Motif ID: Hoxa11_Hoxc12

Z-value: 0.964

Transcription factors associated with Hoxa11_Hoxc12:

Gene SymbolEntrez IDGene Name
Hoxa11 ENSMUSG00000038210.9 Hoxa11
Hoxc12 ENSMUSG00000050328.2 Hoxc12






Network of associatons between targets according to the STRING database.



First level regulatory network of Hoxa11_Hoxc12

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr17_+_35076902 8.547 ENSMUST00000172494.1
ENSMUST00000172678.1
ENSMUST00000013910.4
Ly6g6e


lymphocyte antigen 6 complex, locus G6E


chr1_-_56978534 8.239 ENSMUST00000177282.1
Satb2
special AT-rich sequence binding protein 2
chr6_+_108213086 6.969 ENSMUST00000032192.6
Itpr1
inositol 1,4,5-trisphosphate receptor 1
chr13_+_16014457 6.024 ENSMUST00000164993.1
Inhba
inhibin beta-A
chr14_+_80000292 4.501 ENSMUST00000088735.3
Olfm4
olfactomedin 4
chr4_+_136143497 4.075 ENSMUST00000008016.2
Id3
inhibitor of DNA binding 3
chr1_+_43730593 3.984 ENSMUST00000027217.8
1500015O10Rik
RIKEN cDNA 1500015O10 gene
chr7_-_142661858 3.357 ENSMUST00000145896.2
Igf2
insulin-like growth factor 2
chr9_+_53771499 3.253 ENSMUST00000048670.8
Slc35f2
solute carrier family 35, member F2
chr5_+_66968961 3.079 ENSMUST00000132991.1
Limch1
LIM and calponin homology domains 1
chr17_+_6270475 2.857 ENSMUST00000088940.4
Tmem181a
transmembrane protein 181A
chr3_-_117360876 2.724 ENSMUST00000061071.8
D3Bwg0562e
DNA segment, Chr 3, Brigham & Women's Genetics 0562 expressed
chrX_+_73064787 2.520 ENSMUST00000060418.6
Pnma3
paraneoplastic antigen MA3
chr16_-_57231434 2.472 ENSMUST00000023431.6
Tbc1d23
TBC1 domain family, member 23
chr15_-_101850778 2.091 ENSMUST00000023790.3
Krt1
keratin 1
chr17_-_6477102 2.046 ENSMUST00000167717.2
Tmem181b-ps
transmembrane protein 181B, pseudogene
chr1_+_178529113 1.997 ENSMUST00000161017.1
Kif26b
kinesin family member 26B
chr15_-_43869993 1.973 ENSMUST00000067469.4
Tmem74
transmembrane protein 74
chr16_-_45408955 1.929 ENSMUST00000163230.1
Cd200
CD200 antigen
chr18_+_69346143 1.919 ENSMUST00000114980.1
Tcf4
transcription factor 4
chr1_-_189922338 1.902 ENSMUST00000027897.7
Smyd2
SET and MYND domain containing 2
chr11_-_95309557 1.684 ENSMUST00000092766.5
ENSMUST00000072621.5
Kat7

K(lysine) acetyltransferase 7

chr11_-_115628260 1.681 ENSMUST00000178003.1
Slc25a19
solute carrier family 25 (mitochondrial thiamine pyrophosphate carrier), member 19
chr11_-_115627948 1.672 ENSMUST00000154623.1
ENSMUST00000106503.3
ENSMUST00000141614.1
Slc25a19


solute carrier family 25 (mitochondrial thiamine pyrophosphate carrier), member 19


chr11_-_115628125 1.617 ENSMUST00000155709.1
ENSMUST00000021089.4
Slc25a19

solute carrier family 25 (mitochondrial thiamine pyrophosphate carrier), member 19

chr6_+_96115249 1.580 ENSMUST00000075080.5
Fam19a1
family with sequence similarity 19, member A1
chr17_+_8283762 1.548 ENSMUST00000155364.1
ENSMUST00000046754.8
ENSMUST00000124023.1
Mpc1


mitochondrial pyruvate carrier 1


chr15_-_77970750 1.450 ENSMUST00000100484.4
Eif3d
eukaryotic translation initiation factor 3, subunit D
chr18_-_43393346 1.313 ENSMUST00000025379.7
Dpysl3
dihydropyrimidinase-like 3
chrX_+_41401128 1.297 ENSMUST00000115103.2
Gria3
glutamate receptor, ionotropic, AMPA3 (alpha 3)
chr4_+_130913120 1.276 ENSMUST00000151698.1
Laptm5
lysosomal-associated protein transmembrane 5
chr13_+_109685994 1.260 ENSMUST00000074103.5
Pde4d
phosphodiesterase 4D, cAMP specific
chr4_+_130913264 1.218 ENSMUST00000156225.1
ENSMUST00000156742.1
Laptm5

lysosomal-associated protein transmembrane 5

chr3_+_66219909 1.109 ENSMUST00000029421.5
Ptx3
pentraxin related gene
chr14_+_27622433 1.101 ENSMUST00000090302.5
Erc2
ELKS/RAB6-interacting/CAST family member 2
chr8_+_25720054 1.083 ENSMUST00000068916.8
ENSMUST00000139836.1
Ppapdc1b

phosphatidic acid phosphatase type 2 domain containing 1B

chr13_+_65512678 1.028 ENSMUST00000081471.2
Gm10139
predicted gene 10139
chr6_+_40325471 0.977 ENSMUST00000031977.8
Agk
acylglycerol kinase
chr16_-_74411776 0.954 ENSMUST00000116586.2
Robo2
roundabout homolog 2 (Drosophila)
chr4_+_108328136 0.931 ENSMUST00000131656.1
Selrc1
Sel1 repeat containing 1
chr16_+_75592844 0.925 ENSMUST00000114249.1
ENSMUST00000046378.7
ENSMUST00000114253.1
Rbm11


RNA binding motif protein 11


chr6_-_55681257 0.882 ENSMUST00000044767.8
Neurod6
neurogenic differentiation 6
chr11_-_30986326 0.871 ENSMUST00000020553.4
ENSMUST00000101394.4
Chac2

ChaC, cation transport regulator 2

chr9_-_55919605 0.864 ENSMUST00000037408.8
Scaper
S phase cyclin A-associated protein in the ER
chrX_+_41401304 0.853 ENSMUST00000076349.5
Gria3
glutamate receptor, ionotropic, AMPA3 (alpha 3)
chr19_+_58943413 0.807 ENSMUST00000054280.6
Eno4
enolase 4
chr4_-_129378116 0.805 ENSMUST00000030610.2
Zbtb8a
zinc finger and BTB domain containing 8a
chr12_+_78226627 0.794 ENSMUST00000110388.2
ENSMUST00000052472.4
Gphn

gephyrin

chr1_-_93101825 0.785 ENSMUST00000112958.2
Kif1a
kinesin family member 1A
chr3_+_129532386 0.775 ENSMUST00000071402.2
Elovl6
ELOVL family member 6, elongation of long chain fatty acids (yeast)
chr12_-_23780265 0.745 ENSMUST00000072014.4
Gm10330
predicted gene 10330
chr7_-_73537621 0.734 ENSMUST00000172704.1
Chd2
chromodomain helicase DNA binding protein 2
chr13_-_54749849 0.726 ENSMUST00000135343.1
Gprin1
G protein-regulated inducer of neurite outgrowth 1
chr11_-_62457772 0.700 ENSMUST00000127471.2
Ncor1
nuclear receptor co-repressor 1
chr12_-_27160311 0.687 ENSMUST00000182473.1
ENSMUST00000177636.1
ENSMUST00000183238.1
Gm9866


predicted gene 9866


chr10_+_90071095 0.684 ENSMUST00000183109.1
Anks1b
ankyrin repeat and sterile alpha motif domain containing 1B
chr13_-_12464925 0.670 ENSMUST00000124888.1
Lgals8
lectin, galactose binding, soluble 8
chr8_+_104250925 0.650 ENSMUST00000098464.4
Cklf
chemokine-like factor
chr6_+_149141513 0.630 ENSMUST00000047531.9
ENSMUST00000179873.1
ENSMUST00000111548.1
ENSMUST00000111547.1
ENSMUST00000134306.1
Mettl20




methyltransferase like 20




chr7_+_4460687 0.614 ENSMUST00000167298.1
ENSMUST00000171445.1
Eps8l1

EPS8-like 1

chr11_+_82045705 0.558 ENSMUST00000021011.2
Ccl7
chemokine (C-C motif) ligand 7
chr4_+_102741287 0.537 ENSMUST00000097948.2
Sgip1
SH3-domain GRB2-like (endophilin) interacting protein 1
chr7_+_126649297 0.536 ENSMUST00000032956.8
Ccdc101
coiled-coil domain containing 101
chr16_+_87354185 0.527 ENSMUST00000054442.4
ENSMUST00000118310.1
ENSMUST00000120284.1
ENSMUST00000118115.1
N6amt1



N-6 adenine-specific DNA methyltransferase 1 (putative)



chr11_-_62789402 0.492 ENSMUST00000108705.1
Zfp286
zinc finger protein 286
chr13_-_99344652 0.483 ENSMUST00000022153.6
Ptcd2
pentatricopeptide repeat domain 2
chr19_-_7483212 0.469 ENSMUST00000088169.5
Rtn3
reticulon 3
chr6_+_149141638 0.467 ENSMUST00000166416.1
ENSMUST00000111551.1
Mettl20

methyltransferase like 20

chr12_-_20900867 0.462 ENSMUST00000079237.5
Zfp125
zinc finger protein 125
chr11_+_3963970 0.461 ENSMUST00000020705.4
ENSMUST00000109985.1
Pes1

pescadillo homolog 1, containing BRCT domain (zebrafish)

chr6_-_29216277 0.458 ENSMUST00000162215.1
Impdh1
inosine 5'-phosphate dehydrogenase 1
chr17_-_46674255 0.450 ENSMUST00000024766.6
Rrp36
ribosomal RNA processing 36 homolog (S. cerevisiae)
chr2_+_166805506 0.434 ENSMUST00000099078.3
Arfgef2
ADP-ribosylation factor guanine nucleotide-exchange factor 2 (brefeldin A-inhibited)
chr18_+_37333853 0.432 ENSMUST00000061717.2
Pcdhb6
protocadherin beta 6
chr18_+_37655891 0.425 ENSMUST00000097608.2
3222401L13Rik
RIKEN cDNA 3222401L13 gene
chr14_-_104522615 0.423 ENSMUST00000022716.2
Rnf219
ring finger protein 219
chr19_-_46338632 0.420 ENSMUST00000051234.8
ENSMUST00000167861.1
Cuedc2

CUE domain containing 2

chr6_-_29216301 0.406 ENSMUST00000162739.1
ENSMUST00000162099.1
ENSMUST00000159124.1
Impdh1


inosine 5'-phosphate dehydrogenase 1


chr7_-_126649556 0.405 ENSMUST00000084587.1
2510046G10Rik
RIKEN cDNA 2510046G10 gene
chr8_+_31150307 0.395 ENSMUST00000098842.2
Tti2
TELO2 interacting protein 2
chr11_-_62789445 0.380 ENSMUST00000054654.6
Zfp286
zinc finger protein 286
chr3_+_79885930 0.380 ENSMUST00000029567.8
Fam198b
family with sequence similarity 198, member B
chr13_-_66851513 0.373 ENSMUST00000169322.1
Gm17404
predicted gene, 17404
chr8_+_124023394 0.366 ENSMUST00000034457.8
Urb2
URB2 ribosome biogenesis 2 homolog (S. cerevisiae)
chr13_+_98263105 0.365 ENSMUST00000150916.1
Ankra2
ankyrin repeat, family A (RFXANK-like), 2
chr13_+_98263242 0.341 ENSMUST00000022164.8
ENSMUST00000150352.1
Ankra2

ankyrin repeat, family A (RFXANK-like), 2

chr2_-_104712122 0.332 ENSMUST00000111118.1
ENSMUST00000028597.3
Tcp11l1

t-complex 11 like 1

chr10_-_67912620 0.328 ENSMUST00000064656.7
Zfp365
zinc finger protein 365
chr3_+_145576196 0.323 ENSMUST00000098534.4
Znhit6
zinc finger, HIT type 6
chr13_-_98262946 0.314 ENSMUST00000040972.2
Utp15
UTP15, U3 small nucleolar ribonucleoprotein, homolog (yeast)
chr13_+_98263187 0.314 ENSMUST00000091356.3
ENSMUST00000123924.1
Ankra2

ankyrin repeat, family A (RFXANK-like), 2

chr16_+_23224724 0.312 ENSMUST00000023601.7
St6gal1
beta galactoside alpha 2,6 sialyltransferase 1
chr8_+_33653238 0.307 ENSMUST00000033992.8
Gsr
glutathione reductase
chr6_-_87809757 0.289 ENSMUST00000032134.7
Rab43
RAB43, member RAS oncogene family
chr4_-_135987182 0.278 ENSMUST00000105851.2
Pithd1
PITH (C-terminal proteasome-interacting domain of thioredoxin-like) domain containing 1
chr11_-_72267141 0.264 ENSMUST00000137701.1
Slc13a5
solute carrier family 13 (sodium-dependent citrate transporter), member 5
chr5_-_143292356 0.261 ENSMUST00000180336.1
Zfp853
zinc finger protein 853
chr5_-_123666682 0.258 ENSMUST00000149410.1
Clip1
CAP-GLY domain containing linker protein 1
chr13_+_58281183 0.247 ENSMUST00000180882.1
ENSMUST00000180452.1
Gm26555

predicted gene, 26555

chr2_-_120970706 0.228 ENSMUST00000028728.5
Ubr1
ubiquitin protein ligase E3 component n-recognin 1
chr5_-_73256555 0.226 ENSMUST00000101127.5
ENSMUST00000171179.1
Fryl
Fryl
furry homolog-like (Drosophila)
furry homolog-like (Drosophila)
chr5_-_116024475 0.206 ENSMUST00000111999.1
Prkab1
protein kinase, AMP-activated, beta 1 non-catalytic subunit
chr6_-_118455475 0.189 ENSMUST00000161519.1
ENSMUST00000069292.7
Zfp248

zinc finger protein 248

chr11_+_62458414 0.182 ENSMUST00000014389.5
Pigl
phosphatidylinositol glycan anchor biosynthesis, class L
chr8_+_105225145 0.179 ENSMUST00000034361.3
D230025D16Rik
RIKEN cDNA D230025D16 gene
chr5_+_32611171 0.176 ENSMUST00000072311.6
ENSMUST00000168707.2
Yes1

Yamaguchi sarcoma viral (v-yes) oncogene homolog 1

chr17_+_8182247 0.170 ENSMUST00000161898.1
Fgfr1op
Fgfr1 oncogene partner
chr14_+_49172202 0.166 ENSMUST00000153488.1
Naa30
N(alpha)-acetyltransferase 30, NatC catalytic subunit
chr19_-_4012656 0.127 ENSMUST00000134479.1
ENSMUST00000128787.1
ENSMUST00000133474.1
ENSMUST00000136921.1
ENSMUST00000042497.7
Ndufv1




NADH dehydrogenase (ubiquinone) flavoprotein 1




chr10_-_120979327 0.109 ENSMUST00000119944.1
ENSMUST00000119093.1
Lemd3

LEM domain containing 3

chr12_+_59066908 0.107 ENSMUST00000021381.4
Pnn
pinin
chr14_-_34503323 0.102 ENSMUST00000171343.1
Bmpr1a
bone morphogenetic protein receptor, type 1A
chrX_+_74270812 0.101 ENSMUST00000008826.7
ENSMUST00000151702.1
ENSMUST00000074085.5
ENSMUST00000135690.1
Rpl10



ribosomal protein L10



chr15_+_85510812 0.095 ENSMUST00000079690.2
Gm4825
predicted pseudogene 4825
chr9_-_75441652 0.095 ENSMUST00000181896.1
A130057D12Rik
RIKEN cDNA A130057D12 gene
chr13_-_66852017 0.084 ENSMUST00000059329.6
Gm17449
predicted gene, 17449
chr9_-_106247730 0.076 ENSMUST00000112524.2
ENSMUST00000074082.6
Alas1

aminolevulinic acid synthase 1

chr6_+_42286709 0.075 ENSMUST00000163936.1
Clcn1
chloride channel 1
chr17_+_22361453 0.052 ENSMUST00000149699.1
ENSMUST00000088765.2
ENSMUST00000072477.4
ENSMUST00000121315.1
Zfp758



zinc finger protein 758



chr5_-_116024452 0.052 ENSMUST00000031486.7
Prkab1
protein kinase, AMP-activated, beta 1 non-catalytic subunit
chr9_+_44407629 0.048 ENSMUST00000080300.7
Rps25
ribosomal protein S25
chr7_+_43634718 0.038 ENSMUST00000032663.8
Ceacam18
carcinoembryonic antigen-related cell adhesion molecule 18
chr17_-_24455265 0.037 ENSMUST00000056032.7
E4f1
E4F transcription factor 1
chr16_-_23225334 0.027 ENSMUST00000055369.4
BC106179
cDNA sequence BC106179
chr4_-_135986917 0.026 ENSMUST00000123404.1
Pithd1
PITH (C-terminal proteasome-interacting domain of thioredoxin-like) domain containing 1
chr19_-_7341848 0.025 ENSMUST00000171393.1
Mark2
MAP/microtubule affinity-regulating kinase 2
chr6_+_42286676 0.020 ENSMUST00000031894.6
Clcn1
chloride channel 1
chr5_-_20951769 0.020 ENSMUST00000036489.5
Rsbn1l
round spermatid basic protein 1-like
chr9_+_37613806 0.015 ENSMUST00000002007.3
Siae
sialic acid acetylesterase

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
1.7 5.0 GO:0030974 thiamine pyrophosphate transport(GO:0030974)
1.2 6.0 GO:0042636 negative regulation of hair cycle(GO:0042636) progesterone secretion(GO:0042701) negative regulation of hair follicle development(GO:0051799) positive regulation of ovulation(GO:0060279)
1.2 7.0 GO:0042045 epithelial fluid transport(GO:0042045)
0.7 2.0 GO:0072092 ureteric bud invasion(GO:0072092) metanephric renal vesicle formation(GO:0072093)
0.6 1.9 GO:0043031 negative regulation of macrophage activation(GO:0043031)
0.6 1.7 GO:0072720 response to sorbitol(GO:0072708) response to dithiothreitol(GO:0072720)
0.5 8.2 GO:0021902 commitment of neuronal cell to specific neuron type in forebrain(GO:0021902)
0.5 4.0 GO:0070314 G1 to G0 transition(GO:0070314)
0.5 1.4 GO:0002191 cap-dependent translational initiation(GO:0002191)
0.5 2.9 GO:0009405 pathogenesis(GO:0009405)
0.4 3.4 GO:0038028 insulin receptor signaling pathway via phosphatidylinositol 3-kinase(GO:0038028)
0.4 1.5 GO:1901475 pyruvate transmembrane transport(GO:1901475)
0.3 1.0 GO:0050925 negative regulation of negative chemotaxis(GO:0050925)
0.3 2.1 GO:0001867 complement activation, lectin pathway(GO:0001867)
0.3 8.5 GO:0022401 desensitization of G-protein coupled receptor protein signaling pathway(GO:0002029) negative adaptation of signaling pathway(GO:0022401)
0.2 1.9 GO:0018026 peptidyl-lysine monomethylation(GO:0018026)
0.2 1.1 GO:0052428 modulation of molecular function in other organism(GO:0044359) negative regulation of molecular function in other organism(GO:0044362) negative regulation of molecular function in other organism involved in symbiotic interaction(GO:0052204) modulation of molecular function in other organism involved in symbiotic interaction(GO:0052205) negative regulation by host of symbiont molecular function(GO:0052405) modification by host of symbiont molecular function(GO:0052428)
0.2 0.9 GO:0006751 glutathione catabolic process(GO:0006751)
0.2 0.7 GO:0072362 regulation of glycolytic process by negative regulation of transcription from RNA polymerase II promoter(GO:0072362)
0.2 1.9 GO:0042118 endothelial cell activation(GO:0042118)
0.2 0.9 GO:0006177 GMP biosynthetic process(GO:0006177)
0.2 0.8 GO:0006777 Mo-molybdopterin cofactor biosynthetic process(GO:0006777) Mo-molybdopterin cofactor metabolic process(GO:0019720)
0.2 4.1 GO:0030903 notochord development(GO:0030903)
0.1 0.7 GO:0002317 plasma cell differentiation(GO:0002317)
0.1 0.3 GO:0033566 gamma-tubulin complex localization(GO:0033566)
0.1 0.4 GO:0010936 negative regulation of macrophage cytokine production(GO:0010936)
0.1 0.6 GO:1900029 positive regulation of ruffle assembly(GO:1900029)
0.1 4.5 GO:1900026 positive regulation of substrate adhesion-dependent cell spreading(GO:1900026)
0.1 1.3 GO:1901898 regulation of cell communication by electrical coupling involved in cardiac conduction(GO:1901844) negative regulation of relaxation of cardiac muscle(GO:1901898)
0.1 0.3 GO:0035526 retrograde transport, plasma membrane to Golgi(GO:0035526)
0.1 0.5 GO:0071787 endoplasmic reticulum tubular network assembly(GO:0071787)
0.1 0.3 GO:2000110 protein sialylation(GO:1990743) negative regulation of macrophage apoptotic process(GO:2000110)
0.1 0.8 GO:0019368 fatty acid elongation, saturated fatty acid(GO:0019367) fatty acid elongation, unsaturated fatty acid(GO:0019368) fatty acid elongation, monounsaturated fatty acid(GO:0034625) fatty acid elongation, polyunsaturated fatty acid(GO:0034626)
0.1 0.6 GO:0071361 cellular response to ethanol(GO:0071361)
0.1 0.3 GO:0015744 succinate transport(GO:0015744)
0.1 1.3 GO:0051764 actin crosslink formation(GO:0051764)
0.1 0.3 GO:0044861 protein transport into plasma membrane raft(GO:0044861)
0.1 0.5 GO:2000253 positive regulation of feeding behavior(GO:2000253)
0.1 0.2 GO:0071596 ubiquitin-dependent protein catabolic process via the N-end rule pathway(GO:0071596)
0.1 0.7 GO:1900383 regulation of synaptic plasticity by receptor localization to synapse(GO:1900383)
0.1 0.8 GO:0022027 interkinetic nuclear migration(GO:0022027)
0.1 0.3 GO:0048254 snoRNA localization(GO:0048254)
0.1 0.3 GO:0090070 positive regulation of ribosome biogenesis(GO:0090070) positive regulation of rRNA processing(GO:2000234)
0.1 0.5 GO:0007000 nucleolus organization(GO:0007000)
0.1 2.2 GO:0001919 regulation of receptor recycling(GO:0001919)
0.0 0.3 GO:0035878 nail development(GO:0035878)
0.0 0.9 GO:0021542 dentate gyrus development(GO:0021542)
0.0 0.7 GO:0060218 hematopoietic stem cell differentiation(GO:0060218)
0.0 0.4 GO:0001881 receptor recycling(GO:0001881)
0.0 0.1 GO:0021998 neural plate mediolateral regionalization(GO:0021998) mesoderm structural organization(GO:0048338) paraxial mesoderm structural organization(GO:0048352) positive regulation of cardiac ventricle development(GO:1904414)
0.0 0.2 GO:0090527 actin filament reorganization(GO:0090527)
0.0 0.2 GO:0017196 N-terminal peptidyl-methionine acetylation(GO:0017196)
0.0 0.1 GO:0070197 meiotic telomere tethering at nuclear periphery(GO:0044821) meiotic attachment of telomere to nuclear envelope(GO:0070197) chromosome attachment to the nuclear envelope(GO:0097240)
0.0 0.8 GO:0046834 lipid phosphorylation(GO:0046834)
0.0 0.9 GO:0000381 regulation of alternative mRNA splicing, via spliceosome(GO:0000381)
0.0 1.4 GO:0032755 positive regulation of interleukin-6 production(GO:0032755)
0.0 0.5 GO:0000469 cleavage involved in rRNA processing(GO:0000469)
0.0 0.4 GO:0048026 positive regulation of mRNA splicing, via spliceosome(GO:0048026)
0.0 0.7 GO:0048246 macrophage chemotaxis(GO:0048246)
0.0 0.2 GO:0036120 response to platelet-derived growth factor(GO:0036119) cellular response to platelet-derived growth factor stimulus(GO:0036120)
0.0 0.8 GO:0030317 sperm motility(GO:0030317)
0.0 3.1 GO:0031032 actomyosin structure organization(GO:0031032)
0.0 0.4 GO:0009988 cell-cell recognition(GO:0009988)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
2.3 7.0 GO:0031088 platelet dense granule membrane(GO:0031088)
2.0 6.0 GO:0043512 inhibin A complex(GO:0043512)
0.4 2.1 GO:0001533 cornified envelope(GO:0001533)
0.3 4.5 GO:0042581 specific granule(GO:0042581)
0.2 4.0 GO:0031045 dense core granule(GO:0031045)
0.2 6.5 GO:0031305 integral component of mitochondrial inner membrane(GO:0031305)
0.2 1.0 GO:1990393 3M complex(GO:1990393)
0.2 1.4 GO:0071541 eukaryotic translation initiation factor 3 complex, eIF3m(GO:0071541)
0.1 2.2 GO:0043083 synaptic cleft(GO:0043083)
0.1 0.4 GO:0032280 symmetric synapse(GO:0032280)
0.1 0.8 GO:0000015 phosphopyruvate hydratase complex(GO:0000015)
0.1 8.9 GO:0000118 histone deacetylase complex(GO:0000118)
0.1 0.2 GO:0030427 site of polarized growth(GO:0030427)
0.1 0.2 GO:0031417 NatC complex(GO:0031417)
0.0 0.5 GO:0070545 PeBoW complex(GO:0070545)
0.0 0.3 GO:0044352 pinosome(GO:0044352) macropinosome(GO:0044354)
0.0 0.5 GO:0030122 AP-2 adaptor complex(GO:0030122)
0.0 0.8 GO:0060077 inhibitory synapse(GO:0060077)
0.0 0.3 GO:0000138 Golgi trans cisterna(GO:0000138)
0.0 1.3 GO:0005891 voltage-gated calcium channel complex(GO:0005891)
0.0 0.3 GO:0070761 pre-snoRNP complex(GO:0070761)
0.0 1.0 GO:0030673 axolemma(GO:0030673)
0.0 1.3 GO:0031941 filamentous actin(GO:0031941)
0.0 1.1 GO:0048786 presynaptic active zone(GO:0048786)
0.0 1.7 GO:0000123 histone acetyltransferase complex(GO:0000123)
0.0 1.9 GO:0005913 cell-cell adherens junction(GO:0005913)
0.0 0.3 GO:0000930 gamma-tubulin complex(GO:0000930)
0.0 0.3 GO:0031588 nucleotide-activated protein kinase complex(GO:0031588)
0.0 0.5 GO:0030686 90S preribosome(GO:0030686)
0.0 0.1 GO:0030057 desmosome(GO:0030057)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
2.8 8.5 GO:0030549 acetylcholine receptor activator activity(GO:0030549)
2.3 7.0 GO:0005220 inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0005220)
1.0 6.0 GO:0070699 type II activin receptor binding(GO:0070699)
0.8 5.0 GO:0015234 thiamine transmembrane transporter activity(GO:0015234)
0.5 1.9 GO:0001011 transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087)
0.4 1.5 GO:0050833 pyruvate transmembrane transporter activity(GO:0050833)
0.3 1.0 GO:0001729 ceramide kinase activity(GO:0001729)
0.3 1.9 GO:0046975 histone methyltransferase activity (H3-K36 specific)(GO:0046975)
0.3 2.2 GO:0004971 AMPA glutamate receptor activity(GO:0004971)
0.2 2.9 GO:0015643 toxic substance binding(GO:0015643)
0.2 0.9 GO:0003938 IMP dehydrogenase activity(GO:0003938)
0.2 0.8 GO:0043546 molybdopterin cofactor binding(GO:0043546)
0.2 0.9 GO:0003839 gamma-glutamylcyclotransferase activity(GO:0003839)
0.2 1.1 GO:0001849 complement component C1q binding(GO:0001849)
0.1 1.3 GO:0035374 chondroitin sulfate binding(GO:0035374)
0.1 0.6 GO:0031727 CCR2 chemokine receptor binding(GO:0031727)
0.1 1.7 GO:0003688 DNA replication origin binding(GO:0003688)
0.1 3.4 GO:0043539 insulin-like growth factor receptor binding(GO:0005159) protein serine/threonine kinase activator activity(GO:0043539)
0.1 1.4 GO:0000339 RNA cap binding(GO:0000339)
0.1 1.0 GO:0008046 axon guidance receptor activity(GO:0008046)
0.1 0.3 GO:0015038 glutathione disulfide oxidoreductase activity(GO:0015038)
0.1 4.1 GO:0005504 fatty acid binding(GO:0005504)
0.1 0.8 GO:0004634 phosphopyruvate hydratase activity(GO:0004634)
0.1 0.3 GO:0017153 sodium:dicarboxylate symporter activity(GO:0017153)
0.1 0.7 GO:0035033 histone deacetylase regulator activity(GO:0035033)
0.1 0.8 GO:0009922 fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338)
0.1 0.3 GO:0003835 beta-galactoside alpha-2,6-sialyltransferase activity(GO:0003835)
0.0 0.9 GO:0008266 poly(U) RNA binding(GO:0008266)
0.0 0.2 GO:0030292 protein tyrosine kinase inhibitor activity(GO:0030292)
0.0 0.3 GO:0001094 TFIID-class transcription factor binding(GO:0001094)
0.0 1.3 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
0.0 0.2 GO:0070728 leucine binding(GO:0070728)
0.0 0.6 GO:0042608 T cell receptor binding(GO:0042608)
0.0 1.0 GO:0050750 low-density lipoprotein particle receptor binding(GO:0050750)
0.0 0.3 GO:0004679 AMP-activated protein kinase activity(GO:0004679)
0.0 0.1 GO:0016748 succinyltransferase activity(GO:0016748)
0.0 0.4 GO:0050811 GABA receptor binding(GO:0050811)
0.0 0.7 GO:0008009 chemokine activity(GO:0008009)
0.0 0.3 GO:0051010 microtubule plus-end binding(GO:0051010)
0.0 0.7 GO:0046875 ephrin receptor binding(GO:0046875)
0.0 0.1 GO:0098821 BMP receptor activity(GO:0098821)
0.0 2.8 GO:0030246 carbohydrate binding(GO:0030246)
0.0 1.3 GO:0030165 PDZ domain binding(GO:0030165)
0.0 0.2 GO:0004596 peptide alpha-N-acetyltransferase activity(GO:0004596)
0.0 6.0 GO:0050839 cell adhesion molecule binding(GO:0050839)
0.0 0.1 GO:0010181 FMN binding(GO:0010181)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 4.7 ST_WNT_CA2_CYCLIC_GMP_PATHWAY Wnt/Ca2+/cyclic GMP signaling.
0.2 6.0 PID_ALK1_PATHWAY ALK1 signaling events
0.1 3.4 PID_AJDISS_2PATHWAY Posttranslational regulation of adherens junction stability and dissassembly
0.0 1.1 ST_MYOCYTE_AD_PATHWAY Myocyte Adrenergic Pathway is a specific case of the generalized Adrenergic Pathway.
0.0 4.0 PID_BETA_CATENIN_NUC_PATHWAY Regulation of nuclear beta catenin signaling and target gene transcription
0.0 1.7 PID_AR_TF_PATHWAY Regulation of Androgen receptor activity
0.0 1.0 PID_HDAC_CLASSII_PATHWAY Signaling events mediated by HDAC Class II
0.0 1.3 PID_P53_REGULATION_PATHWAY p53 pathway
0.0 0.7 PID_HDAC_CLASSI_PATHWAY Signaling events mediated by HDAC Class I

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
1.5 6.0 REACTOME_GLYCOPROTEIN_HORMONES Genes involved in Glycoprotein hormones
0.2 3.4 REACTOME_REGULATION_OF_INSULIN_LIKE_GROWTH_FACTOR_IGF_ACTIVITY_BY_INSULIN_LIKE_GROWTH_FACTOR_BINDING_PROTEINS_IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.1 2.2 REACTOME_TRAFFICKING_OF_GLUR2_CONTAINING_AMPA_RECEPTORS Genes involved in Trafficking of GluR2-containing AMPA receptors
0.1 1.3 REACTOME_CRMPS_IN_SEMA3A_SIGNALING Genes involved in CRMPs in Sema3A signaling
0.1 0.9 REACTOME_PURINE_RIBONUCLEOSIDE_MONOPHOSPHATE_BIOSYNTHESIS Genes involved in Purine ribonucleoside monophosphate biosynthesis
0.1 1.9 REACTOME_MYOGENESIS Genes involved in Myogenesis
0.0 0.3 REACTOME_TERMINATION_OF_O_GLYCAN_BIOSYNTHESIS Genes involved in Termination of O-glycan biosynthesis
0.0 1.3 REACTOME_DARPP_32_EVENTS Genes involved in DARPP-32 events
0.0 0.3 REACTOME_BILE_SALT_AND_ORGANIC_ANION_SLC_TRANSPORTERS Genes involved in Bile salt and organic anion SLC transporters
0.0 0.8 REACTOME_SYNTHESIS_OF_VERY_LONG_CHAIN_FATTY_ACYL_COAS Genes involved in Synthesis of very long-chain fatty acyl-CoAs
0.0 1.5 REACTOME_FORMATION_OF_THE_TERNARY_COMPLEX_AND_SUBSEQUENTLY_THE_43S_COMPLEX Genes involved in Formation of the ternary complex, and subsequently, the 43S complex
0.0 1.0 REACTOME_SIGNALING_BY_ROBO_RECEPTOR Genes involved in Signaling by Robo receptor
0.0 0.7 REACTOME_CIRCADIAN_REPRESSION_OF_EXPRESSION_BY_REV_ERBA Genes involved in Circadian Repression of Expression by REV-ERBA
0.0 0.6 REACTOME_CHEMOKINE_RECEPTORS_BIND_CHEMOKINES Genes involved in Chemokine receptors bind chemokines
0.0 0.3 REACTOME_REGULATION_OF_RHEB_GTPASE_ACTIVITY_BY_AMPK Genes involved in Regulation of Rheb GTPase activity by AMPK
0.0 0.8 REACTOME_METABOLISM_OF_VITAMINS_AND_COFACTORS Genes involved in Metabolism of vitamins and cofactors
0.0 0.2 REACTOME_PECAM1_INTERACTIONS Genes involved in PECAM1 interactions
0.0 0.3 REACTOME_SYNTHESIS_AND_INTERCONVERSION_OF_NUCLEOTIDE_DI_AND_TRIPHOSPHATES Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.0 0.4 REACTOME_ASSOCIATION_OF_TRIC_CCT_WITH_TARGET_PROTEINS_DURING_BIOSYNTHESIS Genes involved in Association of TriC/CCT with target proteins during biosynthesis