Motif ID: Hmx1

Z-value: 0.649


Transcription factors associated with Hmx1:

Gene SymbolEntrez IDGene Name
Hmx1 ENSMUSG00000067438.3 Hmx1



Activity profile for motif Hmx1.

activity profile for motif Hmx1


Sorted Z-values histogram for motif Hmx1

Sorted Z-values for motif Hmx1



Network of associatons between targets according to the STRING database.



First level regulatory network of Hmx1

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr1_-_172057573 4.726 ENSMUST00000059794.3
Nhlh1
nescient helix loop helix 1
chr6_-_127151044 2.548 ENSMUST00000000188.8
Ccnd2
cyclin D2
chr19_+_25610533 2.100 ENSMUST00000048935.4
Dmrt3
doublesex and mab-3 related transcription factor 3
chr2_+_168081004 2.004 ENSMUST00000052125.6
Pard6b
par-6 (partitioning defective 6) homolog beta (C. elegans)
chr7_-_48881032 1.883 ENSMUST00000058745.8
E2f8
E2F transcription factor 8
chr15_-_32244632 1.739 ENSMUST00000181536.1
0610007N19Rik
RIKEN cDNA 0610007N19
chr9_+_80165079 1.598 ENSMUST00000184480.1
Myo6
myosin VI
chr8_+_45628176 1.492 ENSMUST00000130850.1
Sorbs2
sorbin and SH3 domain containing 2
chr8_+_45627946 1.478 ENSMUST00000145458.1
Sorbs2
sorbin and SH3 domain containing 2
chr7_-_144939823 1.459 ENSMUST00000093962.4
Ccnd1
cyclin D1
chr17_-_33890584 1.406 ENSMUST00000114361.2
ENSMUST00000173492.1
Kifc1

kinesin family member C1

chr6_-_95718800 1.378 ENSMUST00000079847.5
Suclg2
succinate-Coenzyme A ligase, GDP-forming, beta subunit
chr17_-_33890539 1.366 ENSMUST00000173386.1
Kifc1
kinesin family member C1
chr5_-_98030727 1.363 ENSMUST00000031281.9
Antxr2
anthrax toxin receptor 2
chr10_-_80261004 1.353 ENSMUST00000105363.1
Gamt
guanidinoacetate methyltransferase
chr1_+_135729147 1.346 ENSMUST00000027677.7
Csrp1
cysteine and glycine-rich protein 1
chr10_-_80260959 1.332 ENSMUST00000020359.6
Gamt
guanidinoacetate methyltransferase
chr15_+_32244801 1.242 ENSMUST00000067458.6
Sema5a
sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A
chr10_+_93641041 1.236 ENSMUST00000020204.4
Ntn4
netrin 4
chr15_+_55307743 1.234 ENSMUST00000023053.5
ENSMUST00000110221.2
ENSMUST00000110217.3
Col14a1


collagen, type XIV, alpha 1


chr12_+_109459843 1.216 ENSMUST00000173812.1
Dlk1
delta-like 1 homolog (Drosophila)
chr4_+_94556546 1.155 ENSMUST00000094969.1
Gm10306
predicted gene 10306
chr2_+_92915080 1.151 ENSMUST00000028648.2
Syt13
synaptotagmin XIII
chr2_+_164562579 1.145 ENSMUST00000017867.3
ENSMUST00000109344.2
ENSMUST00000109345.2
Wfdc2


WAP four-disulfide core domain 2


chr1_+_109983006 1.094 ENSMUST00000145188.1
Cdh7
cadherin 7, type 2
chr4_+_116221689 1.093 ENSMUST00000106490.2
Pik3r3
phosphatidylinositol 3 kinase, regulatory subunit, polypeptide 3 (p55)
chr11_+_61956779 1.074 ENSMUST00000049836.7
Specc1
sperm antigen with calponin homology and coiled-coil domains 1
chr3_+_131112785 1.033 ENSMUST00000098611.3
Lef1
lymphoid enhancer binding factor 1
chr8_+_45627709 1.026 ENSMUST00000134321.1
ENSMUST00000135336.1
Sorbs2

sorbin and SH3 domain containing 2

chr15_-_85578070 0.983 ENSMUST00000109424.2
Wnt7b
wingless-related MMTV integration site 7B
chr5_+_114568016 0.957 ENSMUST00000043650.7
Fam222a
family with sequence similarity 222, member A
chr4_+_116221590 0.941 ENSMUST00000147292.1
Pik3r3
phosphatidylinositol 3 kinase, regulatory subunit, polypeptide 3 (p55)
chr13_-_29984219 0.938 ENSMUST00000146092.1
E2f3
E2F transcription factor 3
chr4_-_91371946 0.936 ENSMUST00000176362.1
Elavl2
ELAV (embryonic lethal, abnormal vision, Drosophila)-like 2 (Hu antigen B)
chr5_-_39644634 0.922 ENSMUST00000053116.6
Hs3st1
heparan sulfate (glucosamine) 3-O-sulfotransferase 1
chr1_-_9700209 0.915 ENSMUST00000088658.4
Mybl1
myeloblastosis oncogene-like 1
chr17_-_12769605 0.897 ENSMUST00000024599.7
Igf2r
insulin-like growth factor 2 receptor
chr5_-_39644597 0.893 ENSMUST00000152057.1
Hs3st1
heparan sulfate (glucosamine) 3-O-sulfotransferase 1
chr2_-_30474199 0.879 ENSMUST00000065134.2
Ier5l
immediate early response 5-like
chr15_-_13173607 0.868 ENSMUST00000036439.4
Cdh6
cadherin 6
chr7_+_29071597 0.867 ENSMUST00000180926.1
Gm26604
predicted gene, 26604
chr8_-_4217133 0.862 ENSMUST00000175906.1
BC068157
cDNA sequence BC068157
chr2_+_165595009 0.861 ENSMUST00000088132.6
Eya2
eyes absent 2 homolog (Drosophila)
chr14_+_103070216 0.852 ENSMUST00000022721.6
Cln5
ceroid-lipofuscinosis, neuronal 5
chr17_+_26917091 0.844 ENSMUST00000078961.4
Kifc5b
kinesin family member C5B
chr14_+_7817957 0.835 ENSMUST00000052678.8
Flnb
filamin, beta
chr8_+_120537423 0.827 ENSMUST00000118136.1
Gse1
genetic suppressor element 1
chr8_-_4217459 0.805 ENSMUST00000176227.1
BC068157
cDNA sequence BC068157
chr7_-_80232752 0.783 ENSMUST00000065163.8
Cib1
calcium and integrin binding 1 (calmyrin)
chr4_+_116221633 0.773 ENSMUST00000030464.7
Pik3r3
phosphatidylinositol 3 kinase, regulatory subunit, polypeptide 3 (p55)
chr7_+_80232862 0.769 ENSMUST00000062915.7
Gdpgp1
GDP-D-glucose phosphorylase 1
chr5_+_121220191 0.768 ENSMUST00000119892.2
ENSMUST00000042614.6
Gm15800

predicted gene 15800

chr1_+_109982710 0.760 ENSMUST00000112701.1
Cdh7
cadherin 7, type 2
chr6_+_30738044 0.753 ENSMUST00000128398.1
ENSMUST00000163949.2
ENSMUST00000124665.1
Mest


mesoderm specific transcript


chr6_-_127109517 0.728 ENSMUST00000039913.8
9630033F20Rik
RIKEN cDNA 9630033F20 gene
chr9_-_42124276 0.717 ENSMUST00000060989.8
Sorl1
sortilin-related receptor, LDLR class A repeats-containing
chr9_+_62838767 0.699 ENSMUST00000034776.6
Cln6
ceroid-lipofuscinosis, neuronal 6
chr17_+_34592248 0.699 ENSMUST00000038149.6
Pbx2
pre B cell leukemia homeobox 2
chr11_+_3289880 0.698 ENSMUST00000110043.1
ENSMUST00000094471.3
Patz1

POZ (BTB) and AT hook containing zinc finger 1

chr11_-_94242701 0.670 ENSMUST00000061469.3
Wfikkn2
WAP, follistatin/kazal, immunoglobulin, kunitz and netrin domain containing 2
chr8_+_83389878 0.668 ENSMUST00000109831.2
Clgn
calmegin
chr17_+_31057686 0.664 ENSMUST00000024829.6
Abcg1
ATP-binding cassette, sub-family G (WHITE), member 1
chr17_+_86963279 0.663 ENSMUST00000139344.1
Rhoq
ras homolog gene family, member Q
chr7_-_101921186 0.624 ENSMUST00000106965.1
ENSMUST00000106968.1
ENSMUST00000106967.1
Lrrc51


leucine rich repeat containing 51


chr5_+_115429944 0.592 ENSMUST00000067168.5
Msi1
musashi RNA-binding protein 1
chr12_+_110279228 0.592 ENSMUST00000097228.4
Dio3
deiodinase, iodothyronine type III
chr4_-_94556737 0.584 ENSMUST00000030313.8
Caap1
caspase activity and apoptosis inhibitor 1
chr9_+_46012822 0.574 ENSMUST00000120463.2
ENSMUST00000120247.1
Sik3

SIK family kinase 3

chr8_-_4216912 0.571 ENSMUST00000177491.1
BC068157
cDNA sequence BC068157
chr11_-_119547744 0.569 ENSMUST00000026670.4
Nptx1
neuronal pentraxin 1
chr2_+_129198757 0.568 ENSMUST00000028880.3
Slc20a1
solute carrier family 20, member 1
chr7_+_19083842 0.565 ENSMUST00000032568.7
ENSMUST00000122999.1
ENSMUST00000108473.3
ENSMUST00000108474.1
Dmpk



dystrophia myotonica-protein kinase



chr11_+_120491840 0.546 ENSMUST00000026899.3
Slc25a10
solute carrier family 25 (mitochondrial carrier, dicarboxylate transporter), member 10
chr1_+_34005872 0.541 ENSMUST00000182296.1
Dst
dystonin
chr8_-_4217261 0.539 ENSMUST00000168386.2
BC068157
cDNA sequence BC068157
chr18_+_65581704 0.539 ENSMUST00000182979.1
Zfp532
zinc finger protein 532
chr10_+_80265035 0.536 ENSMUST00000092305.5
Dazap1
DAZ associated protein 1
chr15_+_81586206 0.532 ENSMUST00000068387.4
Ep300
E1A binding protein p300
chr11_+_3290300 0.528 ENSMUST00000057089.6
ENSMUST00000093402.5
Patz1

POZ (BTB) and AT hook containing zinc finger 1

chr2_-_160872829 0.527 ENSMUST00000176141.1
Zhx3
zinc fingers and homeoboxes 3
chr6_+_34476207 0.525 ENSMUST00000045372.5
ENSMUST00000138668.1
ENSMUST00000139067.1
Bpgm


2,3-bisphosphoglycerate mutase


chrX_-_100626568 0.521 ENSMUST00000015812.5
Pdzd11
PDZ domain containing 11
chr2_-_38287174 0.514 ENSMUST00000130472.1
Dennd1a
DENN/MADD domain containing 1A
chrX_-_102644210 0.511 ENSMUST00000052012.7
ENSMUST00000043596.5
ENSMUST00000119229.1
ENSMUST00000122022.1
ENSMUST00000120270.1
ENSMUST00000113611.2
Phka1





phosphorylase kinase alpha 1





chr3_+_86224665 0.506 ENSMUST00000107635.1
Lrba
LPS-responsive beige-like anchor
chr8_+_83389846 0.482 ENSMUST00000002259.6
Clgn
calmegin
chr11_+_69965396 0.481 ENSMUST00000018713.6
Cldn7
claudin 7
chr17_-_10319324 0.481 ENSMUST00000097414.3
ENSMUST00000042296.7
Qk

quaking

chr15_-_59374149 0.479 ENSMUST00000022976.4
E430025E21Rik
RIKEN cDNA E430025E21 gene
chr7_-_126160992 0.478 ENSMUST00000164741.1
Xpo6
exportin 6
chr10_+_80264942 0.473 ENSMUST00000105362.1
ENSMUST00000105361.3
Dazap1

DAZ associated protein 1

chr11_+_68692070 0.471 ENSMUST00000108673.1
Myh10
myosin, heavy polypeptide 10, non-muscle
chr7_+_118712516 0.461 ENSMUST00000106557.1
Ccp110
centriolar coiled coil protein 110
chrX_+_10717451 0.457 ENSMUST00000156321.1
Mid1ip1
Mid1 interacting protein 1 (gastrulation specific G12-like (zebrafish))
chr3_+_108284089 0.457 ENSMUST00000102632.4
Sort1
sortilin 1
chrX_+_50841434 0.453 ENSMUST00000114887.2
2610018G03Rik
RIKEN cDNA 2610018G03 gene
chr14_+_73173825 0.449 ENSMUST00000166875.1
Rcbtb2
regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 2
chr8_-_25016901 0.447 ENSMUST00000084035.5
Adam9
a disintegrin and metallopeptidase domain 9 (meltrin gamma)
chr9_+_46012810 0.440 ENSMUST00000126865.1
Sik3
SIK family kinase 3
chr12_+_112620030 0.439 ENSMUST00000180015.1
ENSMUST00000021726.6
Adssl1

adenylosuccinate synthetase like 1

chr6_+_58831456 0.421 ENSMUST00000141600.1
ENSMUST00000122981.1
Herc3

hect domain and RLD 3

chr14_-_52237572 0.418 ENSMUST00000089752.4
Chd8
chromodomain helicase DNA binding protein 8
chrX_+_10717390 0.417 ENSMUST00000115524.1
ENSMUST00000008179.6
Mid1ip1

Mid1 interacting protein 1 (gastrulation specific G12-like (zebrafish))

chr19_+_6046576 0.411 ENSMUST00000138532.1
ENSMUST00000129081.1
ENSMUST00000156550.1
Syvn1


synovial apoptosis inhibitor 1, synoviolin


chr9_-_99140065 0.408 ENSMUST00000035037.7
Pik3cb
phosphatidylinositol 3-kinase, catalytic, beta polypeptide
chrX_+_159255919 0.401 ENSMUST00000112492.1
Rps6ka3
ribosomal protein S6 kinase polypeptide 3
chr9_+_95954744 0.398 ENSMUST00000034981.7
Xrn1
5'-3' exoribonuclease 1
chr16_-_96082389 0.397 ENSMUST00000099502.2
ENSMUST00000023631.8
ENSMUST00000113829.1
ENSMUST00000153398.1
Brwd1



bromodomain and WD repeat domain containing 1



chr2_+_174327747 0.395 ENSMUST00000087871.4
Gnas
GNAS (guanine nucleotide binding protein, alpha stimulating) complex locus
chr9_-_119825456 0.381 ENSMUST00000070617.7
Scn11a
sodium channel, voltage-gated, type XI, alpha
chr11_-_46312220 0.371 ENSMUST00000129474.1
ENSMUST00000093166.4
ENSMUST00000165599.2
Cyfip2


cytoplasmic FMR1 interacting protein 2


chr7_-_79715669 0.368 ENSMUST00000184137.1
ENSMUST00000183846.1
Kif7

kinesin family member 7

chr4_-_108071327 0.367 ENSMUST00000106701.1
Scp2
sterol carrier protein 2, liver
chr16_+_10545390 0.365 ENSMUST00000115827.1
ENSMUST00000038145.6
ENSMUST00000150894.1
Clec16a


C-type lectin domain family 16, member A


chr4_+_156013835 0.365 ENSMUST00000030952.5
Tnfrsf4
tumor necrosis factor receptor superfamily, member 4
chr10_-_30618337 0.362 ENSMUST00000019925.5
Hint3
histidine triad nucleotide binding protein 3
chr1_-_143702832 0.360 ENSMUST00000018337.7
Cdc73
cell division cycle 73, Paf1/RNA polymerase II complex component
chr8_-_25016743 0.357 ENSMUST00000084032.5
Adam9
a disintegrin and metallopeptidase domain 9 (meltrin gamma)
chr14_-_52237791 0.356 ENSMUST00000149975.1
Chd8
chromodomain helicase DNA binding protein 8
chr5_-_31291026 0.352 ENSMUST00000041565.7
Ift172
intraflagellar transport 172
chr11_-_116843449 0.345 ENSMUST00000047616.3
Jmjd6
jumonji domain containing 6
chr15_+_103503261 0.337 ENSMUST00000023132.3
Pde1b
phosphodiesterase 1B, Ca2+-calmodulin dependent
chr14_-_54686926 0.336 ENSMUST00000022793.8
ENSMUST00000111484.2
Acin1

apoptotic chromatin condensation inducer 1

chr16_-_96082513 0.335 ENSMUST00000113827.1
Brwd1
bromodomain and WD repeat domain containing 1
chr10_-_76961788 0.333 ENSMUST00000001148.4
ENSMUST00000105411.2
Pcbp3

poly(rC) binding protein 3

chr10_-_77113928 0.329 ENSMUST00000149744.1
Col18a1
collagen, type XVIII, alpha 1
chr6_+_8948608 0.325 ENSMUST00000160300.1
Nxph1
neurexophilin 1
chr5_-_134614953 0.325 ENSMUST00000036362.6
ENSMUST00000077636.4
Lat2

linker for activation of T cells family, member 2

chr2_-_73453918 0.322 ENSMUST00000102679.1
Wipf1
WAS/WASL interacting protein family, member 1
chr17_-_23684019 0.321 ENSMUST00000085989.5
Cldn9
claudin 9
chr2_+_30237680 0.313 ENSMUST00000113654.1
ENSMUST00000095078.2
Lrrc8a

leucine rich repeat containing 8A

chr15_-_79687776 0.304 ENSMUST00000023061.5
Josd1
Josephin domain containing 1
chr11_+_98927785 0.300 ENSMUST00000107474.1
Rara
retinoic acid receptor, alpha
chr8_+_105297663 0.300 ENSMUST00000015003.8
E2f4
E2F transcription factor 4
chr4_+_141115660 0.297 ENSMUST00000181450.1
4921514A10Rik
RIKEN cDNA 4921514A10 gene
chr15_+_41788979 0.296 ENSMUST00000170127.1
Oxr1
oxidation resistance 1
chr11_-_115367667 0.284 ENSMUST00000123428.1
ENSMUST00000044152.6
ENSMUST00000106542.2
Hid1


HID1 domain containing


chrX_-_74246364 0.282 ENSMUST00000130007.1
Flna
filamin, alpha
chr14_+_64652524 0.280 ENSMUST00000100473.4
Kif13b
kinesin family member 13B
chr15_+_8109313 0.280 ENSMUST00000163765.1
Nup155
nucleoporin 155
chr10_-_77113676 0.278 ENSMUST00000072755.4
ENSMUST00000105409.1
Col18a1

collagen, type XVIII, alpha 1

chr2_-_38287347 0.274 ENSMUST00000102787.3
Dennd1a
DENN/MADD domain containing 1A
chr11_+_62820469 0.273 ENSMUST00000108703.1
Trim16
tripartite motif-containing 16
chr11_-_120624973 0.272 ENSMUST00000106183.2
ENSMUST00000080202.5
Sirt7

sirtuin 7

chr13_+_20090538 0.264 ENSMUST00000072519.5
Elmo1
engulfment and cell motility 1
chr14_+_54640952 0.263 ENSMUST00000169818.2
Gm17606
predicted gene, 17606
chr16_+_17619503 0.263 ENSMUST00000165092.1
Smpd4
sphingomyelin phosphodiesterase 4
chr7_+_141949982 0.262 ENSMUST00000105989.2
ENSMUST00000075528.5
ENSMUST00000174499.1
Brsk2


BR serine/threonine kinase 2


chr2_+_118926496 0.259 ENSMUST00000099546.4
ENSMUST00000110837.1
Chst14

carbohydrate (N-acetylgalactosamine 4-0) sulfotransferase 14

chr17_-_45686120 0.257 ENSMUST00000143907.1
ENSMUST00000127065.1
Tmem63b

transmembrane protein 63b

chr2_-_92370999 0.255 ENSMUST00000176810.1
ENSMUST00000090582.4
Gyltl1b

glycosyltransferase-like 1B

chr3_-_89418287 0.254 ENSMUST00000029679.3
Cks1b
CDC28 protein kinase 1b
chr5_-_31154152 0.253 ENSMUST00000114632.1
ENSMUST00000114631.2
ENSMUST00000067186.6
ENSMUST00000137165.1
ENSMUST00000131391.1
ENSMUST00000141823.1
ENSMUST00000154241.1
Mpv17






MpV17 mitochondrial inner membrane protein






chr9_-_110654161 0.253 ENSMUST00000133191.1
ENSMUST00000167320.1
Nbeal2

neurobeachin-like 2

chr2_-_92371039 0.249 ENSMUST00000068586.6
Gyltl1b
glycosyltransferase-like 1B
chr1_-_39577340 0.247 ENSMUST00000062525.5
Rnf149
ring finger protein 149
chr14_-_54686605 0.244 ENSMUST00000147714.1
Acin1
apoptotic chromatin condensation inducer 1
chr16_-_18089022 0.243 ENSMUST00000132241.1
ENSMUST00000139861.1
ENSMUST00000003620.5
Prodh


proline dehydrogenase


chr8_+_4240105 0.242 ENSMUST00000110994.1
ENSMUST00000110995.1
Map2k7

mitogen-activated protein kinase kinase 7

chr13_-_46929718 0.240 ENSMUST00000056978.7
Kif13a
kinesin family member 13A
chrX_-_74393103 0.239 ENSMUST00000114142.1
ENSMUST00000114139.1
ENSMUST00000114141.1
Fam3a


family with sequence similarity 3, member A


chr10_-_116950366 0.238 ENSMUST00000020375.6
Rab3ip
RAB3A interacting protein
chr15_-_79834261 0.234 ENSMUST00000148358.1
Cbx6
chromobox 6
chr5_+_28165690 0.232 ENSMUST00000036177.7
En2
engrailed 2
chr1_-_156718989 0.231 ENSMUST00000122424.1
Fam20b
family with sequence similarity 20, member B
chr9_+_62341329 0.231 ENSMUST00000085519.6
Anp32a
acidic (leucine-rich) nuclear phosphoprotein 32 family, member A
chr3_+_103058302 0.230 ENSMUST00000029445.6
Nras
neuroblastoma ras oncogene
chr12_+_24572276 0.229 ENSMUST00000085553.5
Grhl1
grainyhead-like 1 (Drosophila)
chrX_-_134808984 0.226 ENSMUST00000035559.4
Armcx2
armadillo repeat containing, X-linked 2
chr1_-_156718894 0.218 ENSMUST00000086153.6
Fam20b
family with sequence similarity 20, member B
chr19_-_4615453 0.214 ENSMUST00000053597.2
Lrfn4
leucine rich repeat and fibronectin type III domain containing 4
chr15_+_88819584 0.209 ENSMUST00000024042.3
Creld2
cysteine-rich with EGF-like domains 2
chr11_-_69858723 0.209 ENSMUST00000001626.3
ENSMUST00000108626.1
Tnk1

tyrosine kinase, non-receptor, 1

chrX_-_74246534 0.208 ENSMUST00000101454.2
ENSMUST00000033699.6
Flna

filamin, alpha

chr13_+_20090500 0.208 ENSMUST00000165249.2
Elmo1
engulfment and cell motility 1
chr9_-_20976762 0.206 ENSMUST00000054197.5
S1pr2
sphingosine-1-phosphate receptor 2
chr7_-_101921175 0.205 ENSMUST00000098236.2
Lrrc51
leucine rich repeat containing 51
chr14_+_54883377 0.203 ENSMUST00000022806.3
ENSMUST00000172844.1
ENSMUST00000133397.2
ENSMUST00000134077.1
Bcl2l2


Gm20521
BCL2-like 2


predicted gene 20521
chr17_+_25786566 0.202 ENSMUST00000095500.4
Ccdc78
coiled-coil domain containing 78
chr2_+_3704787 0.201 ENSMUST00000115054.2
Fam107b
family with sequence similarity 107, member B
chr19_-_4615647 0.193 ENSMUST00000113822.2
Lrfn4
leucine rich repeat and fibronectin type III domain containing 4
chr2_-_130629994 0.188 ENSMUST00000028761.4
ENSMUST00000110262.1
Ubox5
Fastkd5
U box domain containing 5
FAST kinase domains 5
chr12_-_108179210 0.188 ENSMUST00000125916.2
ENSMUST00000109879.1
Setd3

SET domain containing 3

chr6_-_91116785 0.186 ENSMUST00000113509.1
ENSMUST00000032179.7
Nup210

nucleoporin 210

chr2_+_28513243 0.182 ENSMUST00000028170.8
Ralgds
ral guanine nucleotide dissociation stimulator
chr15_-_74709535 0.179 ENSMUST00000050234.2
Jrk
jerky
chr11_+_88973928 0.175 ENSMUST00000036649.4
ENSMUST00000107898.3
Coil

coilin

chr11_-_101425330 0.175 ENSMUST00000103102.3
Ptges3l
prostaglandin E synthase 3 (cytosolic)-like
chr16_+_17619341 0.173 ENSMUST00000006053.6
ENSMUST00000171435.1
ENSMUST00000163476.1
ENSMUST00000168101.1
ENSMUST00000165363.1
ENSMUST00000169662.1
ENSMUST00000090159.4
ENSMUST00000172182.1
ENSMUST00000163592.1
Smpd4








sphingomyelin phosphodiesterase 4








chr9_+_90162978 0.167 ENSMUST00000113060.1
Adamts7
a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 7
chr10_-_30618436 0.166 ENSMUST00000161074.1
Hint3
histidine triad nucleotide binding protein 3
chr11_+_68692097 0.165 ENSMUST00000018887.8
Myh10
myosin, heavy polypeptide 10, non-muscle
chr4_+_109676568 0.165 ENSMUST00000102724.4
Faf1
Fas-associated factor 1
chr11_-_101424519 0.163 ENSMUST00000107257.1
ENSMUST00000107259.3
ENSMUST00000107252.2
ENSMUST00000093933.4
Gm27029

Ptges3l

predicted gene, 27029

prostaglandin E synthase 3 (cytosolic)-like

chr5_-_33274966 0.160 ENSMUST00000079746.6
Ctbp1
C-terminal binding protein 1
chrX_-_74023745 0.159 ENSMUST00000114353.3
ENSMUST00000101458.2
Irak1

interleukin-1 receptor-associated kinase 1

chr17_-_45685973 0.158 ENSMUST00000145873.1
Tmem63b
transmembrane protein 63b
chr9_+_90163057 0.156 ENSMUST00000113059.1
ENSMUST00000167122.1
Adamts7

a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 7

chr1_-_37430071 0.144 ENSMUST00000027286.6
Coa5
cytochrome C oxidase assembly factor 5
chr2_+_28513105 0.140 ENSMUST00000135803.1
Ralgds
ral guanine nucleotide dissociation stimulator

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.9 2.8 GO:0072382 minus-end-directed vesicle transport along microtubule(GO:0072382)
0.9 2.7 GO:0006601 creatine biosynthetic process(GO:0006601)
0.6 1.9 GO:0032877 positive regulation of DNA endoreduplication(GO:0032877)
0.3 1.0 GO:0032696 negative regulation of interleukin-13 production(GO:0032696) trachea submucosa development(GO:0061152) trachea gland development(GO:0061153) odontoblast differentiation(GO:0071895) regulation of estrogen receptor binding(GO:0071898) negative regulation of estrogen receptor binding(GO:0071899)
0.3 1.0 GO:0016332 establishment or maintenance of polarity of embryonic epithelium(GO:0016332)
0.3 0.8 GO:0034241 positive regulation of macrophage fusion(GO:0034241)
0.2 1.2 GO:0035426 extracellular matrix-cell signaling(GO:0035426)
0.2 0.7 GO:0070650 actin filament bundle distribution(GO:0070650)
0.2 1.5 GO:0000320 re-entry into mitotic cell cycle(GO:0000320)
0.2 2.5 GO:0071481 cellular response to X-ray(GO:0071481)
0.2 0.8 GO:2000256 endomitotic cell cycle(GO:0007113) thrombopoietin-mediated signaling pathway(GO:0038163) positive regulation of male germ cell proliferation(GO:2000256)
0.2 2.1 GO:0042487 regulation of odontogenesis of dentin-containing tooth(GO:0042487)
0.2 0.7 GO:2001137 positive regulation of ER to Golgi vesicle-mediated transport(GO:1902953) positive regulation of endocytic recycling(GO:2001137)
0.2 0.5 GO:0014735 positive regulation of transcription from RNA polymerase II promoter involved in unfolded protein response(GO:0006990) regulation of muscle atrophy(GO:0014735)
0.2 0.5 GO:0043456 regulation of pentose-phosphate shunt(GO:0043456)
0.2 0.9 GO:1904426 positive regulation of GTP binding(GO:1904426)
0.2 0.7 GO:0055099 response to high density lipoprotein particle(GO:0055099)
0.2 0.5 GO:1905000 regulation of membrane repolarization during atrial cardiac muscle cell action potential(GO:1905000)
0.2 0.9 GO:0070345 negative regulation of fat cell proliferation(GO:0070345)
0.2 1.2 GO:0030836 positive regulation of actin filament depolymerization(GO:0030836) positive regulation of axon extension involved in axon guidance(GO:0048842) positive regulation of extracellular matrix disassembly(GO:0090091)
0.2 1.4 GO:0006104 succinyl-CoA metabolic process(GO:0006104)
0.1 0.4 GO:0044208 'de novo' AMP biosynthetic process(GO:0044208)
0.1 0.6 GO:0014722 regulation of skeletal muscle contraction by calcium ion signaling(GO:0014722)
0.1 0.5 GO:0015744 succinate transport(GO:0015744)
0.1 0.8 GO:0032483 regulation of Rab protein signal transduction(GO:0032483)
0.1 0.1 GO:2000040 regulation of planar cell polarity pathway involved in axis elongation(GO:2000040) negative regulation of planar cell polarity pathway involved in axis elongation(GO:2000041)
0.1 0.3 GO:1905034 regulation of antifungal innate immune response(GO:1905034) negative regulation of antifungal innate immune response(GO:1905035)
0.1 0.5 GO:0032053 ciliary basal body organization(GO:0032053)
0.1 1.6 GO:0071257 cellular response to electrical stimulus(GO:0071257)
0.1 0.6 GO:0035864 response to potassium ion(GO:0035864) cellular response to potassium ion(GO:0035865) axonogenesis involved in innervation(GO:0060385)
0.1 0.9 GO:0016576 histone dephosphorylation(GO:0016576)
0.1 0.5 GO:1903361 protein localization to basolateral plasma membrane(GO:1903361)
0.1 0.3 GO:0060010 Sertoli cell fate commitment(GO:0060010)
0.1 4.4 GO:0003301 physiological muscle hypertrophy(GO:0003298) physiological cardiac muscle hypertrophy(GO:0003301) cell growth involved in cardiac muscle cell development(GO:0061049)
0.1 0.5 GO:1901097 negative regulation of autophagosome maturation(GO:1901097)
0.1 0.3 GO:0036228 protein targeting to nuclear inner membrane(GO:0036228)
0.1 0.4 GO:0032382 positive regulation of intracellular lipid transport(GO:0032379) positive regulation of intracellular sterol transport(GO:0032382) positive regulation of intracellular cholesterol transport(GO:0032385) lipid hydroperoxide transport(GO:1901373)
0.1 0.3 GO:0030208 dermatan sulfate biosynthetic process(GO:0030208)
0.1 0.6 GO:0046549 phenol-containing compound catabolic process(GO:0019336) retinal cone cell development(GO:0046549)
0.1 0.3 GO:0070889 platelet alpha granule organization(GO:0070889)
0.1 0.6 GO:0030263 apoptotic chromosome condensation(GO:0030263)
0.1 0.4 GO:0040032 post-embryonic body morphogenesis(GO:0040032)
0.1 0.3 GO:0002329 pre-B cell differentiation(GO:0002329)
0.1 0.8 GO:2000270 negative regulation of fibroblast apoptotic process(GO:2000270)
0.1 0.4 GO:0033031 positive regulation of neutrophil apoptotic process(GO:0033031)
0.1 0.3 GO:0045896 regulation of transcription during mitosis(GO:0045896) positive regulation of transcription during mitosis(GO:0045897)
0.1 0.3 GO:0036006 response to macrophage colony-stimulating factor(GO:0036005) cellular response to macrophage colony-stimulating factor stimulus(GO:0036006)
0.1 2.6 GO:0043551 regulation of phosphatidylinositol 3-kinase activity(GO:0043551)
0.1 0.5 GO:0051004 plasma membrane to endosome transport(GO:0048227) regulation of lipoprotein lipase activity(GO:0051004)
0.1 0.7 GO:0007042 lysosomal lumen acidification(GO:0007042)
0.1 0.4 GO:0006685 sphingomyelin catabolic process(GO:0006685)
0.1 0.9 GO:0045723 positive regulation of fatty acid biosynthetic process(GO:0045723)
0.1 0.3 GO:0043654 peptidyl-lysine hydroxylation(GO:0017185) recognition of apoptotic cell(GO:0043654)
0.1 0.2 GO:0098928 presynaptic signal transduction(GO:0098928) presynapse to nucleus signaling pathway(GO:0099526)
0.1 0.4 GO:0051388 positive regulation of neurotrophin TRK receptor signaling pathway(GO:0051388)
0.1 1.2 GO:0045780 positive regulation of bone resorption(GO:0045780) positive regulation of bone remodeling(GO:0046852)
0.1 1.2 GO:0035036 binding of sperm to zona pellucida(GO:0007339) sperm-egg recognition(GO:0035036)
0.0 0.8 GO:0003334 keratinocyte development(GO:0003334)
0.0 0.2 GO:0072383 plus-end-directed vesicle transport along microtubule(GO:0072383) plus-end-directed organelle transport along microtubule(GO:0072386)
0.0 0.4 GO:0051024 positive regulation of immunoglobulin secretion(GO:0051024)
0.0 0.2 GO:0006421 asparaginyl-tRNA aminoacylation(GO:0006421)
0.0 0.2 GO:0003376 sphingosine-1-phosphate signaling pathway(GO:0003376) sphingolipid mediated signaling pathway(GO:0090520)
0.0 0.2 GO:0090370 negative regulation of cholesterol efflux(GO:0090370)
0.0 1.0 GO:0048026 positive regulation of mRNA splicing, via spliceosome(GO:0048026)
0.0 0.2 GO:0002934 desmosome organization(GO:0002934)
0.0 0.6 GO:0006817 phosphate ion transport(GO:0006817)
0.0 0.8 GO:0010883 regulation of lipid storage(GO:0010883)
0.0 0.5 GO:0061158 3'-UTR-mediated mRNA destabilization(GO:0061158)
0.0 0.4 GO:0090503 histone mRNA catabolic process(GO:0071044) RNA phosphodiester bond hydrolysis, exonucleolytic(GO:0090503)
0.0 1.4 GO:1901998 toxin transport(GO:1901998)
0.0 0.1 GO:1902514 regulation of calcium ion transmembrane transport via high voltage-gated calcium channel(GO:1902514)
0.0 0.2 GO:0060011 Sertoli cell proliferation(GO:0060011)
0.0 0.6 GO:0001886 endothelial cell morphogenesis(GO:0001886)
0.0 0.2 GO:0007253 cytoplasmic sequestering of NF-kappaB(GO:0007253)
0.0 1.2 GO:0048791 calcium ion-regulated exocytosis of neurotransmitter(GO:0048791)
0.0 0.5 GO:0008090 retrograde axonal transport(GO:0008090)
0.0 0.3 GO:1902083 negative regulation of peptidyl-cysteine S-nitrosylation(GO:1902083)
0.0 1.0 GO:0060351 cartilage development involved in endochondral bone morphogenesis(GO:0060351)
0.0 0.2 GO:0098535 de novo centriole assembly(GO:0098535)
0.0 1.3 GO:0070527 platelet aggregation(GO:0070527)
0.0 0.5 GO:0032460 negative regulation of protein oligomerization(GO:0032460) negative regulation of protein homooligomerization(GO:0032463)
0.0 0.3 GO:0032836 glomerular basement membrane development(GO:0032836)
0.0 0.1 GO:0007352 zygotic specification of dorsal/ventral axis(GO:0007352) positive regulation of nodal signaling pathway involved in determination of lateral mesoderm left/right asymmetry(GO:1900224) positive regulation of mesoderm development(GO:2000382)
0.0 0.7 GO:0030866 cortical actin cytoskeleton organization(GO:0030866)
0.0 0.3 GO:0048386 positive regulation of retinoic acid receptor signaling pathway(GO:0048386)
0.0 0.4 GO:0000083 regulation of transcription involved in G1/S transition of mitotic cell cycle(GO:0000083)
0.0 0.2 GO:0006560 proline metabolic process(GO:0006560)
0.0 0.2 GO:2000671 regulation of motor neuron apoptotic process(GO:2000671)
0.0 0.1 GO:1990839 response to endothelin(GO:1990839)
0.0 0.4 GO:0033523 endodermal cell fate commitment(GO:0001711) histone H2B ubiquitination(GO:0033523)
0.0 0.1 GO:0023041 neuronal signal transduction(GO:0023041)
0.0 0.2 GO:0090394 negative regulation of excitatory postsynaptic potential(GO:0090394)
0.0 0.4 GO:0070986 left/right axis specification(GO:0070986)
0.0 0.1 GO:0006452 translational frameshifting(GO:0006452) positive regulation of translational termination(GO:0045905)
0.0 1.5 GO:0007043 cell-cell junction assembly(GO:0007043)
0.0 0.1 GO:0032439 endosome localization(GO:0032439)
0.0 0.2 GO:0072600 establishment of protein localization to Golgi(GO:0072600)
0.0 0.1 GO:1902525 regulation of protein monoubiquitination(GO:1902525)
0.0 0.2 GO:0000963 mitochondrial RNA processing(GO:0000963)
0.0 0.2 GO:1990403 embryonic brain development(GO:1990403)
0.0 0.4 GO:1902236 negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway(GO:1902236)
0.0 0.3 GO:0050853 B cell receptor signaling pathway(GO:0050853)
0.0 0.7 GO:0043392 negative regulation of DNA binding(GO:0043392)
0.0 0.4 GO:0045879 negative regulation of smoothened signaling pathway(GO:0045879)
0.0 1.2 GO:0008584 male gonad development(GO:0008584) development of primary male sexual characteristics(GO:0046546)
0.0 0.3 GO:0046827 positive regulation of protein export from nucleus(GO:0046827)
0.0 0.0 GO:0048711 positive regulation of astrocyte differentiation(GO:0048711)
0.0 0.5 GO:0045669 positive regulation of osteoblast differentiation(GO:0045669)
0.0 0.5 GO:0006611 protein export from nucleus(GO:0006611)
0.0 0.8 GO:0032526 response to retinoic acid(GO:0032526)
0.0 0.2 GO:0046580 negative regulation of Ras protein signal transduction(GO:0046580) negative regulation of small GTPase mediated signal transduction(GO:0051058)
0.0 0.5 GO:0006911 phagocytosis, engulfment(GO:0006911)
0.0 0.1 GO:0021854 hypothalamus development(GO:0021854)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 2.5 GO:0097129 cyclin D2-CDK4 complex(GO:0097129)
0.2 1.4 GO:0030062 mitochondrial tricarboxylic acid cycle enzyme complex(GO:0030062)
0.1 3.2 GO:0005942 phosphatidylinositol 3-kinase complex(GO:0005942)
0.1 0.1 GO:0034704 cation channel complex(GO:0034703) calcium channel complex(GO:0034704)
0.1 2.7 GO:0031616 spindle pole centrosome(GO:0031616)
0.1 0.5 GO:0031673 H zone(GO:0031673)
0.1 1.6 GO:0005641 nuclear envelope lumen(GO:0005641)
0.1 0.4 GO:0044299 C-fiber(GO:0044299)
0.1 0.7 GO:0097513 myosin II filament(GO:0097513)
0.1 0.9 GO:0005775 vacuolar lumen(GO:0005775)
0.1 0.5 GO:0031523 Myb complex(GO:0031523)
0.1 1.0 GO:1990907 beta-catenin-TCF complex(GO:1990907)
0.1 1.3 GO:0005614 interstitial matrix(GO:0005614)
0.1 0.3 GO:0034702 ion channel complex(GO:0034702) transmembrane transporter complex(GO:1902495) transporter complex(GO:1990351)
0.1 0.5 GO:0005964 phosphorylase kinase complex(GO:0005964)
0.1 0.6 GO:0061574 ASAP complex(GO:0061574)
0.1 1.6 GO:0045334 clathrin-coated endocytic vesicle(GO:0045334)
0.1 0.3 GO:0090498 extrinsic component of Golgi membrane(GO:0090498)
0.1 0.3 GO:0044611 nuclear pore inner ring(GO:0044611)
0.1 0.8 GO:0031233 intrinsic component of external side of plasma membrane(GO:0031233)
0.0 0.4 GO:0031315 extrinsic component of mitochondrial outer membrane(GO:0031315)
0.0 0.8 GO:0032433 filopodium tip(GO:0032433)
0.0 0.2 GO:0000839 Hrd1p ubiquitin ligase ERAD-L complex(GO:0000839)
0.0 0.4 GO:0016593 Cdc73/Paf1 complex(GO:0016593)
0.0 0.2 GO:0001674 female germ cell nucleus(GO:0001674)
0.0 0.8 GO:0030665 clathrin-coated vesicle membrane(GO:0030665)
0.0 0.5 GO:0032045 guanyl-nucleotide exchange factor complex(GO:0032045)
0.0 0.2 GO:0098536 deuterosome(GO:0098536)
0.0 1.7 GO:0000307 cyclin-dependent protein kinase holoenzyme complex(GO:0000307)
0.0 0.5 GO:0030140 trans-Golgi network transport vesicle(GO:0030140)
0.0 1.7 GO:0005871 kinesin complex(GO:0005871)
0.0 0.1 GO:0032444 activin responsive factor complex(GO:0032444)
0.0 0.8 GO:0071339 MLL1/2 complex(GO:0044665) MLL1 complex(GO:0071339)
0.0 0.4 GO:0033017 sarcoplasmic reticulum membrane(GO:0033017)
0.0 1.5 GO:0005844 polysome(GO:0005844)
0.0 0.1 GO:1990130 Iml1 complex(GO:1990130)
0.0 0.1 GO:0045179 apical cortex(GO:0045179)
0.0 0.4 GO:0097228 sperm midpiece(GO:0097225) sperm principal piece(GO:0097228)
0.0 0.2 GO:0097136 Bcl-2 family protein complex(GO:0097136)
0.0 0.2 GO:1990635 proximal dendrite(GO:1990635)
0.0 0.0 GO:0045098 type III intermediate filament(GO:0045098)
0.0 0.4 GO:0032588 trans-Golgi network membrane(GO:0032588)
0.0 0.2 GO:0034098 VCP-NPL4-UFD1 AAA ATPase complex(GO:0034098)
0.0 1.8 GO:0005923 bicellular tight junction(GO:0005923)
0.0 2.6 GO:0009897 external side of plasma membrane(GO:0009897)
0.0 0.1 GO:0016580 Sin3 complex(GO:0016580)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 1.4 GO:0004774 succinate-CoA ligase activity(GO:0004774)
0.4 1.2 GO:0035373 chondroitin sulfate proteoglycan binding(GO:0035373)
0.4 2.8 GO:0046935 1-phosphatidylinositol-3-kinase regulator activity(GO:0046935)
0.3 1.8 GO:0008467 [heparan sulfate]-glucosamine 3-sulfotransferase 1 activity(GO:0008467)
0.2 1.0 GO:1902379 chemoattractant activity involved in axon guidance(GO:1902379)
0.2 1.1 GO:0019828 aspartic-type endopeptidase inhibitor activity(GO:0019828)
0.2 0.7 GO:0034437 glycoprotein transporter activity(GO:0034437)
0.2 2.8 GO:0008569 ATP-dependent microtubule motor activity, minus-end-directed(GO:0008569)
0.2 0.6 GO:0005436 sodium:phosphate symporter activity(GO:0005436) sodium:inorganic phosphate symporter activity(GO:0015319)
0.2 0.5 GO:0015140 malate transmembrane transporter activity(GO:0015140)
0.2 0.5 GO:0046538 bisphosphoglycerate mutase activity(GO:0004082) phosphoglycerate mutase activity(GO:0004619) 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase activity(GO:0046538)
0.2 1.0 GO:0030284 estrogen receptor activity(GO:0030284)
0.2 0.8 GO:0008427 calcium-dependent protein kinase inhibitor activity(GO:0008427)
0.1 1.2 GO:0043237 laminin-1 binding(GO:0043237)
0.1 0.8 GO:0004645 phosphorylase activity(GO:0004645)
0.1 0.5 GO:0034988 Fc-gamma receptor I complex binding(GO:0034988)
0.1 1.7 GO:0005537 mannose binding(GO:0005537)
0.1 0.9 GO:0001135 transcription factor activity, RNA polymerase II transcription factor recruiting(GO:0001135)
0.1 0.4 GO:0050632 propanoyl-CoA C-acyltransferase activity(GO:0033814) propionyl-CoA C2-trimethyltridecanoyltransferase activity(GO:0050632) phosphatidylethanolamine transporter activity(GO:1904121)
0.1 0.5 GO:0005030 neurotrophin receptor activity(GO:0005030)
0.1 0.3 GO:0019966 interleukin-1 binding(GO:0019966)
0.1 0.5 GO:0004468 lysine N-acetyltransferase activity, acting on acetyl phosphate as donor(GO:0004468)
0.1 0.5 GO:0051018 protein kinase A binding(GO:0051018)
0.1 0.5 GO:0004689 phosphorylase kinase activity(GO:0004689)
0.1 0.3 GO:0070815 peptidyl-lysine 5-dioxygenase activity(GO:0070815)
0.1 0.3 GO:0034739 histone deacetylase activity (H4-K16 specific)(GO:0034739)
0.1 0.4 GO:0051429 corticotropin-releasing hormone receptor binding(GO:0051429) corticotropin-releasing hormone receptor 1 binding(GO:0051430)
0.1 0.7 GO:0030306 ADP-ribosylation factor binding(GO:0030306)
0.1 0.3 GO:0001537 N-acetylgalactosamine 4-O-sulfotransferase activity(GO:0001537)
0.1 0.3 GO:0061575 cyclin-dependent protein serine/threonine kinase activator activity(GO:0061575)
0.1 0.3 GO:0035014 phosphatidylinositol 3-kinase regulator activity(GO:0035014)
0.1 0.4 GO:0051880 G-quadruplex DNA binding(GO:0051880)
0.1 0.2 GO:0004816 asparagine-tRNA ligase activity(GO:0004816)
0.1 0.7 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.1 0.3 GO:1990829 C-rich single-stranded DNA binding(GO:1990829)
0.1 0.7 GO:0005522 profilin binding(GO:0005522)
0.1 0.4 GO:0004767 sphingomyelin phosphodiesterase activity(GO:0004767)
0.1 0.2 GO:0008508 bile acid:sodium symporter activity(GO:0008508)
0.1 1.5 GO:0070064 proline-rich region binding(GO:0070064)
0.1 0.4 GO:0046934 phosphatidylinositol-4,5-bisphosphate 3-kinase activity(GO:0046934) phosphatidylinositol bisphosphate kinase activity(GO:0052813)
0.0 0.2 GO:0008545 JUN kinase kinase activity(GO:0008545)
0.0 0.3 GO:0048101 calmodulin-dependent cyclic-nucleotide phosphodiesterase activity(GO:0004117) calcium- and calmodulin-regulated 3',5'-cyclic-GMP phosphodiesterase activity(GO:0048101)
0.0 0.7 GO:0030898 actin-dependent ATPase activity(GO:0030898)
0.0 1.0 GO:0035613 RNA stem-loop binding(GO:0035613)
0.0 0.8 GO:0070016 armadillo repeat domain binding(GO:0070016)
0.0 0.8 GO:0043236 laminin binding(GO:0043236)
0.0 1.2 GO:0044183 protein binding involved in protein folding(GO:0044183)
0.0 3.4 GO:0003774 motor activity(GO:0003774)
0.0 0.1 GO:0048408 epidermal growth factor binding(GO:0048408)
0.0 0.6 GO:0008266 poly(U) RNA binding(GO:0008266)
0.0 0.2 GO:0038036 sphingosine-1-phosphate receptor activity(GO:0038036)
0.0 0.3 GO:0001618 virus receptor activity(GO:0001618)
0.0 0.4 GO:1904264 ubiquitin protein ligase activity involved in ERAD pathway(GO:1904264)
0.0 0.3 GO:0005225 volume-sensitive anion channel activity(GO:0005225)
0.0 0.1 GO:0030618 transforming growth factor beta receptor, pathway-specific cytoplasmic mediator activity(GO:0030618)
0.0 1.0 GO:0017112 Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.0 0.2 GO:0016618 hydroxypyruvate reductase activity(GO:0016618) glyoxylate reductase (NADP) activity(GO:0030267)
0.0 0.4 GO:0005035 tumor necrosis factor-activated receptor activity(GO:0005031) death receptor activity(GO:0005035)
0.0 0.8 GO:0005544 calcium-dependent phospholipid binding(GO:0005544)
0.0 0.2 GO:0034450 ubiquitin-ubiquitin ligase activity(GO:0034450)
0.0 0.2 GO:0051400 BH domain binding(GO:0051400)
0.0 2.5 GO:0008757 S-adenosylmethionine-dependent methyltransferase activity(GO:0008757)
0.0 0.4 GO:0005248 voltage-gated sodium channel activity(GO:0005248)
0.0 0.3 GO:0050321 tau-protein kinase activity(GO:0050321)
0.0 0.5 GO:0043027 cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027)
0.0 2.9 GO:0001047 core promoter binding(GO:0001047)
0.0 0.3 GO:0017056 structural constituent of nuclear pore(GO:0017056)
0.0 0.1 GO:0019956 chemokine binding(GO:0019956)
0.0 0.3 GO:1990841 promoter-specific chromatin binding(GO:1990841)
0.0 0.2 GO:0005149 interleukin-1 receptor binding(GO:0005149)
0.0 0.1 GO:0015129 lactate transmembrane transporter activity(GO:0015129)
0.0 0.5 GO:0008536 Ran GTPase binding(GO:0008536)
0.0 0.2 GO:0071949 FAD binding(GO:0071949)
0.0 0.1 GO:0010314 phosphatidylinositol-5-phosphate binding(GO:0010314)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.8 SA_REG_CASCADE_OF_CYCLIN_EXPR Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
0.1 3.2 PID_TRAIL_PATHWAY TRAIL signaling pathway
0.1 1.6 PID_ANTHRAX_PATHWAY Cellular roles of Anthrax toxin
0.1 2.7 PID_IL2_STAT5_PATHWAY IL2 signaling events mediated by STAT5
0.1 1.8 NABA_BASEMENT_MEMBRANES Genes encoding structural components of basement membranes
0.0 1.2 NABA_COLLAGENS Genes encoding collagen proteins
0.0 2.0 PID_ECADHERIN_STABILIZATION_PATHWAY Stabilization and expansion of the E-cadherin adherens junction
0.0 1.0 PID_WNT_SIGNALING_PATHWAY Wnt signaling network
0.0 1.7 PID_RB_1PATHWAY Regulation of retinoblastoma protein
0.0 1.3 PID_LKB1_PATHWAY LKB1 signaling events
0.0 0.2 PID_TCR_RAS_PATHWAY Ras signaling in the CD4+ TCR pathway
0.0 0.7 PID_INSULIN_GLUCOSE_PATHWAY Insulin-mediated glucose transport
0.0 1.7 PID_AR_PATHWAY Coregulation of Androgen receptor activity
0.0 0.7 PID_HNF3B_PATHWAY FOXA2 and FOXA3 transcription factor networks
0.0 0.5 PID_P75_NTR_PATHWAY p75(NTR)-mediated signaling
0.0 1.4 PID_BETA_CATENIN_NUC_PATHWAY Regulation of nuclear beta catenin signaling and target gene transcription
0.0 0.6 PID_FCER1_PATHWAY Fc-epsilon receptor I signaling in mast cells
0.0 0.5 SIG_REGULATION_OF_THE_ACTIN_CYTOSKELETON_BY_RHO_GTPASES Genes related to regulation of the actin cytoskeleton
0.0 0.3 PID_HDAC_CLASSIII_PATHWAY Signaling events mediated by HDAC Class III
0.0 0.5 PID_TAP63_PATHWAY Validated transcriptional targets of TAp63 isoforms
0.0 0.3 PID_IL8_CXCR2_PATHWAY IL8- and CXCR2-mediated signaling events
0.0 0.3 PID_ARF6_PATHWAY Arf6 signaling events
0.0 0.3 PID_FOXM1_PATHWAY FOXM1 transcription factor network
0.0 0.2 PID_S1P_META_PATHWAY Sphingosine 1-phosphate (S1P) pathway

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 2.8 REACTOME_IL_7_SIGNALING Genes involved in Interleukin-7 signaling
0.1 5.5 REACTOME_G1_PHASE Genes involved in G1 Phase
0.1 2.8 REACTOME_KINESINS Genes involved in Kinesins
0.1 1.6 REACTOME_GAP_JUNCTION_DEGRADATION Genes involved in Gap junction degradation
0.1 2.3 REACTOME_TIGHT_JUNCTION_INTERACTIONS Genes involved in Tight junction interactions
0.1 2.3 REACTOME_CELL_CELL_JUNCTION_ORGANIZATION Genes involved in Cell-cell junction organization
0.1 1.4 REACTOME_CITRIC_ACID_CYCLE_TCA_CYCLE Genes involved in Citric acid cycle (TCA cycle)
0.1 0.6 REACTOME_AMINE_DERIVED_HORMONES Genes involved in Amine-derived hormones
0.1 0.7 REACTOME_HDL_MEDIATED_LIPID_TRANSPORT Genes involved in HDL-mediated lipid transport
0.0 1.2 REACTOME_OTHER_SEMAPHORIN_INTERACTIONS Genes involved in Other semaphorin interactions
0.0 0.8 REACTOME_TIE2_SIGNALING Genes involved in Tie2 Signaling
0.0 1.2 REACTOME_ACTIVATED_NOTCH1_TRANSMITS_SIGNAL_TO_THE_NUCLEUS Genes involved in Activated NOTCH1 Transmits Signal to the Nucleus
0.0 0.5 REACTOME_TRAF3_DEPENDENT_IRF_ACTIVATION_PATHWAY Genes involved in TRAF3-dependent IRF activation pathway
0.0 0.4 REACTOME_SYNTHESIS_OF_BILE_ACIDS_AND_BILE_SALTS_VIA_7ALPHA_HYDROXYCHOLESTEROL Genes involved in Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol
0.0 0.5 REACTOME_GLYCOGEN_BREAKDOWN_GLYCOGENOLYSIS Genes involved in Glycogen breakdown (glycogenolysis)
0.0 0.4 REACTOME_MRNA_DECAY_BY_5_TO_3_EXORIBONUCLEASE Genes involved in mRNA Decay by 5' to 3' Exoribonuclease
0.0 0.6 REACTOME_SULFUR_AMINO_ACID_METABOLISM Genes involved in Sulfur amino acid metabolism
0.0 0.2 REACTOME_TRAF6_MEDIATED_IRF7_ACTIVATION_IN_TLR7_8_OR_9_SIGNALING Genes involved in TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling
0.0 0.3 REACTOME_P38MAPK_EVENTS Genes involved in p38MAPK events
0.0 0.5 REACTOME_ERK_MAPK_TARGETS Genes involved in ERK/MAPK targets
0.0 1.2 REACTOME_COLLAGEN_FORMATION Genes involved in Collagen formation
0.0 2.9 REACTOME_METABOLISM_OF_AMINO_ACIDS_AND_DERIVATIVES Genes involved in Metabolism of amino acids and derivatives
0.0 1.3 REACTOME_ANTIVIRAL_MECHANISM_BY_IFN_STIMULATED_GENES Genes involved in Antiviral mechanism by IFN-stimulated genes
0.0 1.4 REACTOME_CLASS_B_2_SECRETIN_FAMILY_RECEPTORS Genes involved in Class B/2 (Secretin family receptors)
0.0 0.5 REACTOME_SEMA4D_INDUCED_CELL_MIGRATION_AND_GROWTH_CONE_COLLAPSE Genes involved in Sema4D induced cell migration and growth-cone collapse
0.0 0.9 REACTOME_GOLGI_ASSOCIATED_VESICLE_BIOGENESIS Genes involved in Golgi Associated Vesicle Biogenesis
0.0 0.3 REACTOME_CGMP_EFFECTS Genes involved in cGMP effects
0.0 0.3 REACTOME_THE_ROLE_OF_NEF_IN_HIV1_REPLICATION_AND_DISEASE_PATHOGENESIS Genes involved in The role of Nef in HIV-1 replication and disease pathogenesis
0.0 0.2 REACTOME_JNK_C_JUN_KINASES_PHOSPHORYLATION_AND_ACTIVATION_MEDIATED_BY_ACTIVATED_HUMAN_TAK1 Genes involved in JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1
0.0 0.4 REACTOME_GLYCOSPHINGOLIPID_METABOLISM Genes involved in Glycosphingolipid metabolism
0.0 0.1 REACTOME_REGULATION_OF_WATER_BALANCE_BY_RENAL_AQUAPORINS Genes involved in Regulation of Water Balance by Renal Aquaporins