Motif ID: Hinfp

Z-value: 1.386


Transcription factors associated with Hinfp:

Gene SymbolEntrez IDGene Name
Hinfp ENSMUSG00000032119.4 Hinfp

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Hinfpmm10_v2_chr9_-_44305595_44305688-0.096.1e-01Click!


Activity profile for motif Hinfp.

activity profile for motif Hinfp


Sorted Z-values histogram for motif Hinfp

Sorted Z-values for motif Hinfp



Network of associatons between targets according to the STRING database.



First level regulatory network of Hinfp

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr5_-_106458440 8.974 ENSMUST00000086795.6
Barhl2
BarH-like 2 (Drosophila)
chr11_+_80300866 8.677 ENSMUST00000017836.7
Rhbdl3
rhomboid, veinlet-like 3 (Drosophila)
chr13_+_51645232 8.386 ENSMUST00000075853.5
Cks2
CDC28 protein kinase regulatory subunit 2
chr9_+_118478182 8.284 ENSMUST00000111763.1
Eomes
eomesodermin homolog (Xenopus laevis)
chr9_+_118478344 8.010 ENSMUST00000035020.8
Eomes
eomesodermin homolog (Xenopus laevis)
chr17_-_35702297 5.767 ENSMUST00000135078.1
Ddr1
discoidin domain receptor family, member 1
chr2_-_91931675 5.621 ENSMUST00000111309.1
Mdk
midkine
chr19_+_25610533 5.611 ENSMUST00000048935.4
Dmrt3
doublesex and mab-3 related transcription factor 3
chr14_+_65806066 5.407 ENSMUST00000139644.1
Pbk
PDZ binding kinase
chr7_+_122159422 5.026 ENSMUST00000033154.6
Plk1
polo-like kinase 1
chr4_+_52439235 4.901 ENSMUST00000117280.1
ENSMUST00000102915.3
ENSMUST00000142227.1
Smc2


structural maintenance of chromosomes 2


chr1_+_139454747 4.792 ENSMUST00000053364.8
ENSMUST00000097554.3
Aspm

asp (abnormal spindle)-like, microcephaly associated (Drosophila)

chr5_+_33658123 4.597 ENSMUST00000074849.6
ENSMUST00000079534.4
Tacc3

transforming, acidic coiled-coil containing protein 3

chr17_-_35701937 4.518 ENSMUST00000155628.1
Ddr1
discoidin domain receptor family, member 1
chr4_+_97777606 4.387 ENSMUST00000075448.6
ENSMUST00000092532.6
Nfia

nuclear factor I/A

chr3_+_69004711 4.385 ENSMUST00000042901.8
Smc4
structural maintenance of chromosomes 4
chr14_-_8666236 4.383 ENSMUST00000102996.3
4930452B06Rik
RIKEN cDNA 4930452B06 gene
chr5_+_108694222 4.352 ENSMUST00000013633.8
ENSMUST00000112560.3
Fgfrl1

fibroblast growth factor receptor-like 1

chr1_+_191821444 3.972 ENSMUST00000027931.7
Nek2
NIMA (never in mitosis gene a)-related expressed kinase 2
chr2_+_84840612 3.908 ENSMUST00000111625.1
Slc43a1
solute carrier family 43, member 1
chr3_+_69004969 3.844 ENSMUST00000136502.1
ENSMUST00000107803.1
Smc4

structural maintenance of chromosomes 4

chr14_-_21989475 3.811 ENSMUST00000043409.7
Zfp503
zinc finger protein 503
chr6_+_120666388 3.734 ENSMUST00000112686.1
Cecr2
cat eye syndrome chromosome region, candidate 2
chr4_+_128883549 3.631 ENSMUST00000035667.8
Trim62
tripartite motif-containing 62
chr5_-_8422695 3.598 ENSMUST00000171808.1
Dbf4
DBF4 homolog (S. cerevisiae)
chr7_+_67655414 3.592 ENSMUST00000107470.1
Ttc23
tetratricopeptide repeat domain 23
chr3_-_25212720 3.506 ENSMUST00000091289.3
Gm10259
predicted pseudogene 10259
chr5_-_8422582 3.499 ENSMUST00000168500.1
ENSMUST00000002368.9
Dbf4

DBF4 homolog (S. cerevisiae)

chr2_+_124610573 3.494 ENSMUST00000103239.3
ENSMUST00000103240.2
Sema6d

sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6D

chrX_+_120290259 3.397 ENSMUST00000113358.3
ENSMUST00000050239.9
ENSMUST00000113364.3
Pcdh11x


protocadherin 11 X-linked


chr17_-_89910449 3.358 ENSMUST00000086423.4
Gm10184
predicted pseudogene 10184
chr11_+_95337012 3.358 ENSMUST00000037502.6
Fam117a
family with sequence similarity 117, member A
chr2_-_157007015 3.351 ENSMUST00000146413.1
Dsn1
DSN1, MIND kinetochore complex component, homolog (S. cerevisiae)
chr17_+_26917091 3.308 ENSMUST00000078961.4
Kifc5b
kinesin family member C5B
chr4_-_59549314 3.236 ENSMUST00000148331.2
ENSMUST00000030076.5
Ptbp3

polypyrimidine tract binding protein 3

chr7_-_132813528 3.209 ENSMUST00000097999.2
Fam53b
family with sequence similarity 53, member B
chr12_+_116405397 3.196 ENSMUST00000084828.3
Ncapg2
non-SMC condensin II complex, subunit G2
chr8_-_57487801 3.157 ENSMUST00000034022.3
Sap30
sin3 associated polypeptide
chr8_+_127064107 3.054 ENSMUST00000162536.1
ENSMUST00000026921.6
ENSMUST00000162665.1
ENSMUST00000160766.1
ENSMUST00000162602.1
ENSMUST00000162531.1
ENSMUST00000160581.1
ENSMUST00000161355.1
ENSMUST00000159537.1
Pard3








par-3 (partitioning defective 3) homolog (C. elegans)








chr5_+_33658550 3.007 ENSMUST00000152847.1
Tacc3
transforming, acidic coiled-coil containing protein 3
chr6_-_38875923 2.975 ENSMUST00000162359.1
Hipk2
homeodomain interacting protein kinase 2
chr9_-_77544870 2.958 ENSMUST00000183873.1
Lrrc1
leucine rich repeat containing 1
chr17_-_15375969 2.893 ENSMUST00000014917.7
Dll1
delta-like 1 (Drosophila)
chr7_-_116443439 2.885 ENSMUST00000170430.1
Pik3c2a
phosphatidylinositol 3-kinase, C2 domain containing, alpha polypeptide
chr2_+_5845243 2.825 ENSMUST00000127116.1
Nudt5
nudix (nucleoside diphosphate linked moiety X)-type motif 5
chr19_-_4615647 2.750 ENSMUST00000113822.2
Lrfn4
leucine rich repeat and fibronectin type III domain containing 4
chr11_-_88718078 2.743 ENSMUST00000092794.5
Msi2
musashi RNA-binding protein 2
chr5_+_30155243 2.730 ENSMUST00000026841.8
ENSMUST00000123980.1
ENSMUST00000114786.1
Hadhb


hydroxyacyl-Coenzyme A dehydrogenase/3-ketoacyl-Coenzyme A thiolase/enoyl-Coenzyme A hydratase (trifunctional protein), beta subunit


chr5_+_30105161 2.724 ENSMUST00000058045.4
Gareml
GRB2 associated, regulator of MAPK1-like
chr3_+_156562141 2.666 ENSMUST00000175773.1
Negr1
neuronal growth regulator 1
chr4_-_59549243 2.645 ENSMUST00000173699.1
ENSMUST00000173884.1
ENSMUST00000102883.4
ENSMUST00000174586.1
Ptbp3



polypyrimidine tract binding protein 3



chr11_-_106999482 2.632 ENSMUST00000018506.6
Kpna2
karyopherin (importin) alpha 2
chr6_+_47453874 2.623 ENSMUST00000146200.1
Cul1
cullin 1
chr3_+_32708546 2.575 ENSMUST00000029214.7
Actl6a
actin-like 6A
chr11_-_106999369 2.564 ENSMUST00000106768.1
ENSMUST00000144834.1
Kpna2

karyopherin (importin) alpha 2

chr5_+_30155315 2.563 ENSMUST00000114783.1
Hadhb
hydroxyacyl-Coenzyme A dehydrogenase/3-ketoacyl-Coenzyme A thiolase/enoyl-Coenzyme A hydratase (trifunctional protein), beta subunit
chr10_-_83648631 2.523 ENSMUST00000146876.2
ENSMUST00000176294.1
Appl2

adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 2

chr9_+_62838767 2.514 ENSMUST00000034776.6
Cln6
ceroid-lipofuscinosis, neuronal 6
chr1_-_191575534 2.475 ENSMUST00000027933.5
Dtl
denticleless homolog (Drosophila)
chr1_-_91413163 2.432 ENSMUST00000086851.1
Hes6
hairy and enhancer of split 6
chr5_-_30155101 2.403 ENSMUST00000156859.1
Hadha
hydroxyacyl-Coenzyme A dehydrogenase/3-ketoacyl-Coenzyme A thiolase/enoyl-Coenzyme A hydratase (trifunctional protein), alpha subunit
chr8_-_111300222 2.352 ENSMUST00000038739.4
Rfwd3
ring finger and WD repeat domain 3
chr4_-_133967953 2.319 ENSMUST00000102553.4
Hmgn2
high mobility group nucleosomal binding domain 2
chr13_-_98891036 2.270 ENSMUST00000109399.2
Tnpo1
transportin 1
chr9_-_48911067 2.205 ENSMUST00000003826.7
Htr3a
5-hydroxytryptamine (serotonin) receptor 3A
chr11_+_106160850 2.168 ENSMUST00000100326.1
Gm10840
predicted gene 10840
chr12_-_111672290 2.155 ENSMUST00000001304.7
Ckb
creatine kinase, brain
chr17_-_47924400 2.137 ENSMUST00000113263.1
ENSMUST00000097311.2
Foxp4

forkhead box P4

chr17_-_47924460 2.108 ENSMUST00000113262.1
Foxp4
forkhead box P4
chr3_-_95995662 2.091 ENSMUST00000123006.1
Plekho1
pleckstrin homology domain containing, family O member 1
chr3_+_129901419 2.062 ENSMUST00000029626.8
Casp6
caspase 6
chr11_+_70000578 2.059 ENSMUST00000019362.8
Dvl2
dishevelled 2, dsh homolog (Drosophila)
chr1_+_134962553 2.026 ENSMUST00000027687.7
Ube2t
ubiquitin-conjugating enzyme E2T (putative)
chr13_-_98890974 2.026 ENSMUST00000179301.1
ENSMUST00000179271.1
Tnpo1

transportin 1

chr13_-_100650981 2.018 ENSMUST00000022136.6
ENSMUST00000177848.1
Rad17

RAD17 homolog (S. pombe)

chr12_+_51348370 2.001 ENSMUST00000121521.1
G2e3
G2/M-phase specific E3 ubiquitin ligase
chr16_-_84735742 1.984 ENSMUST00000116584.1
Mrpl39
mitochondrial ribosomal protein L39
chr11_-_90002881 1.978 ENSMUST00000020864.8
Pctp
phosphatidylcholine transfer protein
chrX_+_75416669 1.966 ENSMUST00000118428.1
ENSMUST00000114074.1
ENSMUST00000133781.1
Brcc3


BRCA1/BRCA2-containing complex, subunit 3


chr3_+_87919490 1.911 ENSMUST00000019854.6
ENSMUST00000119968.1
Mrpl24

mitochondrial ribosomal protein L24

chr6_+_56714891 1.900 ENSMUST00000031805.8
Avl9
AVL9 homolog (S. cerevisiase)
chr6_-_113419310 1.878 ENSMUST00000147726.1
ENSMUST00000151618.1
ENSMUST00000060634.7
ENSMUST00000129047.1
ENSMUST00000129560.1
ENSMUST00000113092.2
Rpusd3





RNA pseudouridylate synthase domain containing 3





chr16_-_4719148 1.863 ENSMUST00000115851.3
Nmral1
NmrA-like family domain containing 1
chr9_+_3404058 1.809 ENSMUST00000027027.5
Cwf19l2
CWF19-like 2, cell cycle control (S. pombe)
chr16_-_4719078 1.760 ENSMUST00000120056.1
ENSMUST00000074970.7
Nmral1

NmrA-like family domain containing 1

chr3_+_87919563 1.724 ENSMUST00000121920.1
Mrpl24
mitochondrial ribosomal protein L24
chr7_-_92874196 1.721 ENSMUST00000032877.9
4632434I11Rik
RIKEN cDNA 4632434I11 gene
chr2_+_119547697 1.716 ENSMUST00000014221.6
ENSMUST00000119172.1
Chp1

calcineurin-like EF hand protein 1

chrX_+_75416628 1.688 ENSMUST00000033544.7
Brcc3
BRCA1/BRCA2-containing complex, subunit 3
chr3_-_95995835 1.674 ENSMUST00000143485.1
Plekho1
pleckstrin homology domain containing, family O member 1
chr16_-_11176270 1.654 ENSMUST00000037633.8
Zc3h7a
zinc finger CCCH type containing 7 A
chr13_+_24831661 1.654 ENSMUST00000038039.2
Tdp2
tyrosyl-DNA phosphodiesterase 2
chr12_+_51348265 1.653 ENSMUST00000119211.1
G2e3
G2/M-phase specific E3 ubiquitin ligase
chr3_+_87971071 1.636 ENSMUST00000090973.5
Nes
nestin
chr15_+_41788979 1.633 ENSMUST00000170127.1
Oxr1
oxidation resistance 1
chr3_+_96727611 1.621 ENSMUST00000029740.9
Rnf115
ring finger protein 115
chr17_-_25273155 1.621 ENSMUST00000173231.1
Ube2i
ubiquitin-conjugating enzyme E2I
chr13_+_21735055 1.614 ENSMUST00000087714.4
Hist1h4j
histone cluster 1, H4j
chr1_-_128592284 1.599 ENSMUST00000052172.6
ENSMUST00000142893.1
Cxcr4

chemokine (C-X-C motif) receptor 4

chr13_-_29984219 1.572 ENSMUST00000146092.1
E2f3
E2F transcription factor 3
chr5_+_36484578 1.564 ENSMUST00000060100.1
Ccdc96
coiled-coil domain containing 96
chr10_-_9675163 1.564 ENSMUST00000100070.2
Samd5
sterile alpha motif domain containing 5
chr19_-_45560508 1.562 ENSMUST00000026239.6
Poll
polymerase (DNA directed), lambda
chr7_-_4812351 1.560 ENSMUST00000079496.7
Ube2s
ubiquitin-conjugating enzyme E2S
chr3_+_87971129 1.556 ENSMUST00000160694.1
Nes
nestin
chr12_+_51348019 1.544 ENSMUST00000054308.6
G2e3
G2/M-phase specific E3 ubiquitin ligase
chr14_-_57746044 1.512 ENSMUST00000173990.1
ENSMUST00000022531.7
Lats2

large tumor suppressor 2

chrX_+_164419855 1.505 ENSMUST00000112255.1
Piga
phosphatidylinositol glycan anchor biosynthesis, class A
chr11_-_104442232 1.500 ENSMUST00000106977.1
ENSMUST00000106972.1
Kansl1

KAT8 regulatory NSL complex subunit 1

chr4_-_131821516 1.487 ENSMUST00000097860.2
Ptpru
protein tyrosine phosphatase, receptor type, U
chr6_-_8259098 1.480 ENSMUST00000012627.4
Rpa3
replication protein A3
chr14_-_48667508 1.471 ENSMUST00000144465.1
ENSMUST00000133479.1
ENSMUST00000119070.1
ENSMUST00000152018.1
Otx2



orthodenticle homolog 2 (Drosophila)



chr1_+_131527901 1.459 ENSMUST00000068613.4
Fam72a
family with sequence similarity 72, member A
chrX_+_164419782 1.452 ENSMUST00000033754.7
Piga
phosphatidylinositol glycan anchor biosynthesis, class A
chr11_-_70015346 1.436 ENSMUST00000018718.7
ENSMUST00000102574.3
Acadvl

acyl-Coenzyme A dehydrogenase, very long chain

chr2_+_5845017 1.432 ENSMUST00000026927.3
ENSMUST00000179748.1
Nudt5

nudix (nucleoside diphosphate linked moiety X)-type motif 5

chr8_+_57488053 1.418 ENSMUST00000180690.1
2500002B13Rik
RIKEN cDNA 2500002B13 gene
chr12_+_16894894 1.417 ENSMUST00000020904.6
Rock2
Rho-associated coiled-coil containing protein kinase 2
chr14_+_49066495 1.416 ENSMUST00000037473.4
Ap5m1
adaptor-related protein complex 5, mu 1 subunit
chr8_-_25016743 1.388 ENSMUST00000084032.5
Adam9
a disintegrin and metallopeptidase domain 9 (meltrin gamma)
chr9_-_105495130 1.387 ENSMUST00000038118.7
Atp2c1
ATPase, Ca++-sequestering
chr3_+_138143429 1.385 ENSMUST00000040321.6
Trmt10a
tRNA methyltransferase 10A
chr8_-_110997764 1.352 ENSMUST00000040416.7
Ddx19a
DEAD (Asp-Glu-Ala-Asp) box polypeptide 19a
chr3_+_138143483 1.339 ENSMUST00000162864.1
Trmt10a
tRNA methyltransferase 10A
chr4_+_62525369 1.323 ENSMUST00000062145.1
4933430I17Rik
RIKEN cDNA 4933430I17 gene
chr10_-_117376922 1.312 ENSMUST00000177145.1
ENSMUST00000176670.1
Cpsf6

cleavage and polyadenylation specific factor 6

chr19_+_53600377 1.299 ENSMUST00000025930.9
Smc3
structural maintenance of chromosomes 3
chr4_+_116557658 1.296 ENSMUST00000030460.8
Gpbp1l1
GC-rich promoter binding protein 1-like 1
chr15_+_36179299 1.284 ENSMUST00000047348.3
Spag1
sperm associated antigen 1
chr14_+_31001414 1.278 ENSMUST00000022476.7
Glt8d1
glycosyltransferase 8 domain containing 1
chr3_-_69004503 1.271 ENSMUST00000107812.1
Ift80
intraflagellar transport 80
chr13_+_48968287 1.239 ENSMUST00000180775.1
Fam120aos
family with sequence similarity 120A opposite strand
chr9_+_104002546 1.219 ENSMUST00000035167.8
ENSMUST00000117054.1
Nphp3

nephronophthisis 3 (adolescent)

chr10_+_79854618 1.202 ENSMUST00000165704.1
Ptbp1
polypyrimidine tract binding protein 1
chr14_+_31001383 1.198 ENSMUST00000168584.1
Glt8d1
glycosyltransferase 8 domain containing 1
chr10_-_84533968 1.176 ENSMUST00000167671.1
Ckap4
cytoskeleton-associated protein 4
chr17_-_56218881 1.165 ENSMUST00000038794.4
Dpp9
dipeptidylpeptidase 9
chr7_-_30552255 1.164 ENSMUST00000108165.1
ENSMUST00000153594.1
BC053749

cDNA sequence BC053749

chr17_+_28272191 1.161 ENSMUST00000169040.1
Ppard
peroxisome proliferator activator receptor delta
chr9_-_105495475 1.153 ENSMUST00000176036.1
Atp2c1
ATPase, Ca++-sequestering
chr18_-_56562187 1.150 ENSMUST00000171844.2
Aldh7a1
aldehyde dehydrogenase family 7, member A1
chr3_+_146117451 1.149 ENSMUST00000140214.1
Mcoln3
mucolipin 3
chr11_-_29515017 1.143 ENSMUST00000133103.1
ENSMUST00000039900.3
Prorsd1

prolyl-tRNA synthetase domain containing 1

chr10_+_79854658 1.142 ENSMUST00000171599.1
ENSMUST00000095457.4
Ptbp1

polypyrimidine tract binding protein 1

chr4_-_155056784 1.140 ENSMUST00000131173.2
Plch2
phospholipase C, eta 2
chr18_-_56562215 1.135 ENSMUST00000170309.1
Aldh7a1
aldehyde dehydrogenase family 7, member A1
chr18_-_56562261 1.134 ENSMUST00000066208.6
ENSMUST00000172734.1
Aldh7a1

aldehyde dehydrogenase family 7, member A1

chr2_+_163017354 1.132 ENSMUST00000018002.6
ENSMUST00000150396.1
Ift52

intraflagellar transport 52

chr8_-_124751808 1.127 ENSMUST00000055257.5
Fam89a
family with sequence similarity 89, member A
chr17_-_45474839 1.104 ENSMUST00000024731.8
Spats1
spermatogenesis associated, serine-rich 1
chr3_+_40846970 1.101 ENSMUST00000108078.2
3110057O12Rik
RIKEN cDNA 3110057O12 gene
chr9_-_55512156 1.086 ENSMUST00000034866.8
Etfa
electron transferring flavoprotein, alpha polypeptide
chr13_+_72628802 1.083 ENSMUST00000074372.4
Irx2
Iroquois related homeobox 2 (Drosophila)
chr7_-_105787544 1.076 ENSMUST00000078482.5
ENSMUST00000154659.1
Dchs1

dachsous 1 (Drosophila)

chr11_-_102365111 1.058 ENSMUST00000006749.9
Slc4a1
solute carrier family 4 (anion exchanger), member 1
chrY_+_1010543 1.027 ENSMUST00000091197.3
Eif2s3y
eukaryotic translation initiation factor 2, subunit 3, structural gene Y-linked
chr8_-_109693235 1.025 ENSMUST00000034164.4
Ist1
increased sodium tolerance 1 homolog (yeast)
chr14_-_34503323 1.020 ENSMUST00000171343.1
Bmpr1a
bone morphogenetic protein receptor, type 1A
chr13_-_8996004 1.018 ENSMUST00000021574.6
Gtpbp4
GTP binding protein 4
chr10_+_53596936 1.004 ENSMUST00000020004.6
Asf1a
ASF1 anti-silencing function 1 homolog A (S. cerevisiae)
chr1_+_178405881 0.994 ENSMUST00000027775.7
Efcab2
EF-hand calcium binding domain 2
chr1_-_175979114 0.994 ENSMUST00000104983.1
B020018G12Rik
RIKEN cDNA B020018G12 gene
chr1_-_171196229 0.992 ENSMUST00000111332.1
Pcp4l1
Purkinje cell protein 4-like 1
chr17_-_31636631 0.991 ENSMUST00000135425.1
ENSMUST00000151718.1
ENSMUST00000155814.1
Cbs


cystathionine beta-synthase


chr6_-_146577825 0.956 ENSMUST00000032427.8
Asun
asunder, spermatogenesis regulator
chr16_-_11176056 0.948 ENSMUST00000142389.1
ENSMUST00000138185.1
Zc3h7a

zinc finger CCCH type containing 7 A

chr10_+_79927330 0.948 ENSMUST00000105376.1
Arid3a
AT rich interactive domain 3A (BRIGHT-like)
chr8_-_84237042 0.943 ENSMUST00000039480.5
Zswim4
zinc finger SWIM-type containing 4
chr4_+_131873608 0.943 ENSMUST00000053819.3
Srsf4
serine/arginine-rich splicing factor 4
chr11_+_101082565 0.930 ENSMUST00000001806.3
ENSMUST00000107308.3
Coasy

Coenzyme A synthase

chr11_-_58330319 0.918 ENSMUST00000065533.2
Gm9900
predicted gene 9900
chr3_-_96727436 0.894 ENSMUST00000154679.1
Polr3c
polymerase (RNA) III (DNA directed) polypeptide C
chr3_-_138143352 0.878 ENSMUST00000098580.2
Mttp
microsomal triglyceride transfer protein
chr11_+_17211912 0.873 ENSMUST00000046955.6
Wdr92
WD repeat domain 92
chr5_-_150665560 0.869 ENSMUST00000118316.1
N4bp2l2
NEDD4 binding protein 2-like 2
chr13_+_97137937 0.863 ENSMUST00000042084.6
ENSMUST00000160139.1
ENSMUST00000161639.1
ENSMUST00000161913.1
ENSMUST00000161825.1
ENSMUST00000161929.1
ENSMUST00000022170.7
Gfm2






G elongation factor, mitochondrial 2






chr9_-_53248106 0.862 ENSMUST00000065630.6
Ddx10
DEAD (Asp-Glu-Ala-Asp) box polypeptide 10
chr2_+_174330006 0.857 ENSMUST00000109085.1
ENSMUST00000109087.1
ENSMUST00000109084.1
Gnas


GNAS (guanine nucleotide binding protein, alpha stimulating) complex locus


chr15_+_59648350 0.852 ENSMUST00000067543.6
Trib1
tribbles homolog 1 (Drosophila)
chr4_+_15957923 0.842 ENSMUST00000029879.8
ENSMUST00000149069.1
Nbn

nibrin

chr19_+_5601854 0.836 ENSMUST00000025864.4
Rnaseh2c
ribonuclease H2, subunit C
chr5_-_134314637 0.832 ENSMUST00000173504.1
Gtf2i
general transcription factor II I
chr16_-_32003122 0.828 ENSMUST00000023457.5
Senp5
SUMO/sentrin specific peptidase 5
chr4_+_100776664 0.820 ENSMUST00000030257.8
ENSMUST00000097955.2
Cachd1

cache domain containing 1

chr9_-_67043709 0.815 ENSMUST00000113689.1
ENSMUST00000113684.1
Tpm1

tropomyosin 1, alpha

chr5_+_8422831 0.801 ENSMUST00000066921.3
Slc25a40
solute carrier family 25, member 40
chr10_-_59221757 0.800 ENSMUST00000165971.1
Sept10
septin 10
chr2_+_167503089 0.797 ENSMUST00000078050.6
Rnf114
ring finger protein 114
chrX_-_21061981 0.792 ENSMUST00000040628.5
ENSMUST00000115333.2
ENSMUST00000115334.1
Zfp182


zinc finger protein 182


chr19_-_4615453 0.772 ENSMUST00000053597.2
Lrfn4
leucine rich repeat and fibronectin type III domain containing 4
chr5_-_13121766 0.772 ENSMUST00000078246.4
Gm10108
predicted pseudogene 10108
chr12_-_51829525 0.771 ENSMUST00000179265.1
ENSMUST00000042052.8
Hectd1

HECT domain containing 1

chr3_-_96727566 0.755 ENSMUST00000029741.2
Polr3c
polymerase (RNA) III (DNA directed) polypeptide C
chr10_-_40257648 0.753 ENSMUST00000019982.7
Gtf3c6
general transcription factor IIIC, polypeptide 6, alpha
chr18_+_31759817 0.749 ENSMUST00000115808.2
Ammecr1l
AMME chromosomal region gene 1-like
chr3_-_96727453 0.748 ENSMUST00000141377.1
ENSMUST00000125183.1
Polr3c

polymerase (RNA) III (DNA directed) polypeptide C

chr10_-_117376955 0.742 ENSMUST00000069168.6
ENSMUST00000176686.1
Cpsf6

cleavage and polyadenylation specific factor 6

chr10_-_63421739 0.730 ENSMUST00000054760.4
Gm7075
predicted gene 7075
chr17_-_23673825 0.719 ENSMUST00000115490.1
ENSMUST00000047436.4
ENSMUST00000138190.1
ENSMUST00000095579.4
Thoc6



THO complex 6 homolog (Drosophila)



chr10_-_105841323 0.712 ENSMUST00000046638.9
Mettl25
methyltransferase like 25

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
5.4 16.3 GO:0002302 CD8-positive, alpha-beta T cell differentiation involved in immune response(GO:0002302)
1.9 5.6 GO:0030421 defecation(GO:0030421)
1.6 13.1 GO:0010032 meiotic chromosome condensation(GO:0010032)
1.4 7.1 GO:0007089 traversing start control point of mitotic cell cycle(GO:0007089)
1.3 3.8 GO:0070315 G1 to G0 transition involved in cell differentiation(GO:0070315)
1.3 5.0 GO:0040038 polar body extrusion after meiotic divisions(GO:0040038)
1.2 3.6 GO:0035519 protein K29-linked ubiquitination(GO:0035519)
1.2 4.7 GO:0006014 D-ribose metabolic process(GO:0006014)
1.0 4.0 GO:0030997 regulation of centriole-centriole cohesion(GO:0030997)
1.0 2.9 GO:0001757 somite specification(GO:0001757) arterial endothelial cell fate commitment(GO:0060844) blood vessel endothelial cell fate commitment(GO:0060846) endothelial cell fate specification(GO:0060847) Notch signaling pathway involved in arterial endothelial cell fate commitment(GO:0060853) blood vessel endothelial cell fate specification(GO:0097101)
1.0 2.9 GO:0071579 phosphatidylinositol-3-phosphate biosynthetic process(GO:0036092) regulation of zinc ion transport(GO:0071579)
1.0 4.8 GO:0051661 maintenance of centrosome location(GO:0051661)
0.9 3.7 GO:0070537 histone H2A K63-linked deubiquitination(GO:0070537)
0.9 10.3 GO:0061302 smooth muscle cell-matrix adhesion(GO:0061302)
0.8 3.4 GO:0051316 attachment of spindle microtubules to kinetochore involved in meiotic chromosome segregation(GO:0051316)
0.8 3.1 GO:0055071 cellular manganese ion homeostasis(GO:0030026) Golgi calcium ion homeostasis(GO:0032468) manganese ion homeostasis(GO:0055071)
0.7 2.1 GO:0072734 response to staurosporine(GO:0072733) cellular response to staurosporine(GO:0072734)
0.5 2.1 GO:0044340 canonical Wnt signaling pathway involved in regulation of cell proliferation(GO:0044340)
0.5 5.6 GO:0042487 regulation of odontogenesis of dentin-containing tooth(GO:0042487)
0.5 3.1 GO:0003383 apical constriction(GO:0003383)
0.5 1.5 GO:0001827 inner cell mass cell fate commitment(GO:0001827)
0.5 2.9 GO:1903755 regulation of SUMO transferase activity(GO:1903182) positive regulation of SUMO transferase activity(GO:1903755)
0.5 1.4 GO:0034241 positive regulation of macrophage fusion(GO:0034241)
0.4 7.6 GO:0030953 astral microtubule organization(GO:0030953)
0.4 4.3 GO:0006610 ribosomal protein import into nucleus(GO:0006610)
0.4 1.7 GO:0032417 positive regulation of sodium:proton antiporter activity(GO:0032417) negative regulation of calcineurin-NFAT signaling cascade(GO:0070885)
0.4 3.7 GO:0001842 neural fold formation(GO:0001842)
0.4 1.2 GO:0048496 maintenance of organ identity(GO:0048496)
0.4 1.6 GO:0035470 positive regulation of vascular wound healing(GO:0035470) regulation of vascular wound healing(GO:0061043)
0.4 4.4 GO:0060539 diaphragm development(GO:0060539)
0.4 5.9 GO:0043249 erythrocyte maturation(GO:0043249)
0.4 4.2 GO:1901250 regulation of lung goblet cell differentiation(GO:1901249) negative regulation of lung goblet cell differentiation(GO:1901250)
0.4 1.5 GO:0046552 eye photoreceptor cell fate commitment(GO:0042706) photoreceptor cell fate commitment(GO:0046552)
0.4 2.2 GO:0030644 cellular chloride ion homeostasis(GO:0030644)
0.4 1.4 GO:1903347 negative regulation of bicellular tight junction assembly(GO:1903347)
0.3 1.0 GO:0009838 abscission(GO:0009838)
0.3 1.0 GO:0021998 neural plate mediolateral regionalization(GO:0021998) mesoderm structural organization(GO:0048338) paraxial mesoderm structural organization(GO:0048352) regulation of cardiac ventricle development(GO:1904412) positive regulation of cardiac ventricle development(GO:1904414)
0.3 4.4 GO:0072189 ureter development(GO:0072189)
0.3 3.0 GO:0050882 voluntary musculoskeletal movement(GO:0050882)
0.3 1.0 GO:0019343 cysteine biosynthetic process via cystathionine(GO:0019343) cysteine biosynthetic process(GO:0019344)
0.3 4.6 GO:0006607 NLS-bearing protein import into nucleus(GO:0006607)
0.3 1.2 GO:0006776 vitamin A metabolic process(GO:0006776) positive regulation of skeletal muscle tissue regeneration(GO:0043415)
0.3 0.9 GO:0045658 regulation of neutrophil differentiation(GO:0045658) negative regulation of neutrophil differentiation(GO:0045659)
0.3 1.7 GO:0003065 positive regulation of heart rate by epinephrine(GO:0003065)
0.3 1.1 GO:0072272 proximal/distal pattern formation involved in metanephric nephron development(GO:0072272)
0.3 1.1 GO:0072137 condensed mesenchymal cell proliferation(GO:0072137)
0.3 1.6 GO:0070345 negative regulation of fat cell proliferation(GO:0070345)
0.3 1.6 GO:0006287 base-excision repair, gap-filling(GO:0006287)
0.3 0.8 GO:0060708 spongiotrophoblast differentiation(GO:0060708)
0.2 9.0 GO:0001709 cell fate determination(GO:0001709)
0.2 3.8 GO:0051451 myoblast migration(GO:0051451)
0.2 0.7 GO:0006404 RNA import into nucleus(GO:0006404)
0.2 1.1 GO:0035720 intraciliary anterograde transport(GO:0035720)
0.2 0.7 GO:1903225 negative regulation of endodermal cell differentiation(GO:1903225)
0.2 2.5 GO:0007042 lysosomal lumen acidification(GO:0007042)
0.2 2.5 GO:0019985 translesion synthesis(GO:0019985)
0.2 3.5 GO:0001833 inner cell mass cell proliferation(GO:0001833)
0.2 2.0 GO:0033314 mitotic DNA replication checkpoint(GO:0033314)
0.2 0.8 GO:1902037 negative regulation of hematopoietic stem cell differentiation(GO:1902037)
0.2 1.9 GO:0031119 tRNA pseudouridine synthesis(GO:0031119)
0.2 0.4 GO:0031554 regulation of DNA-templated transcription, termination(GO:0031554)
0.2 0.9 GO:0034196 acylglycerol transport(GO:0034196) triglyceride transport(GO:0034197)
0.2 0.3 GO:1903588 negative regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis(GO:1903588)
0.2 0.9 GO:0040032 post-embryonic body morphogenesis(GO:0040032)
0.2 0.5 GO:0038095 Fc-epsilon receptor signaling pathway(GO:0038095)
0.2 0.5 GO:1904760 myofibroblast differentiation(GO:0036446) regulation of myofibroblast differentiation(GO:1904760)
0.2 0.8 GO:0031860 telomeric 3' overhang formation(GO:0031860)
0.2 2.3 GO:0070935 3'-UTR-mediated mRNA stabilization(GO:0070935)
0.2 0.8 GO:0014886 transition between slow and fast fiber(GO:0014886)
0.2 3.6 GO:0032897 negative regulation of viral transcription(GO:0032897)
0.2 1.6 GO:1902083 negative regulation of peptidyl-cysteine S-nitrosylation(GO:1902083)
0.2 1.3 GO:0032876 negative regulation of DNA endoreduplication(GO:0032876) modulation by host of viral release from host cell(GO:0044789) positive regulation by host of viral release from host cell(GO:0044791)
0.2 1.5 GO:0031547 brain-derived neurotrophic factor receptor signaling pathway(GO:0031547)
0.2 1.4 GO:0042760 very long-chain fatty acid catabolic process(GO:0042760)
0.2 3.5 GO:0014912 negative regulation of smooth muscle cell migration(GO:0014912)
0.1 2.4 GO:0036297 interstrand cross-link repair(GO:0036297)
0.1 0.6 GO:1902626 assembly of large subunit precursor of preribosome(GO:1902626)
0.1 1.3 GO:2000051 negative regulation of non-canonical Wnt signaling pathway(GO:2000051)
0.1 0.5 GO:0035269 protein O-linked mannosylation(GO:0035269)
0.1 2.3 GO:0040034 regulation of development, heterochronic(GO:0040034)
0.1 0.6 GO:2001168 regulation of histone H2B ubiquitination(GO:2001166) positive regulation of histone H2B ubiquitination(GO:2001168)
0.1 0.5 GO:0010700 negative regulation of norepinephrine secretion(GO:0010700)
0.1 0.9 GO:0032790 ribosome disassembly(GO:0032790)
0.1 6.3 GO:0045737 positive regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0045737)
0.1 5.4 GO:0070303 negative regulation of stress-activated MAPK cascade(GO:0032873) negative regulation of stress-activated protein kinase signaling cascade(GO:0070303)
0.1 1.5 GO:0043982 histone H4-K5 acetylation(GO:0043981) histone H4-K8 acetylation(GO:0043982)
0.1 8.0 GO:0006635 fatty acid beta-oxidation(GO:0006635)
0.1 0.3 GO:0071921 establishment of sister chromatid cohesion(GO:0034085) cohesin loading(GO:0071921) regulation of cohesin loading(GO:0071922)
0.1 1.6 GO:0043162 ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway(GO:0043162)
0.1 0.7 GO:0046784 viral mRNA export from host cell nucleus(GO:0046784)
0.1 0.7 GO:0042590 antigen processing and presentation of exogenous peptide antigen via MHC class I(GO:0042590)
0.1 2.7 GO:0010960 magnesium ion homeostasis(GO:0010960)
0.1 1.8 GO:0043968 histone H2A acetylation(GO:0043968)
0.1 3.3 GO:0031146 SCF-dependent proteasomal ubiquitin-dependent protein catabolic process(GO:0031146)
0.1 0.3 GO:0031590 wybutosine metabolic process(GO:0031590) wybutosine biosynthetic process(GO:0031591)
0.1 0.5 GO:0036066 protein O-linked fucosylation(GO:0036066)
0.1 0.4 GO:1900095 regulation of dosage compensation by inactivation of X chromosome(GO:1900095)
0.1 2.6 GO:0034723 DNA replication-dependent nucleosome assembly(GO:0006335) DNA replication-dependent nucleosome organization(GO:0034723)
0.1 0.6 GO:0031665 negative regulation of lipopolysaccharide-mediated signaling pathway(GO:0031665)
0.1 0.6 GO:0006451 selenocysteine incorporation(GO:0001514) translational readthrough(GO:0006451)
0.1 5.5 GO:0001824 blastocyst development(GO:0001824)
0.1 0.4 GO:0006290 pyrimidine dimer repair(GO:0006290) activation of JNKK activity(GO:0007256)
0.1 1.1 GO:0014823 response to activity(GO:0014823)
0.1 1.5 GO:0006298 mismatch repair(GO:0006298)
0.1 3.0 GO:0035411 catenin import into nucleus(GO:0035411)
0.1 0.3 GO:0050651 dermatan sulfate proteoglycan biosynthetic process(GO:0050651)
0.1 0.5 GO:0019885 antigen processing and presentation of endogenous peptide antigen via MHC class I(GO:0019885)
0.1 0.8 GO:0016926 protein desumoylation(GO:0016926)
0.1 2.4 GO:0032728 positive regulation of interferon-beta production(GO:0032728)
0.1 0.2 GO:1902268 negative regulation of polyamine transmembrane transport(GO:1902268)
0.1 2.8 GO:0010501 RNA secondary structure unwinding(GO:0010501)
0.1 2.0 GO:0000002 mitochondrial genome maintenance(GO:0000002)
0.1 0.5 GO:1902570 protein localization to nucleolus(GO:1902570)
0.1 3.2 GO:0035914 skeletal muscle cell differentiation(GO:0035914)
0.1 0.5 GO:0002467 germinal center formation(GO:0002467)
0.1 0.7 GO:0015937 coenzyme A biosynthetic process(GO:0015937)
0.1 3.8 GO:0010923 negative regulation of phosphatase activity(GO:0010923)
0.1 0.7 GO:0071044 histone mRNA catabolic process(GO:0071044)
0.1 0.3 GO:0052428 modulation of molecular function in other organism(GO:0044359) negative regulation of molecular function in other organism(GO:0044362) negative regulation of molecular function in other organism involved in symbiotic interaction(GO:0052204) modulation of molecular function in other organism involved in symbiotic interaction(GO:0052205) negative regulation by host of symbiont molecular function(GO:0052405) modification by host of symbiont molecular function(GO:0052428)
0.0 2.0 GO:0043631 mRNA polyadenylation(GO:0006378) RNA polyadenylation(GO:0043631)
0.0 0.7 GO:0090110 cargo loading into COPII-coated vesicle(GO:0090110)
0.0 0.2 GO:0070317 negative regulation of G0 to G1 transition(GO:0070317)
0.0 1.9 GO:0006506 GPI anchor biosynthetic process(GO:0006506)
0.0 0.6 GO:0046855 phosphorylated carbohydrate dephosphorylation(GO:0046838) inositol phosphate dephosphorylation(GO:0046855)
0.0 0.4 GO:0097067 cellular response to thyroid hormone stimulus(GO:0097067)
0.0 0.4 GO:0006301 postreplication repair(GO:0006301)
0.0 1.0 GO:0000079 regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0000079)
0.0 0.1 GO:1905034 regulation of antifungal innate immune response(GO:1905034) negative regulation of antifungal innate immune response(GO:1905035)
0.0 0.4 GO:0048096 chromatin-mediated maintenance of transcription(GO:0048096)
0.0 1.1 GO:0042491 auditory receptor cell differentiation(GO:0042491)
0.0 0.2 GO:0008063 Toll signaling pathway(GO:0008063)
0.0 2.2 GO:0032414 positive regulation of ion transmembrane transporter activity(GO:0032414)
0.0 0.1 GO:1902953 positive regulation of ER to Golgi vesicle-mediated transport(GO:1902953)
0.0 0.4 GO:0046827 positive regulation of protein export from nucleus(GO:0046827)
0.0 0.0 GO:0000966 RNA 5'-end processing(GO:0000966)
0.0 0.8 GO:0006383 transcription from RNA polymerase III promoter(GO:0006383)
0.0 1.1 GO:0034394 protein localization to cell surface(GO:0034394)
0.0 0.2 GO:0001682 tRNA 5'-leader removal(GO:0001682)
0.0 0.6 GO:0070979 protein K11-linked ubiquitination(GO:0070979)
0.0 0.6 GO:0030970 retrograde protein transport, ER to cytosol(GO:0030970)
0.0 1.9 GO:0008203 cholesterol metabolic process(GO:0008203)
0.0 0.3 GO:0060765 regulation of androgen receptor signaling pathway(GO:0060765)
0.0 0.4 GO:0048025 negative regulation of mRNA splicing, via spliceosome(GO:0048025)
0.0 1.3 GO:0032436 positive regulation of proteasomal ubiquitin-dependent protein catabolic process(GO:0032436)
0.0 1.3 GO:0007631 feeding behavior(GO:0007631)
0.0 3.1 GO:0016485 protein processing(GO:0016485)
0.0 0.2 GO:0051044 positive regulation of membrane protein ectodomain proteolysis(GO:0051044)
0.0 1.7 GO:0043524 negative regulation of neuron apoptotic process(GO:0043524)
0.0 0.1 GO:0042407 cristae formation(GO:0042407)
0.0 0.8 GO:0007338 single fertilization(GO:0007338)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
2.6 7.7 GO:0036125 mitochondrial fatty acid beta-oxidation multienzyme complex(GO:0016507) fatty acid beta-oxidation multienzyme complex(GO:0036125)
1.6 16.3 GO:0000796 condensin complex(GO:0000796)
1.3 5.0 GO:0000942 condensed nuclear chromosome outer kinetochore(GO:0000942)
1.0 4.8 GO:0036449 microtubule minus-end(GO:0036449)
0.9 3.7 GO:0090537 CERF complex(GO:0090537)
0.9 3.7 GO:0070552 BRISC complex(GO:0070552)
0.8 3.4 GO:0000939 nuclear MIS12/MIND complex(GO:0000818) condensed chromosome inner kinetochore(GO:0000939)
0.7 2.6 GO:1990452 Parkin-FBXW7-Cul1 ubiquitin ligase complex(GO:1990452)
0.5 3.8 GO:0036195 muscle cell projection(GO:0036194) muscle cell projection membrane(GO:0036195)
0.5 2.9 GO:1990356 sumoylated E2 ligase complex(GO:1990356)
0.4 1.2 GO:0097543 ciliary inversin compartment(GO:0097543)
0.4 3.1 GO:0033269 internode region of axon(GO:0033269)
0.4 2.5 GO:0031465 Cul4B-RING E3 ubiquitin ligase complex(GO:0031465)
0.3 1.3 GO:0034991 nuclear meiotic cohesin complex(GO:0034991)
0.3 1.1 GO:0045251 mitochondrial electron transfer flavoprotein complex(GO:0017133) electron transfer flavoprotein complex(GO:0045251)
0.2 0.7 GO:0005588 collagen type V trimer(GO:0005588)
0.2 3.0 GO:0000506 glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex(GO:0000506)
0.2 2.6 GO:0031011 Ino80 complex(GO:0031011)
0.2 9.0 GO:0000307 cyclin-dependent protein kinase holoenzyme complex(GO:0000307)
0.2 3.2 GO:0016580 Sin3 complex(GO:0016580)
0.1 0.6 GO:0000931 gamma-tubulin large complex(GO:0000931) gamma-tubulin ring complex(GO:0008274)
0.1 0.8 GO:0030870 Mre11 complex(GO:0030870)
0.1 0.8 GO:0032299 ribonuclease H2 complex(GO:0032299)
0.1 1.7 GO:0005862 muscle thin filament tropomyosin(GO:0005862)
0.1 2.9 GO:0005942 phosphatidylinositol 3-kinase complex(GO:0005942)
0.1 0.6 GO:0000839 Hrd1p ubiquitin ligase ERAD-L complex(GO:0000839)
0.1 0.9 GO:0042382 paraspeckles(GO:0042382)
0.1 2.4 GO:0005666 DNA-directed RNA polymerase III complex(GO:0005666)
0.1 1.0 GO:0090543 Flemming body(GO:0090543)
0.1 0.8 GO:0097413 Lewy body(GO:0097413)
0.1 0.8 GO:0000127 transcription factor TFIIIC complex(GO:0000127)
0.1 0.6 GO:0090571 RNA polymerase II transcription repressor complex(GO:0090571)
0.1 1.4 GO:0031233 intrinsic component of external side of plasma membrane(GO:0031233)
0.1 1.4 GO:0005662 DNA replication factor A complex(GO:0005662)
0.1 0.6 GO:0033503 HULC complex(GO:0033503)
0.1 2.2 GO:0005680 anaphase-promoting complex(GO:0005680)
0.1 1.1 GO:0097542 ciliary tip(GO:0097542)
0.1 7.2 GO:0005643 nuclear pore(GO:0005643)
0.1 2.4 GO:0035861 site of double-strand break(GO:0035861)
0.1 3.7 GO:0016235 aggresome(GO:0016235)
0.1 1.4 GO:0031616 spindle pole centrosome(GO:0031616)
0.1 0.7 GO:0000347 THO complex(GO:0000347) THO complex part of transcription export complex(GO:0000445)
0.1 0.5 GO:0033256 I-kappaB/NF-kappaB complex(GO:0033256)
0.1 0.4 GO:0016589 NURF complex(GO:0016589)
0.1 3.4 GO:0005871 kinesin complex(GO:0005871)
0.1 0.3 GO:0005686 U2 snRNP(GO:0005686)
0.1 3.0 GO:0000315 organellar large ribosomal subunit(GO:0000315) mitochondrial large ribosomal subunit(GO:0005762)
0.1 1.3 GO:0030992 intraciliary transport particle B(GO:0030992)
0.1 3.2 GO:0000794 condensed nuclear chromosome(GO:0000794)
0.1 0.9 GO:0031528 microvillus membrane(GO:0031528)
0.1 1.6 GO:0000788 nuclear nucleosome(GO:0000788)
0.1 1.5 GO:0071339 MLL1/2 complex(GO:0044665) MLL1 complex(GO:0071339)
0.0 0.9 GO:0016581 NuRD complex(GO:0016581) CHD-type complex(GO:0090545) nuclear transcriptional repressor complex(GO:0090568)
0.0 2.1 GO:0005788 endoplasmic reticulum lumen(GO:0005788)
0.0 4.5 GO:0044291 cell-cell contact zone(GO:0044291)
0.0 2.2 GO:0097610 cleavage furrow(GO:0032154) cell surface furrow(GO:0097610)
0.0 3.0 GO:0005844 polysome(GO:0005844)
0.0 0.2 GO:0034715 U7 snRNP(GO:0005683) pICln-Sm protein complex(GO:0034715)
0.0 0.2 GO:0005655 nucleolar ribonuclease P complex(GO:0005655)
0.0 0.2 GO:0033061 DNA recombinase mediator complex(GO:0033061)
0.0 1.2 GO:0042645 nucleoid(GO:0009295) mitochondrial nucleoid(GO:0042645)
0.0 0.1 GO:0044530 supraspliceosomal complex(GO:0044530)
0.0 0.8 GO:0008023 transcription elongation factor complex(GO:0008023)
0.0 0.1 GO:0071920 cleavage body(GO:0071920)
0.0 1.7 GO:0000932 cytoplasmic mRNA processing body(GO:0000932)
0.0 0.1 GO:0008622 epsilon DNA polymerase complex(GO:0008622)
0.0 3.3 GO:0031965 nuclear membrane(GO:0031965)
0.0 1.0 GO:0017053 transcriptional repressor complex(GO:0017053)
0.0 0.2 GO:0035631 CD40 receptor complex(GO:0035631)
0.0 0.1 GO:0061617 MICOS complex(GO:0061617)
0.0 1.4 GO:0000781 chromosome, telomeric region(GO:0000781)
0.0 1.0 GO:0005901 caveola(GO:0005901)
0.0 2.3 GO:0030426 growth cone(GO:0030426)
0.0 0.1 GO:0031595 nuclear proteasome complex(GO:0031595)
0.0 0.3 GO:0030687 preribosome, large subunit precursor(GO:0030687)
0.0 0.7 GO:0019005 SCF ubiquitin ligase complex(GO:0019005)
0.0 0.3 GO:0005801 cis-Golgi network(GO:0005801)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
2.1 8.4 GO:0061575 cyclin-dependent protein serine/threonine kinase activator activity(GO:0061575)
1.9 7.8 GO:0016508 long-chain-enoyl-CoA hydratase activity(GO:0016508)
1.4 4.3 GO:0044715 8-oxo-dGDP phosphatase activity(GO:0044715)
1.1 10.3 GO:0038062 protein tyrosine kinase collagen receptor activity(GO:0038062)
0.9 3.4 GO:0008802 betaine-aldehyde dehydrogenase activity(GO:0008802)
0.8 5.0 GO:0010997 anaphase-promoting complex binding(GO:0010997)
0.8 3.1 GO:0015410 manganese-transporting ATPase activity(GO:0015410)
0.6 2.2 GO:0051378 serotonin binding(GO:0051378)
0.5 2.2 GO:0004111 creatine kinase activity(GO:0004111)
0.5 1.6 GO:0016494 C-X-C chemokine receptor activity(GO:0016494)
0.5 4.4 GO:0005007 fibroblast growth factor-activated receptor activity(GO:0005007)
0.5 2.9 GO:0061656 SUMO conjugating enzyme activity(GO:0061656)
0.5 1.4 GO:0017099 very-long-chain-acyl-CoA dehydrogenase activity(GO:0017099)
0.4 2.3 GO:0001069 regulatory region RNA binding(GO:0001069)
0.4 1.2 GO:0016501 prostacyclin receptor activity(GO:0016501)
0.4 3.0 GO:0046790 virion binding(GO:0046790)
0.4 3.2 GO:0031730 CCR5 chemokine receptor binding(GO:0031730)
0.3 2.7 GO:0009019 tRNA (guanine-N1-)-methyltransferase activity(GO:0009019)
0.3 1.0 GO:0098809 nitrite reductase activity(GO:0098809)
0.3 1.3 GO:0036033 mediator complex binding(GO:0036033)
0.3 0.6 GO:0016314 phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase activity(GO:0016314)
0.3 9.5 GO:0008139 nuclear localization sequence binding(GO:0008139)
0.3 0.9 GO:0004140 dephospho-CoA kinase activity(GO:0004140)
0.3 2.9 GO:0035005 1-phosphatidylinositol-4-phosphate 3-kinase activity(GO:0035005)
0.3 0.8 GO:0070139 ubiquitin-like protein-specific endopeptidase activity(GO:0070137) SUMO-specific endopeptidase activity(GO:0070139)
0.3 16.7 GO:0001102 RNA polymerase II activating transcription factor binding(GO:0001102)
0.3 3.0 GO:0017176 phosphatidylinositol N-acetylglucosaminyltransferase activity(GO:0017176)
0.2 0.6 GO:0034211 GTP-dependent protein kinase activity(GO:0034211)
0.2 1.9 GO:0097200 cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:0097200)
0.2 2.1 GO:0003689 DNA clamp loader activity(GO:0003689) protein-DNA loading ATPase activity(GO:0033170)
0.2 0.4 GO:0001160 transcription termination site sequence-specific DNA binding(GO:0001147) transcription termination site DNA binding(GO:0001160)
0.2 2.9 GO:0030957 Tat protein binding(GO:0030957)
0.2 2.0 GO:0008525 phosphatidylcholine transporter activity(GO:0008525)
0.2 3.5 GO:0030215 semaphorin receptor binding(GO:0030215)
0.2 0.5 GO:0004534 5'-3' exoribonuclease activity(GO:0004534)
0.2 1.5 GO:0043995 histone acetyltransferase activity (H4-K5 specific)(GO:0043995) histone acetyltransferase activity (H4-K8 specific)(GO:0043996) histone acetyltransferase activity (H4-K16 specific)(GO:0046972)
0.2 0.5 GO:0031686 A1 adenosine receptor binding(GO:0031686)
0.2 1.6 GO:0051575 5'-deoxyribose-5-phosphate lyase activity(GO:0051575)
0.1 1.0 GO:0098821 BMP receptor activity(GO:0098821)
0.1 2.4 GO:0097371 MDM2/MDM4 family protein binding(GO:0097371)
0.1 2.4 GO:0001056 RNA polymerase III activity(GO:0001056)
0.1 13.3 GO:0003697 single-stranded DNA binding(GO:0003697)
0.1 1.9 GO:0009982 pseudouridine synthase activity(GO:0009982)
0.1 0.4 GO:0000403 Y-form DNA binding(GO:0000403)
0.1 3.2 GO:0043425 bHLH transcription factor binding(GO:0043425)
0.1 7.6 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.1 2.0 GO:0008266 poly(U) RNA binding(GO:0008266)
0.1 1.1 GO:0002161 aminoacyl-tRNA editing activity(GO:0002161)
0.1 3.5 GO:0004407 histone deacetylase activity(GO:0004407)
0.1 0.7 GO:1990825 sequence-specific mRNA binding(GO:1990825)
0.1 0.9 GO:0047391 alkylglycerophosphoethanolamine phosphodiesterase activity(GO:0047391)
0.1 0.5 GO:0034056 estrogen response element binding(GO:0034056)
0.1 3.6 GO:0061631 ubiquitin conjugating enzyme activity(GO:0061631) ubiquitin-like protein conjugating enzyme activity(GO:0061650)
0.1 2.2 GO:0008236 serine-type peptidase activity(GO:0008236)
0.1 0.3 GO:0072542 protein phosphatase activator activity(GO:0072542)
0.1 0.3 GO:0003880 protein C-terminal carboxyl O-methyltransferase activity(GO:0003880)
0.1 2.6 GO:0031492 nucleosomal DNA binding(GO:0031492)
0.1 0.5 GO:0008417 fucosyltransferase activity(GO:0008417)
0.1 3.1 GO:0032266 phosphatidylinositol-3-phosphate binding(GO:0032266)
0.1 0.9 GO:0055106 ubiquitin-protein transferase regulator activity(GO:0055106)
0.1 0.5 GO:0005138 interleukin-6 receptor binding(GO:0005138)
0.1 0.6 GO:0008379 thioredoxin peroxidase activity(GO:0008379)
0.1 3.3 GO:0031593 polyubiquitin binding(GO:0031593)
0.1 1.1 GO:0004435 phosphatidylinositol phospholipase C activity(GO:0004435)
0.1 1.1 GO:0008510 sodium:bicarbonate symporter activity(GO:0008510)
0.1 0.2 GO:0008073 ornithine decarboxylase inhibitor activity(GO:0008073)
0.1 5.6 GO:0008083 growth factor activity(GO:0008083)
0.1 2.1 GO:0005109 frizzled binding(GO:0005109)
0.1 1.4 GO:0043236 laminin binding(GO:0043236)
0.0 12.6 GO:0061630 ubiquitin protein ligase activity(GO:0061630)
0.0 0.6 GO:0048407 platelet-derived growth factor binding(GO:0048407)
0.0 14.2 GO:0001077 transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001077)
0.0 0.5 GO:0045295 gamma-catenin binding(GO:0045295)
0.0 0.4 GO:0016861 intramolecular oxidoreductase activity, interconverting aldoses and ketoses(GO:0016861)
0.0 3.4 GO:0003777 microtubule motor activity(GO:0003777)
0.0 3.8 GO:0008026 ATP-dependent helicase activity(GO:0008026) purine NTP-dependent helicase activity(GO:0070035)
0.0 0.9 GO:0034185 apolipoprotein binding(GO:0034185)
0.0 0.6 GO:0070063 RNA polymerase binding(GO:0070063)
0.0 0.7 GO:0001106 RNA polymerase II transcription corepressor activity(GO:0001106)
0.0 1.1 GO:0008307 structural constituent of muscle(GO:0008307)
0.0 0.2 GO:0051185 coenzyme transporter activity(GO:0051185)
0.0 0.4 GO:0030296 protein tyrosine kinase activator activity(GO:0030296)
0.0 5.9 GO:0001227 transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001227)
0.0 0.8 GO:0051019 mitogen-activated protein kinase binding(GO:0051019)
0.0 12.9 GO:0004674 protein serine/threonine kinase activity(GO:0004674)
0.0 0.3 GO:0008649 rRNA methyltransferase activity(GO:0008649)
0.0 0.2 GO:0031996 thioesterase binding(GO:0031996)
0.0 0.9 GO:0043130 ubiquitin binding(GO:0043130)
0.0 2.2 GO:0001228 transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001228)
0.0 0.3 GO:0019213 deacetylase activity(GO:0019213)
0.0 0.2 GO:0004526 ribonuclease P activity(GO:0004526)
0.0 3.8 GO:0004842 ubiquitin-protein transferase activity(GO:0004842)
0.0 1.5 GO:0004860 protein kinase inhibitor activity(GO:0004860)
0.0 1.1 GO:0050660 flavin adenine dinucleotide binding(GO:0050660)
0.0 1.5 GO:0004725 protein tyrosine phosphatase activity(GO:0004725)
0.0 2.2 GO:0042393 histone binding(GO:0042393)
0.0 0.2 GO:0031491 nucleosome binding(GO:0031491)
0.0 1.7 GO:0017137 Rab GTPase binding(GO:0017137)
0.0 0.1 GO:0036402 proteasome-activating ATPase activity(GO:0036402)
0.0 0.1 GO:0050733 RS domain binding(GO:0050733)
0.0 1.1 GO:0042626 ATPase activity, coupled to transmembrane movement of substances(GO:0042626)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 16.8 PID_IL12_2PATHWAY IL12-mediated signaling events
0.3 8.1 PID_SMAD2_3PATHWAY Regulation of cytoplasmic and nuclear SMAD2/3 signaling
0.2 10.4 PID_AURORA_B_PATHWAY Aurora B signaling
0.2 7.2 PID_SYNDECAN_4_PATHWAY Syndecan-4-mediated signaling events
0.2 9.0 PID_FOXM1_PATHWAY FOXM1 transcription factor network
0.2 1.5 ST_TYPE_I_INTERFERON_PATHWAY Type I Interferon (alpha/beta IFN) Pathway
0.2 6.6 PID_AURORA_A_PATHWAY Aurora A signaling
0.2 4.7 PID_BETA_CATENIN_DEG_PATHWAY Degradation of beta catenin
0.1 1.4 PID_THROMBIN_PAR4_PATHWAY PAR4-mediated thrombin signaling events
0.1 3.8 PID_PS1_PATHWAY Presenilin action in Notch and Wnt signaling
0.1 4.4 PID_HNF3A_PATHWAY FOXA1 transcription factor network
0.1 3.9 PID_ATM_PATHWAY ATM pathway
0.1 1.9 PID_CD40_PATHWAY CD40/CD40L signaling
0.1 1.6 PID_DNA_PK_PATHWAY DNA-PK pathway in nonhomologous end joining
0.1 1.5 PID_MYC_PATHWAY C-MYC pathway
0.1 3.0 PID_P53_REGULATION_PATHWAY p53 pathway
0.1 2.0 PID_FANCONI_PATHWAY Fanconi anemia pathway
0.1 1.5 PID_HIV_NEF_PATHWAY HIV-1 Nef: Negative effector of Fas and TNF-alpha
0.0 3.7 SIG_INSULIN_RECEPTOR_PATHWAY_IN_CARDIAC_MYOCYTES Genes related to the insulin receptor pathway
0.0 1.4 PID_HNF3B_PATHWAY FOXA2 and FOXA3 transcription factor networks
0.0 3.2 PID_SMAD2_3NUCLEAR_PATHWAY Regulation of nuclear SMAD2/3 signaling
0.0 1.6 PID_RB_1PATHWAY Regulation of retinoblastoma protein
0.0 1.8 PID_AVB3_INTEGRIN_PATHWAY Integrins in angiogenesis
0.0 0.5 PID_NCADHERIN_PATHWAY N-cadherin signaling events
0.0 0.6 PID_ARF6_TRAFFICKING_PATHWAY Arf6 trafficking events
0.0 1.6 NABA_ECM_AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 9.1 REACTOME_MITOCHONDRIAL_FATTY_ACID_BETA_OXIDATION Genes involved in Mitochondrial Fatty Acid Beta-Oxidation
0.4 1.6 REACTOME_CDC6_ASSOCIATION_WITH_THE_ORC_ORIGIN_COMPLEX Genes involved in CDC6 association with the ORC:origin complex
0.3 5.0 REACTOME_CYCLIN_A_B1_ASSOCIATED_EVENTS_DURING_G2_M_TRANSITION Genes involved in Cyclin A/B1 associated events during G2/M transition
0.3 10.6 REACTOME_ACTIVATION_OF_ATR_IN_RESPONSE_TO_REPLICATION_STRESS Genes involved in Activation of ATR in response to replication stress
0.3 4.8 REACTOME_DESTABILIZATION_OF_MRNA_BY_TRISTETRAPROLIN_TTP Genes involved in Destabilization of mRNA by Tristetraprolin (TTP)
0.2 6.7 REACTOME_SYNTHESIS_OF_GLYCOSYLPHOSPHATIDYLINOSITOL_GPI Genes involved in Synthesis of glycosylphosphatidylinositol (GPI)
0.2 2.6 REACTOME_PROLACTIN_RECEPTOR_SIGNALING Genes involved in Prolactin receptor signaling
0.2 2.9 REACTOME_RECEPTOR_LIGAND_BINDING_INITIATES_THE_SECOND_PROTEOLYTIC_CLEAVAGE_OF_NOTCH_RECEPTOR Genes involved in Receptor-ligand binding initiates the second proteolytic cleavage of Notch receptor
0.2 2.9 REACTOME_SYNTHESIS_OF_PIPS_AT_THE_EARLY_ENDOSOME_MEMBRANE Genes involved in Synthesis of PIPs at the early endosome membrane
0.2 4.0 REACTOME_APC_CDC20_MEDIATED_DEGRADATION_OF_NEK2A Genes involved in APC-Cdc20 mediated degradation of Nek2A
0.1 3.0 REACTOME_TGF_BETA_RECEPTOR_SIGNALING_IN_EMT_EPITHELIAL_TO_MESENCHYMAL_TRANSITION Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.1 3.6 REACTOME_SIGNALING_BY_HIPPO Genes involved in Signaling by Hippo
0.1 2.2 REACTOME_LIGAND_GATED_ION_CHANNEL_TRANSPORT Genes involved in Ligand-gated ion channel transport
0.1 2.4 REACTOME_RNA_POL_III_CHAIN_ELONGATION Genes involved in RNA Polymerase III Chain Elongation
0.1 2.0 REACTOME_FANCONI_ANEMIA_PATHWAY Genes involved in Fanconi Anemia pathway
0.1 2.1 REACTOME_CASPASE_MEDIATED_CLEAVAGE_OF_CYTOSKELETAL_PROTEINS Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.1 0.8 REACTOME_HOMOLOGOUS_RECOMBINATION_REPAIR_OF_REPLICATION_INDEPENDENT_DOUBLE_STRAND_BREAKS Genes involved in Homologous recombination repair of replication-independent double-strand breaks
0.1 1.6 REACTOME_EARLY_PHASE_OF_HIV_LIFE_CYCLE Genes involved in Early Phase of HIV Life Cycle
0.1 5.8 REACTOME_MEIOTIC_SYNAPSIS Genes involved in Meiotic Synapsis
0.1 6.0 REACTOME_ANTIVIRAL_MECHANISM_BY_IFN_STIMULATED_GENES Genes involved in Antiviral mechanism by IFN-stimulated genes
0.1 1.7 REACTOME_STRIATED_MUSCLE_CONTRACTION Genes involved in Striated Muscle Contraction
0.1 1.2 REACTOME_ANTIGEN_PRESENTATION_FOLDING_ASSEMBLY_AND_PEPTIDE_LOADING_OF_CLASS_I_MHC Genes involved in Antigen Presentation: Folding, assembly and peptide loading of class I MHC
0.1 1.9 REACTOME_SIGNALING_BY_FGFR1_FUSION_MUTANTS Genes involved in Signaling by FGFR1 fusion mutants
0.1 0.9 REACTOME_CHYLOMICRON_MEDIATED_LIPID_TRANSPORT Genes involved in Chylomicron-mediated lipid transport
0.1 0.5 REACTOME_P2Y_RECEPTORS Genes involved in P2Y receptors
0.1 0.7 REACTOME_VITAMIN_B5_PANTOTHENATE_METABOLISM Genes involved in Vitamin B5 (pantothenate) metabolism
0.0 1.7 REACTOME_ION_TRANSPORT_BY_P_TYPE_ATPASES Genes involved in Ion transport by P-type ATPases
0.0 1.4 REACTOME_SEMA4D_INDUCED_CELL_MIGRATION_AND_GROWTH_CONE_COLLAPSE Genes involved in Sema4D induced cell migration and growth-cone collapse
0.0 1.0 REACTOME_SULFUR_AMINO_ACID_METABOLISM Genes involved in Sulfur amino acid metabolism
0.0 6.0 REACTOME_METABOLISM_OF_AMINO_ACIDS_AND_DERIVATIVES Genes involved in Metabolism of amino acids and derivatives
0.0 0.8 REACTOME_METABOLISM_OF_NON_CODING_RNA Genes involved in Metabolism of non-coding RNA
0.0 2.3 REACTOME_MITOTIC_PROMETAPHASE Genes involved in Mitotic Prometaphase
0.0 0.5 REACTOME_SIGNALING_BY_SCF_KIT Genes involved in Signaling by SCF-KIT
0.0 0.9 REACTOME_PROSTACYCLIN_SIGNALLING_THROUGH_PROSTACYCLIN_RECEPTOR Genes involved in Prostacyclin signalling through prostacyclin receptor
0.0 0.5 REACTOME_RIP_MEDIATED_NFKB_ACTIVATION_VIA_DAI Genes involved in RIP-mediated NFkB activation via DAI
0.0 0.2 REACTOME_ACTIVATION_OF_IRF3_IRF7_MEDIATED_BY_TBK1_IKK_EPSILON Genes involved in Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon
0.0 1.2 REACTOME_NUCLEAR_RECEPTOR_TRANSCRIPTION_PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.0 0.4 REACTOME_RNA_POL_I_TRANSCRIPTION_INITIATION Genes involved in RNA Polymerase I Transcription Initiation
0.0 0.7 REACTOME_NCAM1_INTERACTIONS Genes involved in NCAM1 interactions
0.0 0.7 REACTOME_CIRCADIAN_CLOCK Genes involved in Circadian Clock
0.0 0.3 REACTOME_A_TETRASACCHARIDE_LINKER_SEQUENCE_IS_REQUIRED_FOR_GAG_SYNTHESIS Genes involved in A tetrasaccharide linker sequence is required for GAG synthesis
0.0 1.8 REACTOME_ANTIGEN_PROCESSING_UBIQUITINATION_PROTEASOME_DEGRADATION Genes involved in Antigen processing: Ubiquitination & Proteasome degradation