Motif ID: Hmga2

Z-value: 1.183


Transcription factors associated with Hmga2:

Gene SymbolEntrez IDGene Name
Hmga2 ENSMUSG00000056758.8 Hmga2

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Hmga2mm10_v2_chr10_-_120476469_120476527-0.192.6e-01Click!


Activity profile for motif Hmga2.

activity profile for motif Hmga2


Sorted Z-values histogram for motif Hmga2

Sorted Z-values for motif Hmga2



Network of associatons between targets according to the STRING database.



First level regulatory network of Hmga2

PNG image of the network

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Top targets:


Showing 1 to 20 of 139 entries
PromoterScoreRefseqGene SymbolGene Name
chr2_-_98667264 11.578 ENSMUST00000099683.1
 Gm10800
predicted gene 10800
chr9_+_3013140 11.222 ENSMUST00000143083.2
 Gm10721
predicted gene 10721
chr14_-_19418930 10.596 ENSMUST00000177817.1
 Gm21738
predicted gene, 21738
chr9_+_3004457 8.424 ENSMUST00000178348.1
 Gm11168
predicted gene 11168
chr9_+_3023547 7.677 ENSMUST00000099046.3
 Gm10718
predicted gene 10718
chr9_+_3025417 7.175 ENSMUST00000075573.6
 Gm10717
predicted gene 10717
chr9_+_3017408 6.522 ENSMUST00000099049.3
 Gm10719
predicted gene 10719
chr9_+_3018753 6.148 ENSMUST00000179272.1
 Gm10719
predicted gene 10719
chr11_-_102897123 3.644 ENSMUST00000067444.3
 Gfap
glial fibrillary acidic protein
chr11_-_102897146 2.531 ENSMUST00000077902.4
 Gfap
glial fibrillary acidic protein
chr4_-_32923455 2.278 ENSMUST00000035719.4
ENSMUST00000084749.1
 Ankrd6

ankyrin repeat domain 6

chr16_-_43979050 2.192 ENSMUST00000165648.1
ENSMUST00000036321.7
 Zdhhc23

zinc finger, DHHC domain containing 23

chr4_+_44756553 2.159 ENSMUST00000107824.2
 Zcchc7
zinc finger, CCHC domain containing 7
chr13_-_62371936 1.924 ENSMUST00000107989.3
 Gm3604
predicted gene 3604
chr4_+_44756609 1.843 ENSMUST00000143385.1
 Zcchc7
zinc finger, CCHC domain containing 7
chr2_+_62664279 1.769 ENSMUST00000028257.2
 Gca
grancalcin
chr16_-_36784784 1.736 ENSMUST00000165531.1
 Slc15a2
solute carrier family 15 (H+/peptide transporter), member 2
chr13_-_62607499 1.593 ENSMUST00000091563.4
 6720489N17Rik
RIKEN cDNA 6720489N17 gene
chr3_+_88214474 1.424 ENSMUST00000181356.1
ENSMUST00000181396.1
 Gm3764

predicted gene 3764

chr13_-_74482943 1.384 ENSMUST00000074369.6
 Zfp825
zinc finger protein 825

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 57 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.9 6.2 GO:0010624 regulation of Schwann cell proliferation(GO:0010624)
0.6 3.1 GO:0042891 antibiotic transport(GO:0042891) dipeptide transport(GO:0042938)
0.1 2.3 GO:2000096 positive regulation of Wnt signaling pathway, planar cell polarity pathway(GO:2000096)
0.1 2.2 GO:0018345 protein palmitoylation(GO:0018345)
0.4 1.3 GO:0090526 regulation of gluconeogenesis involved in cellular glucose homeostasis(GO:0090526)
0.1 1.3 GO:0000712 resolution of meiotic recombination intermediates(GO:0000712)
0.1 1.1 GO:1901162 serotonin biosynthetic process(GO:0042427) primary amino compound biosynthetic process(GO:1901162)
0.2 1.0 GO:0035521 monoubiquitinated histone deubiquitination(GO:0035521) monoubiquitinated histone H2A deubiquitination(GO:0035522) histone H2A K63-linked deubiquitination(GO:0070537)
0.1 1.0 GO:0035635 entry of bacterium into host cell(GO:0035635) regulation of entry of bacterium into host cell(GO:2000535)
0.1 1.0 GO:0006516 glycoprotein catabolic process(GO:0006516)
0.0 1.0 GO:1900153 regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay(GO:1900151) positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay(GO:1900153)
0.0 1.0 GO:0031100 organ regeneration(GO:0031100)
0.2 0.9 GO:0035609 C-terminal protein deglutamylation(GO:0035609)
0.0 0.9 GO:0043968 histone H2A acetylation(GO:0043968)
0.0 0.9 GO:0001578 microtubule bundle formation(GO:0001578)
0.2 0.8 GO:0072531 pyrimidine-containing compound transmembrane transport(GO:0072531)
0.1 0.8 GO:0036159 inner dynein arm assembly(GO:0036159)
0.1 0.8 GO:0031937 positive regulation of chromatin silencing(GO:0031937)
0.0 0.8 GO:0006120 mitochondrial electron transport, NADH to ubiquinone(GO:0006120)
0.2 0.7 GO:0031554 regulation of DNA-templated transcription, termination(GO:0031554)

Gene overrepresentation in cellular_component category:

Showing 1 to 18 of 18 entries
Log-likelihood per target Total log-likelihoodTermDescription
1.5 6.2 GO:0097450 astrocyte end-foot(GO:0097450)
0.0 1.3 GO:0070469 respiratory chain(GO:0070469)
0.1 1.0 GO:0032584 growth cone membrane(GO:0032584)
0.0 1.0 GO:0035145 exon-exon junction complex(GO:0035145)
0.0 1.0 GO:0010494 cytoplasmic stress granule(GO:0010494)
0.2 0.9 GO:0032777 Piccolo NuA4 histone acetyltransferase complex(GO:0032777)
0.3 0.8 GO:0036156 inner dynein arm(GO:0036156)
0.0 0.7 GO:0030014 CCR4-NOT complex(GO:0030014)
0.0 0.7 GO:0045171 intercellular bridge(GO:0045171)
0.0 0.6 GO:0042588 zymogen granule(GO:0042588)
0.0 0.5 GO:0008074 guanylate cyclase complex, soluble(GO:0008074)
0.0 0.5 GO:0005865 striated muscle thin filament(GO:0005865)
0.1 0.4 GO:0044299 C-fiber(GO:0044299)
0.0 0.4 GO:0005771 multivesicular body(GO:0005771)
0.1 0.3 GO:1990796 photoreceptor cell terminal bouton(GO:1990796)
0.1 0.3 GO:1990415 Pex17p-Pex14p docking complex(GO:1990415) peroxisomal importomer complex(GO:1990429)
0.0 0.2 GO:0031465 Cul4B-RING E3 ubiquitin ligase complex(GO:0031465)
0.0 0.1 GO:0061702 inflammasome complex(GO:0061702)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 35 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 6.1 GO:0005200 structural constituent of cytoskeleton(GO:0005200)
1.0 3.1 GO:0042936 dipeptide transporter activity(GO:0042936)
0.1 2.2 GO:0019707 protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)
0.1 1.7 GO:0004198 calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.1 1.7 GO:0050136 NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.0 1.7 GO:0004004 RNA helicase activity(GO:0003724) ATP-dependent RNA helicase activity(GO:0004004)
0.4 1.1 GO:0004510 tryptophan 5-monooxygenase activity(GO:0004510)
0.0 1.1 GO:0035064 methylated histone binding(GO:0035064)
0.1 1.0 GO:0005537 mannose binding(GO:0005537)
0.0 1.0 GO:0042162 telomeric DNA binding(GO:0042162)
0.0 1.0 GO:0004197 cysteine-type endopeptidase activity(GO:0004197)
0.1 0.9 GO:0004181 metallocarboxypeptidase activity(GO:0004181)
0.1 0.8 GO:0008569 ATP-dependent microtubule motor activity, minus-end-directed(GO:0008569)
0.0 0.8 GO:0015215 nucleotide transmembrane transporter activity(GO:0015215)
0.2 0.7 GO:0001160 transcription termination site sequence-specific DNA binding(GO:0001147) transcription termination site DNA binding(GO:0001160)
0.1 0.7 GO:0001849 complement component C1q binding(GO:0001849)
0.0 0.7 GO:0004535 poly(A)-specific ribonuclease activity(GO:0004535)
0.0 0.7 GO:0019789 SUMO transferase activity(GO:0019789)
0.0 0.7 GO:0032266 phosphatidylinositol-3-phosphate binding(GO:0032266)
0.2 0.6 GO:0071568 UFM1 transferase activity(GO:0071568)

Gene overrepresentation in C2:CP category:

Showing 1 to 7 of 7 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 2.3 ST_WNT_BETA_CATENIN_PATHWAY Wnt/beta-catenin Pathway
0.0 1.6 NABA_ECM_GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.0 1.0 PID_ARF6_TRAFFICKING_PATHWAY Arf6 trafficking events
0.0 0.7 PID_RANBP2_PATHWAY Sumoylation by RanBP2 regulates transcriptional repression
0.0 0.7 PID_IL6_7_PATHWAY IL6-mediated signaling events
0.0 0.5 NABA_COLLAGENS Genes encoding collagen proteins
0.0 0.4 PID_IL23_PATHWAY IL23-mediated signaling events

Gene overrepresentation in C2:CP:REACTOME category:

Showing 1 to 12 of 12 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.2 6.2 REACTOME_NUCLEAR_SIGNALING_BY_ERBB4 Genes involved in Nuclear signaling by ERBB4
0.1 3.1 REACTOME_AMINO_ACID_AND_OLIGOPEPTIDE_SLC_TRANSPORTERS Genes involved in Amino acid and oligopeptide SLC transporters
0.1 1.1 REACTOME_AMINE_DERIVED_HORMONES Genes involved in Amine-derived hormones
0.1 0.7 REACTOME_CREATION_OF_C4_AND_C2_ACTIVATORS Genes involved in Creation of C4 and C2 activators
0.0 0.7 REACTOME_REGULATION_OF_GLUCOKINASE_BY_GLUCOKINASE_REGULATORY_PROTEIN Genes involved in Regulation of Glucokinase by Glucokinase Regulatory Protein
0.0 0.5 REACTOME_NOTCH_HLH_TRANSCRIPTION_PATHWAY Genes involved in Notch-HLH transcription pathway
0.0 0.5 REACTOME_STRIATED_MUSCLE_CONTRACTION Genes involved in Striated Muscle Contraction
0.0 0.5 REACTOME_PHASE1_FUNCTIONALIZATION_OF_COMPOUNDS Genes involved in Phase 1 - Functionalization of compounds
0.0 0.4 REACTOME_AMINE_COMPOUND_SLC_TRANSPORTERS Genes involved in Amine compound SLC transporters
0.0 0.4 REACTOME_HORMONE_SENSITIVE_LIPASE_HSL_MEDIATED_TRIACYLGLYCEROL_HYDROLYSIS Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.0 0.4 REACTOME_ACTIVATION_OF_GENES_BY_ATF4 Genes involved in Activation of Genes by ATF4
0.0 0.3 REACTOME_PROTEOLYTIC_CLEAVAGE_OF_SNARE_COMPLEX_PROTEINS Genes involved in Proteolytic cleavage of SNARE complex proteins