Motif ID: Hmx2

Z-value: 0.378


Transcription factors associated with Hmx2:

Gene SymbolEntrez IDGene Name
Hmx2 ENSMUSG00000050100.7 Hmx2

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Hmx2mm10_v2_chr7_+_131548755_131548773-0.212.2e-01Click!


Activity profile for motif Hmx2.

activity profile for motif Hmx2


Sorted Z-values histogram for motif Hmx2

Sorted Z-values for motif Hmx2



Network of associatons between targets according to the STRING database.



First level regulatory network of Hmx2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr14_+_73237891 1.503 ENSMUST00000044405.6
Lpar6
lysophosphatidic acid receptor 6
chr12_-_98901478 1.405 ENSMUST00000065716.6
Eml5
echinoderm microtubule associated protein like 5
chr5_-_28210022 1.364 ENSMUST00000118882.1
Cnpy1
canopy 1 homolog (zebrafish)
chr7_-_37772868 1.152 ENSMUST00000176205.1
Zfp536
zinc finger protein 536
chr5_+_3343893 1.068 ENSMUST00000165117.1
Cdk6
cyclin-dependent kinase 6
chr18_-_88894322 0.992 ENSMUST00000070116.5
ENSMUST00000125362.1
Socs6

suppressor of cytokine signaling 6

chr2_+_35132194 0.967 ENSMUST00000113034.1
ENSMUST00000113037.3
ENSMUST00000113033.2
Cep110


centrosomal protein 110


chr11_-_100822525 0.942 ENSMUST00000107358.2
Stat5b
signal transducer and activator of transcription 5B
chr10_+_128908907 0.823 ENSMUST00000105229.1
Cd63
CD63 antigen
chr4_-_132398199 0.814 ENSMUST00000136711.1
ENSMUST00000084249.4
Phactr4

phosphatase and actin regulator 4

chr8_-_123318553 0.781 ENSMUST00000118395.1
ENSMUST00000035495.8
Fanca

Fanconi anemia, complementation group A

chr19_-_58454435 0.759 ENSMUST00000169850.1
Gfra1
glial cell line derived neurotrophic factor family receptor alpha 1
chr5_-_53707532 0.753 ENSMUST00000031093.3
Cckar
cholecystokinin A receptor
chr18_-_34579072 0.734 ENSMUST00000079287.5
Nme5
NME/NM23 family member 5
chr6_-_137169678 0.699 ENSMUST00000119610.1
Rerg
RAS-like, estrogen-regulated, growth-inhibitor
chr18_+_50051702 0.698 ENSMUST00000134348.1
ENSMUST00000153873.2
Tnfaip8

tumor necrosis factor, alpha-induced protein 8

chr11_-_3931960 0.686 ENSMUST00000109990.1
ENSMUST00000020710.4
ENSMUST00000109989.3
ENSMUST00000109991.1
ENSMUST00000109993.2
Tcn2




transcobalamin 2




chr13_-_59675754 0.679 ENSMUST00000022039.5
ENSMUST00000095739.2
Golm1

golgi membrane protein 1

chr3_-_88410295 0.664 ENSMUST00000056370.7
Pmf1
polyamine-modulated factor 1
chr8_+_90828820 0.634 ENSMUST00000109614.2
ENSMUST00000048665.6
Chd9

chromodomain helicase DNA binding protein 9

chr3_+_94372794 0.595 ENSMUST00000029795.3
Rorc
RAR-related orphan receptor gamma
chr5_-_20951769 0.576 ENSMUST00000036489.5
Rsbn1l
round spermatid basic protein 1-like
chr14_-_48667508 0.575 ENSMUST00000144465.1
ENSMUST00000133479.1
ENSMUST00000119070.1
ENSMUST00000152018.1
Otx2



orthodenticle homolog 2 (Drosophila)



chr1_+_173420567 0.571 ENSMUST00000173023.1
Aim2
absent in melanoma 2
chr4_-_96553617 0.558 ENSMUST00000030303.5
Cyp2j6
cytochrome P450, family 2, subfamily j, polypeptide 6
chr12_+_72441852 0.558 ENSMUST00000162159.1
Lrrc9
leucine rich repeat containing 9
chr4_+_90218820 0.556 ENSMUST00000107129.1
Zfp352
zinc finger protein 352
chr12_-_90969768 0.549 ENSMUST00000181184.1
4930544I03Rik
RIKEN cDNA 4930544I03 gene
chr5_+_8893677 0.531 ENSMUST00000003717.8
Abcb4
ATP-binding cassette, sub-family B (MDR/TAP), member 4
chr6_+_71282280 0.523 ENSMUST00000080949.7
Krcc1
lysine-rich coiled-coil 1
chr11_-_96977660 0.517 ENSMUST00000107626.1
ENSMUST00000107624.1
Sp2

Sp2 transcription factor

chr4_-_26346882 0.515 ENSMUST00000041374.7
ENSMUST00000153813.1
Manea

mannosidase, endo-alpha

chr5_-_28210168 0.515 ENSMUST00000117098.1
Cnpy1
canopy 1 homolog (zebrafish)
chr5_+_23850590 0.497 ENSMUST00000181574.1
2700038G22Rik
RIKEN cDNA 2700038G22 gene
chr12_+_52699297 0.493 ENSMUST00000095737.3
Akap6
A kinase (PRKA) anchor protein 6
chr4_-_99829180 0.490 ENSMUST00000146258.1
Itgb3bp
integrin beta 3 binding protein (beta3-endonexin)
chr6_-_137169710 0.489 ENSMUST00000117919.1
Rerg
RAS-like, estrogen-regulated, growth-inhibitor
chr6_-_108185552 0.472 ENSMUST00000167338.1
ENSMUST00000172188.1
ENSMUST00000032191.9
Sumf1


sulfatase modifying factor 1


chr8_-_110902442 0.466 ENSMUST00000041382.6
Fuk
fucokinase
chr12_-_101913116 0.464 ENSMUST00000177536.1
ENSMUST00000176728.1
ENSMUST00000021605.7
Trip11


thyroid hormone receptor interactor 11


chrX_+_112615301 0.453 ENSMUST00000122805.1
Zfp711
zinc finger protein 711
chr4_+_145510759 0.447 ENSMUST00000105742.1
ENSMUST00000136309.1
Gm13225

predicted gene 13225

chr8_-_8690493 0.445 ENSMUST00000048545.8
Arglu1
arginine and glutamate rich 1
chrM_+_7759 0.445 ENSMUST00000082407.1
ENSMUST00000082408.1
mt-Atp8
mt-Atp6
mitochondrially encoded ATP synthase 8
mitochondrially encoded ATP synthase 6
chr3_-_116712644 0.423 ENSMUST00000029569.2
Slc35a3
solute carrier family 35 (UDP-N-acetylglucosamine (UDP-GlcNAc) transporter), member 3
chr4_-_45532470 0.417 ENSMUST00000147448.1
Shb
src homology 2 domain-containing transforming protein B
chr15_-_42676967 0.413 ENSMUST00000022921.5
Angpt1
angiopoietin 1
chr10_+_37139558 0.381 ENSMUST00000062667.3
5930403N24Rik
RIKEN cDNA 5930403N24 gene
chr1_+_91298354 0.380 ENSMUST00000142488.1
ENSMUST00000124832.1
ENSMUST00000147523.1
Scly


selenocysteine lyase


chr4_+_147492417 0.378 ENSMUST00000105721.2
Gm13152
predicted gene 13152
chr1_+_46066738 0.377 ENSMUST00000069293.7
Dnah7b
dynein, axonemal, heavy chain 7B
chr8_-_22694061 0.368 ENSMUST00000131767.1
Ikbkb
inhibitor of kappaB kinase beta
chr1_+_109993982 0.339 ENSMUST00000027542.6
Cdh7
cadherin 7, type 2
chr4_-_128962420 0.339 ENSMUST00000119354.1
ENSMUST00000106068.1
ENSMUST00000030581.3
Adc


arginine decarboxylase


chr6_+_29694204 0.334 ENSMUST00000046750.7
ENSMUST00000115250.3
Tspan33

tetraspanin 33

chr1_+_91298334 0.297 ENSMUST00000027532.6
Scly
selenocysteine lyase
chr9_+_35423582 0.296 ENSMUST00000154652.1
Cdon
cell adhesion molecule-related/down-regulated by oncogenes
chr7_-_133123409 0.292 ENSMUST00000170459.1
ENSMUST00000166400.1
Ctbp2

C-terminal binding protein 2

chr4_+_124880899 0.291 ENSMUST00000059343.6
Epha10
Eph receptor A10
chr10_-_22149270 0.289 ENSMUST00000179054.1
ENSMUST00000069372.6
E030030I06Rik

RIKEN cDNA E030030I06 gene

chr1_-_57970067 0.287 ENSMUST00000164963.1
Kctd18
potassium channel tetramerisation domain containing 18
chr7_-_133123770 0.285 ENSMUST00000164896.1
ENSMUST00000171968.1
Ctbp2

C-terminal binding protein 2

chrX_-_75578188 0.279 ENSMUST00000033545.5
Rab39b
RAB39B, member RAS oncogene family
chr3_+_106721672 0.260 ENSMUST00000098750.2
ENSMUST00000130105.1
Lrif1

ligand dependent nuclear receptor interacting factor 1

chr2_+_83644435 0.260 ENSMUST00000081591.6
Zc3h15
zinc finger CCCH-type containing 15
chr9_-_53667429 0.258 ENSMUST00000166367.1
ENSMUST00000034529.7
Cul5

cullin 5

chr4_-_94603239 0.246 ENSMUST00000107107.2
Plaa
phospholipase A2, activating protein
chr15_+_102407144 0.237 ENSMUST00000169619.1
Sp1
trans-acting transcription factor 1
chr8_+_34054622 0.234 ENSMUST00000149618.1
Gm9951
predicted gene 9951
chr10_+_63061582 0.228 ENSMUST00000020266.8
ENSMUST00000178684.1
Pbld1

phenazine biosynthesis-like protein domain containing 1

chr13_-_71963713 0.224 ENSMUST00000077337.8
Irx1
Iroquois related homeobox 1 (Drosophila)
chr9_-_122310921 0.219 ENSMUST00000180685.1
Gm26797
predicted gene, 26797
chr8_+_71922810 0.218 ENSMUST00000119003.1
Zfp617
zinc finger protein 617
chrX_-_56598069 0.217 ENSMUST00000059899.2
Mmgt1
membrane magnesium transporter 1
chr10_+_115569986 0.214 ENSMUST00000173620.1
A930009A15Rik
RIKEN cDNA A930009A15 gene
chr12_+_117843873 0.205 ENSMUST00000176735.1
ENSMUST00000177339.1
Cdca7l

cell division cycle associated 7 like

chr6_+_40471352 0.200 ENSMUST00000114779.2
ENSMUST00000031971.6
ENSMUST00000121360.1
ENSMUST00000117411.1
ENSMUST00000117830.1
Ssbp1




single-stranded DNA binding protein 1




chr4_+_133574728 0.199 ENSMUST00000030662.2
Gpatch3
G patch domain containing 3
chr1_-_57970104 0.189 ENSMUST00000114410.3
Kctd18
potassium channel tetramerisation domain containing 18
chr14_-_52213379 0.181 ENSMUST00000140603.1
Chd8
chromodomain helicase DNA binding protein 8
chr3_+_10088173 0.177 ENSMUST00000061419.7
Gm9833
predicted gene 9833
chr5_+_8660059 0.175 ENSMUST00000047753.4
Abcb1a
ATP-binding cassette, sub-family B (MDR/TAP), member 1A
chr9_-_54501496 0.167 ENSMUST00000118600.1
ENSMUST00000118163.1
Dmxl2

Dmx-like 2

chr9_-_50739365 0.163 ENSMUST00000117093.1
ENSMUST00000121634.1
Dixdc1

DIX domain containing 1

chr14_+_48446340 0.162 ENSMUST00000111735.2
Tmem260
transmembrane protein 260
chr11_-_78080360 0.159 ENSMUST00000021183.3
Eral1
Era (G-protein)-like 1 (E. coli)
chrX_-_164027965 0.158 ENSMUST00000033739.4
Car5b
carbonic anhydrase 5b, mitochondrial
chr13_-_107022027 0.158 ENSMUST00000117539.1
ENSMUST00000122233.1
ENSMUST00000022204.9
ENSMUST00000159772.1
Kif2a



kinesin family member 2A



chr5_-_31526693 0.156 ENSMUST00000118874.1
ENSMUST00000117642.1
ENSMUST00000065388.4
Supt7l


suppressor of Ty 7-like


chr5_-_140830430 0.154 ENSMUST00000000153.4
Gna12
guanine nucleotide binding protein, alpha 12
chr17_-_53539411 0.150 ENSMUST00000056198.3
Pp2d1
protein phosphatase 2C-like domain containing 1
chr10_-_37138863 0.149 ENSMUST00000092584.5
Marcks
myristoylated alanine rich protein kinase C substrate
chr5_-_131307848 0.142 ENSMUST00000086023.5
Wbscr17
Williams-Beuren syndrome chromosome region 17 homolog (human)
chr18_+_4993795 0.141 ENSMUST00000153016.1
Svil
supervillin
chr9_+_92457369 0.140 ENSMUST00000034941.7
Plscr4
phospholipid scramblase 4
chr4_+_145585166 0.122 ENSMUST00000105739.1
ENSMUST00000119718.1
Gm13212

predicted gene 13212

chr19_-_46969474 0.120 ENSMUST00000086961.7
Nt5c2
5'-nucleotidase, cytosolic II
chr9_-_113708209 0.115 ENSMUST00000111861.3
ENSMUST00000035086.6
Pdcd6ip

programmed cell death 6 interacting protein

chr3_-_87748619 0.112 ENSMUST00000023846.4
Lrrc71
leucine rich repeat containing 71
chr4_+_122836236 0.108 ENSMUST00000030412.4
ENSMUST00000121870.1
ENSMUST00000097902.4
Ppt1


palmitoyl-protein thioesterase 1


chr7_-_43505926 0.105 ENSMUST00000013497.1
ENSMUST00000163619.1
4931406B18Rik

RIKEN cDNA 4931406B18 gene

chr9_+_86485407 0.103 ENSMUST00000034987.8
Dopey1
dopey family member 1
chr15_+_85510812 0.096 ENSMUST00000079690.2
Gm4825
predicted pseudogene 4825
chr3_+_109573907 0.094 ENSMUST00000106576.2
Vav3
vav 3 oncogene
chr16_-_57167307 0.092 ENSMUST00000023432.8
Nit2
nitrilase family, member 2
chr5_-_131308076 0.092 ENSMUST00000160609.1
Wbscr17
Williams-Beuren syndrome chromosome region 17 homolog (human)
chr5_-_114380459 0.089 ENSMUST00000001125.5
Kctd10
potassium channel tetramerisation domain containing 10
chr7_-_45062393 0.085 ENSMUST00000129101.1
Prrg2
proline-rich Gla (G-carboxyglutamic acid) polypeptide 2
chr4_-_62470868 0.080 ENSMUST00000135811.1
ENSMUST00000120095.1
ENSMUST00000030087.7
ENSMUST00000107452.1
ENSMUST00000155522.1
Wdr31




WD repeat domain 31




chr8_+_25017211 0.066 ENSMUST00000033961.5
Tm2d2
TM2 domain containing 2
chr8_+_25808474 0.065 ENSMUST00000033979.4
Star
steroidogenic acute regulatory protein
chr1_-_180813534 0.064 ENSMUST00000159789.1
ENSMUST00000081026.4
H3f3a

H3 histone, family 3A

chrX_-_134111852 0.060 ENSMUST00000033610.6
Nox1
NADPH oxidase 1
chr5_-_114380505 0.060 ENSMUST00000102581.4
Kctd10
potassium channel tetramerisation domain containing 10
chr2_-_127444524 0.057 ENSMUST00000028848.3
Fahd2a
fumarylacetoacetate hydrolase domain containing 2A
chr3_-_65392579 0.049 ENSMUST00000029414.5
Ssr3
signal sequence receptor, gamma
chr3_+_66985947 0.046 ENSMUST00000161726.1
ENSMUST00000160504.1
Rsrc1

arginine/serine-rich coiled-coil 1

chr1_+_164275559 0.046 ENSMUST00000027867.6
Ccdc181
coiled-coil domain containing 181
chr3_+_124321031 0.040 ENSMUST00000058994.4
Tram1l1
translocation associated membrane protein 1-like 1
chr10_+_69925766 0.040 ENSMUST00000182269.1
ENSMUST00000183261.1
ENSMUST00000183074.1
Ank3


ankyrin 3, epithelial


chr4_-_56947411 0.035 ENSMUST00000107609.3
ENSMUST00000068792.6
Tmem245

transmembrane protein 245

chr13_-_58354862 0.032 ENSMUST00000043605.5
Kif27
kinesin family member 27
chr18_-_65939048 0.028 ENSMUST00000025396.3
Rax
retina and anterior neural fold homeobox
chr5_-_28467093 0.027 ENSMUST00000002708.3
Shh
sonic hedgehog
chr5_-_138272733 0.024 ENSMUST00000161665.1
ENSMUST00000100530.1
Gal3st4

galactose-3-O-sulfotransferase 4

chr10_-_19907645 0.023 ENSMUST00000166511.1
ENSMUST00000020182.8
Pex7

peroxisomal biogenesis factor 7

chr16_+_17619341 0.011 ENSMUST00000006053.6
ENSMUST00000171435.1
ENSMUST00000163476.1
ENSMUST00000168101.1
ENSMUST00000165363.1
ENSMUST00000169662.1
ENSMUST00000090159.4
ENSMUST00000172182.1
ENSMUST00000163592.1
Smpd4








sphingomyelin phosphodiesterase 4








chr10_+_69925800 0.005 ENSMUST00000182029.1
Ank3
ankyrin 3, epithelial
chr5_+_114380591 0.001 ENSMUST00000074002.5
Ube3b
ubiquitin protein ligase E3B

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 0.9 GO:0046544 regulation of natural killer cell proliferation(GO:0032817) positive regulation of natural killer cell proliferation(GO:0032819) development of secondary male sexual characteristics(GO:0046544)
0.3 0.8 GO:0090274 positive regulation of somatostatin secretion(GO:0090274)
0.2 0.8 GO:2001045 closure of optic fissure(GO:0061386) negative regulation of integrin-mediated signaling pathway(GO:2001045)
0.2 0.6 GO:0035359 negative regulation of peroxisome proliferator activated receptor signaling pathway(GO:0035359)
0.2 0.7 GO:0015889 cobalamin transport(GO:0015889)
0.2 0.7 GO:0001887 selenium compound metabolic process(GO:0001887) selenocysteine metabolic process(GO:0016259)
0.2 0.8 GO:2000680 regulation of rubidium ion transport(GO:2000680)
0.2 1.1 GO:0044838 cell quiescence(GO:0044838)
0.1 0.6 GO:0046552 eye photoreceptor cell fate commitment(GO:0042706) photoreceptor cell fate commitment(GO:0046552)
0.1 0.6 GO:0070269 pyroptosis(GO:0070269)
0.1 0.4 GO:0030210 heparin biosynthetic process(GO:0030210)
0.1 0.5 GO:0060316 positive regulation of ryanodine-sensitive calcium-release channel activity(GO:0060316)
0.1 0.5 GO:0046368 GDP-L-fucose metabolic process(GO:0046368)
0.1 0.4 GO:0015788 UDP-N-acetylglucosamine transport(GO:0015788)
0.1 0.5 GO:0034080 CENP-A containing nucleosome assembly(GO:0034080) CENP-A containing chromatin organization(GO:0061641)
0.1 1.2 GO:0048387 negative regulation of retinoic acid receptor signaling pathway(GO:0048387)
0.1 0.2 GO:0060392 negative regulation of SMAD protein import into nucleus(GO:0060392)
0.1 0.5 GO:0061092 bile acid secretion(GO:0032782) regulation of phospholipid translocation(GO:0061091) positive regulation of phospholipid translocation(GO:0061092)
0.1 0.6 GO:0072615 interleukin-17 secretion(GO:0072615)
0.1 0.4 GO:1903347 negative regulation of bicellular tight junction assembly(GO:1903347)
0.1 1.5 GO:0051482 positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G-protein coupled signaling pathway(GO:0051482)
0.1 0.7 GO:0006228 UTP biosynthetic process(GO:0006228)
0.1 0.6 GO:0048386 positive regulation of retinoic acid receptor signaling pathway(GO:0048386)
0.1 0.2 GO:0072272 proximal/distal pattern formation involved in metanephric nephron development(GO:0072272)
0.0 0.4 GO:1900194 negative regulation of oocyte maturation(GO:1900194)
0.0 0.2 GO:0046618 drug export(GO:0046618)
0.0 0.1 GO:0044837 assembly of actomyosin apparatus involved in cytokinesis(GO:0000912) actomyosin contractile ring assembly(GO:0000915) actomyosin contractile ring organization(GO:0044837)
0.0 0.3 GO:0014816 skeletal muscle satellite cell differentiation(GO:0014816)
0.0 0.5 GO:0003413 chondrocyte differentiation involved in endochondral bone morphogenesis(GO:0003413)
0.0 0.2 GO:2000348 regulation of CD40 signaling pathway(GO:2000348)
0.0 0.2 GO:0010992 ubiquitin homeostasis(GO:0010992)
0.0 0.4 GO:0036159 inner dynein arm assembly(GO:0036159)
0.0 0.2 GO:0070814 hydrogen sulfide biosynthetic process(GO:0070814)
0.0 0.2 GO:0051096 positive regulation of helicase activity(GO:0051096)
0.0 0.2 GO:0006824 cobalt ion transport(GO:0006824)
0.0 0.3 GO:0021942 radial glia guided migration of Purkinje cell(GO:0021942)
0.0 0.2 GO:0070072 vacuolar proton-transporting V-type ATPase complex assembly(GO:0070072)
0.0 0.1 GO:0098734 protein depalmitoylation(GO:0002084) positive regulation of pinocytosis(GO:0048549) macromolecule depalmitoylation(GO:0098734)
0.0 0.4 GO:0015985 energy coupled proton transport, down electrochemical gradient(GO:0015985) ATP synthesis coupled proton transport(GO:0015986)
0.0 0.2 GO:2000270 negative regulation of fibroblast apoptotic process(GO:2000270)
0.0 0.1 GO:0070859 positive regulation of bile acid biosynthetic process(GO:0070859) positive regulation of bile acid metabolic process(GO:1904253)
0.0 0.1 GO:1902340 telomeric heterochromatin assembly(GO:0031509) negative regulation of chromosome condensation(GO:1902340)
0.0 0.1 GO:0006528 asparagine metabolic process(GO:0006528)
0.0 0.1 GO:0072592 regulation of integrin biosynthetic process(GO:0045113) oxygen metabolic process(GO:0072592)
0.0 0.2 GO:0021869 forebrain ventricular zone progenitor cell division(GO:0021869)
0.0 1.0 GO:1904893 negative regulation of JAK-STAT cascade(GO:0046426) negative regulation of STAT cascade(GO:1904893)
0.0 0.7 GO:0032611 interleukin-1 beta production(GO:0032611)
0.0 0.1 GO:0046085 adenosine metabolic process(GO:0046085)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.8 GO:0097487 multivesicular body, internal vesicle(GO:0097487)
0.1 0.6 GO:0061702 inflammasome complex(GO:0061702)
0.1 0.4 GO:0036156 inner dynein arm(GO:0036156)
0.1 0.7 GO:0000444 MIS12/MIND type complex(GO:0000444)
0.1 0.7 GO:0046581 intercellular canaliculus(GO:0046581)
0.1 0.8 GO:0043240 Fanconi anaemia nuclear complex(GO:0043240)
0.1 0.3 GO:0031466 Cul5-RING ubiquitin ligase complex(GO:0031466)
0.0 0.1 GO:0042585 germinal vesicle(GO:0042585)
0.0 0.3 GO:0097197 tetraspanin-enriched microdomain(GO:0097197)
0.0 0.4 GO:0000276 mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276)
0.0 0.4 GO:0008385 IkappaB kinase complex(GO:0008385)
0.0 0.6 GO:0097470 ribbon synapse(GO:0097470)
0.0 0.5 GO:0005640 nuclear outer membrane(GO:0005640)
0.0 1.1 GO:0001772 immunological synapse(GO:0001772)
0.0 0.5 GO:0002080 acrosomal membrane(GO:0002080)
0.0 1.1 GO:0000307 cyclin-dependent protein kinase holoenzyme complex(GO:0000307)
0.0 0.2 GO:0072546 ER membrane protein complex(GO:0072546)
0.0 0.1 GO:0071438 invadopodium membrane(GO:0071438)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.1 GO:0098770 FBXO family protein binding(GO:0098770)
0.2 1.5 GO:0070915 lysophosphatidic acid receptor activity(GO:0070915)
0.2 0.6 GO:0008392 arachidonic acid epoxygenase activity(GO:0008392)
0.2 0.7 GO:0070279 vitamin B6 binding(GO:0070279)
0.2 0.8 GO:0072542 protein phosphatase activator activity(GO:0072542)
0.1 0.6 GO:0008142 oxysterol binding(GO:0008142)
0.1 0.7 GO:0008559 xenobiotic-transporting ATPase activity(GO:0008559) phosphatidylcholine-translocating ATPase activity(GO:0090554)
0.1 0.4 GO:0008384 IkappaB kinase activity(GO:0008384)
0.1 0.7 GO:0031419 cobalamin binding(GO:0031419)
0.1 1.2 GO:0044323 retinoic acid-responsive element binding(GO:0044323)
0.1 0.6 GO:0016618 hydroxypyruvate reductase activity(GO:0016618) glyoxylate reductase (NADP) activity(GO:0030267)
0.1 0.7 GO:0043522 leucine zipper domain binding(GO:0043522)
0.1 0.2 GO:0031752 D5 dopamine receptor binding(GO:0031752)
0.0 0.3 GO:0005005 transmembrane-ephrin receptor activity(GO:0005005)
0.0 0.1 GO:0031871 proteinase activated receptor binding(GO:0031871)
0.0 0.7 GO:0004550 nucleoside diphosphate kinase activity(GO:0004550)
0.0 0.5 GO:0043495 protein anchor(GO:0043495)
0.0 0.5 GO:0004559 alpha-mannosidase activity(GO:0004559)
0.0 0.4 GO:0005172 vascular endothelial growth factor receptor binding(GO:0005172)
0.0 0.2 GO:0015087 cobalt ion transmembrane transporter activity(GO:0015087)
0.0 0.4 GO:0008569 ATP-dependent microtubule motor activity, minus-end-directed(GO:0008569)
0.0 0.9 GO:0035259 glucocorticoid receptor binding(GO:0035259)
0.0 0.2 GO:0016004 phospholipase activator activity(GO:0016004) lipase activator activity(GO:0060229)
0.0 0.1 GO:0030171 voltage-gated proton channel activity(GO:0030171)
0.0 0.4 GO:0005351 sugar:proton symporter activity(GO:0005351)
0.0 0.7 GO:0043027 cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027)
0.0 0.2 GO:0043024 ribosomal small subunit binding(GO:0043024)
0.0 0.1 GO:0042609 CD4 receptor binding(GO:0042609)
0.0 0.8 GO:0008528 G-protein coupled peptide receptor activity(GO:0008528)
0.0 0.2 GO:0004089 carbonate dehydratase activity(GO:0004089)
0.0 0.3 GO:0031489 myosin V binding(GO:0031489)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.9 PID_IL5_PATHWAY IL5-mediated signaling events
0.0 1.3 PID_IL2_STAT5_PATHWAY IL2 signaling events mediated by STAT5
0.0 0.8 PID_BARD1_PATHWAY BARD1 signaling events
0.0 0.8 PID_RET_PATHWAY Signaling events regulated by Ret tyrosine kinase
0.0 0.4 PID_NFKAPPAB_ATYPICAL_PATHWAY Atypical NF-kappaB pathway
0.0 0.4 PID_PDGFRA_PATHWAY PDGFR-alpha signaling pathway
0.0 0.2 PID_S1P_S1P4_PATHWAY S1P4 pathway
0.0 0.3 PID_HEDGEHOG_2PATHWAY Signaling events mediated by the Hedgehog family

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.5 REACTOME_P2Y_RECEPTORS Genes involved in P2Y receptors
0.1 0.9 REACTOME_PROLACTIN_RECEPTOR_SIGNALING Genes involved in Prolactin receptor signaling
0.1 0.5 REACTOME_THE_ACTIVATION_OF_ARYLSULFATASES Genes involved in The activation of arylsulfatases
0.0 1.0 REACTOME_REGULATION_OF_KIT_SIGNALING Genes involved in Regulation of KIT signaling
0.0 0.6 REACTOME_INFLAMMASOMES Genes involved in Inflammasomes
0.0 0.4 REACTOME_IKK_COMPLEX_RECRUITMENT_MEDIATED_BY_RIP1 Genes involved in IKK complex recruitment mediated by RIP1
0.0 0.5 REACTOME_NRIF_SIGNALS_CELL_DEATH_FROM_THE_NUCLEUS Genes involved in NRIF signals cell death from the nucleus
0.0 0.8 REACTOME_FANCONI_ANEMIA_PATHWAY Genes involved in Fanconi Anemia pathway
0.0 1.1 REACTOME_G1_PHASE Genes involved in G1 Phase
0.0 0.1 REACTOME_REGULATION_OF_INSULIN_SECRETION_BY_ACETYLCHOLINE Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.0 0.8 REACTOME_NCAM1_INTERACTIONS Genes involved in NCAM1 interactions
0.0 0.1 REACTOME_ABACAVIR_TRANSPORT_AND_METABOLISM Genes involved in Abacavir transport and metabolism
0.0 0.4 REACTOME_TRANSPORT_OF_VITAMINS_NUCLEOSIDES_AND_RELATED_MOLECULES Genes involved in Transport of vitamins, nucleosides, and related molecules