Motif ID: Homez

Z-value: 0.663


Transcription factors associated with Homez:

Gene SymbolEntrez IDGene Name
Homez ENSMUSG00000057156.9 Homez

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Homezmm10_v2_chr14_-_54870913_54870961-0.231.8e-01Click!


Activity profile for motif Homez.

activity profile for motif Homez


Sorted Z-values histogram for motif Homez

Sorted Z-values for motif Homez



Network of associatons between targets according to the STRING database.



First level regulatory network of Homez

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr4_-_117178726 4.617 ENSMUST00000153953.1
ENSMUST00000106436.1
 Kif2c

kinesin family member 2C

chr6_-_23248264 4.535 ENSMUST00000031709.5
 Fezf1
Fez family zinc finger 1
chr4_+_44300876 3.687 ENSMUST00000045607.5
 Melk
maternal embryonic leucine zipper kinase
chr8_-_4779513 3.398 ENSMUST00000022945.7
 Shcbp1
Shc SH2-domain binding protein 1
chr3_+_5218546 3.293 ENSMUST00000026284.6
 Zfhx4
zinc finger homeodomain 4
chr11_+_101627942 2.814 ENSMUST00000010506.3
 Rdm1
RAD52 motif 1
chr3_+_5218516 2.686 ENSMUST00000175866.1
 Zfhx4
zinc finger homeodomain 4
chr16_-_26989974 2.528 ENSMUST00000089832.4
 Gmnc
geminin coiled-coil domain containing
chr9_+_91368811 2.387 ENSMUST00000173054.1
 Zic4
zinc finger protein of the cerebellum 4
chr8_-_72305276 2.229 ENSMUST00000075602.6
 Gm10282
predicted pseudogene 10282
chr9_+_91368970 2.188 ENSMUST00000172646.1
 Zic4
zinc finger protein of the cerebellum 4
chr3_+_90220783 2.186 ENSMUST00000065418.6
 Rab13
RAB13, member RAS oncogene family
chr8_+_116921735 2.088 ENSMUST00000034205.4
 Cenpn
centromere protein N
chr18_-_62756275 1.969 ENSMUST00000067450.1
ENSMUST00000048109.5
 2700046A07Rik

RIKEN cDNA 2700046A07 gene

chr6_+_137754529 1.935 ENSMUST00000087675.6
 Dera
2-deoxyribose-5-phosphate aldolase homolog (C. elegans)
chr18_+_50030977 1.889 ENSMUST00000145726.1
ENSMUST00000128377.1
 Tnfaip8

tumor necrosis factor, alpha-induced protein 8

chr19_-_30175414 1.711 ENSMUST00000025778.7
 Gldc
glycine decarboxylase
chr3_-_63899437 1.704 ENSMUST00000159188.1
ENSMUST00000177143.1
 Plch1

phospholipase C, eta 1

chr14_-_27508460 1.650 ENSMUST00000050480.6
 Ccdc66
coiled-coil domain containing 66
chr1_-_138619687 1.645 ENSMUST00000027642.2
 Nek7
NIMA (never in mitosis gene a)-related expressed kinase 7

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 96 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.9 4.6 GO:0030951 establishment or maintenance of microtubule cytoskeleton polarity(GO:0030951)
0.8 4.5 GO:0021797 forebrain anterior/posterior pattern specification(GO:0021797)
0.1 3.8 GO:0008631 intrinsic apoptotic signaling pathway in response to oxidative stress(GO:0008631)
0.1 3.2 GO:0006270 DNA replication initiation(GO:0006270)
0.0 2.6 GO:0008543 fibroblast growth factor receptor signaling pathway(GO:0008543)
0.5 2.5 GO:0007089 traversing start control point of mitotic cell cycle(GO:0007089)
0.4 2.5 GO:0032196 regulation of transposition(GO:0010528) negative regulation of transposition(GO:0010529) transposition(GO:0032196)
0.4 2.3 GO:0046502 uroporphyrinogen III metabolic process(GO:0046502)
0.4 2.2 GO:0097368 establishment of Sertoli cell barrier(GO:0097368)
0.1 2.2 GO:0032611 interleukin-1 beta production(GO:0032611)
0.1 2.1 GO:0034508 centromere complex assembly(GO:0034508)
0.5 1.9 GO:0046121 deoxyribonucleoside catabolic process(GO:0046121)
0.6 1.7 GO:0006546 glycine catabolic process(GO:0006546) glycine decarboxylation via glycine cleavage system(GO:0019464)
0.6 1.7 GO:0060060 post-embryonic retina morphogenesis in camera-type eye(GO:0060060)
0.3 1.6 GO:0072513 positive regulation of secondary heart field cardioblast proliferation(GO:0072513)
0.1 1.6 GO:1904355 positive regulation of telomere capping(GO:1904355)
0.0 1.6 GO:0045599 negative regulation of fat cell differentiation(GO:0045599)
0.0 1.5 GO:0007608 sensory perception of smell(GO:0007608)
0.5 1.4 GO:0050713 negative regulation of interleukin-1 beta secretion(GO:0050713)
0.2 1.4 GO:0006975 DNA damage induced protein phosphorylation(GO:0006975)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 43 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 4.0 GO:0035371 microtubule plus-end(GO:0035371)
0.0 2.5 GO:0000776 kinetochore(GO:0000776)
0.1 2.2 GO:0032593 insulin-responsive compartment(GO:0032593)
0.0 1.6 GO:1990204 oxidoreductase complex(GO:1990204)
0.4 1.5 GO:0071006 U2-type catalytic step 1 spliceosome(GO:0071006)
0.2 1.4 GO:0042406 extrinsic component of endoplasmic reticulum membrane(GO:0042406)
0.0 1.4 GO:0005657 replication fork(GO:0005657)
0.0 1.4 GO:0070469 respiratory chain(GO:0070469)
0.4 1.2 GO:1990423 RZZ complex(GO:1990423)
0.3 1.1 GO:0061702 inflammasome complex(GO:0061702)
0.1 1.1 GO:0000276 mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276)
0.1 1.1 GO:0042555 MCM complex(GO:0042555)
0.1 0.9 GO:0061574 ASAP complex(GO:0061574)
0.1 0.9 GO:0000347 THO complex(GO:0000347) THO complex part of transcription export complex(GO:0000445)
0.1 0.9 GO:0044754 autolysosome(GO:0044754)
0.0 0.9 GO:0055038 recycling endosome membrane(GO:0055038)
0.0 0.9 GO:0000775 chromosome, centromeric region(GO:0000775)
0.1 0.8 GO:0070652 HAUS complex(GO:0070652)
0.1 0.8 GO:0031415 NatA complex(GO:0031415)
0.0 0.8 GO:0031430 M band(GO:0031430)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 72 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 10.5 GO:0043565 sequence-specific DNA binding(GO:0043565)
0.0 4.9 GO:0001078 transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078)
0.3 4.6 GO:0051010 microtubule plus-end binding(GO:0051010)
0.1 3.7 GO:0004715 non-membrane spanning protein tyrosine kinase activity(GO:0004715)
0.1 3.0 GO:0042169 SH2 domain binding(GO:0042169)
0.6 2.5 GO:0047844 deoxycytidine deaminase activity(GO:0047844)
0.1 2.3 GO:0008198 ferrous iron binding(GO:0008198)
0.1 2.2 GO:0034236 protein kinase A catalytic subunit binding(GO:0034236)
0.1 1.9 GO:0016832 aldehyde-lyase activity(GO:0016832)
0.0 1.9 GO:0043027 cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027)
0.1 1.7 GO:0016638 oxidoreductase activity, acting on the CH-NH2 group of donors(GO:0016638)
0.1 1.7 GO:0004435 phosphatidylinositol phospholipase C activity(GO:0004435)
0.5 1.6 GO:0036132 13-prostaglandin reductase activity(GO:0036132) 15-oxoprostaglandin 13-oxidase activity(GO:0047522)
0.3 1.6 GO:0004165 dodecenoyl-CoA delta-isomerase activity(GO:0004165)
0.0 1.5 GO:0001227 transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001227)
0.5 1.4 GO:0035402 histone kinase activity (H3-T11 specific)(GO:0035402)
0.2 1.4 GO:0048101 calmodulin-dependent cyclic-nucleotide phosphodiesterase activity(GO:0004117) calcium- and calmodulin-regulated 3',5'-cyclic-GMP phosphodiesterase activity(GO:0048101)
0.1 1.4 GO:0050897 cobalt ion binding(GO:0050897)
0.0 1.4 GO:0050136 NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.0 1.4 GO:0070063 RNA polymerase binding(GO:0070063)

Gene overrepresentation in C2:CP category:

Showing 1 to 9 of 9 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 4.6 PID_AURORA_B_PATHWAY Aurora B signaling
0.0 2.2 NABA_SECRETED_FACTORS Genes encoding secreted soluble factors
0.2 1.4 SA_G2_AND_M_PHASES Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
0.0 1.4 PID_MYC_PATHWAY C-MYC pathway
0.0 1.2 PID_E2F_PATHWAY E2F transcription factor network
0.0 0.7 PID_SMAD2_3PATHWAY Regulation of cytoplasmic and nuclear SMAD2/3 signaling
0.0 0.4 PID_IL6_7_PATHWAY IL6-mediated signaling events
0.0 0.3 PID_TOLL_ENDOGENOUS_PATHWAY Endogenous TLR signaling
0.0 0.2 PID_S1P_S1P4_PATHWAY S1P4 pathway

Gene overrepresentation in C2:CP:REACTOME category:

Showing 1 to 20 of 23 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.2 4.6 REACTOME_KINESINS Genes involved in Kinesins
0.1 3.7 REACTOME_ACTIVATION_OF_THE_PRE_REPLICATIVE_COMPLEX Genes involved in Activation of the pre-replicative complex
0.1 2.8 REACTOME_DEPOSITION_OF_NEW_CENPA_CONTAINING_NUCLEOSOMES_AT_THE_CENTROMERE Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere
0.1 2.3 REACTOME_METABOLISM_OF_PORPHYRINS Genes involved in Metabolism of porphyrins
0.1 1.6 REACTOME_MITOCHONDRIAL_FATTY_ACID_BETA_OXIDATION Genes involved in Mitochondrial Fatty Acid Beta-Oxidation
0.1 1.4 REACTOME_G2_M_DNA_DAMAGE_CHECKPOINT Genes involved in G2/M DNA damage checkpoint
0.0 1.4 REACTOME_INTERFERON_GAMMA_SIGNALING Genes involved in Interferon gamma signaling
0.0 1.2 REACTOME_MITOTIC_PROMETAPHASE Genes involved in Mitotic Prometaphase
0.1 1.1 REACTOME_INFLAMMASOMES Genes involved in Inflammasomes
0.0 1.0 REACTOME_LOSS_OF_NLP_FROM_MITOTIC_CENTROSOMES Genes involved in Loss of Nlp from mitotic centrosomes
0.0 0.8 REACTOME_ANTIVIRAL_MECHANISM_BY_IFN_STIMULATED_GENES Genes involved in Antiviral mechanism by IFN-stimulated genes
0.0 0.7 REACTOME_CHYLOMICRON_MEDIATED_LIPID_TRANSPORT Genes involved in Chylomicron-mediated lipid transport
0.1 0.6 REACTOME_CREATION_OF_C4_AND_C2_ACTIVATORS Genes involved in Creation of C4 and C2 activators
0.0 0.6 REACTOME_FORMATION_OF_INCISION_COMPLEX_IN_GG_NER Genes involved in Formation of incision complex in GG-NER
0.0 0.5 REACTOME_INTERACTIONS_OF_VPR_WITH_HOST_CELLULAR_PROTEINS Genes involved in Interactions of Vpr with host cellular proteins
0.0 0.5 REACTOME_ASSOCIATION_OF_TRIC_CCT_WITH_TARGET_PROTEINS_DURING_BIOSYNTHESIS Genes involved in Association of TriC/CCT with target proteins during biosynthesis
0.0 0.5 REACTOME_APOPTOTIC_CLEAVAGE_OF_CELLULAR_PROTEINS Genes involved in Apoptotic cleavage of cellular proteins
0.0 0.4 REACTOME_PURINE_CATABOLISM Genes involved in Purine catabolism
0.0 0.4 REACTOME_SIGNALING_BY_FGFR1_FUSION_MUTANTS Genes involved in Signaling by FGFR1 fusion mutants
0.0 0.3 REACTOME_THE_ACTIVATION_OF_ARYLSULFATASES Genes involved in The activation of arylsulfatases