


Transcription factors associated with Hic1:

Gene SymbolEntrez IDGene Name
Hic1 ENSMUSG00000043099.4 Hic1



Activity profile for motif Hic1.

activity profile for motif Hic1


Sorted Z-values histogram for motif Hic1

Sorted Z-values for motif Hic1



Network of associatons between targets according to the STRING database.



First level regulatory network of Hic1

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr8_-_84800024 7.413 ENSMUST00000126806.1
ENSMUST00000076715.6
Nfix

nuclear factor I/X

chr5_-_146585239 5.529 ENSMUST00000036211.6
Gpr12
G-protein coupled receptor 12
chr11_+_7063423 5.141 ENSMUST00000020706.4
Adcy1
adenylate cyclase 1
chr8_-_84800344 5.025 ENSMUST00000099070.3
Nfix
nuclear factor I/X
chr13_+_109903089 4.864 ENSMUST00000120664.1
Pde4d
phosphodiesterase 4D, cAMP specific
chr5_+_141241490 4.766 ENSMUST00000085774.4
Sdk1
sidekick homolog 1 (chicken)
chr8_+_70493156 4.642 ENSMUST00000008032.7
Crlf1
cytokine receptor-like factor 1
chr11_-_6065538 4.559 ENSMUST00000101585.3
ENSMUST00000066431.7
ENSMUST00000109815.2
ENSMUST00000109812.2
ENSMUST00000101586.2
ENSMUST00000093355.5
ENSMUST00000019133.4
Camk2b






calcium/calmodulin-dependent protein kinase II, beta






chr12_+_105336922 4.381 ENSMUST00000180503.1
2810011L19Rik
RIKEN cDNA 2810011L19 gene
chr18_-_58209926 4.237 ENSMUST00000025497.6
Fbn2
fibrillin 2
chr8_-_36249292 3.819 ENSMUST00000065297.5
Lonrf1
LON peptidase N-terminal domain and ring finger 1
chr4_+_141368116 3.818 ENSMUST00000006380.4
Fam131c
family with sequence similarity 131, member C
chr4_-_46991842 3.753 ENSMUST00000107749.2
Gabbr2
gamma-aminobutyric acid (GABA) B receptor, 2
chr6_-_148444336 3.734 ENSMUST00000060095.8
ENSMUST00000100772.3
Tmtc1

transmembrane and tetratricopeptide repeat containing 1

chr14_-_102982630 3.719 ENSMUST00000184744.1
KCTD12
mmu-mir-5130
chr6_+_22875496 3.611 ENSMUST00000090568.3
Ptprz1
protein tyrosine phosphatase, receptor type Z, polypeptide 1
chr17_-_83631892 3.539 ENSMUST00000051482.1
Kcng3
potassium voltage-gated channel, subfamily G, member 3
chr9_-_29412204 3.439 ENSMUST00000115237.1
Ntm
neurotrimin
chr4_-_139092958 3.393 ENSMUST00000042844.6
Nbl1
neuroblastoma, suppression of tumorigenicity 1
chr5_+_37047464 3.369 ENSMUST00000137019.1
Jakmip1
janus kinase and microtubule interacting protein 1
chr7_+_117380937 3.345 ENSMUST00000032892.5
Xylt1
xylosyltransferase 1
chr14_-_30353468 3.336 ENSMUST00000112249.1
Cacna1d
calcium channel, voltage-dependent, L type, alpha 1D subunit
chr9_-_98032983 3.332 ENSMUST00000162295.1
Clstn2
calsyntenin 2
chr6_+_17463749 3.321 ENSMUST00000115443.1
Met
met proto-oncogene
chr10_-_43174521 3.278 ENSMUST00000040275.7
Sobp
sine oculis-binding protein homolog (Drosophila)
chr2_-_157079212 3.265 ENSMUST00000069098.6
Soga1
suppressor of glucose, autophagy associated 1
chr1_-_33907721 3.260 ENSMUST00000115161.1
ENSMUST00000062289.8
Bend6

BEN domain containing 6

chr12_+_73997749 3.228 ENSMUST00000110451.2
Syt16
synaptotagmin XVI
chr10_+_79716588 3.209 ENSMUST00000099513.1
ENSMUST00000020581.2
Hcn2

hyperpolarization-activated, cyclic nucleotide-gated K+ 2

chr6_-_32588192 3.189 ENSMUST00000115096.2
Plxna4
plexin A4
chr11_-_66525964 3.163 ENSMUST00000066679.6
Shisa6
shisa homolog 6 (Xenopus laevis)
chr6_+_17463927 3.090 ENSMUST00000115442.1
Met
met proto-oncogene
chr9_+_26733845 3.089 ENSMUST00000115269.2
B3gat1
beta-1,3-glucuronyltransferase 1 (glucuronosyltransferase P)
chr6_+_65671590 3.073 ENSMUST00000054351.4
Ndnf
neuron-derived neurotrophic factor
chr13_+_117602439 3.056 ENSMUST00000006991.7
Hcn1
hyperpolarization-activated, cyclic nucleotide-gated K+ 1
chr2_-_104410334 3.046 ENSMUST00000089726.3
D430041D05Rik
RIKEN cDNA D430041D05 gene
chr18_+_67933257 3.024 ENSMUST00000063775.3
Ldlrad4
low density lipoprotein receptor class A domain containing 4
chr3_-_148989316 3.013 ENSMUST00000098518.2
Lphn2
latrophilin 2
chr9_+_60712989 3.004 ENSMUST00000038407.5
Larp6
La ribonucleoprotein domain family, member 6
chr4_-_151861667 2.994 ENSMUST00000169423.2
Camta1
calmodulin binding transcription activator 1
chr1_-_3671498 2.990 ENSMUST00000070533.4
Xkr4
X Kell blood group precursor related family member 4
chr19_-_57314896 2.962 ENSMUST00000111524.1
Ablim1
actin-binding LIM protein 1
chr14_+_119138415 2.914 ENSMUST00000065904.3
Hs6st3
heparan sulfate 6-O-sulfotransferase 3
chr6_+_17463826 2.911 ENSMUST00000140070.1
Met
met proto-oncogene
chr12_+_95695350 2.869 ENSMUST00000110117.1
Flrt2
fibronectin leucine rich transmembrane protein 2
chr5_-_122050102 2.781 ENSMUST00000154139.1
Cux2
cut-like homeobox 2
chr4_-_45084538 2.760 ENSMUST00000052236.6
Fbxo10
F-box protein 10
chr10_-_83337440 2.748 ENSMUST00000126617.1
Slc41a2
solute carrier family 41, member 2
chr7_-_130266237 2.732 ENSMUST00000117872.1
ENSMUST00000120187.1
Fgfr2

fibroblast growth factor receptor 2

chr7_-_130266191 2.727 ENSMUST00000122054.1
Fgfr2
fibroblast growth factor receptor 2
chr17_-_32788284 2.694 ENSMUST00000159086.2
Zfp871
zinc finger protein 871
chr12_-_24252181 2.691 ENSMUST00000169148.1
Gm9312
predicted gene 9312
chr4_-_123664725 2.641 ENSMUST00000147030.1
Macf1
microtubule-actin crosslinking factor 1
chr2_-_5714490 2.572 ENSMUST00000044009.7
Camk1d
calcium/calmodulin-dependent protein kinase ID
chr11_-_6065737 2.489 ENSMUST00000002817.5
ENSMUST00000109813.2
ENSMUST00000090443.3
Camk2b


calcium/calmodulin-dependent protein kinase II, beta


chr14_-_79771305 2.477 ENSMUST00000039568.5
Pcdh8
protocadherin 8
chr9_-_98033181 2.475 ENSMUST00000035027.6
Clstn2
calsyntenin 2
chr7_-_118243564 2.475 ENSMUST00000179047.1
ENSMUST00000032891.8
Smg1

SMG1 homolog, phosphatidylinositol 3-kinase-related kinase (C. elegans)

chr11_+_67455339 2.458 ENSMUST00000108681.1
Gas7
growth arrest specific 7
chr17_+_69969387 2.423 ENSMUST00000146730.1
Dlgap1
discs, large (Drosophila) homolog-associated protein 1
chr10_-_17947997 2.410 ENSMUST00000037879.6
Heca
headcase homolog (Drosophila)
chr7_+_113207465 2.377 ENSMUST00000047321.7
Arntl
aryl hydrocarbon receptor nuclear translocator-like
chr19_+_57611020 2.367 ENSMUST00000077282.5
Atrnl1
attractin like 1
chr10_-_83337845 2.347 ENSMUST00000039956.5
Slc41a2
solute carrier family 41, member 2
chr4_+_13743424 2.333 ENSMUST00000006761.3
Runx1t1
runt-related transcription factor 1; translocated to, 1 (cyclin D-related)
chr7_+_96210107 2.318 ENSMUST00000138760.1
Tenm4
teneurin transmembrane protein 4
chr10_+_58813359 2.307 ENSMUST00000135526.2
ENSMUST00000153031.1
Sh3rf3

SH3 domain containing ring finger 3

chr16_-_34573526 2.295 ENSMUST00000114961.1
Kalrn
kalirin, RhoGEF kinase
chr9_-_114933811 2.282 ENSMUST00000084853.3
Gpd1l
glycerol-3-phosphate dehydrogenase 1-like
chr16_-_52452465 2.267 ENSMUST00000170035.1
ENSMUST00000164728.1
Alcam

activated leukocyte cell adhesion molecule

chr7_-_78578308 2.232 ENSMUST00000039431.7
Ntrk3
neurotrophic tyrosine kinase, receptor, type 3
chr12_+_70825492 2.231 ENSMUST00000057859.7
Frmd6
FERM domain containing 6
chr10_+_13966268 2.216 ENSMUST00000015645.4
Hivep2
human immunodeficiency virus type I enhancer binding protein 2
chr10_-_116473875 2.189 ENSMUST00000068233.4
Kcnmb4
potassium large conductance calcium-activated channel, subfamily M, beta member 4
chr10_-_54075730 2.187 ENSMUST00000105469.1
ENSMUST00000003843.8
Man1a

mannosidase 1, alpha

chr3_+_63295815 2.179 ENSMUST00000029400.1
Mme
membrane metallo endopeptidase
chr17_+_83706170 2.126 ENSMUST00000067826.8
Mta3
metastasis associated 3
chr15_-_71727815 2.112 ENSMUST00000022953.8
Fam135b
family with sequence similarity 135, member B
chr8_-_73353477 2.107 ENSMUST00000119826.1
Large
like-glycosyltransferase
chr1_-_136260873 2.097 ENSMUST00000086395.5
Gpr25
G protein-coupled receptor 25
chr4_-_151861698 2.077 ENSMUST00000049790.7
Camta1
calmodulin binding transcription activator 1
chr15_-_44788016 2.022 ENSMUST00000090057.4
ENSMUST00000110269.1
Sybu

syntabulin (syntaxin-interacting)

chr6_+_21215472 2.018 ENSMUST00000081542.5
Kcnd2
potassium voltage-gated channel, Shal-related family, member 2
chr4_-_120747248 2.018 ENSMUST00000030376.7
Kcnq4
potassium voltage-gated channel, subfamily Q, member 4
chr5_-_139325616 2.002 ENSMUST00000110865.1
Adap1
ArfGAP with dual PH domains 1
chr13_-_47014814 1.993 ENSMUST00000052747.2
Nhlrc1
NHL repeat containing 1
chr10_-_81025521 1.982 ENSMUST00000144640.1
Diras1
DIRAS family, GTP-binding RAS-like 1
chr13_-_59557230 1.960 ENSMUST00000165370.1
ENSMUST00000109830.2
ENSMUST00000022040.6
ENSMUST00000171606.1
ENSMUST00000167096.1
ENSMUST00000166585.1
Agtpbp1





ATP/GTP binding protein 1





chr8_-_11312731 1.929 ENSMUST00000033898.9
Col4a1
collagen, type IV, alpha 1
chr11_-_75796048 1.915 ENSMUST00000021209.7
Doc2b
double C2, beta
chr19_+_16132812 1.903 ENSMUST00000025541.5
Gnaq
guanine nucleotide binding protein, alpha q polypeptide
chr2_+_127336152 1.900 ENSMUST00000028846.6
Dusp2
dual specificity phosphatase 2
chr9_+_26733728 1.893 ENSMUST00000160899.1
ENSMUST00000161431.1
ENSMUST00000159799.1
B3gat1


beta-1,3-glucuronyltransferase 1 (glucuronosyltransferase P)


chr15_-_95528228 1.893 ENSMUST00000075275.2
Nell2
NEL-like 2
chr19_-_24031006 1.885 ENSMUST00000096164.4
Fam189a2
family with sequence similarity 189, member A2
chr13_+_54949388 1.856 ENSMUST00000026994.7
ENSMUST00000109994.2
Unc5a

unc-5 homolog A (C. elegans)

chr12_-_109068173 1.851 ENSMUST00000073156.7
Begain
brain-enriched guanylate kinase-associated
chr7_+_57387304 1.848 ENSMUST00000085241.5
Gm9962
predicted gene 9962
chr7_-_31126945 1.845 ENSMUST00000098548.4
Scn1b
sodium channel, voltage-gated, type I, beta
chr15_-_43869993 1.840 ENSMUST00000067469.4
Tmem74
transmembrane protein 74
chr11_-_121388186 1.834 ENSMUST00000106107.2
Rab40b
Rab40b, member RAS oncogene family
chr5_+_144768536 1.827 ENSMUST00000128550.1
Trrap
transformation/transcription domain-associated protein
chr4_-_155222535 1.822 ENSMUST00000084103.3
ENSMUST00000030917.5
Ski

ski sarcoma viral oncogene homolog (avian)

chr4_+_129985098 1.792 ENSMUST00000106017.1
ENSMUST00000121049.1
Bai2

brain-specific angiogenesis inhibitor 2

chr17_+_83706137 1.786 ENSMUST00000112350.1
ENSMUST00000112349.2
ENSMUST00000112352.3
Mta3


metastasis associated 3


chr15_-_75566608 1.779 ENSMUST00000163116.1
ENSMUST00000023241.5
Ly6h

lymphocyte antigen 6 complex, locus H

chr11_+_84179792 1.772 ENSMUST00000137500.2
ENSMUST00000130012.2
Acaca

acetyl-Coenzyme A carboxylase alpha

chrX_-_162643575 1.765 ENSMUST00000101102.1
Reps2
RALBP1 associated Eps domain containing protein 2
chr3_-_53657339 1.764 ENSMUST00000091137.4
Frem2
Fras1 related extracellular matrix protein 2
chr12_-_79007276 1.761 ENSMUST00000056660.6
ENSMUST00000174721.1
Tmem229b

transmembrane protein 229B

chr16_-_85803106 1.759 ENSMUST00000023610.8
Adamts1
a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 1
chr2_-_27142429 1.758 ENSMUST00000151224.2
Fam163b
family with sequence similarity 163, member B
chr16_-_43979050 1.749 ENSMUST00000165648.1
ENSMUST00000036321.7
Zdhhc23

zinc finger, DHHC domain containing 23

chr8_+_125995102 1.738 ENSMUST00000046765.8
Kcnk1
potassium channel, subfamily K, member 1
chr10_-_54075702 1.727 ENSMUST00000105470.1
Man1a
mannosidase 1, alpha
chr12_+_3806513 1.700 ENSMUST00000172719.1
Dnmt3a
DNA methyltransferase 3A
chr18_+_51117754 1.692 ENSMUST00000116639.2
Prr16
proline rich 16
chr3_-_9833617 1.684 ENSMUST00000108384.2
Pag1
phosphoprotein associated with glycosphingolipid microdomains 1
chr2_+_92599671 1.683 ENSMUST00000065797.6
Chst1
carbohydrate (keratan sulfate Gal-6) sulfotransferase 1
chr11_+_35121126 1.675 ENSMUST00000069837.3
Slit3
slit homolog 3 (Drosophila)
chr9_+_51765325 1.666 ENSMUST00000065496.5
Arhgap20
Rho GTPase activating protein 20
chrX_-_162643629 1.661 ENSMUST00000112334.1
Reps2
RALBP1 associated Eps domain containing protein 2
chr19_+_10041548 1.646 ENSMUST00000115995.2
Fads3
fatty acid desaturase 3
chr8_+_111094630 1.634 ENSMUST00000135302.1
ENSMUST00000039333.3
Pdpr

pyruvate dehydrogenase phosphatase regulatory subunit

chr13_-_34345174 1.631 ENSMUST00000040336.5
Slc22a23
solute carrier family 22, member 23
chr15_+_7129557 1.629 ENSMUST00000067190.5
ENSMUST00000164529.1
Lifr

leukemia inhibitory factor receptor

chr1_+_45795485 1.624 ENSMUST00000147308.1
Wdr75
WD repeat domain 75
chr1_+_34579693 1.616 ENSMUST00000052670.8
Amer3
APC membrane recruitment 3
chr1_+_23762003 1.612 ENSMUST00000140583.1
B3gat2
beta-1,3-glucuronyltransferase 2 (glucuronosyltransferase S)
chr4_+_102087543 1.598 ENSMUST00000106911.1
Pde4b
phosphodiesterase 4B, cAMP specific
chr18_-_61911783 1.590 ENSMUST00000049378.8
ENSMUST00000166783.1
Ablim3

actin binding LIM protein family, member 3

chr10_-_68278713 1.584 ENSMUST00000020106.7
Arid5b
AT rich interactive domain 5B (MRF1-like)
chr4_-_136835843 1.581 ENSMUST00000105846.2
ENSMUST00000059287.7
ENSMUST00000105845.2
Ephb2


Eph receptor B2


chr7_-_122067263 1.574 ENSMUST00000033159.3
Ears2
glutamyl-tRNA synthetase 2 (mitochondrial)(putative)
chr5_-_122049822 1.573 ENSMUST00000111752.3
Cux2
cut-like homeobox 2
chr2_-_24763047 1.572 ENSMUST00000100348.3
ENSMUST00000041342.5
ENSMUST00000114447.1
ENSMUST00000102939.2
ENSMUST00000070864.7
Cacna1b




calcium channel, voltage-dependent, N type, alpha 1B subunit




chr17_-_24205514 1.568 ENSMUST00000097376.3
ENSMUST00000168410.2
ENSMUST00000167791.2
ENSMUST00000040474.7
Tbc1d24



TBC1 domain family, member 24



chr11_+_120721543 1.561 ENSMUST00000142229.1
Rac3
RAS-related C3 botulinum substrate 3
chr4_-_149307506 1.559 ENSMUST00000055647.8
ENSMUST00000030806.5
ENSMUST00000060537.6
Kif1b


kinesin family member 1B


chr14_+_62555737 1.557 ENSMUST00000039064.7
Fam124a
family with sequence similarity 124, member A
chr17_-_78418083 1.555 ENSMUST00000070039.7
ENSMUST00000112487.1
Fez2

fasciculation and elongation protein zeta 2 (zygin II)

chr10_-_80844025 1.548 ENSMUST00000053986.7
Lingo3
leucine rich repeat and Ig domain containing 3
chr5_+_105415738 1.546 ENSMUST00000112707.1
Lrrc8b
leucine rich repeat containing 8 family, member B
chr5_+_110544326 1.535 ENSMUST00000040001.7
Galnt9
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 9
chr2_+_155775333 1.532 ENSMUST00000029141.5
Mmp24
matrix metallopeptidase 24
chr19_+_4099998 1.529 ENSMUST00000049658.7
Pitpnm1
phosphatidylinositol transfer protein, membrane-associated 1
chr10_+_19934472 1.523 ENSMUST00000095806.3
ENSMUST00000120259.1
Map3k5

mitogen-activated protein kinase kinase kinase 5

chr17_+_5492558 1.518 ENSMUST00000089185.4
Zdhhc14
zinc finger, DHHC domain containing 14
chr2_-_132145057 1.503 ENSMUST00000028815.8
Slc23a2
solute carrier family 23 (nucleobase transporters), member 2
chr1_-_190979280 1.500 ENSMUST00000166139.1
Vash2
vasohibin 2
chr10_-_76345254 1.498 ENSMUST00000036033.7
ENSMUST00000160048.1
ENSMUST00000105417.3
Dip2a


DIP2 disco-interacting protein 2 homolog A (Drosophila)


chr13_-_59556845 1.496 ENSMUST00000170378.1
ENSMUST00000169434.1
Agtpbp1

ATP/GTP binding protein 1

chr8_+_11312805 1.493 ENSMUST00000033899.7
Col4a2
collagen, type IV, alpha 2
chr14_-_121797670 1.480 ENSMUST00000100299.3
Dock9
dedicator of cytokinesis 9
chr17_+_78200240 1.474 ENSMUST00000112498.2
Crim1
cysteine rich transmembrane BMP regulator 1 (chordin like)
chr3_+_117575268 1.472 ENSMUST00000039564.6
4833424O15Rik
RIKEN cDNA 4833424O15 gene
chr12_-_76822510 1.471 ENSMUST00000021459.7
Rab15
RAB15, member RAS oncogene family
chr2_+_149830840 1.460 ENSMUST00000109934.1
ENSMUST00000140870.1
Syndig1

synapse differentiation inducing 1

chr5_+_117781017 1.458 ENSMUST00000138579.2
Nos1
nitric oxide synthase 1, neuronal
chr12_-_85151264 1.453 ENSMUST00000019379.7
Rps6kl1
ribosomal protein S6 kinase-like 1
chr6_+_4902913 1.451 ENSMUST00000175889.1
ENSMUST00000168998.2
Ppp1r9a

protein phosphatase 1, regulatory (inhibitor) subunit 9A

chr9_-_42264200 1.448 ENSMUST00000169609.1
Sc5d
sterol-C5-desaturase (fungal ERG3, delta-5-desaturase) homolog (S. cerevisae)
chr2_+_90885860 1.447 ENSMUST00000111466.2
C1qtnf4
C1q and tumor necrosis factor related protein 4
chr5_+_142401484 1.446 ENSMUST00000072837.5
Foxk1
forkhead box K1
chr16_-_52452654 1.439 ENSMUST00000168071.1
Alcam
activated leukocyte cell adhesion molecule
chr6_+_99692679 1.418 ENSMUST00000101122.1
Gpr27
G protein-coupled receptor 27
chr7_-_57509995 1.416 ENSMUST00000068456.6
Gabra5
gamma-aminobutyric acid (GABA) A receptor, subunit alpha 5
chr2_+_117121638 1.413 ENSMUST00000110901.1
Spred1
sprouty protein with EVH-1 domain 1, related sequence
chr10_+_52690496 1.399 ENSMUST00000105473.2
Slc35f1
solute carrier family 35, member F1
chr12_-_81333129 1.399 ENSMUST00000085238.6
ENSMUST00000182208.1
Slc8a3

solute carrier family 8 (sodium/calcium exchanger), member 3

chr19_+_37550397 1.395 ENSMUST00000066439.6
Exoc6
exocyst complex component 6
chr15_-_79804717 1.393 ENSMUST00000023057.8
Nptxr
neuronal pentraxin receptor
chr11_-_72489904 1.389 ENSMUST00000045303.3
Spns2
spinster homolog 2
chr3_+_141465592 1.388 ENSMUST00000130636.1
Unc5c
unc-5 homolog C (C. elegans)
chr9_+_122117258 1.387 ENSMUST00000146832.1
ENSMUST00000139181.1
Snrk

SNF related kinase

chr1_+_33908172 1.386 ENSMUST00000182513.1
ENSMUST00000183034.1
Dst

dystonin

chr3_-_109027600 1.383 ENSMUST00000171143.1
Fam102b
family with sequence similarity 102, member B
chr10_-_81025406 1.383 ENSMUST00000055125.4
Diras1
DIRAS family, GTP-binding RAS-like 1
chr2_-_3332566 1.378 ENSMUST00000062672.6
Rpp38
ribonuclease P/MRP 38 subunit
chr3_+_145987835 1.378 ENSMUST00000039517.6
Syde2
synapse defective 1, Rho GTPase, homolog 2 (C. elegans)
chr5_+_110879788 1.376 ENSMUST00000156290.2
ENSMUST00000040111.9
Ttc28

tetratricopeptide repeat domain 28

chr5_+_150259922 1.364 ENSMUST00000087204.5
Fry
furry homolog (Drosophila)
chr12_-_23968845 1.364 ENSMUST00000171153.1
Gm17330
predicted gene, 17330
chr17_-_26201363 1.363 ENSMUST00000121959.1
Arhgdig
Rho GDP dissociation inhibitor (GDI) gamma
chr5_-_136567307 1.354 ENSMUST00000004097.9
Cux1
cut-like homeobox 1
chr14_-_65953728 1.349 ENSMUST00000042046.3
Scara3
scavenger receptor class A, member 3
chr2_-_77816758 1.340 ENSMUST00000111831.1
Zfp385b
zinc finger protein 385B
chr1_+_132007606 1.340 ENSMUST00000086556.5
Elk4
ELK4, member of ETS oncogene family
chr11_+_32455362 1.335 ENSMUST00000051053.4
Ubtd2
ubiquitin domain containing 2
chr5_+_135023482 1.334 ENSMUST00000005509.4
Stx1a
syntaxin 1A (brain)
chr5_-_24030297 1.332 ENSMUST00000101513.2
Fam126a
family with sequence similarity 126, member A
chr12_-_22623087 1.327 ENSMUST00000171036.1
Gm17391
predicted gene, 17391
chr4_+_85205417 1.324 ENSMUST00000030212.8
ENSMUST00000107189.1
ENSMUST00000107184.1
Sh3gl2


SH3-domain GRB2-like 2


chr6_-_142964404 1.315 ENSMUST00000032421.3
St8sia1
ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 1
chr16_-_4420416 1.314 ENSMUST00000120080.1
Adcy9
adenylate cyclase 9
chr5_-_52471534 1.314 ENSMUST00000059428.5
Ccdc149
coiled-coil domain containing 149
chr7_+_66839752 1.307 ENSMUST00000107478.1
Adamts17
a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 17
chr4_-_6990774 1.304 ENSMUST00000039987.3
Tox
thymocyte selection-associated high mobility group box
chr4_-_151861762 1.303 ENSMUST00000097774.2
Camta1
calmodulin binding transcription activator 1
chr12_+_19606929 1.298 ENSMUST00000105167.1
Gm9257
predicted gene 9257

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
2.3 7.0 GO:0032430 inhibitory G-protein coupled receptor phosphorylation(GO:0002030) positive regulation of phospholipase A2 activity(GO:0032430) activation of meiosis involved in egg activation(GO:0060466)
1.8 5.5 GO:0035604 fibroblast growth factor receptor signaling pathway involved in negative regulation of apoptotic process in bone marrow(GO:0035602) fibroblast growth factor receptor signaling pathway involved in hemopoiesis(GO:0035603) fibroblast growth factor receptor signaling pathway involved in positive regulation of cell proliferation in bone marrow(GO:0035604) coronal suture morphogenesis(GO:0060365) squamous basal epithelial stem cell differentiation involved in prostate gland acinus development(GO:0060529)
1.5 7.6 GO:0071692 protein localization to extracellular region(GO:0071692) maintenance of protein location in extracellular region(GO:0071694)
1.3 9.3 GO:0070494 regulation of thrombin receptor signaling pathway(GO:0070494) negative regulation of thrombin receptor signaling pathway(GO:0070495)
1.2 3.6 GO:1902630 regulation of membrane hyperpolarization(GO:1902630)
1.2 3.6 GO:1900149 positive regulation of Schwann cell migration(GO:1900149)
1.1 3.4 GO:0046168 glycerol-3-phosphate catabolic process(GO:0046168)
1.0 2.0 GO:0032227 negative regulation of synaptic transmission, dopaminergic(GO:0032227)
1.0 3.8 GO:0086046 membrane depolarization during SA node cell action potential(GO:0086046)
0.9 2.8 GO:1904049 negative regulation of spontaneous neurotransmitter secretion(GO:1904049)
0.9 1.8 GO:0086047 membrane depolarization during Purkinje myocyte cell action potential(GO:0086047)
0.9 2.8 GO:0071492 cellular response to UV-A(GO:0071492)
0.9 2.7 GO:0070650 actin filament bundle distribution(GO:0070650)
0.9 3.5 GO:0035609 C-terminal protein deglutamylation(GO:0035609)
0.9 0.9 GO:0035844 cloaca development(GO:0035844)
0.8 3.2 GO:0070305 response to cGMP(GO:0070305) cellular response to cGMP(GO:0071321)
0.8 3.2 GO:0021564 glossopharyngeal nerve development(GO:0021563) vagus nerve development(GO:0021564)
0.8 2.4 GO:0090403 oxidative stress-induced premature senescence(GO:0090403)
0.8 4.7 GO:2000672 negative regulation of motor neuron apoptotic process(GO:2000672)
0.8 0.8 GO:0010543 regulation of platelet activation(GO:0010543) negative regulation of platelet activation(GO:0010544) regulation of platelet aggregation(GO:0090330) negative regulation of platelet aggregation(GO:0090331)
0.7 2.2 GO:0048687 positive regulation of sprouting of injured axon(GO:0048687) positive regulation of axon extension involved in regeneration(GO:0048691)
0.7 2.2 GO:0015772 disaccharide transport(GO:0015766) sucrose transport(GO:0015770) oligosaccharide transport(GO:0015772)
0.7 2.2 GO:0071317 cellular response to isoquinoline alkaloid(GO:0071317)
0.7 12.6 GO:0021684 cerebellar granular layer formation(GO:0021684) cerebellar granule cell differentiation(GO:0021707)
0.7 2.1 GO:0016256 N-glycan processing to lysosome(GO:0016256)
0.7 3.3 GO:0010991 negative regulation of SMAD protein complex assembly(GO:0010991)
0.6 1.2 GO:0097112 gamma-aminobutyric acid receptor clustering(GO:0097112)
0.6 2.4 GO:1905167 positive regulation of lysosomal protein catabolic process(GO:1905167)
0.6 2.3 GO:0032289 central nervous system myelin formation(GO:0032289)
0.6 4.5 GO:0033564 anterior/posterior axon guidance(GO:0033564)
0.6 0.6 GO:0006103 2-oxoglutarate metabolic process(GO:0006103)
0.6 1.1 GO:0050703 interleukin-1 alpha secretion(GO:0050703)
0.5 1.6 GO:0038165 oncostatin-M-mediated signaling pathway(GO:0038165)
0.5 1.1 GO:2000344 positive regulation of acrosome reaction(GO:2000344)
0.5 1.5 GO:0015882 L-ascorbic acid transport(GO:0015882) transepithelial L-ascorbic acid transport(GO:0070904)
0.5 6.5 GO:1901898 negative regulation of relaxation of cardiac muscle(GO:1901898)
0.5 1.5 GO:0099548 drug catabolic process(GO:0042737) exogenous drug catabolic process(GO:0042738) retrograde trans-synaptic signaling by soluble gas(GO:0098923) trans-synaptic signaling by nitric oxide(GO:0099548)
0.5 0.5 GO:1903977 positive regulation of glial cell migration(GO:1903977)
0.5 2.9 GO:0015015 heparan sulfate proteoglycan biosynthetic process, enzymatic modification(GO:0015015)
0.5 1.4 GO:1900738 positive regulation of phospholipase C-activating G-protein coupled receptor signaling pathway(GO:1900738)
0.5 1.8 GO:0021586 pons maturation(GO:0021586)
0.4 2.2 GO:1990034 calcium ion export from cell(GO:1990034)
0.4 1.8 GO:0044268 multicellular organismal protein metabolic process(GO:0044268)
0.4 3.5 GO:0005513 detection of calcium ion(GO:0005513)
0.4 1.3 GO:0098528 skeletal muscle fiber differentiation(GO:0098528)
0.4 6.0 GO:0007190 activation of adenylate cyclase activity(GO:0007190)
0.4 1.7 GO:1903294 regulation of glutamate secretion, neurotransmission(GO:1903294) positive regulation of glutamate secretion, neurotransmission(GO:1903296)
0.4 11.1 GO:0030204 chondroitin sulfate metabolic process(GO:0030204)
0.4 1.7 GO:2000211 regulation of glutamate metabolic process(GO:2000211)
0.4 2.1 GO:0043987 histone H3-S10 phosphorylation(GO:0043987)
0.4 2.9 GO:0060137 maternal process involved in parturition(GO:0060137)
0.4 2.0 GO:0060075 regulation of resting membrane potential(GO:0060075)
0.4 0.8 GO:0061744 motor behavior(GO:0061744)
0.4 1.2 GO:0042271 susceptibility to natural killer cell mediated cytotoxicity(GO:0042271)
0.4 2.0 GO:0060158 phospholipase C-activating dopamine receptor signaling pathway(GO:0060158)
0.4 1.6 GO:0001956 positive regulation of neurotransmitter secretion(GO:0001956)
0.4 1.6 GO:0097118 neuroligin clustering involved in postsynaptic membrane assembly(GO:0097118)
0.4 0.8 GO:0050975 sensory perception of touch(GO:0050975)
0.4 3.4 GO:0045721 negative regulation of gluconeogenesis(GO:0045721)
0.4 1.9 GO:0072368 regulation of lipid transport by negative regulation of transcription from RNA polymerase II promoter(GO:0072368)
0.4 1.1 GO:1990927 calcium ion regulated lysosome exocytosis(GO:1990927)
0.4 2.6 GO:0060267 positive regulation of respiratory burst(GO:0060267)
0.4 2.5 GO:1990416 cellular response to brain-derived neurotrophic factor stimulus(GO:1990416)
0.3 1.7 GO:0010626 negative regulation of Schwann cell proliferation(GO:0010626)
0.3 1.0 GO:1904978 regulation of endosome organization(GO:1904978) positive regulation of endosome organization(GO:1904980)
0.3 1.0 GO:0014053 negative regulation of gamma-aminobutyric acid secretion(GO:0014053)
0.3 1.3 GO:0006668 sphinganine-1-phosphate metabolic process(GO:0006668)
0.3 1.9 GO:1901552 positive regulation of endothelial cell development(GO:1901552) positive regulation of establishment of endothelial barrier(GO:1903142)
0.3 5.8 GO:0006491 N-glycan processing(GO:0006491)
0.3 1.9 GO:0042276 error-prone translesion synthesis(GO:0042276)
0.3 1.0 GO:0014916 regulation of lung blood pressure(GO:0014916) negative regulation of cell proliferation involved in heart morphogenesis(GO:2000137)
0.3 1.0 GO:0045204 MAPK export from nucleus(GO:0045204)
0.3 1.2 GO:0036015 response to interleukin-3(GO:0036015) cellular response to interleukin-3(GO:0036016)
0.3 0.6 GO:1904529 regulation of actin filament binding(GO:1904529) regulation of actin binding(GO:1904616)
0.3 0.9 GO:1905169 protein localization to phagocytic vesicle(GO:1905161) regulation of protein localization to phagocytic vesicle(GO:1905169) positive regulation of protein localization to phagocytic vesicle(GO:1905171)
0.3 2.4 GO:0031053 primary miRNA processing(GO:0031053)
0.3 2.4 GO:0070314 G1 to G0 transition(GO:0070314)
0.3 0.9 GO:1905223 epicardium morphogenesis(GO:1905223)
0.3 1.2 GO:0051866 general adaptation syndrome(GO:0051866)
0.3 0.9 GO:0014834 skeletal muscle satellite cell maintenance involved in skeletal muscle regeneration(GO:0014834)
0.3 0.6 GO:0051639 actin filament network formation(GO:0051639)
0.3 0.9 GO:0007352 zygotic specification of dorsal/ventral axis(GO:0007352)
0.3 0.9 GO:2000705 regulation of dense core granule biogenesis(GO:2000705)
0.3 1.7 GO:0070100 negative regulation of chemokine-mediated signaling pathway(GO:0070100)
0.3 3.9 GO:0043517 positive regulation of DNA damage response, signal transduction by p53 class mediator(GO:0043517)
0.3 5.0 GO:0048172 regulation of short-term neuronal synaptic plasticity(GO:0048172)
0.3 1.9 GO:0061304 retinal blood vessel morphogenesis(GO:0061304)
0.3 1.6 GO:0090070 positive regulation of ribosome biogenesis(GO:0090070) positive regulation of rRNA processing(GO:2000234)
0.3 0.8 GO:0010512 negative regulation of phosphatidylinositol biosynthetic process(GO:0010512)
0.3 1.1 GO:0002924 negative regulation of humoral immune response mediated by circulating immunoglobulin(GO:0002924)
0.3 1.1 GO:0019919 peptidyl-arginine methylation, to asymmetrical-dimethyl arginine(GO:0019919)
0.3 0.8 GO:0046959 habituation(GO:0046959)
0.3 2.6 GO:0006620 posttranslational protein targeting to membrane(GO:0006620)
0.3 3.9 GO:0045956 positive regulation of calcium ion-dependent exocytosis(GO:0045956)
0.3 7.3 GO:0007214 gamma-aminobutyric acid signaling pathway(GO:0007214)
0.3 1.0 GO:1904425 negative regulation of GTP binding(GO:1904425)
0.3 0.8 GO:1904956 response to heparin(GO:0071503) cellular response to heparin(GO:0071504) regulation of midbrain dopaminergic neuron differentiation(GO:1904956) regulation of planar cell polarity pathway involved in axis elongation(GO:2000040) negative regulation of planar cell polarity pathway involved in axis elongation(GO:2000041)
0.3 1.0 GO:0070358 actin polymerization-dependent cell motility(GO:0070358)
0.3 0.5 GO:0001923 B-1 B cell differentiation(GO:0001923)
0.3 3.8 GO:0048148 behavioral response to cocaine(GO:0048148)
0.3 1.0 GO:2000313 fibroblast growth factor receptor signaling pathway involved in neural plate anterior/posterior pattern formation(GO:0060825) regulation of fibroblast growth factor receptor signaling pathway involved in neural plate anterior/posterior pattern formation(GO:2000313)
0.3 1.3 GO:0035063 nuclear speck organization(GO:0035063)
0.2 1.7 GO:0070127 tRNA aminoacylation for mitochondrial protein translation(GO:0070127)
0.2 1.5 GO:0051964 negative regulation of synapse assembly(GO:0051964)
0.2 1.2 GO:0060124 positive regulation of growth hormone secretion(GO:0060124)
0.2 0.9 GO:1902626 assembly of large subunit precursor of preribosome(GO:1902626)
0.2 0.7 GO:0051933 regulation of DNA-templated transcription, termination(GO:0031554) amino acid neurotransmitter reuptake(GO:0051933) glutamate reuptake(GO:0051935)
0.2 20.2 GO:0051965 positive regulation of synapse assembly(GO:0051965)
0.2 0.7 GO:0060854 patterning of lymph vessels(GO:0060854)
0.2 0.7 GO:0010730 negative regulation of hydrogen peroxide metabolic process(GO:0010727) negative regulation of hydrogen peroxide biosynthetic process(GO:0010730)
0.2 0.9 GO:0046391 5-phosphoribose 1-diphosphate biosynthetic process(GO:0006015) 5-phosphoribose 1-diphosphate metabolic process(GO:0046391)
0.2 0.2 GO:0090244 Wnt signaling pathway involved in somitogenesis(GO:0090244)
0.2 1.3 GO:0051045 negative regulation of membrane protein ectodomain proteolysis(GO:0051045)
0.2 2.0 GO:0006686 sphingomyelin biosynthetic process(GO:0006686)
0.2 0.9 GO:0003278 apoptotic process involved in heart morphogenesis(GO:0003278)
0.2 0.9 GO:0097477 lateral motor column neuron migration(GO:0097477) positive regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity(GO:2000969)
0.2 1.7 GO:0045541 negative regulation of cholesterol biosynthetic process(GO:0045541) negative regulation of cholesterol metabolic process(GO:0090206)
0.2 1.3 GO:0048069 eye pigmentation(GO:0048069)
0.2 0.2 GO:0021882 regulation of transcription from RNA polymerase II promoter involved in forebrain neuron fate commitment(GO:0021882)
0.2 1.2 GO:0071494 cellular response to UV-C(GO:0071494)
0.2 0.6 GO:0046341 CDP-diacylglycerol metabolic process(GO:0046341)
0.2 1.2 GO:1901897 regulation of relaxation of cardiac muscle(GO:1901897)
0.2 0.6 GO:0071544 diphosphoinositol polyphosphate catabolic process(GO:0071544)
0.2 0.8 GO:0071475 cellular hyperosmotic salinity response(GO:0071475)
0.2 0.8 GO:1900368 regulation of RNA interference(GO:1900368)
0.2 0.6 GO:1902219 negative regulation of intrinsic apoptotic signaling pathway in response to osmotic stress(GO:1902219)
0.2 0.6 GO:0060478 acrosomal vesicle exocytosis(GO:0060478)
0.2 1.2 GO:0055003 cardiac myofibril assembly(GO:0055003)
0.2 1.3 GO:0033031 positive regulation of neutrophil apoptotic process(GO:0033031)
0.2 0.8 GO:0009414 response to water deprivation(GO:0009414)
0.2 1.7 GO:0050882 voluntary musculoskeletal movement(GO:0050882)
0.2 0.9 GO:0033625 positive regulation of integrin activation(GO:0033625)
0.2 1.5 GO:0030322 stabilization of membrane potential(GO:0030322)
0.2 1.1 GO:0016266 O-glycan processing(GO:0016266)
0.2 1.3 GO:0021894 cerebral cortex GABAergic interneuron development(GO:0021894)
0.2 2.4 GO:0070842 aggresome assembly(GO:0070842)
0.2 1.5 GO:0071318 cellular response to ATP(GO:0071318)
0.2 1.1 GO:0099590 neurotransmitter receptor internalization(GO:0099590)
0.2 0.7 GO:0031133 regulation of axon diameter(GO:0031133)
0.2 1.8 GO:1903818 positive regulation of voltage-gated potassium channel activity(GO:1903818)
0.2 1.2 GO:0048227 plasma membrane to endosome transport(GO:0048227)
0.2 0.3 GO:0001954 positive regulation of cell-matrix adhesion(GO:0001954)
0.2 0.5 GO:1904017 response to Thyroglobulin triiodothyronine(GO:1904016) cellular response to Thyroglobulin triiodothyronine(GO:1904017)
0.2 3.3 GO:0045793 positive regulation of cell size(GO:0045793)
0.2 4.7 GO:0010971 positive regulation of G2/M transition of mitotic cell cycle(GO:0010971)
0.2 0.7 GO:0003430 growth plate cartilage chondrocyte growth(GO:0003430)
0.2 1.1 GO:0034058 endosomal vesicle fusion(GO:0034058)
0.2 0.8 GO:0000480 endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000480)
0.2 1.4 GO:0090043 regulation of tubulin deacetylation(GO:0090043)
0.2 0.5 GO:0002946 tRNA C5-cytosine methylation(GO:0002946)
0.2 0.5 GO:0005981 regulation of glycogen catabolic process(GO:0005981)
0.2 0.9 GO:0051096 positive regulation of helicase activity(GO:0051096)
0.2 0.3 GO:0035526 retrograde transport, plasma membrane to Golgi(GO:0035526)
0.2 1.1 GO:1900042 positive regulation of interleukin-2 secretion(GO:1900042)
0.2 1.6 GO:1902902 negative regulation of autophagosome assembly(GO:1902902)
0.2 0.3 GO:0040010 positive regulation of growth rate(GO:0040010)
0.2 1.6 GO:0050965 detection of temperature stimulus involved in sensory perception(GO:0050961) detection of temperature stimulus involved in sensory perception of pain(GO:0050965)
0.2 1.4 GO:0008090 retrograde axonal transport(GO:0008090)
0.2 0.9 GO:0018344 protein geranylgeranylation(GO:0018344)
0.2 1.1 GO:0035887 aortic smooth muscle cell differentiation(GO:0035887)
0.2 0.8 GO:1903527 positive regulation of membrane tubulation(GO:1903527)
0.2 0.5 GO:1903538 meiotic cell cycle process involved in oocyte maturation(GO:1903537) regulation of meiotic cell cycle process involved in oocyte maturation(GO:1903538)
0.1 0.7 GO:0090527 actin filament reorganization(GO:0090527)
0.1 3.5 GO:0046854 phosphatidylinositol phosphorylation(GO:0046854)
0.1 0.9 GO:0045218 zonula adherens maintenance(GO:0045218)
0.1 2.0 GO:0045974 miRNA mediated inhibition of translation(GO:0035278) negative regulation of translation, ncRNA-mediated(GO:0040033) regulation of translation, ncRNA-mediated(GO:0045974)
0.1 0.1 GO:1905165 regulation of lysosomal protein catabolic process(GO:1905165)
0.1 1.6 GO:0097186 amelogenesis(GO:0097186)
0.1 0.7 GO:0098703 calcium ion import across plasma membrane(GO:0098703) calcium ion import into cell(GO:1990035)
0.1 0.4 GO:1902022 L-lysine transport(GO:1902022)
0.1 1.3 GO:0048680 positive regulation of axon regeneration(GO:0048680)
0.1 1.8 GO:0071625 vocalization behavior(GO:0071625)
0.1 1.4 GO:0060347 heart trabecula formation(GO:0060347)
0.1 7.4 GO:0034605 cellular response to heat(GO:0034605)
0.1 1.7 GO:0006012 galactose metabolic process(GO:0006012)
0.1 1.2 GO:0002903 negative regulation of B cell apoptotic process(GO:0002903)
0.1 0.7 GO:0098909 regulation of cardiac muscle cell action potential involved in regulation of contraction(GO:0098909)
0.1 1.6 GO:0021957 corticospinal tract morphogenesis(GO:0021957)
0.1 0.4 GO:0015886 heme transport(GO:0015886)
0.1 4.1 GO:0006904 vesicle docking involved in exocytosis(GO:0006904)
0.1 0.8 GO:0006646 phosphatidylethanolamine biosynthetic process(GO:0006646)
0.1 0.9 GO:0030813 positive regulation of nucleotide catabolic process(GO:0030813) positive regulation of glycolytic process(GO:0045821) positive regulation of cofactor metabolic process(GO:0051194) positive regulation of coenzyme metabolic process(GO:0051197)
0.1 0.8 GO:2001184 regulation of interleukin-12 secretion(GO:2001182) positive regulation of interleukin-12 secretion(GO:2001184)
0.1 0.8 GO:0060718 chorionic trophoblast cell differentiation(GO:0060718)
0.1 0.8 GO:0031034 myosin filament assembly(GO:0031034)
0.1 0.4 GO:0035799 ureter maturation(GO:0035799)
0.1 0.3 GO:0070278 extracellular matrix constituent secretion(GO:0070278)
0.1 0.4 GO:0007171 activation of transmembrane receptor protein tyrosine kinase activity(GO:0007171)
0.1 0.5 GO:1903898 positive regulation of translation in response to endoplasmic reticulum stress(GO:0036493) negative regulation of PERK-mediated unfolded protein response(GO:1903898)
0.1 0.6 GO:0090669 snoRNA guided rRNA pseudouridine synthesis(GO:0000454) telomerase RNA stabilization(GO:0090669)
0.1 0.9 GO:2000786 positive regulation of autophagosome assembly(GO:2000786)
0.1 0.4 GO:0031293 membrane protein intracellular domain proteolysis(GO:0031293)
0.1 0.5 GO:0036491 regulation of translation initiation in response to endoplasmic reticulum stress(GO:0036491) eiF2alpha phosphorylation in response to endoplasmic reticulum stress(GO:0036492)
0.1 0.2 GO:0070427 nucleotide-binding oligomerization domain containing 1 signaling pathway(GO:0070427)
0.1 0.6 GO:0043696 dedifferentiation(GO:0043696) cell dedifferentiation(GO:0043697)
0.1 0.4 GO:0035621 ER to Golgi ceramide transport(GO:0035621) ceramide transport(GO:0035627)
0.1 1.1 GO:1903861 positive regulation of dendrite extension(GO:1903861)
0.1 0.2 GO:0071649 regulation of chemokine (C-C motif) ligand 5 production(GO:0071649)
0.1 2.6 GO:0045026 plasma membrane fusion(GO:0045026)
0.1 0.7 GO:0001574 ganglioside biosynthetic process(GO:0001574)
0.1 0.6 GO:1900170 negative regulation of glucocorticoid mediated signaling pathway(GO:1900170)
0.1 0.4 GO:0010641 positive regulation of platelet-derived growth factor receptor signaling pathway(GO:0010641)
0.1 1.3 GO:0006968 cellular defense response(GO:0006968)
0.1 0.3 GO:0035811 negative regulation of urine volume(GO:0035811)
0.1 2.2 GO:0048791 calcium ion-regulated exocytosis of neurotransmitter(GO:0048791)
0.1 3.7 GO:0008045 motor neuron axon guidance(GO:0008045)
0.1 1.1 GO:0008063 Toll signaling pathway(GO:0008063)
0.1 0.5 GO:0019985 translesion synthesis(GO:0019985)
0.1 0.5 GO:0035624 receptor transactivation(GO:0035624) epidermal growth factor-activated receptor transactivation by G-protein coupled receptor signaling pathway(GO:0035625)
0.1 1.0 GO:0010459 negative regulation of heart rate(GO:0010459)
0.1 0.8 GO:0006561 proline biosynthetic process(GO:0006561)
0.1 1.1 GO:0060394 negative regulation of pathway-restricted SMAD protein phosphorylation(GO:0060394)
0.1 1.1 GO:0035873 lactate transport(GO:0015727) lactate transmembrane transport(GO:0035873) plasma membrane lactate transport(GO:0035879)
0.1 1.5 GO:1900745 positive regulation of p38MAPK cascade(GO:1900745)
0.1 1.4 GO:0000083 regulation of transcription involved in G1/S transition of mitotic cell cycle(GO:0000083)
0.1 0.4 GO:0045741 positive regulation of epidermal growth factor-activated receptor activity(GO:0045741)
0.1 0.3 GO:0048294 negative regulation of isotype switching to IgE isotypes(GO:0048294)
0.1 0.7 GO:0030718 germ-line stem cell population maintenance(GO:0030718)
0.1 0.6 GO:0006020 inositol metabolic process(GO:0006020)
0.1 0.7 GO:1990118 sodium ion import across plasma membrane(GO:0098719) sodium ion import into cell(GO:1990118)
0.1 0.4 GO:1902514 regulation of calcium ion transmembrane transport via high voltage-gated calcium channel(GO:1902514)
0.1 0.4 GO:0035754 B cell chemotaxis(GO:0035754)
0.1 0.9 GO:0033008 positive regulation of mast cell activation involved in immune response(GO:0033008) positive regulation of mast cell degranulation(GO:0043306)
0.1 0.4 GO:0030202 heparin metabolic process(GO:0030202)
0.1 0.8 GO:0006071 glycerol metabolic process(GO:0006071)
0.1 1.4 GO:0008272 sulfate transport(GO:0008272)
0.1 0.8 GO:0038026 reelin-mediated signaling pathway(GO:0038026)
0.1 0.3 GO:0072382 minus-end-directed vesicle transport along microtubule(GO:0072382)
0.1 1.2 GO:1900383 regulation of synaptic plasticity by receptor localization to synapse(GO:1900383)
0.1 0.5 GO:2000601 positive regulation of Arp2/3 complex-mediated actin nucleation(GO:2000601)
0.1 0.2 GO:0001920 negative regulation of receptor recycling(GO:0001920)
0.1 0.5 GO:0033299 secretion of lysosomal enzymes(GO:0033299)
0.1 0.3 GO:0070086 ubiquitin-dependent endocytosis(GO:0070086)
0.1 1.1 GO:0006488 dolichol-linked oligosaccharide biosynthetic process(GO:0006488)
0.1 0.3 GO:0045869 negative regulation of single stranded viral RNA replication via double stranded DNA intermediate(GO:0045869)
0.1 0.2 GO:0010694 positive regulation of alkaline phosphatase activity(GO:0010694)
0.1 0.6 GO:0034773 histone H4-K20 trimethylation(GO:0034773)
0.1 1.5 GO:0038063 collagen-activated tyrosine kinase receptor signaling pathway(GO:0038063)
0.1 1.1 GO:0001964 startle response(GO:0001964)
0.1 0.6 GO:0030950 establishment or maintenance of actin cytoskeleton polarity(GO:0030950)
0.1 0.4 GO:0017183 peptidyl-diphthamide metabolic process(GO:0017182) peptidyl-diphthamide biosynthetic process from peptidyl-histidine(GO:0017183)
0.1 0.4 GO:0035927 RNA import into mitochondrion(GO:0035927)
0.1 0.4 GO:0006481 C-terminal protein methylation(GO:0006481)
0.1 0.5 GO:0090343 establishment or maintenance of microtubule cytoskeleton polarity(GO:0030951) positive regulation of cell aging(GO:0090343)
0.1 1.0 GO:1901798 positive regulation of signal transduction by p53 class mediator(GO:1901798)
0.1 5.9 GO:0030032 lamellipodium assembly(GO:0030032)
0.1 0.3 GO:1903760 regulation of voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization(GO:1903760) regulation of potassium ion export across plasma membrane(GO:1903764) regulation of membrane repolarization during ventricular cardiac muscle cell action potential(GO:1905024)
0.1 0.4 GO:0050861 positive regulation of B cell receptor signaling pathway(GO:0050861)
0.1 0.4 GO:0071596 ubiquitin-dependent protein catabolic process via the N-end rule pathway(GO:0071596)
0.1 0.9 GO:0071578 zinc II ion transmembrane import(GO:0071578)
0.1 7.1 GO:0050885 neuromuscular process controlling balance(GO:0050885)
0.1 0.1 GO:0061535 glutamate secretion, neurotransmission(GO:0061535)
0.1 0.3 GO:0050775 positive regulation of dendrite morphogenesis(GO:0050775)
0.1 1.3 GO:0047497 establishment of mitochondrion localization, microtubule-mediated(GO:0034643) mitochondrion transport along microtubule(GO:0047497)
0.1 0.6 GO:0031424 keratinization(GO:0031424)
0.1 0.4 GO:0001922 B-1 B cell homeostasis(GO:0001922)
0.1 0.8 GO:0090084 negative regulation of inclusion body assembly(GO:0090084)
0.1 0.8 GO:0006622 protein targeting to lysosome(GO:0006622)
0.1 1.0 GO:2000463 positive regulation of excitatory postsynaptic potential(GO:2000463)
0.1 1.2 GO:0010954 positive regulation of protein processing(GO:0010954)
0.1 0.2 GO:0072385 minus-end-directed organelle transport along microtubule(GO:0072385)
0.1 2.4 GO:0018345 protein palmitoylation(GO:0018345)
0.1 0.3 GO:0010820 positive regulation of T cell chemotaxis(GO:0010820) PMA-inducible membrane protein ectodomain proteolysis(GO:0051088)
0.1 0.2 GO:1902513 regulation of organelle transport along microtubule(GO:1902513)
0.1 0.2 GO:0002329 pre-B cell differentiation(GO:0002329)
0.1 1.0 GO:0031507 heterochromatin assembly(GO:0031507)
0.1 1.2 GO:0002495 antigen processing and presentation of peptide antigen via MHC class II(GO:0002495)
0.1 3.0 GO:0048008 platelet-derived growth factor receptor signaling pathway(GO:0048008)
0.1 1.3 GO:0006182 cGMP biosynthetic process(GO:0006182)
0.1 0.8 GO:1903301 positive regulation of glucokinase activity(GO:0033133) positive regulation of hexokinase activity(GO:1903301)
0.1 0.3 GO:0008300 isoprenoid catabolic process(GO:0008300)
0.1 0.4 GO:1904721 regulation of mRNA cleavage(GO:0031437) negative regulation of mRNA cleavage(GO:0031438) negative regulation of immunoglobulin secretion(GO:0051025) regulation of mRNA endonucleolytic cleavage involved in unfolded protein response(GO:1904720) negative regulation of mRNA endonucleolytic cleavage involved in unfolded protein response(GO:1904721)
0.1 0.9 GO:0035988 chondrocyte proliferation(GO:0035988)
0.1 0.8 GO:0006610 ribosomal protein import into nucleus(GO:0006610)
0.1 0.8 GO:0035235 ionotropic glutamate receptor signaling pathway(GO:0035235)
0.1 0.3 GO:0034214 protein hexamerization(GO:0034214)
0.1 0.1 GO:0030321 transepithelial chloride transport(GO:0030321)
0.1 1.4 GO:0043968 histone H2A acetylation(GO:0043968)
0.1 1.2 GO:0070050 neuron cellular homeostasis(GO:0070050)
0.1 0.8 GO:0010839 negative regulation of keratinocyte proliferation(GO:0010839)
0.1 0.4 GO:0089700 protein kinase D signaling(GO:0089700)
0.1 0.1 GO:0034427 nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5'(GO:0034427)
0.1 0.2 GO:0015910 peroxisomal long-chain fatty acid import(GO:0015910)
0.1 0.5 GO:0032380 regulation of intracellular lipid transport(GO:0032377) regulation of intracellular sterol transport(GO:0032380) regulation of intracellular cholesterol transport(GO:0032383)
0.1 2.5 GO:0045746 negative regulation of Notch signaling pathway(GO:0045746)
0.1 3.1 GO:0016126 sterol biosynthetic process(GO:0016126)
0.1 0.1 GO:0009405 pathogenesis(GO:0009405)
0.1 1.7 GO:0095500 acetylcholine receptor signaling pathway(GO:0095500) signal transduction involved in cellular response to ammonium ion(GO:1903831) response to acetylcholine(GO:1905144) cellular response to acetylcholine(GO:1905145)
0.1 0.5 GO:0045109 intermediate filament organization(GO:0045109)
0.1 0.9 GO:0055013 cardiac muscle cell development(GO:0055013)
0.1 0.2 GO:0021852 pyramidal neuron migration(GO:0021852)
0.1 0.7 GO:2000310 regulation of N-methyl-D-aspartate selective glutamate receptor activity(GO:2000310)
0.1 0.6 GO:0016925 protein sumoylation(GO:0016925)
0.1 0.4 GO:0042795 snRNA transcription from RNA polymerase II promoter(GO:0042795)
0.1 0.6 GO:0060510 Type II pneumocyte differentiation(GO:0060510)
0.1 1.5 GO:0010738 regulation of protein kinase A signaling(GO:0010738)
0.1 0.7 GO:0016322 neuron remodeling(GO:0016322)
0.1 0.4 GO:0007296 vitellogenesis(GO:0007296)
0.1 0.1 GO:2000630 positive regulation of miRNA metabolic process(GO:2000630)
0.1 0.1 GO:0051305 meiotic chromosome movement towards spindle pole(GO:0016344) chromosome movement towards spindle pole(GO:0051305)
0.1 0.4 GO:0018401 peptidyl-proline hydroxylation to 4-hydroxy-L-proline(GO:0018401)
0.1 1.8 GO:0060078 regulation of postsynaptic membrane potential(GO:0060078)
0.1 1.6 GO:0008333 endosome to lysosome transport(GO:0008333)
0.1 0.7 GO:0007176 regulation of epidermal growth factor-activated receptor activity(GO:0007176)
0.1 1.2 GO:0051764 actin crosslink formation(GO:0051764)
0.1 2.3 GO:0006891 intra-Golgi vesicle-mediated transport(GO:0006891)
0.1 1.3 GO:0001706 endoderm formation(GO:0001706)
0.1 0.9 GO:0051205 protein insertion into membrane(GO:0051205)
0.1 0.8 GO:0090161 Golgi ribbon formation(GO:0090161)
0.1 0.6 GO:0045723 positive regulation of fatty acid biosynthetic process(GO:0045723)
0.1 0.2 GO:0045976 negative regulation of mitotic cell cycle, embryonic(GO:0045976)
0.1 0.8 GO:0051292 nuclear pore complex assembly(GO:0051292)
0.1 0.4 GO:0032020 ISG15-protein conjugation(GO:0032020)
0.1 0.2 GO:0060214 stem cell fate specification(GO:0048866) endocardium formation(GO:0060214)
0.1 0.4 GO:0038028 insulin receptor signaling pathway via phosphatidylinositol 3-kinase(GO:0038028)
0.1 0.4 GO:0030539 male genitalia development(GO:0030539)
0.1 0.2 GO:0044339 canonical Wnt signaling pathway involved in osteoblast differentiation(GO:0044339)
0.1 0.3 GO:0006013 mannose metabolic process(GO:0006013)
0.1 0.3 GO:0051901 positive regulation of mitochondrial depolarization(GO:0051901)
0.1 0.3 GO:2000491 positive regulation of hepatic stellate cell activation(GO:2000491)
0.1 0.2 GO:0042560 10-formyltetrahydrofolate catabolic process(GO:0009258) folic acid-containing compound catabolic process(GO:0009397) pteridine-containing compound catabolic process(GO:0042560)
0.1 0.3 GO:0045713 low-density lipoprotein particle receptor biosynthetic process(GO:0045713) regulation of low-density lipoprotein particle receptor biosynthetic process(GO:0045714)
0.1 0.6 GO:0070932 histone H3 deacetylation(GO:0070932)
0.1 1.2 GO:0046513 ceramide biosynthetic process(GO:0046513)
0.1 0.2 GO:1901165 positive regulation of trophoblast cell migration(GO:1901165)
0.1 0.3 GO:0060052 neurofilament cytoskeleton organization(GO:0060052)
0.0 0.1 GO:0086048 membrane depolarization during bundle of His cell action potential(GO:0086048) positive regulation of high voltage-gated calcium channel activity(GO:1901843)
0.0 2.2 GO:0030968 endoplasmic reticulum unfolded protein response(GO:0030968)
0.0 0.3 GO:0001990 regulation of systemic arterial blood pressure by hormone(GO:0001990)
0.0 0.4 GO:0006398 mRNA 3'-end processing by stem-loop binding and cleavage(GO:0006398)
0.0 0.8 GO:0046856 phosphatidylinositol dephosphorylation(GO:0046856)
0.0 0.1 GO:0007250 activation of NF-kappaB-inducing kinase activity(GO:0007250)
0.0 0.3 GO:1990253 cellular response to leucine starvation(GO:1990253)
0.0 0.2 GO:0015692 vanadium ion transport(GO:0015676) lead ion transport(GO:0015692)
0.0 0.5 GO:0007616 long-term memory(GO:0007616)
0.0 0.6 GO:0032801 receptor catabolic process(GO:0032801)
0.0 0.2 GO:0051562 negative regulation of mitochondrial calcium ion concentration(GO:0051562)
0.0 1.8 GO:0015914 phospholipid transport(GO:0015914)
0.0 0.0 GO:0042713 sperm ejaculation(GO:0042713)
0.0 0.2 GO:0045607 regulation of auditory receptor cell differentiation(GO:0045607) regulation of mechanoreceptor differentiation(GO:0045631) regulation of inner ear receptor cell differentiation(GO:2000980)
0.0 0.2 GO:0042756 drinking behavior(GO:0042756)
0.0 0.3 GO:0021891 olfactory bulb interneuron development(GO:0021891)
0.0 0.7 GO:0006677 glycosylceramide metabolic process(GO:0006677)
0.0 0.1 GO:0046032 ADP catabolic process(GO:0046032)
0.0 0.2 GO:0060709 glycogen cell differentiation involved in embryonic placenta development(GO:0060709)
0.0 0.2 GO:0003350 pulmonary myocardium development(GO:0003350)
0.0 0.4 GO:2000272 negative regulation of receptor activity(GO:2000272)
0.0 0.2 GO:0015014 heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0015014)
0.0 0.7 GO:0046621 negative regulation of organ growth(GO:0046621)
0.0 0.3 GO:0060355 positive regulation of cell adhesion molecule production(GO:0060355)
0.0 0.2 GO:0046519 sphingoid metabolic process(GO:0046519)
0.0 0.3 GO:0045921 positive regulation of exocytosis(GO:0045921)
0.0 0.2 GO:0019509 L-methionine biosynthetic process from methylthioadenosine(GO:0019509)
0.0 0.2 GO:0007183 SMAD protein complex assembly(GO:0007183)
0.0 0.3 GO:0071340 skeletal muscle acetylcholine-gated channel clustering(GO:0071340)
0.0 0.7 GO:0030818 negative regulation of cyclic nucleotide biosynthetic process(GO:0030803) negative regulation of cAMP biosynthetic process(GO:0030818)
0.0 0.2 GO:0035616 histone H2B conserved C-terminal lysine deubiquitination(GO:0035616)
0.0 0.4 GO:0010216 maintenance of DNA methylation(GO:0010216)
0.0 0.2 GO:0060575 intestinal epithelial cell differentiation(GO:0060575)
0.0 0.2 GO:0010804 negative regulation of tumor necrosis factor-mediated signaling pathway(GO:0010804)
0.0 0.6 GO:0032958 inositol phosphate biosynthetic process(GO:0032958)
0.0 0.2 GO:0097484 dendrite extension(GO:0097484)
0.0 0.1 GO:2000053 Wnt signaling pathway involved in dorsal/ventral axis specification(GO:0044332) regulation of Wnt signaling pathway involved in dorsal/ventral axis specification(GO:2000053)
0.0 0.1 GO:0048631 skeletal muscle tissue growth(GO:0048630) regulation of skeletal muscle tissue growth(GO:0048631)
0.0 0.1 GO:0031339 negative regulation of vesicle fusion(GO:0031339)
0.0 0.6 GO:0033344 cholesterol efflux(GO:0033344)
0.0 4.9 GO:0008654 phospholipid biosynthetic process(GO:0008654)
0.0 0.7 GO:0061001 regulation of dendritic spine morphogenesis(GO:0061001)
0.0 1.5 GO:0007416 synapse assembly(GO:0007416)
0.0 0.2 GO:1902036 regulation of hematopoietic stem cell differentiation(GO:1902036)
0.0 0.3 GO:1900113 negative regulation of histone H3-K9 trimethylation(GO:1900113)
0.0 0.2 GO:0051013 microtubule severing(GO:0051013)
0.0 0.5 GO:0002028 regulation of sodium ion transport(GO:0002028)
0.0 0.2 GO:0031937 positive regulation of chromatin silencing(GO:0031937)
0.0 0.1 GO:0048672 positive regulation of collateral sprouting(GO:0048672)
0.0 0.4 GO:0034067 protein localization to Golgi apparatus(GO:0034067)
0.0 0.7 GO:0000413 protein peptidyl-prolyl isomerization(GO:0000413)
0.0 0.5 GO:0051703 social behavior(GO:0035176) intraspecies interaction between organisms(GO:0051703)
0.0 0.1 GO:1903566 positive regulation of protein localization to cilium(GO:1903566)
0.0 0.7 GO:0008542 visual learning(GO:0008542)
0.0 0.2 GO:0036265 RNA (guanine-N7)-methylation(GO:0036265)
0.0 0.5 GO:0033622 integrin activation(GO:0033622)
0.0 0.1 GO:0072321 chaperone-mediated protein transport(GO:0072321)
0.0 1.2 GO:0030490 maturation of SSU-rRNA(GO:0030490)
0.0 1.5 GO:0072583 clathrin-mediated endocytosis(GO:0072583)
0.0 0.4 GO:0032525 somite rostral/caudal axis specification(GO:0032525)
0.0 0.6 GO:0043113 receptor clustering(GO:0043113)
0.0 0.4 GO:0007193 adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway(GO:0007193)
0.0 0.1 GO:2000850 negative regulation of corticosteroid hormone secretion(GO:2000847) negative regulation of glucocorticoid secretion(GO:2000850)
0.0 0.1 GO:0002710 negative regulation of T cell mediated immunity(GO:0002710)
0.0 0.1 GO:2000642 negative regulation of early endosome to late endosome transport(GO:2000642)
0.0 0.1 GO:0044208 AMP biosynthetic process(GO:0006167) 'de novo' AMP biosynthetic process(GO:0044208)
0.0 0.1 GO:0045359 positive regulation of interferon-beta biosynthetic process(GO:0045359)
0.0 0.2 GO:2001241 positive regulation of extrinsic apoptotic signaling pathway in absence of ligand(GO:2001241)
0.0 0.6 GO:0030199 collagen fibril organization(GO:0030199)
0.0 0.3 GO:0045722 positive regulation of gluconeogenesis(GO:0045722)
0.0 0.3 GO:0021535 cell migration in hindbrain(GO:0021535)
0.0 0.3 GO:0015858 nucleoside transport(GO:0015858)
0.0 0.3 GO:0034389 lipid particle organization(GO:0034389)
0.0 0.4 GO:0021860 pyramidal neuron development(GO:0021860)
0.0 0.1 GO:0090666 scaRNA localization to Cajal body(GO:0090666)
0.0 0.2 GO:0046339 diacylglycerol metabolic process(GO:0046339)
0.0 0.4 GO:0006044 N-acetylglucosamine metabolic process(GO:0006044)
0.0 0.3 GO:0034497 protein localization to pre-autophagosomal structure(GO:0034497)
0.0 0.8 GO:0071277 cellular response to calcium ion(GO:0071277)
0.0 0.4 GO:0015693 magnesium ion transport(GO:0015693)
0.0 0.3 GO:0001829 trophectodermal cell differentiation(GO:0001829)
0.0 0.2 GO:0071260 cellular response to mechanical stimulus(GO:0071260)
0.0 0.2 GO:0002098 tRNA wobble uridine modification(GO:0002098) I-kappaB phosphorylation(GO:0007252)
0.0 0.1 GO:0006384 transcription initiation from RNA polymerase III promoter(GO:0006384)
0.0 0.5 GO:0045838 positive regulation of membrane potential(GO:0045838)
0.0 0.3 GO:0035024 negative regulation of Rho protein signal transduction(GO:0035024)
0.0 1.8 GO:0098656 anion transmembrane transport(GO:0098656)
0.0 0.1 GO:0051030 snRNA transport(GO:0051030)
0.0 0.4 GO:2000001 regulation of DNA damage checkpoint(GO:2000001)
0.0 0.3 GO:0000338 protein deneddylation(GO:0000338)
0.0 0.2 GO:2000311 regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity(GO:2000311)
0.0 0.2 GO:0044804 nucleophagy(GO:0044804)
0.0 4.2 GO:0006914 autophagy(GO:0006914)
0.0 0.1 GO:0007212 dopamine receptor signaling pathway(GO:0007212)
0.0 0.5 GO:0032011 ARF protein signal transduction(GO:0032011) regulation of ARF protein signal transduction(GO:0032012)
0.0 0.0 GO:0090136 epithelial cell-cell adhesion(GO:0090136)
0.0 0.4 GO:0071353 cellular response to interleukin-4(GO:0071353)
0.0 0.3 GO:0051382 kinetochore assembly(GO:0051382)
0.0 0.1 GO:0006172 ADP biosynthetic process(GO:0006172)
0.0 0.2 GO:0002446 neutrophil mediated immunity(GO:0002446)
0.0 0.0 GO:0033615 mitochondrial proton-transporting ATP synthase complex assembly(GO:0033615)
0.0 0.2 GO:0022617 extracellular matrix disassembly(GO:0022617)
0.0 0.7 GO:0046785 microtubule polymerization(GO:0046785)
0.0 0.2 GO:0001782 B cell homeostasis(GO:0001782)
0.0 0.2 GO:0002021 response to dietary excess(GO:0002021)
0.0 0.2 GO:0006415 translational termination(GO:0006415)
0.0 0.8 GO:0030641 regulation of cellular pH(GO:0030641)
0.0 0.2 GO:0071218 cellular response to misfolded protein(GO:0071218)
0.0 0.3 GO:0050919 negative chemotaxis(GO:0050919)
0.0 0.1 GO:0018095 protein polyglutamylation(GO:0018095)
0.0 0.4 GO:0046034 ATP metabolic process(GO:0046034)
0.0 0.2 GO:0016075 rRNA catabolic process(GO:0016075)
0.0 0.3 GO:0006487 protein N-linked glycosylation(GO:0006487)
0.0 0.0 GO:0042359 vitamin D metabolic process(GO:0042359)
0.0 0.0 GO:0006369 termination of RNA polymerase II transcription(GO:0006369)
0.0 0.0 GO:0014005 microglia differentiation(GO:0014004) microglia development(GO:0014005)
0.0 0.0 GO:0060423 foregut regionalization(GO:0060423) lung field specification(GO:0060424) lung induction(GO:0060492) regulation of branching involved in lung morphogenesis(GO:0061046) positive regulation of branching involved in lung morphogenesis(GO:0061047)
0.0 0.0 GO:0045945 positive regulation of transcription from RNA polymerase III promoter(GO:0045945)
0.0 0.1 GO:0060670 branching involved in labyrinthine layer morphogenesis(GO:0060670)
0.0 0.4 GO:0015807 L-amino acid transport(GO:0015807)
0.0 0.1 GO:0010457 centriole-centriole cohesion(GO:0010457)
0.0 0.2 GO:0016601 Rac protein signal transduction(GO:0016601)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
2.2 6.7 GO:0098855 HCN channel complex(GO:0098855)
1.5 4.6 GO:0097058 CRLF-CLCF1 complex(GO:0097058)
1.2 3.6 GO:0072534 perineuronal net(GO:0072534)
0.8 2.3 GO:1903095 microprocessor complex(GO:0070877) ribonuclease III complex(GO:1903095)
0.8 3.8 GO:0038039 G-protein coupled receptor heterodimeric complex(GO:0038039)
0.7 3.4 GO:0009331 glycerol-3-phosphate dehydrogenase complex(GO:0009331)
0.7 3.4 GO:0005587 collagen type IV trimer(GO:0005587) network-forming collagen trimer(GO:0098642) collagen network(GO:0098645) basement membrane collagen trimer(GO:0098651)
0.6 1.8 GO:0016533 cyclin-dependent protein kinase 5 holoenzyme complex(GO:0016533)
0.6 2.8 GO:1990761 growth cone lamellipodium(GO:1990761)
0.5 2.6 GO:0032437 cuticular plate(GO:0032437)
0.4 2.7 GO:0097513 myosin II filament(GO:0097513)
0.4 1.6 GO:1902937 inward rectifier potassium channel complex(GO:1902937)
0.4 7.3 GO:0008074 guanylate cyclase complex, soluble(GO:0008074)
0.4 3.4 GO:1990454 L-type voltage-gated calcium channel complex(GO:1990454)
0.3 1.4 GO:0031673 H zone(GO:0031673)
0.3 1.3 GO:0070032 synaptobrevin 2-SNAP-25-syntaxin-1a-complexin I complex(GO:0070032) synaptobrevin 2-SNAP-25-syntaxin-1a-complexin II complex(GO:0070033)
0.3 4.2 GO:0043205 microfibril(GO:0001527) fibril(GO:0043205)
0.3 1.9 GO:0016035 zeta DNA polymerase complex(GO:0016035)
0.3 1.5 GO:1990604 IRE1-TRAF2-ASK1 complex(GO:1990604)
0.3 1.4 GO:0001533 cornified envelope(GO:0001533)
0.3 8.5 GO:0005891 voltage-gated calcium channel complex(GO:0005891)
0.3 2.0 GO:0033391 chromatoid body(GO:0033391)
0.3 2.0 GO:0097433 dense body(GO:0097433)
0.2 2.0 GO:0032009 early phagosome(GO:0032009)
0.2 3.1 GO:0070852 cell body fiber(GO:0070852)
0.2 0.7 GO:0097233 lamellar body membrane(GO:0097232) alveolar lamellar body membrane(GO:0097233)
0.2 1.7 GO:0048787 presynaptic active zone membrane(GO:0048787)
0.2 3.8 GO:1990635 proximal dendrite(GO:1990635)
0.2 3.7 GO:0042101 T cell receptor complex(GO:0042101)
0.2 0.8 GO:0043564 Ku70:Ku80 complex(GO:0043564)
0.2 1.2 GO:0000322 storage vacuole(GO:0000322)
0.2 8.2 GO:0032809 neuronal cell body membrane(GO:0032809)
0.2 1.4 GO:0005655 nucleolar ribonuclease P complex(GO:0005655)
0.2 0.8 GO:0099569 presynaptic cytoskeleton(GO:0099569)
0.2 0.9 GO:0005968 Rab-protein geranylgeranyltransferase complex(GO:0005968)
0.2 2.6 GO:0000145 exocyst(GO:0000145)
0.2 0.7 GO:0032444 activin responsive factor complex(GO:0032444)
0.2 1.8 GO:0030130 clathrin coat of trans-Golgi network vesicle(GO:0030130)
0.2 0.4 GO:0098888 extrinsic component of presynaptic membrane(GO:0098888)
0.2 11.0 GO:0009925 basal plasma membrane(GO:0009925)
0.2 5.7 GO:0051233 spindle midzone(GO:0051233)
0.2 0.9 GO:0044437 vacuolar membrane(GO:0005774) vacuolar part(GO:0044437)
0.2 1.2 GO:0098554 cytoplasmic side of endoplasmic reticulum membrane(GO:0098554)
0.2 0.5 GO:1990682 CSF1-CSF1R complex(GO:1990682)
0.2 1.7 GO:0000812 Swr1 complex(GO:0000812)
0.2 0.6 GO:0036449 microtubule minus-end(GO:0036449)
0.2 0.8 GO:0044611 nuclear pore inner ring(GO:0044611)
0.1 0.4 GO:0031313 extrinsic component of endosome membrane(GO:0031313)
0.1 0.9 GO:0031314 extrinsic component of mitochondrial inner membrane(GO:0031314)
0.1 0.1 GO:1904949 ATPase complex(GO:1904949)
0.1 1.4 GO:0008290 F-actin capping protein complex(GO:0008290)
0.1 1.2 GO:0031594 neuromuscular junction(GO:0031594)
0.1 2.2 GO:0005884 actin filament(GO:0005884)
0.1 1.5 GO:0042582 primary lysosome(GO:0005766) azurophil granule(GO:0042582)
0.1 1.2 GO:0036056 filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057)
0.1 1.0 GO:0030132 clathrin coat of coated pit(GO:0030132)
0.1 5.7 GO:0030173 integral component of Golgi membrane(GO:0030173)
0.1 1.8 GO:0001518 voltage-gated sodium channel complex(GO:0001518)
0.1 4.1 GO:0032281 AMPA glutamate receptor complex(GO:0032281)
0.1 1.1 GO:0014731 spectrin-associated cytoskeleton(GO:0014731)
0.1 1.2 GO:0035068 micro-ribonucleoprotein complex(GO:0035068)
0.1 8.2 GO:0008076 voltage-gated potassium channel complex(GO:0008076)
0.1 0.4 GO:0044326 dendritic spine neck(GO:0044326)
0.1 0.8 GO:0005827 polar microtubule(GO:0005827)
0.1 0.8 GO:0044352 pinosome(GO:0044352) macropinosome(GO:0044354)
0.1 2.4 GO:0097038 perinuclear endoplasmic reticulum(GO:0097038)
0.1 0.5 GO:0097226 sperm mitochondrial sheath(GO:0097226)
0.1 5.5 GO:0031901 early endosome membrane(GO:0031901)
0.1 0.3 GO:0005773 vacuole(GO:0005773)
0.1 1.4 GO:0032580 Golgi cisterna membrane(GO:0032580)
0.1 0.9 GO:0032300 mismatch repair complex(GO:0032300)
0.1 0.4 GO:0016222 procollagen-proline 4-dioxygenase complex(GO:0016222)
0.1 0.3 GO:0043541 UDP-N-acetylglucosamine transferase complex(GO:0043541)
0.1 3.6 GO:0048786 presynaptic active zone(GO:0048786)
0.1 1.6 GO:0031588 nucleotide-activated protein kinase complex(GO:0031588)
0.1 1.1 GO:0005923 bicellular tight junction(GO:0005923) occluding junction(GO:0070160)
0.1 0.8 GO:0032937 SREBP-SCAP-Insig complex(GO:0032937)
0.1 30.4 GO:0060076 excitatory synapse(GO:0060076)
0.1 0.8 GO:0097427 microtubule bundle(GO:0097427)
0.1 1.1 GO:0032590 dendrite membrane(GO:0032590)
0.1 0.3 GO:0034657 GID complex(GO:0034657)
0.1 1.1 GO:0030140 trans-Golgi network transport vesicle(GO:0030140)
0.1 1.1 GO:0035631 CD40 receptor complex(GO:0035631)
0.1 0.9 GO:0005677 chromatin silencing complex(GO:0005677)
0.1 0.6 GO:0030128 clathrin coat of endocytic vesicle(GO:0030128) clathrin-coated endocytic vesicle membrane(GO:0030669)
0.1 17.3 GO:0000139 Golgi membrane(GO:0000139)
0.1 0.9 GO:0030427 site of polarized growth(GO:0030427)
0.1 1.4 GO:0042734 presynaptic membrane(GO:0042734)
0.1 1.6 GO:0030659 cytoplasmic vesicle membrane(GO:0030659)
0.1 1.2 GO:0016581 NuRD complex(GO:0016581) CHD-type complex(GO:0090545)
0.1 0.1 GO:0031310 integral component of vacuolar membrane(GO:0031166) intrinsic component of vacuolar membrane(GO:0031310)
0.1 0.1 GO:0030134 ER to Golgi transport vesicle(GO:0030134)
0.1 1.6 GO:0071782 endoplasmic reticulum tubular network(GO:0071782)
0.1 0.2 GO:0048179 activin receptor complex(GO:0048179)
0.1 1.4 GO:0005942 phosphatidylinositol 3-kinase complex(GO:0005942)
0.1 0.4 GO:0034388 Pwp2p-containing subcomplex of 90S preribosome(GO:0034388)
0.1 0.6 GO:0030057 desmosome(GO:0030057)
0.1 0.4 GO:0033263 CORVET complex(GO:0033263)
0.1 0.4 GO:0070847 core mediator complex(GO:0070847)
0.1 1.5 GO:0055038 recycling endosome membrane(GO:0055038)
0.1 0.4 GO:0044233 ER-mitochondrion membrane contact site(GO:0044233)
0.1 0.3 GO:0005883 neurofilament(GO:0005883)
0.1 0.1 GO:0044194 cytolytic granule(GO:0044194)
0.1 0.4 GO:0005638 lamin filament(GO:0005638)
0.1 1.6 GO:0031201 SNARE complex(GO:0031201)
0.1 2.4 GO:0005876 spindle microtubule(GO:0005876)
0.1 0.3 GO:0005683 U7 snRNP(GO:0005683)
0.1 0.9 GO:0036038 MKS complex(GO:0036038)
0.1 0.5 GO:0042587 glycogen granule(GO:0042587)
0.1 2.1 GO:0030136 clathrin-coated vesicle(GO:0030136)
0.1 0.6 GO:0031209 SCAR complex(GO:0031209)
0.1 1.9 GO:0045335 phagocytic vesicle(GO:0045335)
0.1 4.4 GO:0034702 ion channel complex(GO:0034702)
0.1 0.3 GO:0005853 eukaryotic translation elongation factor 1 complex(GO:0005853)
0.0 0.3 GO:0005796 Golgi lumen(GO:0005796)
0.0 0.3 GO:0002177 manchette(GO:0002177)
0.0 0.4 GO:0031464 Cul4A-RING E3 ubiquitin ligase complex(GO:0031464)
0.0 0.1 GO:0055087 Ski complex(GO:0055087)
0.0 0.5 GO:0005915 zonula adherens(GO:0005915)
0.0 0.2 GO:0070826 paraferritin complex(GO:0070826)
0.0 1.2 GO:0036126 sperm flagellum(GO:0036126)
0.0 0.4 GO:0071598 neuronal ribonucleoprotein granule(GO:0071598)
0.0 0.5 GO:0044754 secondary lysosome(GO:0005767) autolysosome(GO:0044754)
0.0 3.5 GO:0005604 basement membrane(GO:0005604)
0.0 0.6 GO:0000930 gamma-tubulin complex(GO:0000930)
0.0 1.0 GO:0035869 ciliary transition zone(GO:0035869)
0.0 1.3 GO:0005643 nuclear pore(GO:0005643)
0.0 0.2 GO:0043527 tRNA methyltransferase complex(GO:0043527)
0.0 0.8 GO:0005665 DNA-directed RNA polymerase II, core complex(GO:0005665)
0.0 0.6 GO:0030027 lamellipodium(GO:0030027)
0.0 0.1 GO:0070436 Grb2-EGFR complex(GO:0070436)
0.0 2.4 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.0 4.8 GO:0070382 exocytic vesicle(GO:0070382)
0.0 0.5 GO:0031045 dense core granule(GO:0031045)
0.0 0.1 GO:0030891 VCB complex(GO:0030891)
0.0 0.1 GO:0043020 NADPH oxidase complex(GO:0043020)
0.0 0.5 GO:0031932 TORC2 complex(GO:0031932)
0.0 0.3 GO:0005798 Golgi-associated vesicle(GO:0005798)
0.0 0.3 GO:0031235 intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235)
0.0 2.0 GO:0005811 lipid particle(GO:0005811)
0.0 0.4 GO:0016589 NURF complex(GO:0016589)
0.0 0.6 GO:0032040 small-subunit processome(GO:0032040)
0.0 0.5 GO:0035102 PRC1 complex(GO:0035102)
0.0 0.8 GO:0002102 podosome(GO:0002102)
0.0 0.6 GO:0080008 Cul4-RING E3 ubiquitin ligase complex(GO:0080008)
0.0 0.2 GO:0005642 annulate lamellae(GO:0005642)
0.0 0.6 GO:0019898 extrinsic component of membrane(GO:0019898)
0.0 0.7 GO:0071565 nBAF complex(GO:0071565)
0.0 10.0 GO:0030425 dendrite(GO:0030425)
0.0 0.5 GO:0005732 small nucleolar ribonucleoprotein complex(GO:0005732)
0.0 2.1 GO:0031234 extrinsic component of cytoplasmic side of plasma membrane(GO:0031234)
0.0 0.8 GO:0015030 Cajal body(GO:0015030)
0.0 0.2 GO:0045252 oxoglutarate dehydrogenase complex(GO:0045252)
0.0 0.6 GO:0005921 gap junction(GO:0005921)
0.0 1.1 GO:0005776 autophagosome(GO:0005776)
0.0 0.1 GO:0042719 mitochondrial intermembrane space protein transporter complex(GO:0042719)
0.0 0.4 GO:0005852 eukaryotic translation initiation factor 3 complex(GO:0005852)
0.0 0.4 GO:0032420 stereocilium(GO:0032420)
0.0 0.1 GO:0016281 eukaryotic translation initiation factor 4F complex(GO:0016281)
0.0 0.3 GO:0042555 MCM complex(GO:0042555)
0.0 0.4 GO:0030315 T-tubule(GO:0030315)
0.0 0.8 GO:0043679 axon terminus(GO:0043679)
0.0 0.2 GO:0034518 mRNA cap binding complex(GO:0005845) RNA cap binding complex(GO:0034518)
0.0 1.3 GO:0045211 postsynaptic membrane(GO:0045211)
0.0 0.5 GO:0016235 aggresome(GO:0016235)
0.0 1.4 GO:0005903 brush border(GO:0005903)
0.0 0.9 GO:0005758 mitochondrial intermembrane space(GO:0005758)
0.0 0.1 GO:0005965 protein farnesyltransferase complex(GO:0005965)
0.0 0.2 GO:0000124 SAGA complex(GO:0000124)
0.0 0.2 GO:0012507 ER to Golgi transport vesicle membrane(GO:0012507) COPII vesicle coat(GO:0030127)
0.0 0.1 GO:0000940 condensed chromosome outer kinetochore(GO:0000940)
0.0 0.2 GO:0005666 DNA-directed RNA polymerase III complex(GO:0005666)
0.0 47.3 GO:0016021 integral component of membrane(GO:0016021)
0.0 0.6 GO:0005788 endoplasmic reticulum lumen(GO:0005788)
0.0 0.4 GO:0071339 MLL1/2 complex(GO:0044665) MLL1 complex(GO:0071339)
0.0 4.2 GO:0048471 perinuclear region of cytoplasm(GO:0048471)
0.0 0.9 GO:0042641 actomyosin(GO:0042641)
0.0 0.1 GO:0097165 nuclear stress granule(GO:0097165)
0.0 1.7 GO:0031965 nuclear membrane(GO:0031965)
0.0 0.1 GO:0030015 CCR4-NOT core complex(GO:0030015)
0.0 0.5 GO:0008023 transcription elongation factor complex(GO:0008023)
0.0 0.1 GO:0005832 chaperonin-containing T-complex(GO:0005832)
0.0 0.7 GO:0005769 early endosome(GO:0005769)
0.0 0.1 GO:0017119 Golgi transport complex(GO:0017119)
0.0 0.2 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.0 0.6 GO:0098852 lysosomal membrane(GO:0005765) lytic vacuole membrane(GO:0098852)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
2.3 9.3 GO:0005008 hepatocyte growth factor-activated receptor activity(GO:0005008)
1.7 6.7 GO:0005222 intracellular cAMP activated cation channel activity(GO:0005222)
1.2 3.6 GO:0030158 protein xylosyltransferase activity(GO:0030158)
1.2 7.0 GO:0015018 galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase activity(GO:0015018)
1.1 3.4 GO:0016015 morphogen activity(GO:0016015)
1.0 6.0 GO:0008294 calcium- and calmodulin-responsive adenylate cyclase activity(GO:0008294)
0.9 6.3 GO:0005127 ciliary neurotrophic factor receptor binding(GO:0005127)
0.9 4.4 GO:0005030 neurotrophin receptor activity(GO:0005030)
0.8 2.4 GO:0016964 alpha-2 macroglobulin receptor activity(GO:0016964)
0.8 2.3 GO:0031826 type 2A serotonin receptor binding(GO:0031826)
0.8 4.5 GO:0005042 netrin receptor activity(GO:0005042)
0.7 2.2 GO:0008515 sucrose:proton symporter activity(GO:0008506) sucrose transmembrane transporter activity(GO:0008515) disaccharide transmembrane transporter activity(GO:0015154) oligosaccharide transmembrane transporter activity(GO:0015157)
0.7 2.9 GO:0017095 heparan sulfate 6-O-sulfotransferase activity(GO:0017095)
0.7 3.4 GO:0004367 glycerol-3-phosphate dehydrogenase [NAD+] activity(GO:0004367)
0.7 3.9 GO:0005173 stem cell factor receptor binding(GO:0005173)
0.6 3.8 GO:0004965 G-protein coupled GABA receptor activity(GO:0004965)
0.6 1.8 GO:0003989 acetyl-CoA carboxylase activity(GO:0003989)
0.5 4.9 GO:0005007 fibroblast growth factor-activated receptor activity(GO:0005007)
0.5 4.9 GO:0004571 mannosyl-oligosaccharide 1,2-alpha-mannosidase activity(GO:0004571)
0.5 2.1 GO:0003976 UDP-N-acetylglucosamine-lysosomal-enzyme N-acetylglucosaminephosphotransferase activity(GO:0003976)
0.5 1.5 GO:0070890 L-ascorbate:sodium symporter activity(GO:0008520) L-ascorbic acid transporter activity(GO:0015229) sodium-dependent L-ascorbate transmembrane transporter activity(GO:0070890)
0.5 3.4 GO:0086007 voltage-gated calcium channel activity involved in cardiac muscle cell action potential(GO:0086007)
0.5 1.5 GO:0004517 nitric-oxide synthase activity(GO:0004517)
0.5 7.2 GO:0031210 phosphatidylcholine binding(GO:0031210)
0.5 3.3 GO:0032184 SUMO polymer binding(GO:0032184)
0.5 1.4 GO:0046624 sphingolipid transporter activity(GO:0046624)
0.4 0.9 GO:0015924 mannosyl-oligosaccharide mannosidase activity(GO:0015924)
0.4 2.2 GO:0004525 ribonuclease III activity(GO:0004525) double-stranded RNA-specific ribonuclease activity(GO:0032296)
0.4 1.7 GO:0008332 low voltage-gated calcium channel activity(GO:0008332)
0.4 2.5 GO:0005004 GPI-linked ephrin receptor activity(GO:0005004)
0.4 1.6 GO:0004741 [pyruvate dehydrogenase (lipoamide)] phosphatase activity(GO:0004741)
0.4 1.2 GO:0016934 extracellular-glycine-gated ion channel activity(GO:0016933) extracellular-glycine-gated chloride channel activity(GO:0016934)
0.4 2.0 GO:0033188 sphingomyelin synthase activity(GO:0033188) ceramide cholinephosphotransferase activity(GO:0047493)
0.4 8.4 GO:0043274 phospholipase binding(GO:0043274)
0.4 2.9 GO:0035033 histone deacetylase regulator activity(GO:0035033)
0.4 2.5 GO:0005094 Rho GDP-dissociation inhibitor activity(GO:0005094)
0.3 1.4 GO:0001847 opsonin receptor activity(GO:0001847)
0.3 1.7 GO:0010385 double-stranded methylated DNA binding(GO:0010385)
0.3 4.7 GO:0022842 leak channel activity(GO:0022840) narrow pore channel activity(GO:0022842)
0.3 1.7 GO:0001517 N-acetylglucosamine 6-O-sulfotransferase activity(GO:0001517)
0.3 1.3 GO:0070012 oligopeptidase activity(GO:0070012)
0.3 2.6 GO:0016717 oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water(GO:0016717)
0.3 1.0 GO:0031752 D5 dopamine receptor binding(GO:0031752)
0.3 1.6 GO:0005005 transmembrane-ephrin receptor activity(GO:0005005)
0.3 0.9 GO:0034211 GTP-dependent protein kinase activity(GO:0034211)
0.3 0.9 GO:0032137 guanine/thymine mispair binding(GO:0032137) single guanine insertion binding(GO:0032142)
0.3 1.3 GO:0061628 H3K27me3 modified histone binding(GO:0061628)
0.3 0.9 GO:0016262 protein N-acetylglucosaminyltransferase activity(GO:0016262)
0.3 0.9 GO:0032052 bile acid binding(GO:0032052)
0.3 0.9 GO:0004993 G-protein coupled serotonin receptor activity(GO:0004993)
0.3 0.3 GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
0.3 2.9 GO:0005068 transmembrane receptor protein tyrosine kinase adaptor activity(GO:0005068)
0.3 0.9 GO:0016309 1-phosphatidylinositol-5-phosphate 4-kinase activity(GO:0016309)
0.3 1.1 GO:0047237 glucuronylgalactosylproteoglycan 4-beta-N-acetylgalactosaminyltransferase activity(GO:0047237)
0.3 6.0 GO:0003841 1-acylglycerol-3-phosphate O-acyltransferase activity(GO:0003841)
0.3 5.1 GO:0050811 GABA receptor binding(GO:0050811)
0.3 0.8 GO:0071209 U7 snRNA binding(GO:0071209)
0.3 4.8 GO:0005251 delayed rectifier potassium channel activity(GO:0005251)
0.3 0.8 GO:0051379 epinephrine binding(GO:0051379)
0.3 2.4 GO:0005432 calcium:sodium antiporter activity(GO:0005432)
0.3 1.8 GO:0086006 voltage-gated sodium channel activity involved in cardiac muscle cell action potential(GO:0086006)
0.3 1.0 GO:0004999 vasoactive intestinal polypeptide receptor activity(GO:0004999)
0.3 2.9 GO:0045499 chemorepellent activity(GO:0045499)
0.3 1.0 GO:0043125 ErbB-3 class receptor binding(GO:0043125)
0.2 1.0 GO:0004663 Rab geranylgeranyltransferase activity(GO:0004663)
0.2 0.7 GO:0022833 mechanically-gated ion channel activity(GO:0008381) mechanically gated channel activity(GO:0022833)
0.2 2.3 GO:0017162 aryl hydrocarbon receptor binding(GO:0017162)
0.2 2.1 GO:0030306 ADP-ribosylation factor binding(GO:0030306)
0.2 2.5 GO:0032036 myosin heavy chain binding(GO:0032036)
0.2 0.9 GO:0004706 JUN kinase kinase kinase activity(GO:0004706)
0.2 2.0 GO:0050291 sphingosine N-acyltransferase activity(GO:0050291)
0.2 1.3 GO:0004016 adenylate cyclase activity(GO:0004016)
0.2 1.1 GO:0022851 GABA-gated chloride ion channel activity(GO:0022851)
0.2 2.2 GO:0005049 nuclear export signal receptor activity(GO:0005049)
0.2 1.1 GO:0000293 ferric-chelate reductase activity(GO:0000293)
0.2 0.6 GO:0034041 lipid-transporting ATPase activity(GO:0034040) sterol-transporting ATPase activity(GO:0034041)
0.2 1.7 GO:0048495 Roundabout binding(GO:0048495)
0.2 2.7 GO:0005225 volume-sensitive anion channel activity(GO:0005225)
0.2 0.6 GO:0004605 phosphatidate cytidylyltransferase activity(GO:0004605)
0.2 2.9 GO:0017154 semaphorin receptor activity(GO:0017154)
0.2 1.0 GO:0043812 phosphatidylinositol-4-phosphate phosphatase activity(GO:0043812)
0.2 0.8 GO:0008169 C-methyltransferase activity(GO:0008169)
0.2 0.8 GO:0003726 double-stranded RNA adenosine deaminase activity(GO:0003726)
0.2 0.8 GO:0038025 reelin receptor activity(GO:0038025)
0.2 1.8 GO:0030550 acetylcholine receptor inhibitor activity(GO:0030550)
0.2 1.0 GO:0003945 N-acetyllactosamine synthase activity(GO:0003945)
0.2 1.8 GO:0032050 clathrin heavy chain binding(GO:0032050)
0.2 0.8 GO:0016230 sphingomyelin phosphodiesterase activator activity(GO:0016230)
0.2 7.0 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.2 0.8 GO:0004735 pyrroline-5-carboxylate reductase activity(GO:0004735)
0.2 1.2 GO:0070699 type II activin receptor binding(GO:0070699)
0.2 3.5 GO:0004181 metallocarboxypeptidase activity(GO:0004181)
0.2 1.5 GO:0005131 growth hormone receptor binding(GO:0005131)
0.2 2.7 GO:0030898 actin-dependent ATPase activity(GO:0030898)
0.2 2.8 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
0.2 8.2 GO:0005544 calcium-dependent phospholipid binding(GO:0005544)
0.2 0.9 GO:0035174 histone serine kinase activity(GO:0035174)
0.2 1.1 GO:0003828 alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity(GO:0003828)
0.2 6.1 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
0.2 0.9 GO:2001070 starch binding(GO:2001070)
0.2 1.4 GO:0015271 outward rectifier potassium channel activity(GO:0015271)
0.2 0.9 GO:0070330 aromatase activity(GO:0070330)
0.2 1.2 GO:0005200 structural constituent of cytoskeleton(GO:0005200)
0.2 1.6 GO:0008331 high voltage-gated calcium channel activity(GO:0008331)
0.2 0.9 GO:0030618 transforming growth factor beta receptor, pathway-specific cytoplasmic mediator activity(GO:0030618)
0.2 1.3 GO:0046934 phosphatidylinositol-4,5-bisphosphate 3-kinase activity(GO:0046934) phosphatidylinositol bisphosphate kinase activity(GO:0052813)
0.2 1.3 GO:0046790 virion binding(GO:0046790)
0.2 1.1 GO:0015129 lactate transmembrane transporter activity(GO:0015129)
0.2 0.6 GO:0034511 U3 snoRNA binding(GO:0034511)
0.2 0.9 GO:0008376 acetylgalactosaminyltransferase activity(GO:0008376)
0.2 3.3 GO:0017075 syntaxin-1 binding(GO:0017075)
0.1 0.9 GO:0070326 very-low-density lipoprotein particle receptor binding(GO:0070326)
0.1 4.7 GO:0030676 Rac guanyl-nucleotide exchange factor activity(GO:0030676)
0.1 0.7 GO:0004792 thiosulfate sulfurtransferase activity(GO:0004792)
0.1 3.0 GO:0045295 gamma-catenin binding(GO:0045295)
0.1 0.7 GO:0004305 ethanolamine kinase activity(GO:0004305)
0.1 3.2 GO:0017134 fibroblast growth factor binding(GO:0017134)
0.1 1.0 GO:0036122 BMP binding(GO:0036122)
0.1 1.0 GO:0004118 cGMP-stimulated cyclic-nucleotide phosphodiesterase activity(GO:0004118)
0.1 0.4 GO:0015232 heme transporter activity(GO:0015232)
0.1 1.1 GO:0008093 cytoskeletal adaptor activity(GO:0008093)
0.1 1.7 GO:0031005 filamin binding(GO:0031005)
0.1 1.4 GO:0019531 secondary active sulfate transmembrane transporter activity(GO:0008271) oxalate transmembrane transporter activity(GO:0019531)
0.1 3.9 GO:0070412 R-SMAD binding(GO:0070412)
0.1 3.7 GO:0008157 protein phosphatase 1 binding(GO:0008157)
0.1 0.8 GO:0015277 kainate selective glutamate receptor activity(GO:0015277)
0.1 0.5 GO:0004694 eukaryotic translation initiation factor 2alpha kinase activity(GO:0004694)
0.1 1.7 GO:0008349 MAP kinase kinase kinase kinase activity(GO:0008349)
0.1 0.4 GO:0047751 3-oxo-5-alpha-steroid 4-dehydrogenase activity(GO:0003865) steroid dehydrogenase activity, acting on the CH-CH group of donors(GO:0033765) enone reductase activity(GO:0035671) cholestenone 5-alpha-reductase activity(GO:0047751)
0.1 0.8 GO:0048407 platelet-derived growth factor binding(GO:0048407)
0.1 1.2 GO:0004526 ribonuclease P activity(GO:0004526)
0.1 1.3 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.1 0.8 GO:0001135 transcription factor activity, RNA polymerase II transcription factor recruiting(GO:0001135)
0.1 0.3 GO:0003963 RNA-3'-phosphate cyclase activity(GO:0003963)
0.1 0.7 GO:0001665 alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity(GO:0001665)
0.1 0.4 GO:0000064 L-ornithine transmembrane transporter activity(GO:0000064)
0.1 1.7 GO:0015269 calcium-activated potassium channel activity(GO:0015269)
0.1 0.3 GO:0038132 neuregulin binding(GO:0038132)
0.1 0.4 GO:0015368 calcium:cation antiporter activity(GO:0015368)
0.1 2.5 GO:0043325 phosphatidylinositol-3,4-bisphosphate binding(GO:0043325)
0.1 1.0 GO:0070411 I-SMAD binding(GO:0070411)
0.1 1.0 GO:0004890 GABA-A receptor activity(GO:0004890)
0.1 0.3 GO:0034237 protein kinase A regulatory subunit binding(GO:0034237)
0.1 0.4 GO:0008967 phosphoglycolate phosphatase activity(GO:0008967)
0.1 0.6 GO:0002135 CTP binding(GO:0002135)
0.1 0.2 GO:0061649 ubiquitinated histone binding(GO:0061649)
0.1 0.7 GO:0005519 cytoskeletal regulatory protein binding(GO:0005519)
0.1 0.8 GO:0048531 beta-1,3-galactosyltransferase activity(GO:0048531)
0.1 3.6 GO:0005249 voltage-gated potassium channel activity(GO:0005249)
0.1 0.4 GO:0003880 protein C-terminal carboxyl O-methyltransferase activity(GO:0003880)
0.1 0.5 GO:0043423 3-phosphoinositide-dependent protein kinase binding(GO:0043423)
0.1 0.7 GO:0015386 potassium:proton antiporter activity(GO:0015386)
0.1 0.4 GO:0031821 G-protein coupled serotonin receptor binding(GO:0031821)
0.1 0.8 GO:0003873 6-phosphofructo-2-kinase activity(GO:0003873) fructose-2,6-bisphosphate 2-phosphatase activity(GO:0004331)
0.1 0.4 GO:0047184 1-acylglycerophosphocholine O-acyltransferase activity(GO:0047184)
0.1 1.7 GO:0042608 T cell receptor binding(GO:0042608)
0.1 0.5 GO:0050321 tau-protein kinase activity(GO:0050321)
0.1 3.2 GO:0004683 calmodulin-dependent protein kinase activity(GO:0004683)
0.1 2.5 GO:0019707 protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)
0.1 0.4 GO:0004656 procollagen-proline 4-dioxygenase activity(GO:0004656) procollagen-proline dioxygenase activity(GO:0019798)
0.1 0.5 GO:0035381 extracellular ATP-gated cation channel activity(GO:0004931) ATP-gated ion channel activity(GO:0035381)
0.1 7.1 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.1 0.3 GO:0004559 alpha-mannosidase activity(GO:0004559)
0.1 0.4 GO:0004028 3-chloroallyl aldehyde dehydrogenase activity(GO:0004028)
0.1 0.2 GO:0004030 aldehyde dehydrogenase [NAD(P)+] activity(GO:0004030)
0.1 0.2 GO:0071936 coreceptor activity involved in Wnt signaling pathway(GO:0071936)
0.1 1.7 GO:0032183 SUMO binding(GO:0032183)
0.1 0.8 GO:0015093 ferrous iron transmembrane transporter activity(GO:0015093)
0.1 0.2 GO:0051765 inositol tetrakisphosphate kinase activity(GO:0051765)
0.1 3.2 GO:0042162 telomeric DNA binding(GO:0042162)
0.1 1.4 GO:0016709 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen(GO:0016709)
0.1 0.2 GO:0047710 bis(5'-adenosyl)-triphosphatase activity(GO:0047710)
0.1 0.4 GO:0042296 ISG15 transferase activity(GO:0042296)
0.1 1.4 GO:0005528 macrolide binding(GO:0005527) FK506 binding(GO:0005528)
0.1 0.7 GO:0008140 cAMP response element binding protein binding(GO:0008140)
0.1 1.0 GO:0005388 calcium-transporting ATPase activity(GO:0005388)
0.1 1.4 GO:0017160 Ral GTPase binding(GO:0017160)
0.1 0.5 GO:0016428 tRNA (cytosine-5-)-methyltransferase activity(GO:0016428)
0.1 0.2 GO:0008176 tRNA (guanine-N7-)-methyltransferase activity(GO:0008176)
0.1 0.3 GO:0004679 AMP-activated protein kinase activity(GO:0004679)
0.1 0.2 GO:0035650 AP-1 adaptor complex binding(GO:0035650)
0.1 0.4 GO:0008395 steroid hydroxylase activity(GO:0008395)
0.1 0.4 GO:0060698 endoribonuclease inhibitor activity(GO:0060698)
0.1 1.0 GO:0042287 MHC protein binding(GO:0042287)
0.1 0.5 GO:0016312 inositol bisphosphate phosphatase activity(GO:0016312)
0.1 1.7 GO:0043539 protein serine/threonine kinase activator activity(GO:0043539)
0.1 0.8 GO:0035325 Toll-like receptor binding(GO:0035325)
0.1 0.4 GO:0097001 ceramide binding(GO:0097001)
0.1 0.2 GO:0042289 MHC class II protein binding(GO:0042289)
0.1 0.3 GO:0008454 alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity(GO:0008454)
0.1 1.4 GO:0004012 phospholipid-translocating ATPase activity(GO:0004012)
0.1 0.2 GO:0031800 type 3 metabotropic glutamate receptor binding(GO:0031800)
0.1 0.6 GO:0032794 GTPase activating protein binding(GO:0032794)
0.1 0.2 GO:0000026 alpha-1,2-mannosyltransferase activity(GO:0000026)
0.1 1.1 GO:0004709 MAP kinase kinase kinase activity(GO:0004709)
0.1 0.8 GO:0008569 ATP-dependent microtubule motor activity, minus-end-directed(GO:0008569)
0.1 0.5 GO:0030296 protein tyrosine kinase activator activity(GO:0030296)
0.1 0.4 GO:0042500 aspartic endopeptidase activity, intramembrane cleaving(GO:0042500)
0.1 5.9 GO:0072509 divalent inorganic cation transmembrane transporter activity(GO:0072509)
0.1 0.2 GO:0005324 long-chain fatty acid transporter activity(GO:0005324)
0.1 0.3 GO:0008329 signaling pattern recognition receptor activity(GO:0008329) pattern recognition receptor activity(GO:0038187)
0.1 3.2 GO:0019894 kinesin binding(GO:0019894)
0.1 0.4 GO:0015450 P-P-bond-hydrolysis-driven protein transmembrane transporter activity(GO:0015450)
0.1 0.5 GO:0005149 interleukin-1 receptor binding(GO:0005149)
0.1 0.2 GO:0016361 activin receptor activity, type I(GO:0016361)
0.0 0.2 GO:0042328 heparan sulfate N-acetylglucosaminyltransferase activity(GO:0042328)
0.0 0.1 GO:0017116 single-stranded DNA-dependent ATP-dependent DNA helicase activity(GO:0017116)
0.0 0.2 GO:1904288 BAT3 complex binding(GO:1904288)
0.0 0.3 GO:0008607 phosphorylase kinase regulator activity(GO:0008607)
0.0 2.2 GO:0015485 cholesterol binding(GO:0015485)
0.0 0.1 GO:0015038 glutathione disulfide oxidoreductase activity(GO:0015038)
0.0 0.3 GO:0000298 endopolyphosphatase activity(GO:0000298) diphosphoinositol-polyphosphate diphosphatase activity(GO:0008486) bis(5'-adenosyl)-hexaphosphatase activity(GO:0034431) bis(5'-adenosyl)-pentaphosphatase activity(GO:0034432)
0.0 0.5 GO:0015929 hexosaminidase activity(GO:0015929)
0.0 0.0 GO:0017002 activin-activated receptor activity(GO:0017002)
0.0 0.3 GO:0034713 type I transforming growth factor beta receptor binding(GO:0034713)
0.0 1.0 GO:0050750 low-density lipoprotein particle receptor binding(GO:0050750) lipoprotein particle receptor binding(GO:0070325)
0.0 0.7 GO:0005104 fibroblast growth factor receptor binding(GO:0005104)
0.0 0.2 GO:0030292 protein tyrosine kinase inhibitor activity(GO:0030292)
0.0 0.3 GO:0035242 protein-arginine omega-N asymmetric methyltransferase activity(GO:0035242)
0.0 0.2 GO:0003836 beta-galactoside (CMP) alpha-2,3-sialyltransferase activity(GO:0003836)
0.0 0.4 GO:0051011 microtubule minus-end binding(GO:0051011)
0.0 0.4 GO:0035198 miRNA binding(GO:0035198)
0.0 0.8 GO:0017056 structural constituent of nuclear pore(GO:0017056)
0.0 0.8 GO:0015301 anion:anion antiporter activity(GO:0015301)
0.0 0.3 GO:0000182 rDNA binding(GO:0000182)
0.0 0.1 GO:0046899 nucleoside triphosphate adenylate kinase activity(GO:0046899)
0.0 0.1 GO:0004972 NMDA glutamate receptor activity(GO:0004972)
0.0 0.2 GO:0004591 oxoglutarate dehydrogenase (succinyl-transferring) activity(GO:0004591)
0.0 0.9 GO:0008139 nuclear localization sequence binding(GO:0008139)
0.0 0.1 GO:0016176 superoxide-generating NADPH oxidase activator activity(GO:0016176)
0.0 0.1 GO:0004321 fatty-acyl-CoA synthase activity(GO:0004321)
0.0 1.5 GO:0015459 potassium channel regulator activity(GO:0015459)
0.0 0.2 GO:0070008 serine-type exopeptidase activity(GO:0070008)
0.0 0.4 GO:0005545 1-phosphatidylinositol binding(GO:0005545)
0.0 1.6 GO:0016876 aminoacyl-tRNA ligase activity(GO:0004812) ligase activity, forming carbon-oxygen bonds(GO:0016875) ligase activity, forming aminoacyl-tRNA and related compounds(GO:0016876)
0.0 0.2 GO:0034452 dynactin binding(GO:0034452)
0.0 0.9 GO:0003887 DNA-directed DNA polymerase activity(GO:0003887)
0.0 0.2 GO:0000340 RNA 7-methylguanosine cap binding(GO:0000340)
0.0 0.2 GO:0004065 arylsulfatase activity(GO:0004065)
0.0 0.2 GO:0070492 oligosaccharide binding(GO:0070492)
0.0 0.5 GO:0043014 alpha-tubulin binding(GO:0043014)
0.0 0.8 GO:0001106 RNA polymerase II transcription corepressor activity(GO:0001106)
0.0 0.1 GO:0003696 satellite DNA binding(GO:0003696)
0.0 0.2 GO:0045134 uridine-diphosphatase activity(GO:0045134)
0.0 0.2 GO:0004726 non-membrane spanning protein tyrosine phosphatase activity(GO:0004726)
0.0 0.1 GO:0070740 tubulin-glutamic acid ligase activity(GO:0070740)
0.0 1.2 GO:0048306 calcium-dependent protein binding(GO:0048306)
0.0 0.6 GO:0008327 methyl-CpG binding(GO:0008327)
0.0 0.2 GO:0005540 hyaluronic acid binding(GO:0005540)
0.0 0.4 GO:0030275 LRR domain binding(GO:0030275)
0.0 0.3 GO:0033130 acetylcholine receptor binding(GO:0033130)
0.0 1.2 GO:0046875 ephrin receptor binding(GO:0046875)
0.0 0.6 GO:0071889 14-3-3 protein binding(GO:0071889)
0.0 0.7 GO:0005086 ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.0 0.2 GO:0003747 translation release factor activity(GO:0003747) translation termination factor activity(GO:0008079)
0.0 0.6 GO:0008143 poly(A) binding(GO:0008143)
0.0 6.8 GO:0005096 GTPase activator activity(GO:0005096)
0.0 0.3 GO:0080025 phosphatidylinositol-3,5-bisphosphate binding(GO:0080025)
0.0 0.2 GO:0008568 microtubule-severing ATPase activity(GO:0008568)
0.0 1.1 GO:0097110 scaffold protein binding(GO:0097110)
0.0 0.2 GO:0038191 neuropilin binding(GO:0038191)
0.0 1.8 GO:0008201 heparin binding(GO:0008201)
0.0 0.2 GO:0004143 diacylglycerol kinase activity(GO:0004143)
0.0 1.5 GO:0008083 growth factor activity(GO:0008083)
0.0 0.3 GO:1990226 histone methyltransferase binding(GO:1990226)
0.0 0.1 GO:0004920 interleukin-10 receptor activity(GO:0004920)
0.0 0.3 GO:0016290 palmitoyl-CoA hydrolase activity(GO:0016290)
0.0 0.1 GO:0016413 O-acetyltransferase activity(GO:0016413)
0.0 0.1 GO:0043262 adenosine-diphosphatase activity(GO:0043262)
0.0 0.2 GO:0002151 G-quadruplex RNA binding(GO:0002151)
0.0 0.3 GO:0005035 tumor necrosis factor-activated receptor activity(GO:0005031) death receptor activity(GO:0005035)
0.0 0.3 GO:0016864 protein disulfide isomerase activity(GO:0003756) intramolecular oxidoreductase activity, transposing S-S bonds(GO:0016864)
0.0 1.7 GO:0005516 calmodulin binding(GO:0005516)
0.0 3.2 GO:0000287 magnesium ion binding(GO:0000287)
0.0 0.5 GO:0005337 nucleoside transmembrane transporter activity(GO:0005337)
0.0 0.8 GO:0019905 syntaxin binding(GO:0019905)
0.0 0.2 GO:0001206 transcriptional repressor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001206)
0.0 0.1 GO:0015377 cation:chloride symporter activity(GO:0015377)
0.0 0.1 GO:0048406 nerve growth factor binding(GO:0048406)
0.0 0.1 GO:0070915 lysophosphatidic acid receptor activity(GO:0070915)
0.0 0.2 GO:0004659 prenyltransferase activity(GO:0004659)
0.0 0.4 GO:0004697 protein kinase C activity(GO:0004697)
0.0 0.1 GO:0009881 photoreceptor activity(GO:0009881)
0.0 0.4 GO:0001056 RNA polymerase III activity(GO:0001056)
0.0 0.5 GO:0031369 translation initiation factor binding(GO:0031369)
0.0 0.1 GO:0016846 carbon-sulfur lyase activity(GO:0016846)
0.0 0.2 GO:0016861 intramolecular oxidoreductase activity, interconverting aldoses and ketoses(GO:0016861)
0.0 0.7 GO:0015175 neutral amino acid transmembrane transporter activity(GO:0015175)
0.0 0.0 GO:0001007 transcription factor activity, core RNA polymerase III binding(GO:0000995) transcription factor activity, RNA polymerase III transcription factor binding(GO:0001007)
0.0 0.3 GO:0016854 racemase and epimerase activity(GO:0016854)
0.0 0.3 GO:0008483 transaminase activity(GO:0008483)
0.0 0.2 GO:0071855 neuropeptide receptor binding(GO:0071855)
0.0 0.0 GO:0035005 1-phosphatidylinositol-4-phosphate 3-kinase activity(GO:0035005)
0.0 0.3 GO:0005164 tumor necrosis factor receptor binding(GO:0005164)
0.0 1.2 GO:0036459 thiol-dependent ubiquitinyl hydrolase activity(GO:0036459) ubiquitinyl hydrolase activity(GO:0101005)
0.0 0.1 GO:0008432 JUN kinase binding(GO:0008432)
0.0 1.0 GO:0051082 unfolded protein binding(GO:0051082)
0.0 1.7 GO:0004930 G-protein coupled receptor activity(GO:0004930)
0.0 0.1 GO:0008545 JUN kinase kinase activity(GO:0008545)
0.0 0.4 GO:0019955 cytokine binding(GO:0019955)
0.0 0.1 GO:0008227 G-protein coupled amine receptor activity(GO:0008227)
0.0 0.4 GO:0048365 Rac GTPase binding(GO:0048365)
0.0 0.3 GO:0043027 cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027)
0.0 0.7 GO:0030165 PDZ domain binding(GO:0030165)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 1.9 ST_PAC1_RECEPTOR_PATHWAY PAC1 Receptor Pathway
0.5 8.3 PID_LPA4_PATHWAY LPA4-mediated signaling events
0.4 8.3 ST_WNT_CA2_CYCLIC_GMP_PATHWAY Wnt/Ca2+/cyclic GMP signaling.
0.3 0.3 PID_INTEGRIN4_PATHWAY Alpha6 beta4 integrin-ligand interactions
0.3 1.1 ST_IL_13_PATHWAY Interleukin 13 (IL-13) Pathway
0.2 8.9 PID_ARF6_PATHWAY Arf6 signaling events
0.2 3.3 SIG_IL4RECEPTOR_IN_B_LYPHOCYTES Genes related to IL4 rceptor signaling in B lymphocytes
0.2 7.5 ST_WNT_BETA_CATENIN_PATHWAY Wnt/beta-catenin Pathway
0.1 3.4 PID_ARF6_DOWNSTREAM_PATHWAY Arf6 downstream pathway
0.1 0.4 PID_AR_NONGENOMIC_PATHWAY Nongenotropic Androgen signaling
0.1 3.4 PID_EPHA_FWDPATHWAY EPHA forward signaling
0.1 6.1 PID_SHP2_PATHWAY SHP2 signaling
0.1 5.5 PID_NETRIN_PATHWAY Netrin-mediated signaling events
0.1 2.2 PID_CIRCADIAN_PATHWAY Circadian rhythm pathway
0.1 3.9 NABA_BASEMENT_MEMBRANES Genes encoding structural components of basement membranes
0.1 2.8 PID_EPHB_FWD_PATHWAY EPHB forward signaling
0.1 2.3 PID_ARF_3PATHWAY Arf1 pathway
0.1 3.7 PID_LIS1_PATHWAY Lissencephaly gene (LIS1) in neuronal migration and development
0.1 1.6 PID_S1P_META_PATHWAY Sphingosine 1-phosphate (S1P) pathway
0.1 3.1 ST_ERK1_ERK2_MAPK_PATHWAY ERK1/ERK2 MAPK Pathway
0.1 1.3 PID_ERB_GENOMIC_PATHWAY Validated nuclear estrogen receptor beta network
0.1 2.8 PID_ERBB1_INTERNALIZATION_PATHWAY Internalization of ErbB1
0.1 1.5 PID_INTEGRIN5_PATHWAY Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.1 3.0 PID_FGF_PATHWAY FGF signaling pathway
0.1 0.3 SA_PTEN_PATHWAY PTEN is a tumor suppressor that dephosphorylates the lipid messenger phosphatidylinositol triphosphate.
0.1 9.2 NABA_ECM_GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.1 1.0 PID_ERBB_NETWORK_PATHWAY ErbB receptor signaling network
0.1 1.8 PID_MYC_PATHWAY C-MYC pathway
0.1 1.5 PID_IL2_1PATHWAY IL2-mediated signaling events
0.1 1.4 PID_RAC1_REG_PATHWAY Regulation of RAC1 activity
0.1 0.5 PID_PTP1B_PATHWAY Signaling events mediated by PTP1B
0.1 0.7 PID_ALK2_PATHWAY ALK2 signaling events
0.1 0.5 PID_ERBB1_RECEPTOR_PROXIMAL_PATHWAY EGF receptor (ErbB1) signaling pathway
0.1 2.0 PID_CD8_TCR_PATHWAY TCR signaling in naïve CD8+ T cells
0.1 0.8 ST_TUMOR_NECROSIS_FACTOR_PATHWAY Tumor Necrosis Factor Pathway.
0.1 0.6 PID_IL8_CXCR1_PATHWAY IL8- and CXCR1-mediated signaling events
0.0 1.0 PID_SYNDECAN_4_PATHWAY Syndecan-4-mediated signaling events
0.0 0.8 PID_NCADHERIN_PATHWAY N-cadherin signaling events
0.0 0.5 PID_CXCR3_PATHWAY CXCR3-mediated signaling events
0.0 0.8 PID_DNA_PK_PATHWAY DNA-PK pathway in nonhomologous end joining
0.0 2.2 PID_TNF_PATHWAY TNF receptor signaling pathway
0.0 1.5 PID_ARF6_TRAFFICKING_PATHWAY Arf6 trafficking events
0.0 0.8 PID_AJDISS_2PATHWAY Posttranslational regulation of adherens junction stability and dissassembly
0.0 1.3 PID_BMP_PATHWAY BMP receptor signaling
0.0 4.1 NABA_ECM_AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.0 0.4 PID_PI3KCI_PATHWAY Class I PI3K signaling events
0.0 0.5 SA_CASPASE_CASCADE Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade.
0.0 2.1 PID_RHOA_REG_PATHWAY Regulation of RhoA activity
0.0 0.5 PID_SMAD2_3PATHWAY Regulation of cytoplasmic and nuclear SMAD2/3 signaling
0.0 0.5 PID_LYSOPHOSPHOLIPID_PATHWAY LPA receptor mediated events
0.0 0.2 PID_BETA_CATENIN_DEG_PATHWAY Degradation of beta catenin
0.0 1.0 PID_P38_ALPHA_BETA_DOWNSTREAM_PATHWAY Signaling mediated by p38-alpha and p38-beta
0.0 0.5 PID_BCR_5PATHWAY BCR signaling pathway
0.0 0.3 PID_ECADHERIN_NASCENT_AJ_PATHWAY E-cadherin signaling in the nascent adherens junction
0.0 0.5 PID_CDC42_REG_PATHWAY Regulation of CDC42 activity
0.0 1.3 PID_REG_GR_PATHWAY Glucocorticoid receptor regulatory network
0.0 0.9 PID_P75_NTR_PATHWAY p75(NTR)-mediated signaling
0.0 0.8 PID_TAP63_PATHWAY Validated transcriptional targets of TAp63 isoforms
0.0 0.3 PID_IL2_PI3K_PATHWAY IL2 signaling events mediated by PI3K
0.0 0.3 ST_MYOCYTE_AD_PATHWAY Myocyte Adrenergic Pathway is a specific case of the generalized Adrenergic Pathway.
0.0 0.9 PID_P53_REGULATION_PATHWAY p53 pathway
0.0 2.2 NABA_SECRETED_FACTORS Genes encoding secreted soluble factors
0.0 0.2 PID_P38_MKK3_6PATHWAY p38 MAPK signaling pathway
0.0 0.4 PID_MTOR_4PATHWAY mTOR signaling pathway
0.0 0.1 PID_NECTIN_PATHWAY Nectin adhesion pathway
0.0 0.2 PID_VEGFR1_2_PATHWAY Signaling events mediated by VEGFR1 and VEGFR2
0.0 0.2 PID_TGFBR_PATHWAY TGF-beta receptor signaling
0.0 0.1 PID_PI3KCI_AKT_PATHWAY Class I PI3K signaling events mediated by Akt
0.0 0.3 PID_RAC1_PATHWAY RAC1 signaling pathway

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 7.3 REACTOME_ADENYLATE_CYCLASE_ACTIVATING_PATHWAY Genes involved in Adenylate cyclase activating pathway
0.5 5.4 REACTOME_FGFR2C_LIGAND_BINDING_AND_ACTIVATION Genes involved in FGFR2c ligand binding and activation
0.3 2.4 REACTOME_TANDEM_PORE_DOMAIN_POTASSIUM_CHANNELS Genes involved in Tandem pore domain potassium channels
0.3 10.0 REACTOME_SYNTHESIS_OF_PA Genes involved in Synthesis of PA
0.3 0.9 REACTOME_SEROTONIN_RECEPTORS Genes involved in Serotonin receptors
0.3 3.0 REACTOME_ACETYLCHOLINE_NEUROTRANSMITTER_RELEASE_CYCLE Genes involved in Acetylcholine Neurotransmitter Release Cycle
0.3 2.7 REACTOME_PHOSPHORYLATION_OF_CD3_AND_TCR_ZETA_CHAINS Genes involved in Phosphorylation of CD3 and TCR zeta chains
0.3 7.9 REACTOME_UNBLOCKING_OF_NMDA_RECEPTOR_GLUTAMATE_BINDING_AND_ACTIVATION Genes involved in Unblocking of NMDA receptor, glutamate binding and activation
0.3 11.6 REACTOME_SEMA4D_IN_SEMAPHORIN_SIGNALING Genes involved in Sema4D in semaphorin signaling
0.3 3.8 REACTOME_CLASS_C_3_METABOTROPIC_GLUTAMATE_PHEROMONE_RECEPTORS Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors)
0.3 2.3 REACTOME_REGULATION_OF_INSULIN_SECRETION_BY_ACETYLCHOLINE Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.3 0.6 REACTOME_SOS_MEDIATED_SIGNALLING Genes involved in SOS-mediated signalling
0.2 4.7 REACTOME_LIGAND_GATED_ION_CHANNEL_TRANSPORT Genes involved in Ligand-gated ion channel transport
0.2 5.5 REACTOME_METAL_ION_SLC_TRANSPORTERS Genes involved in Metal ion SLC transporters
0.2 3.2 REACTOME_DEGRADATION_OF_THE_EXTRACELLULAR_MATRIX Genes involved in Degradation of the extracellular matrix
0.2 4.6 REACTOME_DCC_MEDIATED_ATTRACTIVE_SIGNALING Genes involved in DCC mediated attractive signaling
0.2 6.8 REACTOME_A_TETRASACCHARIDE_LINKER_SEQUENCE_IS_REQUIRED_FOR_GAG_SYNTHESIS Genes involved in A tetrasaccharide linker sequence is required for GAG synthesis
0.2 1.8 REACTOME_GAP_JUNCTION_DEGRADATION Genes involved in Gap junction degradation
0.2 2.5 REACTOME_ROLE_OF_DCC_IN_REGULATING_APOPTOSIS Genes involved in Role of DCC in regulating apoptosis
0.2 17.8 REACTOME_POTASSIUM_CHANNELS Genes involved in Potassium Channels
0.2 4.3 REACTOME_NEPHRIN_INTERACTIONS Genes involved in Nephrin interactions
0.2 8.0 REACTOME_DARPP_32_EVENTS Genes involved in DARPP-32 events
0.2 0.4 REACTOME_G_PROTEIN_ACTIVATION Genes involved in G-protein activation
0.2 4.8 REACTOME_RAP1_SIGNALLING Genes involved in Rap1 signalling
0.2 1.2 REACTOME_THE_NLRP3_INFLAMMASOME Genes involved in The NLRP3 inflammasome
0.1 3.2 REACTOME_HS_GAG_BIOSYNTHESIS Genes involved in HS-GAG biosynthesis
0.1 1.8 REACTOME_PLATELET_CALCIUM_HOMEOSTASIS Genes involved in Platelet calcium homeostasis
0.1 5.7 REACTOME_SPHINGOLIPID_DE_NOVO_BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis
0.1 3.1 REACTOME_KERATAN_SULFATE_BIOSYNTHESIS Genes involved in Keratan sulfate biosynthesis
0.1 2.2 REACTOME_CRMPS_IN_SEMA3A_SIGNALING Genes involved in CRMPs in Sema3A signaling
0.1 1.5 REACTOME_CTNNB1_PHOSPHORYLATION_CASCADE Genes involved in Beta-catenin phosphorylation cascade
0.1 1.6 REACTOME_REGULATION_OF_PYRUVATE_DEHYDROGENASE_PDH_COMPLEX Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.1 3.1 REACTOME_IL_RECEPTOR_SHC_SIGNALING Genes involved in Interleukin receptor SHC signaling
0.1 1.1 REACTOME_BILE_SALT_AND_ORGANIC_ANION_SLC_TRANSPORTERS Genes involved in Bile salt and organic anion SLC transporters
0.1 0.6 REACTOME_ACYL_CHAIN_REMODELLING_OF_PG Genes involved in Acyl chain remodelling of PG
0.1 4.2 REACTOME_ADHERENS_JUNCTIONS_INTERACTIONS Genes involved in Adherens junctions interactions
0.1 0.5 REACTOME_TERMINATION_OF_O_GLYCAN_BIOSYNTHESIS Genes involved in Termination of O-glycan biosynthesis
0.1 0.8 REACTOME_PLATELET_SENSITIZATION_BY_LDL Genes involved in Platelet sensitization by LDL
0.1 5.2 REACTOME_NCAM1_INTERACTIONS Genes involved in NCAM1 interactions
0.1 0.6 REACTOME_SIGNALING_BY_NODAL Genes involved in Signaling by NODAL
0.1 3.1 REACTOME_NETRIN1_SIGNALING Genes involved in Netrin-1 signaling
0.1 1.3 REACTOME_CYTOCHROME_P450_ARRANGED_BY_SUBSTRATE_TYPE Genes involved in Cytochrome P450 - arranged by substrate type
0.1 4.1 REACTOME_RECYCLING_PATHWAY_OF_L1 Genes involved in Recycling pathway of L1
0.1 1.3 REACTOME_REGULATION_OF_RHEB_GTPASE_ACTIVITY_BY_AMPK Genes involved in Regulation of Rheb GTPase activity by AMPK
0.1 2.9 REACTOME_INTERACTION_BETWEEN_L1_AND_ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.1 1.8 REACTOME_INSULIN_SYNTHESIS_AND_PROCESSING Genes involved in Insulin Synthesis and Processing
0.1 2.6 REACTOME_REGULATORY_RNA_PATHWAYS Genes involved in Regulatory RNA pathways
0.1 0.2 REACTOME_DOWNSTREAM_SIGNALING_OF_ACTIVATED_FGFR Genes involved in Downstream signaling of activated FGFR
0.1 1.9 REACTOME_CASPASE_MEDIATED_CLEAVAGE_OF_CYTOSKELETAL_PROTEINS Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.1 1.2 REACTOME_ACTIVATION_OF_IRF3_IRF7_MEDIATED_BY_TBK1_IKK_EPSILON Genes involved in Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon
0.1 0.4 REACTOME_ANDROGEN_BIOSYNTHESIS Genes involved in Androgen biosynthesis
0.1 0.8 REACTOME_TRAFFICKING_AND_PROCESSING_OF_ENDOSOMAL_TLR Genes involved in Trafficking and processing of endosomal TLR
0.1 1.0 REACTOME_CHONDROITIN_SULFATE_BIOSYNTHESIS Genes involved in Chondroitin sulfate biosynthesis
0.1 1.7 REACTOME_MITOCHONDRIAL_TRNA_AMINOACYLATION Genes involved in Mitochondrial tRNA aminoacylation
0.1 1.2 REACTOME_DOWNREGULATION_OF_ERBB2_ERBB3_SIGNALING Genes involved in Downregulation of ERBB2:ERBB3 signaling
0.1 1.5 REACTOME_TRAFFICKING_OF_AMPA_RECEPTORS Genes involved in Trafficking of AMPA receptors
0.1 2.2 REACTOME_DOWNREGULATION_OF_TGF_BETA_RECEPTOR_SIGNALING Genes involved in Downregulation of TGF-beta receptor signaling
0.1 1.9 REACTOME_SIGNALING_BY_BMP Genes involved in Signaling by BMP
0.1 1.7 REACTOME_SIGNALING_BY_FGFR1_FUSION_MUTANTS Genes involved in Signaling by FGFR1 fusion mutants
0.1 1.1 REACTOME_N_GLYCAN_ANTENNAE_ELONGATION_IN_THE_MEDIAL_TRANS_GOLGI Genes involved in N-glycan antennae elongation in the medial/trans-Golgi
0.1 0.4 REACTOME_CS_DS_DEGRADATION Genes involved in CS/DS degradation
0.1 1.1 REACTOME_CYCLIN_A_B1_ASSOCIATED_EVENTS_DURING_G2_M_TRANSITION Genes involved in Cyclin A/B1 associated events during G2/M transition
0.1 1.4 REACTOME_SYNTHESIS_OF_PIPS_AT_THE_PLASMA_MEMBRANE Genes involved in Synthesis of PIPs at the plasma membrane
0.1 0.4 REACTOME_ERKS_ARE_INACTIVATED Genes involved in ERKs are inactivated
0.1 0.7 REACTOME_PROTEOLYTIC_CLEAVAGE_OF_SNARE_COMPLEX_PROTEINS Genes involved in Proteolytic cleavage of SNARE complex proteins
0.1 1.8 REACTOME_CIRCADIAN_REPRESSION_OF_EXPRESSION_BY_REV_ERBA Genes involved in Circadian Repression of Expression by REV-ERBA
0.1 0.3 REACTOME_SYNTHESIS_OF_BILE_ACIDS_AND_BILE_SALTS_VIA_24_HYDROXYCHOLESTEROL Genes involved in Synthesis of bile acids and bile salts via 24-hydroxycholesterol
0.1 0.5 REACTOME_SIGNALING_BY_CONSTITUTIVELY_ACTIVE_EGFR Genes involved in Signaling by constitutively active EGFR
0.1 0.7 REACTOME_SYNTHESIS_OF_PE Genes involved in Synthesis of PE
0.1 0.1 REACTOME_SPRY_REGULATION_OF_FGF_SIGNALING Genes involved in Spry regulation of FGF signaling
0.1 1.4 REACTOME_CHOLESTEROL_BIOSYNTHESIS Genes involved in Cholesterol biosynthesis
0.1 1.5 REACTOME_LATENT_INFECTION_OF_HOMO_SAPIENS_WITH_MYCOBACTERIUM_TUBERCULOSIS Genes involved in Latent infection of Homo sapiens with Mycobacterium tuberculosis
0.1 0.5 REACTOME_IRON_UPTAKE_AND_TRANSPORT Genes involved in Iron uptake and transport
0.1 0.5 REACTOME_TIE2_SIGNALING Genes involved in Tie2 Signaling
0.0 0.4 REACTOME_ACYL_CHAIN_REMODELLING_OF_PC Genes involved in Acyl chain remodelling of PC
0.0 4.9 REACTOME_TRANSPORT_OF_INORGANIC_CATIONS_ANIONS_AND_AMINO_ACIDS_OLIGOPEPTIDES Genes involved in Transport of inorganic cations/anions and amino acids/oligopeptides
0.0 0.3 REACTOME_ENERGY_DEPENDENT_REGULATION_OF_MTOR_BY_LKB1_AMPK Genes involved in Energy dependent regulation of mTOR by LKB1-AMPK
0.0 0.5 REACTOME_SIGNALLING_TO_P38_VIA_RIT_AND_RIN Genes involved in Signalling to p38 via RIT and RIN
0.0 1.0 REACTOME_TRANSPORT_TO_THE_GOLGI_AND_SUBSEQUENT_MODIFICATION Genes involved in Transport to the Golgi and subsequent modification
0.0 0.3 REACTOME_ACTIVATION_OF_RAC Genes involved in Activation of Rac
0.0 0.4 REACTOME_REGULATION_OF_KIT_SIGNALING Genes involved in Regulation of KIT signaling
0.0 0.4 REACTOME_VEGF_LIGAND_RECEPTOR_INTERACTIONS Genes involved in VEGF ligand-receptor interactions
0.0 2.4 REACTOME_GOLGI_ASSOCIATED_VESICLE_BIOGENESIS Genes involved in Golgi Associated Vesicle Biogenesis
0.0 6.7 REACTOME_SIGNALING_BY_RHO_GTPASES Genes involved in Signaling by Rho GTPases
0.0 0.5 REACTOME_CD28_DEPENDENT_PI3K_AKT_SIGNALING Genes involved in CD28 dependent PI3K/Akt signaling
0.0 1.5 REACTOME_L1CAM_INTERACTIONS Genes involved in L1CAM interactions
0.0 1.1 REACTOME_BIOSYNTHESIS_OF_THE_N_GLYCAN_PRECURSOR_DOLICHOL_LIPID_LINKED_OLIGOSACCHARIDE_LLO_AND_TRANSFER_TO_A_NASCENT_PROTEIN Genes involved in Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein
0.0 0.4 REACTOME_FORMATION_OF_TUBULIN_FOLDING_INTERMEDIATES_BY_CCT_TRIC Genes involved in Formation of tubulin folding intermediates by CCT/TriC
0.0 0.4 REACTOME_CALNEXIN_CALRETICULIN_CYCLE Genes involved in Calnexin/calreticulin cycle
0.0 0.3 REACTOME_RECEPTOR_LIGAND_BINDING_INITIATES_THE_SECOND_PROTEOLYTIC_CLEAVAGE_OF_NOTCH_RECEPTOR Genes involved in Receptor-ligand binding initiates the second proteolytic cleavage of Notch receptor
0.0 0.4 REACTOME_GROWTH_HORMONE_RECEPTOR_SIGNALING Genes involved in Growth hormone receptor signaling
0.0 0.2 REACTOME_NFKB_IS_ACTIVATED_AND_SIGNALS_SURVIVAL Genes involved in NF-kB is activated and signals survival
0.0 0.1 REACTOME_ABORTIVE_ELONGATION_OF_HIV1_TRANSCRIPT_IN_THE_ABSENCE_OF_TAT Genes involved in Abortive elongation of HIV-1 transcript in the absence of Tat
0.0 1.0 REACTOME_ASSOCIATION_OF_TRIC_CCT_WITH_TARGET_PROTEINS_DURING_BIOSYNTHESIS Genes involved in Association of TriC/CCT with target proteins during biosynthesis
0.0 0.2 REACTOME_SYNTHESIS_OF_PIPS_AT_THE_LATE_ENDOSOME_MEMBRANE Genes involved in Synthesis of PIPs at the late endosome membrane
0.0 0.3 REACTOME_CA_DEPENDENT_EVENTS Genes involved in Ca-dependent events
0.0 0.7 REACTOME_ION_TRANSPORT_BY_P_TYPE_ATPASES Genes involved in Ion transport by P-type ATPases
0.0 0.8 REACTOME_GLYCOLYSIS Genes involved in Glycolysis
0.0 0.4 REACTOME_ABCA_TRANSPORTERS_IN_LIPID_HOMEOSTASIS Genes involved in ABCA transporters in lipid homeostasis
0.0 1.2 REACTOME_NUCLEAR_RECEPTOR_TRANSCRIPTION_PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.0 0.3 REACTOME_GLYCOGEN_BREAKDOWN_GLYCOGENOLYSIS Genes involved in Glycogen breakdown (glycogenolysis)
0.0 0.4 REACTOME_AMINO_ACID_SYNTHESIS_AND_INTERCONVERSION_TRANSAMINATION Genes involved in Amino acid synthesis and interconversion (transamination)
0.0 0.2 REACTOME_RNA_POL_III_CHAIN_ELONGATION Genes involved in RNA Polymerase III Chain Elongation
0.0 0.2 REACTOME_AKT_PHOSPHORYLATES_TARGETS_IN_THE_CYTOSOL Genes involved in AKT phosphorylates targets in the cytosol
0.0 0.5 REACTOME_NEP_NS2_INTERACTS_WITH_THE_CELLULAR_EXPORT_MACHINERY Genes involved in NEP/NS2 Interacts with the Cellular Export Machinery
0.0 0.3 REACTOME_PERK_REGULATED_GENE_EXPRESSION Genes involved in PERK regulated gene expression
0.0 0.4 REACTOME_ACTIVATION_OF_ATR_IN_RESPONSE_TO_REPLICATION_STRESS Genes involved in Activation of ATR in response to replication stress
0.0 0.1 REACTOME_GPVI_MEDIATED_ACTIVATION_CASCADE Genes involved in GPVI-mediated activation cascade