Motif ID: Hinfp

Z-value: 1.386


Transcription factors associated with Hinfp:

Gene SymbolEntrez IDGene Name
Hinfp ENSMUSG00000032119.4 Hinfp

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Hinfpmm10_v2_chr9_-_44305595_44305688-0.096.1e-01Click!


Activity profile for motif Hinfp.

activity profile for motif Hinfp


Sorted Z-values histogram for motif Hinfp

Sorted Z-values for motif Hinfp



Network of associatons between targets according to the STRING database.



First level regulatory network of Hinfp

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr5_-_106458440 8.974 ENSMUST00000086795.6
 Barhl2
BarH-like 2 (Drosophila)
chr11_+_80300866 8.677 ENSMUST00000017836.7
 Rhbdl3
rhomboid, veinlet-like 3 (Drosophila)
chr13_+_51645232 8.386 ENSMUST00000075853.5
 Cks2
CDC28 protein kinase regulatory subunit 2
chr9_+_118478182 8.284 ENSMUST00000111763.1
 Eomes
eomesodermin homolog (Xenopus laevis)
chr9_+_118478344 8.010 ENSMUST00000035020.8
 Eomes
eomesodermin homolog (Xenopus laevis)
chr17_-_35702297 5.767 ENSMUST00000135078.1
 Ddr1
discoidin domain receptor family, member 1
chr2_-_91931675 5.621 ENSMUST00000111309.1
 Mdk
midkine
chr19_+_25610533 5.611 ENSMUST00000048935.4
 Dmrt3
doublesex and mab-3 related transcription factor 3
chr14_+_65806066 5.407 ENSMUST00000139644.1
 Pbk
PDZ binding kinase
chr7_+_122159422 5.026 ENSMUST00000033154.6
 Plk1
polo-like kinase 1
chr4_+_52439235 4.901 ENSMUST00000117280.1
ENSMUST00000102915.3
ENSMUST00000142227.1
 Smc2


structural maintenance of chromosomes 2


chr1_+_139454747 4.792 ENSMUST00000053364.8
ENSMUST00000097554.3
 Aspm

asp (abnormal spindle)-like, microcephaly associated (Drosophila)

chr5_+_33658123 4.597 ENSMUST00000074849.6
ENSMUST00000079534.4
 Tacc3

transforming, acidic coiled-coil containing protein 3

chr17_-_35701937 4.518 ENSMUST00000155628.1
 Ddr1
discoidin domain receptor family, member 1
chr4_+_97777606 4.387 ENSMUST00000075448.6
ENSMUST00000092532.6
 Nfia

nuclear factor I/A

chr3_+_69004711 4.385 ENSMUST00000042901.8
 Smc4
structural maintenance of chromosomes 4
chr14_-_8666236 4.383 ENSMUST00000102996.3
 4930452B06Rik
RIKEN cDNA 4930452B06 gene
chr5_+_108694222 4.352 ENSMUST00000013633.8
ENSMUST00000112560.3
 Fgfrl1

fibroblast growth factor receptor-like 1

chr1_+_191821444 3.972 ENSMUST00000027931.7
 Nek2
NIMA (never in mitosis gene a)-related expressed kinase 2
chr2_+_84840612 3.908 ENSMUST00000111625.1
 Slc43a1
solute carrier family 43, member 1

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 150 entries
Log-likelihood per target Total log-likelihoodTermDescription
5.4 16.3 GO:0002302 CD8-positive, alpha-beta T cell differentiation involved in immune response(GO:0002302)
1.6 13.1 GO:0010032 meiotic chromosome condensation(GO:0010032)
0.9 10.3 GO:0061302 smooth muscle cell-matrix adhesion(GO:0061302)
0.2 9.0 GO:0001709 cell fate determination(GO:0001709)
0.1 8.0 GO:0006635 fatty acid beta-oxidation(GO:0006635)
0.4 7.6 GO:0030953 astral microtubule organization(GO:0030953)
1.4 7.1 GO:0007089 traversing start control point of mitotic cell cycle(GO:0007089)
0.1 6.3 GO:0045737 positive regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0045737)
0.4 5.9 GO:0043249 erythrocyte maturation(GO:0043249)
1.9 5.6 GO:0030421 defecation(GO:0030421)
0.5 5.6 GO:0042487 regulation of odontogenesis of dentin-containing tooth(GO:0042487)
0.1 5.5 GO:0001824 blastocyst development(GO:0001824)
0.1 5.4 GO:0070303 negative regulation of stress-activated MAPK cascade(GO:0032873) negative regulation of stress-activated protein kinase signaling cascade(GO:0070303)
1.3 5.0 GO:0040038 polar body extrusion after meiotic divisions(GO:0040038)
1.0 4.8 GO:0051661 maintenance of centrosome location(GO:0051661)
1.2 4.7 GO:0006014 D-ribose metabolic process(GO:0006014)
0.3 4.6 GO:0006607 NLS-bearing protein import into nucleus(GO:0006607)
0.4 4.4 GO:0060539 diaphragm development(GO:0060539)
0.3 4.4 GO:0072189 ureter development(GO:0072189)
0.4 4.3 GO:0006610 ribosomal protein import into nucleus(GO:0006610)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 77 entries
Log-likelihood per target Total log-likelihoodTermDescription
1.6 16.3 GO:0000796 condensin complex(GO:0000796)
0.2 9.0 GO:0000307 cyclin-dependent protein kinase holoenzyme complex(GO:0000307)
2.6 7.7 GO:0036125 mitochondrial fatty acid beta-oxidation multienzyme complex(GO:0016507) fatty acid beta-oxidation multienzyme complex(GO:0036125)
0.1 7.2 GO:0005643 nuclear pore(GO:0005643)
1.3 5.0 GO:0000942 condensed nuclear chromosome outer kinetochore(GO:0000942)
1.0 4.8 GO:0036449 microtubule minus-end(GO:0036449)
0.0 4.5 GO:0044291 cell-cell contact zone(GO:0044291)
0.5 3.8 GO:0036195 muscle cell projection(GO:0036194) muscle cell projection membrane(GO:0036195)
0.9 3.7 GO:0090537 CERF complex(GO:0090537)
0.9 3.7 GO:0070552 BRISC complex(GO:0070552)
0.1 3.7 GO:0016235 aggresome(GO:0016235)
0.8 3.4 GO:0000939 nuclear MIS12/MIND complex(GO:0000818) condensed chromosome inner kinetochore(GO:0000939)
0.1 3.4 GO:0005871 kinesin complex(GO:0005871)
0.0 3.3 GO:0031965 nuclear membrane(GO:0031965)
0.2 3.2 GO:0016580 Sin3 complex(GO:0016580)
0.1 3.2 GO:0000794 condensed nuclear chromosome(GO:0000794)
0.4 3.1 GO:0033269 internode region of axon(GO:0033269)
0.2 3.0 GO:0000506 glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex(GO:0000506)
0.1 3.0 GO:0000315 organellar large ribosomal subunit(GO:0000315) mitochondrial large ribosomal subunit(GO:0005762)
0.0 3.0 GO:0005844 polysome(GO:0005844)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 101 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.3 16.7 GO:0001102 RNA polymerase II activating transcription factor binding(GO:0001102)
0.0 14.2 GO:0001077 transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001077)
0.1 13.3 GO:0003697 single-stranded DNA binding(GO:0003697)
0.0 12.9 GO:0004674 protein serine/threonine kinase activity(GO:0004674)
0.0 12.6 GO:0061630 ubiquitin protein ligase activity(GO:0061630)
1.1 10.3 GO:0038062 protein tyrosine kinase collagen receptor activity(GO:0038062)
0.3 9.5 GO:0008139 nuclear localization sequence binding(GO:0008139)
2.1 8.4 GO:0061575 cyclin-dependent protein serine/threonine kinase activator activity(GO:0061575)
1.9 7.8 GO:0016508 long-chain-enoyl-CoA hydratase activity(GO:0016508)
0.1 7.6 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.0 5.9 GO:0001227 transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001227)
0.1 5.6 GO:0008083 growth factor activity(GO:0008083)
0.8 5.0 GO:0010997 anaphase-promoting complex binding(GO:0010997)
0.5 4.4 GO:0005007 fibroblast growth factor-activated receptor activity(GO:0005007)
1.4 4.3 GO:0044715 8-oxo-dGDP phosphatase activity(GO:0044715)
0.0 3.8 GO:0008026 ATP-dependent helicase activity(GO:0008026) purine NTP-dependent helicase activity(GO:0070035)
0.0 3.8 GO:0004842 ubiquitin-protein transferase activity(GO:0004842)
0.1 3.6 GO:0061631 ubiquitin conjugating enzyme activity(GO:0061631) ubiquitin-like protein conjugating enzyme activity(GO:0061650)
0.2 3.5 GO:0030215 semaphorin receptor binding(GO:0030215)
0.1 3.5 GO:0004407 histone deacetylase activity(GO:0004407)

Gene overrepresentation in C2:CP category:

Showing 1 to 20 of 26 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.3 16.8 PID_IL12_2PATHWAY IL12-mediated signaling events
0.2 10.4 PID_AURORA_B_PATHWAY Aurora B signaling
0.2 9.0 PID_FOXM1_PATHWAY FOXM1 transcription factor network
0.3 8.1 PID_SMAD2_3PATHWAY Regulation of cytoplasmic and nuclear SMAD2/3 signaling
0.2 7.2 PID_SYNDECAN_4_PATHWAY Syndecan-4-mediated signaling events
0.2 6.6 PID_AURORA_A_PATHWAY Aurora A signaling
0.2 4.7 PID_BETA_CATENIN_DEG_PATHWAY Degradation of beta catenin
0.1 4.4 PID_HNF3A_PATHWAY FOXA1 transcription factor network
0.1 3.9 PID_ATM_PATHWAY ATM pathway
0.1 3.8 PID_PS1_PATHWAY Presenilin action in Notch and Wnt signaling
0.0 3.7 SIG_INSULIN_RECEPTOR_PATHWAY_IN_CARDIAC_MYOCYTES Genes related to the insulin receptor pathway
0.0 3.2 PID_SMAD2_3NUCLEAR_PATHWAY Regulation of nuclear SMAD2/3 signaling
0.1 3.0 PID_P53_REGULATION_PATHWAY p53 pathway
0.1 2.0 PID_FANCONI_PATHWAY Fanconi anemia pathway
0.1 1.9 PID_CD40_PATHWAY CD40/CD40L signaling
0.0 1.8 PID_AVB3_INTEGRIN_PATHWAY Integrins in angiogenesis
0.1 1.6 PID_DNA_PK_PATHWAY DNA-PK pathway in nonhomologous end joining
0.0 1.6 PID_RB_1PATHWAY Regulation of retinoblastoma protein
0.0 1.6 NABA_ECM_AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.2 1.5 ST_TYPE_I_INTERFERON_PATHWAY Type I Interferon (alpha/beta IFN) Pathway

Gene overrepresentation in C2:CP:REACTOME category:

Showing 1 to 20 of 42 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.3 10.6 REACTOME_ACTIVATION_OF_ATR_IN_RESPONSE_TO_REPLICATION_STRESS Genes involved in Activation of ATR in response to replication stress
0.5 9.1 REACTOME_MITOCHONDRIAL_FATTY_ACID_BETA_OXIDATION Genes involved in Mitochondrial Fatty Acid Beta-Oxidation
0.2 6.7 REACTOME_SYNTHESIS_OF_GLYCOSYLPHOSPHATIDYLINOSITOL_GPI Genes involved in Synthesis of glycosylphosphatidylinositol (GPI)
0.1 6.0 REACTOME_ANTIVIRAL_MECHANISM_BY_IFN_STIMULATED_GENES Genes involved in Antiviral mechanism by IFN-stimulated genes
0.0 6.0 REACTOME_METABOLISM_OF_AMINO_ACIDS_AND_DERIVATIVES Genes involved in Metabolism of amino acids and derivatives
0.1 5.8 REACTOME_MEIOTIC_SYNAPSIS Genes involved in Meiotic Synapsis
0.3 5.0 REACTOME_CYCLIN_A_B1_ASSOCIATED_EVENTS_DURING_G2_M_TRANSITION Genes involved in Cyclin A/B1 associated events during G2/M transition
0.3 4.8 REACTOME_DESTABILIZATION_OF_MRNA_BY_TRISTETRAPROLIN_TTP Genes involved in Destabilization of mRNA by Tristetraprolin (TTP)
0.2 4.0 REACTOME_APC_CDC20_MEDIATED_DEGRADATION_OF_NEK2A Genes involved in APC-Cdc20 mediated degradation of Nek2A
0.1 3.6 REACTOME_SIGNALING_BY_HIPPO Genes involved in Signaling by Hippo
0.1 3.0 REACTOME_TGF_BETA_RECEPTOR_SIGNALING_IN_EMT_EPITHELIAL_TO_MESENCHYMAL_TRANSITION Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.2 2.9 REACTOME_RECEPTOR_LIGAND_BINDING_INITIATES_THE_SECOND_PROTEOLYTIC_CLEAVAGE_OF_NOTCH_RECEPTOR Genes involved in Receptor-ligand binding initiates the second proteolytic cleavage of Notch receptor
0.2 2.9 REACTOME_SYNTHESIS_OF_PIPS_AT_THE_EARLY_ENDOSOME_MEMBRANE Genes involved in Synthesis of PIPs at the early endosome membrane
0.2 2.6 REACTOME_PROLACTIN_RECEPTOR_SIGNALING Genes involved in Prolactin receptor signaling
0.1 2.4 REACTOME_RNA_POL_III_CHAIN_ELONGATION Genes involved in RNA Polymerase III Chain Elongation
0.0 2.3 REACTOME_MITOTIC_PROMETAPHASE Genes involved in Mitotic Prometaphase
0.1 2.2 REACTOME_LIGAND_GATED_ION_CHANNEL_TRANSPORT Genes involved in Ligand-gated ion channel transport
0.1 2.1 REACTOME_CASPASE_MEDIATED_CLEAVAGE_OF_CYTOSKELETAL_PROTEINS Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.1 2.0 REACTOME_FANCONI_ANEMIA_PATHWAY Genes involved in Fanconi Anemia pathway
0.1 1.9 REACTOME_SIGNALING_BY_FGFR1_FUSION_MUTANTS Genes involved in Signaling by FGFR1 fusion mutants