Motif ID: Hoxa1

Z-value: 1.102


Transcription factors associated with Hoxa1:

Gene SymbolEntrez IDGene Name
Hoxa1 ENSMUSG00000029844.9 Hoxa1



Activity profile for motif Hoxa1.

activity profile for motif Hoxa1


Sorted Z-values histogram for motif Hoxa1

Sorted Z-values for motif Hoxa1



Network of associatons between targets according to the STRING database.



First level regulatory network of Hoxa1

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr9_+_15239045 9.331 ENSMUST00000034413.6
Vstm5
V-set and transmembrane domain containing 5
chr15_-_95528702 6.670 ENSMUST00000166170.1
Nell2
NEL-like 2
chr7_+_73391160 6.466 ENSMUST00000128471.1
Rgma
RGM domain family, member A
chr14_+_70077375 3.883 ENSMUST00000035908.1
Egr3
early growth response 3
chr2_+_158375638 3.777 ENSMUST00000109488.1
Snhg11
small nucleolar RNA host gene 11
chr3_+_55782500 3.645 ENSMUST00000075422.4
Mab21l1
mab-21-like 1 (C. elegans)
chr10_+_81628702 3.366 ENSMUST00000129622.1
Ankrd24
ankyrin repeat domain 24
chr4_-_143299498 3.336 ENSMUST00000030317.7
Pdpn
podoplanin
chr2_+_90885860 2.785 ENSMUST00000111466.2
C1qtnf4
C1q and tumor necrosis factor related protein 4
chr4_-_35845204 2.775 ENSMUST00000164772.1
ENSMUST00000065173.2
Lingo2

leucine rich repeat and Ig domain containing 2

chr2_+_152962485 2.750 ENSMUST00000099197.2
ENSMUST00000103155.3
Ttll9

tubulin tyrosine ligase-like family, member 9

chr2_+_65845767 2.729 ENSMUST00000122912.1
Csrnp3
cysteine-serine-rich nuclear protein 3
chr19_-_41743665 2.603 ENSMUST00000025993.3
Slit1
slit homolog 1 (Drosophila)
chr5_+_27261916 2.566 ENSMUST00000101471.3
Dpp6
dipeptidylpeptidase 6
chr2_-_26246707 2.562 ENSMUST00000166349.1
C030048H21Rik
RIKEN cDNA C030048H21 gene
chr2_+_65845833 2.561 ENSMUST00000053910.3
Csrnp3
cysteine-serine-rich nuclear protein 3
chr2_+_163225363 2.461 ENSMUST00000099110.3
ENSMUST00000165937.1
Tox2

TOX high mobility group box family member 2

chr15_+_98167806 2.336 ENSMUST00000031914.4
AI836003
expressed sequence AI836003
chr15_+_74516196 2.247 ENSMUST00000042035.9
Bai1
brain-specific angiogenesis inhibitor 1
chr3_-_110143937 2.222 ENSMUST00000051253.3
Ntng1
netrin G1
chr10_+_26078255 2.159 ENSMUST00000041011.3
Gm9767
predicted gene 9767
chr6_-_136875794 2.055 ENSMUST00000032342.1
Mgp
matrix Gla protein
chr14_+_66344369 2.012 ENSMUST00000118426.1
ENSMUST00000121955.1
ENSMUST00000120229.1
ENSMUST00000134440.1
Stmn4



stathmin-like 4



chr3_+_68572245 1.917 ENSMUST00000170788.2
Schip1
schwannomin interacting protein 1
chr17_-_25081138 1.908 ENSMUST00000024984.6
Tmem204
transmembrane protein 204
chr4_-_106799779 1.889 ENSMUST00000145061.1
ENSMUST00000102762.3
Acot11

acyl-CoA thioesterase 11

chr14_+_66344296 1.825 ENSMUST00000152093.1
ENSMUST00000074523.6
Stmn4

stathmin-like 4

chr7_-_30534180 1.797 ENSMUST00000044338.4
Arhgap33
Rho GTPase activating protein 33
chr2_+_165595009 1.713 ENSMUST00000088132.6
Eya2
eyes absent 2 homolog (Drosophila)
chr10_+_81628570 1.702 ENSMUST00000153573.1
ENSMUST00000119336.1
Ankrd24

ankyrin repeat domain 24

chr17_+_55445375 1.691 ENSMUST00000133899.1
ENSMUST00000086878.3
St6gal2

beta galactoside alpha 2,6 sialyltransferase 2

chr13_+_31806627 1.602 ENSMUST00000062292.2
Foxc1
forkhead box C1
chr10_+_14523062 1.568 ENSMUST00000096020.5
Gm10335
predicted gene 10335
chr10_+_79988584 1.541 ENSMUST00000004784.4
ENSMUST00000105374.1
Cnn2

calponin 2

chr13_-_60177357 1.528 ENSMUST00000065086.4
Gas1
growth arrest specific 1
chr5_+_137030275 1.515 ENSMUST00000041543.8
Vgf
VGF nerve growth factor inducible
chr6_-_52012476 1.504 ENSMUST00000078214.5
Skap2
src family associated phosphoprotein 2
chr4_-_143299463 1.465 ENSMUST00000119654.1
Pdpn
podoplanin
chr1_+_153665274 1.461 ENSMUST00000152114.1
ENSMUST00000111812.1
Rgs8

regulator of G-protein signaling 8

chr4_+_101507947 1.446 ENSMUST00000149047.1
ENSMUST00000106929.3
Dnajc6

DnaJ (Hsp40) homolog, subfamily C, member 6

chr4_+_101507855 1.430 ENSMUST00000038207.5
Dnajc6
DnaJ (Hsp40) homolog, subfamily C, member 6
chr8_-_11312731 1.417 ENSMUST00000033898.9
Col4a1
collagen, type IV, alpha 1
chr9_-_4796218 1.388 ENSMUST00000027020.6
ENSMUST00000063508.7
ENSMUST00000163309.1
Gria4


glutamate receptor, ionotropic, AMPA4 (alpha 4)


chr11_-_102296618 1.315 ENSMUST00000107132.2
ENSMUST00000073234.2
Atxn7l3

ataxin 7-like 3

chr7_-_16917184 1.265 ENSMUST00000173139.1
Calm3
calmodulin 3
chr17_+_70522083 1.252 ENSMUST00000148486.1
ENSMUST00000133717.1
Dlgap1

discs, large (Drosophila) homolog-associated protein 1

chr2_-_152951688 1.241 ENSMUST00000109811.3
Dusp15
dual specificity phosphatase-like 15
chr9_+_59589288 1.155 ENSMUST00000121266.1
ENSMUST00000118164.1
Celf6

CUGBP, Elav-like family member 6

chr11_+_103774150 1.135 ENSMUST00000000127.5
Wnt3
wingless-related MMTV integration site 3
chr17_+_70522149 1.132 ENSMUST00000140728.1
Dlgap1
discs, large (Drosophila) homolog-associated protein 1
chr15_+_82252397 1.102 ENSMUST00000136948.1
1500009C09Rik
RIKEN cDNA 1500009C09 gene
chr10_-_63421739 1.039 ENSMUST00000054760.4
Gm7075
predicted gene 7075
chrX_+_38600626 1.036 ENSMUST00000000365.2
Mcts1
malignant T cell amplified sequence 1
chr1_+_89454769 1.030 ENSMUST00000027521.8
ENSMUST00000074945.5
Agap1

ArfGAP with GTPase domain, ankyrin repeat and PH domain 1

chr13_-_12340723 1.027 ENSMUST00000168193.1
ENSMUST00000110616.1
ENSMUST00000064204.7
Actn2


actinin alpha 2


chr3_-_89093358 1.026 ENSMUST00000090929.5
ENSMUST00000052539.6
Rusc1

RUN and SH3 domain containing 1

chr11_+_24080664 1.001 ENSMUST00000118955.1
Bcl11a
B cell CLL/lymphoma 11A (zinc finger protein)
chr8_-_117673682 0.996 ENSMUST00000173522.1
ENSMUST00000174450.1
Sdr42e1

short chain dehydrogenase/reductase family 42E, member 1

chr5_+_88583527 0.960 ENSMUST00000031229.6
Rufy3
RUN and FYVE domain containing 3
chr10_+_94576254 0.910 ENSMUST00000117929.1
Tmcc3
transmembrane and coiled coil domains 3
chr5_-_137684665 0.865 ENSMUST00000100544.4
ENSMUST00000031736.9
ENSMUST00000151839.1
Agfg2


ArfGAP with FG repeats 2


chr8_-_8639363 0.821 ENSMUST00000152698.1
Efnb2
ephrin B2
chr18_+_56562443 0.802 ENSMUST00000130163.1
ENSMUST00000132628.1
Phax

phosphorylated adaptor for RNA export

chr18_+_4994600 0.736 ENSMUST00000140448.1
Svil
supervillin
chr8_+_95825353 0.719 ENSMUST00000074053.4
Gm10094
predicted gene 10094
chr11_-_40755201 0.714 ENSMUST00000020576.7
Ccng1
cyclin G1
chr14_-_103844173 0.695 ENSMUST00000022718.3
Ednrb
endothelin receptor type B
chr2_+_112261926 0.662 ENSMUST00000028553.3
Nop10
NOP10 ribonucleoprotein
chr10_+_81628540 0.604 ENSMUST00000123896.1
Ankrd24
ankyrin repeat domain 24
chr5_-_135573036 0.591 ENSMUST00000004936.6
Ccl24
chemokine (C-C motif) ligand 24
chr16_-_18876655 0.579 ENSMUST00000023391.8
Mrpl40
mitochondrial ribosomal protein L40
chr7_+_144838590 0.527 ENSMUST00000105898.1
Fgf3
fibroblast growth factor 3
chr8_-_67515606 0.523 ENSMUST00000032981.5
Gm9755
predicted pseudogene 9755
chr12_-_80260356 0.513 ENSMUST00000021554.8
Actn1
actinin, alpha 1
chr9_-_21312255 0.422 ENSMUST00000115433.3
ENSMUST00000003397.7
Ap1m2

adaptor protein complex AP-1, mu 2 subunit

chr16_-_18876522 0.419 ENSMUST00000119273.1
Mrpl40
mitochondrial ribosomal protein L40
chrX_-_150812932 0.390 ENSMUST00000131241.1
ENSMUST00000147152.1
ENSMUST00000143843.1
Maged2


melanoma antigen, family D, 2


chr17_-_90455872 0.377 ENSMUST00000174337.1
ENSMUST00000172466.1
Nrxn1

neurexin I

chr16_+_23107413 0.348 ENSMUST00000023599.6
ENSMUST00000168891.1
Eif4a2

eukaryotic translation initiation factor 4A2

chr1_+_10993452 0.346 ENSMUST00000027056.5
Prex2
phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 2
chr6_+_91684061 0.344 ENSMUST00000032185.7
Slc6a6
solute carrier family 6 (neurotransmitter transporter, taurine), member 6
chr14_-_69503316 0.329 ENSMUST00000179116.2
Gm21464
predicted gene, 21464
chr11_-_20332654 0.310 ENSMUST00000004634.6
Slc1a4
solute carrier family 1 (glutamate/neutral amino acid transporter), member 4
chr12_+_53248677 0.286 ENSMUST00000101432.2
Npas3
neuronal PAS domain protein 3
chr13_+_72628802 0.260 ENSMUST00000074372.4
Irx2
Iroquois related homeobox 2 (Drosophila)
chr2_+_36230426 0.248 ENSMUST00000062069.5
Ptgs1
prostaglandin-endoperoxide synthase 1
chrX_-_8132770 0.244 ENSMUST00000130832.1
ENSMUST00000033506.6
ENSMUST00000115623.1
ENSMUST00000153839.1
Wdr13



WD repeat domain 13



chr10_-_78352469 0.209 ENSMUST00000138035.1
Agpat3
1-acylglycerol-3-phosphate O-acyltransferase 3
chr2_-_131043088 0.193 ENSMUST00000110240.3
ENSMUST00000066958.4
ENSMUST00000110235.1
Gfra4


glial cell line derived neurotrophic factor family receptor alpha 4


chr3_-_79145875 0.184 ENSMUST00000118340.1
Rapgef2
Rap guanine nucleotide exchange factor (GEF) 2
chr6_-_88446491 0.180 ENSMUST00000165242.1
Eefsec
eukaryotic elongation factor, selenocysteine-tRNA-specific
chr4_+_119814495 0.162 ENSMUST00000106307.2
Hivep3
human immunodeficiency virus type I enhancer binding protein 3
chr9_+_110344185 0.158 ENSMUST00000142100.1
Scap
SREBF chaperone
chr5_+_135369942 0.126 ENSMUST00000000940.8
Nsun5
NOL1/NOP2/Sun domain family, member 5
chr5_+_42067960 0.105 ENSMUST00000087332.4
Gm16223
predicted gene 16223
chrX_-_150813637 0.101 ENSMUST00000112700.1
Maged2
melanoma antigen, family D, 2
chr15_-_53346118 0.077 ENSMUST00000077273.2
Ext1
exostoses (multiple) 1
chr17_-_28622419 0.075 ENSMUST00000114767.1
Srpk1
serine/arginine-rich protein specific kinase 1
chr2_-_131042682 0.056 ENSMUST00000028787.5
ENSMUST00000110239.1
ENSMUST00000110234.1
Gfra4


glial cell line derived neurotrophic factor family receptor alpha 4


chr7_+_3694512 0.011 ENSMUST00000108627.3
Tsen34
tRNA splicing endonuclease 34 homolog (S. cerevisiae)
chr10_-_81545175 0.009 ENSMUST00000043604.5
Gna11
guanine nucleotide binding protein, alpha 11
chr13_+_72628831 0.007 ENSMUST00000169028.1
Irx2
Iroquois related homeobox 2 (Drosophila)

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
1.0 4.8 GO:1901731 positive regulation of platelet aggregation(GO:1901731)
0.6 6.7 GO:0046543 development of secondary female sexual characteristics(GO:0046543)
0.5 6.5 GO:1900121 negative regulation of receptor binding(GO:1900121)
0.5 1.6 GO:1902256 apoptotic process involved in outflow tract morphogenesis(GO:0003275) regulation of apoptotic process involved in outflow tract morphogenesis(GO:1902256) response to chemokine(GO:1990868) cellular response to chemokine(GO:1990869)
0.5 2.9 GO:0072318 clathrin coat disassembly(GO:0072318)
0.4 1.1 GO:0044339 canonical Wnt signaling pathway involved in osteoblast differentiation(GO:0044339)
0.4 2.6 GO:0033563 dorsal/ventral axon guidance(GO:0033563)
0.4 3.9 GO:0046643 regulation of gamma-delta T cell differentiation(GO:0045586) regulation of gamma-delta T cell activation(GO:0046643)
0.3 0.8 GO:0051030 snRNA transport(GO:0051030)
0.3 1.0 GO:0002188 translation reinitiation(GO:0002188)
0.3 1.0 GO:2001137 positive regulation of endocytic recycling(GO:2001137)
0.3 1.0 GO:1904800 regulation of neuron remodeling(GO:1904799) negative regulation of neuron remodeling(GO:1904800)
0.2 0.7 GO:0014826 vein smooth muscle contraction(GO:0014826)
0.2 1.4 GO:0061304 retinal blood vessel morphogenesis(GO:0061304)
0.2 0.6 GO:2000418 positive regulation of eosinophil migration(GO:2000418)
0.2 2.4 GO:0070842 aggresome assembly(GO:0070842)
0.2 1.3 GO:0016576 histone dephosphorylation(GO:0016576)
0.2 1.5 GO:0042473 outer ear morphogenesis(GO:0042473)
0.1 1.5 GO:0043084 penile erection(GO:0043084)
0.1 0.7 GO:0000454 snoRNA guided rRNA pseudouridine synthesis(GO:0000454)
0.1 1.9 GO:0001553 luteinization(GO:0001553)
0.1 1.5 GO:0007213 G-protein coupled acetylcholine receptor signaling pathway(GO:0007213)
0.1 0.8 GO:1903847 regulation of aorta morphogenesis(GO:1903847) positive regulation of aorta morphogenesis(GO:1903849)
0.1 0.4 GO:0090126 protein complex assembly involved in synapse maturation(GO:0090126)
0.1 1.7 GO:0006054 N-acetylneuraminate metabolic process(GO:0006054)
0.1 0.2 GO:1900377 negative regulation of melanin biosynthetic process(GO:0048022) negative regulation of secondary metabolite biosynthetic process(GO:1900377)
0.1 0.5 GO:0030916 otic vesicle formation(GO:0030916)
0.1 0.2 GO:0010700 negative regulation of norepinephrine secretion(GO:0010700)
0.1 0.5 GO:0070294 renal sodium ion absorption(GO:0070294)
0.1 0.3 GO:0015825 L-serine transport(GO:0015825)
0.1 5.3 GO:0010923 negative regulation of phosphatase activity(GO:0010923)
0.1 1.9 GO:0001945 lymph vessel development(GO:0001945)
0.1 0.3 GO:0072272 proximal/distal pattern formation involved in metanephric nephron development(GO:0072272)
0.1 3.8 GO:0007019 microtubule depolymerization(GO:0007019)
0.1 1.2 GO:0071625 vocalization behavior(GO:0071625)
0.1 2.6 GO:1901381 positive regulation of potassium ion transmembrane transport(GO:1901381)
0.1 1.4 GO:0051968 positive regulation of synaptic transmission, glutamatergic(GO:0051968)
0.0 1.9 GO:0009409 response to cold(GO:0009409)
0.0 1.5 GO:0071260 cellular response to mechanical stimulus(GO:0071260)
0.0 1.0 GO:2000114 regulation of establishment of cell polarity(GO:2000114)
0.0 1.3 GO:0016578 histone deubiquitination(GO:0016578)
0.0 0.5 GO:0051639 actin filament network formation(GO:0051639)
0.0 0.7 GO:0007095 mitotic G2 DNA damage checkpoint(GO:0007095)
0.0 2.8 GO:0051965 positive regulation of synapse assembly(GO:0051965)
0.0 2.1 GO:0030500 regulation of bone mineralization(GO:0030500)
0.0 1.2 GO:0048713 regulation of oligodendrocyte differentiation(GO:0048713)
0.0 0.2 GO:0006451 selenocysteine incorporation(GO:0001514) translational readthrough(GO:0006451)
0.0 0.2 GO:0061469 regulation of type B pancreatic cell proliferation(GO:0061469)
0.0 0.3 GO:0042711 maternal behavior(GO:0042711)
0.0 0.1 GO:0015014 heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0015014) embryonic skeletal joint development(GO:0072498)
0.0 0.1 GO:0070475 rRNA base methylation(GO:0070475)
0.0 0.3 GO:0015804 neutral amino acid transport(GO:0015804)
0.0 1.3 GO:0000086 G2/M transition of mitotic cell cycle(GO:0000086)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 4.8 GO:0097197 tetraspanin-enriched microdomain(GO:0097197)
0.3 1.4 GO:0005587 collagen type IV trimer(GO:0005587) network-forming collagen trimer(GO:0098642) collagen network(GO:0098645) basement membrane collagen trimer(GO:0098651)
0.2 1.4 GO:0032983 kainate selective glutamate receptor complex(GO:0032983)
0.2 0.7 GO:0090661 box H/ACA telomerase RNP complex(GO:0090661)
0.1 0.5 GO:0032127 dense core granule membrane(GO:0032127)
0.1 3.7 GO:0046658 anchored component of plasma membrane(GO:0046658)
0.1 1.0 GO:0071437 invadopodium(GO:0071437)
0.1 1.3 GO:0000124 SAGA complex(GO:0000124)
0.1 6.7 GO:0031225 anchored component of membrane(GO:0031225)
0.0 6.7 GO:0043204 perikaryon(GO:0043204)
0.0 1.5 GO:0032809 neuronal cell body membrane(GO:0032809)
0.0 3.8 GO:0008076 voltage-gated potassium channel complex(GO:0008076)
0.0 0.4 GO:0036056 filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057)
0.0 1.0 GO:0005865 striated muscle thin filament(GO:0005865)
0.0 1.5 GO:0030667 secretory granule membrane(GO:0030667)
0.0 1.5 GO:0001725 stress fiber(GO:0001725) contractile actin filament bundle(GO:0097517)
0.0 1.0 GO:0000315 organellar large ribosomal subunit(GO:0000315) mitochondrial large ribosomal subunit(GO:0005762)
0.0 0.9 GO:0022627 cytosolic small ribosomal subunit(GO:0022627)
0.0 5.3 GO:0014069 postsynaptic density(GO:0014069)
0.0 0.7 GO:0043034 costamere(GO:0043034)
0.0 0.4 GO:0030131 clathrin adaptor complex(GO:0030131)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 6.5 GO:1990459 transferrin receptor binding(GO:1990459)
0.4 4.8 GO:0015250 water channel activity(GO:0015250)
0.3 1.7 GO:0003835 beta-galactoside alpha-2,6-sialyltransferase activity(GO:0003835)
0.3 2.6 GO:0048495 Roundabout binding(GO:0048495)
0.3 1.3 GO:0031800 type 3 metabotropic glutamate receptor binding(GO:0031800)
0.2 0.7 GO:0004962 endothelin receptor activity(GO:0004962)
0.2 1.4 GO:0004971 AMPA glutamate receptor activity(GO:0004971)
0.2 1.0 GO:0003854 3-beta-hydroxy-delta5-steroid dehydrogenase activity(GO:0003854)
0.1 1.0 GO:0031432 thyroid hormone receptor coactivator activity(GO:0030375) titin binding(GO:0031432)
0.1 1.6 GO:0008301 DNA binding, bending(GO:0008301)
0.1 1.7 GO:0048018 receptor agonist activity(GO:0048018)
0.1 0.7 GO:0034513 box H/ACA snoRNA binding(GO:0034513)
0.1 1.4 GO:0048407 platelet-derived growth factor binding(GO:0048407)
0.1 1.9 GO:0047617 acyl-CoA hydrolase activity(GO:0047617)
0.1 0.2 GO:0016167 glial cell-derived neurotrophic factor receptor activity(GO:0016167)
0.1 6.7 GO:0005080 protein kinase C binding(GO:0005080)
0.1 1.5 GO:0005184 neuropeptide hormone activity(GO:0005184)
0.1 0.8 GO:0015643 toxic substance binding(GO:0015643)
0.0 5.8 GO:0004725 protein tyrosine phosphatase activity(GO:0004725)
0.0 0.2 GO:0031697 beta-1 adrenergic receptor binding(GO:0031697)
0.0 2.6 GO:0015459 potassium channel regulator activity(GO:0015459)
0.0 1.5 GO:0005070 SH3/SH2 adaptor activity(GO:0005070)
0.0 0.3 GO:0015180 L-alanine transmembrane transporter activity(GO:0015180) L-proline transmembrane transporter activity(GO:0015193) alanine transmembrane transporter activity(GO:0022858)
0.0 1.8 GO:0030374 ligand-dependent nuclear receptor transcription coactivator activity(GO:0030374)
0.0 1.5 GO:0001965 G-protein alpha-subunit binding(GO:0001965)
0.0 0.4 GO:0097109 neuroligin family protein binding(GO:0097109)
0.0 2.8 GO:0005125 cytokine activity(GO:0005125)
0.0 3.6 GO:0016779 nucleotidyltransferase activity(GO:0016779)
0.0 0.3 GO:0005328 neurotransmitter:sodium symporter activity(GO:0005328)
0.0 2.1 GO:0048306 calcium-dependent protein binding(GO:0048306)
0.0 0.5 GO:0005104 fibroblast growth factor receptor binding(GO:0005104)
0.0 0.2 GO:0035368 selenocysteine insertion sequence binding(GO:0035368)
0.0 1.2 GO:0003743 translation initiation factor activity(GO:0003743)
0.0 2.5 GO:0001085 RNA polymerase II transcription factor binding(GO:0001085)
0.0 2.3 GO:0016874 ligase activity(GO:0016874)
0.0 0.3 GO:0030676 Rac guanyl-nucleotide exchange factor activity(GO:0030676)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 6.5 PID_BMP_PATHWAY BMP receptor signaling
0.1 3.6 NABA_BASEMENT_MEMBRANES Genes encoding structural components of basement membranes
0.1 2.1 PID_FRA_PATHWAY Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.1 3.9 PID_NFAT_TFPATHWAY Calcineurin-regulated NFAT-dependent transcription in lymphocytes
0.1 7.0 NABA_ECM_GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.0 1.1 PID_WNT_SIGNALING_PATHWAY Wnt signaling network
0.0 1.5 PID_FOXM1_PATHWAY FOXM1 transcription factor network
0.0 1.0 PID_MAPK_TRK_PATHWAY Trk receptor signaling mediated by the MAPK pathway
0.0 0.5 PID_SYNDECAN_4_PATHWAY Syndecan-4-mediated signaling events
0.0 0.8 PID_EPHRINB_REV_PATHWAY Ephrin B reverse signaling
0.0 0.7 PID_ENDOTHELIN_PATHWAY Endothelins
0.0 0.7 PID_P53_REGULATION_PATHWAY p53 pathway

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.4 REACTOME_UNBLOCKING_OF_NMDA_RECEPTOR_GLUTAMATE_BINDING_AND_ACTIVATION Genes involved in Unblocking of NMDA receptor, glutamate binding and activation
0.2 9.1 REACTOME_NETRIN1_SIGNALING Genes involved in Netrin-1 signaling
0.1 1.5 REACTOME_SIGNAL_REGULATORY_PROTEIN_SIRP_FAMILY_INTERACTIONS Genes involved in Signal regulatory protein (SIRP) family interactions
0.1 2.3 REACTOME_CREB_PHOSPHORYLATION_THROUGH_THE_ACTIVATION_OF_CAMKII Genes involved in CREB phosphorylation through the activation of CaMKII
0.1 3.3 REACTOME_LYSOSOME_VESICLE_BIOGENESIS Genes involved in Lysosome Vesicle Biogenesis
0.0 0.5 REACTOME_FGFR1_LIGAND_BINDING_AND_ACTIVATION Genes involved in FGFR1 ligand binding and activation
0.0 0.3 REACTOME_NA_CL_DEPENDENT_NEUROTRANSMITTER_TRANSPORTERS Genes involved in Na+/Cl- dependent neurotransmitter transporters
0.0 0.5 REACTOME_NEPHRIN_INTERACTIONS Genes involved in Nephrin interactions
0.0 0.7 REACTOME_PEPTIDE_LIGAND_BINDING_RECEPTORS Genes involved in Peptide ligand-binding receptors
0.0 1.4 REACTOME_INTEGRIN_CELL_SURFACE_INTERACTIONS Genes involved in Integrin cell surface interactions
0.0 0.8 REACTOME_METABOLISM_OF_NON_CODING_RNA Genes involved in Metabolism of non-coding RNA
0.0 1.1 REACTOME_CLASS_B_2_SECRETIN_FAMILY_RECEPTORS Genes involved in Class B/2 (Secretin family receptors)
0.0 1.5 REACTOME_G_ALPHA_I_SIGNALLING_EVENTS Genes involved in G alpha (i) signalling events
0.0 0.3 REACTOME_DEADENYLATION_OF_MRNA Genes involved in Deadenylation of mRNA