Motif ID: Hnf1b

Z-value: 0.449


Transcription factors associated with Hnf1b:

Gene SymbolEntrez IDGene Name
Hnf1b ENSMUSG00000020679.5 Hnf1b



Activity profile for motif Hnf1b.

activity profile for motif Hnf1b


Sorted Z-values histogram for motif Hnf1b

Sorted Z-values for motif Hnf1b



Network of associatons between targets according to the STRING database.



First level regulatory network of Hnf1b

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr1_-_158814469 2.815 ENSMUST00000161589.2
Pappa2
pappalysin 2
chr13_-_53286052 1.941 ENSMUST00000021918.8
Ror2
receptor tyrosine kinase-like orphan receptor 2
chr13_+_4191163 1.713 ENSMUST00000021634.2
Akr1c13
aldo-keto reductase family 1, member C13
chr1_+_133309778 1.357 ENSMUST00000094557.4
ENSMUST00000183457.1
ENSMUST00000183738.1
ENSMUST00000185157.1
ENSMUST00000184603.1
Golt1a

Kiss1

GOLT1A
golgi transport 1 homolog A (S. cerevisiae)

KiSS-1 metastasis-suppressor

KISS1 isoform e
chr19_-_14598031 1.343 ENSMUST00000167776.2
Tle4
transducin-like enhancer of split 4, homolog of Drosophila E(spl)
chr19_-_14597983 1.296 ENSMUST00000052011.7
Tle4
transducin-like enhancer of split 4, homolog of Drosophila E(spl)
chr13_+_55152640 1.042 ENSMUST00000005452.5
Fgfr4
fibroblast growth factor receptor 4
chr7_+_100537192 1.010 ENSMUST00000120454.1
Coa4
cytochrome c oxidase assembly factor 4
chr2_+_158768083 0.989 ENSMUST00000029183.2
Fam83d
family with sequence similarity 83, member D
chr4_+_43957401 0.880 ENSMUST00000030202.7
Glipr2
GLI pathogenesis-related 2
chr19_+_23723279 0.804 ENSMUST00000067077.1
Gm9938
predicted gene 9938
chr16_-_16146771 0.691 ENSMUST00000040248.7
Spidr
scaffolding protein involved i DNA repair
chr10_-_7212222 0.621 ENSMUST00000015346.5
Cnksr3
Cnksr family member 3
chr12_+_108605757 0.619 ENSMUST00000109854.2
Evl
Ena-vasodilator stimulated phosphoprotein
chr9_+_99629496 0.601 ENSMUST00000131095.1
ENSMUST00000078367.5
ENSMUST00000112885.2
Dzip1l


DAZ interacting protein 1-like


chr7_-_119895446 0.598 ENSMUST00000098080.2
Dcun1d3
DCN1, defective in cullin neddylation 1, domain containing 3 (S. cerevisiae)
chr15_-_103215285 0.594 ENSMUST00000122182.1
ENSMUST00000108813.3
ENSMUST00000127191.1
Cbx5


chromobox 5


chr4_+_150853919 0.579 ENSMUST00000073600.2
Errfi1
ERBB receptor feedback inhibitor 1
chr12_+_5411641 0.567 ENSMUST00000163627.1
2810032G03Rik
RIKEN cDNA 2810032G03 gene
chr17_-_35132050 0.566 ENSMUST00000025249.6
Apom
apolipoprotein M
chr9_-_106158109 0.563 ENSMUST00000159809.1
ENSMUST00000162562.1
ENSMUST00000036382.6
ENSMUST00000112543.2
Glyctk



glycerate kinase



chr15_-_100425050 0.554 ENSMUST00000123461.1
Slc11a2
solute carrier family 11 (proton-coupled divalent metal ion transporters), member 2
chr9_+_99629823 0.551 ENSMUST00000112886.2
Dzip1l
DAZ interacting protein 1-like
chr6_-_102464667 0.527 ENSMUST00000032159.6
Cntn3
contactin 3
chr7_+_141216626 0.525 ENSMUST00000141804.1
ENSMUST00000148975.1
Rassf7

Ras association (RalGDS/AF-6) domain family (N-terminal) member 7

chr10_-_76110956 0.501 ENSMUST00000120757.1
Slc5a4b
solute carrier family 5 (neutral amino acid transporters, system A), member 4b
chr7_+_24862193 0.465 ENSMUST00000052897.4
ENSMUST00000170837.2
Gm9844
Gm9844
predicted pseudogene 9844
predicted pseudogene 9844
chr3_+_154597352 0.458 ENSMUST00000140644.1
ENSMUST00000144764.1
ENSMUST00000155232.1
Cryz


crystallin, zeta


chr1_+_133246092 0.445 ENSMUST00000038295.8
ENSMUST00000105082.2
Plekha6

pleckstrin homology domain containing, family A member 6

chr5_-_123666682 0.421 ENSMUST00000149410.1
Clip1
CAP-GLY domain containing linker protein 1
chr2_-_86347764 0.408 ENSMUST00000099894.2
Olfr1055
olfactory receptor 1055
chr9_+_15520830 0.403 ENSMUST00000178999.1
Smco4
single-pass membrane protein with coiled-coil domains 4
chr7_-_45062393 0.395 ENSMUST00000129101.1
Prrg2
proline-rich Gla (G-carboxyglutamic acid) polypeptide 2
chr7_+_141215852 0.374 ENSMUST00000046890.5
ENSMUST00000133763.1
Rassf7

Ras association (RalGDS/AF-6) domain family (N-terminal) member 7

chr15_-_10713537 0.372 ENSMUST00000090339.3
Rai14
retinoic acid induced 14
chr18_+_4993795 0.370 ENSMUST00000153016.1
Svil
supervillin
chr1_-_12991109 0.363 ENSMUST00000115403.2
ENSMUST00000115402.1
Slco5a1

solute carrier organic anion transporter family, member 5A1

chr1_+_125676969 0.339 ENSMUST00000027581.6
Gpr39
G protein-coupled receptor 39
chr9_+_53771499 0.331 ENSMUST00000048670.8
Slc35f2
solute carrier family 35, member F2
chr13_+_4233730 0.319 ENSMUST00000081326.6
Akr1c19
aldo-keto reductase family 1, member C19
chr11_+_4883186 0.280 ENSMUST00000139737.1
Nipsnap1
4-nitrophenylphosphatase domain and non-neuronal SNAP25-like protein homolog 1 (C. elegans)
chr9_+_67840386 0.276 ENSMUST00000077879.5
Vps13c
vacuolar protein sorting 13C (yeast)
chr14_+_48446128 0.275 ENSMUST00000124720.1
Tmem260
transmembrane protein 260
chr12_-_12940600 0.265 ENSMUST00000130990.1
Mycn
v-myc myelocytomatosis viral related oncogene, neuroblastoma derived (avian)
chr2_+_173737492 0.263 ENSMUST00000067530.4
Vapb
vesicle-associated membrane protein, associated protein B and C
chr1_+_74661794 0.258 ENSMUST00000129890.1
Ttll4
tubulin tyrosine ligase-like family, member 4
chr3_-_108226598 0.236 ENSMUST00000029486.7
ENSMUST00000156371.1
ENSMUST00000141387.1
Sypl2


synaptophysin-like 2


chr4_-_108144986 0.234 ENSMUST00000130776.1
Scp2
sterol carrier protein 2, liver
chr6_+_73248382 0.228 ENSMUST00000064740.6
Suclg1
succinate-CoA ligase, GDP-forming, alpha subunit
chr9_+_108795971 0.226 ENSMUST00000085018.4
Ip6k2
inositol hexaphosphate kinase 2
chr19_-_30549516 0.220 ENSMUST00000025803.8
Dkk1
dickkopf homolog 1 (Xenopus laevis)
chr3_-_138131356 0.211 ENSMUST00000029805.8
Mttp
microsomal triglyceride transfer protein
chr19_-_57197496 0.204 ENSMUST00000111544.1
Ablim1
actin-binding LIM protein 1
chr19_+_60889749 0.204 ENSMUST00000003313.8
Grk5
G protein-coupled receptor kinase 5
chr9_-_71163224 0.189 ENSMUST00000074465.2
Aqp9
aquaporin 9
chr9_-_44767792 0.189 ENSMUST00000034607.9
Arcn1
archain 1
chr11_-_98022594 0.173 ENSMUST00000103144.3
ENSMUST00000017552.6
ENSMUST00000092736.4
ENSMUST00000107562.1
Cacnb1



calcium channel, voltage-dependent, beta 1 subunit



chr5_-_100373484 0.165 ENSMUST00000182433.1
Sec31a
Sec31 homolog A (S. cerevisiae)
chr13_-_55536504 0.155 ENSMUST00000021956.8
Ddx41
DEAD (Asp-Glu-Ala-Asp) box polypeptide 41
chr9_+_109096659 0.152 ENSMUST00000130366.1
Plxnb1
plexin B1
chr18_-_66022580 0.151 ENSMUST00000143990.1
Lman1
lectin, mannose-binding, 1
chr1_-_4880669 0.151 ENSMUST00000078030.3
Gm6104
predicted gene 6104
chr7_-_29505447 0.150 ENSMUST00000183096.1
ENSMUST00000085809.4
Sipa1l3

signal-induced proliferation-associated 1 like 3

chr10_+_128411616 0.149 ENSMUST00000096386.5
ENSMUST00000171342.1
Rnf41

ring finger protein 41

chr11_+_3983636 0.146 ENSMUST00000078757.1
Gal3st1
galactose-3-O-sulfotransferase 1
chr14_+_48446340 0.145 ENSMUST00000111735.2
Tmem260
transmembrane protein 260
chr12_+_87443896 0.142 ENSMUST00000161023.1
ENSMUST00000160488.1
ENSMUST00000077462.7
ENSMUST00000160880.1
Slirp



SRA stem-loop interacting RNA binding protein



chr8_-_22694061 0.140 ENSMUST00000131767.1
Ikbkb
inhibitor of kappaB kinase beta
chr19_+_27217011 0.136 ENSMUST00000164746.1
ENSMUST00000172302.1
Vldlr

very low density lipoprotein receptor

chr1_+_19208914 0.135 ENSMUST00000027059.4
Tfap2b
transcription factor AP-2 beta
chr11_+_3983704 0.135 ENSMUST00000063004.7
Gal3st1
galactose-3-O-sulfotransferase 1
chr7_-_144751968 0.130 ENSMUST00000155175.1
Ano1
anoctamin 1, calcium activated chloride channel
chr5_-_121527186 0.130 ENSMUST00000152270.1
Mapkapk5
MAP kinase-activated protein kinase 5
chr7_-_27166732 0.127 ENSMUST00000080058.4
Egln2
EGL nine homolog 2 (C. elegans)
chr6_-_128437653 0.121 ENSMUST00000151796.1
Fkbp4
FK506 binding protein 4
chr3_-_130730375 0.119 ENSMUST00000079085.6
Rpl34
ribosomal protein L34
chr12_+_4769375 0.116 ENSMUST00000178879.1
Pfn4
profilin family, member 4
chr17_+_17374332 0.115 ENSMUST00000024620.6
Riok2
RIO kinase 2 (yeast)
chr5_-_87490869 0.110 ENSMUST00000147854.1
Ugt2a1
UDP glucuronosyltransferase 2 family, polypeptide A1
chr12_+_76533540 0.110 ENSMUST00000075249.4
Plekhg3
pleckstrin homology domain containing, family G (with RhoGef domain) member 3
chr9_+_54538984 0.102 ENSMUST00000060242.5
ENSMUST00000118413.1
Sh2d7

SH2 domain containing 7

chr2_+_167777467 0.102 ENSMUST00000139927.1
ENSMUST00000127441.1
Gm14321

predicted gene 14321

chr8_+_95332279 0.099 ENSMUST00000034245.8
Usb1
U6 snRNA biogenesis 1
chr10_+_4611971 0.090 ENSMUST00000105590.1
ENSMUST00000067086.7
Esr1

estrogen receptor 1 (alpha)

chr7_+_27731398 0.089 ENSMUST00000130997.1
Zfp60
zinc finger protein 60
chr11_+_110968056 0.088 ENSMUST00000125692.1
Kcnj16
potassium inwardly-rectifying channel, subfamily J, member 16
chr7_+_33653440 0.078 ENSMUST00000151344.1
Gm12763
predicted gene 12763
chr14_-_20496780 0.072 ENSMUST00000022353.3
Mss51
MSS51 mitochondrial translational activator
chr3_-_89365233 0.071 ENSMUST00000070820.6
Dcst1
DC-STAMP domain containing 1
chr11_+_118428203 0.067 ENSMUST00000124861.1
C1qtnf1
C1q and tumor necrosis factor related protein 1
chr9_+_95857597 0.066 ENSMUST00000034980.7
Atr
ataxia telangiectasia and Rad3 related
chr6_-_38124568 0.062 ENSMUST00000040259.4
Atp6v0a4
ATPase, H+ transporting, lysosomal V0 subunit A4
chr19_-_57197556 0.062 ENSMUST00000099294.2
Ablim1
actin-binding LIM protein 1
chr13_+_89540636 0.057 ENSMUST00000022108.7
Hapln1
hyaluronan and proteoglycan link protein 1
chr17_-_71459300 0.057 ENSMUST00000183937.1
Gm4707
predicted gene 4707
chr13_+_66932802 0.056 ENSMUST00000021990.3
Ptdss1
phosphatidylserine synthase 1
chr11_+_78465697 0.047 ENSMUST00000001126.3
Slc46a1
solute carrier family 46, member 1
chr10_-_116549101 0.044 ENSMUST00000164088.1
Cnot2
CCR4-NOT transcription complex, subunit 2
chr5_-_114443993 0.044 ENSMUST00000112245.1
Mmab
methylmalonic aciduria (cobalamin deficiency) type B homolog (human)
chr9_+_54980880 0.043 ENSMUST00000093844.3
Chrna5
cholinergic receptor, nicotinic, alpha polypeptide 5
chr14_-_36919314 0.038 ENSMUST00000182797.1
Ccser2
coiled-coil serine rich 2
chr3_-_150073620 0.037 ENSMUST00000057740.5
Rpsa-ps10
ribosomal protein SA, pseudogene 10
chr14_+_46882854 0.033 ENSMUST00000022386.8
ENSMUST00000100672.3
Samd4

sterile alpha motif domain containing 4

chrX_-_95444789 0.031 ENSMUST00000084535.5
Amer1
APC membrane recruitment 1
chr14_-_36919513 0.028 ENSMUST00000182042.1
Ccser2
coiled-coil serine rich 2
chr15_+_99393610 0.027 ENSMUST00000159531.1
Tmbim6
transmembrane BAX inhibitor motif containing 6
chr15_-_96699698 0.025 ENSMUST00000023099.6
Slc38a2
solute carrier family 38, member 2
chr17_-_33718591 0.023 ENSMUST00000174040.1
ENSMUST00000173015.1
ENSMUST00000066121.6
ENSMUST00000172767.1
ENSMUST00000173329.1
March2




membrane-associated ring finger (C3HC4) 2




chr12_-_87444017 0.022 ENSMUST00000091090.4
2700073G19Rik
RIKEN cDNA 2700073G19 gene
chr4_-_140617062 0.021 ENSMUST00000154979.1
Arhgef10l
Rho guanine nucleotide exchange factor (GEF) 10-like
chr8_-_92355764 0.020 ENSMUST00000180102.1
ENSMUST00000179421.1
ENSMUST00000179222.1
ENSMUST00000179029.1
4933436C20Rik



RIKEN cDNA 4933436C20 gene



chr11_+_116848901 0.017 ENSMUST00000143184.1
Mettl23
methyltransferase like 23
chr11_+_110968016 0.011 ENSMUST00000106636.1
ENSMUST00000180023.1
Kcnj16

potassium inwardly-rectifying channel, subfamily J, member 16

chr13_-_73678005 0.007 ENSMUST00000022105.7
ENSMUST00000109680.2
ENSMUST00000109679.2
Slc6a18


solute carrier family 6 (neurotransmitter transporter), member 18


chr8_+_70724064 0.006 ENSMUST00000034307.7
ENSMUST00000110095.2
Pde4c

phosphodiesterase 4C, cAMP specific

chrX_+_101449078 0.005 ENSMUST00000033674.5
Itgb1bp2
integrin beta 1 binding protein 2
chr7_+_119561699 0.002 ENSMUST00000167935.2
ENSMUST00000130583.1
Acsm2

acyl-CoA synthetase medium-chain family member 2

chr8_+_117095854 0.002 ENSMUST00000034308.8
ENSMUST00000167370.1
ENSMUST00000176860.1
Bcmo1


beta-carotene 15,15'-monooxygenase


chr3_-_130730310 0.000 ENSMUST00000062601.7
Rpl34
ribosomal protein L34

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.9 GO:0007223 Wnt signaling pathway, calcium modulating pathway(GO:0007223)
0.3 1.0 GO:0061144 alveolar secondary septum development(GO:0061144)
0.3 1.4 GO:0032275 luteinizing hormone secretion(GO:0032275) positive regulation of gonadotropin secretion(GO:0032278)
0.2 0.6 GO:0042536 negative regulation of tumor necrosis factor biosynthetic process(GO:0042536)
0.2 0.3 GO:0035482 gastric motility(GO:0035482) gastric emptying(GO:0035483)
0.1 0.6 GO:0050748 negative regulation of lipoprotein metabolic process(GO:0050748)
0.1 0.7 GO:0072757 cellular response to camptothecin(GO:0072757)
0.1 0.6 GO:0015692 vanadium ion transport(GO:0015676) lead ion transport(GO:0015692)
0.1 0.4 GO:0044861 protein transport into plasma membrane raft(GO:0044861)
0.1 0.6 GO:1900028 negative regulation of ruffle assembly(GO:1900028)
0.1 0.5 GO:1904659 glucose transmembrane transport(GO:1904659)
0.1 0.2 GO:1904956 regulation of endodermal cell fate specification(GO:0042663) regulation of canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment(GO:1901295) positive regulation of heart induction(GO:1901321) regulation of midbrain dopaminergic neuron differentiation(GO:1904956) regulation of canonical Wnt signaling pathway involved in heart development(GO:1905066)
0.1 0.3 GO:0044830 modulation by host of viral RNA genome replication(GO:0044830)
0.1 1.0 GO:0097034 mitochondrial respiratory chain complex IV assembly(GO:0033617) mitochondrial respiratory chain complex IV biogenesis(GO:0097034)
0.1 0.2 GO:0021691 cerebellar Purkinje cell layer maturation(GO:0021691)
0.1 0.4 GO:1901525 negative regulation of macromitophagy(GO:1901525)
0.1 0.2 GO:0032382 positive regulation of intracellular lipid transport(GO:0032379) positive regulation of intracellular sterol transport(GO:0032382) positive regulation of intracellular cholesterol transport(GO:0032385) lipid hydroperoxide transport(GO:1901373)
0.1 0.2 GO:0007217 tachykinin receptor signaling pathway(GO:0007217)
0.1 2.2 GO:0006805 xenobiotic metabolic process(GO:0006805)
0.0 0.1 GO:0097274 urea homeostasis(GO:0097274)
0.0 0.2 GO:0034196 acylglycerol transport(GO:0034196) triglyceride transport(GO:0034197)
0.0 0.6 GO:0010225 response to UV-C(GO:0010225)
0.0 0.2 GO:1900220 semaphorin-plexin signaling pathway involved in bone trabecula morphogenesis(GO:1900220)
0.0 0.1 GO:0052695 cellular glucuronidation(GO:0052695)
0.0 0.1 GO:0000957 mitochondrial RNA catabolic process(GO:0000957) regulation of mitochondrial RNA catabolic process(GO:0000960)
0.0 0.3 GO:0006682 galactosylceramide biosynthetic process(GO:0006682) galactolipid biosynthetic process(GO:0019375)
0.0 0.1 GO:0060737 prostate epithelial cord elongation(GO:0060523) prostate gland morphogenetic growth(GO:0060737)
0.0 0.3 GO:0018095 protein polyglutamylation(GO:0018095)
0.0 0.1 GO:1903347 negative regulation of bicellular tight junction assembly(GO:1903347)
0.0 0.4 GO:0043252 sodium-independent organic anion transport(GO:0043252)
0.0 0.1 GO:0034436 glycoprotein transport(GO:0034436)
0.0 0.2 GO:0032782 bile acid secretion(GO:0032782)
0.0 0.1 GO:0015705 iodide transport(GO:0015705)
0.0 0.2 GO:0006104 succinyl-CoA metabolic process(GO:0006104)
0.0 2.8 GO:0060349 bone morphogenesis(GO:0060349)
0.0 0.6 GO:2000651 positive regulation of sodium ion transmembrane transporter activity(GO:2000651)
0.0 0.1 GO:2000857 positive regulation of mineralocorticoid secretion(GO:2000857) positive regulation of aldosterone secretion(GO:2000860)
0.0 1.0 GO:0072698 protein localization to microtubule cytoskeleton(GO:0072698)
0.0 0.1 GO:1904884 telomerase catalytic core complex assembly(GO:1904868) regulation of telomerase catalytic core complex assembly(GO:1904882) positive regulation of telomerase catalytic core complex assembly(GO:1904884)
0.0 0.1 GO:0090400 stress-induced premature senescence(GO:0090400)
0.0 0.1 GO:0090070 positive regulation of ribosome biogenesis(GO:0090070) positive regulation of rRNA processing(GO:2000234)
0.0 0.3 GO:0098743 cartilage condensation(GO:0001502) cell aggregation(GO:0098743)
0.0 0.2 GO:0006817 phosphate ion transport(GO:0006817)
0.0 0.1 GO:0018401 peptidyl-proline hydroxylation to 4-hydroxy-L-proline(GO:0018401)
0.0 0.9 GO:0010718 positive regulation of epithelial to mesenchymal transition(GO:0010718)
0.0 0.0 GO:0015886 heme transport(GO:0015886)
0.0 0.1 GO:0006659 phosphatidylserine biosynthetic process(GO:0006659)
0.0 0.4 GO:0007608 sensory perception of smell(GO:0007608)
0.0 0.2 GO:0090110 cargo loading into COPII-coated vesicle(GO:0090110)
0.0 0.1 GO:0042989 sequestering of actin monomers(GO:0042989)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.6 GO:0034365 discoidal high-density lipoprotein particle(GO:0034365)
0.1 0.6 GO:0070826 paraferritin complex(GO:0070826)
0.1 0.4 GO:0044352 pinosome(GO:0044352) macropinosome(GO:0044354)
0.1 1.0 GO:0097431 mitotic spindle pole(GO:0097431)
0.0 0.2 GO:0030062 mitochondrial tricarboxylic acid cycle enzyme complex(GO:0030062)
0.0 0.2 GO:0031315 extrinsic component of mitochondrial outer membrane(GO:0031315)
0.0 0.6 GO:0010369 chromocenter(GO:0010369)
0.0 0.1 GO:0034361 very-low-density lipoprotein particle(GO:0034361) triglyceride-rich lipoprotein particle(GO:0034385)
0.0 0.1 GO:0061689 tricellular tight junction(GO:0061689)
0.0 1.0 GO:0005758 mitochondrial intermembrane space(GO:0005758)
0.0 0.2 GO:0030126 COPI vesicle coat(GO:0030126)
0.0 0.1 GO:0097550 transcriptional preinitiation complex(GO:0097550)
0.0 0.2 GO:0031528 microvillus membrane(GO:0031528)
0.0 0.6 GO:0030027 lamellipodium(GO:0030027)
0.0 0.1 GO:0030688 preribosome, small subunit precursor(GO:0030688)
0.0 0.2 GO:0030127 COPII vesicle coat(GO:0030127)
0.0 0.1 GO:0035631 IkappaB kinase complex(GO:0008385) CD40 receptor complex(GO:0035631)
0.0 0.1 GO:0000220 vacuolar proton-transporting V-type ATPase, V0 domain(GO:0000220)
0.0 1.2 GO:0005814 centriole(GO:0005814)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.0 GO:0005007 fibroblast growth factor-activated receptor activity(GO:0005007)
0.1 0.6 GO:0015086 cadmium ion transmembrane transporter activity(GO:0015086) lead ion transmembrane transporter activity(GO:0015094) vanadium ion transmembrane transporter activity(GO:0015100) ferrous iron uptake transmembrane transporter activity(GO:0015639)
0.1 1.7 GO:0004033 aldo-keto reductase (NADP) activity(GO:0004033)
0.1 0.2 GO:0004774 succinate-CoA ligase activity(GO:0004774)
0.1 0.2 GO:0048019 receptor antagonist activity(GO:0048019)
0.1 0.3 GO:0001733 galactosylceramide sulfotransferase activity(GO:0001733)
0.1 0.4 GO:0004984 olfactory receptor activity(GO:0004984)
0.1 1.4 GO:0071855 neuropeptide receptor binding(GO:0071855)
0.1 1.9 GO:0017147 Wnt-protein binding(GO:0017147)
0.1 0.2 GO:0050632 propanoyl-CoA C-acyltransferase activity(GO:0033814) propionyl-CoA C2-trimethyltridecanoyltransferase activity(GO:0050632) phosphatidylethanolamine transporter activity(GO:1904121)
0.1 0.2 GO:0000832 inositol hexakisphosphate kinase activity(GO:0000828) inositol hexakisphosphate 5-kinase activity(GO:0000832) inositol hexakisphosphate 1-kinase activity(GO:0052723) inositol hexakisphosphate 3-kinase activity(GO:0052724)
0.1 0.2 GO:0004703 G-protein coupled receptor kinase activity(GO:0004703)
0.0 0.1 GO:0005128 erythropoietin receptor binding(GO:0005128)
0.0 0.6 GO:0005522 profilin binding(GO:0005522)
0.0 0.1 GO:0008384 IkappaB kinase activity(GO:0008384)
0.0 0.1 GO:0034437 glycoprotein transporter activity(GO:0034437)
0.0 3.1 GO:0070491 repressing transcription factor binding(GO:0070491)
0.0 0.4 GO:0015347 sodium-independent organic anion transmembrane transporter activity(GO:0015347)
0.0 0.1 GO:0015111 iodide transmembrane transporter activity(GO:0015111)
0.0 2.8 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.0 0.3 GO:0070739 protein-glutamic acid ligase activity(GO:0070739)
0.0 0.1 GO:0031798 type 1 metabotropic glutamate receptor binding(GO:0031798) RNA polymerase II transcription factor activity, estrogen-activated sequence-specific DNA binding(GO:0038052)
0.0 0.4 GO:0005355 glucose transmembrane transporter activity(GO:0005355)
0.0 0.5 GO:0070402 NADPH binding(GO:0070402)
0.0 0.1 GO:0015254 glycerol channel activity(GO:0015254)
0.0 0.4 GO:0051010 microtubule plus-end binding(GO:0051010)
0.0 0.1 GO:0032767 copper-dependent protein binding(GO:0032767)
0.0 0.6 GO:0097602 cullin family protein binding(GO:0097602)
0.0 0.0 GO:0001226 RNA polymerase II transcription corepressor binding(GO:0001226)
0.0 0.0 GO:0015232 heme transporter activity(GO:0015232)
0.0 0.1 GO:0031545 peptidyl-proline 4-dioxygenase activity(GO:0031545)
0.0 0.3 GO:0042165 neurotransmitter binding(GO:0042165)
0.0 0.2 GO:0008331 high voltage-gated calcium channel activity(GO:0008331)
0.0 1.0 GO:0019894 kinesin binding(GO:0019894)
0.0 0.1 GO:0032405 MutLalpha complex binding(GO:0032405) MutSalpha complex binding(GO:0032407)
0.0 0.2 GO:0017154 semaphorin receptor activity(GO:0017154)
0.0 0.1 GO:0009931 calcium-dependent protein serine/threonine kinase activity(GO:0009931)
0.0 0.2 GO:0005537 mannose binding(GO:0005537)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 2.2 PID_WNT_SIGNALING_PATHWAY Wnt signaling network
0.1 2.6 PID_NFAT_TFPATHWAY Calcineurin-regulated NFAT-dependent transcription in lymphocytes
0.0 2.9 NABA_ECM_REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.0 0.6 PID_HIF2PATHWAY HIF-2-alpha transcription factor network
0.0 1.0 PID_FGF_PATHWAY FGF signaling pathway
0.0 0.6 PID_LIS1_PATHWAY Lissencephaly gene (LIS1) in neuronal migration and development
0.0 0.6 PID_AURORA_B_PATHWAY Aurora B signaling

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 2.8 REACTOME_REGULATION_OF_INSULIN_LIKE_GROWTH_FACTOR_IGF_ACTIVITY_BY_INSULIN_LIKE_GROWTH_FACTOR_BINDING_PROTEINS_IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.1 1.0 REACTOME_FGFR4_LIGAND_BINDING_AND_ACTIVATION Genes involved in FGFR4 ligand binding and activation
0.0 0.6 REACTOME_GENERATION_OF_SECOND_MESSENGER_MOLECULES Genes involved in Generation of second messenger molecules
0.0 2.4 REACTOME_NOTCH1_INTRACELLULAR_DOMAIN_REGULATES_TRANSCRIPTION Genes involved in NOTCH1 Intracellular Domain Regulates Transcription
0.0 0.2 REACTOME_SYNTHESIS_OF_BILE_ACIDS_AND_BILE_SALTS_VIA_7ALPHA_HYDROXYCHOLESTEROL Genes involved in Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol
0.0 0.2 REACTOME_COPI_MEDIATED_TRANSPORT Genes involved in COPI Mediated Transport
0.0 0.1 REACTOME_NFKB_IS_ACTIVATED_AND_SIGNALS_SURVIVAL Genes involved in NF-kB is activated and signals survival
0.0 0.1 REACTOME_PASSIVE_TRANSPORT_BY_AQUAPORINS Genes involved in Passive Transport by Aquaporins
0.0 0.1 REACTOME_GLUCURONIDATION Genes involved in Glucuronidation
0.0 1.0 REACTOME_PEPTIDE_LIGAND_BINDING_RECEPTORS Genes involved in Peptide ligand-binding receptors
0.0 0.3 REACTOME_DCC_MEDIATED_ATTRACTIVE_SIGNALING Genes involved in DCC mediated attractive signaling
0.0 0.2 REACTOME_CITRIC_ACID_CYCLE_TCA_CYCLE Genes involved in Citric acid cycle (TCA cycle)