Motif ID: Hnf4a

Z-value: 0.816


Transcription factors associated with Hnf4a:

Gene SymbolEntrez IDGene Name
Hnf4a ENSMUSG00000017950.10 Hnf4a



Activity profile for motif Hnf4a.

activity profile for motif Hnf4a


Sorted Z-values histogram for motif Hnf4a

Sorted Z-values for motif Hnf4a



Network of associatons between targets according to the STRING database.



First level regulatory network of Hnf4a

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr14_+_101840602 5.918 ENSMUST00000159314.1
Lmo7
LIM domain only 7
chr14_+_101840501 5.393 ENSMUST00000159026.1
Lmo7
LIM domain only 7
chr15_+_3270767 5.080 ENSMUST00000082424.4
ENSMUST00000159158.1
ENSMUST00000159216.1
ENSMUST00000160311.1
Sepp1



selenoprotein P, plasma, 1



chr9_-_77347816 4.382 ENSMUST00000184138.1
ENSMUST00000184006.1
ENSMUST00000185144.1
ENSMUST00000034910.9
Mlip



muscular LMNA-interacting protein



chr16_-_22439719 4.071 ENSMUST00000079601.6
Etv5
ets variant gene 5
chr9_-_77347787 3.540 ENSMUST00000184848.1
ENSMUST00000184415.1
Mlip

muscular LMNA-interacting protein

chr7_+_45896941 3.536 ENSMUST00000069772.7
ENSMUST00000107716.1
Tmem143

transmembrane protein 143

chr2_-_131042682 3.282 ENSMUST00000028787.5
ENSMUST00000110239.1
ENSMUST00000110234.1
Gfra4


glial cell line derived neurotrophic factor family receptor alpha 4


chr7_+_112225856 3.031 ENSMUST00000050149.5
ENSMUST00000106647.1
ENSMUST00000106648.1
Mical2


microtubule associated monooxygenase, calponin and LIM domain containing 2


chr11_-_81968415 2.913 ENSMUST00000066197.6
Asic2
acid-sensing (proton-gated) ion channel 2
chr2_-_131043088 2.902 ENSMUST00000110240.3
ENSMUST00000066958.4
ENSMUST00000110235.1
Gfra4


glial cell line derived neurotrophic factor family receptor alpha 4


chr11_+_104282371 2.845 ENSMUST00000106988.1
ENSMUST00000106989.1
Mapt

microtubule-associated protein tau

chr4_+_136286061 2.541 ENSMUST00000069195.4
ENSMUST00000130658.1
Zfp46

zinc finger protein 46

chrX_-_162565514 2.493 ENSMUST00000154424.1
Reps2
RALBP1 associated Eps domain containing protein 2
chr15_+_82252397 2.463 ENSMUST00000136948.1
1500009C09Rik
RIKEN cDNA 1500009C09 gene
chr7_+_45897429 2.365 ENSMUST00000140243.1
Tmem143
transmembrane protein 143
chr8_-_113848615 2.096 ENSMUST00000093113.4
Adamts18
a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 18
chr8_-_13200576 1.982 ENSMUST00000165605.2
Grtp1
GH regulated TBC protein 1
chr11_+_78499087 1.951 ENSMUST00000017488.4
Vtn
vitronectin
chr7_+_25268387 1.879 ENSMUST00000169392.1
Cic
capicua homolog (Drosophila)
chr17_+_55445375 1.849 ENSMUST00000133899.1
ENSMUST00000086878.3
St6gal2

beta galactoside alpha 2,6 sialyltransferase 2

chr2_+_59160838 1.834 ENSMUST00000102754.4
ENSMUST00000168631.1
ENSMUST00000123908.1
Pkp4


plakophilin 4


chr6_+_86195214 1.750 ENSMUST00000032066.9
Tgfa
transforming growth factor alpha
chrX_+_6415736 1.685 ENSMUST00000143641.3
Shroom4
shroom family member 4
chr4_-_119538769 1.685 ENSMUST00000079611.6
AA415398
expressed sequence AA415398
chr2_+_130406478 1.650 ENSMUST00000055421.4
Tmem239
transmembrane 239
chr6_+_54429603 1.598 ENSMUST00000132855.1
ENSMUST00000126637.1
Wipf3

WAS/WASL interacting protein family, member 3

chr10_-_13552838 1.569 ENSMUST00000105541.1
Pex3
peroxisomal biogenesis factor 3
chr4_+_126609818 1.561 ENSMUST00000097886.3
ENSMUST00000164362.1
5730409E04Rik

RIKEN cDNA 5730409E04Rik gene

chr8_+_84990585 1.547 ENSMUST00000064495.6
Hook2
hook homolog 2 (Drosophila)
chr5_+_19907774 1.525 ENSMUST00000115267.2
Magi2
membrane associated guanylate kinase, WW and PDZ domain containing 2
chr7_+_67222544 1.524 ENSMUST00000058771.5
ENSMUST00000179106.1
Lysmd4

LysM, putative peptidoglycan-binding, domain containing 4

chr6_+_85431970 1.477 ENSMUST00000045693.7
Smyd5
SET and MYND domain containing 5
chr2_-_59160644 1.456 ENSMUST00000077687.5
Ccdc148
coiled-coil domain containing 148
chr9_+_58582240 1.414 ENSMUST00000177292.1
ENSMUST00000085651.5
Nptn

neuroplastin

chr6_-_86765807 1.368 ENSMUST00000123732.1
Anxa4
annexin A4
chr8_-_83594440 1.366 ENSMUST00000019382.9
ENSMUST00000165740.1
Tecr

trans-2,3-enoyl-CoA reductase

chr5_-_24447587 1.356 ENSMUST00000127194.1
ENSMUST00000115033.1
ENSMUST00000123167.1
ENSMUST00000030799.8
Tmub1



transmembrane and ubiquitin-like domain containing 1



chr4_+_152199805 1.352 ENSMUST00000105652.2
Acot7
acyl-CoA thioesterase 7
chr1_-_155417394 1.339 ENSMUST00000111775.1
ENSMUST00000111774.1
Xpr1

xenotropic and polytropic retrovirus receptor 1

chr5_+_19907502 1.316 ENSMUST00000101558.3
Magi2
membrane associated guanylate kinase, WW and PDZ domain containing 2
chr8_-_83594405 1.269 ENSMUST00000163837.1
Tecr
trans-2,3-enoyl-CoA reductase
chr19_+_44992127 1.268 ENSMUST00000179305.1
Sema4g
sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4G
chr16_-_34513944 1.261 ENSMUST00000151491.1
ENSMUST00000114960.2
Kalrn

kalirin, RhoGEF kinase

chr2_+_92375306 1.243 ENSMUST00000028650.8
Pex16
peroxisomal biogenesis factor 16
chr3_+_107877227 1.230 ENSMUST00000037375.8
Eps8l3
EPS8-like 3
chr12_+_51593315 1.225 ENSMUST00000164782.2
ENSMUST00000085412.5
Coch

coagulation factor C homolog (Limulus polyphemus)

chr9_-_44288332 1.212 ENSMUST00000161408.1
Abcg4
ATP-binding cassette, sub-family G (WHITE), member 4
chr16_-_34514084 1.199 ENSMUST00000089655.5
Kalrn
kalirin, RhoGEF kinase
chr1_+_132008285 1.186 ENSMUST00000146432.1
Elk4
ELK4, member of ETS oncogene family
chr17_-_91088726 1.173 ENSMUST00000072671.7
ENSMUST00000174331.1
ENSMUST00000161402.3
ENSMUST00000054059.8
Nrxn1



neurexin I



chr15_-_102722120 1.166 ENSMUST00000171838.1
Calcoco1
calcium binding and coiled coil domain 1
chr2_+_3704787 1.134 ENSMUST00000115054.2
Fam107b
family with sequence similarity 107, member B
chr19_-_45998479 1.121 ENSMUST00000045396.7
9130011E15Rik
RIKEN cDNA 9130011E15 gene
chr9_-_44288535 1.059 ENSMUST00000161354.1
Abcg4
ATP-binding cassette, sub-family G (WHITE), member 4
chr7_+_28833975 1.045 ENSMUST00000066723.8
Lgals4
lectin, galactose binding, soluble 4
chr10_+_70204675 1.039 ENSMUST00000020090.1
2310015B20Rik
RIKEN cDNA 2310015B20 gene
chr6_-_86765866 1.039 ENSMUST00000113675.1
Anxa4
annexin A4
chr17_-_45592569 1.031 ENSMUST00000163492.1
Slc29a1
solute carrier family 29 (nucleoside transporters), member 1
chr5_-_125294107 1.018 ENSMUST00000127148.1
Scarb1
scavenger receptor class B, member 1
chr4_+_120854786 1.016 ENSMUST00000071093.2
Rims3
regulating synaptic membrane exocytosis 3
chrX_-_95166307 1.005 ENSMUST00000113873.2
ENSMUST00000113876.2
ENSMUST00000113885.1
ENSMUST00000113883.1
ENSMUST00000182001.1
ENSMUST00000113882.1
ENSMUST00000113878.1
ENSMUST00000182562.1
Arhgef9







CDC42 guanine nucleotide exchange factor (GEF) 9







chrX_-_73660047 0.991 ENSMUST00000114472.1
Pnck
pregnancy upregulated non-ubiquitously expressed CaM kinase
chr13_-_41273977 0.988 ENSMUST00000163881.1
Gm17364
predicted gene, 17364
chr19_+_46356880 0.986 ENSMUST00000086969.6
ENSMUST00000128455.1
Tmem180

transmembrane protein 180

chr11_+_103774150 0.984 ENSMUST00000000127.5
Wnt3
wingless-related MMTV integration site 3
chr6_+_125145235 0.963 ENSMUST00000119527.1
ENSMUST00000088276.6
ENSMUST00000051171.7
ENSMUST00000117675.1
Iffo1



intermediate filament family orphan 1



chr2_-_130638094 0.953 ENSMUST00000089561.3
ENSMUST00000110260.1
Lzts3

leucine zipper, putative tumor suppressor family member 3

chr15_-_102722150 0.947 ENSMUST00000023818.3
Calcoco1
calcium binding and coiled coil domain 1
chr13_+_67833235 0.942 ENSMUST00000060609.7
Gm10037
predicted gene 10037
chr12_-_67222549 0.904 ENSMUST00000037181.8
Mdga2
MAM domain containing glycosylphosphatidylinositol anchor 2
chr11_+_4986824 0.865 ENSMUST00000009234.9
ENSMUST00000109897.1
Ap1b1

adaptor protein complex AP-1, beta 1 subunit

chr12_-_79192248 0.862 ENSMUST00000161204.1
Rdh11
retinol dehydrogenase 11
chr5_+_30232581 0.846 ENSMUST00000145167.1
Ept1
ethanolaminephosphotransferase 1 (CDP-ethanolamine-specific)
chr11_+_22512088 0.843 ENSMUST00000059319.7
Tmem17
transmembrane protein 17
chr3_-_104818539 0.841 ENSMUST00000106774.1
ENSMUST00000106775.1
ENSMUST00000166979.1
ENSMUST00000136148.1
Mov10



Moloney leukemia virus 10



chr17_-_45592485 0.834 ENSMUST00000166119.1
Slc29a1
solute carrier family 29 (nucleoside transporters), member 1
chr3_-_84305385 0.829 ENSMUST00000122849.1
ENSMUST00000132283.1
Trim2

tripartite motif-containing 2

chr12_+_58211772 0.825 ENSMUST00000110671.2
ENSMUST00000044299.2
Sstr1

somatostatin receptor 1

chr17_-_45592262 0.816 ENSMUST00000164769.1
Slc29a1
solute carrier family 29 (nucleoside transporters), member 1
chrX_-_73659724 0.814 ENSMUST00000114473.1
ENSMUST00000002087.7
Pnck

pregnancy upregulated non-ubiquitously expressed CaM kinase

chr7_+_66689889 0.806 ENSMUST00000153007.1
ENSMUST00000177726.1
ENSMUST00000121777.2
ENSMUST00000150071.1
ENSMUST00000077967.6
Lins




lines homolog (Drosophila)




chr15_+_12117848 0.801 ENSMUST00000128475.1
ENSMUST00000134277.1
Zfr

zinc finger RNA binding protein

chr11_+_105967938 0.792 ENSMUST00000001963.7
Ace
angiotensin I converting enzyme (peptidyl-dipeptidase A) 1
chr6_+_124663027 0.768 ENSMUST00000004381.7
Lpcat3
lysophosphatidylcholine acyltransferase 3
chr3_-_108085346 0.767 ENSMUST00000078912.5
Ampd2
adenosine monophosphate deaminase 2
chr4_+_94739276 0.751 ENSMUST00000073939.6
ENSMUST00000102798.1
Tek

endothelial-specific receptor tyrosine kinase

chr3_-_121815212 0.749 ENSMUST00000029770.5
Abcd3
ATP-binding cassette, sub-family D (ALD), member 3
chr7_+_46847128 0.733 ENSMUST00000005051.4
Ldha
lactate dehydrogenase A
chr3_-_109027600 0.732 ENSMUST00000171143.1
Fam102b
family with sequence similarity 102, member B
chr5_+_117120120 0.712 ENSMUST00000111978.1
Taok3
TAO kinase 3
chrX_-_105929333 0.709 ENSMUST00000134507.1
ENSMUST00000137453.1
ENSMUST00000150914.1
Atrx


alpha thalassemia/mental retardation syndrome X-linked homolog (human)


chr11_-_101987004 0.691 ENSMUST00000107173.2
ENSMUST00000107172.1
Dusp3

dual specificity phosphatase 3 (vaccinia virus phosphatase VH1-related)

chrX_-_150814265 0.657 ENSMUST00000026302.6
ENSMUST00000129768.1
ENSMUST00000112699.2
Maged2


melanoma antigen, family D, 2


chr17_-_35909626 0.657 ENSMUST00000141132.1
Atat1
alpha tubulin acetyltransferase 1
chrX_-_105929206 0.646 ENSMUST00000134381.1
ENSMUST00000154866.1
Atrx

alpha thalassemia/mental retardation syndrome X-linked homolog (human)

chr4_-_42084291 0.623 ENSMUST00000177937.1
Gm21968
predicted gene, 21968
chr3_+_96830069 0.614 ENSMUST00000058865.7
Pdzk1
PDZ domain containing 1
chr5_+_31698050 0.601 ENSMUST00000114507.3
ENSMUST00000063813.4
ENSMUST00000071531.5
ENSMUST00000131995.1
Bre



brain and reproductive organ-expressed protein



chr15_-_100424208 0.600 ENSMUST00000154331.1
Slc11a2
solute carrier family 11 (proton-coupled divalent metal ion transporters), member 2
chr1_-_155417283 0.599 ENSMUST00000027741.5
Xpr1
xenotropic and polytropic retrovirus receptor 1
chr14_-_41006882 0.592 ENSMUST00000152837.1
ENSMUST00000134715.1
Fam213a

family with sequence similarity 213, member A

chr9_+_22003035 0.590 ENSMUST00000115331.2
ENSMUST00000003493.7
Prkcsh

protein kinase C substrate 80K-H

chr19_-_44407703 0.584 ENSMUST00000041331.2
Scd1
stearoyl-Coenzyme A desaturase 1
chr6_-_85137743 0.575 ENSMUST00000174769.1
ENSMUST00000174286.1
ENSMUST00000045986.7
Spr


sepiapterin reductase


chr17_+_34604262 0.564 ENSMUST00000174041.1
Agpat1
1-acylglycerol-3-phosphate O-acyltransferase 1 (lysophosphatidic acid acyltransferase, alpha)
chr5_+_31697960 0.551 ENSMUST00000114515.2
Bre
brain and reproductive organ-expressed protein
chr15_-_27630644 0.550 ENSMUST00000059662.7
Fam105b
family with sequence similarity 105, member B
chr17_-_28486082 0.548 ENSMUST00000079413.3
Fkbp5
FK506 binding protein 5
chr7_+_30232032 0.540 ENSMUST00000149654.1
Polr2i
polymerase (RNA) II (DNA directed) polypeptide I
chr7_-_67222412 0.540 ENSMUST00000181631.1
1700112J16Rik
RIKEN cDNA 1700112J16 gene
chr2_+_71117923 0.535 ENSMUST00000028403.2
Cybrd1
cytochrome b reductase 1
chr9_-_57147034 0.505 ENSMUST00000034842.4
Neil1
nei endonuclease VIII-like 1 (E. coli)
chr17_-_35910032 0.497 ENSMUST00000141662.1
ENSMUST00000056034.6
ENSMUST00000077494.6
ENSMUST00000149277.1
ENSMUST00000061052.5
Atat1




alpha tubulin acetyltransferase 1




chr1_+_172499948 0.492 ENSMUST00000111230.1
Tagln2
transgelin 2
chr12_+_111678094 0.488 ENSMUST00000084947.3
ENSMUST00000168338.1
Trmt61a

tRNA methyltransferase 61A

chr2_+_91096744 0.473 ENSMUST00000132741.2
Spi1
spleen focus forming virus (SFFV) proviral integration oncogene
chr3_-_84304762 0.459 ENSMUST00000107692.1
Trim2
tripartite motif-containing 2
chr7_-_110614761 0.427 ENSMUST00000166020.1
ENSMUST00000171218.1
ENSMUST00000033058.7
ENSMUST00000164759.1
Sbf2



SET binding factor 2



chr1_+_85894281 0.426 ENSMUST00000027425.9
Itm2c
integral membrane protein 2C
chr10_+_13552894 0.426 ENSMUST00000019944.8
Adat2
adenosine deaminase, tRNA-specific 2
chr11_-_8664499 0.420 ENSMUST00000020695.6
Tns3
tensin 3
chr3_-_67463828 0.404 ENSMUST00000058981.2
Lxn
latexin
chr17_-_35667546 0.401 ENSMUST00000043674.8
Vars2
valyl-tRNA synthetase 2, mitochondrial (putative)
chr8_-_41016295 0.381 ENSMUST00000131965.1
Mtus1
mitochondrial tumor suppressor 1
chr5_-_66514815 0.377 ENSMUST00000161879.1
ENSMUST00000159357.1
Apbb2

amyloid beta (A4) precursor protein-binding, family B, member 2

chr4_-_118409219 0.377 ENSMUST00000075406.5
Szt2
seizure threshold 2
chr1_+_63176818 0.374 ENSMUST00000129339.1
Eef1b2
eukaryotic translation elongation factor 1 beta 2
chr2_+_158028733 0.371 ENSMUST00000152452.1
Rprd1b
regulation of nuclear pre-mRNA domain containing 1B
chr6_-_83156393 0.356 ENSMUST00000153148.1
ENSMUST00000125894.1
Wdr54

WD repeat domain 54

chr19_+_44203265 0.356 ENSMUST00000026220.5
Scd3
stearoyl-coenzyme A desaturase 3
chr18_-_79109391 0.344 ENSMUST00000025430.8
ENSMUST00000161465.2
Setbp1

SET binding protein 1

chr11_-_120990871 0.332 ENSMUST00000154483.1
Csnk1d
casein kinase 1, delta
chr11_+_3895223 0.315 ENSMUST00000055931.4
ENSMUST00000109996.1
Dusp18

dual specificity phosphatase 18

chr3_-_130730375 0.315 ENSMUST00000079085.6
Rpl34
ribosomal protein L34
chr16_-_34095983 0.308 ENSMUST00000114973.1
ENSMUST00000114964.1
Kalrn

kalirin, RhoGEF kinase

chr2_+_112239468 0.305 ENSMUST00000028554.3
Lpcat4
lysophosphatidylcholine acyltransferase 4
chr5_+_31697665 0.294 ENSMUST00000080598.7
Bre
brain and reproductive organ-expressed protein
chr7_+_30232310 0.275 ENSMUST00000108193.1
ENSMUST00000108192.1
Polr2i

polymerase (RNA) II (DNA directed) polypeptide I

chr1_+_171213969 0.268 ENSMUST00000005820.4
ENSMUST00000075469.5
ENSMUST00000155126.1
Nr1i3


nuclear receptor subfamily 1, group I, member 3


chr6_-_122602345 0.266 ENSMUST00000147760.1
ENSMUST00000112585.1
Apobec1

apolipoprotein B mRNA editing enzyme, catalytic polypeptide 1

chr2_-_158028423 0.265 ENSMUST00000029179.4
Tti1
TELO2 interacting protein 1
chr6_+_113282302 0.265 ENSMUST00000041203.5
Cpne9
copine family member IX
chr16_+_14580221 0.251 ENSMUST00000147024.1
A630010A05Rik
RIKEN cDNA A630010A05 gene
chr3_+_95134088 0.250 ENSMUST00000066386.5
Lysmd1
LysM, putative peptidoglycan-binding, domain containing 1
chr10_-_128744014 0.247 ENSMUST00000026414.7
Dgka
diacylglycerol kinase, alpha
chr16_-_17928136 0.245 ENSMUST00000003622.8
Slc25a1
solute carrier family 25 (mitochondrial carrier, citrate transporter), member 1
chr3_-_130730310 0.240 ENSMUST00000062601.7
Rpl34
ribosomal protein L34
chr16_-_4624984 0.236 ENSMUST00000014445.6
Pam16
presequence translocase-asssociated motor 16 homolog (S. cerevisiae)
chr7_+_27452417 0.235 ENSMUST00000108357.1
Blvrb
biliverdin reductase B (flavin reductase (NADPH))
chr11_+_58199556 0.234 ENSMUST00000058704.8
ENSMUST00000035266.4
ENSMUST00000094169.4
ENSMUST00000168280.1
Irgm2
Igtp


immunity-related GTPase family M member 2
interferon gamma induced GTPase


chr3_-_107696462 0.227 ENSMUST00000029490.8
Ahcyl1
S-adenosylhomocysteine hydrolase-like 1
chr7_-_28598140 0.220 ENSMUST00000108283.1
ENSMUST00000040531.8
Pak4
Samd4b
p21 protein (Cdc42/Rac)-activated kinase 4
sterile alpha motif domain containing 4B
chr1_-_77515048 0.210 ENSMUST00000027451.6
Epha4
Eph receptor A4
chr4_-_138326234 0.207 ENSMUST00000105817.3
ENSMUST00000030536.6
Pink1

PTEN induced putative kinase 1

chr1_+_12718496 0.199 ENSMUST00000088585.3
Sulf1
sulfatase 1
chr9_-_78480736 0.198 ENSMUST00000156988.1
Eef1a1
eukaryotic translation elongation factor 1 alpha 1
chrX_-_105929397 0.198 ENSMUST00000113573.1
ENSMUST00000130980.1
Atrx

alpha thalassemia/mental retardation syndrome X-linked homolog (human)

chr11_-_3504766 0.195 ENSMUST00000044507.5
Inpp5j
inositol polyphosphate 5-phosphatase J
chr3_+_89136572 0.194 ENSMUST00000107482.3
ENSMUST00000127058.1
Pklr

pyruvate kinase liver and red blood cell

chr18_+_63708689 0.194 ENSMUST00000072726.5
Wdr7
WD repeat domain 7
chr7_+_28392916 0.190 ENSMUST00000003529.8
Paf1
Paf1, RNA polymerase II associated factor, homolog (S. cerevisiae)
chr18_+_36348653 0.178 ENSMUST00000050584.3
Cystm1
cysteine-rich transmembrane module containing 1
chr11_-_61267177 0.171 ENSMUST00000066277.3
ENSMUST00000074127.7
ENSMUST00000108715.2
Aldh3a2


aldehyde dehydrogenase family 3, subfamily A2


chr8_+_12915879 0.164 ENSMUST00000110876.2
ENSMUST00000110879.2
Mcf2l

mcf.2 transforming sequence-like

chr11_-_86757483 0.156 ENSMUST00000060766.9
ENSMUST00000103186.4
Cltc

clathrin, heavy polypeptide (Hc)

chr10_-_60752773 0.152 ENSMUST00000117513.1
ENSMUST00000119595.1
Slc29a3

solute carrier family 29 (nucleoside transporters), member 3

chr6_+_21985903 0.145 ENSMUST00000137437.1
ENSMUST00000115383.2
Cped1

cadherin-like and PC-esterase domain containing 1

chr11_-_23519181 0.145 ENSMUST00000020527.5
1700093K21Rik
RIKEN cDNA 1700093K21 gene
chr6_+_86365673 0.140 ENSMUST00000071492.7
Fam136a
family with sequence similarity 136, member A
chr2_-_27248335 0.123 ENSMUST00000139312.1
Sardh
sarcosine dehydrogenase
chr19_-_10604258 0.123 ENSMUST00000037678.6
Dak
dihydroxyacetone kinase 2 homolog (yeast)
chr15_-_100424092 0.116 ENSMUST00000154676.1
Slc11a2
solute carrier family 11 (proton-coupled divalent metal ion transporters), member 2
chr2_-_77170592 0.106 ENSMUST00000164114.2
ENSMUST00000049544.7
Ccdc141

coiled-coil domain containing 141

chr7_-_28392688 0.104 ENSMUST00000003536.8
Med29
mediator complex subunit 29
chr14_-_55758458 0.104 ENSMUST00000001497.7
Cideb
cell death-inducing DNA fragmentation factor, alpha subunit-like effector B
chr12_-_93929102 0.100 ENSMUST00000180321.1
Gm9726
predicted gene 9726
chr2_+_158028687 0.099 ENSMUST00000109518.1
ENSMUST00000029180.7
Rprd1b

regulation of nuclear pre-mRNA domain containing 1B

chr10_-_128547722 0.092 ENSMUST00000040572.3
Zc3h10
zinc finger CCCH type containing 10
chr17_-_36129425 0.087 ENSMUST00000046131.9
ENSMUST00000173322.1
ENSMUST00000172968.1
Gm7030


predicted gene 7030


chrX_+_48623737 0.086 ENSMUST00000114936.1
Slc25a14
solute carrier family 25 (mitochondrial carrier, brain), member 14
chr11_+_55213783 0.084 ENSMUST00000108867.1
Slc36a1
solute carrier family 36 (proton/amino acid symporter), member 1
chr19_+_46152505 0.072 ENSMUST00000026254.7
Gbf1
golgi-specific brefeldin A-resistance factor 1
chr1_+_37872206 0.071 ENSMUST00000041621.3
Lipt1
lipoyltransferase 1
chr11_-_4704334 0.070 ENSMUST00000058407.5
Uqcr10
ubiquinol-cytochrome c reductase, complex III subunit X
chr16_+_18877037 0.063 ENSMUST00000120532.1
ENSMUST00000004222.7
Hira

histone cell cycle regulation defective homolog A (S. cerevisiae)

chr6_+_28475101 0.061 ENSMUST00000168362.1
Snd1
staphylococcal nuclease and tudor domain containing 1
chr1_-_63176653 0.059 ENSMUST00000027111.8
ENSMUST00000168099.2
Ndufs1

NADH dehydrogenase (ubiquinone) Fe-S protein 1

chr6_-_122602404 0.054 ENSMUST00000112586.1
Apobec1
apolipoprotein B mRNA editing enzyme, catalytic polypeptide 1
chr11_+_70970181 0.053 ENSMUST00000018593.3
Rpain
RPA interacting protein
chr2_-_164804876 0.040 ENSMUST00000103094.4
ENSMUST00000017451.6
Acot8

acyl-CoA thioesterase 8

chr1_-_74284636 0.040 ENSMUST00000178235.1
ENSMUST00000006462.7
Aamp

angio-associated migratory protein

chr1_+_37872333 0.033 ENSMUST00000142670.1
Lipt1
lipoyltransferase 1
chr1_+_74284930 0.032 ENSMUST00000113805.1
ENSMUST00000027370.6
ENSMUST00000087226.4
Pnkd


paroxysmal nonkinesiogenic dyskinesia


chr2_+_25500750 0.031 ENSMUST00000015239.3
Fbxw5
F-box and WD-40 domain protein 5
chr6_-_41636389 0.018 ENSMUST00000031902.5
Trpv6
transient receptor potential cation channel, subfamily V, member 6
chr2_+_158028481 0.017 ENSMUST00000103123.3
Rprd1b
regulation of nuclear pre-mRNA domain containing 1B
chr2_+_174760619 0.015 ENSMUST00000029030.2
Edn3
endothelin 3
chr8_-_40634750 0.013 ENSMUST00000173957.1
Mtmr7
myotubularin related protein 7
chr1_-_52190901 0.012 ENSMUST00000156887.1
ENSMUST00000129107.1
Gls

glutaminase


Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
1.0 2.9 GO:0050915 sensory perception of sour taste(GO:0050915)
0.8 4.1 GO:0048133 germ-line stem cell division(GO:0042078) male germ-line stem cell asymmetric division(GO:0048133) germline stem cell asymmetric division(GO:0098728)
0.6 3.0 GO:0010735 positive regulation of transcription via serum response element binding(GO:0010735)
0.5 4.0 GO:0097118 neuroligin clustering involved in postsynaptic membrane assembly(GO:0097118)
0.5 2.8 GO:0016557 peroxisome membrane biogenesis(GO:0016557)
0.4 2.4 GO:2000483 negative regulation of interleukin-8 secretion(GO:2000483)
0.4 1.6 GO:0097393 post-embryonic appendage morphogenesis(GO:0035120) post-embryonic limb morphogenesis(GO:0035127) post-embryonic forelimb morphogenesis(GO:0035128) telomeric repeat-containing RNA transcription(GO:0097393) telomeric repeat-containing RNA transcription from RNA pol II promoter(GO:0097394) regulation of telomeric RNA transcription from RNA pol II promoter(GO:1901580) negative regulation of telomeric RNA transcription from RNA pol II promoter(GO:1901581) positive regulation of telomeric RNA transcription from RNA pol II promoter(GO:1901582)
0.4 1.2 GO:0071929 alpha-tubulin acetylation(GO:0071929)
0.4 2.7 GO:0015862 uridine transport(GO:0015862)
0.3 2.8 GO:0061368 maternal process involved in parturition(GO:0060137) behavioral response to chemical pain(GO:0061366) behavioral response to formalin induced pain(GO:0061368)
0.3 1.0 GO:0015920 regulation of phosphatidylcholine catabolic process(GO:0010899) lipopolysaccharide transport(GO:0015920)
0.3 1.4 GO:1900533 medium-chain fatty-acyl-CoA catabolic process(GO:0036114) long-chain fatty-acyl-CoA catabolic process(GO:0036116) palmitic acid metabolic process(GO:1900533) palmitic acid biosynthetic process(GO:1900535)
0.3 1.0 GO:0044339 canonical Wnt signaling pathway involved in osteoblast differentiation(GO:0044339)
0.3 1.9 GO:0030643 cellular phosphate ion homeostasis(GO:0030643) phosphate ion transmembrane transport(GO:0035435) cellular trivalent inorganic anion homeostasis(GO:0072502)
0.3 2.8 GO:1900034 regulation of cellular response to heat(GO:1900034)
0.3 0.9 GO:0016056 rhodopsin mediated signaling pathway(GO:0016056)
0.3 1.4 GO:1902683 regulation of receptor localization to synapse(GO:1902683)
0.3 0.8 GO:0001193 maintenance of transcriptional fidelity during DNA-templated transcription elongation(GO:0001192) maintenance of transcriptional fidelity during DNA-templated transcription elongation from RNA polymerase II promoter(GO:0001193)
0.3 0.8 GO:2000170 positive regulation of peptidyl-cysteine S-nitrosylation(GO:2000170)
0.3 0.8 GO:0048014 Tie signaling pathway(GO:0048014)
0.2 0.7 GO:0015910 peroxisomal long-chain fatty acid import(GO:0015910)
0.2 0.9 GO:1903966 monounsaturated fatty acid metabolic process(GO:1903964) monounsaturated fatty acid biosynthetic process(GO:1903966)
0.2 0.2 GO:0036482 neuron intrinsic apoptotic signaling pathway in response to hydrogen peroxide(GO:0036482) positive regulation of mitochondrial electron transport, NADH to ubiquinone(GO:1902958) regulation of hydrogen peroxide-induced neuron intrinsic apoptotic signaling pathway(GO:1903383) negative regulation of hydrogen peroxide-induced neuron intrinsic apoptotic signaling pathway(GO:1903384)
0.2 2.6 GO:0042761 very long-chain fatty acid biosynthetic process(GO:0042761)
0.2 7.9 GO:0010614 negative regulation of cardiac muscle hypertrophy(GO:0010614)
0.2 2.0 GO:0097421 liver regeneration(GO:0097421)
0.1 0.7 GO:0019659 fermentation(GO:0006113) lactate biosynthetic process from pyruvate(GO:0019244) glucose catabolic process to lactate(GO:0019659) glycolytic fermentation(GO:0019660) glucose catabolic process to lactate via pyruvate(GO:0019661)
0.1 0.6 GO:0006558 L-phenylalanine metabolic process(GO:0006558) erythrose 4-phosphate/phosphoenolpyruvate family amino acid metabolic process(GO:1902221)
0.1 0.7 GO:0015692 vanadium ion transport(GO:0015676) lead ion transport(GO:0015692)
0.1 1.8 GO:0045741 positive regulation of epidermal growth factor-activated receptor activity(GO:0045741)
0.1 1.7 GO:0090331 negative regulation of platelet aggregation(GO:0090331)
0.1 0.8 GO:0032264 IMP salvage(GO:0032264)
0.1 0.7 GO:0070294 renal sodium ion transport(GO:0003096) renal sodium ion absorption(GO:0070294)
0.1 0.3 GO:0016554 cytidine to uridine editing(GO:0016554)
0.1 0.4 GO:0006438 valyl-tRNA aminoacylation(GO:0006438)
0.1 0.2 GO:0014846 esophagus smooth muscle contraction(GO:0014846)
0.1 0.5 GO:0045347 negative regulation of MHC class II biosynthetic process(GO:0045347)
0.1 1.7 GO:0006054 N-acetylneuraminate metabolic process(GO:0006054)
0.1 0.6 GO:0015879 carnitine transport(GO:0015879)
0.1 1.2 GO:0070932 histone H3 deacetylation(GO:0070932)
0.1 0.2 GO:1900126 negative regulation of hyaluronan biosynthetic process(GO:1900126)
0.1 0.2 GO:0061762 CAMKK-AMPK signaling cascade(GO:0061762)
0.1 0.4 GO:1901668 regulation of superoxide dismutase activity(GO:1901668)
0.1 6.2 GO:0030279 negative regulation of ossification(GO:0030279)
0.1 0.4 GO:0042985 negative regulation of amyloid precursor protein biosynthetic process(GO:0042985)
0.1 0.2 GO:0097155 fasciculation of sensory neuron axon(GO:0097155)
0.1 0.5 GO:0032074 negative regulation of nuclease activity(GO:0032074)
0.1 0.5 GO:0070940 dephosphorylation of RNA polymerase II C-terminal domain(GO:0070940)
0.1 2.1 GO:0033344 cholesterol efflux(GO:0033344)
0.1 1.8 GO:0032467 positive regulation of cytokinesis(GO:0032467)
0.0 0.2 GO:0006842 tricarboxylic acid transport(GO:0006842) citrate transport(GO:0015746)
0.0 0.1 GO:1901052 sarcosine metabolic process(GO:1901052) sarcosine catabolic process(GO:1901053)
0.0 0.5 GO:0006654 phosphatidic acid biosynthetic process(GO:0006654)
0.0 0.2 GO:0042045 epithelial fluid transport(GO:0042045)
0.0 0.8 GO:0071392 cellular response to estradiol stimulus(GO:0071392)
0.0 1.5 GO:0008333 endosome to lysosome transport(GO:0008333)
0.0 0.7 GO:0007095 mitotic G2 DNA damage checkpoint(GO:0007095)
0.0 0.2 GO:0042167 porphyrin-containing compound catabolic process(GO:0006787) tetrapyrrole catabolic process(GO:0033015) heme catabolic process(GO:0042167) pigment catabolic process(GO:0046149)
0.0 0.8 GO:0006379 mRNA cleavage(GO:0006379)
0.0 0.9 GO:0048268 clathrin coat assembly(GO:0048268)
0.0 5.0 GO:0002244 hematopoietic progenitor cell differentiation(GO:0002244)
0.0 1.0 GO:2000300 regulation of synaptic vesicle exocytosis(GO:2000300)
0.0 1.0 GO:0035335 peptidyl-tyrosine dephosphorylation(GO:0035335)
0.0 2.0 GO:0031338 regulation of vesicle fusion(GO:0031338)
0.0 1.8 GO:0048286 lung alveolus development(GO:0048286)
0.0 0.6 GO:0006491 N-glycan processing(GO:0006491)
0.0 1.3 GO:0050919 negative chemotaxis(GO:0050919)
0.0 0.2 GO:0016584 nucleosome positioning(GO:0016584)
0.0 0.4 GO:0050965 detection of temperature stimulus involved in sensory perception(GO:0050961) detection of temperature stimulus involved in sensory perception of pain(GO:0050965)
0.0 0.4 GO:0002097 tRNA wobble base modification(GO:0002097)
0.0 0.2 GO:0046292 formaldehyde metabolic process(GO:0046292)
0.0 0.5 GO:0010039 response to iron ion(GO:0010039)
0.0 0.1 GO:0070973 COPI-coated vesicle budding(GO:0035964) protein localization to endoplasmic reticulum exit site(GO:0070973)
0.0 0.8 GO:0097006 regulation of plasma lipoprotein particle levels(GO:0097006)
0.0 0.2 GO:0032780 negative regulation of ATPase activity(GO:0032780)
0.0 0.3 GO:1903861 positive regulation of dendrite extension(GO:1903861)
0.0 0.5 GO:0000413 protein peptidyl-prolyl isomerization(GO:0000413)
0.0 0.0 GO:0035898 parathyroid hormone secretion(GO:0035898)
0.0 2.4 GO:0007605 sensory perception of sound(GO:0007605)
0.0 0.5 GO:0030488 tRNA methylation(GO:0030488)
0.0 1.0 GO:0043113 receptor clustering(GO:0043113)
0.0 0.4 GO:0010758 regulation of macrophage chemotaxis(GO:0010758)
0.0 0.3 GO:2000052 positive regulation of non-canonical Wnt signaling pathway(GO:2000052)
0.0 0.0 GO:0014826 vein smooth muscle contraction(GO:0014826)
0.0 0.1 GO:0009249 protein lipoylation(GO:0009249)
0.0 1.4 GO:0030518 intracellular steroid hormone receptor signaling pathway(GO:0030518)
0.0 0.1 GO:0015808 L-alanine transport(GO:0015808)
0.0 0.2 GO:0015858 nucleoside transport(GO:0015858)
0.0 0.2 GO:0031115 negative regulation of microtubule polymerization(GO:0031115)
0.0 0.2 GO:0000289 nuclear-transcribed mRNA poly(A) tail shortening(GO:0000289)
0.0 0.5 GO:0030855 epithelial cell differentiation(GO:0030855)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 4.0 GO:0036056 filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057)
0.4 2.0 GO:0048237 rough endoplasmic reticulum lumen(GO:0048237)
0.4 1.6 GO:1990421 subtelomeric heterochromatin(GO:1990421) nuclear subtelomeric heterochromatin(GO:1990707)
0.3 2.8 GO:0045298 tubulin complex(GO:0045298)
0.2 1.5 GO:0070695 FHF complex(GO:0070695)
0.1 0.7 GO:0070826 paraferritin complex(GO:0070826)
0.1 1.8 GO:0030057 desmosome(GO:0030057)
0.1 1.2 GO:0097427 microtubule bundle(GO:0097427)
0.1 1.6 GO:0031528 microvillus membrane(GO:0031528)
0.1 11.5 GO:0005913 cell-cell adherens junction(GO:0005913)
0.1 0.5 GO:0043527 tRNA methyltransferase complex(GO:0043527)
0.1 1.7 GO:0016460 myosin II complex(GO:0016460)
0.1 0.6 GO:0031314 extrinsic component of mitochondrial inner membrane(GO:0031314)
0.1 2.8 GO:0005779 integral component of peroxisomal membrane(GO:0005779)
0.1 0.4 GO:1990130 Iml1 complex(GO:1990130)
0.1 0.9 GO:0042622 photoreceptor outer segment membrane(GO:0042622)
0.1 7.1 GO:0016605 PML body(GO:0016605)
0.1 0.4 GO:0005853 eukaryotic translation elongation factor 1 complex(GO:0005853)
0.1 0.8 GO:0036038 MKS complex(GO:0036038)
0.1 0.7 GO:0035686 sperm fibrous sheath(GO:0035686)
0.0 0.8 GO:0097225 sperm midpiece(GO:0097225)
0.0 0.2 GO:0042406 extrinsic component of endoplasmic reticulum membrane(GO:0042406)
0.0 0.8 GO:0005665 DNA-directed RNA polymerase II, core complex(GO:0005665)
0.0 0.8 GO:0005782 peroxisomal matrix(GO:0005782) microbody lumen(GO:0031907)
0.0 0.5 GO:0031932 TORC2 complex(GO:0031932)
0.0 0.2 GO:0031523 Myb complex(GO:0031523)
0.0 0.2 GO:0016593 Cdc73/Paf1 complex(GO:0016593)
0.0 3.0 GO:0030176 integral component of endoplasmic reticulum membrane(GO:0030176)
0.0 0.1 GO:0097433 dense body(GO:0097433)
0.0 0.9 GO:0030131 clathrin adaptor complex(GO:0030131)
0.0 1.0 GO:0048786 presynaptic active zone(GO:0048786)
0.0 4.1 GO:0043197 dendritic spine(GO:0043197)
0.0 0.2 GO:0020003 symbiont-containing vacuole(GO:0020003)
0.0 1.0 GO:0005882 intermediate filament(GO:0005882)
0.0 0.5 GO:0031526 brush border membrane(GO:0031526)
0.0 0.7 GO:0001772 immunological synapse(GO:0001772)
0.0 3.3 GO:0016323 basolateral plasma membrane(GO:0016323)
0.0 1.7 GO:0031225 anchored component of membrane(GO:0031225)
0.0 3.6 GO:0005578 proteinaceous extracellular matrix(GO:0005578)
0.0 1.4 GO:0016324 apical plasma membrane(GO:0016324)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
2.1 6.2 GO:0016167 glial cell-derived neurotrophic factor receptor activity(GO:0016167)
0.6 1.9 GO:0000822 inositol hexakisphosphate binding(GO:0000822)
0.6 2.3 GO:0034041 sterol-transporting ATPase activity(GO:0034041)
0.5 2.8 GO:0070699 type II activin receptor binding(GO:0070699)
0.4 2.8 GO:0099609 microtubule lateral binding(GO:0099609)
0.4 1.8 GO:0003835 beta-galactoside alpha-2,6-sialyltransferase activity(GO:0003835)
0.3 1.0 GO:0001875 lipopolysaccharide receptor activity(GO:0001875)
0.3 11.3 GO:0042805 actinin binding(GO:0042805)
0.3 0.8 GO:0004994 somatostatin receptor activity(GO:0004994)
0.2 0.9 GO:0032896 palmitoyl-CoA 9-desaturase activity(GO:0032896)
0.2 1.6 GO:0015616 DNA translocase activity(GO:0015616)
0.2 0.6 GO:0005124 scavenger receptor binding(GO:0005124)
0.2 0.8 GO:0070573 tripeptidyl-peptidase activity(GO:0008240) metallodipeptidase activity(GO:0070573)
0.2 1.2 GO:0004468 lysine N-acetyltransferase activity, acting on acetyl phosphate as donor(GO:0004468)
0.2 0.7 GO:0004459 L-lactate dehydrogenase activity(GO:0004459)
0.2 1.1 GO:0047184 1-acylglycerophosphocholine O-acyltransferase activity(GO:0047184)
0.2 1.0 GO:0016936 galactoside binding(GO:0016936)
0.1 0.7 GO:0005324 long-chain fatty acid transporter activity(GO:0005324)
0.1 0.7 GO:0015086 cadmium ion transmembrane transporter activity(GO:0015086) lead ion transmembrane transporter activity(GO:0015094) vanadium ion transmembrane transporter activity(GO:0015100) ferrous iron uptake transmembrane transporter activity(GO:0015639)
0.1 2.9 GO:0016709 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen(GO:0016709)
0.1 0.9 GO:0052650 NADP-retinol dehydrogenase activity(GO:0052650)
0.1 2.9 GO:0005248 voltage-gated sodium channel activity(GO:0005248)
0.1 1.4 GO:0036042 long-chain fatty acyl-CoA binding(GO:0036042)
0.1 0.8 GO:0003876 AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
0.1 2.8 GO:0005337 nucleoside transmembrane transporter activity(GO:0005337)
0.1 2.0 GO:0030247 pattern binding(GO:0001871) polysaccharide binding(GO:0030247)
0.1 0.5 GO:0000293 ferric-chelate reductase activity(GO:0000293)
0.1 2.1 GO:0070016 armadillo repeat domain binding(GO:0070016)
0.1 0.4 GO:0004832 valine-tRNA ligase activity(GO:0004832)
0.1 1.2 GO:0097109 neuroligin family protein binding(GO:0097109)
0.1 2.8 GO:0030676 Rac guanyl-nucleotide exchange factor activity(GO:0030676)
0.1 1.0 GO:0048018 receptor agonist activity(GO:0048018)
0.1 0.3 GO:0004126 cytidine deaminase activity(GO:0004126)
0.1 0.5 GO:0051525 NFAT protein binding(GO:0051525)
0.1 0.2 GO:0052658 inositol-1,4,5-trisphosphate 5-phosphatase activity(GO:0052658)
0.1 2.4 GO:0051059 NF-kappaB binding(GO:0051059)
0.1 0.2 GO:0004074 biliverdin reductase activity(GO:0004074)
0.1 7.2 GO:0001191 transcriptional repressor activity, RNA polymerase II transcription factor binding(GO:0001191)
0.1 1.5 GO:0051959 dynein light intermediate chain binding(GO:0051959)
0.1 0.2 GO:0010857 calcium-dependent protein kinase activity(GO:0010857)
0.1 1.8 GO:0005154 epidermal growth factor receptor binding(GO:0005154)
0.0 0.2 GO:0015142 citrate transmembrane transporter activity(GO:0015137) tricarboxylic acid transmembrane transporter activity(GO:0015142)
0.0 0.2 GO:0050700 CARD domain binding(GO:0050700)
0.0 0.3 GO:0004887 thyroid hormone receptor activity(GO:0004887)
0.0 1.8 GO:0004683 calmodulin-dependent protein kinase activity(GO:0004683)
0.0 0.2 GO:0004030 aldehyde dehydrogenase [NAD(P)+] activity(GO:0004030)
0.0 0.1 GO:0046997 sarcosine dehydrogenase activity(GO:0008480) oxidoreductase activity, acting on the CH-NH group of donors, flavin as acceptor(GO:0046997)
0.0 0.2 GO:0008449 N-acetylglucosamine-6-sulfatase activity(GO:0008449)
0.0 0.5 GO:0019104 DNA N-glycosylase activity(GO:0019104)
0.0 0.4 GO:0004000 adenosine deaminase activity(GO:0004000)
0.0 0.2 GO:0005005 transmembrane-ephrin receptor activity(GO:0005005) PH domain binding(GO:0042731)
0.0 0.1 GO:0016979 lipoate-protein ligase activity(GO:0016979)
0.0 0.4 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.0 0.2 GO:0016802 adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802)
0.0 0.7 GO:0004709 MAP kinase kinase kinase activity(GO:0004709)
0.0 0.1 GO:0015173 hydrogen:amino acid symporter activity(GO:0005280) aromatic amino acid transmembrane transporter activity(GO:0015173)
0.0 0.5 GO:0005528 macrolide binding(GO:0005527) FK506 binding(GO:0005528)
0.0 1.0 GO:0005089 Rho guanyl-nucleotide exchange factor activity(GO:0005089)
0.0 0.6 GO:0003746 translation elongation factor activity(GO:0003746)
0.0 2.1 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.0 0.7 GO:0000993 RNA polymerase II core binding(GO:0000993)
0.0 0.2 GO:0004143 diacylglycerol kinase activity(GO:0004143)
0.0 0.2 GO:0032051 clathrin light chain binding(GO:0032051)
0.0 0.8 GO:0003899 DNA-directed RNA polymerase activity(GO:0003899)
0.0 1.2 GO:0005518 collagen binding(GO:0005518)
0.0 1.2 GO:0017022 myosin binding(GO:0017022)
0.0 0.3 GO:0050321 tau-protein kinase activity(GO:0050321)
0.0 0.3 GO:0003841 1-acylglycerol-3-phosphate O-acyltransferase activity(GO:0003841)
0.0 0.4 GO:0017112 Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.0 0.2 GO:0098641 cadherin binding involved in cell-cell adhesion(GO:0098641)
0.0 0.8 GO:0001540 beta-amyloid binding(GO:0001540)
0.0 0.8 GO:0004714 transmembrane receptor protein tyrosine kinase activity(GO:0004714)
0.0 0.5 GO:0008175 tRNA methyltransferase activity(GO:0008175)
0.0 2.0 GO:0017137 Rab GTPase binding(GO:0017137)
0.0 0.0 GO:0004743 pyruvate kinase activity(GO:0004743)
0.0 0.2 GO:0005545 1-phosphatidylinositol binding(GO:0005545)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 2.8 PID_P38_GAMMA_DELTA_PATHWAY Signaling mediated by p38-gamma and p38-delta
0.1 4.1 PID_IL12_STAT4_PATHWAY IL12 signaling mediated by STAT4
0.1 1.8 PID_ERBB_NETWORK_PATHWAY ErbB receptor signaling network
0.1 2.0 PID_INTEGRIN5_PATHWAY Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.1 2.7 PID_ARF6_DOWNSTREAM_PATHWAY Arf6 downstream pathway
0.1 0.8 SA_MMP_CYTOKINE_CONNECTION Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.0 3.0 PID_ERA_GENOMIC_PATHWAY Validated nuclear estrogen receptor alpha network
0.0 1.0 PID_WNT_SIGNALING_PATHWAY Wnt signaling network
0.0 0.7 PID_P38_MKK3_6PATHWAY p38 MAPK signaling pathway
0.0 1.2 PID_CDC42_REG_PATHWAY Regulation of CDC42 activity
0.0 1.2 PID_P38_ALPHA_BETA_DOWNSTREAM_PATHWAY Signaling mediated by p38-alpha and p38-beta
0.0 0.7 PID_HIF2PATHWAY HIF-2-alpha transcription factor network
0.0 1.3 PID_REG_GR_PATHWAY Glucocorticoid receptor regulatory network
0.0 2.2 NABA_ECM_REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.0 0.2 PID_EPHA_FWDPATHWAY EPHA forward signaling
0.0 0.3 PID_BETA_CATENIN_DEG_PATHWAY Degradation of beta catenin
0.0 1.6 NABA_ECM_AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.0 0.7 PID_HIF1_TFPATHWAY HIF-1-alpha transcription factor network
0.0 0.6 PID_SHP2_PATHWAY SHP2 signaling

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 4.6 REACTOME_ABCA_TRANSPORTERS_IN_LIPID_HOMEOSTASIS Genes involved in ABCA transporters in lipid homeostasis
0.1 2.8 REACTOME_CASPASE_MEDIATED_CLEAVAGE_OF_CYTOSKELETAL_PROTEINS Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.1 1.1 REACTOME_ACYL_CHAIN_REMODELLING_OF_PS Genes involved in Acyl chain remodelling of PS
0.1 5.6 REACTOME_NCAM1_INTERACTIONS Genes involved in NCAM1 interactions
0.1 2.8 REACTOME_NEPHRIN_INTERACTIONS Genes involved in Nephrin interactions
0.1 2.6 REACTOME_SYNTHESIS_OF_VERY_LONG_CHAIN_FATTY_ACYL_COAS Genes involved in Synthesis of very long-chain fatty acyl-CoAs
0.1 1.0 REACTOME_HDL_MEDIATED_LIPID_TRANSPORT Genes involved in HDL-mediated lipid transport
0.1 0.8 REACTOME_SYNTHESIS_OF_PE Genes involved in Synthesis of PE
0.1 2.8 REACTOME_TRANSPORT_OF_VITAMINS_NUCLEOSIDES_AND_RELATED_MOLECULES Genes involved in Transport of vitamins, nucleosides, and related molecules
0.1 1.0 REACTOME_GABA_A_RECEPTOR_ACTIVATION Genes involved in GABA A receptor activation
0.1 0.9 REACTOME_NEF_MEDIATED_DOWNREGULATION_OF_MHC_CLASS_I_COMPLEX_CELL_SURFACE_EXPRESSION Genes involved in Nef mediated downregulation of MHC class I complex cell surface expression
0.0 0.6 REACTOME_CALNEXIN_CALRETICULIN_CYCLE Genes involved in Calnexin/calreticulin cycle
0.0 0.8 REACTOME_VIRAL_MESSENGER_RNA_SYNTHESIS Genes involved in Viral Messenger RNA Synthesis
0.0 0.7 REACTOME_ERKS_ARE_INACTIVATED Genes involved in ERKs are inactivated
0.0 0.8 REACTOME_PURINE_SALVAGE Genes involved in Purine salvage
0.0 0.6 REACTOME_TIE2_SIGNALING Genes involved in Tie2 Signaling
0.0 0.7 REACTOME_METABOLISM_OF_STEROID_HORMONES_AND_VITAMINS_A_AND_D Genes involved in Metabolism of steroid hormones and vitamins A and D
0.0 0.2 REACTOME_FATTY_ACYL_COA_BIOSYNTHESIS Genes involved in Fatty Acyl-CoA Biosynthesis
0.0 0.7 REACTOME_PYRUVATE_METABOLISM Genes involved in Pyruvate metabolism
0.0 0.6 REACTOME_TETRAHYDROBIOPTERIN_BH4_SYNTHESIS_RECYCLING_SALVAGE_AND_REGULATION Genes involved in Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation
0.0 0.8 REACTOME_PRE_NOTCH_TRANSCRIPTION_AND_TRANSLATION Genes involved in Pre-NOTCH Transcription and Translation
0.0 3.0 REACTOME_G_ALPHA_Q_SIGNALLING_EVENTS Genes involved in G alpha (q) signalling events
0.0 1.2 REACTOME_INTEGRIN_CELL_SURFACE_INTERACTIONS Genes involved in Integrin cell surface interactions
0.0 1.0 REACTOME_CLASS_B_2_SECRETIN_FAMILY_RECEPTORS Genes involved in Class B/2 (Secretin family receptors)
0.0 0.2 REACTOME_ACTIVATION_OF_RAC Genes involved in Activation of Rac
0.0 0.4 REACTOME_MITOCHONDRIAL_TRNA_AMINOACYLATION Genes involved in Mitochondrial tRNA aminoacylation
0.0 0.8 REACTOME_PEPTIDE_LIGAND_BINDING_RECEPTORS Genes involved in Peptide ligand-binding receptors
0.0 0.3 REACTOME_TRIGLYCERIDE_BIOSYNTHESIS Genes involved in Triglyceride Biosynthesis
0.0 0.2 REACTOME_METABOLISM_OF_PORPHYRINS Genes involved in Metabolism of porphyrins