Motif ID: Hivep1

Z-value: 0.868


Transcription factors associated with Hivep1:

Gene SymbolEntrez IDGene Name
Hivep1 ENSMUSG00000021366.7 Hivep1

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Hivep1mm10_v2_chr13_+_42052015_420520720.221.9e-01Click!


Activity profile for motif Hivep1.

activity profile for motif Hivep1


Sorted Z-values histogram for motif Hivep1

Sorted Z-values for motif Hivep1



Network of associatons between targets according to the STRING database.



First level regulatory network of Hivep1

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr3_-_88000350 5.995 ENSMUST00000090971.5
Bcan
brevican
chr10_-_27616895 4.533 ENSMUST00000092639.5
Lama2
laminin, alpha 2
chr2_-_113758638 3.181 ENSMUST00000099575.3
Grem1
gremlin 1
chr3_-_107760221 3.005 ENSMUST00000153114.1
ENSMUST00000118593.1
ENSMUST00000120243.1
Csf1


colony stimulating factor 1 (macrophage)


chr5_-_98030727 2.972 ENSMUST00000031281.9
Antxr2
anthrax toxin receptor 2
chr14_+_51984857 2.908 ENSMUST00000100639.4
ENSMUST00000182909.1
ENSMUST00000182760.1
ENSMUST00000182061.1
ENSMUST00000182193.1
Arhgef40




Rho guanine nucleotide exchange factor (GEF) 40




chr5_-_134747241 2.663 ENSMUST00000015138.9
Eln
elastin
chr14_+_51984826 2.636 ENSMUST00000093813.5
Arhgef40
Rho guanine nucleotide exchange factor (GEF) 40
chr14_+_80000292 2.171 ENSMUST00000088735.3
Olfm4
olfactomedin 4
chr18_+_84088077 2.139 ENSMUST00000060223.2
Zadh2
zinc binding alcohol dehydrogenase, domain containing 2
chr1_-_156204998 2.064 ENSMUST00000015628.3
Fam163a
family with sequence similarity 163, member A
chr17_-_35701937 2.040 ENSMUST00000155628.1
Ddr1
discoidin domain receptor family, member 1
chr17_-_34000257 1.964 ENSMUST00000087189.6
ENSMUST00000173075.1
ENSMUST00000172760.1
ENSMUST00000172912.1
ENSMUST00000025181.10
H2-K1




histocompatibility 2, K1, K region




chr14_+_60732906 1.937 ENSMUST00000162945.1
Spata13
spermatogenesis associated 13
chr11_-_100411874 1.814 ENSMUST00000141840.1
Leprel4
leprecan-like 4
chr17_+_35439155 1.785 ENSMUST00000071951.6
ENSMUST00000078205.7
ENSMUST00000116598.3
ENSMUST00000076256.7
H2-Q7



histocompatibility 2, Q region locus 7



chr11_+_62077018 1.784 ENSMUST00000092415.5
Specc1
sperm antigen with calponin homology and coiled-coil domains 1
chr4_-_82505749 1.747 ENSMUST00000107245.2
ENSMUST00000107246.1
Nfib

nuclear factor I/B

chr1_+_64532790 1.675 ENSMUST00000049932.5
ENSMUST00000087366.4
ENSMUST00000171164.1
Creb1


cAMP responsive element binding protein 1


chr7_-_102250086 1.654 ENSMUST00000106923.1
ENSMUST00000098230.4
Rhog

ras homolog gene family, member G

chr11_+_94211431 1.582 ENSMUST00000041589.5
Tob1
transducer of ErbB-2.1
chr1_+_74791516 1.547 ENSMUST00000006718.8
Wnt10a
wingless related MMTV integration site 10a
chr17_-_33890539 1.534 ENSMUST00000173386.1
Kifc1
kinesin family member C1
chr14_-_34503323 1.519 ENSMUST00000171343.1
Bmpr1a
bone morphogenetic protein receptor, type 1A
chr4_-_133968611 1.507 ENSMUST00000102552.1
Hmgn2
high mobility group nucleosomal binding domain 2
chr17_-_35702297 1.491 ENSMUST00000135078.1
Ddr1
discoidin domain receptor family, member 1
chr11_+_70657196 1.431 ENSMUST00000157027.1
ENSMUST00000072841.5
ENSMUST00000108548.1
ENSMUST00000126241.1
Eno3



enolase 3, beta muscle



chr10_-_116972609 1.399 ENSMUST00000092165.4
Gm10271
predicted gene 10271
chr2_-_181459364 1.390 ENSMUST00000155535.1
ENSMUST00000029106.6
ENSMUST00000087409.3
Zbtb46


zinc finger and BTB domain containing 46


chr6_-_97487801 1.381 ENSMUST00000113353.1
ENSMUST00000032146.7
Frmd4b

FERM domain containing 4B

chr17_-_33890584 1.308 ENSMUST00000114361.2
ENSMUST00000173492.1
Kifc1

kinesin family member C1

chr2_+_61578549 1.305 ENSMUST00000112502.1
ENSMUST00000078074.2
Tank

TRAF family member-associated Nf-kappa B activator

chr15_-_102529025 1.228 ENSMUST00000096143.1
Atf7
activating transcription factor 7
chr17_+_35379608 1.152 ENSMUST00000081435.4
H2-Q4
histocompatibility 2, Q region locus 4
chr2_-_104816696 1.151 ENSMUST00000117237.1
Qser1
glutamine and serine rich 1
chr4_-_40239779 1.151 ENSMUST00000037907.6
Ddx58
DEAD (Asp-Glu-Ala-Asp) box polypeptide 58
chr7_+_25681158 1.111 ENSMUST00000108403.3
B9d2
B9 protein domain 2
chr10_-_49788743 1.109 ENSMUST00000105483.1
ENSMUST00000105487.1
Grik2

glutamate receptor, ionotropic, kainate 2 (beta 2)

chr7_+_97579868 1.107 ENSMUST00000042399.7
ENSMUST00000107153.1
Rsf1

remodeling and spacing factor 1

chr17_-_35702040 1.077 ENSMUST00000166980.2
ENSMUST00000145900.1
Ddr1

discoidin domain receptor family, member 1

chr6_+_55336424 1.028 ENSMUST00000004774.3
Aqp1
aquaporin 1
chr7_-_19629355 1.021 ENSMUST00000049912.8
ENSMUST00000094762.3
ENSMUST00000098754.4
Relb


avian reticuloendotheliosis viral (v-rel) oncogene related B


chr9_+_95857597 1.000 ENSMUST00000034980.7
Atr
ataxia telangiectasia and Rad3 related
chr15_-_89170688 0.999 ENSMUST00000060808.9
Plxnb2
plexin B2
chr5_+_90759299 0.987 ENSMUST00000031318.4
Cxcl5
chemokine (C-X-C motif) ligand 5
chr12_-_98577940 0.954 ENSMUST00000110113.1
Kcnk10
potassium channel, subfamily K, member 10
chr11_-_77078404 0.952 ENSMUST00000102494.1
Ccdc55
coiled-coil domain containing 55
chr11_-_70656467 0.948 ENSMUST00000131642.1
Gm12319
predicted gene 12319
chr10_+_7681197 0.938 ENSMUST00000165952.1
Lats1
large tumor suppressor
chr2_+_16356294 0.927 ENSMUST00000028081.6
Plxdc2
plexin domain containing 2
chr4_-_43558386 0.917 ENSMUST00000130353.1
Tln1
talin 1
chr17_+_26917091 0.891 ENSMUST00000078961.4
Kifc5b
kinesin family member C5B
chr8_+_90828820 0.877 ENSMUST00000109614.2
ENSMUST00000048665.6
Chd9

chromodomain helicase DNA binding protein 9

chr7_+_27605797 0.865 ENSMUST00000143499.1
ENSMUST00000108343.1
Akt2

thymoma viral proto-oncogene 2

chr10_+_115384951 0.853 ENSMUST00000036044.8
Zfc3h1
zinc finger, C3H1-type containing
chr7_+_27605847 0.843 ENSMUST00000051356.5
Akt2
thymoma viral proto-oncogene 2
chr7_-_127345314 0.829 ENSMUST00000060783.5
Zfp768
zinc finger protein 768
chr3_-_65958236 0.828 ENSMUST00000029416.7
Ccnl1
cyclin L1
chr4_-_108406676 0.803 ENSMUST00000184609.1
Gpx7
glutathione peroxidase 7
chr10_+_127195240 0.778 ENSMUST00000181578.1
F420014N23Rik
RIKEN cDNA F420014N23 gene
chr7_+_80186835 0.760 ENSMUST00000107383.1
ENSMUST00000032754.7
Sema4b

sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B

chr13_+_44730726 0.758 ENSMUST00000173704.1
ENSMUST00000044608.7
ENSMUST00000173367.1
Jarid2


jumonji, AT rich interactive domain 2


chr5_+_138280516 0.754 ENSMUST00000048028.8
Stag3
stromal antigen 3
chr2_+_177508570 0.750 ENSMUST00000108940.2
Gm14403
predicted gene 14403
chr3_-_115888086 0.749 ENSMUST00000067500.5
A930005H10Rik
RIKEN cDNA A930005H10 gene
chr4_-_133967953 0.730 ENSMUST00000102553.4
Hmgn2
high mobility group nucleosomal binding domain 2
chrX_-_155216338 0.712 ENSMUST00000112551.3
Sat1
spermidine/spermine N1-acetyl transferase 1
chr1_-_36273425 0.698 ENSMUST00000056946.6
Neurl3
neuralized homolog 3 homolog (Drosophila)
chr2_+_29869484 0.693 ENSMUST00000047521.6
ENSMUST00000134152.1
Cercam

cerebral endothelial cell adhesion molecule

chr12_+_98920567 0.680 ENSMUST00000085109.3
ENSMUST00000079146.6
Ttc8

tetratricopeptide repeat domain 8

chr4_-_40239700 0.664 ENSMUST00000142055.1
Ddx58
DEAD (Asp-Glu-Ala-Asp) box polypeptide 58
chrX_-_8206475 0.654 ENSMUST00000089403.3
ENSMUST00000077595.5
ENSMUST00000089402.3
ENSMUST00000082320.5
Porcn



porcupine homolog (Drosophila)



chr6_+_120666388 0.654 ENSMUST00000112686.1
Cecr2
cat eye syndrome chromosome region, candidate 2
chr16_+_32914094 0.635 ENSMUST00000023491.6
ENSMUST00000170899.1
ENSMUST00000171118.1
ENSMUST00000170201.1
ENSMUST00000165616.1
ENSMUST00000135193.2
Lrch3





leucine-rich repeats and calponin homology (CH) domain containing 3





chr2_+_16356744 0.634 ENSMUST00000114703.3
Plxdc2
plexin domain containing 2
chr18_+_37496997 0.629 ENSMUST00000059571.5
Pcdhb19
protocadherin beta 19
chr4_-_43031429 0.619 ENSMUST00000136326.1
Stoml2
stomatin (Epb7.2)-like 2
chr17_+_45555693 0.609 ENSMUST00000024742.7
Nfkbie
nuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor, epsilon
chr17_+_35424842 0.531 ENSMUST00000174699.1
H2-Q6
histocompatibility 2, Q region locus 6
chr18_+_37477768 0.526 ENSMUST00000051442.5
Pcdhb16
protocadherin beta 16
chr3_+_7612702 0.526 ENSMUST00000181286.1
Gm16685
predicted gene, 16685
chr11_+_60699758 0.511 ENSMUST00000108719.3
Llgl1
lethal giant larvae homolog 1 (Drosophila)
chr11_+_101176041 0.495 ENSMUST00000103109.3
Cntnap1
contactin associated protein-like 1
chr2_+_130405256 0.494 ENSMUST00000110281.1
ENSMUST00000028898.3
1700020A23Rik

RIKEN cDNA 1700020A23 gene

chr3_-_53657339 0.494 ENSMUST00000091137.4
Frem2
Fras1 related extracellular matrix protein 2
chr19_-_4615647 0.490 ENSMUST00000113822.2
Lrfn4
leucine rich repeat and fibronectin type III domain containing 4
chr4_-_43031370 0.471 ENSMUST00000138030.1
Stoml2
stomatin (Epb7.2)-like 2
chr10_+_80755196 0.465 ENSMUST00000105336.2
Dot1l
DOT1-like, histone H3 methyltransferase (S. cerevisiae)
chr7_+_128265675 0.462 ENSMUST00000118169.1
ENSMUST00000142841.1
Slc5a2

solute carrier family 5 (sodium/glucose cotransporter), member 2

chr19_-_4615453 0.454 ENSMUST00000053597.2
Lrfn4
leucine rich repeat and fibronectin type III domain containing 4
chr1_-_155972887 0.432 ENSMUST00000138762.1
ENSMUST00000124495.1
Cep350

centrosomal protein 350

chr9_+_55326913 0.430 ENSMUST00000085754.3
ENSMUST00000034862.4
AI118078

expressed sequence AI118078

chr2_-_5063932 0.429 ENSMUST00000027986.4
Optn
optineurin
chr15_+_101266839 0.429 ENSMUST00000023779.6
Nr4a1
nuclear receptor subfamily 4, group A, member 1
chr2_-_5063996 0.426 ENSMUST00000114996.1
Optn
optineurin
chr10_-_95415484 0.412 ENSMUST00000172070.1
ENSMUST00000150432.1
Socs2

suppressor of cytokine signaling 2

chr6_+_83034173 0.410 ENSMUST00000000707.2
ENSMUST00000101257.3
Loxl3

lysyl oxidase-like 3

chr14_+_55560904 0.403 ENSMUST00000072530.4
ENSMUST00000128490.1
Dcaf11

DDB1 and CUL4 associated factor 11

chr10_-_127522428 0.394 ENSMUST00000026470.4
Shmt2
serine hydroxymethyltransferase 2 (mitochondrial)
chr14_-_45529964 0.367 ENSMUST00000150660.1
Fermt2
fermitin family homolog 2 (Drosophila)
chr19_-_50678642 0.357 ENSMUST00000072685.6
ENSMUST00000164039.2
Sorcs1

VPS10 domain receptor protein SORCS 1

chr11_+_51263114 0.353 ENSMUST00000093132.6
ENSMUST00000109113.1
Clk4

CDC like kinase 4

chr7_-_101302020 0.350 ENSMUST00000122116.1
ENSMUST00000120267.1
Atg16l2

autophagy related 16-like 2 (S. cerevisiae)

chr14_+_55561060 0.339 ENSMUST00000117701.1
Dcaf11
DDB1 and CUL4 associated factor 11
chr10_+_127380799 0.327 ENSMUST00000111628.2
R3hdm2
R3H domain containing 2
chr2_+_118900377 0.308 ENSMUST00000151162.1
Bahd1
bromo adjacent homology domain containing 1
chr14_+_55560480 0.307 ENSMUST00000121622.1
ENSMUST00000143431.1
ENSMUST00000150481.1
Dcaf11


DDB1 and CUL4 associated factor 11


chr1_-_172590463 0.284 ENSMUST00000065679.6
Slamf8
SLAM family member 8
chr10_-_95415283 0.279 ENSMUST00000119917.1
Socs2
suppressor of cytokine signaling 2
chr17_+_35424870 0.279 ENSMUST00000113879.3
H2-Q6
histocompatibility 2, Q region locus 6
chr1_+_135132693 0.267 ENSMUST00000049449.4
Ptpn7
protein tyrosine phosphatase, non-receptor type 7
chr7_-_99626936 0.248 ENSMUST00000178124.1
Gm4980
predicted gene 4980
chr7_+_99535652 0.247 ENSMUST00000032995.8
ENSMUST00000162404.1
Arrb1

arrestin, beta 1

chr15_-_79164477 0.237 ENSMUST00000040019.4
Sox10
SRY-box containing gene 10
chr14_+_53324632 0.230 ENSMUST00000178100.1
Trav7n-6
T cell receptor alpha variable 7N-6
chr6_+_113307160 0.215 ENSMUST00000113122.1
ENSMUST00000113119.1
ENSMUST00000113121.1
ENSMUST00000113117.1
Brpf1



bromodomain and PHD finger containing, 1



chr5_-_145201829 0.214 ENSMUST00000162220.1
ENSMUST00000031632.8
Zkscan14

zinc finger with KRAB and SCAN domains 14

chr19_-_58454435 0.214 ENSMUST00000169850.1
Gfra1
glial cell line derived neurotrophic factor family receptor alpha 1
chr18_+_37742088 0.212 ENSMUST00000003599.6
Pcdhga9
protocadherin gamma subfamily A, 9
chr11_-_22001605 0.211 ENSMUST00000006071.7
Otx1
orthodenticle homolog 1 (Drosophila)
chr10_+_119992916 0.209 ENSMUST00000105261.2
Grip1
glutamate receptor interacting protein 1
chrX_-_134600976 0.204 ENSMUST00000033621.6
Gla
galactosidase, alpha
chr6_-_48841373 0.204 ENSMUST00000166247.1
Tmem176b
transmembrane protein 176B
chr6_-_48841098 0.201 ENSMUST00000101429.4
Tmem176b
transmembrane protein 176B
chr17_+_74717743 0.190 ENSMUST00000024882.6
Ttc27
tetratricopeptide repeat domain 27
chr6_-_48840988 0.187 ENSMUST00000164733.1
Tmem176b
transmembrane protein 176B
chr19_-_5845471 0.184 ENSMUST00000174287.1
ENSMUST00000173672.1
Neat1

nuclear paraspeckle assembly transcript 1 (non-protein coding)

chr11_+_97799772 0.183 ENSMUST00000129558.1
Lasp1
LIM and SH3 protein 1
chr2_-_104257400 0.174 ENSMUST00000141159.1
D430041D05Rik
RIKEN cDNA D430041D05 gene
chr19_-_58454580 0.162 ENSMUST00000129100.1
ENSMUST00000123957.1
Gfra1

glial cell line derived neurotrophic factor family receptor alpha 1

chr6_-_122820606 0.160 ENSMUST00000181317.1
Gm26826
predicted gene, 26826
chr7_+_99535439 0.151 ENSMUST00000098266.2
ENSMUST00000179755.1
Arrb1

arrestin, beta 1

chr1_-_175688353 0.149 ENSMUST00000104984.1
Chml
choroideremia-like
chr16_+_97997313 0.147 ENSMUST00000122450.1
B230307C23Rik
RIKEN cDNA B230307C23 gene
chr17_+_26933070 0.144 ENSMUST00000073724.5
Phf1
PHD finger protein 1
chr11_-_89418948 0.128 ENSMUST00000050983.1
4932411E22Rik
RIKEN cDNA 4932411E22 gene
chr11_+_78188737 0.127 ENSMUST00000108322.2
Rab34
RAB34, member of RAS oncogene family
chr19_-_58455161 0.126 ENSMUST00000135730.1
ENSMUST00000152507.1
Gfra1

glial cell line derived neurotrophic factor family receptor alpha 1

chr10_+_127380591 0.122 ENSMUST00000166820.1
R3hdm2
R3H domain containing 2
chr4_+_155562348 0.121 ENSMUST00000030939.7
Nadk
NAD kinase
chr4_+_41135743 0.111 ENSMUST00000040008.3
Ube2r2
ubiquitin-conjugating enzyme E2R 2
chr4_+_115057410 0.103 ENSMUST00000136946.1
Tal1
T cell acute lymphocytic leukemia 1
chr1_+_39900883 0.102 ENSMUST00000163854.2
ENSMUST00000168431.1
Map4k4

mitogen-activated protein kinase kinase kinase kinase 4

chr7_+_12977834 0.101 ENSMUST00000108537.1
ENSMUST00000108535.1
ENSMUST00000045810.7
Zfp446


zinc finger protein 446


chr5_-_138170992 0.093 ENSMUST00000139983.1
Mcm7
minichromosome maintenance deficient 7 (S. cerevisiae)
chr11_+_78188806 0.088 ENSMUST00000056241.5
Rab34
RAB34, member of RAS oncogene family
chr6_+_83057844 0.081 ENSMUST00000077502.2
Dqx1
DEAQ RNA-dependent ATPase
chr18_+_38993126 0.080 ENSMUST00000097593.2
Arhgap26
Rho GTPase activating protein 26
chrX_-_8132770 0.079 ENSMUST00000130832.1
ENSMUST00000033506.6
ENSMUST00000115623.1
ENSMUST00000153839.1
Wdr13



WD repeat domain 13



chr5_+_86804508 0.075 ENSMUST00000038384.7
Ythdc1
YTH domain containing 1
chr19_-_50678485 0.075 ENSMUST00000111756.3
Sorcs1
VPS10 domain receptor protein SORCS 1
chr12_-_55492587 0.070 ENSMUST00000021413.7
Nfkbia
nuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor, alpha
chr16_+_38089001 0.049 ENSMUST00000023507.6
Gsk3b
glycogen synthase kinase 3 beta
chr2_+_23321246 0.049 ENSMUST00000102945.1
Nxph2
neurexophilin 2
chr1_+_58646608 0.043 ENSMUST00000081455.4
Gm10068
predicted gene 10068
chr18_+_37484955 0.032 ENSMUST00000053856.4
Pcdhb17
protocadherin beta 17
chr14_+_50807915 0.032 ENSMUST00000036126.5
Parp2
poly (ADP-ribose) polymerase family, member 2
chr17_+_91236787 0.030 ENSMUST00000057074.8
Gm6741
predicted gene 6741
chr11_+_93098404 0.016 ENSMUST00000107859.1
ENSMUST00000042943.6
ENSMUST00000107861.1
ENSMUST00000107858.2
Car10



carbonic anhydrase 10



chr12_-_82496537 0.001 ENSMUST00000179295.1
Gm5435
predicted gene 5435

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
1.2 6.2 GO:0002158 osteoclast proliferation(GO:0002158)
0.9 2.8 GO:0072382 minus-end-directed vesicle transport along microtubule(GO:0072382)
0.9 4.5 GO:0032224 positive regulation of synaptic transmission, cholinergic(GO:0032224)
0.6 1.7 GO:0032916 positive regulation of transforming growth factor beta3 production(GO:0032916)
0.5 1.0 GO:0046878 positive regulation of saliva secretion(GO:0046878)
0.5 1.5 GO:0021998 neural plate mediolateral regionalization(GO:0021998) mesoderm structural organization(GO:0048338) paraxial mesoderm structural organization(GO:0048352) positive regulation of cardiac ventricle development(GO:1904414)
0.5 2.0 GO:0002484 antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway(GO:0002484) antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent(GO:0002485)
0.5 1.8 GO:0009597 detection of virus(GO:0009597)
0.4 1.7 GO:2000795 negative regulation of epithelial cell proliferation involved in lung morphogenesis(GO:2000795)
0.4 4.6 GO:0061302 smooth muscle cell-matrix adhesion(GO:0061302)
0.4 1.1 GO:1990046 positive regulation of mitochondrial DNA replication(GO:0090297) regulation of cardiolipin metabolic process(GO:1900208) positive regulation of cardiolipin metabolic process(GO:1900210) stress-induced mitochondrial fusion(GO:1990046)
0.3 1.0 GO:1904884 telomerase catalytic core complex assembly(GO:1904868) regulation of telomerase catalytic core complex assembly(GO:1904882) positive regulation of telomerase catalytic core complex assembly(GO:1904884)
0.3 1.0 GO:0070944 neutrophil mediated killing of bacterium(GO:0070944)
0.3 1.3 GO:2000158 positive regulation of ubiquitin-specific protease activity(GO:2000158)
0.3 0.9 GO:0001827 inner cell mass cell fate commitment(GO:0001827)
0.3 1.7 GO:0097473 cellular response to light intensity(GO:0071484) cellular response to high light intensity(GO:0071486) retinal rod cell apoptotic process(GO:0097473)
0.3 2.0 GO:2001199 negative regulation of dendritic cell differentiation(GO:2001199)
0.2 0.7 GO:0032918 polyamine acetylation(GO:0032917) spermidine acetylation(GO:0032918)
0.2 0.9 GO:0001920 negative regulation of receptor recycling(GO:0001920)
0.2 0.8 GO:0007066 female meiosis sister chromatid cohesion(GO:0007066)
0.2 1.6 GO:1902373 negative regulation of mRNA catabolic process(GO:1902373)
0.2 1.5 GO:0042487 regulation of odontogenesis of dentin-containing tooth(GO:0042487)
0.2 1.1 GO:0016584 nucleosome positioning(GO:0016584)
0.1 0.5 GO:0002175 protein localization to paranode region of axon(GO:0002175)
0.1 0.6 GO:0032329 serine transport(GO:0032329)
0.1 0.5 GO:0034729 histone H3-K79 methylation(GO:0034729)
0.1 0.9 GO:0007016 cytoskeletal anchoring at plasma membrane(GO:0007016)
0.1 3.7 GO:0002474 antigen processing and presentation of peptide antigen via MHC class I(GO:0002474)
0.1 0.4 GO:2000319 negative regulation of T-helper 17 type immune response(GO:2000317) regulation of T-helper 17 cell differentiation(GO:2000319) negative regulation of T-helper 17 cell differentiation(GO:2000320)
0.1 1.1 GO:0051967 negative regulation of synaptic transmission, glutamatergic(GO:0051967)
0.1 0.4 GO:0006545 glycine biosynthetic process(GO:0006545)
0.1 1.0 GO:0030322 stabilization of membrane potential(GO:0030322)
0.1 0.3 GO:2000508 regulation of dendritic cell chemotaxis(GO:2000508)
0.1 0.5 GO:1904659 glucose transmembrane transport(GO:1904659)
0.1 0.8 GO:1901409 positive regulation of phosphorylation of RNA polymerase II C-terminal domain(GO:1901409)
0.1 2.2 GO:0040034 regulation of development, heterochronic(GO:0040034)
0.1 1.0 GO:0043011 myeloid dendritic cell differentiation(GO:0043011)
0.1 0.7 GO:0001842 neural fold formation(GO:0001842)
0.1 0.4 GO:0042699 follicle-stimulating hormone signaling pathway(GO:0042699)
0.1 1.7 GO:1900027 regulation of ruffle assembly(GO:1900027)
0.1 3.0 GO:1901998 toxin transport(GO:1901998)
0.1 0.2 GO:0010626 negative regulation of Schwann cell proliferation(GO:0010626)
0.1 0.4 GO:0044034 negative stranded viral RNA replication(GO:0039689) multi-organism biosynthetic process(GO:0044034)
0.1 0.8 GO:0051574 positive regulation of histone H3-K9 methylation(GO:0051574)
0.1 5.1 GO:0021766 hippocampus development(GO:0021766)
0.0 2.2 GO:1900026 positive regulation of substrate adhesion-dependent cell spreading(GO:1900026)
0.0 0.5 GO:0061469 regulation of type B pancreatic cell proliferation(GO:0061469)
0.0 7.5 GO:0035023 regulation of Rho protein signal transduction(GO:0035023)
0.0 0.2 GO:1905169 protein localization to phagocytic vesicle(GO:1905161) regulation of protein localization to phagocytic vesicle(GO:1905169) positive regulation of protein localization to phagocytic vesicle(GO:1905171)
0.0 0.7 GO:0060219 camera-type eye photoreceptor cell differentiation(GO:0060219)
0.0 0.7 GO:0071378 growth hormone receptor signaling pathway(GO:0060396) cellular response to growth hormone stimulus(GO:0071378)
0.0 0.2 GO:0048852 diencephalon morphogenesis(GO:0048852)
0.0 0.1 GO:0060217 hemangioblast cell differentiation(GO:0060217)
0.0 0.5 GO:0035090 maintenance of apical/basal cell polarity(GO:0035090)
0.0 1.9 GO:0045599 negative regulation of fat cell differentiation(GO:0045599)
0.0 1.0 GO:0071526 semaphorin-plexin signaling pathway(GO:0071526)
0.0 0.8 GO:0050919 negative chemotaxis(GO:0050919)
0.0 0.2 GO:0051001 negative regulation of nitric-oxide synthase activity(GO:0051001)
0.0 0.1 GO:0061086 negative regulation of histone H3-K27 methylation(GO:0061086)
0.0 0.5 GO:0016339 calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0016339)
0.0 0.4 GO:0034453 microtubule anchoring(GO:0034453)
0.0 0.3 GO:0031507 heterochromatin assembly(GO:0031507)
0.0 0.1 GO:0006741 NADP biosynthetic process(GO:0006741)
0.0 1.6 GO:0043149 contractile actin filament bundle assembly(GO:0030038) stress fiber assembly(GO:0043149)
0.0 0.1 GO:0018344 protein geranylgeranylation(GO:0018344)
0.0 0.1 GO:0070427 nucleotide-binding oligomerization domain containing 1 signaling pathway(GO:0070427)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
1.0 3.0 GO:1990682 CSF1-CSF1R complex(GO:1990682)
0.9 2.7 GO:0071953 elastic fiber(GO:0071953)
0.5 5.7 GO:0042612 MHC class I protein complex(GO:0042612)
0.3 1.0 GO:0032127 dense core granule membrane(GO:0032127)
0.3 0.8 GO:0000802 transverse filament(GO:0000802)
0.2 1.1 GO:0032983 kainate selective glutamate receptor complex(GO:0032983)
0.2 2.2 GO:0042581 specific granule(GO:0042581)
0.2 0.7 GO:0090537 CERF complex(GO:0090537)
0.2 1.4 GO:0000015 phosphopyruvate hydratase complex(GO:0000015)
0.1 1.0 GO:0033256 I-kappaB/NF-kappaB complex(GO:0033256)
0.1 2.8 GO:0031616 spindle pole centrosome(GO:0031616)
0.1 1.7 GO:0032593 insulin-responsive compartment(GO:0032593)
0.1 0.4 GO:0070552 BRISC complex(GO:0070552)
0.1 1.7 GO:0044300 cerebellar mossy fiber(GO:0044300)
0.1 1.6 GO:0030014 CCR4-NOT complex(GO:0030014)
0.1 1.5 GO:0005605 basal lamina(GO:0005605)
0.1 1.1 GO:0036038 MKS complex(GO:0036038)
0.1 1.1 GO:0031010 ISWI-type complex(GO:0031010)
0.1 0.7 GO:0034464 BBSome(GO:0034464)
0.1 6.5 GO:0031225 anchored component of membrane(GO:0031225)
0.0 0.5 GO:0000137 Golgi cis cisterna(GO:0000137)
0.0 0.8 GO:0005665 DNA-directed RNA polymerase II, core complex(GO:0005665)
0.0 1.7 GO:0005719 nuclear euchromatin(GO:0005719)
0.0 0.9 GO:0035098 ESC/E(Z) complex(GO:0035098)
0.0 1.0 GO:0001741 XY body(GO:0001741)
0.0 0.2 GO:0070776 H3 histone acetyltransferase complex(GO:0070775) MOZ/MORF histone acetyltransferase complex(GO:0070776)
0.0 0.1 GO:0033193 Lsd1/2 complex(GO:0033193)
0.0 0.3 GO:0005677 chromatin silencing complex(GO:0005677)
0.0 0.1 GO:0005968 Rab-protein geranylgeranyltransferase complex(GO:0005968)
0.0 0.2 GO:0031315 extrinsic component of mitochondrial outer membrane(GO:0031315)
0.0 2.8 GO:0032587 ruffle membrane(GO:0032587)
0.0 1.0 GO:0080008 Cul4-RING E3 ubiquitin ligase complex(GO:0080008)
0.0 0.4 GO:0031143 pseudopodium(GO:0031143)
0.0 1.1 GO:0008180 COP9 signalosome(GO:0008180)
0.0 0.2 GO:0042382 paraspeckles(GO:0042382)
0.0 0.7 GO:0032281 AMPA glutamate receptor complex(GO:0032281)
0.0 2.2 GO:0001726 ruffle(GO:0001726)
0.0 0.2 GO:0033270 paranode region of axon(GO:0033270)
0.0 1.5 GO:0005901 caveola(GO:0005901)
0.0 4.6 GO:0016323 basolateral plasma membrane(GO:0016323)
0.0 0.8 GO:0008023 transcription elongation factor complex(GO:0008023)
0.0 0.5 GO:0032391 photoreceptor connecting cilium(GO:0032391)
0.0 0.4 GO:0000421 autophagosome membrane(GO:0000421)
0.0 0.9 GO:0005871 kinesin complex(GO:0005871)
0.0 0.5 GO:0031526 brush border membrane(GO:0031526)
0.0 2.1 GO:0005777 peroxisome(GO:0005777) microbody(GO:0042579)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 2.1 GO:0036132 13-prostaglandin reductase activity(GO:0036132) 15-oxoprostaglandin 13-oxidase activity(GO:0047522)
0.6 1.7 GO:0001225 RNA polymerase II transcription coactivator binding(GO:0001225)
0.5 4.6 GO:0038062 protein tyrosine kinase collagen receptor activity(GO:0038062)
0.4 5.7 GO:0030881 beta-2-microglobulin binding(GO:0030881)
0.3 3.1 GO:0036122 BMP binding(GO:0036122)
0.3 6.0 GO:0005540 hyaluronic acid binding(GO:0005540)
0.3 1.3 GO:0035800 deubiquitinase activator activity(GO:0035800)
0.3 1.5 GO:0098821 BMP receptor activity(GO:0098821)
0.2 0.7 GO:0004145 diamine N-acetyltransferase activity(GO:0004145)
0.2 1.0 GO:0015166 polyol transmembrane transporter activity(GO:0015166) glycerol transmembrane transporter activity(GO:0015168)
0.2 2.8 GO:0008569 ATP-dependent microtubule motor activity, minus-end-directed(GO:0008569)
0.2 0.8 GO:0004096 catalase activity(GO:0004096)
0.2 1.1 GO:0015277 kainate selective glutamate receptor activity(GO:0015277)
0.2 1.0 GO:0032405 MutLalpha complex binding(GO:0032405) MutSalpha complex binding(GO:0032407)
0.2 1.4 GO:0004634 phosphopyruvate hydratase activity(GO:0004634)
0.2 1.1 GO:1901612 phosphatidylglycerol binding(GO:1901611) cardiolipin binding(GO:1901612)
0.1 0.7 GO:0008269 JAK pathway signal transduction adaptor activity(GO:0008269)
0.1 0.4 GO:0031896 V2 vasopressin receptor binding(GO:0031896)
0.1 0.4 GO:0008732 threonine aldolase activity(GO:0004793) L-allo-threonine aldolase activity(GO:0008732)
0.1 0.4 GO:0004720 protein-lysine 6-oxidase activity(GO:0004720)
0.1 0.9 GO:0030274 LIM domain binding(GO:0030274)
0.1 2.7 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.1 0.9 GO:0001025 RNA polymerase III transcription factor binding(GO:0001025)
0.1 1.0 GO:0022841 potassium ion leak channel activity(GO:0022841)
0.1 1.0 GO:0017154 semaphorin receptor activity(GO:0017154)
0.1 7.5 GO:0005089 Rho guanyl-nucleotide exchange factor activity(GO:0005089)
0.1 0.2 GO:0010484 H3 histone acetyltransferase activity(GO:0010484)
0.0 1.7 GO:0001106 RNA polymerase II transcription corepressor activity(GO:0001106)
0.0 1.5 GO:0005109 frizzled binding(GO:0005109)
0.0 0.2 GO:0016936 galactoside binding(GO:0016936)
0.0 3.0 GO:0008083 growth factor activity(GO:0008083)
0.0 0.7 GO:0017147 Wnt-protein binding(GO:0017147)
0.0 1.1 GO:0043015 gamma-tubulin binding(GO:0043015)
0.0 0.1 GO:0004111 creatine kinase activity(GO:0004111)
0.0 1.8 GO:0003725 double-stranded RNA binding(GO:0003725)
0.0 0.8 GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity(GO:0016538)
0.0 1.3 GO:0030971 receptor tyrosine kinase binding(GO:0030971)
0.0 1.2 GO:0051019 mitogen-activated protein kinase binding(GO:0051019)
0.0 1.7 GO:0005080 protein kinase C binding(GO:0005080)
0.0 0.7 GO:0001103 RNA polymerase II repressing transcription factor binding(GO:0001103)
0.0 0.9 GO:0030331 estrogen receptor binding(GO:0030331)
0.0 0.8 GO:0032452 histone demethylase activity(GO:0032452)
0.0 0.9 GO:0003777 microtubule motor activity(GO:0003777)
0.0 0.5 GO:0018024 histone-lysine N-methyltransferase activity(GO:0018024)
0.0 0.3 GO:1990841 promoter-specific chromatin binding(GO:1990841)
0.0 0.2 GO:0030159 receptor signaling complex scaffold activity(GO:0030159)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 4.5 PID_INTEGRIN4_PATHWAY Alpha6 beta4 integrin-ligand interactions
0.3 3.0 SA_MMP_CYTOKINE_CONNECTION Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.2 6.0 NABA_PROTEOGLYCANS Genes encoding proteoglycans
0.2 3.0 PID_ANTHRAX_PATHWAY Cellular roles of Anthrax toxin
0.1 1.7 PID_LPA4_PATHWAY LPA4-mediated signaling events
0.1 4.4 PID_BMP_PATHWAY BMP receptor signaling
0.1 0.7 PID_INTEGRIN_A9B1_PATHWAY Alpha9 beta1 integrin signaling events
0.1 1.7 SA_TRKA_RECEPTOR The TrkA receptor binds nerve growth factor to activate MAP kinase pathways and promote cell growth.
0.1 1.0 PID_CIRCADIAN_PATHWAY Circadian rhythm pathway
0.0 1.9 PID_CDC42_REG_PATHWAY Regulation of CDC42 activity
0.0 1.7 PID_HNF3A_PATHWAY FOXA1 transcription factor network
0.0 1.7 PID_ILK_PATHWAY Integrin-linked kinase signaling
0.0 0.9 PID_NECTIN_PATHWAY Nectin adhesion pathway
0.0 3.8 NABA_ECM_AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.0 0.3 PID_TCR_RAS_PATHWAY Ras signaling in the CD4+ TCR pathway
0.0 1.2 PID_RB_1PATHWAY Regulation of retinoblastoma protein
0.0 0.7 PID_IL2_1PATHWAY IL2-mediated signaling events
0.0 1.0 PID_IL12_2PATHWAY IL12-mediated signaling events
0.0 0.5 PID_RET_PATHWAY Signaling events regulated by Ret tyrosine kinase
0.0 1.9 WNT_SIGNALING Genes related to Wnt-mediated signal transduction
0.0 0.4 PID_IL8_CXCR1_PATHWAY IL8- and CXCR1-mediated signaling events
0.0 0.1 PID_IL23_PATHWAY IL23-mediated signaling events

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 6.0 REACTOME_CS_DS_DEGRADATION Genes involved in CS/DS degradation
0.2 3.1 REACTOME_TRAF6_MEDIATED_IRF7_ACTIVATION Genes involved in TRAF6 mediated IRF7 activation
0.1 1.0 REACTOME_TANDEM_PORE_DOMAIN_POTASSIUM_CHANNELS Genes involved in Tandem pore domain potassium channels
0.1 1.0 REACTOME_PASSIVE_TRANSPORT_BY_AQUAPORINS Genes involved in Passive Transport by Aquaporins
0.1 1.7 REACTOME_NEGATIVE_REGULATION_OF_THE_PI3K_AKT_NETWORK Genes involved in Negative regulation of the PI3K/AKT network
0.1 2.8 REACTOME_KINESINS Genes involved in Kinesins
0.1 1.0 REACTOME_G2_M_DNA_DAMAGE_CHECKPOINT Genes involved in G2/M DNA damage checkpoint
0.1 1.7 REACTOME_PKA_MEDIATED_PHOSPHORYLATION_OF_CREB Genes involved in PKA-mediated phosphorylation of CREB
0.1 1.7 REACTOME_RNA_POL_III_TRANSCRIPTION_TERMINATION Genes involved in RNA Polymerase III Transcription Termination
0.1 1.1 REACTOME_IONOTROPIC_ACTIVITY_OF_KAINATE_RECEPTORS Genes involved in Ionotropic activity of Kainate Receptors
0.1 0.9 REACTOME_SEMA3A_PLEXIN_REPULSION_SIGNALING_BY_INHIBITING_INTEGRIN_ADHESION Genes involved in SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion
0.1 1.7 REACTOME_SEMA4D_INDUCED_CELL_MIGRATION_AND_GROWTH_CONE_COLLAPSE Genes involved in Sema4D induced cell migration and growth-cone collapse
0.0 0.7 REACTOME_METABOLISM_OF_POLYAMINES Genes involved in Metabolism of polyamines
0.0 1.3 REACTOME_SIGNALING_BY_BMP Genes involved in Signaling by BMP
0.0 1.4 REACTOME_GLUCONEOGENESIS Genes involved in Gluconeogenesis
0.0 0.9 REACTOME_SIGNALING_BY_HIPPO Genes involved in Signaling by Hippo
0.0 0.7 REACTOME_GROWTH_HORMONE_RECEPTOR_SIGNALING Genes involved in Growth hormone receptor signaling
0.0 1.1 REACTOME_DEPOSITION_OF_NEW_CENPA_CONTAINING_NUCLEOSOMES_AT_THE_CENTROMERE Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere
0.0 0.8 REACTOME_MEIOTIC_SYNAPSIS Genes involved in Meiotic Synapsis
0.0 1.5 REACTOME_INTEGRIN_CELL_SURFACE_INTERACTIONS Genes involved in Integrin cell surface interactions
0.0 0.4 REACTOME_CELL_EXTRACELLULAR_MATRIX_INTERACTIONS Genes involved in Cell-extracellular matrix interactions
0.0 1.1 REACTOME_MITOTIC_PROMETAPHASE Genes involved in Mitotic Prometaphase
0.0 0.5 REACTOME_NCAM1_INTERACTIONS Genes involved in NCAM1 interactions
0.0 0.3 REACTOME_PIP3_ACTIVATES_AKT_SIGNALING Genes involved in PIP3 activates AKT signaling
0.0 0.4 REACTOME_ACTIVATED_NOTCH1_TRANSMITS_SIGNAL_TO_THE_NUCLEUS Genes involved in Activated NOTCH1 Transmits Signal to the Nucleus