Motif ID: Hic2

Z-value: 1.853


Transcription factors associated with Hic2:

Gene SymbolEntrez IDGene Name
Hic2 ENSMUSG00000050240.8 Hic2

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Hic2mm10_v2_chr16_+_17233560_17233664-0.222.0e-01Click!


Activity profile for motif Hic2.

activity profile for motif Hic2


Sorted Z-values histogram for motif Hic2

Sorted Z-values for motif Hic2



Network of associatons between targets according to the STRING database.



First level regulatory network of Hic2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr12_+_61523889 14.856 ENSMUST00000119481.1
ENSMUST00000055815.7
Lrfn5

leucine rich repeat and fibronectin type III domain containing 5

chr7_-_74554474 10.348 ENSMUST00000134539.1
ENSMUST00000026897.7
ENSMUST00000098371.2
Slco3a1


solute carrier organic anion transporter family, member 3a1


chr15_-_66831625 8.541 ENSMUST00000164163.1
Sla
src-like adaptor
chr10_-_109010955 7.517 ENSMUST00000105276.1
ENSMUST00000064054.7
Syt1

synaptotagmin I

chr13_-_54055650 6.961 ENSMUST00000021932.5
Drd1a
dopamine receptor D1A
chr2_-_163918683 6.914 ENSMUST00000044734.2
Rims4
regulating synaptic membrane exocytosis 4
chr15_+_99224976 6.899 ENSMUST00000041415.3
Kcnh3
potassium voltage-gated channel, subfamily H (eag-related), member 3
chr11_+_75193783 6.875 ENSMUST00000102514.3
Rtn4rl1
reticulon 4 receptor-like 1
chr11_+_104231465 6.623 ENSMUST00000145227.1
Mapt
microtubule-associated protein tau
chr11_+_104231573 6.575 ENSMUST00000132977.1
ENSMUST00000132245.1
ENSMUST00000100347.4
Mapt


microtubule-associated protein tau


chr11_+_104231515 6.555 ENSMUST00000106993.3
Mapt
microtubule-associated protein tau
chr11_+_104231390 6.464 ENSMUST00000106992.3
Mapt
microtubule-associated protein tau
chr2_+_180499893 6.429 ENSMUST00000029084.2
Ntsr1
neurotensin receptor 1
chr1_+_74854954 6.359 ENSMUST00000160379.2
Cdk5r2
cyclin-dependent kinase 5, regulatory subunit 2 (p39)
chr7_-_74554726 6.337 ENSMUST00000107453.1
Slco3a1
solute carrier organic anion transporter family, member 3a1
chr3_+_68584154 6.280 ENSMUST00000182997.1
Schip1
schwannomin interacting protein 1
chr12_+_109549157 5.864 ENSMUST00000128458.1
ENSMUST00000150851.1
Meg3

maternally expressed 3

chr2_-_181156993 5.855 ENSMUST00000055990.7
Eef1a2
eukaryotic translation elongation factor 1 alpha 2
chr15_+_92051153 5.851 ENSMUST00000169825.1
Cntn1
contactin 1
chr5_+_81021583 5.704 ENSMUST00000121707.1
Lphn3
latrophilin 3
chr11_-_89302545 5.650 ENSMUST00000061728.3
Nog
noggin
chr11_-_81968415 5.598 ENSMUST00000066197.6
Asic2
acid-sensing (proton-gated) ion channel 2
chr1_-_56969827 5.588 ENSMUST00000176759.1
Satb2
special AT-rich sequence binding protein 2
chr13_+_58807884 5.498 ENSMUST00000079828.5
Ntrk2
neurotrophic tyrosine kinase, receptor, type 2
chr15_-_83724979 5.346 ENSMUST00000171496.1
ENSMUST00000043634.5
ENSMUST00000076060.5
ENSMUST00000016907.7
Scube1



signal peptide, CUB domain, EGF-like 1



chr1_-_56969864 5.333 ENSMUST00000177424.1
Satb2
special AT-rich sequence binding protein 2
chr3_+_123446913 5.239 ENSMUST00000029603.8
Prss12
protease, serine, 12 neurotrypsin (motopsin)
chr5_-_128953303 5.114 ENSMUST00000111346.1
Rimbp2
RIMS binding protein 2
chr19_+_8664005 5.109 ENSMUST00000035444.3
ENSMUST00000163785.1
Chrm1

cholinergic receptor, muscarinic 1, CNS

chr19_-_41206774 4.992 ENSMUST00000025986.7
ENSMUST00000169941.1
Tll2

tolloid-like 2

chr5_+_30588078 4.978 ENSMUST00000066295.2
Kcnk3
potassium channel, subfamily K, member 3
chr1_-_56978534 4.767 ENSMUST00000177282.1
Satb2
special AT-rich sequence binding protein 2
chr1_-_134234492 4.521 ENSMUST00000169927.1
Adora1
adenosine A1 receptor
chr1_-_136260873 4.451 ENSMUST00000086395.5
Gpr25
G protein-coupled receptor 25
chr11_+_97450136 4.409 ENSMUST00000107601.1
Arhgap23
Rho GTPase activating protein 23
chr12_+_87026564 4.318 ENSMUST00000110187.1
ENSMUST00000156162.1
Tmem63c

transmembrane protein 63c

chr11_+_97415527 4.267 ENSMUST00000121799.1
Arhgap23
Rho GTPase activating protein 23
chr8_+_104170513 4.207 ENSMUST00000171018.1
ENSMUST00000167633.1
ENSMUST00000093245.5
ENSMUST00000164076.1
Bean1



brain expressed, associated with Nedd4, 1



chr9_-_107710475 4.154 ENSMUST00000080560.3
Sema3f
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3F
chr1_-_154725920 4.083 ENSMUST00000004214.8
Cacna1e
calcium channel, voltage-dependent, R type, alpha 1E subunit
chr12_+_74288735 4.049 ENSMUST00000095617.1
1700086L19Rik
RIKEN cDNA 1700086L19 gene
chr1_-_134235420 3.986 ENSMUST00000038191.6
ENSMUST00000086465.4
Adora1

adenosine A1 receptor

chr13_-_98206151 3.965 ENSMUST00000109426.1
Arhgef28
Rho guanine nucleotide exchange factor (GEF) 28
chr5_+_110544326 3.962 ENSMUST00000040001.7
Galnt9
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 9
chr11_+_105975204 3.953 ENSMUST00000001964.7
Ace
angiotensin I converting enzyme (peptidyl-dipeptidase A) 1
chr12_-_67222549 3.928 ENSMUST00000037181.8
Mdga2
MAM domain containing glycosylphosphatidylinositol anchor 2
chr2_+_71981184 3.892 ENSMUST00000090826.5
ENSMUST00000102698.3
Rapgef4

Rap guanine nucleotide exchange factor (GEF) 4

chr9_-_37552904 3.889 ENSMUST00000065668.5
Nrgn
neurogranin
chr19_+_10041548 3.876 ENSMUST00000115995.2
Fads3
fatty acid desaturase 3
chr15_-_81697256 3.874 ENSMUST00000072910.5
Chadl
chondroadherin-like
chr6_+_88724828 3.857 ENSMUST00000089449.2
Mgll
monoglyceride lipase
chr7_+_29307924 3.850 ENSMUST00000108230.1
ENSMUST00000065181.5
Dpf1

D4, zinc and double PHD fingers family 1

chr6_-_115994953 3.801 ENSMUST00000015511.8
Plxnd1
plexin D1
chr2_-_113217051 3.773 ENSMUST00000080673.5
Ryr3
ryanodine receptor 3
chr2_-_27142429 3.692 ENSMUST00000151224.2
Fam163b
family with sequence similarity 163, member B
chr19_+_43440404 3.650 ENSMUST00000165311.1
Cnnm1
cyclin M1
chr14_-_39472825 3.616 ENSMUST00000168810.2
ENSMUST00000173780.1
ENSMUST00000166968.2
Nrg3


neuregulin 3


chr7_+_122671378 3.612 ENSMUST00000182563.1
Cacng3
calcium channel, voltage-dependent, gamma subunit 3
chr3_+_68494208 3.603 ENSMUST00000182719.1
Schip1
schwannomin interacting protein 1
chr13_-_92131494 3.599 ENSMUST00000099326.3
ENSMUST00000146492.1
Rasgrf2

RAS protein-specific guanine nucleotide-releasing factor 2

chr16_-_17576206 3.547 ENSMUST00000090165.4
ENSMUST00000164623.1
Slc7a4

solute carrier family 7 (cationic amino acid transporter, y+ system), member 4

chr14_+_62555737 3.536 ENSMUST00000039064.7
Fam124a
family with sequence similarity 124, member A
chr9_+_114978507 3.449 ENSMUST00000183104.1
Osbpl10
oxysterol binding protein-like 10
chr12_+_109544498 3.441 ENSMUST00000126289.1
Meg3
maternally expressed 3
chr19_+_6497772 3.438 ENSMUST00000113458.1
ENSMUST00000113459.1
Nrxn2

neurexin II

chr7_-_126704736 3.411 ENSMUST00000131415.1
Coro1a
coronin, actin binding protein 1A
chr2_+_118663235 3.397 ENSMUST00000099557.3
Pak6
p21 protein (Cdc42/Rac)-activated kinase 6
chr6_+_17306335 3.371 ENSMUST00000007799.6
ENSMUST00000115456.1
ENSMUST00000115455.2
ENSMUST00000130505.1
Cav1



caveolin 1, caveolae protein



chr4_+_13743424 3.349 ENSMUST00000006761.3
Runx1t1
runt-related transcription factor 1; translocated to, 1 (cyclin D-related)
chr11_+_104132841 3.331 ENSMUST00000093925.4
Crhr1
corticotropin releasing hormone receptor 1
chr11_-_75796048 3.329 ENSMUST00000021209.7
Doc2b
double C2, beta
chrX_-_59568068 3.295 ENSMUST00000119833.1
ENSMUST00000131319.1
Fgf13

fibroblast growth factor 13

chr13_+_42709482 3.290 ENSMUST00000066928.5
ENSMUST00000148891.1
Phactr1

phosphatase and actin regulator 1

chr2_+_156475803 3.274 ENSMUST00000029155.8
Epb4.1l1
erythrocyte protein band 4.1-like 1
chr3_+_68572245 3.269 ENSMUST00000170788.2
Schip1
schwannomin interacting protein 1
chr7_+_5056706 3.250 ENSMUST00000144802.1
Ccdc106
coiled-coil domain containing 106
chr1_+_23761749 3.189 ENSMUST00000144602.1
B3gat2
beta-1,3-glucuronyltransferase 2 (glucuronosyltransferase S)
chrX_-_48208870 3.122 ENSMUST00000088935.3
Zdhhc9
zinc finger, DHHC domain containing 9
chr1_+_134193432 3.103 ENSMUST00000038445.6
Mybph
myosin binding protein H
chr7_-_31126945 3.078 ENSMUST00000098548.4
Scn1b
sodium channel, voltage-gated, type I, beta
chr10_-_77902467 3.066 ENSMUST00000057608.4
Lrrc3
leucine rich repeat containing 3
chr14_+_57524734 3.053 ENSMUST00000089494.4
Il17d
interleukin 17D
chr4_+_152338887 3.048 ENSMUST00000005175.4
Chd5
chromodomain helicase DNA binding protein 5
chr17_+_8340399 2.987 ENSMUST00000069742.6
Prr18
proline rich region 18
chr12_+_109545390 2.952 ENSMUST00000146701.1
Meg3
maternally expressed 3
chrX_-_59134421 2.883 ENSMUST00000033473.5
Fgf13
fibroblast growth factor 13
chr6_+_54429603 2.872 ENSMUST00000132855.1
ENSMUST00000126637.1
Wipf3

WAS/WASL interacting protein family, member 3

chr18_+_51117754 2.867 ENSMUST00000116639.2
Prr16
proline rich 16
chr4_+_102570065 2.863 ENSMUST00000097950.2
Pde4b
phosphodiesterase 4B, cAMP specific
chr6_-_92481343 2.833 ENSMUST00000113445.1
Prickle2
prickle homolog 2 (Drosophila)
chr9_+_104569671 2.819 ENSMUST00000057742.8
Cpne4
copine IV
chr12_+_58211772 2.797 ENSMUST00000110671.2
ENSMUST00000044299.2
Sstr1

somatostatin receptor 1

chr7_-_84151868 2.792 ENSMUST00000117085.1
Abhd17c
abhydrolase domain containing 17C
chr9_-_77251871 2.788 ENSMUST00000183955.1
Mlip
muscular LMNA-interacting protein
chr5_-_30461902 2.782 ENSMUST00000133509.1
ENSMUST00000074171.6
ENSMUST00000114747.2
ENSMUST00000144125.1
Otof



otoferlin



chr7_+_91090697 2.775 ENSMUST00000107196.2
Dlg2
discs, large homolog 2 (Drosophila)
chr2_-_85196697 2.752 ENSMUST00000099930.2
ENSMUST00000111601.1
Lrrc55

leucine rich repeat containing 55

chr7_+_122671401 2.740 ENSMUST00000182095.1
Cacng3
calcium channel, voltage-dependent, gamma subunit 3
chr4_+_136284658 2.726 ENSMUST00000144217.1
Zfp46
zinc finger protein 46
chr10_+_13501001 2.712 ENSMUST00000060212.6
ENSMUST00000121465.2
Fuca2

fucosidase, alpha-L- 2, plasma

chr5_+_81021202 2.711 ENSMUST00000117253.1
ENSMUST00000120128.1
Lphn3

latrophilin 3

chr4_+_136284708 2.689 ENSMUST00000130223.1
Zfp46
zinc finger protein 46
chr7_+_91090728 2.672 ENSMUST00000074273.3
Dlg2
discs, large homolog 2 (Drosophila)
chr2_+_119351222 2.668 ENSMUST00000028780.3
Chac1
ChaC, cation transport regulator 1
chr5_+_36868467 2.666 ENSMUST00000031003.7
Ppp2r2c
protein phosphatase 2 (formerly 2A), regulatory subunit B (PR 52), gamma isoform
chr18_+_61105561 2.654 ENSMUST00000025523.6
Csf1r
colony stimulating factor 1 receptor
chr1_-_21961581 2.629 ENSMUST00000029667.6
ENSMUST00000173058.1
ENSMUST00000173404.1
Kcnq5


potassium voltage-gated channel, subfamily Q, member 5


chr11_+_98836775 2.592 ENSMUST00000107479.2
Rapgefl1
Rap guanine nucleotide exchange factor (GEF)-like 1
chr2_+_156475844 2.577 ENSMUST00000103135.1
Epb4.1l1
erythrocyte protein band 4.1-like 1
chr1_+_75375271 2.562 ENSMUST00000087122.5
Speg
SPEG complex locus
chr15_+_76457438 2.551 ENSMUST00000043089.7
Scx
scleraxis
chr9_+_104569754 2.510 ENSMUST00000077190.6
Cpne4
copine IV
chr4_+_152338619 2.502 ENSMUST00000030775.5
ENSMUST00000164662.1
Chd5

chromodomain helicase DNA binding protein 5

chr6_-_136875794 2.502 ENSMUST00000032342.1
Mgp
matrix Gla protein
chr5_-_118244861 2.482 ENSMUST00000117177.1
ENSMUST00000133372.1
ENSMUST00000154786.1
ENSMUST00000121369.1
Rnft2



ring finger protein, transmembrane 2



chr7_-_47132698 2.466 ENSMUST00000033142.5
Ptpn5
protein tyrosine phosphatase, non-receptor type 5
chr8_-_122551316 2.460 ENSMUST00000067252.7
Piezo1
piezo-type mechanosensitive ion channel component 1
chr11_+_83409137 2.458 ENSMUST00000021022.3
Rasl10b
RAS-like, family 10, member B
chr2_-_71546745 2.452 ENSMUST00000024159.6
Dlx2
distal-less homeobox 2
chr2_-_172043466 2.448 ENSMUST00000087950.3
Cbln4
cerebellin 4 precursor protein
chr19_+_37550397 2.445 ENSMUST00000066439.6
Exoc6
exocyst complex component 6
chr11_+_98741871 2.419 ENSMUST00000103139.4
Thra
thyroid hormone receptor alpha
chr14_+_21052574 2.389 ENSMUST00000045376.9
Adk
adenosine kinase
chr11_+_62575981 2.385 ENSMUST00000102643.1
Trpv2
transient receptor potential cation channel, subfamily V, member 2
chr6_+_88724667 2.380 ENSMUST00000163271.1
Mgll
monoglyceride lipase
chr4_-_129573637 2.342 ENSMUST00000102596.1
Lck
lymphocyte protein tyrosine kinase
chr13_+_55152640 2.341 ENSMUST00000005452.5
Fgfr4
fibroblast growth factor receptor 4
chr17_-_24527830 2.327 ENSMUST00000176353.1
ENSMUST00000176237.1
Traf7

TNF receptor-associated factor 7

chr2_+_164960809 2.287 ENSMUST00000124372.1
Slc12a5
solute carrier family 12, member 5
chr3_-_88459047 2.272 ENSMUST00000165898.1
ENSMUST00000127436.1
Sema4a

sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A

chr11_+_78032346 2.269 ENSMUST00000122342.1
ENSMUST00000092881.3
Dhrs13

dehydrogenase/reductase (SDR family) member 13

chr15_+_74516196 2.269 ENSMUST00000042035.9
Bai1
brain-specific angiogenesis inhibitor 1
chr6_-_29212240 2.252 ENSMUST00000160878.1
ENSMUST00000078155.5
Impdh1

inosine 5'-phosphate dehydrogenase 1

chr7_+_5056856 2.248 ENSMUST00000131368.1
ENSMUST00000123956.1
Ccdc106

coiled-coil domain containing 106

chr11_-_96075581 2.238 ENSMUST00000107686.1
ENSMUST00000107684.1
Atp5g1

ATP synthase, H+ transporting, mitochondrial F0 complex, subunit c1 (subunit 9)

chrX_-_133688978 2.237 ENSMUST00000149154.1
ENSMUST00000167944.1
Pcdh19

protocadherin 19

chr18_-_36515798 2.234 ENSMUST00000025363.5
Hbegf
heparin-binding EGF-like growth factor
chr7_-_126704816 2.225 ENSMUST00000032949.7
Coro1a
coronin, actin binding protein 1A
chr11_+_98741805 2.223 ENSMUST00000064187.5
Thra
thyroid hormone receptor alpha
chr3_-_116253467 2.216 ENSMUST00000090473.5
Gpr88
G-protein coupled receptor 88
chr4_-_129440800 2.199 ENSMUST00000053042.5
ENSMUST00000106046.1
Zbtb8b

zinc finger and BTB domain containing 8b

chr3_-_88458876 2.187 ENSMUST00000147200.1
ENSMUST00000169222.1
Sema4a

sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A

chr1_+_133309778 2.174 ENSMUST00000094557.4
ENSMUST00000183457.1
ENSMUST00000183738.1
ENSMUST00000185157.1
ENSMUST00000184603.1
Golt1a

Kiss1

GOLT1A
golgi transport 1 homolog A (S. cerevisiae)

KiSS-1 metastasis-suppressor

KISS1 isoform e
chr3_+_123267445 2.157 ENSMUST00000047923.7
Sec24d
Sec24 related gene family, member D (S. cerevisiae)
chr4_-_123116686 2.133 ENSMUST00000166337.1
Gm17244
predicted gene, 17244
chr8_-_71537402 2.120 ENSMUST00000051672.7
Bst2
bone marrow stromal cell antigen 2
chr11_+_73018986 2.117 ENSMUST00000092937.6
Camkk1
calcium/calmodulin-dependent protein kinase kinase 1, alpha
chr19_-_24031006 2.117 ENSMUST00000096164.4
Fam189a2
family with sequence similarity 189, member A2
chr12_+_87026286 2.115 ENSMUST00000146292.1
Tmem63c
transmembrane protein 63c
chr8_-_121907678 2.114 ENSMUST00000045557.9
Slc7a5
solute carrier family 7 (cationic amino acid transporter, y+ system), member 5
chr1_+_167001457 2.111 ENSMUST00000126198.1
Fam78b
family with sequence similarity 78, member B
chr1_+_90998722 2.108 ENSMUST00000068116.6
Lrrfip1
leucine rich repeat (in FLII) interacting protein 1
chr8_-_11312731 2.098 ENSMUST00000033898.9
Col4a1
collagen, type IV, alpha 1
chr11_+_101155884 2.066 ENSMUST00000043654.9
Tubg2
tubulin, gamma 2
chr13_-_49309217 2.052 ENSMUST00000110087.2
Fgd3
FYVE, RhoGEF and PH domain containing 3
chr8_+_11312805 2.037 ENSMUST00000033899.7
Col4a2
collagen, type IV, alpha 2
chr11_-_66525964 2.022 ENSMUST00000066679.6
Shisa6
shisa homolog 6 (Xenopus laevis)
chr4_-_42034726 2.002 ENSMUST00000084677.2
Gm21093
predicted gene, 21093
chr1_-_134332928 1.940 ENSMUST00000168515.1
Ppfia4
protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 4
chr2_+_32095518 1.934 ENSMUST00000057423.5
Ppapdc3
phosphatidic acid phosphatase type 2 domain containing 3
chr7_+_28982832 1.927 ENSMUST00000085835.6
Map4k1
mitogen-activated protein kinase kinase kinase kinase 1
chr19_+_41981709 1.923 ENSMUST00000026170.1
Ubtd1
ubiquitin domain containing 1
chr19_+_6401675 1.912 ENSMUST00000113471.1
ENSMUST00000113469.2
Rasgrp2

RAS, guanyl releasing protein 2

chr7_-_4789541 1.911 ENSMUST00000168578.1
Tmem238
transmembrane protein 238
chr15_-_64382736 1.909 ENSMUST00000176384.1
ENSMUST00000175799.1
Asap1

ArfGAP with SH3 domain, ankyrin repeat and PH domain1

chr3_-_153725062 1.890 ENSMUST00000064460.5
St6galnac3
ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 3
chr14_+_70555900 1.883 ENSMUST00000163060.1
Hr
hairless
chr19_+_23758819 1.878 ENSMUST00000025830.7
Apba1
amyloid beta (A4) precursor protein binding, family A, member 1
chr12_+_85599388 1.866 ENSMUST00000050687.6
Jdp2
Jun dimerization protein 2
chr6_-_136941494 1.863 ENSMUST00000111892.1
Arhgdib
Rho, GDP dissociation inhibitor (GDI) beta
chr15_+_87625214 1.862 ENSMUST00000068088.6
Fam19a5
family with sequence similarity 19, member A5
chr8_+_23139030 1.859 ENSMUST00000121075.1
Ank1
ankyrin 1, erythroid
chr10_-_43174521 1.852 ENSMUST00000040275.7
Sobp
sine oculis-binding protein homolog (Drosophila)
chr2_+_32629467 1.847 ENSMUST00000068271.4
Ak1
adenylate kinase 1
chr14_+_19751257 1.846 ENSMUST00000022340.3
Nid2
nidogen 2
chr14_-_66213552 1.840 ENSMUST00000178730.1
Ptk2b
PTK2 protein tyrosine kinase 2 beta
chr11_+_78324200 1.831 ENSMUST00000102478.3
Aldoc
aldolase C, fructose-bisphosphate
chr11_+_83409655 1.830 ENSMUST00000175848.1
ENSMUST00000108140.3
Rasl10b

RAS-like, family 10, member B

chr11_+_19924354 1.828 ENSMUST00000093299.6
Spred2
sprouty-related, EVH1 domain containing 2
chr17_-_24209377 1.817 ENSMUST00000024931.4
Ntn3
netrin 3
chr4_+_117835387 1.816 ENSMUST00000169885.1
Slc6a9
solute carrier family 6 (neurotransmitter transporter, glycine), member 9
chr4_+_43384332 1.813 ENSMUST00000136360.1
Rusc2
RUN and SH3 domain containing 2
chr6_-_99520949 1.803 ENSMUST00000176565.1
Foxp1
forkhead box P1
chr10_-_11082287 1.790 ENSMUST00000105561.2
ENSMUST00000044306.6
Grm1

glutamate receptor, metabotropic 1

chr15_-_79285502 1.786 ENSMUST00000165408.1
Baiap2l2
BAI1-associated protein 2-like 2
chr5_+_140607334 1.768 ENSMUST00000031555.1
Lfng
LFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase
chr19_-_6118491 1.762 ENSMUST00000113533.1
Sac3d1
SAC3 domain containing 1
chr14_-_21848924 1.759 ENSMUST00000124549.1
Comtd1
catechol-O-methyltransferase domain containing 1
chr10_-_11080956 1.758 ENSMUST00000105560.1
Grm1
glutamate receptor, metabotropic 1
chr2_-_152398046 1.757 ENSMUST00000063332.8
ENSMUST00000182625.1
Sox12

SRY-box containing gene 12

chr2_-_57113053 1.753 ENSMUST00000112627.1
Nr4a2
nuclear receptor subfamily 4, group A, member 2
chr1_-_190979280 1.742 ENSMUST00000166139.1
Vash2
vasohibin 2
chr4_-_124850473 1.736 ENSMUST00000137769.2
1110065P20Rik
RIKEN cDNA 1110065P20 gene
chr9_-_107985863 1.733 ENSMUST00000048568.4
Fam212a
family with sequence similarity 212, member A
chr7_+_113765998 1.725 ENSMUST00000046687.9
Spon1
spondin 1, (f-spondin) extracellular matrix protein
chr12_-_25096080 1.723 ENSMUST00000020974.6
Id2
inhibitor of DNA binding 2
chr2_+_25242929 1.721 ENSMUST00000114355.1
ENSMUST00000060818.1
Rnf208

ring finger protein 208

chr7_+_49246131 1.694 ENSMUST00000064395.6
Nav2
neuron navigator 2
chr2_+_136891501 1.686 ENSMUST00000141463.1
Slx4ip
SLX4 interacting protein
chr1_+_171411305 1.686 ENSMUST00000161241.1
ENSMUST00000159207.1
Usf1

upstream transcription factor 1


Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
2.9 26.2 GO:1900034 regulation of cellular response to heat(GO:1900034)
2.8 8.5 GO:0032241 positive regulation of nucleobase-containing compound transport(GO:0032241) regulation of nucleoside transport(GO:0032242) negative regulation of circadian sleep/wake cycle, non-REM sleep(GO:0042323) negative regulation of mucus secretion(GO:0070256)
1.8 5.3 GO:0050915 sensory perception of sour taste(GO:0050915)
1.6 6.4 GO:0090238 positive regulation of arachidonic acid secretion(GO:0090238)
1.6 6.4 GO:0021586 pons maturation(GO:0021586)
1.5 4.6 GO:0017055 negative regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0017055)
1.4 9.5 GO:2000124 regulation of endocannabinoid signaling pathway(GO:2000124)
1.3 4.0 GO:2000170 positive regulation of peptidyl-cysteine S-nitrosylation(GO:2000170)
1.3 3.9 GO:1903054 negative regulation of extracellular matrix organization(GO:1903054)
1.3 16.6 GO:0015732 prostaglandin transport(GO:0015732)
1.3 5.1 GO:0051866 general adaptation syndrome(GO:0051866)
1.2 7.4 GO:0000160 phosphorelay signal transduction system(GO:0000160)
1.2 3.6 GO:0060596 mammary placode formation(GO:0060596)
1.2 7.1 GO:0032796 uropod organization(GO:0032796)
1.2 4.7 GO:2000313 fibroblast growth factor receptor signaling pathway involved in neural plate anterior/posterior pattern formation(GO:0060825) regulation of fibroblast growth factor receptor signaling pathway involved in neural plate anterior/posterior pattern formation(GO:2000313)
1.0 1.0 GO:0045608 inhibition of neuroepithelial cell differentiation(GO:0002085) negative regulation of auditory receptor cell differentiation(GO:0045608)
1.0 5.1 GO:0007197 adenylate cyclase-inhibiting G-protein coupled acetylcholine receptor signaling pathway(GO:0007197) phospholipase C-activating G-protein coupled acetylcholine receptor signaling pathway(GO:0007207)
1.0 5.0 GO:0048631 regulation of skeletal muscle tissue growth(GO:0048631)
1.0 3.9 GO:1904457 positive regulation of neuronal action potential(GO:1904457)
1.0 4.8 GO:1903609 negative regulation of peptidyl-tyrosine autophosphorylation(GO:1900085) negative regulation of inward rectifier potassium channel activity(GO:1903609)
0.9 2.8 GO:0001830 trophectodermal cell fate commitment(GO:0001830)
0.9 3.5 GO:0099566 regulation of postsynaptic cytosolic calcium ion concentration(GO:0099566)
0.9 6.2 GO:0098909 establishment or maintenance of neuroblast polarity(GO:0045196) establishment of neuroblast polarity(GO:0045200) regulation of cardiac muscle cell action potential involved in regulation of contraction(GO:0098909)
0.9 7.0 GO:0005513 detection of calcium ion(GO:0005513)
0.9 2.6 GO:0061056 sclerotome development(GO:0061056)
0.8 0.8 GO:0071926 endocannabinoid signaling pathway(GO:0071926)
0.8 2.5 GO:0033634 positive regulation of cell-cell adhesion mediated by integrin(GO:0033634)
0.8 13.1 GO:0021902 commitment of neuronal cell to specific neuron type in forebrain(GO:0021902)
0.8 2.5 GO:0061075 cerebral cortex GABAergic interneuron fate commitment(GO:0021893) positive regulation of neural retina development(GO:0061075) positive regulation of retina development in camera-type eye(GO:1902868) positive regulation of amacrine cell differentiation(GO:1902871)
0.8 2.4 GO:0009153 purine deoxyribonucleotide biosynthetic process(GO:0009153)
0.8 2.4 GO:0048865 stem cell fate commitment(GO:0048865) stem cell fate specification(GO:0048866)
0.8 5.6 GO:0035093 spermatogenesis, exchange of chromosomal proteins(GO:0035093)
0.8 2.3 GO:0061144 alveolar secondary septum development(GO:0061144)
0.8 3.1 GO:0021966 corticospinal neuron axon guidance(GO:0021966)
0.7 2.2 GO:0051542 elastin biosynthetic process(GO:0051542)
0.7 13.9 GO:0001553 luteinization(GO:0001553)
0.7 2.1 GO:1902219 negative regulation of intrinsic apoptotic signaling pathway in response to osmotic stress(GO:1902219)
0.7 4.2 GO:0097491 trunk segmentation(GO:0035290) trunk neural crest cell migration(GO:0036484) ventral trunk neural crest cell migration(GO:0036486) sympathetic neuron projection extension(GO:0097490) sympathetic neuron projection guidance(GO:0097491)
0.7 5.4 GO:0099550 trans-synaptic signalling, modulating synaptic transmission(GO:0099550)
0.7 3.4 GO:0019086 regulation of transcription from RNA polymerase II promoter by glucose(GO:0000430) positive regulation of transcription from RNA polymerase II promoter by glucose(GO:0000432) late viral transcription(GO:0019086)
0.7 0.7 GO:0008063 Toll signaling pathway(GO:0008063)
0.7 2.6 GO:0006751 glutathione catabolic process(GO:0006751)
0.7 2.6 GO:0038145 macrophage colony-stimulating factor signaling pathway(GO:0038145)
0.6 1.3 GO:0001757 somite specification(GO:0001757)
0.6 1.9 GO:2000344 positive regulation of acrosome reaction(GO:2000344)
0.6 3.1 GO:0030644 cellular chloride ion homeostasis(GO:0030644)
0.6 1.8 GO:0010752 signal complex assembly(GO:0007172) regulation of cGMP-mediated signaling(GO:0010752)
0.6 1.8 GO:0018199 peptidyl-glutamine modification(GO:0018199)
0.6 1.8 GO:0061537 glycine secretion(GO:0061536) glycine secretion, neurotransmission(GO:0061537)
0.6 1.2 GO:0021773 striatal medium spiny neuron differentiation(GO:0021773)
0.6 0.6 GO:0002191 cap-dependent translational initiation(GO:0002191)
0.5 2.2 GO:0032275 luteinizing hormone secretion(GO:0032275) positive regulation of gonadotropin secretion(GO:0032278)
0.5 1.6 GO:0030321 transepithelial chloride transport(GO:0030321)
0.5 2.1 GO:1901252 regulation of intracellular transport of viral material(GO:1901252)
0.5 2.1 GO:0051092 positive regulation of NF-kappaB transcription factor activity(GO:0051092)
0.5 2.0 GO:0021564 glossopharyngeal nerve development(GO:0021563) vagus nerve development(GO:0021564)
0.5 1.0 GO:0033159 negative regulation of protein import into nucleus, translocation(GO:0033159)
0.5 3.0 GO:0070278 extracellular matrix constituent secretion(GO:0070278)
0.5 2.0 GO:0003430 growth plate cartilage chondrocyte growth(GO:0003430)
0.5 1.5 GO:0046381 CMP-N-acetylneuraminate metabolic process(GO:0046381)
0.5 5.0 GO:0030322 stabilization of membrane potential(GO:0030322)
0.5 1.5 GO:0097500 receptor localization to nonmotile primary cilium(GO:0097500)
0.5 2.5 GO:2001025 positive regulation of response to drug(GO:2001025)
0.5 1.0 GO:0035855 megakaryocyte development(GO:0035855)
0.5 2.4 GO:0071688 striated muscle myosin thick filament assembly(GO:0071688)
0.5 1.5 GO:0098528 skeletal muscle fiber differentiation(GO:0098528)
0.5 12.2 GO:0008340 determination of adult lifespan(GO:0008340)
0.5 2.3 GO:0006177 GMP biosynthetic process(GO:0006177)
0.5 0.5 GO:0003219 cardiac right ventricle formation(GO:0003219)
0.4 0.9 GO:0031620 fever generation(GO:0001660) regulation of fever generation(GO:0031620)
0.4 4.9 GO:0000185 activation of MAPKKK activity(GO:0000185)
0.4 1.8 GO:0007386 compartment pattern specification(GO:0007386)
0.4 1.8 GO:0061743 motor learning(GO:0061743)
0.4 1.3 GO:0015886 heme transport(GO:0015886)
0.4 1.3 GO:0045793 positive regulation of cell size(GO:0045793)
0.4 6.9 GO:0048681 negative regulation of axon regeneration(GO:0048681)
0.4 2.1 GO:0002457 T cell antigen processing and presentation(GO:0002457)
0.4 1.2 GO:0006597 spermine biosynthetic process(GO:0006597)
0.4 1.7 GO:0060754 positive regulation of mast cell chemotaxis(GO:0060754)
0.4 1.6 GO:0032713 negative regulation of interleukin-4 production(GO:0032713)
0.4 2.0 GO:0038063 collagen-activated tyrosine kinase receptor signaling pathway(GO:0038063)
0.4 0.4 GO:0090403 oxidative stress-induced premature senescence(GO:0090403)
0.4 1.6 GO:2000182 regulation of progesterone biosynthetic process(GO:2000182)
0.4 2.4 GO:1900121 negative regulation of receptor binding(GO:1900121)
0.4 1.6 GO:0070305 response to cGMP(GO:0070305) cellular response to cGMP(GO:0071321)
0.4 1.6 GO:1903265 positive regulation of tumor necrosis factor-mediated signaling pathway(GO:1903265)
0.4 2.3 GO:0046645 positive regulation of gamma-delta T cell differentiation(GO:0045588) positive regulation of gamma-delta T cell activation(GO:0046645)
0.4 5.4 GO:0045161 neuronal ion channel clustering(GO:0045161)
0.4 1.9 GO:1903527 positive regulation of membrane tubulation(GO:1903527)
0.4 1.1 GO:0044339 canonical Wnt signaling pathway involved in osteoblast differentiation(GO:0044339)
0.4 2.6 GO:0016480 negative regulation of transcription from RNA polymerase III promoter(GO:0016480)
0.4 1.5 GO:0070166 enamel mineralization(GO:0070166)
0.4 0.7 GO:0032274 gonadotropin secretion(GO:0032274)
0.4 1.4 GO:0072061 inner medullary collecting duct development(GO:0072061)
0.3 2.1 GO:0061304 retinal blood vessel morphogenesis(GO:0061304)
0.3 1.7 GO:0045578 negative regulation of B cell differentiation(GO:0045578) epithelial cell differentiation involved in mammary gland alveolus development(GO:0061030)
0.3 2.1 GO:1901164 negative regulation of trophoblast cell migration(GO:1901164)
0.3 2.7 GO:0035635 entry of bacterium into host cell(GO:0035635) regulation of entry of bacterium into host cell(GO:2000535)
0.3 1.3 GO:0060666 dichotomous subdivision of terminal units involved in salivary gland branching(GO:0060666)
0.3 1.0 GO:0018214 peptidyl-glutamic acid carboxylation(GO:0017187) protein carboxylation(GO:0018214)
0.3 1.0 GO:0072720 response to sorbitol(GO:0072708) response to dithiothreitol(GO:0072720)
0.3 1.0 GO:0019043 establishment of viral latency(GO:0019043)
0.3 1.6 GO:0006538 glutamate catabolic process(GO:0006538)
0.3 1.3 GO:0033563 dorsal/ventral axon guidance(GO:0033563)
0.3 1.3 GO:0010626 negative regulation of Schwann cell proliferation(GO:0010626)
0.3 0.6 GO:1903377 negative regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway(GO:1903377)
0.3 0.9 GO:0042126 nitrate metabolic process(GO:0042126)
0.3 0.3 GO:0097374 sensory neuron axon guidance(GO:0097374)
0.3 1.2 GO:0033762 response to glucagon(GO:0033762)
0.3 1.8 GO:0009136 ADP biosynthetic process(GO:0006172) purine nucleoside diphosphate biosynthetic process(GO:0009136) purine ribonucleoside diphosphate biosynthetic process(GO:0009180) inosine biosynthetic process(GO:0046103)
0.3 0.6 GO:0009826 unidimensional cell growth(GO:0009826)
0.3 8.5 GO:2000311 regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity(GO:2000311)
0.3 0.6 GO:0014012 peripheral nervous system axon regeneration(GO:0014012)
0.3 0.6 GO:1902262 apoptotic process involved in patterning of blood vessels(GO:1902262)
0.3 1.8 GO:2000323 negative regulation of glucocorticoid receptor signaling pathway(GO:2000323)
0.3 3.8 GO:0051481 negative regulation of cytosolic calcium ion concentration(GO:0051481)
0.3 1.1 GO:2000277 positive regulation of oxidative phosphorylation uncoupler activity(GO:2000277)
0.3 3.4 GO:0071625 vocalization behavior(GO:0071625)
0.3 3.1 GO:0018230 peptidyl-L-cysteine S-palmitoylation(GO:0018230) peptidyl-S-diacylglycerol-L-cysteine biosynthetic process from peptidyl-cysteine(GO:0018231)
0.3 4.0 GO:0060052 neurofilament cytoskeleton organization(GO:0060052)
0.3 0.8 GO:0033615 mitochondrial proton-transporting ATP synthase complex assembly(GO:0033615)
0.3 1.7 GO:0061343 cell adhesion involved in heart morphogenesis(GO:0061343)
0.3 8.9 GO:0048791 calcium ion-regulated exocytosis of neurotransmitter(GO:0048791)
0.3 0.6 GO:0009247 glycolipid biosynthetic process(GO:0009247)
0.3 0.6 GO:0001938 positive regulation of endothelial cell proliferation(GO:0001938)
0.3 0.6 GO:0002408 myeloid dendritic cell chemotaxis(GO:0002408)
0.3 0.8 GO:0048014 Tie signaling pathway(GO:0048014)
0.3 0.8 GO:0046952 ketone body catabolic process(GO:0046952)
0.3 1.3 GO:0043084 penile erection(GO:0043084)
0.3 0.8 GO:0033566 gamma-tubulin complex localization(GO:0033566)
0.3 6.9 GO:0030204 chondroitin sulfate metabolic process(GO:0030204)
0.3 0.8 GO:0035523 protein K29-linked deubiquitination(GO:0035523) protein K6-linked deubiquitination(GO:0044313)
0.3 2.1 GO:0006003 fructose 2,6-bisphosphate metabolic process(GO:0006003)
0.3 3.6 GO:2000310 regulation of N-methyl-D-aspartate selective glutamate receptor activity(GO:2000310)
0.3 0.8 GO:0043988 histone H3-S28 phosphorylation(GO:0043988)
0.3 0.8 GO:0019405 alditol catabolic process(GO:0019405) glyceraldehyde-3-phosphate biosynthetic process(GO:0046166)
0.3 1.3 GO:0033631 cell-cell adhesion mediated by integrin(GO:0033631)
0.2 1.0 GO:0072014 proximal tubule development(GO:0072014)
0.2 1.0 GO:0006244 pyrimidine nucleotide catabolic process(GO:0006244) pyrimidine deoxyribonucleotide catabolic process(GO:0009223)
0.2 1.2 GO:0015671 oxygen transport(GO:0015671)
0.2 2.6 GO:1990173 protein localization to nuclear body(GO:1903405) protein localization to Cajal body(GO:1904867) regulation of protein localization to Cajal body(GO:1904869) positive regulation of protein localization to Cajal body(GO:1904871) protein localization to nucleoplasm(GO:1990173)
0.2 1.2 GO:0097501 stress response to metal ion(GO:0097501)
0.2 0.7 GO:0051030 snRNA transport(GO:0051030)
0.2 1.2 GO:0000454 snoRNA guided rRNA pseudouridine synthesis(GO:0000454)
0.2 0.7 GO:1903244 positive regulation of cardiac muscle adaptation(GO:0010615) connective tissue replacement(GO:0097709) positive regulation of cardiac muscle hypertrophy in response to stress(GO:1903244) regulation of connective tissue replacement(GO:1905203)
0.2 0.7 GO:2000304 positive regulation of sphingolipid biosynthetic process(GO:0090154) positive regulation of ceramide biosynthetic process(GO:2000304)
0.2 2.8 GO:1903818 positive regulation of voltage-gated potassium channel activity(GO:1903818)
0.2 0.9 GO:0006420 arginyl-tRNA aminoacylation(GO:0006420)
0.2 1.4 GO:0006452 translational frameshifting(GO:0006452) positive regulation of translational termination(GO:0045905)
0.2 1.1 GO:1901731 positive regulation of platelet aggregation(GO:1901731)
0.2 4.5 GO:0048266 behavioral response to pain(GO:0048266)
0.2 0.7 GO:1990523 bone regeneration(GO:1990523)
0.2 0.7 GO:0006449 regulation of translational termination(GO:0006449)
0.2 2.9 GO:1901898 negative regulation of relaxation of muscle(GO:1901078) negative regulation of relaxation of cardiac muscle(GO:1901898)
0.2 4.8 GO:0045063 T-helper 1 cell differentiation(GO:0045063)
0.2 0.4 GO:2000812 regulation of barbed-end actin filament capping(GO:2000812)
0.2 0.6 GO:0071918 urea transmembrane transport(GO:0071918)
0.2 4.0 GO:1900273 positive regulation of long-term synaptic potentiation(GO:1900273)
0.2 0.6 GO:0042196 dichloromethane metabolic process(GO:0018900) chlorinated hydrocarbon metabolic process(GO:0042196) halogenated hydrocarbon metabolic process(GO:0042197)
0.2 2.5 GO:0070389 chaperone cofactor-dependent protein refolding(GO:0070389)
0.2 0.6 GO:1902396 protein localization to bicellular tight junction(GO:1902396)
0.2 1.0 GO:0042535 positive regulation of tumor necrosis factor biosynthetic process(GO:0042535)
0.2 0.4 GO:0048298 positive regulation of isotype switching to IgA isotypes(GO:0048298)
0.2 2.1 GO:2001269 positive regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway(GO:2001269)
0.2 0.8 GO:0050913 sensory perception of bitter taste(GO:0050913)
0.2 1.6 GO:2000786 positive regulation of autophagosome assembly(GO:2000786)
0.2 1.0 GO:0034372 very-low-density lipoprotein particle remodeling(GO:0034372)
0.2 1.8 GO:0046543 development of secondary female sexual characteristics(GO:0046543)
0.2 1.0 GO:0019236 response to pheromone(GO:0019236)
0.2 0.6 GO:0051295 establishment of meiotic spindle localization(GO:0051295) formin-nucleated actin cable assembly(GO:0070649)
0.2 0.6 GO:0009446 putrescine biosynthetic process(GO:0009446)
0.2 1.0 GO:0048245 eosinophil chemotaxis(GO:0048245) T cell extravasation(GO:0072683)
0.2 0.8 GO:0019372 lipoxygenase pathway(GO:0019372)
0.2 0.6 GO:1902951 negative regulation of dendritic spine maintenance(GO:1902951)
0.2 1.3 GO:0032261 purine nucleotide salvage(GO:0032261) IMP salvage(GO:0032264)
0.2 3.4 GO:0018345 protein palmitoylation(GO:0018345)
0.2 0.8 GO:1903898 positive regulation of translation in response to endoplasmic reticulum stress(GO:0036493) negative regulation of PERK-mediated unfolded protein response(GO:1903898)
0.2 1.1 GO:0090527 actin filament reorganization(GO:0090527)
0.2 0.2 GO:2000974 negative regulation of mechanoreceptor differentiation(GO:0045632) negative regulation of pro-B cell differentiation(GO:2000974) negative regulation of inner ear receptor cell differentiation(GO:2000981)
0.2 2.2 GO:0060480 lung goblet cell differentiation(GO:0060480)
0.2 1.9 GO:0019243 methylglyoxal catabolic process to D-lactate via S-lactoyl-glutathione(GO:0019243) methylglyoxal catabolic process(GO:0051596) methylglyoxal catabolic process to lactate(GO:0061727)
0.2 2.0 GO:0048172 regulation of short-term neuronal synaptic plasticity(GO:0048172)
0.2 1.8 GO:0030388 fructose 1,6-bisphosphate metabolic process(GO:0030388)
0.2 0.9 GO:0060346 bone trabecula formation(GO:0060346)
0.2 1.1 GO:0035435 phosphate ion transmembrane transport(GO:0035435)
0.2 1.1 GO:0090343 positive regulation of cell aging(GO:0090343)
0.2 2.1 GO:1900119 positive regulation of execution phase of apoptosis(GO:1900119)
0.2 2.8 GO:0070262 peptidyl-serine dephosphorylation(GO:0070262)
0.2 1.4 GO:2000601 positive regulation of Arp2/3 complex-mediated actin nucleation(GO:2000601)
0.2 0.9 GO:1990034 calcium ion export from cell(GO:1990034)
0.2 0.5 GO:0006434 seryl-tRNA aminoacylation(GO:0006434)
0.2 1.2 GO:1900042 positive regulation of interleukin-2 secretion(GO:1900042)
0.2 5.7 GO:0003333 amino acid transmembrane transport(GO:0003333)
0.2 1.5 GO:0001574 ganglioside biosynthetic process(GO:0001574) lipid glycosylation(GO:0030259)
0.2 1.4 GO:0031424 keratinization(GO:0031424)
0.2 1.5 GO:0038203 TORC2 signaling(GO:0038203)
0.2 4.4 GO:0015991 ATP hydrolysis coupled proton transport(GO:0015991)
0.2 1.8 GO:0043517 positive regulation of DNA damage response, signal transduction by p53 class mediator(GO:0043517)
0.2 0.3 GO:0006550 isoleucine catabolic process(GO:0006550)
0.2 0.7 GO:0002339 B cell selection(GO:0002339)
0.2 0.8 GO:0045919 positive regulation of cytolysis(GO:0045919)
0.2 0.7 GO:0002924 negative regulation of humoral immune response mediated by circulating immunoglobulin(GO:0002924)
0.2 1.1 GO:0009449 gamma-aminobutyric acid biosynthetic process(GO:0009449)
0.2 0.3 GO:0070970 interleukin-2 secretion(GO:0070970)
0.2 1.9 GO:0070986 left/right axis specification(GO:0070986)
0.2 2.0 GO:0044065 regulation of respiratory system process(GO:0044065)
0.2 0.9 GO:1901029 negative regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway(GO:1901029)
0.2 1.6 GO:0072643 interferon-gamma secretion(GO:0072643)
0.2 1.2 GO:2000491 positive regulation of hepatic stellate cell activation(GO:2000491)
0.2 0.8 GO:1903772 regulation of viral budding via host ESCRT complex(GO:1903772)
0.2 1.1 GO:0016185 synaptic vesicle budding from presynaptic endocytic zone membrane(GO:0016185)
0.1 0.4 GO:0071544 diphosphoinositol polyphosphate catabolic process(GO:0071544)
0.1 5.3 GO:0045880 positive regulation of smoothened signaling pathway(GO:0045880)
0.1 2.0 GO:0090110 cargo loading into COPII-coated vesicle(GO:0090110)
0.1 1.3 GO:0070995 NADPH oxidation(GO:0070995)
0.1 6.8 GO:0006414 translational elongation(GO:0006414)
0.1 1.6 GO:0044539 long-chain fatty acid import(GO:0044539)
0.1 0.5 GO:0021812 neuronal-glial interaction involved in cerebral cortex radial glia guided migration(GO:0021812)
0.1 0.5 GO:0035606 peptidyl-cysteine S-trans-nitrosylation(GO:0035606)
0.1 0.3 GO:0048597 post-embryonic camera-type eye morphogenesis(GO:0048597)
0.1 0.6 GO:0015871 choline transport(GO:0015871) negative regulation of RIG-I signaling pathway(GO:0039536)
0.1 2.3 GO:0019835 cytolysis(GO:0019835)
0.1 0.5 GO:0030576 Cajal body organization(GO:0030576)
0.1 0.5 GO:0006049 UDP-N-acetylglucosamine catabolic process(GO:0006049)
0.1 0.5 GO:0019919 peptidyl-arginine methylation, to asymmetrical-dimethyl arginine(GO:0019919)
0.1 1.4 GO:2000653 regulation of genetic imprinting(GO:2000653)
0.1 2.5 GO:0006677 glycosylceramide metabolic process(GO:0006677)
0.1 1.9 GO:0014051 gamma-aminobutyric acid secretion(GO:0014051)
0.1 0.6 GO:2000255 negative regulation of male germ cell proliferation(GO:2000255)
0.1 1.1 GO:0006020 inositol metabolic process(GO:0006020)
0.1 1.2 GO:0071318 cellular response to ATP(GO:0071318)
0.1 2.2 GO:0071392 cellular response to estradiol stimulus(GO:0071392)
0.1 0.6 GO:1902775 mitochondrial large ribosomal subunit assembly(GO:1902775)
0.1 0.6 GO:0006672 ceramide metabolic process(GO:0006672)
0.1 0.9 GO:2000232 regulation of rRNA processing(GO:2000232)
0.1 0.4 GO:0070966 nuclear-transcribed mRNA catabolic process, no-go decay(GO:0070966)
0.1 3.3 GO:0060716 labyrinthine layer blood vessel development(GO:0060716)
0.1 0.9 GO:0043951 negative regulation of cAMP-mediated signaling(GO:0043951)
0.1 1.0 GO:1901621 negative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning(GO:1901621)
0.1 1.9 GO:0016082 synaptic vesicle priming(GO:0016082)
0.1 1.4 GO:0051968 positive regulation of synaptic transmission, glutamatergic(GO:0051968)
0.1 0.9 GO:0018401 peptidyl-proline hydroxylation to 4-hydroxy-L-proline(GO:0018401)
0.1 0.7 GO:0098707 ferrous iron import into cell(GO:0097460) ferrous iron import across plasma membrane(GO:0098707)
0.1 1.8 GO:2000251 positive regulation of actin cytoskeleton reorganization(GO:2000251)
0.1 0.7 GO:1903026 negative regulation of RNA polymerase II regulatory region sequence-specific DNA binding(GO:1903026)
0.1 0.3 GO:0036296 cellular response to increased oxygen levels(GO:0036295) response to increased oxygen levels(GO:0036296)
0.1 1.4 GO:2000463 positive regulation of excitatory postsynaptic potential(GO:2000463)
0.1 1.7 GO:2000353 positive regulation of endothelial cell apoptotic process(GO:2000353)
0.1 0.3 GO:0043379 rRNA export from nucleus(GO:0006407) memory T cell differentiation(GO:0043379) response to oxygen-glucose deprivation(GO:0090649) cellular response to oxygen-glucose deprivation(GO:0090650)
0.1 5.0 GO:0038083 peptidyl-tyrosine autophosphorylation(GO:0038083)
0.1 2.9 GO:0007020 microtubule nucleation(GO:0007020)
0.1 2.4 GO:0045662 negative regulation of myoblast differentiation(GO:0045662)
0.1 2.8 GO:0010614 negative regulation of cardiac muscle hypertrophy(GO:0010614)
0.1 2.1 GO:0001990 regulation of systemic arterial blood pressure by hormone(GO:0001990)
0.1 0.5 GO:0010735 positive regulation of transcription via serum response element binding(GO:0010735)
0.1 0.3 GO:0098974 postsynaptic actin cytoskeleton organization(GO:0098974)
0.1 1.3 GO:0048280 vesicle fusion with Golgi apparatus(GO:0048280)
0.1 0.9 GO:2001197 positive regulation of extracellular matrix assembly(GO:1901203) regulation of basement membrane assembly involved in embryonic body morphogenesis(GO:1904259) positive regulation of basement membrane assembly involved in embryonic body morphogenesis(GO:1904261) basement membrane assembly involved in embryonic body morphogenesis(GO:2001197)
0.1 1.1 GO:0002347 response to tumor cell(GO:0002347)
0.1 0.6 GO:0007016 cytoskeletal anchoring at plasma membrane(GO:0007016)
0.1 1.3 GO:0070842 aggresome assembly(GO:0070842)
0.1 0.4 GO:0006121 mitochondrial electron transport, succinate to ubiquinone(GO:0006121)
0.1 0.4 GO:1990022 RNA polymerase II complex import to nucleus(GO:0044376) RNA polymerase III complex localization to nucleus(GO:1990022)
0.1 0.5 GO:0072429 response to intra-S DNA damage checkpoint signaling(GO:0072429)
0.1 1.5 GO:0099612 protein localization to axon(GO:0099612)
0.1 1.2 GO:0000478 endonucleolytic cleavage involved in rRNA processing(GO:0000478)
0.1 0.5 GO:0007258 JUN phosphorylation(GO:0007258)
0.1 3.3 GO:0048821 erythrocyte development(GO:0048821)
0.1 1.1 GO:0006465 signal peptide processing(GO:0006465)
0.1 0.5 GO:1902416 positive regulation of mRNA binding(GO:1902416)
0.1 1.4 GO:0034389 lipid particle organization(GO:0034389)
0.1 5.6 GO:0010923 negative regulation of phosphatase activity(GO:0010923)
0.1 0.9 GO:0045956 positive regulation of calcium ion-dependent exocytosis(GO:0045956)
0.1 3.8 GO:0045599 negative regulation of fat cell differentiation(GO:0045599)
0.1 0.3 GO:0019732 antifungal humoral response(GO:0019732) antifungal innate immune response(GO:0061760)
0.1 0.6 GO:0060394 negative regulation of pathway-restricted SMAD protein phosphorylation(GO:0060394)
0.1 0.2 GO:0010641 positive regulation of platelet-derived growth factor receptor signaling pathway(GO:0010641)
0.1 0.7 GO:0006013 mannose metabolic process(GO:0006013)
0.1 0.7 GO:0045792 negative regulation of cell size(GO:0045792)
0.1 0.3 GO:0061450 synaptic vesicle docking(GO:0016081) trophoblast cell migration(GO:0061450) regulation of trophoblast cell migration(GO:1901163)
0.1 0.3 GO:0032532 regulation of microvillus length(GO:0032532)
0.1 0.5 GO:0007213 G-protein coupled acetylcholine receptor signaling pathway(GO:0007213)
0.1 1.8 GO:0097320 membrane tubulation(GO:0097320)
0.1 0.4 GO:0048254 snoRNA localization(GO:0048254)
0.1 0.9 GO:0007183 SMAD protein complex assembly(GO:0007183)
0.1 0.5 GO:1902035 positive regulation of hematopoietic stem cell proliferation(GO:1902035)
0.1 2.1 GO:0008299 isoprenoid biosynthetic process(GO:0008299)
0.1 0.3 GO:0044805 late nucleophagy(GO:0044805)
0.1 1.1 GO:0006024 glycosaminoglycan biosynthetic process(GO:0006024)
0.1 0.8 GO:0060972 left/right pattern formation(GO:0060972)
0.1 0.2 GO:0006436 tryptophanyl-tRNA aminoacylation(GO:0006436)
0.1 0.9 GO:0048148 behavioral response to cocaine(GO:0048148)
0.1 0.2 GO:0042560 10-formyltetrahydrofolate catabolic process(GO:0009258) folic acid-containing compound catabolic process(GO:0009397) pteridine-containing compound catabolic process(GO:0042560)
0.1 1.6 GO:1901385 regulation of voltage-gated calcium channel activity(GO:1901385)
0.1 0.4 GO:0033198 response to ATP(GO:0033198)
0.1 0.3 GO:0090073 positive regulation of protein homodimerization activity(GO:0090073)
0.1 0.8 GO:0006047 UDP-N-acetylglucosamine metabolic process(GO:0006047)
0.1 0.7 GO:0070050 neuron cellular homeostasis(GO:0070050)
0.1 0.2 GO:0060056 mammary gland involution(GO:0060056)
0.1 0.4 GO:0010804 negative regulation of tumor necrosis factor-mediated signaling pathway(GO:0010804)
0.1 0.4 GO:0030174 regulation of DNA-dependent DNA replication initiation(GO:0030174)
0.1 0.6 GO:2000465 regulation of glycogen (starch) synthase activity(GO:2000465)
0.1 0.4 GO:0090315 negative regulation of protein targeting to membrane(GO:0090315)
0.1 0.2 GO:0018094 protein polyglycylation(GO:0018094)
0.1 0.7 GO:0002227 innate immune response in mucosa(GO:0002227)
0.1 3.1 GO:1904893 negative regulation of JAK-STAT cascade(GO:0046426) negative regulation of STAT cascade(GO:1904893)
0.1 1.4 GO:0034063 stress granule assembly(GO:0034063)
0.1 0.1 GO:0003310 pancreatic A cell differentiation(GO:0003310)
0.1 0.5 GO:0006953 acute-phase response(GO:0006953)
0.1 0.2 GO:0050908 detection of light stimulus involved in visual perception(GO:0050908) detection of light stimulus involved in sensory perception(GO:0050962)
0.1 0.5 GO:0002021 response to dietary excess(GO:0002021)
0.1 0.6 GO:0090503 RNA phosphodiester bond hydrolysis, exonucleolytic(GO:0090503)
0.1 0.5 GO:0048820 hair follicle maturation(GO:0048820)
0.0 3.2 GO:0031638 zymogen activation(GO:0031638)
0.0 0.5 GO:0051601 exocyst localization(GO:0051601)
0.0 0.4 GO:0050860 negative regulation of T cell receptor signaling pathway(GO:0050860)
0.0 0.8 GO:0043486 histone exchange(GO:0043486)
0.0 0.6 GO:2000249 regulation of actin cytoskeleton reorganization(GO:2000249)
0.0 0.5 GO:0035308 negative regulation of dephosphorylation(GO:0035305) negative regulation of protein dephosphorylation(GO:0035308)
0.0 1.2 GO:1902230 negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage(GO:1902230)
0.0 0.7 GO:0051926 negative regulation of calcium ion transport(GO:0051926)
0.0 0.4 GO:0007175 negative regulation of epidermal growth factor-activated receptor activity(GO:0007175)
0.0 0.2 GO:0050716 regulation of interleukin-1 secretion(GO:0050704) regulation of interleukin-1 beta secretion(GO:0050706) positive regulation of interleukin-1 secretion(GO:0050716) positive regulation of interleukin-1 beta secretion(GO:0050718)
0.0 1.2 GO:0016578 histone deubiquitination(GO:0016578)
0.0 0.2 GO:0015817 histidine transport(GO:0015817)
0.0 0.7 GO:0034308 primary alcohol metabolic process(GO:0034308)
0.0 0.9 GO:0061154 endothelial tube morphogenesis(GO:0061154)
0.0 1.1 GO:0045747 positive regulation of Notch signaling pathway(GO:0045747)
0.0 0.2 GO:0006689 ganglioside catabolic process(GO:0006689) oligosaccharide catabolic process(GO:0009313)
0.0 0.4 GO:0032309 icosanoid secretion(GO:0032309)
0.0 0.3 GO:0045954 positive regulation of natural killer cell mediated cytotoxicity(GO:0045954)
0.0 0.2 GO:0018125 peptidyl-cysteine methylation(GO:0018125)
0.0 0.8 GO:0035116 embryonic hindlimb morphogenesis(GO:0035116)
0.0 0.8 GO:0032469 endoplasmic reticulum calcium ion homeostasis(GO:0032469)
0.0 1.2 GO:0007520 myoblast fusion(GO:0007520)
0.0 0.7 GO:0030150 protein import into mitochondrial matrix(GO:0030150)
0.0 0.6 GO:0030252 growth hormone secretion(GO:0030252)
0.0 0.1 GO:0009414 response to water deprivation(GO:0009414)
0.0 1.1 GO:1903846 positive regulation of transforming growth factor beta receptor signaling pathway(GO:0030511) positive regulation of cellular response to transforming growth factor beta stimulus(GO:1903846)
0.0 0.2 GO:0006105 succinate metabolic process(GO:0006105)
0.0 0.2 GO:0016266 O-glycan processing(GO:0016266)
0.0 0.1 GO:2001013 adherens junction maintenance(GO:0034334) epithelial cell proliferation involved in renal tubule morphogenesis(GO:2001013)
0.0 1.0 GO:2000279 negative regulation of DNA biosynthetic process(GO:2000279)
0.0 1.7 GO:0006890 retrograde vesicle-mediated transport, Golgi to ER(GO:0006890)
0.0 0.2 GO:0090336 positive regulation of brown fat cell differentiation(GO:0090336)
0.0 1.3 GO:0035690 cellular response to drug(GO:0035690)
0.0 1.9 GO:0031532 actin cytoskeleton reorganization(GO:0031532)
0.0 0.8 GO:0032011 ARF protein signal transduction(GO:0032011) regulation of ARF protein signal transduction(GO:0032012)
0.0 0.3 GO:0006122 mitochondrial electron transport, ubiquinol to cytochrome c(GO:0006122)
0.0 0.2 GO:1903056 mammillary body development(GO:0021767) mammillary axonal complex development(GO:0061373) melanocyte migration(GO:0097324) positive regulation of lens fiber cell differentiation(GO:1902748) regulation of melanosome organization(GO:1903056)
0.0 0.3 GO:0006471 protein ADP-ribosylation(GO:0006471)
0.0 2.3 GO:0009408 response to heat(GO:0009408)
0.0 1.4 GO:0097031 NADH dehydrogenase complex assembly(GO:0010257) mitochondrial respiratory chain complex I assembly(GO:0032981) mitochondrial respiratory chain complex I biogenesis(GO:0097031)
0.0 1.4 GO:0007032 endosome organization(GO:0007032)
0.0 0.2 GO:0014807 regulation of somitogenesis(GO:0014807)
0.0 0.4 GO:0000054 ribosomal subunit export from nucleus(GO:0000054) ribosome localization(GO:0033750) establishment of ribosome localization(GO:0033753) rRNA-containing ribonucleoprotein complex export from nucleus(GO:0071428)
0.0 0.3 GO:0060999 positive regulation of dendritic spine development(GO:0060999)
0.0 0.1 GO:0032474 otolith morphogenesis(GO:0032474)
0.0 0.1 GO:0060290 transdifferentiation(GO:0060290)
0.0 0.4 GO:0042407 cristae formation(GO:0042407)
0.0 0.1 GO:1900452 regulation of long term synaptic depression(GO:1900452)
0.0 0.4 GO:0060294 cilium movement involved in cell motility(GO:0060294)
0.0 0.5 GO:0006904 vesicle docking involved in exocytosis(GO:0006904)
0.0 0.1 GO:0048149 behavioral response to ethanol(GO:0048149)
0.0 0.2 GO:0034058 endosomal vesicle fusion(GO:0034058)
0.0 1.8 GO:0006888 ER to Golgi vesicle-mediated transport(GO:0006888)
0.0 0.3 GO:0036158 outer dynein arm assembly(GO:0036158)
0.0 0.2 GO:0016255 attachment of GPI anchor to protein(GO:0016255)
0.0 0.3 GO:0031063 regulation of histone deacetylation(GO:0031063)
0.0 0.4 GO:0071712 ER-associated misfolded protein catabolic process(GO:0071712)
0.0 0.1 GO:1903348 positive regulation of bicellular tight junction assembly(GO:1903348)
0.0 0.1 GO:0030647 polyketide metabolic process(GO:0030638) aminoglycoside antibiotic metabolic process(GO:0030647) daunorubicin metabolic process(GO:0044597) doxorubicin metabolic process(GO:0044598)
0.0 0.6 GO:0045746 negative regulation of Notch signaling pathway(GO:0045746)
0.0 0.2 GO:0007288 sperm axoneme assembly(GO:0007288)
0.0 0.1 GO:0071707 immunoglobulin heavy chain V-D-J recombination(GO:0071707)
0.0 0.1 GO:0018202 peptidyl-diphthamide metabolic process(GO:0017182) peptidyl-diphthamide biosynthetic process from peptidyl-histidine(GO:0017183) peptidyl-histidine modification(GO:0018202)
0.0 0.4 GO:0097190 apoptotic signaling pathway(GO:0097190)
0.0 0.2 GO:0035767 endothelial cell chemotaxis(GO:0035767)
0.0 0.3 GO:0010571 positive regulation of nuclear cell cycle DNA replication(GO:0010571)
0.0 0.5 GO:0000028 ribosomal small subunit assembly(GO:0000028)
0.0 0.4 GO:0006198 cAMP catabolic process(GO:0006198)
0.0 1.6 GO:0051865 protein autoubiquitination(GO:0051865)
0.0 0.1 GO:2001032 regulation of double-strand break repair via nonhomologous end joining(GO:2001032)
0.0 1.2 GO:0032543 mitochondrial translation(GO:0032543)
0.0 0.5 GO:0019884 antigen processing and presentation of exogenous antigen(GO:0019884)
0.0 0.0 GO:1902224 cellular ketone body metabolic process(GO:0046950) ketone body metabolic process(GO:1902224)
0.0 0.6 GO:0006909 phagocytosis(GO:0006909)
0.0 0.6 GO:0016601 Rac protein signal transduction(GO:0016601)
0.0 0.1 GO:0009133 nucleoside diphosphate biosynthetic process(GO:0009133)
0.0 0.1 GO:0015015 heparan sulfate proteoglycan biosynthetic process, enzymatic modification(GO:0015015)
0.0 0.5 GO:0061098 positive regulation of protein tyrosine kinase activity(GO:0061098)
0.0 0.4 GO:0033209 tumor necrosis factor-mediated signaling pathway(GO:0033209)
0.0 0.5 GO:0072583 clathrin-mediated endocytosis(GO:0072583)
0.0 0.1 GO:0040010 positive regulation of growth rate(GO:0040010)
0.0 0.3 GO:0016180 snRNA processing(GO:0016180)
0.0 0.9 GO:0033120 positive regulation of RNA splicing(GO:0033120)
0.0 0.5 GO:0001541 ovarian follicle development(GO:0001541)
0.0 0.1 GO:0050853 B cell receptor signaling pathway(GO:0050853)
0.0 1.2 GO:0050731 positive regulation of peptidyl-tyrosine phosphorylation(GO:0050731)
0.0 0.3 GO:0006491 N-glycan processing(GO:0006491)
0.0 0.3 GO:0070536 protein K63-linked deubiquitination(GO:0070536)
0.0 0.2 GO:0003094 glomerular filtration(GO:0003094)
0.0 1.0 GO:1900181 negative regulation of protein localization to nucleus(GO:1900181)
0.0 0.1 GO:0036265 RNA (guanine-N7)-methylation(GO:0036265)
0.0 0.9 GO:0032526 response to retinoic acid(GO:0032526)
0.0 0.3 GO:0046677 response to antibiotic(GO:0046677)
0.0 0.2 GO:0010667 negative regulation of striated muscle cell apoptotic process(GO:0010664) negative regulation of cardiac muscle cell apoptotic process(GO:0010667)
0.0 0.7 GO:0050728 negative regulation of inflammatory response(GO:0050728)
0.0 0.2 GO:0015813 L-glutamate transport(GO:0015813)
0.0 0.2 GO:0016973 poly(A)+ mRNA export from nucleus(GO:0016973)
0.0 0.5 GO:0051897 positive regulation of protein kinase B signaling(GO:0051897)
0.0 0.3 GO:0030488 tRNA methylation(GO:0030488)
0.0 0.8 GO:0042273 ribosomal large subunit biogenesis(GO:0042273)
0.0 1.2 GO:0006364 rRNA processing(GO:0006364)
0.0 0.1 GO:0006668 sphinganine-1-phosphate metabolic process(GO:0006668)
0.0 0.8 GO:0006633 fatty acid biosynthetic process(GO:0006633)
0.0 0.4 GO:1902653 cholesterol biosynthetic process(GO:0006695) secondary alcohol biosynthetic process(GO:1902653)
0.0 0.4 GO:0061077 chaperone-mediated protein folding(GO:0061077)
0.0 0.6 GO:0045454 cell redox homeostasis(GO:0045454)
0.0 0.8 GO:0035383 acyl-CoA metabolic process(GO:0006637) thioester metabolic process(GO:0035383)
0.0 1.1 GO:0007416 synapse assembly(GO:0007416)
0.0 0.1 GO:0009644 response to high light intensity(GO:0009644)
0.0 0.2 GO:0051497 negative regulation of actin filament bundle assembly(GO:0032232) negative regulation of stress fiber assembly(GO:0051497)
0.0 0.6 GO:0006487 protein N-linked glycosylation(GO:0006487)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
2.6 26.2 GO:0045298 tubulin complex(GO:0045298)
2.1 6.4 GO:0016533 cyclin-dependent protein kinase 5 holoenzyme complex(GO:0016533)
1.6 6.4 GO:0032280 symmetric synapse(GO:0032280)
1.2 3.5 GO:1990682 CSF1-CSF1R complex(GO:1990682)
1.0 5.9 GO:0005853 eukaryotic translation elongation factor 1 complex(GO:0005853)
0.8 4.1 GO:0005587 collagen type IV trimer(GO:0005587) network-forming collagen trimer(GO:0098642) collagen network(GO:0098645) basement membrane collagen trimer(GO:0098651)
0.8 3.9 GO:0044316 cone cell pedicle(GO:0044316)
0.7 13.6 GO:0098984 asymmetric synapse(GO:0032279) neuron to neuron synapse(GO:0098984)
0.7 4.0 GO:0005859 muscle myosin complex(GO:0005859)
0.7 0.7 GO:0042105 alpha-beta T cell receptor complex(GO:0042105)
0.6 10.3 GO:0043196 varicosity(GO:0043196)
0.6 7.1 GO:0032426 stereocilium tip(GO:0032426)
0.5 1.6 GO:0098855 HCN channel complex(GO:0098855)
0.5 1.6 GO:0044194 cytolytic granule(GO:0044194)
0.5 1.5 GO:1990769 proximal neuron projection(GO:1990769)
0.5 8.2 GO:0031045 dense core granule(GO:0031045)
0.5 2.4 GO:0032437 cuticular plate(GO:0032437)
0.4 5.2 GO:0043083 synaptic cleft(GO:0043083)
0.4 6.8 GO:0012510 trans-Golgi network transport vesicle membrane(GO:0012510)
0.4 1.6 GO:0031838 haptoglobin-hemoglobin complex(GO:0031838)
0.4 25.4 GO:0009925 basal plasma membrane(GO:0009925)
0.4 3.3 GO:0014731 spectrin-associated cytoskeleton(GO:0014731)
0.4 0.7 GO:0097454 Schwann cell microvillus(GO:0097454)
0.4 1.1 GO:0098835 presynaptic endosome(GO:0098830) presynaptic endocytic zone(GO:0098833) presynaptic endocytic zone membrane(GO:0098835)
0.3 1.0 GO:0044299 C-fiber(GO:0044299)
0.3 15.0 GO:0048786 presynaptic active zone(GO:0048786)
0.3 1.0 GO:0034457 Mpp10 complex(GO:0034457)
0.3 1.2 GO:0030485 smooth muscle contractile fiber(GO:0030485)
0.3 1.8 GO:0071439 clathrin complex(GO:0071439)
0.3 3.5 GO:0038037 G-protein coupled receptor dimeric complex(GO:0038037) G-protein coupled receptor complex(GO:0097648)
0.3 1.2 GO:0090661 box H/ACA telomerase RNP complex(GO:0090661)
0.3 3.8 GO:0017146 NMDA selective glutamate receptor complex(GO:0017146)
0.3 11.0 GO:0005891 voltage-gated calcium channel complex(GO:0005891)
0.3 13.7 GO:0098878 ionotropic glutamate receptor complex(GO:0008328) neurotransmitter receptor complex(GO:0098878)
0.3 1.3 GO:1990357 terminal web(GO:1990357)
0.3 1.1 GO:0032591 dendritic spine membrane(GO:0032591)
0.3 3.1 GO:0002178 palmitoyltransferase complex(GO:0002178)
0.3 0.8 GO:0008091 spectrin(GO:0008091)
0.2 1.0 GO:0016602 CCAAT-binding factor complex(GO:0016602)
0.2 1.2 GO:0030314 junctional membrane complex(GO:0030314)
0.2 1.0 GO:0044301 climbing fiber(GO:0044301) parallel fiber(GO:1990032)
0.2 3.4 GO:0000276 mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276)
0.2 3.4 GO:0016589 NURF complex(GO:0016589)
0.2 1.9 GO:0031315 extrinsic component of mitochondrial outer membrane(GO:0031315)
0.2 0.9 GO:0001651 dense fibrillar component(GO:0001651)
0.2 1.2 GO:0097361 CIA complex(GO:0097361)
0.2 1.8 GO:0001520 outer dense fiber(GO:0001520)
0.2 7.2 GO:0046658 anchored component of plasma membrane(GO:0046658)
0.2 0.7 GO:0044614 nuclear pore cytoplasmic filaments(GO:0044614)
0.2 3.1 GO:0033268 node of Ranvier(GO:0033268)
0.2 2.6 GO:0005832 chaperonin-containing T-complex(GO:0005832)
0.2 2.4 GO:0032584 growth cone membrane(GO:0032584)
0.2 1.7 GO:0044294 dendritic growth cone(GO:0044294)
0.2 0.4 GO:1990812 growth cone filopodium(GO:1990812)
0.2 21.2 GO:0000118 histone deacetylase complex(GO:0000118)
0.2 0.8 GO:1990111 spermatoproteasome complex(GO:1990111)
0.2 2.2 GO:0071598 neuronal ribonucleoprotein granule(GO:0071598)
0.2 3.0 GO:0000145 exocyst(GO:0000145)
0.2 0.6 GO:0043625 delta DNA polymerase complex(GO:0043625)
0.2 4.4 GO:0000242 pericentriolar material(GO:0000242)
0.2 0.5 GO:0043259 laminin-10 complex(GO:0043259)
0.2 0.5 GO:1902937 inward rectifier potassium channel complex(GO:1902937)
0.2 2.6 GO:0005614 interstitial matrix(GO:0005614)
0.2 1.0 GO:0097512 cardiac myofibril(GO:0097512)
0.2 0.7 GO:1990712 HFE-transferrin receptor complex(GO:1990712)
0.2 0.7 GO:0019815 B cell receptor complex(GO:0019815)
0.2 3.5 GO:0012507 ER to Golgi transport vesicle membrane(GO:0012507)
0.2 0.8 GO:1990131 Iml1 complex(GO:1990130) Gtr1-Gtr2 GTPase complex(GO:1990131)
0.2 0.6 GO:0045283 mitochondrial respiratory chain complex II, succinate dehydrogenase complex (ubiquinone)(GO:0005749) succinate dehydrogenase complex (ubiquinone)(GO:0045257) respiratory chain complex II(GO:0045273) succinate dehydrogenase complex(GO:0045281) fumarate reductase complex(GO:0045283)
0.2 1.1 GO:0005638 lamin filament(GO:0005638)
0.1 0.9 GO:0061689 tricellular tight junction(GO:0061689)
0.1 0.9 GO:0070695 FHF complex(GO:0070695)
0.1 1.1 GO:0005787 signal peptidase complex(GO:0005787)
0.1 2.0 GO:0008250 oligosaccharyltransferase complex(GO:0008250)
0.1 4.6 GO:0042734 presynaptic membrane(GO:0042734)
0.1 1.6 GO:0071437 invadopodium(GO:0071437)
0.1 0.5 GO:1990452 Parkin-FBXW7-Cul1 ubiquitin ligase complex(GO:1990452)
0.1 1.0 GO:0005744 mitochondrial inner membrane presequence translocase complex(GO:0005744)
0.1 2.7 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.1 1.4 GO:0005642 annulate lamellae(GO:0005642)
0.1 0.5 GO:0008537 proteasome activator complex(GO:0008537)
0.1 2.8 GO:0038201 TOR complex(GO:0038201)
0.1 2.0 GO:0030134 ER to Golgi transport vesicle(GO:0030134)
0.1 0.7 GO:0005955 calcineurin complex(GO:0005955)
0.1 1.4 GO:0031209 SCAR complex(GO:0031209)
0.1 4.1 GO:0032589 neuron projection membrane(GO:0032589)
0.1 2.1 GO:0016327 apicolateral plasma membrane(GO:0016327)
0.1 0.2 GO:0000125 PCAF complex(GO:0000125)
0.1 0.3 GO:0033596 TSC1-TSC2 complex(GO:0033596)
0.1 1.4 GO:1990635 proximal dendrite(GO:1990635)
0.1 0.7 GO:0097060 synaptic membrane(GO:0097060)
0.1 2.7 GO:0005771 multivesicular body(GO:0005771)
0.1 0.3 GO:1903095 microprocessor complex(GO:0070877) ribonuclease III complex(GO:1903095)
0.1 0.6 GO:0005916 fascia adherens(GO:0005916)
0.1 12.9 GO:0031234 extrinsic component of cytoplasmic side of plasma membrane(GO:0031234)
0.1 2.6 GO:0030137 COPI-coated vesicle(GO:0030137)
0.1 0.9 GO:0070761 pre-snoRNP complex(GO:0070761)
0.1 0.8 GO:0033180 proton-transporting V-type ATPase, V1 domain(GO:0033180)
0.1 1.2 GO:0032045 guanyl-nucleotide exchange factor complex(GO:0032045)
0.1 0.9 GO:0030688 preribosome, small subunit precursor(GO:0030688)
0.1 0.9 GO:0045180 basal cortex(GO:0045180)
0.1 0.8 GO:0000813 ESCRT I complex(GO:0000813)
0.1 1.3 GO:0000124 SAGA complex(GO:0000124)
0.1 1.0 GO:0030057 desmosome(GO:0030057)
0.1 0.4 GO:0032389 MutLalpha complex(GO:0032389)
0.1 2.0 GO:0071565 nBAF complex(GO:0071565)
0.1 1.1 GO:0005797 Golgi medial cisterna(GO:0005797)
0.1 1.0 GO:0005952 cAMP-dependent protein kinase complex(GO:0005952)
0.1 3.5 GO:0031201 SNARE complex(GO:0031201)
0.1 0.6 GO:0042382 paraspeckles(GO:0042382)
0.1 3.4 GO:0016328 lateral plasma membrane(GO:0016328)
0.1 0.4 GO:0000839 Hrd1p ubiquitin ligase ERAD-L complex(GO:0000839)
0.1 0.5 GO:0097452 GAIT complex(GO:0097452)
0.1 0.4 GO:0070937 CRD-mediated mRNA stability complex(GO:0070937)
0.1 0.3 GO:0070876 SOSS complex(GO:0070876)
0.1 0.2 GO:0048179 activin receptor complex(GO:0048179)
0.1 0.6 GO:0071541 eukaryotic translation initiation factor 3 complex, eIF3m(GO:0071541)
0.1 1.0 GO:0030008 TRAPP complex(GO:0030008)
0.1 0.8 GO:0072546 ER membrane protein complex(GO:0072546)
0.1 1.0 GO:0034364 high-density lipoprotein particle(GO:0034364)
0.1 0.6 GO:0097225 sperm midpiece(GO:0097225)
0.1 0.7 GO:0001673 male germ cell nucleus(GO:0001673)
0.1 0.7 GO:0044232 organelle membrane contact site(GO:0044232)
0.1 0.5 GO:0034709 methylosome(GO:0034709)
0.0 0.8 GO:0000930 gamma-tubulin complex(GO:0000930)
0.0 0.4 GO:0005852 eukaryotic translation initiation factor 3 complex(GO:0005852)
0.0 1.0 GO:0005782 peroxisomal matrix(GO:0005782) microbody lumen(GO:0031907)
0.0 0.4 GO:0061617 MICOS complex(GO:0061617)
0.0 6.6 GO:0044309 neuron spine(GO:0044309)
0.0 2.2 GO:0097610 cleavage furrow(GO:0032154) cell surface furrow(GO:0097610)
0.0 1.3 GO:0030687 preribosome, large subunit precursor(GO:0030687)
0.0 0.3 GO:0044300 cerebellar mossy fiber(GO:0044300)
0.0 0.8 GO:0005697 telomerase holoenzyme complex(GO:0005697)
0.0 0.6 GO:0000177 cytoplasmic exosome (RNase complex)(GO:0000177)
0.0 0.4 GO:0036513 Derlin-1 retrotranslocation complex(GO:0036513)
0.0 2.0 GO:0045271 mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
0.0 0.5 GO:0031143 pseudopodium(GO:0031143)
0.0 0.2 GO:0005796 Golgi lumen(GO:0005796)
0.0 3.1 GO:0009986 cell surface(GO:0009986)
0.0 0.5 GO:0031464 Cul4A-RING E3 ubiquitin ligase complex(GO:0031464)
0.0 0.3 GO:0033391 chromatoid body(GO:0033391)
0.0 1.3 GO:0005719 nuclear euchromatin(GO:0005719)
0.0 0.5 GO:0045120 pronucleus(GO:0045120)
0.0 0.3 GO:0000815 ESCRT III complex(GO:0000815)
0.0 0.2 GO:0033263 CORVET complex(GO:0033263)
0.0 0.8 GO:0055038 recycling endosome membrane(GO:0055038)
0.0 0.2 GO:0042588 zymogen granule(GO:0042588)
0.0 0.9 GO:0030992 intraciliary transport particle B(GO:0030992)
0.0 0.5 GO:0031594 neuromuscular junction(GO:0031594)
0.0 2.5 GO:0016363 nuclear matrix(GO:0016363)
0.0 0.2 GO:0042765 GPI-anchor transamidase complex(GO:0042765)
0.0 0.1 GO:0097470 ribbon synapse(GO:0097470)
0.0 2.7 GO:0031225 anchored component of membrane(GO:0031225)
0.0 1.2 GO:0045171 intercellular bridge(GO:0045171)
0.0 1.7 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.0 0.7 GO:0030118 clathrin coat(GO:0030118)
0.0 1.5 GO:0017053 transcriptional repressor complex(GO:0017053)
0.0 1.9 GO:0001725 stress fiber(GO:0001725) contractile actin filament bundle(GO:0097517)
0.0 0.3 GO:0005750 mitochondrial respiratory chain complex III(GO:0005750)
0.0 3.4 GO:0001650 fibrillar center(GO:0001650)
0.0 0.7 GO:0001772 immunological synapse(GO:0001772)
0.0 0.7 GO:0005779 integral component of peroxisomal membrane(GO:0005779)
0.0 0.1 GO:0097129 cyclin D2-CDK4 complex(GO:0097129)
0.0 0.3 GO:0032420 stereocilium(GO:0032420)
0.0 1.4 GO:0005844 polysome(GO:0005844)
0.0 0.8 GO:0030173 integral component of Golgi membrane(GO:0030173) intrinsic component of Golgi membrane(GO:0031228)
0.0 3.8 GO:0000139 Golgi membrane(GO:0000139)
0.0 0.5 GO:0015030 Cajal body(GO:0015030)
0.0 1.0 GO:0005905 clathrin-coated pit(GO:0005905)
0.0 0.8 GO:0005881 cytoplasmic microtubule(GO:0005881)
0.0 0.3 GO:0042555 MCM complex(GO:0042555)
0.0 0.8 GO:0022627 cytosolic small ribosomal subunit(GO:0022627)
0.0 1.5 GO:0000313 organellar ribosome(GO:0000313) mitochondrial ribosome(GO:0005761)
0.0 2.4 GO:0009897 external side of plasma membrane(GO:0009897)
0.0 0.6 GO:0016324 apical plasma membrane(GO:0016324)
0.0 0.5 GO:0005801 cis-Golgi network(GO:0005801)
0.0 0.3 GO:0005847 mRNA cleavage and polyadenylation specificity factor complex(GO:0005847)
0.0 0.1 GO:0043527 tRNA methyltransferase complex(GO:0043527)
0.0 0.2 GO:0042405 nuclear inclusion body(GO:0042405)
0.0 0.2 GO:0019897 extrinsic component of plasma membrane(GO:0019897)
0.0 0.2 GO:0046540 U4/U6 x U5 tri-snRNP complex(GO:0046540)
0.0 0.1 GO:0017119 Golgi transport complex(GO:0017119)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
3.6 25.2 GO:0099609 microtubule lateral binding(GO:0099609)
2.4 16.7 GO:0015198 oligopeptide transporter activity(GO:0015198)
1.9 7.5 GO:0030348 syntaxin-3 binding(GO:0030348)
1.5 4.6 GO:0002153 steroid receptor RNA activator RNA binding(GO:0002153)
1.4 5.6 GO:0061628 H3K27me3 modified histone binding(GO:0061628)
1.3 3.8 GO:0005219 ryanodine-sensitive calcium-release channel activity(GO:0005219)
1.2 7.4 GO:0000155 phosphorelay sensor kinase activity(GO:0000155)
1.2 8.5 GO:0001609 G-protein coupled adenosine receptor activity(GO:0001609) heterotrimeric G-protein binding(GO:0032795)
1.1 5.5 GO:0005030 neurotrophin receptor activity(GO:0005030)
1.0 5.1 GO:0016907 G-protein coupled acetylcholine receptor activity(GO:0016907)
1.0 4.0 GO:0070573 tripeptidyl-peptidase activity(GO:0008240) metallodipeptidase activity(GO:0070573)
1.0 4.8 GO:0070320 inward rectifier potassium channel inhibitor activity(GO:0070320)
0.9 2.8 GO:0004994 somatostatin receptor activity(GO:0004994)
0.9 2.7 GO:0015928 alpha-L-fucosidase activity(GO:0004560) fucosidase activity(GO:0015928)
0.9 3.5 GO:0001639 PLC activating G-protein coupled glutamate receptor activity(GO:0001639) G-protein coupled receptor activity involved in regulation of postsynaptic membrane potential(GO:0099530)
0.8 2.4 GO:0004962 endothelin receptor activity(GO:0004962)
0.8 6.9 GO:0035374 chondroitin sulfate binding(GO:0035374)
0.7 4.3 GO:0015018 galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase activity(GO:0015018)
0.7 2.1 GO:0022833 mechanically-gated ion channel activity(GO:0008381) mechanically gated channel activity(GO:0022833)
0.7 8.7 GO:0047372 acylglycerol lipase activity(GO:0047372)
0.6 7.1 GO:0032036 myosin heavy chain binding(GO:0032036)
0.6 9.4 GO:0045499 chemorepellent activity(GO:0045499)
0.6 1.8 GO:0033829 O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase activity(GO:0033829)
0.6 2.9 GO:0042610 CD8 receptor binding(GO:0042610)
0.6 2.3 GO:0003938 IMP dehydrogenase activity(GO:0003938)
0.5 1.6 GO:0016309 1-phosphatidylinositol-5-phosphate 4-kinase activity(GO:0016309)
0.5 2.6 GO:0003839 gamma-glutamylcyclotransferase activity(GO:0003839)
0.5 1.0 GO:0031871 proteinase activated receptor binding(GO:0031871)
0.5 1.5 GO:0030519 snoRNP binding(GO:0030519)
0.5 2.4 GO:0051371 muscle alpha-actinin binding(GO:0051371)
0.5 2.9 GO:0046912 transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer(GO:0046912)
0.5 0.9 GO:0042134 rRNA primary transcript binding(GO:0042134)
0.5 6.5 GO:0008331 high voltage-gated calcium channel activity(GO:0008331)
0.5 5.0 GO:0022841 potassium ion leak channel activity(GO:0022841)
0.4 1.3 GO:0015232 heme transporter activity(GO:0015232)
0.4 1.3 GO:0043183 vascular endothelial growth factor receptor 1 binding(GO:0043183)
0.4 3.3 GO:0008093 cytoskeletal adaptor activity(GO:0008093)
0.4 1.6 GO:0008332 low voltage-gated calcium channel activity(GO:0008332)
0.4 1.2 GO:0005344 oxygen transporter activity(GO:0005344)
0.4 1.6 GO:0045028 G-protein coupled nucleotide receptor activity(GO:0001608) G-protein coupled purinergic nucleotide receptor activity(GO:0045028)
0.4 1.6 GO:0005222 intracellular cAMP activated cation channel activity(GO:0005222)
0.4 1.6 GO:0031721 haptoglobin binding(GO:0031720) hemoglobin alpha binding(GO:0031721)
0.4 1.1 GO:0019002 GMP binding(GO:0019002)
0.4 1.5 GO:0031800 type 3 metabotropic glutamate receptor binding(GO:0031800)
0.4 1.9 GO:0004105 choline-phosphate cytidylyltransferase activity(GO:0004105)
0.4 1.1 GO:0005128 erythropoietin receptor binding(GO:0005128)
0.4 1.5 GO:0043125 ErbB-3 class receptor binding(GO:0043125)
0.4 4.3 GO:0032050 clathrin heavy chain binding(GO:0032050)
0.4 2.5 GO:0005094 Rho GDP-dissociation inhibitor activity(GO:0005094)
0.3 1.4 GO:0071987 WD40-repeat domain binding(GO:0071987)
0.3 5.8 GO:0005248 voltage-gated sodium channel activity(GO:0005248)
0.3 8.2 GO:0003746 translation elongation factor activity(GO:0003746)
0.3 1.0 GO:0008330 protein tyrosine/threonine phosphatase activity(GO:0008330)
0.3 1.0 GO:0072541 peroxynitrite reductase activity(GO:0072541)
0.3 1.0 GO:0016494 C-X-C chemokine receptor activity(GO:0016494) C-X-C chemokine binding(GO:0019958)
0.3 2.3 GO:0015379 potassium:chloride symporter activity(GO:0015379) potassium ion symporter activity(GO:0022820)
0.3 1.0 GO:0003858 3-hydroxybutyrate dehydrogenase activity(GO:0003858)
0.3 5.3 GO:0008188 neuropeptide receptor activity(GO:0008188)
0.3 3.1 GO:0004972 NMDA glutamate receptor activity(GO:0004972)
0.3 1.8 GO:0004332 fructose-bisphosphate aldolase activity(GO:0004332)
0.3 1.8 GO:0005173 stem cell factor receptor binding(GO:0005173)
0.3 6.4 GO:0005245 voltage-gated calcium channel activity(GO:0005245)
0.3 1.2 GO:0030160 GKAP/Homer scaffold activity(GO:0030160)
0.3 5.8 GO:0005044 scavenger receptor activity(GO:0005044)
0.3 1.9 GO:0001665 alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity(GO:0001665)
0.3 3.2 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.3 1.1 GO:0005315 inorganic phosphate transmembrane transporter activity(GO:0005315)
0.3 1.9 GO:0008499 UDP-galactose:beta-N-acetylglucosamine beta-1,3-galactosyltransferase activity(GO:0008499)
0.3 1.9 GO:0032184 SUMO polymer binding(GO:0032184)
0.3 2.1 GO:0008889 glycerophosphodiester phosphodiesterase activity(GO:0008889)
0.3 0.5 GO:0019870 potassium channel inhibitor activity(GO:0019870)
0.3 7.9 GO:0043539 protein serine/threonine kinase activator activity(GO:0043539)
0.3 1.0 GO:0005093 Rab GDP-dissociation inhibitor activity(GO:0005093)
0.3 2.3 GO:0005007 fibroblast growth factor-activated receptor activity(GO:0005007)
0.3 1.3 GO:0048495 Roundabout binding(GO:0048495)
0.2 1.5 GO:0070567 cytidylyltransferase activity(GO:0070567)
0.2 1.0 GO:0031727 CCR2 chemokine receptor binding(GO:0031727)
0.2 1.9 GO:0016755 transferase activity, transferring amino-acyl groups(GO:0016755)
0.2 0.7 GO:0004069 L-aspartate:2-oxoglutarate aminotransferase activity(GO:0004069)
0.2 6.4 GO:0005227 calcium activated cation channel activity(GO:0005227)
0.2 0.9 GO:0043546 molybdenum ion binding(GO:0030151) molybdopterin cofactor binding(GO:0043546)
0.2 0.9 GO:0004814 arginine-tRNA ligase activity(GO:0004814)
0.2 2.1 GO:0003873 6-phosphofructo-2-kinase activity(GO:0003873) fructose-2,6-bisphosphate 2-phosphatase activity(GO:0004331)
0.2 0.9 GO:0034511 U3 snoRNA binding(GO:0034511)
0.2 6.6 GO:0019707 protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)
0.2 1.6 GO:0031821 G-protein coupled serotonin receptor binding(GO:0031821)
0.2 0.7 GO:0004998 transferrin receptor activity(GO:0004998)
0.2 0.7 GO:0000822 inositol hexakisphosphate binding(GO:0000822)
0.2 0.7 GO:0005001 transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198)
0.2 0.6 GO:0019120 hydrolase activity, acting on acid halide bonds(GO:0016824) hydrolase activity, acting on acid halide bonds, in C-halide compounds(GO:0019120) alkylhalidase activity(GO:0047651)
0.2 0.6 GO:0008177 succinate dehydrogenase (ubiquinone) activity(GO:0008177)
0.2 1.3 GO:0033691 sialic acid binding(GO:0033691)
0.2 1.9 GO:0004416 hydroxyacylglutathione hydrolase activity(GO:0004416)
0.2 3.5 GO:0046933 proton-transporting ATP synthase activity, rotational mechanism(GO:0046933)
0.2 1.8 GO:0048018 receptor agonist activity(GO:0048018)
0.2 0.8 GO:0008410 CoA-transferase activity(GO:0008410)
0.2 0.8 GO:0050220 prostaglandin-E synthase activity(GO:0050220)
0.2 1.0 GO:0004839 ubiquitin activating enzyme activity(GO:0004839)
0.2 1.0 GO:0015450 P-P-bond-hydrolysis-driven protein transmembrane transporter activity(GO:0015450)
0.2 0.8 GO:0034481 chondroitin sulfotransferase activity(GO:0034481)
0.2 3.9 GO:0070300 phosphatidic acid binding(GO:0070300)
0.2 7.1 GO:0030552 cAMP binding(GO:0030552)
0.2 1.0 GO:0005534 galactose binding(GO:0005534)
0.2 0.8 GO:0097109 neuroligin family protein binding(GO:0097109)
0.2 1.3 GO:0003876 AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
0.2 2.5 GO:0005372 water transmembrane transporter activity(GO:0005372)
0.2 4.5 GO:0004385 guanylate kinase activity(GO:0004385)
0.2 1.3 GO:0019869 chloride channel inhibitor activity(GO:0019869)
0.2 1.5 GO:0004767 sphingomyelin phosphodiesterase activity(GO:0004767)
0.2 1.8 GO:0015187 glycine transmembrane transporter activity(GO:0015187)
0.2 7.7 GO:0004715 non-membrane spanning protein tyrosine kinase activity(GO:0004715)
0.2 1.8 GO:0003708 retinoic acid receptor activity(GO:0003708)
0.2 3.0 GO:0035612 AP-2 adaptor complex binding(GO:0035612)
0.2 0.5 GO:0035605 peptidyl-cysteine S-nitrosylase activity(GO:0035605)
0.2 0.5 GO:0004828 serine-tRNA ligase activity(GO:0004828)
0.2 0.5 GO:0070140 isopeptidase activity(GO:0070122) ubiquitin-like protein-specific isopeptidase activity(GO:0070138) SUMO-specific isopeptidase activity(GO:0070140)
0.2 1.2 GO:0032453 histone demethylase activity (H3-K4 specific)(GO:0032453)
0.2 1.0 GO:0004691 cAMP-dependent protein kinase activity(GO:0004691)
0.2 1.2 GO:0015016 [heparan sulfate]-glucosamine N-sulfotransferase activity(GO:0015016)
0.2 1.0 GO:0034186 apolipoprotein A-I binding(GO:0034186)
0.2 1.2 GO:0034513 box H/ACA snoRNA binding(GO:0034513)
0.2 1.8 GO:0004017 adenylate kinase activity(GO:0004017)
0.2 1.0 GO:0043184 vascular endothelial growth factor receptor 2 binding(GO:0043184)
0.2 1.1 GO:0004351 glutamate decarboxylase activity(GO:0004351)
0.2 1.5 GO:0001972 retinoic acid binding(GO:0001972)
0.2 0.5 GO:0036470 tyrosine 3-monooxygenase activator activity(GO:0036470) L-dopa decarboxylase activator activity(GO:0036478)
0.2 1.3 GO:0035033 histone deacetylase regulator activity(GO:0035033)
0.2 0.8 GO:1904288 BAT3 complex binding(GO:1904288)
0.2 0.5 GO:0004667 prostaglandin-D synthase activity(GO:0004667)
0.2 1.5 GO:0042043 neurexin family protein binding(GO:0042043)
0.1 0.9 GO:0031545 peptidyl-proline 4-dioxygenase activity(GO:0031545)
0.1 0.6 GO:2001069 glycogen binding(GO:2001069)
0.1 2.1 GO:0017166 vinculin binding(GO:0017166)
0.1 1.0 GO:0047429 nucleoside-triphosphate diphosphatase activity(GO:0047429)
0.1 2.1 GO:0048407 platelet-derived growth factor binding(GO:0048407)
0.1 0.4 GO:0032137 guanine/thymine mispair binding(GO:0032137)
0.1 0.6 GO:0001733 galactosylceramide sulfotransferase activity(GO:0001733)
0.1 1.9 GO:0008349 MAP kinase kinase kinase kinase activity(GO:0008349)
0.1 4.2 GO:0001786 phosphatidylserine binding(GO:0001786)
0.1 0.4 GO:0015272 ATP-activated inward rectifier potassium channel activity(GO:0015272)
0.1 0.5 GO:0003827 alpha-1,3-mannosylglycoprotein 2-beta-N-acetylglucosaminyltransferase activity(GO:0003827)
0.1 5.4 GO:0030295 protein kinase activator activity(GO:0030295)
0.1 1.4 GO:0031702 angiotensin receptor binding(GO:0031701) type 1 angiotensin receptor binding(GO:0031702)
0.1 1.9 GO:0042809 vitamin D receptor binding(GO:0042809)
0.1 2.1 GO:0071855 neuropeptide receptor binding(GO:0071855)
0.1 0.6 GO:0045545 syndecan binding(GO:0045545)
0.1 0.7 GO:0042805 actinin binding(GO:0042805)
0.1 0.6 GO:0042979 ornithine decarboxylase regulator activity(GO:0042979)
0.1 0.7 GO:0033192 calmodulin-dependent protein phosphatase activity(GO:0033192)
0.1 0.5 GO:0004768 stearoyl-CoA 9-desaturase activity(GO:0004768)
0.1 0.5 GO:0008761 UDP-N-acetylglucosamine 2-epimerase activity(GO:0008761)
0.1 2.5 GO:0017046 peptide hormone binding(GO:0017046)
0.1 0.3 GO:0098973 structural constituent of synapse(GO:0098918) structural constituent of postsynaptic actin cytoskeleton(GO:0098973)
0.1 2.3 GO:0003785 actin monomer binding(GO:0003785)
0.1 1.2 GO:0016701 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen(GO:0016701) oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen(GO:0016702)
0.1 0.9 GO:0000774 adenyl-nucleotide exchange factor activity(GO:0000774)
0.1 0.6 GO:0051525 NFAT protein binding(GO:0051525)
0.1 0.5 GO:0050816 phosphothreonine binding(GO:0050816)
0.1 1.9 GO:0001968 fibronectin binding(GO:0001968)
0.1 2.4 GO:0097602 cullin family protein binding(GO:0097602)
0.1 0.8 GO:0004571 mannosyl-oligosaccharide 1,2-alpha-mannosidase activity(GO:0004571)
0.1 0.2 GO:0005290 L-histidine transmembrane transporter activity(GO:0005290)
0.1 1.2 GO:0003688 DNA replication origin binding(GO:0003688)
0.1 0.8 GO:0032564 dATP binding(GO:0032564)
0.1 0.9 GO:0005545 1-phosphatidylinositol binding(GO:0005545)
0.1 2.3 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.1 0.6 GO:0015197 peptide transporter activity(GO:0015197)
0.1 0.8 GO:0015217 ATP transmembrane transporter activity(GO:0005347) ADP transmembrane transporter activity(GO:0015217)
0.1 2.2 GO:0005544 calcium-dependent phospholipid binding(GO:0005544)
0.1 0.7 GO:0004128 cytochrome-b5 reductase activity, acting on NAD(P)H(GO:0004128)
0.1 2.2 GO:0005086 ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.1 1.0 GO:0048038 quinone binding(GO:0048038)
0.1 3.9 GO:0005518 collagen binding(GO:0005518)
0.1 0.4 GO:0000298 endopolyphosphatase activity(GO:0000298) diphosphoinositol-polyphosphate diphosphatase activity(GO:0008486) bis(5'-adenosyl)-hexaphosphatase activity(GO:0034431) bis(5'-adenosyl)-pentaphosphatase activity(GO:0034432)
0.1 0.6 GO:0070290 N-acylphosphatidylethanolamine-specific phospholipase D activity(GO:0070290)
0.1 0.3 GO:0003976 UDP-N-acetylglucosamine-lysosomal-enzyme N-acetylglucosaminephosphotransferase activity(GO:0003976)
0.1 2.4 GO:0016922 ligand-dependent nuclear receptor binding(GO:0016922)
0.1 2.1 GO:0044183 protein binding involved in protein folding(GO:0044183)
0.1 0.6 GO:0016500 protein-hormone receptor activity(GO:0016500)
0.1 0.5 GO:0034711 inhibin binding(GO:0034711)
0.1 1.4 GO:0008171 O-methyltransferase activity(GO:0008171)
0.1 0.2 GO:0004830 tryptophan-tRNA ligase activity(GO:0004830)
0.1 0.2 GO:0016361 activin receptor activity, type I(GO:0016361) activin-activated receptor activity(GO:0017002)
0.1 0.3 GO:0004035 alkaline phosphatase activity(GO:0004035)
0.1 0.2 GO:0016155 formyltetrahydrofolate dehydrogenase activity(GO:0016155)
0.1 0.3 GO:0004525 ribonuclease III activity(GO:0004525) double-stranded RNA-specific ribonuclease activity(GO:0032296)
0.1 0.3 GO:0003956 NAD(P)+-protein-arginine ADP-ribosyltransferase activity(GO:0003956)
0.1 1.8 GO:0005154 epidermal growth factor receptor binding(GO:0005154)
0.1 0.2 GO:0050347 trans-hexaprenyltranstransferase activity(GO:0000010) trans-octaprenyltranstransferase activity(GO:0050347)
0.1 0.9 GO:0005388 calcium-transporting ATPase activity(GO:0005388)
0.1 2.1 GO:0015175 neutral amino acid transmembrane transporter activity(GO:0015175)
0.1 0.2 GO:0004637 phosphoribosylamine-glycine ligase activity(GO:0004637)
0.1 0.5 GO:0061133 endopeptidase activator activity(GO:0061133)
0.1 1.7 GO:0008376 acetylgalactosaminyltransferase activity(GO:0008376)
0.1 1.0 GO:0050321 tau-protein kinase activity(GO:0050321)
0.1 2.8 GO:0015171 amino acid transmembrane transporter activity(GO:0015171)
0.1 0.7 GO:0030507 spectrin binding(GO:0030507)
0.1 0.4 GO:0017162 aryl hydrocarbon receptor binding(GO:0017162)
0.1 1.0 GO:0003950 NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.1 0.2 GO:0070736 protein-glycine ligase activity(GO:0070735) protein-glycine ligase activity, initiating(GO:0070736)
0.1 0.2 GO:0004647 phosphoserine phosphatase activity(GO:0004647)
0.1 0.3 GO:0052654 branched-chain-amino-acid transaminase activity(GO:0004084) L-leucine transaminase activity(GO:0052654) L-valine transaminase activity(GO:0052655) L-isoleucine transaminase activity(GO:0052656)
0.1 0.4 GO:0001094 TFIID-class transcription factor binding(GO:0001094)
0.1 0.7 GO:0015643 toxic substance binding(GO:0015643)
0.1 0.8 GO:0030898 actin-dependent ATPase activity(GO:0030898)
0.1 5.4 GO:0005089 Rho guanyl-nucleotide exchange factor activity(GO:0005089)
0.1 0.5 GO:1990715 mRNA CDS binding(GO:1990715)
0.1 1.8 GO:0004879 RNA polymerase II transcription factor activity, ligand-activated sequence-specific DNA binding(GO:0004879) transcription factor activity, direct ligand regulated sequence-specific DNA binding(GO:0098531)
0.1 2.8 GO:0035254 glutamate receptor binding(GO:0035254)
0.0 2.6 GO:0004714 transmembrane receptor protein tyrosine kinase activity(GO:0004714)
0.0 4.0 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.0 1.6 GO:0050699 WW domain binding(GO:0050699)
0.0 1.1 GO:0050136 NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.0 0.9 GO:0015035 protein disulfide oxidoreductase activity(GO:0015035)
0.0 0.8 GO:0005528 macrolide binding(GO:0005527) FK506 binding(GO:0005528)
0.0 0.7 GO:0034987 immunoglobulin receptor binding(GO:0034987)
0.0 0.6 GO:0034713 type I transforming growth factor beta receptor binding(GO:0034713)
0.0 0.6 GO:0000339 RNA cap binding(GO:0000339)
0.0 0.4 GO:0097027 ubiquitin-protein transferase activator activity(GO:0097027)
0.0 0.3 GO:0016308 1-phosphatidylinositol-4-phosphate 5-kinase activity(GO:0016308)
0.0 0.6 GO:0004576 oligosaccharyl transferase activity(GO:0004576) dolichyl-diphosphooligosaccharide-protein glycotransferase activity(GO:0004579)
0.0 6.2 GO:0030246 carbohydrate binding(GO:0030246)
0.0 0.5 GO:1990226 histone methyltransferase binding(GO:1990226)
0.0 0.5 GO:0016861 intramolecular oxidoreductase activity, interconverting aldoses and ketoses(GO:0016861)
0.0 1.6 GO:0030374 ligand-dependent nuclear receptor transcription coactivator activity(GO:0030374)
0.0 1.4 GO:0005504 fatty acid binding(GO:0005504)
0.0 2.4 GO:0048365 Rac GTPase binding(GO:0048365)
0.0 0.5 GO:0005078 MAP-kinase scaffold activity(GO:0005078)
0.0 0.4 GO:1904264 ubiquitin protein ligase activity involved in ERAD pathway(GO:1904264)
0.0 0.8 GO:0047617 acyl-CoA hydrolase activity(GO:0047617)
0.0 0.8 GO:0070577 lysine-acetylated histone binding(GO:0070577)
0.0 2.2 GO:0004722 protein serine/threonine phosphatase activity(GO:0004722)
0.0 0.4 GO:0001161 intronic transcription regulatory region sequence-specific DNA binding(GO:0001161)
0.0 0.8 GO:0004298 threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
0.0 0.1 GO:0004127 cytidylate kinase activity(GO:0004127)
0.0 1.1 GO:0004364 glutathione transferase activity(GO:0004364)
0.0 0.4 GO:0019200 carbohydrate kinase activity(GO:0019200)
0.0 1.6 GO:0044325 ion channel binding(GO:0044325)
0.0 0.1 GO:0004769 steroid delta-isomerase activity(GO:0004769)
0.0 0.1 GO:0050692 DBD domain binding(GO:0050692)
0.0 0.3 GO:0070628 proteasome binding(GO:0070628)
0.0 1.2 GO:0031369 translation initiation factor binding(GO:0031369)
0.0 0.3 GO:0008121 ubiquinol-cytochrome-c reductase activity(GO:0008121) oxidoreductase activity, acting on diphenols and related substances as donors(GO:0016679) oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor(GO:0016681)
0.0 0.2 GO:0003923 GPI-anchor transamidase activity(GO:0003923)
0.0 0.4 GO:0042056 chemoattractant activity(GO:0042056)
0.0 0.4 GO:0048156 tau protein binding(GO:0048156)
0.0 0.1 GO:0004534 transcription termination site sequence-specific DNA binding(GO:0001147) transcription termination site DNA binding(GO:0001160) 5'-3' exoribonuclease activity(GO:0004534)
0.0 1.3 GO:0015459 potassium channel regulator activity(GO:0015459)
0.0 0.8 GO:0005246 calcium channel regulator activity(GO:0005246)
0.0 1.9 GO:0008201 heparin binding(GO:0008201)
0.0 0.6 GO:0008157 protein phosphatase 1 binding(GO:0008157)
0.0 1.9 GO:0043021 ribonucleoprotein complex binding(GO:0043021)
0.0 0.1 GO:0008176 tRNA (guanine-N7-)-methyltransferase activity(GO:0008176)
0.0 0.5 GO:0044769 ATPase activity, coupled to transmembrane movement of ions, rotational mechanism(GO:0044769)
0.0 0.6 GO:0071889 14-3-3 protein binding(GO:0071889)
0.0 0.2 GO:0008432 JUN kinase binding(GO:0008432)
0.0 0.6 GO:0005546 phosphatidylinositol-4,5-bisphosphate binding(GO:0005546)
0.0 0.1 GO:0003828 alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity(GO:0003828)
0.0 0.9 GO:0061631 ubiquitin conjugating enzyme activity(GO:0061631)
0.0 0.6 GO:0000175 3'-5'-exoribonuclease activity(GO:0000175) exoribonuclease activity, producing 5'-phosphomonoesters(GO:0016896)
0.0 0.1 GO:0050072 m7G(5')pppN diphosphatase activity(GO:0050072)
0.0 0.2 GO:0046965 retinoid X receptor binding(GO:0046965)
0.0 1.6 GO:0003727 single-stranded RNA binding(GO:0003727)
0.0 0.1 GO:0008467 [heparan sulfate]-glucosamine 3-sulfotransferase 1 activity(GO:0008467)
0.0 0.9 GO:0051082 unfolded protein binding(GO:0051082)
0.0 0.2 GO:0031078 histone deacetylase activity (H3-K14 specific)(GO:0031078) NAD-dependent histone deacetylase activity (H3-K14 specific)(GO:0032041)
0.0 1.8 GO:0047485 protein N-terminus binding(GO:0047485)
0.0 0.3 GO:0016423 tRNA (guanine) methyltransferase activity(GO:0016423)
0.0 0.8 GO:0001221 transcription cofactor binding(GO:0001221)
0.0 0.2 GO:0031489 myosin V binding(GO:0031489)
0.0 0.7 GO:0017137 Rab GTPase binding(GO:0017137)
0.0 1.5 GO:0003705 transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0003705)
0.0 0.1 GO:0004301 epoxide hydrolase activity(GO:0004301)
0.0 0.1 GO:0048256 flap endonuclease activity(GO:0048256)
0.0 0.7 GO:0019003 GDP binding(GO:0019003)
0.0 0.7 GO:0003743 translation initiation factor activity(GO:0003743)
0.0 0.2 GO:0051920 peroxiredoxin activity(GO:0051920)
0.0 0.0 GO:0016833 oxo-acid-lyase activity(GO:0016833)
0.0 1.1 GO:0043130 ubiquitin binding(GO:0043130)
0.0 0.2 GO:0004623 phospholipase A2 activity(GO:0004623)
0.0 0.2 GO:0030332 cyclin binding(GO:0030332)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
1.4 26.0 PID_P38_GAMMA_DELTA_PATHWAY Signaling mediated by p38-gamma and p38-delta
0.4 6.7 PID_ERBB_NETWORK_PATHWAY ErbB receptor signaling network
0.4 1.3 PID_REELIN_PATHWAY Reelin signaling pathway
0.4 4.0 SA_MMP_CYTOKINE_CONNECTION Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.2 5.4 PID_ARF_3PATHWAY Arf1 pathway
0.2 3.6 ST_G_ALPHA_S_PATHWAY G alpha s Pathway
0.2 6.6 PID_RXR_VDR_PATHWAY RXR and RAR heterodimerization with other nuclear receptor
0.2 2.1 PID_NFKAPPAB_ATYPICAL_PATHWAY Atypical NF-kappaB pathway
0.2 8.7 SIG_CD40PATHWAYMAP Genes related to CD40 signaling
0.2 1.2 PID_RET_PATHWAY Signaling events regulated by Ret tyrosine kinase
0.2 6.2 PID_ALK1_PATHWAY ALK1 signaling events
0.2 3.4 PID_INTEGRIN_A9B1_PATHWAY Alpha9 beta1 integrin signaling events
0.2 1.9 PID_VEGF_VEGFR_PATHWAY VEGF and VEGFR signaling network
0.2 6.4 PID_LIS1_PATHWAY Lissencephaly gene (LIS1) in neuronal migration and development
0.1 3.6 PID_KIT_PATHWAY Signaling events mediated by Stem cell factor receptor (c-Kit)
0.1 2.5 PID_FRA_PATHWAY Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.1 3.9 PID_INTEGRIN3_PATHWAY Beta3 integrin cell surface interactions
0.1 5.6 PID_BMP_PATHWAY BMP receptor signaling
0.1 5.9 ST_T_CELL_SIGNAL_TRANSDUCTION T Cell Signal Transduction
0.1 1.6 PID_S1P_S1P1_PATHWAY S1P1 pathway
0.1 3.3 NABA_BASEMENT_MEMBRANES Genes encoding structural components of basement membranes
0.1 4.4 PID_AMB2_NEUTROPHILS_PATHWAY amb2 Integrin signaling
0.1 4.2 PID_FGF_PATHWAY FGF signaling pathway
0.1 10.6 PID_PDGFRB_PATHWAY PDGFR-beta signaling pathway
0.1 0.9 PID_UPA_UPAR_PATHWAY Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling
0.1 3.5 NABA_PROTEOGLYCANS Genes encoding proteoglycans
0.1 2.7 PID_TCPTP_PATHWAY Signaling events mediated by TCPTP
0.1 4.5 PID_AJDISS_2PATHWAY Posttranslational regulation of adherens junction stability and dissassembly
0.1 1.8 PID_CIRCADIAN_PATHWAY Circadian rhythm pathway
0.1 3.8 PID_P38_ALPHA_BETA_DOWNSTREAM_PATHWAY Signaling mediated by p38-alpha and p38-beta
0.1 14.8 NABA_SECRETED_FACTORS Genes encoding secreted soluble factors
0.1 1.5 PID_ANGIOPOIETIN_RECEPTOR_PATHWAY Angiopoietin receptor Tie2-mediated signaling
0.1 1.0 PID_GMCSF_PATHWAY GMCSF-mediated signaling events
0.1 2.2 PID_ATF2_PATHWAY ATF-2 transcription factor network
0.1 0.9 SA_REG_CASCADE_OF_CYCLIN_EXPR Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
0.1 0.6 PID_IL4_2PATHWAY IL4-mediated signaling events
0.1 0.5 PID_NECTIN_PATHWAY Nectin adhesion pathway
0.1 3.7 PID_MYC_REPRESS_PATHWAY Validated targets of C-MYC transcriptional repression
0.1 2.1 PID_HNF3B_PATHWAY FOXA2 and FOXA3 transcription factor networks
0.1 4.7 PID_NOTCH_PATHWAY Notch signaling pathway
0.0 0.8 PID_RAC1_PATHWAY RAC1 signaling pathway
0.0 0.9 PID_HIF1A_PATHWAY Hypoxic and oxygen homeostasis regulation of HIF-1-alpha
0.0 2.0 PID_LKB1_PATHWAY LKB1 signaling events
0.0 0.7 SIG_REGULATION_OF_THE_ACTIN_CYTOSKELETON_BY_RHO_GTPASES Genes related to regulation of the actin cytoskeleton
0.0 0.4 PID_ARF6_DOWNSTREAM_PATHWAY Arf6 downstream pathway
0.0 0.7 PID_EPHA_FWDPATHWAY EPHA forward signaling
0.0 1.1 PID_AP1_PATHWAY AP-1 transcription factor network
0.0 0.7 PID_RB_1PATHWAY Regulation of retinoblastoma protein
0.0 0.8 PID_DELTA_NP63_PATHWAY Validated transcriptional targets of deltaNp63 isoforms
0.0 0.5 PID_FAK_PATHWAY Signaling events mediated by focal adhesion kinase
0.0 0.2 ST_TYPE_I_INTERFERON_PATHWAY Type I Interferon (alpha/beta IFN) Pathway
0.0 0.5 PID_RHOA_PATHWAY RhoA signaling pathway
0.0 1.2 PID_CASPASE_PATHWAY Caspase cascade in apoptosis
0.0 0.1 PID_SYNDECAN_4_PATHWAY Syndecan-4-mediated signaling events
0.0 0.7 PID_ATM_PATHWAY ATM pathway
0.0 1.0 PID_HIF1_TFPATHWAY HIF-1-alpha transcription factor network
0.0 0.2 PID_MYC_PATHWAY C-MYC pathway
0.0 1.0 PID_HDAC_CLASSII_PATHWAY Signaling events mediated by HDAC Class II
0.0 0.2 PID_WNT_NONCANONICAL_PATHWAY Noncanonical Wnt signaling pathway
0.0 0.4 PID_BETA_CATENIN_DEG_PATHWAY Degradation of beta catenin
0.0 0.1 SIG_PIP3_SIGNALING_IN_CARDIAC_MYOCTES Genes related to PIP3 signaling in cardiac myocytes

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
1.9 15.2 REACTOME_TRANSPORT_OF_ORGANIC_ANIONS Genes involved in Transport of organic anions
1.1 25.8 REACTOME_CASPASE_MEDIATED_CLEAVAGE_OF_CYTOSKELETAL_PROTEINS Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.8 10.1 REACTOME_NUCLEOTIDE_LIKE_PURINERGIC_RECEPTORS Genes involved in Nucleotide-like (purinergic) receptors
0.8 7.5 REACTOME_ACETYLCHOLINE_NEUROTRANSMITTER_RELEASE_CYCLE Genes involved in Acetylcholine Neurotransmitter Release Cycle
0.7 5.0 REACTOME_TANDEM_PORE_DOMAIN_POTASSIUM_CHANNELS Genes involved in Tandem pore domain potassium channels
0.6 14.5 REACTOME_HORMONE_SENSITIVE_LIPASE_HSL_MEDIATED_TRIACYLGLYCEROL_HYDROLYSIS Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.4 1.2 REACTOME_THE_ROLE_OF_NEF_IN_HIV1_REPLICATION_AND_DISEASE_PATHOGENESIS Genes involved in The role of Nef in HIV-1 replication and disease pathogenesis
0.4 5.1 REACTOME_AMINE_LIGAND_BINDING_RECEPTORS Genes involved in Amine ligand-binding receptors
0.4 9.1 REACTOME_OTHER_SEMAPHORIN_INTERACTIONS Genes involved in Other semaphorin interactions
0.3 0.3 REACTOME_SIGNALING_BY_NOTCH2 Genes involved in Signaling by NOTCH2
0.3 3.2 REACTOME_CD28_DEPENDENT_VAV1_PATHWAY Genes involved in CD28 dependent Vav1 pathway
0.3 4.2 REACTOME_ACTIVATION_OF_RAC Genes involved in Activation of Rac
0.2 3.1 REACTOME_CLASS_C_3_METABOTROPIC_GLUTAMATE_PHEROMONE_RECEPTORS Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors)
0.2 1.9 REACTOME_FGFR4_LIGAND_BINDING_AND_ACTIVATION Genes involved in FGFR4 ligand binding and activation
0.2 6.9 REACTOME_SIGNALING_BY_BMP Genes involved in Signaling by BMP
0.2 3.7 REACTOME_PURINE_SALVAGE Genes involved in Purine salvage
0.2 7.7 REACTOME_INTERACTION_BETWEEN_L1_AND_ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.2 5.8 REACTOME_RAP1_SIGNALLING Genes involved in Rap1 signalling
0.2 5.6 REACTOME_RAS_ACTIVATION_UOPN_CA2_INFUX_THROUGH_NMDA_RECEPTOR Genes involved in Ras activation uopn Ca2+ infux through NMDA receptor
0.2 3.7 REACTOME_SHC1_EVENTS_IN_ERBB4_SIGNALING Genes involved in SHC1 events in ERBB4 signaling
0.2 1.0 REACTOME_GAMMA_CARBOXYLATION_TRANSPORT_AND_AMINO_TERMINAL_CLEAVAGE_OF_PROTEINS Genes involved in Gamma-carboxylation, transport, and amino-terminal cleavage of proteins
0.2 3.5 REACTOME_FORMATION_OF_ATP_BY_CHEMIOSMOTIC_COUPLING Genes involved in Formation of ATP by chemiosmotic coupling
0.2 2.2 REACTOME_SIGNAL_REGULATORY_PROTEIN_SIRP_FAMILY_INTERACTIONS Genes involved in Signal regulatory protein (SIRP) family interactions
0.2 2.0 REACTOME_GABA_SYNTHESIS_RELEASE_REUPTAKE_AND_DEGRADATION Genes involved in GABA synthesis, release, reuptake and degradation
0.2 1.8 REACTOME_NA_CL_DEPENDENT_NEUROTRANSMITTER_TRANSPORTERS Genes involved in Na+/Cl- dependent neurotransmitter transporters
0.2 3.2 REACTOME_GAP_JUNCTION_DEGRADATION Genes involved in Gap junction degradation
0.2 13.2 REACTOME_PEPTIDE_LIGAND_BINDING_RECEPTORS Genes involved in Peptide ligand-binding receptors
0.2 2.3 REACTOME_PURINE_RIBONUCLEOSIDE_MONOPHOSPHATE_BIOSYNTHESIS Genes involved in Purine ribonucleoside monophosphate biosynthesis
0.2 1.9 REACTOME_VEGF_LIGAND_RECEPTOR_INTERACTIONS Genes involved in VEGF ligand-receptor interactions
0.2 8.2 REACTOME_NCAM_SIGNALING_FOR_NEURITE_OUT_GROWTH Genes involved in NCAM signaling for neurite out-growth
0.1 1.0 REACTOME_ACTIVATION_OF_CHAPERONE_GENES_BY_ATF6_ALPHA Genes involved in Activation of Chaperone Genes by ATF6-alpha
0.1 5.3 REACTOME_ACTIVATED_NOTCH1_TRANSMITS_SIGNAL_TO_THE_NUCLEUS Genes involved in Activated NOTCH1 Transmits Signal to the Nucleus
0.1 4.7 REACTOME_TRAFFICKING_OF_AMPA_RECEPTORS Genes involved in Trafficking of AMPA receptors
0.1 1.3 REACTOME_ACYL_CHAIN_REMODELLING_OF_PG Genes involved in Acyl chain remodelling of PG
0.1 1.2 REACTOME_KERATAN_SULFATE_DEGRADATION Genes involved in Keratan sulfate degradation
0.1 1.1 REACTOME_RECRUITMENT_OF_NUMA_TO_MITOTIC_CENTROSOMES Genes involved in Recruitment of NuMA to mitotic centrosomes
0.1 1.0 REACTOME_APOBEC3G_MEDIATED_RESISTANCE_TO_HIV1_INFECTION Genes involved in APOBEC3G mediated resistance to HIV-1 infection
0.1 8.2 REACTOME_NUCLEAR_RECEPTOR_TRANSCRIPTION_PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.1 2.6 REACTOME_FORMATION_OF_TUBULIN_FOLDING_INTERMEDIATES_BY_CCT_TRIC Genes involved in Formation of tubulin folding intermediates by CCT/TriC
0.1 2.2 REACTOME_ANTIGEN_PRESENTATION_FOLDING_ASSEMBLY_AND_PEPTIDE_LOADING_OF_CLASS_I_MHC Genes involved in Antigen Presentation: Folding, assembly and peptide loading of class I MHC
0.1 4.2 REACTOME_GLYCOLYSIS Genes involved in Glycolysis
0.1 3.6 REACTOME_DARPP_32_EVENTS Genes involved in DARPP-32 events
0.1 1.0 REACTOME_TERMINATION_OF_O_GLYCAN_BIOSYNTHESIS Genes involved in Termination of O-glycan biosynthesis
0.1 0.6 REACTOME_REGULATION_OF_ORNITHINE_DECARBOXYLASE_ODC Genes involved in Regulation of ornithine decarboxylase (ODC)
0.1 1.1 REACTOME_CYTOCHROME_P450_ARRANGED_BY_SUBSTRATE_TYPE Genes involved in Cytochrome P450 - arranged by substrate type
0.1 2.9 REACTOME_O_LINKED_GLYCOSYLATION_OF_MUCINS Genes involved in O-linked glycosylation of mucins
0.1 0.7 REACTOME_PASSIVE_TRANSPORT_BY_AQUAPORINS Genes involved in Passive Transport by Aquaporins
0.1 2.1 REACTOME_POST_NMDA_RECEPTOR_ACTIVATION_EVENTS Genes involved in Post NMDA receptor activation events
0.1 1.5 REACTOME_PRE_NOTCH_PROCESSING_IN_GOLGI Genes involved in Pre-NOTCH Processing in Golgi
0.1 1.4 REACTOME_PTM_GAMMA_CARBOXYLATION_HYPUSINE_FORMATION_AND_ARYLSULFATASE_ACTIVATION Genes involved in PTM: gamma carboxylation, hypusine formation and arylsulfatase activation
0.1 1.2 REACTOME_ZINC_TRANSPORTERS Genes involved in Zinc transporters
0.1 2.7 REACTOME_G_PROTEIN_ACTIVATION Genes involved in G-protein activation
0.1 1.0 REACTOME_HDL_MEDIATED_LIPID_TRANSPORT Genes involved in HDL-mediated lipid transport
0.1 1.2 REACTOME_METABOLISM_OF_POLYAMINES Genes involved in Metabolism of polyamines
0.1 1.6 REACTOME_BASIGIN_INTERACTIONS Genes involved in Basigin interactions
0.1 1.8 REACTOME_CHOLESTEROL_BIOSYNTHESIS Genes involved in Cholesterol biosynthesis
0.1 1.5 REACTOME_INSULIN_SYNTHESIS_AND_PROCESSING Genes involved in Insulin Synthesis and Processing
0.1 1.5 REACTOME_EFFECTS_OF_PIP2_HYDROLYSIS Genes involved in Effects of PIP2 hydrolysis
0.1 0.7 REACTOME_GLUCONEOGENESIS Genes involved in Gluconeogenesis
0.1 1.8 REACTOME_SYNTHESIS_AND_INTERCONVERSION_OF_NUCLEOTIDE_DI_AND_TRIPHOSPHATES Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.1 4.7 REACTOME_POTASSIUM_CHANNELS Genes involved in Potassium Channels
0.1 1.1 REACTOME_SYNTHESIS_SECRETION_AND_DEACYLATION_OF_GHRELIN Genes involved in Synthesis, Secretion, and Deacylation of Ghrelin
0.1 1.2 REACTOME_SULFUR_AMINO_ACID_METABOLISM Genes involved in Sulfur amino acid metabolism
0.1 0.8 REACTOME_CHONDROITIN_SULFATE_BIOSYNTHESIS Genes involved in Chondroitin sulfate biosynthesis
0.1 1.9 REACTOME_A_TETRASACCHARIDE_LINKER_SEQUENCE_IS_REQUIRED_FOR_GAG_SYNTHESIS Genes involved in A tetrasaccharide linker sequence is required for GAG synthesis
0.1 0.6 REACTOME_AMINE_COMPOUND_SLC_TRANSPORTERS Genes involved in Amine compound SLC transporters
0.1 0.9 REACTOME_CYCLIN_A_B1_ASSOCIATED_EVENTS_DURING_G2_M_TRANSITION Genes involved in Cyclin A/B1 associated events during G2/M transition
0.1 0.8 REACTOME_TIE2_SIGNALING Genes involved in Tie2 Signaling
0.1 0.9 REACTOME_OXYGEN_DEPENDENT_PROLINE_HYDROXYLATION_OF_HYPOXIA_INDUCIBLE_FACTOR_ALPHA Genes involved in Oxygen-dependent Proline Hydroxylation of Hypoxia-inducible Factor Alpha
0.1 0.7 REACTOME_SIGNALING_BY_NODAL Genes involved in Signaling by NODAL
0.1 1.6 REACTOME_SYNTHESIS_OF_PIPS_AT_THE_PLASMA_MEMBRANE Genes involved in Synthesis of PIPs at the plasma membrane
0.1 0.9 REACTOME_DOWNREGULATION_OF_TGF_BETA_RECEPTOR_SIGNALING Genes involved in Downregulation of TGF-beta receptor signaling
0.1 1.1 REACTOME_SYNTHESIS_OF_PC Genes involved in Synthesis of PC
0.1 1.5 REACTOME_CYTOSOLIC_TRNA_AMINOACYLATION Genes involved in Cytosolic tRNA aminoacylation
0.0 0.6 REACTOME_NEPHRIN_INTERACTIONS Genes involved in Nephrin interactions
0.0 0.4 REACTOME_PLATELET_CALCIUM_HOMEOSTASIS Genes involved in Platelet calcium homeostasis
0.0 0.8 REACTOME_PROCESSING_OF_INTRONLESS_PRE_MRNAS Genes involved in Processing of Intronless Pre-mRNAs
0.0 1.3 REACTOME_TRANSPORT_TO_THE_GOLGI_AND_SUBSEQUENT_MODIFICATION Genes involved in Transport to the Golgi and subsequent modification
0.0 0.6 REACTOME_POL_SWITCHING Genes involved in Polymerase switching
0.0 2.5 REACTOME_DESTABILIZATION_OF_MRNA_BY_AUF1_HNRNP_D0 Genes involved in Destabilization of mRNA by AUF1 (hnRNP D0)
0.0 1.9 REACTOME_INTEGRIN_CELL_SURFACE_INTERACTIONS Genes involved in Integrin cell surface interactions
0.0 0.8 REACTOME_INSULIN_RECEPTOR_RECYCLING Genes involved in Insulin receptor recycling
0.0 0.2 REACTOME_TRANSPORT_OF_MATURE_MRNA_DERIVED_FROM_AN_INTRONLESS_TRANSCRIPT Genes involved in Transport of Mature mRNA Derived from an Intronless Transcript
0.0 2.0 REACTOME_CIRCADIAN_CLOCK Genes involved in Circadian Clock
0.0 0.9 REACTOME_HS_GAG_BIOSYNTHESIS Genes involved in HS-GAG biosynthesis
0.0 1.1 REACTOME_ASSOCIATION_OF_TRIC_CCT_WITH_TARGET_PROTEINS_DURING_BIOSYNTHESIS Genes involved in Association of TriC/CCT with target proteins during biosynthesis
0.0 1.9 REACTOME_GOLGI_ASSOCIATED_VESICLE_BIOGENESIS Genes involved in Golgi Associated Vesicle Biogenesis
0.0 0.3 REACTOME_CALNEXIN_CALRETICULIN_CYCLE Genes involved in Calnexin/calreticulin cycle
0.0 0.5 REACTOME_HOMOLOGOUS_RECOMBINATION_REPAIR_OF_REPLICATION_INDEPENDENT_DOUBLE_STRAND_BREAKS Genes involved in Homologous recombination repair of replication-independent double-strand breaks
0.0 1.0 REACTOME_TRANSPORT_OF_VITAMINS_NUCLEOSIDES_AND_RELATED_MOLECULES Genes involved in Transport of vitamins, nucleosides, and related molecules
0.0 2.0 REACTOME_RESPIRATORY_ELECTRON_TRANSPORT Genes involved in Respiratory electron transport
0.0 0.5 REACTOME_GPVI_MEDIATED_ACTIVATION_CASCADE Genes involved in GPVI-mediated activation cascade
0.0 1.3 REACTOME_MITOCHONDRIAL_PROTEIN_IMPORT Genes involved in Mitochondrial Protein Import
0.0 0.5 REACTOME_ALPHA_LINOLENIC_ACID_ALA_METABOLISM Genes involved in alpha-linolenic acid (ALA) metabolism
0.0 0.3 REACTOME_PREFOLDIN_MEDIATED_TRANSFER_OF_SUBSTRATE_TO_CCT_TRIC Genes involved in Prefoldin mediated transfer of substrate to CCT/TriC
0.0 1.4 REACTOME_FORMATION_OF_THE_TERNARY_COMPLEX_AND_SUBSEQUENTLY_THE_43S_COMPLEX Genes involved in Formation of the ternary complex, and subsequently, the 43S complex
0.0 0.3 REACTOME_REGULATION_OF_RHEB_GTPASE_ACTIVITY_BY_AMPK Genes involved in Regulation of Rheb GTPase activity by AMPK
0.0 0.7 REACTOME_SMOOTH_MUSCLE_CONTRACTION Genes involved in Smooth Muscle Contraction
0.0 0.5 REACTOME_NGF_SIGNALLING_VIA_TRKA_FROM_THE_PLASMA_MEMBRANE Genes involved in NGF signalling via TRKA from the plasma membrane
0.0 0.4 REACTOME_CGMP_EFFECTS Genes involved in cGMP effects
0.0 0.2 REACTOME_REGULATION_OF_IFNA_SIGNALING Genes involved in Regulation of IFNA signaling
0.0 0.3 REACTOME_UNWINDING_OF_DNA Genes involved in Unwinding of DNA
0.0 1.1 REACTOME_MEIOTIC_SYNAPSIS Genes involved in Meiotic Synapsis
0.0 0.3 REACTOME_BRANCHED_CHAIN_AMINO_ACID_CATABOLISM Genes involved in Branched-chain amino acid catabolism
0.0 0.4 REACTOME_MEIOTIC_RECOMBINATION Genes involved in Meiotic Recombination
0.0 0.2 REACTOME_MRNA_SPLICING_MINOR_PATHWAY Genes involved in mRNA Splicing - Minor Pathway
0.0 0.8 REACTOME_PEPTIDE_CHAIN_ELONGATION Genes involved in Peptide chain elongation