Motif ID: Hoxa13
Z-value: 0.873
Transcription factors associated with Hoxa13:
Gene Symbol | Entrez ID | Gene Name |
---|---|---|
Hoxa13 | ENSMUSG00000038203.12 | Hoxa13 |
Top targets:
Gene overrepresentation in biological_process category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
1.2 | 3.6 | GO:1903225 | negative regulation of endodermal cell differentiation(GO:1903225) |
0.8 | 2.5 | GO:0061349 | Wnt signaling pathway involved in digestive tract morphogenesis(GO:0044333) hypophysis morphogenesis(GO:0048850) cervix development(GO:0060067) planar cell polarity pathway involved in outflow tract morphogenesis(GO:0061347) planar cell polarity pathway involved in ventricular septum morphogenesis(GO:0061348) planar cell polarity pathway involved in cardiac right atrium morphogenesis(GO:0061349) planar cell polarity pathway involved in cardiac muscle tissue morphogenesis(GO:0061350) planar cell polarity pathway involved in pericardium morphogenesis(GO:0061354) |
0.6 | 1.9 | GO:0044208 | 'de novo' AMP biosynthetic process(GO:0044208) |
0.6 | 0.6 | GO:0003134 | BMP signaling pathway involved in heart induction(GO:0003130) endodermal-mesodermal cell signaling(GO:0003133) endodermal-mesodermal cell signaling involved in heart induction(GO:0003134) |
0.5 | 1.0 | GO:0061341 | non-canonical Wnt signaling pathway involved in heart development(GO:0061341) planar cell polarity pathway involved in heart morphogenesis(GO:0061346) |
0.5 | 2.4 | GO:0071879 | positive regulation of adrenergic receptor signaling pathway(GO:0071879) |
0.5 | 1.4 | GO:1903490 | regulation of cytokinetic process(GO:0032954) regulation of mitotic cytokinetic process(GO:1903436) positive regulation of mitotic cytokinetic process(GO:1903438) positive regulation of mitotic cytokinesis(GO:1903490) |
0.5 | 1.9 | GO:0035609 | C-terminal protein deglutamylation(GO:0035609) |
0.4 | 2.6 | GO:0030913 | paranodal junction assembly(GO:0030913) |
0.4 | 1.3 | GO:0036388 | pre-replicative complex assembly involved in nuclear cell cycle DNA replication(GO:0006267) pre-replicative complex assembly(GO:0036388) DNA replication preinitiation complex assembly(GO:0071163) pre-replicative complex assembly involved in cell cycle DNA replication(GO:1902299) |
0.4 | 0.9 | GO:0003347 | epicardial cell to mesenchymal cell transition(GO:0003347) |
0.4 | 2.0 | GO:0046864 | retinol transport(GO:0034633) isoprenoid transport(GO:0046864) terpenoid transport(GO:0046865) alveolar primary septum development(GO:0061143) |
0.4 | 6.5 | GO:0048387 | negative regulation of retinoic acid receptor signaling pathway(GO:0048387) |
0.4 | 1.2 | GO:0014809 | regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion(GO:0014809) |
0.4 | 1.1 | GO:1904211 | membrane protein proteolysis involved in retrograde protein transport, ER to cytosol(GO:1904211) |
0.4 | 2.9 | GO:0090336 | positive regulation of brown fat cell differentiation(GO:0090336) |
0.3 | 1.0 | GO:0071918 | urea transmembrane transport(GO:0071918) |
0.3 | 1.7 | GO:0035262 | gonad morphogenesis(GO:0035262) |
0.3 | 1.7 | GO:0035063 | nuclear speck organization(GO:0035063) |
0.3 | 1.8 | GO:0000707 | meiotic DNA recombinase assembly(GO:0000707) |
0.3 | 1.2 | GO:2000048 | negative regulation of cell-cell adhesion mediated by cadherin(GO:2000048) |
0.3 | 1.7 | GO:0046502 | uroporphyrinogen III metabolic process(GO:0046502) |
0.3 | 1.2 | GO:0070269 | pyroptosis(GO:0070269) |
0.3 | 2.0 | GO:0035754 | B cell chemotaxis(GO:0035754) |
0.3 | 7.2 | GO:0032967 | positive regulation of collagen biosynthetic process(GO:0032967) |
0.3 | 0.8 | GO:0002430 | complement receptor mediated signaling pathway(GO:0002430) GPI anchor release(GO:0006507) |
0.3 | 0.8 | GO:0014877 | response to inactivity(GO:0014854) response to muscle inactivity(GO:0014870) response to muscle inactivity involved in regulation of muscle adaptation(GO:0014877) response to denervation involved in regulation of muscle adaptation(GO:0014894) |
0.3 | 1.1 | GO:1903463 | regulation of mitotic cell cycle DNA replication(GO:1903463) |
0.3 | 0.8 | GO:1901856 | negative regulation of cellular respiration(GO:1901856) |
0.3 | 0.8 | GO:0008594 | photoreceptor cell morphogenesis(GO:0008594) |
0.3 | 1.3 | GO:0002457 | T cell antigen processing and presentation(GO:0002457) |
0.2 | 1.0 | GO:0072362 | regulation of glycolytic process by negative regulation of transcription from RNA polymerase II promoter(GO:0072362) |
0.2 | 5.8 | GO:0040034 | regulation of development, heterochronic(GO:0040034) |
0.2 | 1.4 | GO:0016584 | nucleosome positioning(GO:0016584) |
0.2 | 0.8 | GO:0070537 | histone H2A K63-linked deubiquitination(GO:0070537) |
0.2 | 1.7 | GO:0042538 | hyperosmotic salinity response(GO:0042538) |
0.2 | 3.5 | GO:0097113 | AMPA glutamate receptor clustering(GO:0097113) glutamate receptor clustering(GO:0097688) |
0.2 | 0.9 | GO:0035426 | extracellular matrix-cell signaling(GO:0035426) |
0.2 | 1.3 | GO:0031848 | protection from non-homologous end joining at telomere(GO:0031848) |
0.2 | 0.3 | GO:2000825 | positive regulation of androgen receptor activity(GO:2000825) |
0.2 | 0.6 | GO:0002337 | B-1a B cell differentiation(GO:0002337) |
0.2 | 0.5 | GO:2000097 | negative regulation of lipoprotein metabolic process(GO:0050748) regulation of smooth muscle cell-matrix adhesion(GO:2000097) negative regulation of lymphocyte migration(GO:2000402) |
0.2 | 0.5 | GO:0002314 | germinal center B cell differentiation(GO:0002314) |
0.2 | 1.4 | GO:0001842 | neural fold formation(GO:0001842) |
0.1 | 2.4 | GO:0038063 | collagen-activated tyrosine kinase receptor signaling pathway(GO:0038063) collagen-activated signaling pathway(GO:0038065) |
0.1 | 2.8 | GO:0016339 | calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0016339) |
0.1 | 2.0 | GO:0010216 | maintenance of DNA methylation(GO:0010216) regulation of methylation-dependent chromatin silencing(GO:0090308) |
0.1 | 7.5 | GO:0070303 | negative regulation of stress-activated MAPK cascade(GO:0032873) negative regulation of stress-activated protein kinase signaling cascade(GO:0070303) |
0.1 | 0.4 | GO:2000314 | negative regulation of fibroblast growth factor receptor signaling pathway involved in neural plate anterior/posterior pattern formation(GO:2000314) |
0.1 | 0.4 | GO:0035790 | platelet-derived growth factor receptor-alpha signaling pathway(GO:0035790) |
0.1 | 1.2 | GO:0097475 | motor neuron migration(GO:0097475) |
0.1 | 0.5 | GO:0007352 | zygotic specification of dorsal/ventral axis(GO:0007352) |
0.1 | 1.8 | GO:0000729 | DNA double-strand break processing(GO:0000729) |
0.1 | 0.4 | GO:1903406 | regulation of sodium:potassium-exchanging ATPase activity(GO:1903406) |
0.1 | 1.3 | GO:0048733 | peptidyl-L-cysteine S-palmitoylation(GO:0018230) peptidyl-S-diacylglycerol-L-cysteine biosynthetic process from peptidyl-cysteine(GO:0018231) sebaceous gland development(GO:0048733) |
0.1 | 0.4 | GO:0003274 | tolerance induction to self antigen(GO:0002513) endocardial cushion fusion(GO:0003274) |
0.1 | 0.6 | GO:0071894 | histone H2B conserved C-terminal lysine ubiquitination(GO:0071894) |
0.1 | 3.7 | GO:0035335 | peptidyl-tyrosine dephosphorylation(GO:0035335) |
0.1 | 2.1 | GO:0035493 | SNARE complex assembly(GO:0035493) |
0.1 | 2.3 | GO:0051482 | positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G-protein coupled signaling pathway(GO:0051482) |
0.1 | 1.8 | GO:0071625 | vocalization behavior(GO:0071625) |
0.1 | 0.9 | GO:0006013 | mannose metabolic process(GO:0006013) |
0.1 | 1.0 | GO:0051967 | negative regulation of synaptic transmission, glutamatergic(GO:0051967) |
0.1 | 1.7 | GO:0007379 | segment specification(GO:0007379) |
0.1 | 0.9 | GO:0048102 | autophagic cell death(GO:0048102) |
0.1 | 1.2 | GO:0046697 | decidualization(GO:0046697) |
0.1 | 0.3 | GO:0097051 | establishment of protein localization to endoplasmic reticulum membrane(GO:0097051) |
0.1 | 0.5 | GO:0009405 | pathogenesis(GO:0009405) |
0.1 | 0.2 | GO:0019805 | quinolinate biosynthetic process(GO:0019805) |
0.1 | 0.6 | GO:0010273 | detoxification of copper ion(GO:0010273) stress response to copper ion(GO:1990169) |
0.1 | 1.7 | GO:0047497 | establishment of mitochondrion localization, microtubule-mediated(GO:0034643) mitochondrion transport along microtubule(GO:0047497) |
0.1 | 0.4 | GO:1903566 | positive regulation of protein localization to cilium(GO:1903566) |
0.1 | 0.4 | GO:0042297 | vocal learning(GO:0042297) imitative learning(GO:0098596) learned vocalization behavior or vocal learning(GO:0098598) |
0.1 | 2.6 | GO:0035458 | cellular response to interferon-beta(GO:0035458) |
0.1 | 0.5 | GO:0014816 | skeletal muscle satellite cell differentiation(GO:0014816) |
0.1 | 0.6 | GO:0019227 | neuronal action potential propagation(GO:0019227) action potential propagation(GO:0098870) |
0.1 | 0.8 | GO:0046036 | CTP biosynthetic process(GO:0006241) CTP metabolic process(GO:0046036) |
0.1 | 0.1 | GO:0097680 | double-strand break repair via classical nonhomologous end joining(GO:0097680) |
0.1 | 1.3 | GO:0060252 | positive regulation of glial cell proliferation(GO:0060252) |
0.1 | 0.2 | GO:0000733 | DNA strand renaturation(GO:0000733) |
0.1 | 0.3 | GO:0018242 | protein O-linked glycosylation via serine(GO:0018242) |
0.1 | 0.1 | GO:0035359 | negative regulation of peroxisome proliferator activated receptor signaling pathway(GO:0035359) cell proliferation involved in heart valve development(GO:2000793) |
0.1 | 0.6 | GO:0010839 | negative regulation of keratinocyte proliferation(GO:0010839) |
0.1 | 0.4 | GO:0021869 | forebrain ventricular zone progenitor cell division(GO:0021869) |
0.1 | 1.7 | GO:0007608 | sensory perception of smell(GO:0007608) |
0.1 | 1.7 | GO:0014912 | negative regulation of smooth muscle cell migration(GO:0014912) |
0.1 | 0.1 | GO:0060126 | somatotropin secreting cell differentiation(GO:0060126) |
0.1 | 2.9 | GO:0010501 | RNA secondary structure unwinding(GO:0010501) |
0.1 | 1.5 | GO:0035235 | ionotropic glutamate receptor signaling pathway(GO:0035235) |
0.1 | 0.3 | GO:0002934 | desmosome organization(GO:0002934) |
0.1 | 0.3 | GO:0035878 | nail development(GO:0035878) |
0.1 | 0.9 | GO:0010592 | positive regulation of lamellipodium assembly(GO:0010592) |
0.0 | 0.3 | GO:0018344 | protein geranylgeranylation(GO:0018344) |
0.0 | 3.4 | GO:0046847 | filopodium assembly(GO:0046847) |
0.0 | 0.5 | GO:0060363 | cranial suture morphogenesis(GO:0060363) |
0.0 | 1.3 | GO:0095500 | acetylcholine receptor signaling pathway(GO:0095500) signal transduction involved in cellular response to ammonium ion(GO:1903831) response to acetylcholine(GO:1905144) cellular response to acetylcholine(GO:1905145) |
0.0 | 0.3 | GO:0097428 | protein maturation by iron-sulfur cluster transfer(GO:0097428) |
0.0 | 0.1 | GO:0045006 | DNA deamination(GO:0045006) |
0.0 | 0.7 | GO:0009083 | branched-chain amino acid catabolic process(GO:0009083) |
0.0 | 1.0 | GO:0007214 | gamma-aminobutyric acid signaling pathway(GO:0007214) |
0.0 | 1.6 | GO:0046677 | response to antibiotic(GO:0046677) |
0.0 | 0.5 | GO:0043252 | sodium-independent organic anion transport(GO:0043252) |
0.0 | 0.7 | GO:0043968 | histone H2A acetylation(GO:0043968) |
0.0 | 0.1 | GO:0032792 | positive regulation of translational initiation in response to stress(GO:0032058) negative regulation of CREB transcription factor activity(GO:0032792) |
0.0 | 0.7 | GO:0001886 | endothelial cell morphogenesis(GO:0001886) |
0.0 | 1.1 | GO:0090162 | establishment of epithelial cell polarity(GO:0090162) |
0.0 | 0.2 | GO:0043137 | DNA replication, removal of RNA primer(GO:0043137) |
0.0 | 0.9 | GO:0097120 | receptor localization to synapse(GO:0097120) |
0.0 | 1.5 | GO:0042773 | ATP synthesis coupled electron transport(GO:0042773) |
0.0 | 1.8 | GO:0006749 | glutathione metabolic process(GO:0006749) |
0.0 | 0.2 | GO:0044791 | modulation by host of viral release from host cell(GO:0044789) positive regulation by host of viral release from host cell(GO:0044791) |
0.0 | 1.1 | GO:0000038 | very long-chain fatty acid metabolic process(GO:0000038) |
0.0 | 1.2 | GO:0006506 | GPI anchor biosynthetic process(GO:0006506) |
0.0 | 0.1 | GO:0045896 | regulation of transcription during mitosis(GO:0045896) positive regulation of transcription during mitosis(GO:0045897) |
0.0 | 1.8 | GO:0008543 | fibroblast growth factor receptor signaling pathway(GO:0008543) |
0.0 | 0.5 | GO:0010758 | regulation of macrophage chemotaxis(GO:0010758) |
0.0 | 0.3 | GO:0042118 | endothelial cell activation(GO:0042118) |
0.0 | 0.2 | GO:0009404 | toxin metabolic process(GO:0009404) |
0.0 | 1.0 | GO:0034198 | cellular response to amino acid starvation(GO:0034198) |
0.0 | 0.6 | GO:0060716 | labyrinthine layer blood vessel development(GO:0060716) |
0.0 | 0.8 | GO:0030488 | tRNA methylation(GO:0030488) |
0.0 | 0.6 | GO:0032958 | inositol phosphate biosynthetic process(GO:0032958) |
0.0 | 0.2 | GO:0050957 | equilibrioception(GO:0050957) |
0.0 | 0.1 | GO:0016557 | peroxisome membrane biogenesis(GO:0016557) chaperone-mediated protein transport(GO:0072321) |
0.0 | 0.4 | GO:0006895 | Golgi to endosome transport(GO:0006895) |
0.0 | 0.3 | GO:0007602 | phototransduction(GO:0007602) |
0.0 | 0.2 | GO:0035735 | intraciliary transport involved in cilium morphogenesis(GO:0035735) |
0.0 | 0.1 | GO:0044837 | assembly of actomyosin apparatus involved in cytokinesis(GO:0000912) actomyosin contractile ring assembly(GO:0000915) actomyosin contractile ring organization(GO:0044837) |
0.0 | 0.2 | GO:0006610 | ribosomal protein import into nucleus(GO:0006610) |
0.0 | 0.5 | GO:0001522 | pseudouridine synthesis(GO:0001522) |
0.0 | 0.1 | GO:0032782 | bile acid secretion(GO:0032782) |
0.0 | 1.9 | GO:0043488 | regulation of mRNA stability(GO:0043488) |
0.0 | 0.2 | GO:0015838 | proline transport(GO:0015824) amino-acid betaine transport(GO:0015838) |
0.0 | 0.5 | GO:0097352 | autophagosome maturation(GO:0097352) |
0.0 | 0.3 | GO:0060218 | hematopoietic stem cell differentiation(GO:0060218) |
0.0 | 0.3 | GO:0070816 | phosphorylation of RNA polymerase II C-terminal domain(GO:0070816) |
0.0 | 0.1 | GO:0045409 | negative regulation of interleukin-6 biosynthetic process(GO:0045409) |
0.0 | 0.0 | GO:0090400 | stress-induced premature senescence(GO:0090400) |
0.0 | 0.1 | GO:0048861 | leukemia inhibitory factor signaling pathway(GO:0048861) |
0.0 | 0.4 | GO:0046827 | positive regulation of protein export from nucleus(GO:0046827) |
0.0 | 0.1 | GO:0051451 | myoblast migration(GO:0051451) |
0.0 | 0.3 | GO:0010569 | regulation of double-strand break repair via homologous recombination(GO:0010569) |
0.0 | 0.3 | GO:0015985 | energy coupled proton transport, down electrochemical gradient(GO:0015985) ATP synthesis coupled proton transport(GO:0015986) |
0.0 | 1.6 | GO:0006261 | DNA-dependent DNA replication(GO:0006261) |
0.0 | 0.1 | GO:0042640 | anagen(GO:0042640) |
0.0 | 0.4 | GO:0010762 | regulation of fibroblast migration(GO:0010762) |
0.0 | 0.4 | GO:0033120 | positive regulation of RNA splicing(GO:0033120) |
0.0 | 0.3 | GO:0000381 | regulation of alternative mRNA splicing, via spliceosome(GO:0000381) |
Gene overrepresentation in cellular_component category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
2.4 | 7.2 | GO:0038045 | large latent transforming growth factor-beta complex(GO:0038045) |
1.2 | 3.6 | GO:0005588 | collagen type V trimer(GO:0005588) |
0.6 | 2.5 | GO:0008623 | CHRAC(GO:0008623) |
0.5 | 2.4 | GO:0005587 | collagen type IV trimer(GO:0005587) network-forming collagen trimer(GO:0098642) collagen network(GO:0098645) basement membrane collagen trimer(GO:0098651) |
0.4 | 1.3 | GO:0036387 | nuclear pre-replicative complex(GO:0005656) pre-replicative complex(GO:0036387) |
0.4 | 2.1 | GO:0070820 | tertiary granule(GO:0070820) |
0.4 | 1.2 | GO:0030868 | smooth endoplasmic reticulum membrane(GO:0030868) smooth endoplasmic reticulum part(GO:0097425) |
0.4 | 1.8 | GO:0033063 | Rad51B-Rad51C-Rad51D-XRCC2 complex(GO:0033063) |
0.3 | 1.4 | GO:0090537 | CERF complex(GO:0090537) |
0.3 | 1.8 | GO:0097513 | myosin II filament(GO:0097513) |
0.3 | 1.2 | GO:0061702 | inflammasome complex(GO:0061702) |
0.3 | 0.9 | GO:0034673 | inhibin-betaglycan-ActRII complex(GO:0034673) |
0.3 | 1.0 | GO:0060187 | cell pole(GO:0060187) |
0.2 | 1.4 | GO:0000444 | MIS12/MIND type complex(GO:0000444) |
0.2 | 1.2 | GO:0016035 | zeta DNA polymerase complex(GO:0016035) |
0.2 | 1.0 | GO:0032983 | kainate selective glutamate receptor complex(GO:0032983) |
0.2 | 1.5 | GO:0000015 | phosphopyruvate hydratase complex(GO:0000015) |
0.2 | 1.4 | GO:0042582 | primary lysosome(GO:0005766) azurophil granule(GO:0042582) |
0.1 | 0.7 | GO:0032777 | Piccolo NuA4 histone acetyltransferase complex(GO:0032777) |
0.1 | 1.4 | GO:1990023 | mitotic spindle midzone(GO:1990023) |
0.1 | 0.8 | GO:0070531 | BRCA1-A complex(GO:0070531) |
0.1 | 1.5 | GO:0070419 | nonhomologous end joining complex(GO:0070419) |
0.1 | 1.1 | GO:0097197 | tetraspanin-enriched microdomain(GO:0097197) |
0.1 | 2.4 | GO:0031616 | spindle pole centrosome(GO:0031616) |
0.1 | 5.0 | GO:0032281 | AMPA glutamate receptor complex(GO:0032281) |
0.1 | 1.6 | GO:0042788 | polysomal ribosome(GO:0042788) |
0.1 | 0.3 | GO:0002944 | cyclin K-CDK12 complex(GO:0002944) |
0.1 | 1.1 | GO:0044322 | endoplasmic reticulum quality control compartment(GO:0044322) |
0.1 | 0.4 | GO:1990393 | 3M complex(GO:1990393) |
0.1 | 0.3 | GO:0030289 | protein phosphatase 4 complex(GO:0030289) |
0.1 | 0.4 | GO:0005658 | alpha DNA polymerase:primase complex(GO:0005658) |
0.1 | 0.3 | GO:0005947 | mitochondrial alpha-ketoglutarate dehydrogenase complex(GO:0005947) |
0.1 | 0.5 | GO:0032937 | SREBP-SCAP-Insig complex(GO:0032937) |
0.1 | 0.9 | GO:0031209 | SCAR complex(GO:0031209) |
0.1 | 0.3 | GO:0005968 | Rab-protein geranylgeranyltransferase complex(GO:0005968) |
0.1 | 1.2 | GO:0031527 | filopodium membrane(GO:0031527) |
0.1 | 3.4 | GO:0016459 | myosin complex(GO:0016459) |
0.1 | 1.7 | GO:0031307 | integral component of mitochondrial outer membrane(GO:0031307) |
0.1 | 0.6 | GO:0034364 | high-density lipoprotein particle(GO:0034364) |
0.0 | 1.0 | GO:0016580 | Sin3 complex(GO:0016580) |
0.0 | 1.6 | GO:0060077 | inhibitory synapse(GO:0060077) |
0.0 | 1.2 | GO:0000788 | nuclear nucleosome(GO:0000788) |
0.0 | 1.7 | GO:0016235 | aggresome(GO:0016235) |
0.0 | 0.4 | GO:0097431 | mitotic spindle pole(GO:0097431) |
0.0 | 0.1 | GO:0033185 | dolichol-phosphate-mannose synthase complex(GO:0033185) |
0.0 | 0.6 | GO:0043220 | Schmidt-Lanterman incisure(GO:0043220) |
0.0 | 2.0 | GO:0000791 | euchromatin(GO:0000791) |
0.0 | 0.3 | GO:0030056 | hemidesmosome(GO:0030056) |
0.0 | 0.4 | GO:0042555 | MCM complex(GO:0042555) |
0.0 | 1.5 | GO:0008023 | transcription elongation factor complex(GO:0008023) |
0.0 | 2.3 | GO:0070469 | respiratory chain(GO:0070469) |
0.0 | 0.9 | GO:0035861 | site of double-strand break(GO:0035861) |
0.0 | 0.8 | GO:0030992 | intraciliary transport particle B(GO:0030992) |
0.0 | 0.2 | GO:0032299 | ribonuclease H2 complex(GO:0032299) |
0.0 | 0.4 | GO:0001518 | voltage-gated sodium channel complex(GO:0001518) |
0.0 | 0.3 | GO:0000276 | mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276) |
0.0 | 0.7 | GO:0001917 | photoreceptor inner segment(GO:0001917) |
0.0 | 2.5 | GO:0036064 | ciliary basal body(GO:0036064) |
0.0 | 0.3 | GO:0045120 | pronucleus(GO:0045120) |
0.0 | 0.5 | GO:0031526 | brush border membrane(GO:0031526) |
0.0 | 2.4 | GO:0043296 | apical junction complex(GO:0043296) |
0.0 | 1.0 | GO:0072686 | mitotic spindle(GO:0072686) |
0.0 | 0.1 | GO:0042589 | zymogen granule membrane(GO:0042589) |
0.0 | 0.1 | GO:0046581 | intercellular canaliculus(GO:0046581) |
0.0 | 0.4 | GO:0033270 | paranode region of axon(GO:0033270) |
0.0 | 0.7 | GO:0045171 | intercellular bridge(GO:0045171) |
0.0 | 0.2 | GO:1990635 | proximal dendrite(GO:1990635) |
0.0 | 0.3 | GO:0071782 | endoplasmic reticulum tubular network(GO:0071782) |
0.0 | 1.1 | GO:0016605 | PML body(GO:0016605) |
0.0 | 0.4 | GO:0000786 | nucleosome(GO:0000786) |
0.0 | 0.1 | GO:0000176 | nuclear exosome (RNase complex)(GO:0000176) |
0.0 | 1.1 | GO:0001726 | ruffle(GO:0001726) |
0.0 | 0.3 | GO:0005689 | U12-type spliceosomal complex(GO:0005689) |
0.0 | 3.3 | GO:0045177 | apical part of cell(GO:0045177) |
0.0 | 0.9 | GO:0005604 | basement membrane(GO:0005604) |
0.0 | 1.2 | GO:0031225 | anchored component of membrane(GO:0031225) |
Gene overrepresentation in molecular_function category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
1.8 | 7.2 | GO:0050436 | microfibril binding(GO:0050436) |
0.8 | 2.5 | GO:0005110 | frizzled-2 binding(GO:0005110) |
0.7 | 0.7 | GO:0036361 | racemase and epimerase activity, acting on amino acids and derivatives(GO:0016855) racemase activity, acting on amino acids and derivatives(GO:0036361) amino-acid racemase activity(GO:0047661) |
0.6 | 4.3 | GO:0052650 | NADP-retinol dehydrogenase activity(GO:0052650) |
0.5 | 2.0 | GO:0044729 | hemi-methylated DNA-binding(GO:0044729) |
0.5 | 1.4 | GO:0004517 | nitric-oxide synthase activity(GO:0004517) |
0.4 | 2.5 | GO:0015277 | kainate selective glutamate receptor activity(GO:0015277) |
0.4 | 2.5 | GO:0035727 | lysophosphatidic acid binding(GO:0035727) lysophosphatidic acid receptor activity(GO:0070915) |
0.4 | 1.4 | GO:0001011 | transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087) |
0.3 | 2.0 | GO:0003854 | 3-beta-hydroxy-delta5-steroid dehydrogenase activity(GO:0003854) |
0.3 | 1.3 | GO:0051377 | mannose-ethanolamine phosphotransferase activity(GO:0051377) |
0.3 | 0.9 | GO:0043237 | laminin-1 binding(GO:0043237) |
0.3 | 1.2 | GO:0072320 | volume-sensitive chloride channel activity(GO:0072320) |
0.3 | 1.2 | GO:0004921 | interleukin-11 receptor activity(GO:0004921) interleukin-11 binding(GO:0019970) |
0.3 | 1.1 | GO:0003941 | L-serine ammonia-lyase activity(GO:0003941) |
0.3 | 1.8 | GO:0000150 | recombinase activity(GO:0000150) |
0.2 | 3.5 | GO:0017017 | MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017) |
0.2 | 1.3 | GO:0032453 | histone demethylase activity (H3-K4 specific)(GO:0032453) |
0.2 | 1.2 | GO:0048101 | calmodulin-dependent cyclic-nucleotide phosphodiesterase activity(GO:0004117) calcium- and calmodulin-regulated 3',5'-cyclic-GMP phosphodiesterase activity(GO:0048101) |
0.2 | 1.0 | GO:0015204 | urea transmembrane transporter activity(GO:0015204) |
0.2 | 1.5 | GO:0004634 | phosphopyruvate hydratase activity(GO:0004634) |
0.2 | 3.3 | GO:0005242 | inward rectifier potassium channel activity(GO:0005242) |
0.2 | 1.4 | GO:0032564 | dATP binding(GO:0032564) |
0.2 | 0.5 | GO:0035673 | oligopeptide transmembrane transporter activity(GO:0035673) |
0.1 | 0.6 | GO:0000832 | inositol hexakisphosphate kinase activity(GO:0000828) inositol hexakisphosphate 5-kinase activity(GO:0000832) inositol hexakisphosphate 1-kinase activity(GO:0052723) inositol hexakisphosphate 3-kinase activity(GO:0052724) |
0.1 | 2.0 | GO:0005247 | voltage-gated chloride channel activity(GO:0005247) |
0.1 | 2.2 | GO:0044323 | retinoic acid-responsive element binding(GO:0044323) |
0.1 | 1.3 | GO:0030550 | acetylcholine receptor inhibitor activity(GO:0030550) |
0.1 | 0.7 | GO:0017116 | single-stranded DNA-dependent ATP-dependent DNA helicase activity(GO:0017116) |
0.1 | 3.5 | GO:0043395 | heparan sulfate proteoglycan binding(GO:0043395) |
0.1 | 0.4 | GO:0031752 | D5 dopamine receptor binding(GO:0031752) |
0.1 | 0.7 | GO:0004984 | olfactory receptor activity(GO:0004984) |
0.1 | 0.4 | GO:0008310 | single-stranded DNA 3'-5' exodeoxyribonuclease activity(GO:0008310) |
0.1 | 1.0 | GO:0035033 | histone deacetylase regulator activity(GO:0035033) |
0.1 | 1.8 | GO:0030898 | actin-dependent ATPase activity(GO:0030898) |
0.1 | 0.3 | GO:0001129 | transcription factor activity, RNA polymerase II basal transcription factor binding(GO:0001083) RNA polymerase II transcription factor activity, TBP-class protein binding, involved in preinitiation complex assembly(GO:0001129) RNA polymerase II transcription factor activity, TBP-class protein binding(GO:0001132) |
0.1 | 1.9 | GO:0004181 | metallocarboxypeptidase activity(GO:0004181) |
0.1 | 0.4 | GO:0016230 | sphingomyelin phosphodiesterase activator activity(GO:0016230) |
0.1 | 1.2 | GO:0005024 | transforming growth factor beta-activated receptor activity(GO:0005024) |
0.1 | 3.6 | GO:0005201 | extracellular matrix structural constituent(GO:0005201) |
0.1 | 1.4 | GO:0000014 | single-stranded DNA endodeoxyribonuclease activity(GO:0000014) |
0.1 | 1.1 | GO:0031957 | very long-chain fatty acid-CoA ligase activity(GO:0031957) |
0.1 | 1.1 | GO:0043522 | leucine zipper domain binding(GO:0043522) |
0.1 | 0.8 | GO:0004630 | phospholipase D activity(GO:0004630) |
0.1 | 1.7 | GO:0030215 | semaphorin receptor binding(GO:0030215) |
0.1 | 1.1 | GO:0070513 | death domain binding(GO:0070513) |
0.1 | 1.3 | GO:0043138 | 3'-5' DNA helicase activity(GO:0043138) |
0.1 | 0.6 | GO:0019211 | phosphatase activator activity(GO:0019211) |
0.1 | 0.5 | GO:1901612 | phosphatidylglycerol binding(GO:1901611) cardiolipin binding(GO:1901612) |
0.1 | 0.5 | GO:0070697 | activin receptor binding(GO:0070697) |
0.1 | 1.2 | GO:0017166 | vinculin binding(GO:0017166) |
0.1 | 3.3 | GO:0005547 | phosphatidylinositol-3,4,5-trisphosphate binding(GO:0005547) |
0.1 | 1.9 | GO:0050136 | NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136) |
0.1 | 2.0 | GO:0051183 | vitamin transporter activity(GO:0051183) |
0.1 | 0.9 | GO:0004559 | alpha-mannosidase activity(GO:0004559) |
0.1 | 0.3 | GO:0038132 | neuregulin binding(GO:0038132) |
0.1 | 0.2 | GO:0016174 | NAD(P)H oxidase activity(GO:0016174) |
0.1 | 1.0 | GO:0050811 | GABA-A receptor activity(GO:0004890) GABA receptor binding(GO:0050811) |
0.1 | 2.0 | GO:0017091 | AU-rich element binding(GO:0017091) |
0.1 | 2.1 | GO:0042169 | SH2 domain binding(GO:0042169) |
0.1 | 0.5 | GO:0030159 | receptor signaling complex scaffold activity(GO:0030159) |
0.0 | 1.2 | GO:0008432 | JUN kinase binding(GO:0008432) |
0.0 | 1.3 | GO:0019707 | protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707) |
0.0 | 0.9 | GO:0005528 | macrolide binding(GO:0005527) FK506 binding(GO:0005528) |
0.0 | 0.5 | GO:0015347 | sodium-independent organic anion transmembrane transporter activity(GO:0015347) |
0.0 | 2.4 | GO:0030507 | spectrin binding(GO:0030507) |
0.0 | 1.8 | GO:0005484 | SNAP receptor activity(GO:0005484) |
0.0 | 1.4 | GO:0008198 | ferrous iron binding(GO:0008198) |
0.0 | 0.3 | GO:0005229 | intracellular calcium activated chloride channel activity(GO:0005229) |
0.0 | 0.4 | GO:0031749 | D2 dopamine receptor binding(GO:0031749) |
0.0 | 0.5 | GO:0097157 | pre-mRNA intronic binding(GO:0097157) |
0.0 | 0.5 | GO:0015643 | toxic substance binding(GO:0015643) |
0.0 | 0.2 | GO:0036310 | annealing helicase activity(GO:0036310) |
0.0 | 2.9 | GO:0004004 | RNA helicase activity(GO:0003724) ATP-dependent RNA helicase activity(GO:0004004) |
0.0 | 0.1 | GO:0017150 | tRNA dihydrouridine synthase activity(GO:0017150) |
0.0 | 0.7 | GO:0043422 | protein kinase B binding(GO:0043422) |
0.0 | 0.1 | GO:0004582 | dolichyl-phosphate beta-D-mannosyltransferase activity(GO:0004582) |
0.0 | 0.8 | GO:0070530 | K63-linked polyubiquitin binding(GO:0070530) |
0.0 | 1.0 | GO:0031690 | adrenergic receptor binding(GO:0031690) |
0.0 | 0.1 | GO:0042910 | xenobiotic-transporting ATPase activity(GO:0008559) xenobiotic transporter activity(GO:0042910) |
0.0 | 2.9 | GO:0033613 | activating transcription factor binding(GO:0033613) |
0.0 | 0.5 | GO:0009982 | pseudouridine synthase activity(GO:0009982) |
0.0 | 0.1 | GO:0004534 | 5'-3' exoribonuclease activity(GO:0004534) |
0.0 | 4.8 | GO:0051015 | actin filament binding(GO:0051015) |
0.0 | 0.1 | GO:0034739 | histone deacetylase activity (H4-K16 specific)(GO:0034739) |
0.0 | 0.9 | GO:0050699 | WW domain binding(GO:0050699) |
0.0 | 0.1 | GO:0004694 | eukaryotic translation initiation factor 2alpha kinase activity(GO:0004694) |
0.0 | 1.2 | GO:0031492 | nucleosomal DNA binding(GO:0031492) |
0.0 | 0.2 | GO:0015193 | L-proline transmembrane transporter activity(GO:0015193) |
0.0 | 0.1 | GO:0004441 | inositol-1,4-bisphosphate 1-phosphatase activity(GO:0004441) |
0.0 | 0.1 | GO:0031871 | proteinase activated receptor binding(GO:0031871) |
0.0 | 0.2 | GO:0004523 | RNA-DNA hybrid ribonuclease activity(GO:0004523) |
0.0 | 0.1 | GO:0003910 | DNA ligase activity(GO:0003909) DNA ligase (ATP) activity(GO:0003910) |
0.0 | 0.6 | GO:0000993 | RNA polymerase II core binding(GO:0000993) |
0.0 | 0.2 | GO:0008331 | high voltage-gated calcium channel activity(GO:0008331) |
0.0 | 0.7 | GO:0008175 | tRNA methyltransferase activity(GO:0008175) |
0.0 | 0.4 | GO:0004129 | cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676) |
0.0 | 0.4 | GO:0031435 | mitogen-activated protein kinase kinase kinase binding(GO:0031435) |
0.0 | 0.3 | GO:0031402 | sodium ion binding(GO:0031402) |
0.0 | 0.3 | GO:0008353 | RNA polymerase II carboxy-terminal domain kinase activity(GO:0008353) |
0.0 | 0.1 | GO:0004499 | N,N-dimethylaniline monooxygenase activity(GO:0004499) |
0.0 | 0.1 | GO:0000268 | peroxisome targeting sequence binding(GO:0000268) |
0.0 | 0.4 | GO:0071889 | 14-3-3 protein binding(GO:0071889) |
0.0 | 0.1 | GO:0043125 | ErbB-3 class receptor binding(GO:0043125) |
0.0 | 0.0 | GO:0008192 | RNA guanylyltransferase activity(GO:0008192) |
0.0 | 2.4 | GO:0001078 | transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078) |
0.0 | 1.1 | GO:0016209 | antioxidant activity(GO:0016209) |
0.0 | 0.1 | GO:0036468 | aromatic-L-amino-acid decarboxylase activity(GO:0004058) L-dopa decarboxylase activity(GO:0036468) |
0.0 | 0.4 | GO:0015078 | hydrogen ion transmembrane transporter activity(GO:0015078) |
0.0 | 0.4 | GO:0051059 | NF-kappaB binding(GO:0051059) |
0.0 | 0.4 | GO:0032266 | phosphatidylinositol-3-phosphate binding(GO:0032266) |
0.0 | 1.0 | GO:0004222 | metalloendopeptidase activity(GO:0004222) |
0.0 | 0.2 | GO:0008569 | ATP-dependent microtubule motor activity, minus-end-directed(GO:0008569) |
0.0 | 2.0 | GO:0004721 | phosphoprotein phosphatase activity(GO:0004721) |
0.0 | 1.3 | GO:0017124 | SH3 domain binding(GO:0017124) |
0.0 | 5.0 | GO:0004674 | protein serine/threonine kinase activity(GO:0004674) |
Gene overrepresentation in C2:CP category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.3 | 0.3 | PID_INTEGRIN4_PATHWAY | Alpha6 beta4 integrin-ligand interactions |
0.1 | 2.5 | PID_LPA4_PATHWAY | LPA4-mediated signaling events |
0.1 | 6.0 | NABA_COLLAGENS | Genes encoding collagen proteins |
0.1 | 3.6 | PID_ARF6_PATHWAY | Arf6 signaling events |
0.1 | 2.5 | PID_WNT_SIGNALING_PATHWAY | Wnt signaling network |
0.1 | 1.7 | PID_INSULIN_GLUCOSE_PATHWAY | Insulin-mediated glucose transport |
0.1 | 3.2 | PID_ATM_PATHWAY | ATM pathway |
0.1 | 2.2 | PID_AURORA_A_PATHWAY | Aurora A signaling |
0.1 | 2.8 | PID_TAP63_PATHWAY | Validated transcriptional targets of TAp63 isoforms |
0.1 | 1.8 | PID_A6B1_A6B4_INTEGRIN_PATHWAY | a6b1 and a6b4 Integrin signaling |
0.1 | 1.5 | PID_HDAC_CLASSIII_PATHWAY | Signaling events mediated by HDAC Class III |
0.0 | 2.4 | PID_NETRIN_PATHWAY | Netrin-mediated signaling events |
0.0 | 0.9 | NABA_BASEMENT_MEMBRANES | Genes encoding structural components of basement membranes |
0.0 | 0.4 | PID_S1P_S1P4_PATHWAY | S1P4 pathway |
0.0 | 1.5 | PID_NCADHERIN_PATHWAY | N-cadherin signaling events |
0.0 | 0.8 | PID_UPA_UPAR_PATHWAY | Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling |
0.0 | 0.3 | PID_RHODOPSIN_PATHWAY | Visual signal transduction: Rods |
0.0 | 0.5 | PID_HEDGEHOG_2PATHWAY | Signaling events mediated by the Hedgehog family |
0.0 | 0.9 | PID_ECADHERIN_NASCENT_AJ_PATHWAY | E-cadherin signaling in the nascent adherens junction |
0.0 | 1.1 | PID_BMP_PATHWAY | BMP receptor signaling |
0.0 | 1.0 | PID_ERBB4_PATHWAY | ErbB4 signaling events |
0.0 | 0.4 | PID_SYNDECAN_4_PATHWAY | Syndecan-4-mediated signaling events |
0.0 | 0.4 | PID_ALK1_PATHWAY | ALK1 signaling events |
0.0 | 1.7 | NABA_ECM_AFFILIATED | Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins |
0.0 | 1.5 | NABA_ECM_GLYCOPROTEINS | Genes encoding structural ECM glycoproteins |
0.0 | 1.0 | PID_AR_PATHWAY | Coregulation of Androgen receptor activity |
0.0 | 0.1 | PID_DNA_PK_PATHWAY | DNA-PK pathway in nonhomologous end joining |
0.0 | 0.1 | SA_PTEN_PATHWAY | PTEN is a tumor suppressor that dephosphorylates the lipid messenger phosphatidylinositol triphosphate. |
Gene overrepresentation in C2:CP:REACTOME category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.2 | 2.0 | REACTOME_SYNTHESIS_OF_BILE_ACIDS_AND_BILE_SALTS_VIA_24_HYDROXYCHOLESTEROL | Genes involved in Synthesis of bile acids and bile salts via 24-hydroxycholesterol |
0.2 | 2.2 | REACTOME_P2Y_RECEPTORS | Genes involved in P2Y receptors |
0.1 | 1.8 | REACTOME_PROTEOLYTIC_CLEAVAGE_OF_SNARE_COMPLEX_PROTEINS | Genes involved in Proteolytic cleavage of SNARE complex proteins |
0.1 | 6.2 | REACTOME_NCAM1_INTERACTIONS | Genes involved in NCAM1 interactions |
0.1 | 3.0 | REACTOME_SYNTHESIS_OF_GLYCOSYLPHOSPHATIDYLINOSITOL_GPI | Genes involved in Synthesis of glycosylphosphatidylinositol (GPI) |
0.1 | 1.1 | REACTOME_G2_M_DNA_DAMAGE_CHECKPOINT | Genes involved in G2/M DNA damage checkpoint |
0.1 | 1.4 | REACTOME_APOPTOSIS_INDUCED_DNA_FRAGMENTATION | Genes involved in Apoptosis induced DNA fragmentation |
0.1 | 1.2 | REACTOME_INFLAMMASOMES | Genes involved in Inflammasomes |
0.1 | 1.3 | REACTOME_UNWINDING_OF_DNA | Genes involved in Unwinding of DNA |
0.1 | 1.7 | REACTOME_METABOLISM_OF_PORPHYRINS | Genes involved in Metabolism of porphyrins |
0.1 | 3.3 | REACTOME_VOLTAGE_GATED_POTASSIUM_CHANNELS | Genes involved in Voltage gated Potassium channels |
0.1 | 1.1 | REACTOME_DEGRADATION_OF_THE_EXTRACELLULAR_MATRIX | Genes involved in Degradation of the extracellular matrix |
0.1 | 1.5 | REACTOME_TRAFFICKING_OF_GLUR2_CONTAINING_AMPA_RECEPTORS | Genes involved in Trafficking of GluR2-containing AMPA receptors |
0.1 | 0.3 | REACTOME_OLFACTORY_SIGNALING_PATHWAY | Genes involved in Olfactory Signaling Pathway |
0.1 | 1.7 | REACTOME_ENOS_ACTIVATION_AND_REGULATION | Genes involved in eNOS activation and regulation |
0.1 | 1.0 | REACTOME_IONOTROPIC_ACTIVITY_OF_KAINATE_RECEPTORS | Genes involved in Ionotropic activity of Kainate Receptors |
0.1 | 1.8 | REACTOME_SEMA4D_INDUCED_CELL_MIGRATION_AND_GROWTH_CONE_COLLAPSE | Genes involved in Sema4D induced cell migration and growth-cone collapse |
0.1 | 2.0 | REACTOME_MYOGENESIS | Genes involved in Myogenesis |
0.1 | 0.4 | REACTOME_THROMBIN_SIGNALLING_THROUGH_PROTEINASE_ACTIVATED_RECEPTORS_PARS | Genes involved in Thrombin signalling through proteinase activated receptors (PARs) |
0.1 | 1.4 | REACTOME_LATENT_INFECTION_OF_HOMO_SAPIENS_WITH_MYCOBACTERIUM_TUBERCULOSIS | Genes involved in Latent infection of Homo sapiens with Mycobacterium tuberculosis |
0.1 | 1.0 | REACTOME_AMINE_COMPOUND_SLC_TRANSPORTERS | Genes involved in Amine compound SLC transporters |
0.0 | 1.2 | REACTOME_STRIATED_MUSCLE_CONTRACTION | Genes involved in Striated Muscle Contraction |
0.0 | 0.9 | REACTOME_ACTIVATION_OF_BH3_ONLY_PROTEINS | Genes involved in Activation of BH3-only proteins |
0.0 | 0.6 | REACTOME_PURINE_RIBONUCLEOSIDE_MONOPHOSPHATE_BIOSYNTHESIS | Genes involved in Purine ribonucleoside monophosphate biosynthesis |
0.0 | 1.1 | REACTOME_SIGNALING_BY_BMP | Genes involved in Signaling by BMP |
0.0 | 1.0 | REACTOME_CIRCADIAN_REPRESSION_OF_EXPRESSION_BY_REV_ERBA | Genes involved in Circadian Repression of Expression by REV-ERBA |
0.0 | 0.8 | REACTOME_SYNTHESIS_AND_INTERCONVERSION_OF_NUCLEOTIDE_DI_AND_TRIPHOSPHATES | Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates |
0.0 | 0.5 | REACTOME_DESTABILIZATION_OF_MRNA_BY_TRISTETRAPROLIN_TTP | Genes involved in Destabilization of mRNA by Tristetraprolin (TTP) |
0.0 | 1.0 | REACTOME_GLYCOLYSIS | Genes involved in Glycolysis |
0.0 | 0.5 | REACTOME_BRANCHED_CHAIN_AMINO_ACID_CATABOLISM | Genes involved in Branched-chain amino acid catabolism |
0.0 | 0.2 | REACTOME_TRYPTOPHAN_CATABOLISM | Genes involved in Tryptophan catabolism |
0.0 | 0.4 | REACTOME_TGF_BETA_RECEPTOR_SIGNALING_IN_EMT_EPITHELIAL_TO_MESENCHYMAL_TRANSITION | Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition) |
0.0 | 0.3 | REACTOME_RNA_POL_II_TRANSCRIPTION_PRE_INITIATION_AND_PROMOTER_OPENING | Genes involved in RNA Polymerase II Transcription Pre-Initiation And Promoter Opening |
0.0 | 0.1 | REACTOME_CYTOSOLIC_SULFONATION_OF_SMALL_MOLECULES | Genes involved in Cytosolic sulfonation of small molecules |
0.0 | 0.0 | REACTOME_MRNA_CAPPING | Genes involved in mRNA Capping |
0.0 | 1.3 | REACTOME_DNA_REPAIR | Genes involved in DNA Repair |