Motif ID: Hinfp
Z-value: 1.386
Transcription factors associated with Hinfp:
Gene Symbol | Entrez ID | Gene Name |
---|---|---|
Hinfp | ENSMUSG00000032119.4 | Hinfp |
Activity-expression correlation:
Gene Symbol | Promoter | Pearson corr. coef. | P-value | Plot |
---|---|---|---|---|
Hinfp | mm10_v2_chr9_-_44305595_44305688 | -0.09 | 6.1e-01 | Click! |
Top targets:
Gene overrepresentation in biological_process category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
5.4 | 16.3 | GO:0002302 | CD8-positive, alpha-beta T cell differentiation involved in immune response(GO:0002302) |
1.9 | 5.6 | GO:0030421 | defecation(GO:0030421) |
1.6 | 13.1 | GO:0010032 | meiotic chromosome condensation(GO:0010032) |
1.4 | 7.1 | GO:0007089 | traversing start control point of mitotic cell cycle(GO:0007089) |
1.3 | 3.8 | GO:0070315 | G1 to G0 transition involved in cell differentiation(GO:0070315) |
1.3 | 5.0 | GO:0040038 | polar body extrusion after meiotic divisions(GO:0040038) |
1.2 | 3.6 | GO:0035519 | protein K29-linked ubiquitination(GO:0035519) |
1.2 | 4.7 | GO:0006014 | D-ribose metabolic process(GO:0006014) |
1.0 | 4.0 | GO:0030997 | regulation of centriole-centriole cohesion(GO:0030997) |
1.0 | 2.9 | GO:0001757 | somite specification(GO:0001757) arterial endothelial cell fate commitment(GO:0060844) blood vessel endothelial cell fate commitment(GO:0060846) endothelial cell fate specification(GO:0060847) Notch signaling pathway involved in arterial endothelial cell fate commitment(GO:0060853) blood vessel endothelial cell fate specification(GO:0097101) |
1.0 | 2.9 | GO:0071579 | phosphatidylinositol-3-phosphate biosynthetic process(GO:0036092) regulation of zinc ion transport(GO:0071579) |
1.0 | 4.8 | GO:0051661 | maintenance of centrosome location(GO:0051661) |
0.9 | 3.7 | GO:0070537 | histone H2A K63-linked deubiquitination(GO:0070537) |
0.9 | 10.3 | GO:0061302 | smooth muscle cell-matrix adhesion(GO:0061302) |
0.8 | 3.4 | GO:0051316 | attachment of spindle microtubules to kinetochore involved in meiotic chromosome segregation(GO:0051316) |
0.8 | 3.1 | GO:0055071 | cellular manganese ion homeostasis(GO:0030026) Golgi calcium ion homeostasis(GO:0032468) manganese ion homeostasis(GO:0055071) |
0.7 | 2.1 | GO:0072734 | response to staurosporine(GO:0072733) cellular response to staurosporine(GO:0072734) |
0.5 | 2.1 | GO:0044340 | canonical Wnt signaling pathway involved in regulation of cell proliferation(GO:0044340) |
0.5 | 5.6 | GO:0042487 | regulation of odontogenesis of dentin-containing tooth(GO:0042487) |
0.5 | 3.1 | GO:0003383 | apical constriction(GO:0003383) |
0.5 | 1.5 | GO:0001827 | inner cell mass cell fate commitment(GO:0001827) |
0.5 | 2.9 | GO:1903755 | regulation of SUMO transferase activity(GO:1903182) positive regulation of SUMO transferase activity(GO:1903755) |
0.5 | 1.4 | GO:0034241 | positive regulation of macrophage fusion(GO:0034241) |
0.4 | 7.6 | GO:0030953 | astral microtubule organization(GO:0030953) |
0.4 | 4.3 | GO:0006610 | ribosomal protein import into nucleus(GO:0006610) |
0.4 | 1.7 | GO:0032417 | positive regulation of sodium:proton antiporter activity(GO:0032417) negative regulation of calcineurin-NFAT signaling cascade(GO:0070885) |
0.4 | 3.7 | GO:0001842 | neural fold formation(GO:0001842) |
0.4 | 1.2 | GO:0048496 | maintenance of organ identity(GO:0048496) |
0.4 | 1.6 | GO:0035470 | positive regulation of vascular wound healing(GO:0035470) regulation of vascular wound healing(GO:0061043) |
0.4 | 4.4 | GO:0060539 | diaphragm development(GO:0060539) |
0.4 | 5.9 | GO:0043249 | erythrocyte maturation(GO:0043249) |
0.4 | 4.2 | GO:1901250 | regulation of lung goblet cell differentiation(GO:1901249) negative regulation of lung goblet cell differentiation(GO:1901250) |
0.4 | 1.5 | GO:0046552 | eye photoreceptor cell fate commitment(GO:0042706) photoreceptor cell fate commitment(GO:0046552) |
0.4 | 2.2 | GO:0030644 | cellular chloride ion homeostasis(GO:0030644) |
0.4 | 1.4 | GO:1903347 | negative regulation of bicellular tight junction assembly(GO:1903347) |
0.3 | 1.0 | GO:0009838 | abscission(GO:0009838) |
0.3 | 1.0 | GO:0021998 | neural plate mediolateral regionalization(GO:0021998) mesoderm structural organization(GO:0048338) paraxial mesoderm structural organization(GO:0048352) regulation of cardiac ventricle development(GO:1904412) positive regulation of cardiac ventricle development(GO:1904414) |
0.3 | 4.4 | GO:0072189 | ureter development(GO:0072189) |
0.3 | 3.0 | GO:0050882 | voluntary musculoskeletal movement(GO:0050882) |
0.3 | 1.0 | GO:0019343 | cysteine biosynthetic process via cystathionine(GO:0019343) cysteine biosynthetic process(GO:0019344) |
0.3 | 4.6 | GO:0006607 | NLS-bearing protein import into nucleus(GO:0006607) |
0.3 | 1.2 | GO:0006776 | vitamin A metabolic process(GO:0006776) positive regulation of skeletal muscle tissue regeneration(GO:0043415) |
0.3 | 0.9 | GO:0045658 | regulation of neutrophil differentiation(GO:0045658) negative regulation of neutrophil differentiation(GO:0045659) |
0.3 | 1.7 | GO:0003065 | positive regulation of heart rate by epinephrine(GO:0003065) |
0.3 | 1.1 | GO:0072272 | proximal/distal pattern formation involved in metanephric nephron development(GO:0072272) |
0.3 | 1.1 | GO:0072137 | condensed mesenchymal cell proliferation(GO:0072137) |
0.3 | 1.6 | GO:0070345 | negative regulation of fat cell proliferation(GO:0070345) |
0.3 | 1.6 | GO:0006287 | base-excision repair, gap-filling(GO:0006287) |
0.3 | 0.8 | GO:0060708 | spongiotrophoblast differentiation(GO:0060708) |
0.2 | 9.0 | GO:0001709 | cell fate determination(GO:0001709) |
0.2 | 3.8 | GO:0051451 | myoblast migration(GO:0051451) |
0.2 | 0.7 | GO:0006404 | RNA import into nucleus(GO:0006404) |
0.2 | 1.1 | GO:0035720 | intraciliary anterograde transport(GO:0035720) |
0.2 | 0.7 | GO:1903225 | negative regulation of endodermal cell differentiation(GO:1903225) |
0.2 | 2.5 | GO:0007042 | lysosomal lumen acidification(GO:0007042) |
0.2 | 2.5 | GO:0019985 | translesion synthesis(GO:0019985) |
0.2 | 3.5 | GO:0001833 | inner cell mass cell proliferation(GO:0001833) |
0.2 | 2.0 | GO:0033314 | mitotic DNA replication checkpoint(GO:0033314) |
0.2 | 0.8 | GO:1902037 | negative regulation of hematopoietic stem cell differentiation(GO:1902037) |
0.2 | 1.9 | GO:0031119 | tRNA pseudouridine synthesis(GO:0031119) |
0.2 | 0.4 | GO:0031554 | regulation of DNA-templated transcription, termination(GO:0031554) |
0.2 | 0.9 | GO:0034196 | acylglycerol transport(GO:0034196) triglyceride transport(GO:0034197) |
0.2 | 0.3 | GO:1903588 | negative regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis(GO:1903588) |
0.2 | 0.9 | GO:0040032 | post-embryonic body morphogenesis(GO:0040032) |
0.2 | 0.5 | GO:0038095 | Fc-epsilon receptor signaling pathway(GO:0038095) |
0.2 | 0.5 | GO:1904760 | myofibroblast differentiation(GO:0036446) regulation of myofibroblast differentiation(GO:1904760) |
0.2 | 0.8 | GO:0031860 | telomeric 3' overhang formation(GO:0031860) |
0.2 | 2.3 | GO:0070935 | 3'-UTR-mediated mRNA stabilization(GO:0070935) |
0.2 | 0.8 | GO:0014886 | transition between slow and fast fiber(GO:0014886) |
0.2 | 3.6 | GO:0032897 | negative regulation of viral transcription(GO:0032897) |
0.2 | 1.6 | GO:1902083 | negative regulation of peptidyl-cysteine S-nitrosylation(GO:1902083) |
0.2 | 1.3 | GO:0032876 | negative regulation of DNA endoreduplication(GO:0032876) modulation by host of viral release from host cell(GO:0044789) positive regulation by host of viral release from host cell(GO:0044791) |
0.2 | 1.5 | GO:0031547 | brain-derived neurotrophic factor receptor signaling pathway(GO:0031547) |
0.2 | 1.4 | GO:0042760 | very long-chain fatty acid catabolic process(GO:0042760) |
0.2 | 3.5 | GO:0014912 | negative regulation of smooth muscle cell migration(GO:0014912) |
0.1 | 2.4 | GO:0036297 | interstrand cross-link repair(GO:0036297) |
0.1 | 0.6 | GO:1902626 | assembly of large subunit precursor of preribosome(GO:1902626) |
0.1 | 1.3 | GO:2000051 | negative regulation of non-canonical Wnt signaling pathway(GO:2000051) |
0.1 | 0.5 | GO:0035269 | protein O-linked mannosylation(GO:0035269) |
0.1 | 2.3 | GO:0040034 | regulation of development, heterochronic(GO:0040034) |
0.1 | 0.6 | GO:2001168 | regulation of histone H2B ubiquitination(GO:2001166) positive regulation of histone H2B ubiquitination(GO:2001168) |
0.1 | 0.5 | GO:0010700 | negative regulation of norepinephrine secretion(GO:0010700) |
0.1 | 0.9 | GO:0032790 | ribosome disassembly(GO:0032790) |
0.1 | 6.3 | GO:0045737 | positive regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0045737) |
0.1 | 5.4 | GO:0070303 | negative regulation of stress-activated MAPK cascade(GO:0032873) negative regulation of stress-activated protein kinase signaling cascade(GO:0070303) |
0.1 | 1.5 | GO:0043982 | histone H4-K5 acetylation(GO:0043981) histone H4-K8 acetylation(GO:0043982) |
0.1 | 8.0 | GO:0006635 | fatty acid beta-oxidation(GO:0006635) |
0.1 | 0.3 | GO:0071921 | establishment of sister chromatid cohesion(GO:0034085) cohesin loading(GO:0071921) regulation of cohesin loading(GO:0071922) |
0.1 | 1.6 | GO:0043162 | ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway(GO:0043162) |
0.1 | 0.7 | GO:0046784 | viral mRNA export from host cell nucleus(GO:0046784) |
0.1 | 0.7 | GO:0042590 | antigen processing and presentation of exogenous peptide antigen via MHC class I(GO:0042590) |
0.1 | 2.7 | GO:0010960 | magnesium ion homeostasis(GO:0010960) |
0.1 | 1.8 | GO:0043968 | histone H2A acetylation(GO:0043968) |
0.1 | 3.3 | GO:0031146 | SCF-dependent proteasomal ubiquitin-dependent protein catabolic process(GO:0031146) |
0.1 | 0.3 | GO:0031590 | wybutosine metabolic process(GO:0031590) wybutosine biosynthetic process(GO:0031591) |
0.1 | 0.5 | GO:0036066 | protein O-linked fucosylation(GO:0036066) |
0.1 | 0.4 | GO:1900095 | regulation of dosage compensation by inactivation of X chromosome(GO:1900095) |
0.1 | 2.6 | GO:0034723 | DNA replication-dependent nucleosome assembly(GO:0006335) DNA replication-dependent nucleosome organization(GO:0034723) |
0.1 | 0.6 | GO:0031665 | negative regulation of lipopolysaccharide-mediated signaling pathway(GO:0031665) |
0.1 | 0.6 | GO:0006451 | selenocysteine incorporation(GO:0001514) translational readthrough(GO:0006451) |
0.1 | 5.5 | GO:0001824 | blastocyst development(GO:0001824) |
0.1 | 0.4 | GO:0006290 | pyrimidine dimer repair(GO:0006290) activation of JNKK activity(GO:0007256) |
0.1 | 1.1 | GO:0014823 | response to activity(GO:0014823) |
0.1 | 1.5 | GO:0006298 | mismatch repair(GO:0006298) |
0.1 | 3.0 | GO:0035411 | catenin import into nucleus(GO:0035411) |
0.1 | 0.3 | GO:0050651 | dermatan sulfate proteoglycan biosynthetic process(GO:0050651) |
0.1 | 0.5 | GO:0019885 | antigen processing and presentation of endogenous peptide antigen via MHC class I(GO:0019885) |
0.1 | 0.8 | GO:0016926 | protein desumoylation(GO:0016926) |
0.1 | 2.4 | GO:0032728 | positive regulation of interferon-beta production(GO:0032728) |
0.1 | 0.2 | GO:1902268 | negative regulation of polyamine transmembrane transport(GO:1902268) |
0.1 | 2.8 | GO:0010501 | RNA secondary structure unwinding(GO:0010501) |
0.1 | 2.0 | GO:0000002 | mitochondrial genome maintenance(GO:0000002) |
0.1 | 0.5 | GO:1902570 | protein localization to nucleolus(GO:1902570) |
0.1 | 3.2 | GO:0035914 | skeletal muscle cell differentiation(GO:0035914) |
0.1 | 0.5 | GO:0002467 | germinal center formation(GO:0002467) |
0.1 | 0.7 | GO:0015937 | coenzyme A biosynthetic process(GO:0015937) |
0.1 | 3.8 | GO:0010923 | negative regulation of phosphatase activity(GO:0010923) |
0.1 | 0.7 | GO:0071044 | histone mRNA catabolic process(GO:0071044) |
0.1 | 0.3 | GO:0052428 | modulation of molecular function in other organism(GO:0044359) negative regulation of molecular function in other organism(GO:0044362) negative regulation of molecular function in other organism involved in symbiotic interaction(GO:0052204) modulation of molecular function in other organism involved in symbiotic interaction(GO:0052205) negative regulation by host of symbiont molecular function(GO:0052405) modification by host of symbiont molecular function(GO:0052428) |
0.0 | 2.0 | GO:0043631 | mRNA polyadenylation(GO:0006378) RNA polyadenylation(GO:0043631) |
0.0 | 0.7 | GO:0090110 | cargo loading into COPII-coated vesicle(GO:0090110) |
0.0 | 0.2 | GO:0070317 | negative regulation of G0 to G1 transition(GO:0070317) |
0.0 | 1.9 | GO:0006506 | GPI anchor biosynthetic process(GO:0006506) |
0.0 | 0.6 | GO:0046855 | phosphorylated carbohydrate dephosphorylation(GO:0046838) inositol phosphate dephosphorylation(GO:0046855) |
0.0 | 0.4 | GO:0097067 | cellular response to thyroid hormone stimulus(GO:0097067) |
0.0 | 0.4 | GO:0006301 | postreplication repair(GO:0006301) |
0.0 | 1.0 | GO:0000079 | regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0000079) |
0.0 | 0.1 | GO:1905034 | regulation of antifungal innate immune response(GO:1905034) negative regulation of antifungal innate immune response(GO:1905035) |
0.0 | 0.4 | GO:0048096 | chromatin-mediated maintenance of transcription(GO:0048096) |
0.0 | 1.1 | GO:0042491 | auditory receptor cell differentiation(GO:0042491) |
0.0 | 0.2 | GO:0008063 | Toll signaling pathway(GO:0008063) |
0.0 | 2.2 | GO:0032414 | positive regulation of ion transmembrane transporter activity(GO:0032414) |
0.0 | 0.1 | GO:1902953 | positive regulation of ER to Golgi vesicle-mediated transport(GO:1902953) |
0.0 | 0.4 | GO:0046827 | positive regulation of protein export from nucleus(GO:0046827) |
0.0 | 0.0 | GO:0000966 | RNA 5'-end processing(GO:0000966) |
0.0 | 0.8 | GO:0006383 | transcription from RNA polymerase III promoter(GO:0006383) |
0.0 | 1.1 | GO:0034394 | protein localization to cell surface(GO:0034394) |
0.0 | 0.2 | GO:0001682 | tRNA 5'-leader removal(GO:0001682) |
0.0 | 0.6 | GO:0070979 | protein K11-linked ubiquitination(GO:0070979) |
0.0 | 0.6 | GO:0030970 | retrograde protein transport, ER to cytosol(GO:0030970) |
0.0 | 1.9 | GO:0008203 | cholesterol metabolic process(GO:0008203) |
0.0 | 0.3 | GO:0060765 | regulation of androgen receptor signaling pathway(GO:0060765) |
0.0 | 0.4 | GO:0048025 | negative regulation of mRNA splicing, via spliceosome(GO:0048025) |
0.0 | 1.3 | GO:0032436 | positive regulation of proteasomal ubiquitin-dependent protein catabolic process(GO:0032436) |
0.0 | 1.3 | GO:0007631 | feeding behavior(GO:0007631) |
0.0 | 3.1 | GO:0016485 | protein processing(GO:0016485) |
0.0 | 0.2 | GO:0051044 | positive regulation of membrane protein ectodomain proteolysis(GO:0051044) |
0.0 | 1.7 | GO:0043524 | negative regulation of neuron apoptotic process(GO:0043524) |
0.0 | 0.1 | GO:0042407 | cristae formation(GO:0042407) |
0.0 | 0.8 | GO:0007338 | single fertilization(GO:0007338) |
Gene overrepresentation in cellular_component category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
2.6 | 7.7 | GO:0036125 | mitochondrial fatty acid beta-oxidation multienzyme complex(GO:0016507) fatty acid beta-oxidation multienzyme complex(GO:0036125) |
1.6 | 16.3 | GO:0000796 | condensin complex(GO:0000796) |
1.3 | 5.0 | GO:0000942 | condensed nuclear chromosome outer kinetochore(GO:0000942) |
1.0 | 4.8 | GO:0036449 | microtubule minus-end(GO:0036449) |
0.9 | 3.7 | GO:0090537 | CERF complex(GO:0090537) |
0.9 | 3.7 | GO:0070552 | BRISC complex(GO:0070552) |
0.8 | 3.4 | GO:0000939 | nuclear MIS12/MIND complex(GO:0000818) condensed chromosome inner kinetochore(GO:0000939) |
0.7 | 2.6 | GO:1990452 | Parkin-FBXW7-Cul1 ubiquitin ligase complex(GO:1990452) |
0.5 | 3.8 | GO:0036195 | muscle cell projection(GO:0036194) muscle cell projection membrane(GO:0036195) |
0.5 | 2.9 | GO:1990356 | sumoylated E2 ligase complex(GO:1990356) |
0.4 | 1.2 | GO:0097543 | ciliary inversin compartment(GO:0097543) |
0.4 | 3.1 | GO:0033269 | internode region of axon(GO:0033269) |
0.4 | 2.5 | GO:0031465 | Cul4B-RING E3 ubiquitin ligase complex(GO:0031465) |
0.3 | 1.3 | GO:0034991 | nuclear meiotic cohesin complex(GO:0034991) |
0.3 | 1.1 | GO:0045251 | mitochondrial electron transfer flavoprotein complex(GO:0017133) electron transfer flavoprotein complex(GO:0045251) |
0.2 | 0.7 | GO:0005588 | collagen type V trimer(GO:0005588) |
0.2 | 3.0 | GO:0000506 | glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex(GO:0000506) |
0.2 | 2.6 | GO:0031011 | Ino80 complex(GO:0031011) |
0.2 | 9.0 | GO:0000307 | cyclin-dependent protein kinase holoenzyme complex(GO:0000307) |
0.2 | 3.2 | GO:0016580 | Sin3 complex(GO:0016580) |
0.1 | 0.6 | GO:0000931 | gamma-tubulin large complex(GO:0000931) gamma-tubulin ring complex(GO:0008274) |
0.1 | 0.8 | GO:0030870 | Mre11 complex(GO:0030870) |
0.1 | 0.8 | GO:0032299 | ribonuclease H2 complex(GO:0032299) |
0.1 | 1.7 | GO:0005862 | muscle thin filament tropomyosin(GO:0005862) |
0.1 | 2.9 | GO:0005942 | phosphatidylinositol 3-kinase complex(GO:0005942) |
0.1 | 0.6 | GO:0000839 | Hrd1p ubiquitin ligase ERAD-L complex(GO:0000839) |
0.1 | 0.9 | GO:0042382 | paraspeckles(GO:0042382) |
0.1 | 2.4 | GO:0005666 | DNA-directed RNA polymerase III complex(GO:0005666) |
0.1 | 1.0 | GO:0090543 | Flemming body(GO:0090543) |
0.1 | 0.8 | GO:0097413 | Lewy body(GO:0097413) |
0.1 | 0.8 | GO:0000127 | transcription factor TFIIIC complex(GO:0000127) |
0.1 | 0.6 | GO:0090571 | RNA polymerase II transcription repressor complex(GO:0090571) |
0.1 | 1.4 | GO:0031233 | intrinsic component of external side of plasma membrane(GO:0031233) |
0.1 | 1.4 | GO:0005662 | DNA replication factor A complex(GO:0005662) |
0.1 | 0.6 | GO:0033503 | HULC complex(GO:0033503) |
0.1 | 2.2 | GO:0005680 | anaphase-promoting complex(GO:0005680) |
0.1 | 1.1 | GO:0097542 | ciliary tip(GO:0097542) |
0.1 | 7.2 | GO:0005643 | nuclear pore(GO:0005643) |
0.1 | 2.4 | GO:0035861 | site of double-strand break(GO:0035861) |
0.1 | 3.7 | GO:0016235 | aggresome(GO:0016235) |
0.1 | 1.4 | GO:0031616 | spindle pole centrosome(GO:0031616) |
0.1 | 0.7 | GO:0000347 | THO complex(GO:0000347) THO complex part of transcription export complex(GO:0000445) |
0.1 | 0.5 | GO:0033256 | I-kappaB/NF-kappaB complex(GO:0033256) |
0.1 | 0.4 | GO:0016589 | NURF complex(GO:0016589) |
0.1 | 3.4 | GO:0005871 | kinesin complex(GO:0005871) |
0.1 | 0.3 | GO:0005686 | U2 snRNP(GO:0005686) |
0.1 | 3.0 | GO:0000315 | organellar large ribosomal subunit(GO:0000315) mitochondrial large ribosomal subunit(GO:0005762) |
0.1 | 1.3 | GO:0030992 | intraciliary transport particle B(GO:0030992) |
0.1 | 3.2 | GO:0000794 | condensed nuclear chromosome(GO:0000794) |
0.1 | 0.9 | GO:0031528 | microvillus membrane(GO:0031528) |
0.1 | 1.6 | GO:0000788 | nuclear nucleosome(GO:0000788) |
0.1 | 1.5 | GO:0071339 | MLL1/2 complex(GO:0044665) MLL1 complex(GO:0071339) |
0.0 | 0.9 | GO:0016581 | NuRD complex(GO:0016581) CHD-type complex(GO:0090545) nuclear transcriptional repressor complex(GO:0090568) |
0.0 | 2.1 | GO:0005788 | endoplasmic reticulum lumen(GO:0005788) |
0.0 | 4.5 | GO:0044291 | cell-cell contact zone(GO:0044291) |
0.0 | 2.2 | GO:0097610 | cleavage furrow(GO:0032154) cell surface furrow(GO:0097610) |
0.0 | 3.0 | GO:0005844 | polysome(GO:0005844) |
0.0 | 0.2 | GO:0034715 | U7 snRNP(GO:0005683) pICln-Sm protein complex(GO:0034715) |
0.0 | 0.2 | GO:0005655 | nucleolar ribonuclease P complex(GO:0005655) |
0.0 | 0.2 | GO:0033061 | DNA recombinase mediator complex(GO:0033061) |
0.0 | 1.2 | GO:0042645 | nucleoid(GO:0009295) mitochondrial nucleoid(GO:0042645) |
0.0 | 0.1 | GO:0044530 | supraspliceosomal complex(GO:0044530) |
0.0 | 0.8 | GO:0008023 | transcription elongation factor complex(GO:0008023) |
0.0 | 0.1 | GO:0071920 | cleavage body(GO:0071920) |
0.0 | 1.7 | GO:0000932 | cytoplasmic mRNA processing body(GO:0000932) |
0.0 | 0.1 | GO:0008622 | epsilon DNA polymerase complex(GO:0008622) |
0.0 | 3.3 | GO:0031965 | nuclear membrane(GO:0031965) |
0.0 | 1.0 | GO:0017053 | transcriptional repressor complex(GO:0017053) |
0.0 | 0.2 | GO:0035631 | CD40 receptor complex(GO:0035631) |
0.0 | 0.1 | GO:0061617 | MICOS complex(GO:0061617) |
0.0 | 1.4 | GO:0000781 | chromosome, telomeric region(GO:0000781) |
0.0 | 1.0 | GO:0005901 | caveola(GO:0005901) |
0.0 | 2.3 | GO:0030426 | growth cone(GO:0030426) |
0.0 | 0.1 | GO:0031595 | nuclear proteasome complex(GO:0031595) |
0.0 | 0.3 | GO:0030687 | preribosome, large subunit precursor(GO:0030687) |
0.0 | 0.7 | GO:0019005 | SCF ubiquitin ligase complex(GO:0019005) |
0.0 | 0.3 | GO:0005801 | cis-Golgi network(GO:0005801) |
Gene overrepresentation in molecular_function category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
2.1 | 8.4 | GO:0061575 | cyclin-dependent protein serine/threonine kinase activator activity(GO:0061575) |
1.9 | 7.8 | GO:0016508 | long-chain-enoyl-CoA hydratase activity(GO:0016508) |
1.4 | 4.3 | GO:0044715 | 8-oxo-dGDP phosphatase activity(GO:0044715) |
1.1 | 10.3 | GO:0038062 | protein tyrosine kinase collagen receptor activity(GO:0038062) |
0.9 | 3.4 | GO:0008802 | betaine-aldehyde dehydrogenase activity(GO:0008802) |
0.8 | 5.0 | GO:0010997 | anaphase-promoting complex binding(GO:0010997) |
0.8 | 3.1 | GO:0015410 | manganese-transporting ATPase activity(GO:0015410) |
0.6 | 2.2 | GO:0051378 | serotonin binding(GO:0051378) |
0.5 | 2.2 | GO:0004111 | creatine kinase activity(GO:0004111) |
0.5 | 1.6 | GO:0016494 | C-X-C chemokine receptor activity(GO:0016494) |
0.5 | 4.4 | GO:0005007 | fibroblast growth factor-activated receptor activity(GO:0005007) |
0.5 | 2.9 | GO:0061656 | SUMO conjugating enzyme activity(GO:0061656) |
0.5 | 1.4 | GO:0017099 | very-long-chain-acyl-CoA dehydrogenase activity(GO:0017099) |
0.4 | 2.3 | GO:0001069 | regulatory region RNA binding(GO:0001069) |
0.4 | 1.2 | GO:0016501 | prostacyclin receptor activity(GO:0016501) |
0.4 | 3.0 | GO:0046790 | virion binding(GO:0046790) |
0.4 | 3.2 | GO:0031730 | CCR5 chemokine receptor binding(GO:0031730) |
0.3 | 2.7 | GO:0009019 | tRNA (guanine-N1-)-methyltransferase activity(GO:0009019) |
0.3 | 1.0 | GO:0098809 | nitrite reductase activity(GO:0098809) |
0.3 | 1.3 | GO:0036033 | mediator complex binding(GO:0036033) |
0.3 | 0.6 | GO:0016314 | phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase activity(GO:0016314) |
0.3 | 9.5 | GO:0008139 | nuclear localization sequence binding(GO:0008139) |
0.3 | 0.9 | GO:0004140 | dephospho-CoA kinase activity(GO:0004140) |
0.3 | 2.9 | GO:0035005 | 1-phosphatidylinositol-4-phosphate 3-kinase activity(GO:0035005) |
0.3 | 0.8 | GO:0070139 | ubiquitin-like protein-specific endopeptidase activity(GO:0070137) SUMO-specific endopeptidase activity(GO:0070139) |
0.3 | 16.7 | GO:0001102 | RNA polymerase II activating transcription factor binding(GO:0001102) |
0.3 | 3.0 | GO:0017176 | phosphatidylinositol N-acetylglucosaminyltransferase activity(GO:0017176) |
0.2 | 0.6 | GO:0034211 | GTP-dependent protein kinase activity(GO:0034211) |
0.2 | 1.9 | GO:0097200 | cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:0097200) |
0.2 | 2.1 | GO:0003689 | DNA clamp loader activity(GO:0003689) protein-DNA loading ATPase activity(GO:0033170) |
0.2 | 0.4 | GO:0001160 | transcription termination site sequence-specific DNA binding(GO:0001147) transcription termination site DNA binding(GO:0001160) |
0.2 | 2.9 | GO:0030957 | Tat protein binding(GO:0030957) |
0.2 | 2.0 | GO:0008525 | phosphatidylcholine transporter activity(GO:0008525) |
0.2 | 3.5 | GO:0030215 | semaphorin receptor binding(GO:0030215) |
0.2 | 0.5 | GO:0004534 | 5'-3' exoribonuclease activity(GO:0004534) |
0.2 | 1.5 | GO:0043995 | histone acetyltransferase activity (H4-K5 specific)(GO:0043995) histone acetyltransferase activity (H4-K8 specific)(GO:0043996) histone acetyltransferase activity (H4-K16 specific)(GO:0046972) |
0.2 | 0.5 | GO:0031686 | A1 adenosine receptor binding(GO:0031686) |
0.2 | 1.6 | GO:0051575 | 5'-deoxyribose-5-phosphate lyase activity(GO:0051575) |
0.1 | 1.0 | GO:0098821 | BMP receptor activity(GO:0098821) |
0.1 | 2.4 | GO:0097371 | MDM2/MDM4 family protein binding(GO:0097371) |
0.1 | 2.4 | GO:0001056 | RNA polymerase III activity(GO:0001056) |
0.1 | 13.3 | GO:0003697 | single-stranded DNA binding(GO:0003697) |
0.1 | 1.9 | GO:0009982 | pseudouridine synthase activity(GO:0009982) |
0.1 | 0.4 | GO:0000403 | Y-form DNA binding(GO:0000403) |
0.1 | 3.2 | GO:0043425 | bHLH transcription factor binding(GO:0043425) |
0.1 | 7.6 | GO:0004252 | serine-type endopeptidase activity(GO:0004252) |
0.1 | 2.0 | GO:0008266 | poly(U) RNA binding(GO:0008266) |
0.1 | 1.1 | GO:0002161 | aminoacyl-tRNA editing activity(GO:0002161) |
0.1 | 3.5 | GO:0004407 | histone deacetylase activity(GO:0004407) |
0.1 | 0.7 | GO:1990825 | sequence-specific mRNA binding(GO:1990825) |
0.1 | 0.9 | GO:0047391 | alkylglycerophosphoethanolamine phosphodiesterase activity(GO:0047391) |
0.1 | 0.5 | GO:0034056 | estrogen response element binding(GO:0034056) |
0.1 | 3.6 | GO:0061631 | ubiquitin conjugating enzyme activity(GO:0061631) ubiquitin-like protein conjugating enzyme activity(GO:0061650) |
0.1 | 2.2 | GO:0008236 | serine-type peptidase activity(GO:0008236) |
0.1 | 0.3 | GO:0072542 | protein phosphatase activator activity(GO:0072542) |
0.1 | 0.3 | GO:0003880 | protein C-terminal carboxyl O-methyltransferase activity(GO:0003880) |
0.1 | 2.6 | GO:0031492 | nucleosomal DNA binding(GO:0031492) |
0.1 | 0.5 | GO:0008417 | fucosyltransferase activity(GO:0008417) |
0.1 | 3.1 | GO:0032266 | phosphatidylinositol-3-phosphate binding(GO:0032266) |
0.1 | 0.9 | GO:0055106 | ubiquitin-protein transferase regulator activity(GO:0055106) |
0.1 | 0.5 | GO:0005138 | interleukin-6 receptor binding(GO:0005138) |
0.1 | 0.6 | GO:0008379 | thioredoxin peroxidase activity(GO:0008379) |
0.1 | 3.3 | GO:0031593 | polyubiquitin binding(GO:0031593) |
0.1 | 1.1 | GO:0004435 | phosphatidylinositol phospholipase C activity(GO:0004435) |
0.1 | 1.1 | GO:0008510 | sodium:bicarbonate symporter activity(GO:0008510) |
0.1 | 0.2 | GO:0008073 | ornithine decarboxylase inhibitor activity(GO:0008073) |
0.1 | 5.6 | GO:0008083 | growth factor activity(GO:0008083) |
0.1 | 2.1 | GO:0005109 | frizzled binding(GO:0005109) |
0.1 | 1.4 | GO:0043236 | laminin binding(GO:0043236) |
0.0 | 12.6 | GO:0061630 | ubiquitin protein ligase activity(GO:0061630) |
0.0 | 0.6 | GO:0048407 | platelet-derived growth factor binding(GO:0048407) |
0.0 | 14.2 | GO:0001077 | transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001077) |
0.0 | 0.5 | GO:0045295 | gamma-catenin binding(GO:0045295) |
0.0 | 0.4 | GO:0016861 | intramolecular oxidoreductase activity, interconverting aldoses and ketoses(GO:0016861) |
0.0 | 3.4 | GO:0003777 | microtubule motor activity(GO:0003777) |
0.0 | 3.8 | GO:0008026 | ATP-dependent helicase activity(GO:0008026) purine NTP-dependent helicase activity(GO:0070035) |
0.0 | 0.9 | GO:0034185 | apolipoprotein binding(GO:0034185) |
0.0 | 0.6 | GO:0070063 | RNA polymerase binding(GO:0070063) |
0.0 | 0.7 | GO:0001106 | RNA polymerase II transcription corepressor activity(GO:0001106) |
0.0 | 1.1 | GO:0008307 | structural constituent of muscle(GO:0008307) |
0.0 | 0.2 | GO:0051185 | coenzyme transporter activity(GO:0051185) |
0.0 | 0.4 | GO:0030296 | protein tyrosine kinase activator activity(GO:0030296) |
0.0 | 5.9 | GO:0001227 | transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001227) |
0.0 | 0.8 | GO:0051019 | mitogen-activated protein kinase binding(GO:0051019) |
0.0 | 12.9 | GO:0004674 | protein serine/threonine kinase activity(GO:0004674) |
0.0 | 0.3 | GO:0008649 | rRNA methyltransferase activity(GO:0008649) |
0.0 | 0.2 | GO:0031996 | thioesterase binding(GO:0031996) |
0.0 | 0.9 | GO:0043130 | ubiquitin binding(GO:0043130) |
0.0 | 2.2 | GO:0001228 | transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001228) |
0.0 | 0.3 | GO:0019213 | deacetylase activity(GO:0019213) |
0.0 | 0.2 | GO:0004526 | ribonuclease P activity(GO:0004526) |
0.0 | 3.8 | GO:0004842 | ubiquitin-protein transferase activity(GO:0004842) |
0.0 | 1.5 | GO:0004860 | protein kinase inhibitor activity(GO:0004860) |
0.0 | 1.1 | GO:0050660 | flavin adenine dinucleotide binding(GO:0050660) |
0.0 | 1.5 | GO:0004725 | protein tyrosine phosphatase activity(GO:0004725) |
0.0 | 2.2 | GO:0042393 | histone binding(GO:0042393) |
0.0 | 0.2 | GO:0031491 | nucleosome binding(GO:0031491) |
0.0 | 1.7 | GO:0017137 | Rab GTPase binding(GO:0017137) |
0.0 | 0.1 | GO:0036402 | proteasome-activating ATPase activity(GO:0036402) |
0.0 | 0.1 | GO:0050733 | RS domain binding(GO:0050733) |
0.0 | 1.1 | GO:0042626 | ATPase activity, coupled to transmembrane movement of substances(GO:0042626) |
Gene overrepresentation in C2:CP category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.3 | 16.8 | PID_IL12_2PATHWAY | IL12-mediated signaling events |
0.3 | 8.1 | PID_SMAD2_3PATHWAY | Regulation of cytoplasmic and nuclear SMAD2/3 signaling |
0.2 | 10.4 | PID_AURORA_B_PATHWAY | Aurora B signaling |
0.2 | 7.2 | PID_SYNDECAN_4_PATHWAY | Syndecan-4-mediated signaling events |
0.2 | 9.0 | PID_FOXM1_PATHWAY | FOXM1 transcription factor network |
0.2 | 1.5 | ST_TYPE_I_INTERFERON_PATHWAY | Type I Interferon (alpha/beta IFN) Pathway |
0.2 | 6.6 | PID_AURORA_A_PATHWAY | Aurora A signaling |
0.2 | 4.7 | PID_BETA_CATENIN_DEG_PATHWAY | Degradation of beta catenin |
0.1 | 1.4 | PID_THROMBIN_PAR4_PATHWAY | PAR4-mediated thrombin signaling events |
0.1 | 3.8 | PID_PS1_PATHWAY | Presenilin action in Notch and Wnt signaling |
0.1 | 4.4 | PID_HNF3A_PATHWAY | FOXA1 transcription factor network |
0.1 | 3.9 | PID_ATM_PATHWAY | ATM pathway |
0.1 | 1.9 | PID_CD40_PATHWAY | CD40/CD40L signaling |
0.1 | 1.6 | PID_DNA_PK_PATHWAY | DNA-PK pathway in nonhomologous end joining |
0.1 | 1.5 | PID_MYC_PATHWAY | C-MYC pathway |
0.1 | 3.0 | PID_P53_REGULATION_PATHWAY | p53 pathway |
0.1 | 2.0 | PID_FANCONI_PATHWAY | Fanconi anemia pathway |
0.1 | 1.5 | PID_HIV_NEF_PATHWAY | HIV-1 Nef: Negative effector of Fas and TNF-alpha |
0.0 | 3.7 | SIG_INSULIN_RECEPTOR_PATHWAY_IN_CARDIAC_MYOCYTES | Genes related to the insulin receptor pathway |
0.0 | 1.4 | PID_HNF3B_PATHWAY | FOXA2 and FOXA3 transcription factor networks |
0.0 | 3.2 | PID_SMAD2_3NUCLEAR_PATHWAY | Regulation of nuclear SMAD2/3 signaling |
0.0 | 1.6 | PID_RB_1PATHWAY | Regulation of retinoblastoma protein |
0.0 | 1.8 | PID_AVB3_INTEGRIN_PATHWAY | Integrins in angiogenesis |
0.0 | 0.5 | PID_NCADHERIN_PATHWAY | N-cadherin signaling events |
0.0 | 0.6 | PID_ARF6_TRAFFICKING_PATHWAY | Arf6 trafficking events |
0.0 | 1.6 | NABA_ECM_AFFILIATED | Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins |
Gene overrepresentation in C2:CP:REACTOME category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.5 | 9.1 | REACTOME_MITOCHONDRIAL_FATTY_ACID_BETA_OXIDATION | Genes involved in Mitochondrial Fatty Acid Beta-Oxidation |
0.4 | 1.6 | REACTOME_CDC6_ASSOCIATION_WITH_THE_ORC_ORIGIN_COMPLEX | Genes involved in CDC6 association with the ORC:origin complex |
0.3 | 5.0 | REACTOME_CYCLIN_A_B1_ASSOCIATED_EVENTS_DURING_G2_M_TRANSITION | Genes involved in Cyclin A/B1 associated events during G2/M transition |
0.3 | 10.6 | REACTOME_ACTIVATION_OF_ATR_IN_RESPONSE_TO_REPLICATION_STRESS | Genes involved in Activation of ATR in response to replication stress |
0.3 | 4.8 | REACTOME_DESTABILIZATION_OF_MRNA_BY_TRISTETRAPROLIN_TTP | Genes involved in Destabilization of mRNA by Tristetraprolin (TTP) |
0.2 | 6.7 | REACTOME_SYNTHESIS_OF_GLYCOSYLPHOSPHATIDYLINOSITOL_GPI | Genes involved in Synthesis of glycosylphosphatidylinositol (GPI) |
0.2 | 2.6 | REACTOME_PROLACTIN_RECEPTOR_SIGNALING | Genes involved in Prolactin receptor signaling |
0.2 | 2.9 | REACTOME_RECEPTOR_LIGAND_BINDING_INITIATES_THE_SECOND_PROTEOLYTIC_CLEAVAGE_OF_NOTCH_RECEPTOR | Genes involved in Receptor-ligand binding initiates the second proteolytic cleavage of Notch receptor |
0.2 | 2.9 | REACTOME_SYNTHESIS_OF_PIPS_AT_THE_EARLY_ENDOSOME_MEMBRANE | Genes involved in Synthesis of PIPs at the early endosome membrane |
0.2 | 4.0 | REACTOME_APC_CDC20_MEDIATED_DEGRADATION_OF_NEK2A | Genes involved in APC-Cdc20 mediated degradation of Nek2A |
0.1 | 3.0 | REACTOME_TGF_BETA_RECEPTOR_SIGNALING_IN_EMT_EPITHELIAL_TO_MESENCHYMAL_TRANSITION | Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition) |
0.1 | 3.6 | REACTOME_SIGNALING_BY_HIPPO | Genes involved in Signaling by Hippo |
0.1 | 2.2 | REACTOME_LIGAND_GATED_ION_CHANNEL_TRANSPORT | Genes involved in Ligand-gated ion channel transport |
0.1 | 2.4 | REACTOME_RNA_POL_III_CHAIN_ELONGATION | Genes involved in RNA Polymerase III Chain Elongation |
0.1 | 2.0 | REACTOME_FANCONI_ANEMIA_PATHWAY | Genes involved in Fanconi Anemia pathway |
0.1 | 2.1 | REACTOME_CASPASE_MEDIATED_CLEAVAGE_OF_CYTOSKELETAL_PROTEINS | Genes involved in Caspase-mediated cleavage of cytoskeletal proteins |
0.1 | 0.8 | REACTOME_HOMOLOGOUS_RECOMBINATION_REPAIR_OF_REPLICATION_INDEPENDENT_DOUBLE_STRAND_BREAKS | Genes involved in Homologous recombination repair of replication-independent double-strand breaks |
0.1 | 1.6 | REACTOME_EARLY_PHASE_OF_HIV_LIFE_CYCLE | Genes involved in Early Phase of HIV Life Cycle |
0.1 | 5.8 | REACTOME_MEIOTIC_SYNAPSIS | Genes involved in Meiotic Synapsis |
0.1 | 6.0 | REACTOME_ANTIVIRAL_MECHANISM_BY_IFN_STIMULATED_GENES | Genes involved in Antiviral mechanism by IFN-stimulated genes |
0.1 | 1.7 | REACTOME_STRIATED_MUSCLE_CONTRACTION | Genes involved in Striated Muscle Contraction |
0.1 | 1.2 | REACTOME_ANTIGEN_PRESENTATION_FOLDING_ASSEMBLY_AND_PEPTIDE_LOADING_OF_CLASS_I_MHC | Genes involved in Antigen Presentation: Folding, assembly and peptide loading of class I MHC |
0.1 | 1.9 | REACTOME_SIGNALING_BY_FGFR1_FUSION_MUTANTS | Genes involved in Signaling by FGFR1 fusion mutants |
0.1 | 0.9 | REACTOME_CHYLOMICRON_MEDIATED_LIPID_TRANSPORT | Genes involved in Chylomicron-mediated lipid transport |
0.1 | 0.5 | REACTOME_P2Y_RECEPTORS | Genes involved in P2Y receptors |
0.1 | 0.7 | REACTOME_VITAMIN_B5_PANTOTHENATE_METABOLISM | Genes involved in Vitamin B5 (pantothenate) metabolism |
0.0 | 1.7 | REACTOME_ION_TRANSPORT_BY_P_TYPE_ATPASES | Genes involved in Ion transport by P-type ATPases |
0.0 | 1.4 | REACTOME_SEMA4D_INDUCED_CELL_MIGRATION_AND_GROWTH_CONE_COLLAPSE | Genes involved in Sema4D induced cell migration and growth-cone collapse |
0.0 | 1.0 | REACTOME_SULFUR_AMINO_ACID_METABOLISM | Genes involved in Sulfur amino acid metabolism |
0.0 | 6.0 | REACTOME_METABOLISM_OF_AMINO_ACIDS_AND_DERIVATIVES | Genes involved in Metabolism of amino acids and derivatives |
0.0 | 0.8 | REACTOME_METABOLISM_OF_NON_CODING_RNA | Genes involved in Metabolism of non-coding RNA |
0.0 | 2.3 | REACTOME_MITOTIC_PROMETAPHASE | Genes involved in Mitotic Prometaphase |
0.0 | 0.5 | REACTOME_SIGNALING_BY_SCF_KIT | Genes involved in Signaling by SCF-KIT |
0.0 | 0.9 | REACTOME_PROSTACYCLIN_SIGNALLING_THROUGH_PROSTACYCLIN_RECEPTOR | Genes involved in Prostacyclin signalling through prostacyclin receptor |
0.0 | 0.5 | REACTOME_RIP_MEDIATED_NFKB_ACTIVATION_VIA_DAI | Genes involved in RIP-mediated NFkB activation via DAI |
0.0 | 0.2 | REACTOME_ACTIVATION_OF_IRF3_IRF7_MEDIATED_BY_TBK1_IKK_EPSILON | Genes involved in Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon |
0.0 | 1.2 | REACTOME_NUCLEAR_RECEPTOR_TRANSCRIPTION_PATHWAY | Genes involved in Nuclear Receptor transcription pathway |
0.0 | 0.4 | REACTOME_RNA_POL_I_TRANSCRIPTION_INITIATION | Genes involved in RNA Polymerase I Transcription Initiation |
0.0 | 0.7 | REACTOME_NCAM1_INTERACTIONS | Genes involved in NCAM1 interactions |
0.0 | 0.7 | REACTOME_CIRCADIAN_CLOCK | Genes involved in Circadian Clock |
0.0 | 0.3 | REACTOME_A_TETRASACCHARIDE_LINKER_SEQUENCE_IS_REQUIRED_FOR_GAG_SYNTHESIS | Genes involved in A tetrasaccharide linker sequence is required for GAG synthesis |
0.0 | 1.8 | REACTOME_ANTIGEN_PROCESSING_UBIQUITINATION_PROTEASOME_DEGRADATION | Genes involved in Antigen processing: Ubiquitination & Proteasome degradation |