Motif ID: Hoxa2

Z-value: 1.062


Transcription factors associated with Hoxa2:

Gene SymbolEntrez IDGene Name
Hoxa2 ENSMUSG00000014704.8 Hoxa2



Activity profile for motif Hoxa2.

activity profile for motif Hoxa2


Sorted Z-values histogram for motif Hoxa2

Sorted Z-values for motif Hoxa2



Network of associatons between targets according to the STRING database.



First level regulatory network of Hoxa2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr5_+_139543889 12.728 ENSMUST00000174792.1
ENSMUST00000031523.8
Uncx

UNC homeobox

chr8_-_4779513 11.617 ENSMUST00000022945.7
Shcbp1
Shc SH2-domain binding protein 1
chr1_-_119053339 8.004 ENSMUST00000161301.1
ENSMUST00000161451.1
ENSMUST00000162607.1
Gli2


GLI-Kruppel family member GLI2


chr2_-_117342949 7.772 ENSMUST00000102534.4
Rasgrp1
RAS guanyl releasing protein 1
chr2_-_84775420 7.425 ENSMUST00000111641.1
Serping1
serine (or cysteine) peptidase inhibitor, clade G, member 1
chr2_-_117342709 7.345 ENSMUST00000173541.1
ENSMUST00000172901.1
ENSMUST00000173252.1
Rasgrp1


RAS guanyl releasing protein 1


chr2_-_117342831 7.265 ENSMUST00000178884.1
Rasgrp1
RAS guanyl releasing protein 1
chr1_-_119053619 7.038 ENSMUST00000062483.8
Gli2
GLI-Kruppel family member GLI2
chr2_-_84775388 6.950 ENSMUST00000023994.3
Serping1
serine (or cysteine) peptidase inhibitor, clade G, member 1
chr2_-_69206133 6.420 ENSMUST00000112320.1
Spc25
SPC25, NDC80 kinetochore complex component, homolog (S. cerevisiae)
chr2_-_69206146 5.810 ENSMUST00000127243.1
ENSMUST00000149643.1
ENSMUST00000167875.2
ENSMUST00000005365.8
Spc25



SPC25, NDC80 kinetochore complex component, homolog (S. cerevisiae)



chr14_-_34374617 5.639 ENSMUST00000023826.4
Sncg
synuclein, gamma
chr15_-_78773452 5.199 ENSMUST00000018313.5
Mfng
MFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase
chr8_-_110902442 4.667 ENSMUST00000041382.6
Fuk
fucokinase
chr5_+_115908644 4.100 ENSMUST00000141101.1
Cit
citron
chr9_-_21760275 4.017 ENSMUST00000098942.4
Spc24
SPC24, NDC80 kinetochore complex component, homolog (S. cerevisiae)
chr3_+_55782500 3.853 ENSMUST00000075422.4
Mab21l1
mab-21-like 1 (C. elegans)
chr9_-_106158109 3.821 ENSMUST00000159809.1
ENSMUST00000162562.1
ENSMUST00000036382.6
ENSMUST00000112543.2
Glyctk



glycerate kinase



chr11_-_100356116 3.778 ENSMUST00000138603.2
Hap1
huntingtin-associated protein 1
chr11_-_100356078 3.682 ENSMUST00000103124.4
Hap1
huntingtin-associated protein 1
chr5_+_92683625 3.592 ENSMUST00000168878.1
Shroom3
shroom family member 3
chr2_+_181763315 3.526 ENSMUST00000081125.4
Myt1
myelin transcription factor 1
chr6_+_14901344 3.493 ENSMUST00000115477.1
Foxp2
forkhead box P2
chr14_+_65806066 3.490 ENSMUST00000139644.1
Pbk
PDZ binding kinase
chr8_-_105471481 3.444 ENSMUST00000014990.6
Tppp3
tubulin polymerization-promoting protein family member 3
chr9_-_73968901 3.309 ENSMUST00000184666.1
Unc13c
unc-13 homolog C (C. elegans)
chr1_-_9700209 3.308 ENSMUST00000088658.4
Mybl1
myeloblastosis oncogene-like 1
chr9_+_122951051 3.215 ENSMUST00000040717.5
Kif15
kinesin family member 15
chr10_-_92162753 3.206 ENSMUST00000182197.1
Rmst
rhabdomyosarcoma 2 associated transcript (non-coding RNA)
chr7_+_27473761 3.188 ENSMUST00000068641.6
Sertad3
SERTA domain containing 3
chr1_-_133907053 3.120 ENSMUST00000149380.1
ENSMUST00000124051.2
Optc

opticin

chr4_+_134510999 3.117 ENSMUST00000105866.2
Aunip
aurora kinase A and ninein interacting protein
chr8_-_87959560 3.075 ENSMUST00000109655.2
Zfp423
zinc finger protein 423
chr9_+_58134017 2.853 ENSMUST00000134955.1
ENSMUST00000147134.1
ENSMUST00000170397.1
Stra6


stimulated by retinoic acid gene 6


chr11_-_58801944 2.798 ENSMUST00000094156.4
ENSMUST00000060581.3
Fam183b

family with sequence similarity 183, member B

chr4_-_110290884 2.783 ENSMUST00000142722.1
Elavl4
ELAV (embryonic lethal, abnormal vision, Drosophila)-like 4 (Hu antigen D)
chr17_+_78491549 2.691 ENSMUST00000079363.4
Gm10093
predicted pseudogene 10093
chr1_-_133906973 2.633 ENSMUST00000126123.1
Optc
opticin
chr10_-_128804353 2.467 ENSMUST00000051011.7
Tmem198b
transmembrane protein 198b
chr6_+_34709442 2.430 ENSMUST00000115021.1
Cald1
caldesmon 1
chr2_+_156840966 2.408 ENSMUST00000109564.1
Tgif2
TGFB-induced factor homeobox 2
chr11_-_106998483 2.367 ENSMUST00000124541.1
Kpna2
karyopherin (importin) alpha 2
chr7_+_45163915 2.361 ENSMUST00000085374.5
Slc17a7
solute carrier family 17 (sodium-dependent inorganic phosphate cotransporter), member 7
chr2_+_102706356 2.342 ENSMUST00000123759.1
ENSMUST00000111212.1
ENSMUST00000005220.4
Slc1a2


solute carrier family 1 (glial high affinity glutamate transporter), member 2


chr2_+_124089961 2.311 ENSMUST00000103241.1
Sema6d
sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6D
chr9_+_15520830 2.308 ENSMUST00000178999.1
Smco4
single-pass membrane protein with coiled-coil domains 4
chr4_-_35157404 2.301 ENSMUST00000102975.3
Mob3b
MOB kinase activator 3B
chr19_+_23723279 2.223 ENSMUST00000067077.1
Gm9938
predicted gene 9938
chr12_+_44328882 2.222 ENSMUST00000020939.8
ENSMUST00000110748.2
Nrcam

neuron-glia-CAM-related cell adhesion molecule

chr6_+_34709610 2.213 ENSMUST00000031775.6
Cald1
caldesmon 1
chr9_+_58129062 2.155 ENSMUST00000085677.2
Stra6
stimulated by retinoic acid gene 6
chr10_-_26078987 2.147 ENSMUST00000066049.6
Tmem200a
transmembrane protein 200A
chr4_-_155010984 2.141 ENSMUST00000105631.2
ENSMUST00000139976.2
ENSMUST00000145662.2
Plch2


phospholipase C, eta 2


chr3_-_107931817 2.120 ENSMUST00000004137.4
Gstm7
glutathione S-transferase, mu 7
chr4_-_83285141 2.089 ENSMUST00000150522.1
Ttc39b
tetratricopeptide repeat domain 39B
chr19_-_10203880 2.078 ENSMUST00000142241.1
ENSMUST00000116542.2
ENSMUST00000025651.5
ENSMUST00000156291.1
Fen1



flap structure specific endonuclease 1



chr17_-_53539411 2.070 ENSMUST00000056198.3
Pp2d1
protein phosphatase 2C-like domain containing 1
chr9_+_58134535 2.006 ENSMUST00000128378.1
ENSMUST00000150820.1
ENSMUST00000167479.1
ENSMUST00000134450.1
Stra6



stimulated by retinoic acid gene 6



chr10_-_81349085 1.999 ENSMUST00000141171.1
Hmg20b
high mobility group 20B
chr7_+_100537192 1.997 ENSMUST00000120454.1
Coa4
cytochrome c oxidase assembly factor 4
chr17_+_66123520 1.977 ENSMUST00000163605.2
Ddx11
DEAD/H (Asp-Glu-Ala-Asp/His) box helicase 11
chr9_+_58129321 1.972 ENSMUST00000034880.3
Stra6
stimulated by retinoic acid gene 6
chr4_+_116596672 1.965 ENSMUST00000051869.7
Ccdc17
coiled-coil domain containing 17
chrX_-_102157065 1.934 ENSMUST00000056904.2
Ercc6l
excision repair cross-complementing rodent repair deficiency complementation group 6 like
chr15_-_84447037 1.904 ENSMUST00000080751.2
1810041L15Rik
RIKEN cDNA 1810041L15 gene
chr15_+_31224371 1.900 ENSMUST00000044524.9
Dap
death-associated protein
chr7_-_132786914 1.876 ENSMUST00000065371.7
ENSMUST00000106166.1
Fam53b

family with sequence similarity 53, member B

chr4_+_46450892 1.848 ENSMUST00000102926.4
Anp32b
acidic (leucine-rich) nuclear phosphoprotein 32 family, member B
chr3_+_32708546 1.799 ENSMUST00000029214.7
Actl6a
actin-like 6A
chr3_+_124321031 1.779 ENSMUST00000058994.4
Tram1l1
translocation associated membrane protein 1-like 1
chr3_-_157925056 1.753 ENSMUST00000118539.1
Cth
cystathionase (cystathionine gamma-lyase)
chr7_+_142460834 1.741 ENSMUST00000018963.4
ENSMUST00000105967.1
Lsp1

lymphocyte specific 1

chr19_-_41743665 1.714 ENSMUST00000025993.3
Slit1
slit homolog 1 (Drosophila)
chr11_+_94327984 1.714 ENSMUST00000107818.2
ENSMUST00000051221.6
Ankrd40

ankyrin repeat domain 40

chrX_-_142306170 1.711 ENSMUST00000134825.2
Kcne1l
potassium voltage-gated channel, Isk-related family, member 1-like, pseudogene
chr9_+_3404058 1.693 ENSMUST00000027027.5
Cwf19l2
CWF19-like 2, cell cycle control (S. pombe)
chr17_+_24426676 1.692 ENSMUST00000024946.5
Eci1
enoyl-Coenzyme A delta isomerase 1
chr5_-_130024280 1.690 ENSMUST00000161640.1
ENSMUST00000161884.1
ENSMUST00000161094.1
Asl


argininosuccinate lyase


chr15_+_59648350 1.675 ENSMUST00000067543.6
Trib1
tribbles homolog 1 (Drosophila)
chr5_-_24527276 1.668 ENSMUST00000088311.4
Gbx1
gastrulation brain homeobox 1
chr13_+_117220584 1.657 ENSMUST00000022242.7
Emb
embigin
chrX_+_96455359 1.638 ENSMUST00000033553.7
Heph
hephaestin
chr1_+_187215501 1.624 ENSMUST00000097443.3
ENSMUST00000065573.7
ENSMUST00000110943.2
ENSMUST00000044812.5
Gpatch2



G patch domain containing 2



chr9_-_62510498 1.603 ENSMUST00000164246.2
Coro2b
coronin, actin binding protein, 2B
chrX_+_73192222 1.589 ENSMUST00000101486.4
Xlr3b
X-linked lymphocyte-regulated 3B
chr3_+_76075583 1.582 ENSMUST00000160261.1
Fstl5
follistatin-like 5
chr13_-_54565368 1.561 ENSMUST00000026989.8
4833439L19Rik
RIKEN cDNA 4833439L19 gene
chr17_-_6782775 1.524 ENSMUST00000064234.6
Ezr
ezrin
chr13_-_54565299 1.505 ENSMUST00000153065.1
ENSMUST00000126295.1
ENSMUST00000143144.1
ENSMUST00000132136.1
4833439L19Rik



RIKEN cDNA 4833439L19 gene



chr4_+_15881255 1.504 ENSMUST00000029876.1
Calb1
calbindin 1
chr9_+_51621425 1.453 ENSMUST00000089534.4
Gm7293
predicted gene 7293
chr17_-_25880236 1.420 ENSMUST00000176696.1
ENSMUST00000095487.5
Wfikkn1

WAP, FS, Ig, KU, and NTR-containing protein 1

chr15_+_99717515 1.408 ENSMUST00000023760.6
ENSMUST00000162194.1
Gpd1

glycerol-3-phosphate dehydrogenase 1 (soluble)

chr1_-_175688353 1.391 ENSMUST00000104984.1
Chml
choroideremia-like
chr2_+_174285352 1.385 ENSMUST00000130761.1
Gnas
GNAS (guanine nucleotide binding protein, alpha stimulating) complex locus
chr7_+_100495987 1.376 ENSMUST00000133044.1
Ucp2
uncoupling protein 2 (mitochondrial, proton carrier)
chr11_-_68927049 1.360 ENSMUST00000038932.7
Odf4
outer dense fiber of sperm tails 4
chr18_-_6136057 1.339 ENSMUST00000182559.1
Arhgap12
Rho GTPase activating protein 12
chr1_+_143739551 1.307 ENSMUST00000050491.9
Glrx2
glutaredoxin 2 (thioltransferase)
chr17_-_45474839 1.290 ENSMUST00000024731.8
Spats1
spermatogenesis associated, serine-rich 1
chr7_-_79935258 1.253 ENSMUST00000048731.5
2610034B18Rik
RIKEN cDNA 2610034B18 gene
chr6_+_5390387 1.252 ENSMUST00000183358.1
Asb4
ankyrin repeat and SOCS box-containing 4
chr9_+_58129476 1.217 ENSMUST00000133287.1
Stra6
stimulated by retinoic acid gene 6
chr9_-_72111172 1.216 ENSMUST00000183992.1
Tcf12
transcription factor 12
chr4_-_108118528 1.174 ENSMUST00000030340.8
Scp2
sterol carrier protein 2, liver
chr3_+_85915722 1.168 ENSMUST00000054148.7
Gm9790
predicted gene 9790
chr12_-_87233556 1.156 ENSMUST00000021423.7
Noxred1
NADP+ dependent oxidoreductase domain containing 1
chr8_+_83389846 1.144 ENSMUST00000002259.6
Clgn
calmegin
chr13_+_23575753 1.142 ENSMUST00000105105.1
Hist1h3d
histone cluster 1, H3d
chr10_-_63421739 1.105 ENSMUST00000054760.4
Gm7075
predicted gene 7075
chr3_-_58525867 1.101 ENSMUST00000029385.7
Serp1
stress-associated endoplasmic reticulum protein 1
chr7_-_133122615 1.095 ENSMUST00000167218.1
Ctbp2
C-terminal binding protein 2
chr19_+_24875679 1.087 ENSMUST00000073080.5
Gm10053
predicted gene 10053
chr4_-_92191749 1.087 ENSMUST00000123179.1
Gm12666
predicted gene 12666
chr5_+_115235836 1.081 ENSMUST00000081497.6
Pop5
processing of precursor 5, ribonuclease P/MRP family (S. cerevisiae)
chr4_-_43653542 1.081 ENSMUST00000084646.4
Spag8
sperm associated antigen 8
chr8_-_94696223 1.066 ENSMUST00000034227.4
Pllp
plasma membrane proteolipid
chr14_-_54409469 1.055 ENSMUST00000000984.4
Slc7a7
solute carrier family 7 (cationic amino acid transporter, y+ system), member 7
chr3_-_92429403 1.052 ENSMUST00000047300.7
Gm9774
predicted pseudogene 9774
chr10_-_95673451 1.043 ENSMUST00000099328.1
Anapc15-ps
anaphase prompoting complex C subunit 15, pseudogene
chrX_-_103483205 1.041 ENSMUST00000127786.2
Xist
inactive X specific transcripts
chr11_+_108682602 1.036 ENSMUST00000106718.3
ENSMUST00000106715.1
ENSMUST00000106724.3
Cep112


centrosomal protein 112


chrM_+_7759 1.034 ENSMUST00000082407.1
ENSMUST00000082408.1
mt-Atp8
mt-Atp6
mitochondrially encoded ATP synthase 8
mitochondrially encoded ATP synthase 6
chr1_+_143739573 1.010 ENSMUST00000111957.3
ENSMUST00000145571.1
Glrx2

glutaredoxin 2 (thioltransferase)

chr2_+_103957976 1.007 ENSMUST00000156813.1
ENSMUST00000170926.1
Lmo2

LIM domain only 2

chrX_-_17571563 1.007 ENSMUST00000177213.1
Fundc1
FUN14 domain containing 1
chr6_+_11925869 1.006 ENSMUST00000115510.1
ENSMUST00000115511.2
ENSMUST00000090632.4
Phf14


PHD finger protein 14


chr12_+_109747903 1.005 ENSMUST00000183084.1
ENSMUST00000182300.1
Mirg

miRNA containing gene

chr7_-_27985796 0.996 ENSMUST00000099111.3
Zfp850
zinc finger protein 850
chr3_+_88716838 0.996 ENSMUST00000029692.8
ENSMUST00000171645.1
Rit1

Ras-like without CAAX 1

chr7_-_145283915 0.988 ENSMUST00000058022.4
Tpcn2
two pore segment channel 2
chr18_+_76930017 0.981 ENSMUST00000026487.4
Ier3ip1
immediate early response 3 interacting protein 1
chr7_+_81858993 0.972 ENSMUST00000041890.1
Tm6sf1
transmembrane 6 superfamily member 1
chr6_+_83156401 0.972 ENSMUST00000032106.4
1700003E16Rik
RIKEN cDNA 1700003E16 gene
chr9_+_80066939 0.970 ENSMUST00000164859.1
Senp6
SUMO/sentrin specific peptidase 6
chr12_+_9029982 0.960 ENSMUST00000085741.1
Ttc32
tetratricopeptide repeat domain 32
chr9_+_122923050 0.957 ENSMUST00000051667.7
ENSMUST00000148851.1
Zfp105

zinc finger protein 105

chr17_+_80290206 0.954 ENSMUST00000061703.9
Morn2
MORN repeat containing 2
chrX_+_73214333 0.941 ENSMUST00000156188.1
ENSMUST00000069077.3
ENSMUST00000069103.4
ENSMUST00000114506.1
ENSMUST00000081827.3
Xlr4b




X-linked lymphocyte-regulated 4B




chr17_-_6655939 0.938 ENSMUST00000179554.1
Dynlt1f
dynein light chain Tctex-type 1F
chr2_-_165388245 0.930 ENSMUST00000103084.3
Zfp334
zinc finger protein 334
chr2_+_174285256 0.925 ENSMUST00000130940.1
Gnas
GNAS (guanine nucleotide binding protein, alpha stimulating) complex locus
chr6_-_21851914 0.925 ENSMUST00000134635.1
ENSMUST00000123116.1
ENSMUST00000120965.1
Tspan12


tetraspanin 12


chr18_-_24020307 0.923 ENSMUST00000153337.1
ENSMUST00000148525.1
Zfp191

zinc finger protein 191

chr2_+_5951440 0.921 ENSMUST00000060092.6
Upf2
UPF2 regulator of nonsense transcripts homolog (yeast)
chr3_-_39359128 0.909 ENSMUST00000056409.2
Gm9845
predicted pseudogene 9845
chr16_-_45693658 0.901 ENSMUST00000114562.2
ENSMUST00000036617.7
Tmprss7

transmembrane serine protease 7

chr3_+_88716884 0.900 ENSMUST00000172252.1
Rit1
Ras-like without CAAX 1
chr17_-_71002488 0.874 ENSMUST00000148960.1
Myl12a
myosin, light chain 12A, regulatory, non-sarcomeric
chr10_+_57486354 0.872 ENSMUST00000079833.4
Hsf2
heat shock factor 2
chr14_-_13961202 0.869 ENSMUST00000065865.8
Thoc7
THO complex 7 homolog (Drosophila)
chr2_-_60963192 0.867 ENSMUST00000028347.6
Rbms1
RNA binding motif, single stranded interacting protein 1
chrX_+_37126777 0.857 ENSMUST00000016553.4
Nkap
NFKB activating protein
chrX_-_73265390 0.855 ENSMUST00000080839.1
Xlr3c
X-linked lymphocyte-regulated 3C
chr18_-_56562261 0.852 ENSMUST00000066208.6
ENSMUST00000172734.1
Aldh7a1

aldehyde dehydrogenase family 7, member A1

chr7_-_3720382 0.841 ENSMUST00000078451.6
Pirb
paired Ig-like receptor B
chr15_-_81729864 0.840 ENSMUST00000171115.1
ENSMUST00000170134.1
ENSMUST00000052374.5
Rangap1


RAN GTPase activating protein 1


chr16_+_44347121 0.827 ENSMUST00000050897.6
Spice1
spindle and centriole associated protein 1
chr11_+_21239279 0.827 ENSMUST00000006221.7
ENSMUST00000109578.1
Vps54

vacuolar protein sorting 54 (yeast)

chr9_-_44344159 0.814 ENSMUST00000077353.7
Hmbs
hydroxymethylbilane synthase
chr2_+_31572701 0.814 ENSMUST00000055244.6
Fubp3
far upstream element (FUSE) binding protein 3
chr4_+_98395768 0.814 ENSMUST00000041284.3
Inadl
InaD-like (Drosophila)
chr19_-_6969746 0.810 ENSMUST00000025912.8
Plcb3
phospholipase C, beta 3
chr16_+_38346986 0.807 ENSMUST00000050273.8
ENSMUST00000120495.1
ENSMUST00000119704.1
Cox17

Gm21987
cytochrome c oxidase assembly protein 17

predicted gene 21987
chr17_-_6317474 0.806 ENSMUST00000169415.1
Dynlt1a
dynein light chain Tctex-type 1A
chr2_+_31572775 0.802 ENSMUST00000137889.1
Fubp3
far upstream element (FUSE) binding protein 3
chr12_+_76324860 0.796 ENSMUST00000095610.2
ENSMUST00000154078.2
Akap5

A kinase (PRKA) anchor protein 5

chr9_-_71485893 0.785 ENSMUST00000034720.5
Polr2m
polymerase (RNA) II (DNA directed) polypeptide M
chrX_-_36874111 0.773 ENSMUST00000047486.5
C330007P06Rik
RIKEN cDNA C330007P06 gene
chr12_-_15816762 0.773 ENSMUST00000020922.7
Trib2
tribbles homolog 2 (Drosophila)
chr18_-_10610124 0.761 ENSMUST00000097670.3
Esco1
establishment of cohesion 1 homolog 1 (S. cerevisiae)
chr3_+_134828993 0.756 ENSMUST00000029822.4
Tacr3
tachykinin receptor 3
chr4_-_94603239 0.754 ENSMUST00000107107.2
Plaa
phospholipase A2, activating protein
chr12_-_16800886 0.754 ENSMUST00000161998.1
Greb1
gene regulated by estrogen in breast cancer protein
chr6_+_14901440 0.751 ENSMUST00000128567.1
Foxp2
forkhead box P2
chr18_-_56562215 0.748 ENSMUST00000170309.1
Aldh7a1
aldehyde dehydrogenase family 7, member A1
chr14_+_53665912 0.741 ENSMUST00000181768.1
Trav3-3
T cell receptor alpha variable 3-3
chr3_+_103279293 0.741 ENSMUST00000029444.6
ENSMUST00000106860.1
Trim33

tripartite motif-containing 33

chr8_+_83389878 0.740 ENSMUST00000109831.2
Clgn
calmegin
chr15_-_55548164 0.732 ENSMUST00000165356.1
Mrpl13
mitochondrial ribosomal protein L13
chr1_+_134560157 0.732 ENSMUST00000047714.7
Kdm5b
lysine (K)-specific demethylase 5B
chr8_-_83332416 0.730 ENSMUST00000177594.1
ENSMUST00000053902.3
Elmod2

ELMO/CED-12 domain containing 2

chr5_+_106609098 0.728 ENSMUST00000167618.1
Gm17304
predicted gene, 17304
chr2_-_73453918 0.725 ENSMUST00000102679.1
Wipf1
WAS/WASL interacting protein family, member 1
chr1_+_83159733 0.708 ENSMUST00000113436.1
ENSMUST00000065436.3
ENSMUST00000065403.6
Daw1


dynein assembly factor with WDR repeat domains 1


chr17_-_32166879 0.701 ENSMUST00000087723.3
Notch3
notch 3
chr1_-_170215380 0.698 ENSMUST00000027979.7
ENSMUST00000123399.1
Uhmk1

U2AF homology motif (UHM) kinase 1

chr17_+_46496753 0.698 ENSMUST00000046497.6
Dnph1
2'-deoxynucleoside 5'-phosphate N-hydrolase 1
chr19_-_30549516 0.689 ENSMUST00000025803.8
Dkk1
dickkopf homolog 1 (Xenopus laevis)
chr1_-_180813534 0.684 ENSMUST00000159789.1
ENSMUST00000081026.4
H3f3a

H3 histone, family 3A

chr2_-_149798701 0.681 ENSMUST00000148202.1
ENSMUST00000139471.1
Gm14133

predicted gene 14133

chrX_-_17572241 0.680 ENSMUST00000176638.1
ENSMUST00000026016.6
Fundc1

FUN14 domain containing 1

chr1_-_79671966 0.671 ENSMUST00000162342.1
Ap1s3
adaptor-related protein complex AP-1, sigma 3
chr3_-_10351313 0.669 ENSMUST00000108377.1
ENSMUST00000037839.5
Zfand1

zinc finger, AN1-type domain 1

chr4_-_43653560 0.668 ENSMUST00000107870.2
Spag8
sperm associated antigen 8
chr9_+_73044833 0.664 ENSMUST00000184146.1
ENSMUST00000034722.4
Rab27a

RAB27A, member RAS oncogene family

chr4_+_145510759 0.636 ENSMUST00000105742.1
ENSMUST00000136309.1
Gm13225

predicted gene 13225

chr18_-_10610048 0.635 ENSMUST00000115864.1
Esco1
establishment of cohesion 1 homolog 1 (S. cerevisiae)
chr7_-_28050028 0.628 ENSMUST00000032824.9
Psmc4
proteasome (prosome, macropain) 26S subunit, ATPase, 4
chr5_-_130003000 0.625 ENSMUST00000026613.7
Gusb
glucuronidase, beta

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
4.8 14.4 GO:0001869 regulation of complement activation, lectin pathway(GO:0001868) negative regulation of complement activation, lectin pathway(GO:0001869)
3.8 15.0 GO:0060032 notochord regression(GO:0060032)
2.5 22.4 GO:1902715 positive regulation of interferon-gamma secretion(GO:1902715)
2.0 10.2 GO:0046864 retinol transport(GO:0034633) isoprenoid transport(GO:0046864) terpenoid transport(GO:0046865) alveolar primary septum development(GO:0061143)
1.8 12.7 GO:0035726 common myeloid progenitor cell proliferation(GO:0035726)
1.5 7.5 GO:0032901 positive regulation of neurotrophin production(GO:0032901)
1.2 4.7 GO:0046368 GDP-L-fucose metabolic process(GO:0046368)
0.8 2.4 GO:0097401 synaptic vesicle lumen acidification(GO:0097401)
0.7 2.0 GO:1904975 response to bleomycin(GO:1904975) cellular response to bleomycin(GO:1904976)
0.6 3.5 GO:0060539 diaphragm development(GO:0060539)
0.6 1.8 GO:0019343 cysteine biosynthetic process via cystathionine(GO:0019343) cysteine biosynthetic process(GO:0019344)
0.6 1.7 GO:0045658 regulation of neutrophil differentiation(GO:0045658) negative regulation of neutrophil differentiation(GO:0045659)
0.5 2.1 GO:0060316 positive regulation of ryanodine-sensitive calcium-release channel activity(GO:0060316)
0.5 1.5 GO:1900041 intestinal D-glucose absorption(GO:0001951) negative regulation of interleukin-2 secretion(GO:1900041) terminal web assembly(GO:1902896)
0.5 1.5 GO:0019676 ammonia assimilation cycle(GO:0019676)
0.5 5.2 GO:0002315 marginal zone B cell differentiation(GO:0002315)
0.5 1.4 GO:0006116 NADH oxidation(GO:0006116) glycerol-3-phosphate catabolic process(GO:0046168)
0.5 2.3 GO:0040032 post-embryonic body morphogenesis(GO:0040032)
0.4 1.7 GO:0097374 sensory neuron axon guidance(GO:0097374)
0.4 2.2 GO:0045162 clustering of voltage-gated sodium channels(GO:0045162)
0.4 3.3 GO:0031914 negative regulation of synaptic plasticity(GO:0031914)
0.4 4.2 GO:0060501 positive regulation of epithelial cell proliferation involved in lung morphogenesis(GO:0060501)
0.4 1.1 GO:0000821 regulation of arginine metabolic process(GO:0000821)
0.3 1.0 GO:0060708 spongiotrophoblast differentiation(GO:0060708)
0.3 2.1 GO:0043137 DNA replication, removal of RNA primer(GO:0043137) positive regulation of sister chromatid cohesion(GO:0045876)
0.3 1.0 GO:0035790 platelet-derived growth factor receptor-alpha signaling pathway(GO:0035790)
0.3 2.3 GO:0070779 D-aspartate transport(GO:0070777) D-aspartate import(GO:0070779)
0.3 1.3 GO:0032382 positive regulation of intracellular lipid transport(GO:0032379) positive regulation of intracellular sterol transport(GO:0032382) positive regulation of intracellular cholesterol transport(GO:0032385) lipid hydroperoxide transport(GO:1901373)
0.3 1.2 GO:0035937 estrogen secretion(GO:0035937) estradiol secretion(GO:0035938) regulation of estrogen secretion(GO:2000861) regulation of estradiol secretion(GO:2000864)
0.3 1.5 GO:0072235 distal convoluted tubule development(GO:0072025) metanephric distal convoluted tubule development(GO:0072221) metanephric distal tubule development(GO:0072235)
0.3 1.2 GO:1902340 telomeric heterochromatin assembly(GO:0031509) negative regulation of chromosome condensation(GO:1902340)
0.3 1.4 GO:0034421 post-translational protein acetylation(GO:0034421)
0.3 0.8 GO:1904959 regulation of electron carrier activity(GO:1904732) regulation of cytochrome-c oxidase activity(GO:1904959)
0.3 1.1 GO:0061743 motor learning(GO:0061743)
0.2 1.7 GO:0033563 dorsal/ventral axon guidance(GO:0033563)
0.2 1.7 GO:0060372 regulation of atrial cardiac muscle cell membrane repolarization(GO:0060372)
0.2 0.7 GO:1902714 negative regulation of interferon-gamma secretion(GO:1902714)
0.2 1.3 GO:0036394 amylase secretion(GO:0036394)
0.2 0.7 GO:0097278 complement-dependent cytotoxicity(GO:0097278)
0.2 1.1 GO:0031580 membrane raft polarization(GO:0001766) membrane raft distribution(GO:0031580)
0.2 0.2 GO:0035880 embryonic nail plate morphogenesis(GO:0035880)
0.2 0.8 GO:0031161 phosphatidylinositol catabolic process(GO:0031161)
0.2 0.8 GO:0051643 endoplasmic reticulum localization(GO:0051643)
0.2 4.1 GO:0050774 negative regulation of dendrite morphogenesis(GO:0050774)
0.2 0.6 GO:0072718 response to cisplatin(GO:0072718)
0.2 0.5 GO:0009446 putrescine biosynthetic process(GO:0009446)
0.2 0.2 GO:2000277 positive regulation of oxidative phosphorylation uncoupler activity(GO:2000277)
0.2 0.7 GO:0072103 renal system vasculature morphogenesis(GO:0061438) kidney vasculature morphogenesis(GO:0061439) glomerulus vasculature morphogenesis(GO:0072103) glomerular capillary formation(GO:0072104)
0.2 1.9 GO:0018065 protein-cofactor linkage(GO:0018065)
0.2 1.3 GO:0018344 protein geranylgeranylation(GO:0018344)
0.2 0.8 GO:0046826 negative regulation of protein export from nucleus(GO:0046826)
0.2 1.7 GO:0035873 lactate transport(GO:0015727) lactate transmembrane transport(GO:0035873) plasma membrane lactate transport(GO:0035879)
0.2 1.2 GO:0006561 proline biosynthetic process(GO:0006561)
0.2 0.5 GO:0060672 epithelial cell differentiation involved in embryonic placenta development(GO:0060671) epithelial cell morphogenesis involved in placental branching(GO:0060672)
0.2 1.1 GO:0060124 positive regulation of growth hormone secretion(GO:0060124)
0.2 0.5 GO:1904154 positive regulation of retrograde protein transport, ER to cytosol(GO:1904154)
0.2 1.3 GO:2001214 positive regulation of vasculogenesis(GO:2001214)
0.2 1.4 GO:1990845 adaptive thermogenesis(GO:1990845)
0.1 0.6 GO:0046013 regulation of T cell homeostatic proliferation(GO:0046013) negative regulation of T-helper 17 type immune response(GO:2000317) regulation of T-helper 17 cell differentiation(GO:2000319) negative regulation of T-helper 17 cell differentiation(GO:2000320)
0.1 11.8 GO:0008543 fibroblast growth factor receptor signaling pathway(GO:0008543)
0.1 1.0 GO:0090234 regulation of centromere complex assembly(GO:0090230) regulation of kinetochore assembly(GO:0090234)
0.1 0.4 GO:1903225 regulation of endodermal cell differentiation(GO:1903224) negative regulation of endodermal cell differentiation(GO:1903225)
0.1 2.0 GO:0033234 negative regulation of protein sumoylation(GO:0033234)
0.1 2.0 GO:0097034 mitochondrial respiratory chain complex IV assembly(GO:0033617) mitochondrial respiratory chain complex IV biogenesis(GO:0097034)
0.1 0.9 GO:0010992 ubiquitin homeostasis(GO:0010992)
0.1 0.4 GO:0006419 alanyl-tRNA aminoacylation(GO:0006419)
0.1 0.4 GO:2000318 T-helper 2 cell activation(GO:0035712) positive regulation of T-helper 17 type immune response(GO:2000318) regulation of T-helper 2 cell activation(GO:2000569) positive regulation of T-helper 2 cell activation(GO:2000570)
0.1 1.1 GO:0048386 positive regulation of retinoic acid receptor signaling pathway(GO:0048386)
0.1 3.6 GO:0014046 dopamine secretion(GO:0014046) regulation of dopamine secretion(GO:0014059)
0.1 12.9 GO:0007052 mitotic spindle organization(GO:0007052)
0.1 2.4 GO:0038092 nodal signaling pathway(GO:0038092)
0.1 0.8 GO:0070474 positive regulation of uterine smooth muscle contraction(GO:0070474)
0.1 0.5 GO:0010636 positive regulation of mitochondrial fusion(GO:0010636)
0.1 0.4 GO:0021775 smoothened signaling pathway involved in ventral spinal cord interneuron specification(GO:0021775) smoothened signaling pathway involved in spinal cord motor neuron cell fate specification(GO:0021776)
0.1 0.3 GO:0072697 protein localization to cell cortex(GO:0072697)
0.1 0.4 GO:0046322 negative regulation of fatty acid oxidation(GO:0046322)
0.1 2.2 GO:0006607 NLS-bearing protein import into nucleus(GO:0006607)
0.1 3.8 GO:0021591 ventricular system development(GO:0021591)
0.1 1.8 GO:0043968 histone H2A acetylation(GO:0043968)
0.1 0.3 GO:1904578 response to thapsigargin(GO:1904578) cellular response to thapsigargin(GO:1904579)
0.1 2.9 GO:0030513 positive regulation of BMP signaling pathway(GO:0030513)
0.1 0.4 GO:0006420 arginyl-tRNA aminoacylation(GO:0006420)
0.1 0.8 GO:0032693 negative regulation of interleukin-10 production(GO:0032693)
0.1 1.9 GO:0035036 binding of sperm to zona pellucida(GO:0007339) sperm-egg recognition(GO:0035036)
0.1 1.7 GO:0006825 copper ion transport(GO:0006825)
0.1 0.6 GO:0060837 blood vessel endothelial cell differentiation(GO:0060837)
0.1 0.9 GO:0046784 viral mRNA export from host cell nucleus(GO:0046784)
0.1 1.0 GO:0043011 myeloid dendritic cell differentiation(GO:0043011)
0.1 1.0 GO:0097067 cellular response to thyroid hormone stimulus(GO:0097067)
0.1 0.3 GO:0010735 positive regulation of transcription via serum response element binding(GO:0010735)
0.1 0.2 GO:0061156 pulmonary artery morphogenesis(GO:0061156)
0.1 0.2 GO:0035864 response to potassium ion(GO:0035864) cellular response to potassium ion(GO:0035865)
0.1 0.9 GO:0031100 organ regeneration(GO:0031100)
0.1 1.3 GO:0045830 positive regulation of isotype switching(GO:0045830)
0.1 0.4 GO:0003065 positive regulation of heart rate by epinephrine(GO:0003065)
0.1 0.3 GO:0051026 chiasma assembly(GO:0051026)
0.1 3.4 GO:0006940 regulation of smooth muscle contraction(GO:0006940)
0.1 0.8 GO:0060052 neurofilament cytoskeleton organization(GO:0060052)
0.1 3.5 GO:0070303 negative regulation of stress-activated MAPK cascade(GO:0032873) negative regulation of stress-activated protein kinase signaling cascade(GO:0070303)
0.1 0.7 GO:0045899 positive regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0045899)
0.1 0.2 GO:0051533 positive regulation of NFAT protein import into nucleus(GO:0051533)
0.1 0.4 GO:1903003 positive regulation of protein deubiquitination(GO:1903003)
0.1 0.6 GO:0048096 chromatin-mediated maintenance of transcription(GO:0048096)
0.1 1.0 GO:2000269 regulation of fibroblast apoptotic process(GO:2000269)
0.1 0.2 GO:0000957 mitochondrial RNA catabolic process(GO:0000957) regulation of mitochondrial RNA catabolic process(GO:0000960)
0.1 2.6 GO:0007051 spindle organization(GO:0007051)
0.0 0.7 GO:0009125 nucleoside monophosphate catabolic process(GO:0009125)
0.0 0.1 GO:0097155 fasciculation of sensory neuron axon(GO:0097155)
0.0 0.1 GO:0002489 antigen processing and presentation of endogenous peptide antigen via MHC class Ib via ER pathway(GO:0002488) antigen processing and presentation of endogenous peptide antigen via MHC class Ib via ER pathway, TAP-dependent(GO:0002489)
0.0 1.3 GO:0035411 catenin import into nucleus(GO:0035411)
0.0 0.4 GO:0031468 nuclear envelope reassembly(GO:0031468)
0.0 0.0 GO:0002904 positive regulation of B cell apoptotic process(GO:0002904)
0.0 0.4 GO:0019430 removal of superoxide radicals(GO:0019430)
0.0 0.4 GO:0039702 cell separation after cytokinesis(GO:0000920) viral budding via host ESCRT complex(GO:0039702)
0.0 1.4 GO:0046825 regulation of protein export from nucleus(GO:0046825)
0.0 2.9 GO:0045454 cell redox homeostasis(GO:0045454)
0.0 0.3 GO:0035093 spermatogenesis, exchange of chromosomal proteins(GO:0035093)
0.0 3.4 GO:0016525 negative regulation of angiogenesis(GO:0016525)
0.0 2.2 GO:0007338 single fertilization(GO:0007338)
0.0 0.9 GO:0071425 hematopoietic stem cell proliferation(GO:0071425)
0.0 0.2 GO:0043489 RNA stabilization(GO:0043489)
0.0 0.2 GO:0051890 cardiac ventricle formation(GO:0003211) regulation of cardioblast differentiation(GO:0051890)
0.0 1.1 GO:0034723 DNA replication-dependent nucleosome assembly(GO:0006335) DNA replication-dependent nucleosome organization(GO:0034723)
0.0 1.9 GO:0006919 activation of cysteine-type endopeptidase activity involved in apoptotic process(GO:0006919)
0.0 0.9 GO:0010842 retina layer formation(GO:0010842)
0.0 0.2 GO:0021869 forebrain ventricular zone progenitor cell division(GO:0021869)
0.0 0.4 GO:0019321 pentose metabolic process(GO:0019321)
0.0 1.0 GO:0015985 energy coupled proton transport, down electrochemical gradient(GO:0015985) ATP synthesis coupled proton transport(GO:0015986)
0.0 0.1 GO:0060715 syncytiotrophoblast cell differentiation involved in labyrinthine layer development(GO:0060715)
0.0 0.5 GO:0033523 histone H2B ubiquitination(GO:0033523)
0.0 0.2 GO:2001184 regulation of interleukin-12 secretion(GO:2001182) positive regulation of interleukin-12 secretion(GO:2001184)
0.0 0.2 GO:0097152 mesenchymal cell apoptotic process(GO:0097152) regulation of mesenchymal cell apoptotic process(GO:2001053) negative regulation of mesenchymal cell apoptotic process(GO:2001054)
0.0 0.2 GO:0097475 motor neuron migration(GO:0097475)
0.0 2.6 GO:0001578 microtubule bundle formation(GO:0001578)
0.0 1.3 GO:0002011 morphogenesis of an epithelial sheet(GO:0002011)
0.0 0.5 GO:0000338 protein deneddylation(GO:0000338)
0.0 0.3 GO:1901620 regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning(GO:1901620)
0.0 0.6 GO:0051294 establishment of mitotic spindle orientation(GO:0000132) establishment of spindle orientation(GO:0051294)
0.0 1.4 GO:0043392 negative regulation of DNA binding(GO:0043392)
0.0 0.2 GO:1990481 mRNA pseudouridine synthesis(GO:1990481)
0.0 1.4 GO:0002066 columnar/cuboidal epithelial cell development(GO:0002066)
0.0 0.1 GO:0002636 positive regulation of germinal center formation(GO:0002636)
0.0 2.4 GO:0043488 regulation of mRNA stability(GO:0043488)
0.0 0.5 GO:0048026 positive regulation of mRNA splicing, via spliceosome(GO:0048026)
0.0 0.1 GO:0071688 striated muscle myosin thick filament assembly(GO:0071688)
0.0 0.3 GO:0090110 cargo loading into COPII-coated vesicle(GO:0090110)
0.0 0.3 GO:0016188 synaptic vesicle maturation(GO:0016188)
0.0 0.1 GO:0018002 N-terminal peptidyl-serine acetylation(GO:0017198) N-terminal peptidyl-glutamic acid acetylation(GO:0018002) peptidyl-serine acetylation(GO:0030920)
0.0 1.6 GO:0006635 fatty acid beta-oxidation(GO:0006635)
0.0 1.0 GO:0086010 membrane depolarization during action potential(GO:0086010)
0.0 0.1 GO:0035511 oxidative DNA demethylation(GO:0035511)
0.0 0.2 GO:0038203 TORC2 signaling(GO:0038203)
0.0 0.3 GO:0051984 positive regulation of chromosome segregation(GO:0051984)
0.0 0.4 GO:0030212 hyaluronan metabolic process(GO:0030212)
0.0 0.4 GO:0009566 fertilization(GO:0009566)
0.0 0.7 GO:0006376 mRNA splice site selection(GO:0006376)
0.0 0.1 GO:0052490 suppression by virus of host apoptotic process(GO:0019050) negative regulation by symbiont of host apoptotic process(GO:0033668) modulation by virus of host apoptotic process(GO:0039526) response to cycloheximide(GO:0046898) negative regulation by symbiont of host programmed cell death(GO:0052041) modulation by symbiont of host apoptotic process(GO:0052150) negative regulation by organism of programmed cell death in other organism involved in symbiotic interaction(GO:0052490) cellular process regulating host cell cycle in response to virus(GO:0060154)
0.0 2.8 GO:0051321 meiotic cell cycle(GO:0051321)
0.0 0.3 GO:0006465 signal peptide processing(GO:0006465)
0.0 0.4 GO:0070534 protein K63-linked ubiquitination(GO:0070534)
0.0 0.3 GO:0006767 water-soluble vitamin metabolic process(GO:0006767)
0.0 0.1 GO:0006122 mitochondrial electron transport, ubiquinol to cytochrome c(GO:0006122)
0.0 0.5 GO:0042773 ATP synthesis coupled electron transport(GO:0042773)
0.0 0.5 GO:0048013 ephrin receptor signaling pathway(GO:0048013)
0.0 0.2 GO:0006614 SRP-dependent cotranslational protein targeting to membrane(GO:0006614)
0.0 0.4 GO:0016925 protein sumoylation(GO:0016925)
0.0 4.3 GO:0051301 cell division(GO:0051301)
0.0 1.3 GO:0046488 phosphatidylinositol metabolic process(GO:0046488)
0.0 0.3 GO:0048701 embryonic cranial skeleton morphogenesis(GO:0048701)
0.0 0.3 GO:0032011 ARF protein signal transduction(GO:0032011) regulation of ARF protein signal transduction(GO:0032012)
0.0 2.4 GO:0007283 spermatogenesis(GO:0007283)
0.0 0.0 GO:0032914 transforming growth factor beta1 production(GO:0032905) regulation of transforming growth factor beta1 production(GO:0032908) positive regulation of transforming growth factor beta1 production(GO:0032914) eye pigmentation(GO:0048069)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
2.7 16.2 GO:0031262 Ndc80 complex(GO:0031262)
1.2 15.0 GO:0097542 ciliary tip(GO:0097542)
0.6 3.3 GO:0044305 calyx of Held(GO:0044305)
0.5 4.6 GO:0030478 actin cap(GO:0030478)
0.5 2.0 GO:0002111 BRCA2-BRAF35 complex(GO:0002111)
0.4 3.4 GO:0097427 microtubule bundle(GO:0097427)
0.4 1.5 GO:0097454 Schwann cell microvillus(GO:0097454)
0.3 1.4 GO:0009331 glycerol-3-phosphate dehydrogenase complex(GO:0009331)
0.3 0.8 GO:0044614 nuclear pore cytoplasmic filaments(GO:0044614)
0.3 1.3 GO:0005968 Rab-protein geranylgeranyltransferase complex(GO:0005968)
0.3 1.3 GO:0031466 Cul5-RING ubiquitin ligase complex(GO:0031466)
0.2 2.2 GO:0000805 X chromosome(GO:0000805)
0.2 2.0 GO:0031390 Ctf18 RFC-like complex(GO:0031390)
0.2 2.8 GO:0042788 polysomal ribosome(GO:0042788)
0.2 1.1 GO:0000172 ribonuclease MRP complex(GO:0000172)
0.2 3.4 GO:0000800 lateral element(GO:0000800)
0.2 1.4 GO:0001520 outer dense fiber(GO:0001520)
0.2 1.3 GO:0031315 extrinsic component of mitochondrial outer membrane(GO:0031315)
0.1 0.8 GO:0000938 GARP complex(GO:0000938)
0.1 1.3 GO:0032591 dendritic spine membrane(GO:0032591)
0.1 0.4 GO:0005588 collagen type V trimer(GO:0005588)
0.1 0.7 GO:0033093 multivesicular body membrane(GO:0032585) Weibel-Palade body(GO:0033093)
0.1 1.7 GO:0070852 cell body fiber(GO:0070852)
0.1 1.8 GO:0031011 Ino80 complex(GO:0031011)
0.1 2.4 GO:0044300 cerebellar mossy fiber(GO:0044300)
0.1 10.7 GO:0072562 blood microparticle(GO:0072562)
0.1 1.1 GO:0008541 proteasome regulatory particle, lid subcomplex(GO:0008541)
0.1 0.6 GO:0031595 nuclear proteasome complex(GO:0031595)
0.1 0.9 GO:0000347 THO complex(GO:0000347) THO complex part of transcription export complex(GO:0000445)
0.1 2.5 GO:0031307 integral component of mitochondrial outer membrane(GO:0031307)
0.1 0.7 GO:0089701 U2AF(GO:0089701)
0.1 6.5 GO:0005776 autophagosome(GO:0005776)
0.1 4.2 GO:0097610 cleavage furrow(GO:0032154) cell surface furrow(GO:0097610)
0.1 1.0 GO:0000276 mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276)
0.1 2.3 GO:0032588 trans-Golgi network membrane(GO:0032588)
0.1 2.6 GO:0005868 cytoplasmic dynein complex(GO:0005868)
0.1 1.0 GO:0016460 myosin II complex(GO:0016460)
0.1 1.1 GO:0097470 ribbon synapse(GO:0097470)
0.1 2.6 GO:0030173 integral component of Golgi membrane(GO:0030173)
0.1 2.3 GO:0042734 presynaptic membrane(GO:0042734)
0.0 1.4 GO:0000788 nuclear nucleosome(GO:0000788)
0.0 1.1 GO:0043218 compact myelin(GO:0043218)
0.0 0.4 GO:0000815 ESCRT III complex(GO:0000815)
0.0 1.3 GO:0043194 axon initial segment(GO:0043194)
0.0 1.5 GO:0035861 site of double-strand break(GO:0035861)
0.0 0.4 GO:0043240 Fanconi anaemia nuclear complex(GO:0043240)
0.0 0.4 GO:0005862 muscle thin filament tropomyosin(GO:0005862)
0.0 0.5 GO:0031464 Cul4A-RING E3 ubiquitin ligase complex(GO:0031464)
0.0 0.3 GO:0005787 signal peptidase complex(GO:0005787)
0.0 0.3 GO:0016593 Cdc73/Paf1 complex(GO:0016593)
0.0 0.2 GO:0071556 integral component of cytoplasmic side of endoplasmic reticulum membrane(GO:0071458) integral component of lumenal side of endoplasmic reticulum membrane(GO:0071556) lumenal side of endoplasmic reticulum membrane(GO:0098553)
0.0 0.5 GO:0030127 COPII vesicle coat(GO:0030127)
0.0 0.3 GO:0000795 synaptonemal complex(GO:0000795)
0.0 2.3 GO:0005643 nuclear pore(GO:0005643)
0.0 0.5 GO:0005782 peroxisomal matrix(GO:0005782) microbody lumen(GO:0031907)
0.0 1.9 GO:0005758 mitochondrial intermembrane space(GO:0005758)
0.0 0.9 GO:0035145 exon-exon junction complex(GO:0035145)
0.0 3.6 GO:0043296 apical junction complex(GO:0043296)
0.0 0.8 GO:0060077 inhibitory synapse(GO:0060077)
0.0 2.7 GO:0000922 spindle pole(GO:0000922)
0.0 0.8 GO:0032590 dendrite membrane(GO:0032590)
0.0 2.0 GO:0001669 acrosomal vesicle(GO:0001669)
0.0 0.1 GO:0042824 MHC class I peptide loading complex(GO:0042824) TAP complex(GO:0042825)
0.0 0.2 GO:0016327 apicolateral plasma membrane(GO:0016327)
0.0 1.2 GO:0005881 cytoplasmic microtubule(GO:0005881)
0.0 0.3 GO:0005876 spindle microtubule(GO:0005876)
0.0 0.3 GO:0030008 TRAPP complex(GO:0030008)
0.0 2.0 GO:0000776 kinetochore(GO:0000776)
0.0 3.3 GO:0043679 axon terminus(GO:0043679)
0.0 0.5 GO:0097546 ciliary base(GO:0097546)
0.0 0.5 GO:0016459 myosin complex(GO:0016459)
0.0 1.1 GO:0070469 respiratory chain(GO:0070469)
0.0 0.5 GO:0008180 COP9 signalosome(GO:0008180)
0.0 0.1 GO:0031415 NatA complex(GO:0031415)
0.0 0.6 GO:0008023 transcription elongation factor complex(GO:0008023)
0.0 0.3 GO:0080008 Cul4-RING E3 ubiquitin ligase complex(GO:0080008)
0.0 0.4 GO:0000786 nucleosome(GO:0000786)
0.0 0.5 GO:0005871 kinesin complex(GO:0005871)
0.0 6.5 GO:0005856 cytoskeleton(GO:0005856)
0.0 0.2 GO:0031932 TORC2 complex(GO:0031932)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
2.3 25.7 GO:0019992 diacylglycerol binding(GO:0019992)
1.7 5.2 GO:0033829 O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase activity(GO:0033829)
0.9 7.5 GO:0048403 brain-derived neurotrophic factor binding(GO:0048403)
0.8 2.4 GO:0005436 sodium:phosphate symporter activity(GO:0005436) sodium:inorganic phosphate symporter activity(GO:0015319)
0.7 14.4 GO:0001848 complement binding(GO:0001848)
0.5 2.2 GO:0008802 betaine-aldehyde dehydrogenase activity(GO:0008802)
0.5 1.4 GO:0016901 glycerol-3-phosphate dehydrogenase activity(GO:0004368) oxidoreductase activity, acting on the CH-OH group of donors, quinone or similar compound as acceptor(GO:0016901)
0.4 2.2 GO:0086080 protein binding involved in heterotypic cell-cell adhesion(GO:0086080)
0.4 1.7 GO:0016842 amidine-lyase activity(GO:0016842)
0.4 15.0 GO:1990841 promoter-specific chromatin binding(GO:1990841)
0.4 2.1 GO:0017108 5'-flap endonuclease activity(GO:0017108)
0.4 3.3 GO:0001135 transcription factor activity, RNA polymerase II transcription factor recruiting(GO:0001135)
0.4 2.3 GO:0015501 glutamate:sodium symporter activity(GO:0015501)
0.4 2.3 GO:0051429 corticotropin-releasing hormone receptor binding(GO:0051429) corticotropin-releasing hormone receptor 1 binding(GO:0051430)
0.4 1.1 GO:0000171 ribonuclease MRP activity(GO:0000171)
0.3 1.4 GO:0017077 oxidative phosphorylation uncoupler activity(GO:0017077)
0.3 1.7 GO:0004165 dodecenoyl-CoA delta-isomerase activity(GO:0004165)
0.3 1.6 GO:0004322 ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724)
0.3 10.2 GO:0051183 vitamin transporter activity(GO:0051183)
0.3 1.3 GO:0050632 propanoyl-CoA C-acyltransferase activity(GO:0033814) propionyl-CoA C2-trimethyltridecanoyltransferase activity(GO:0050632) phosphatidylethanolamine transporter activity(GO:1904121)
0.3 1.2 GO:0034647 histone demethylase activity (H3-trimethyl-K4 specific)(GO:0034647)
0.3 1.2 GO:0004735 pyrroline-5-carboxylate reductase activity(GO:0004735)
0.3 2.0 GO:0051880 G-quadruplex DNA binding(GO:0051880)
0.3 11.6 GO:0042169 SH2 domain binding(GO:0042169)
0.2 1.0 GO:0072345 NAADP-sensitive calcium-release channel activity(GO:0072345)
0.2 0.7 GO:0048019 receptor antagonist activity(GO:0048019)
0.2 1.8 GO:0016846 carbon-sulfur lyase activity(GO:0016846)
0.2 1.7 GO:0048495 Roundabout binding(GO:0048495)
0.2 1.7 GO:0086008 voltage-gated potassium channel activity involved in cardiac muscle cell action potential repolarization(GO:0086008)
0.2 1.3 GO:0061649 ubiquitinated histone binding(GO:0061649)
0.2 5.2 GO:0043014 alpha-tubulin binding(GO:0043014)
0.2 0.5 GO:0046592 polyamine oxidase activity(GO:0046592) spermine:oxygen oxidoreductase (spermidine-forming) activity(GO:0052901)
0.2 2.4 GO:0055106 ubiquitin-protein transferase regulator activity(GO:0055106)
0.2 3.0 GO:0004435 phosphatidylinositol phospholipase C activity(GO:0004435)
0.2 2.0 GO:0070513 death domain binding(GO:0070513)
0.1 0.7 GO:0016936 galactoside binding(GO:0016936)
0.1 2.9 GO:0015035 protein disulfide oxidoreductase activity(GO:0015035)
0.1 1.1 GO:0016618 hydroxypyruvate reductase activity(GO:0016618) glyoxylate reductase (NADP) activity(GO:0030267)
0.1 0.8 GO:0004852 uroporphyrinogen-III synthase activity(GO:0004852)
0.1 1.1 GO:0019911 structural constituent of myelin sheath(GO:0019911)
0.1 0.3 GO:0000403 Y-form DNA binding(GO:0000403)
0.1 2.9 GO:0034237 protein kinase A regulatory subunit binding(GO:0034237)
0.1 0.4 GO:0017099 very-long-chain-acyl-CoA dehydrogenase activity(GO:0017099)
0.1 0.9 GO:0001162 RNA polymerase II intronic transcription regulatory region sequence-specific DNA binding(GO:0001162)
0.1 0.4 GO:0004813 alanine-tRNA ligase activity(GO:0004813)
0.1 1.4 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.1 1.1 GO:0061133 endopeptidase activator activity(GO:0061133)
0.1 0.6 GO:0005134 interleukin-2 receptor binding(GO:0005134)
0.1 0.8 GO:1903136 cuprous ion binding(GO:1903136)
0.1 0.3 GO:0031750 D3 dopamine receptor binding(GO:0031750)
0.1 2.0 GO:0000400 four-way junction DNA binding(GO:0000400)
0.1 0.3 GO:0003996 acyl-CoA ligase activity(GO:0003996)
0.1 0.6 GO:0036402 proteasome-activating ATPase activity(GO:0036402)
0.1 0.4 GO:0004814 arginine-tRNA ligase activity(GO:0004814)
0.1 4.1 GO:0031492 nucleosomal DNA binding(GO:0031492)
0.1 0.3 GO:1990269 RNA polymerase II C-terminal domain phosphoserine binding(GO:1990269)
0.1 0.8 GO:0016004 phospholipase activator activity(GO:0016004) lipase activator activity(GO:0060229)
0.1 1.1 GO:0015174 basic amino acid transmembrane transporter activity(GO:0015174)
0.1 2.8 GO:0017091 AU-rich element binding(GO:0017091)
0.1 1.0 GO:0016929 SUMO-specific protease activity(GO:0016929)
0.1 0.3 GO:0030983 mismatched DNA binding(GO:0030983)
0.1 0.6 GO:0031681 G-protein beta-subunit binding(GO:0031681)
0.1 1.9 GO:0008139 nuclear localization sequence binding(GO:0008139)
0.1 1.4 GO:0005092 GDP-dissociation inhibitor activity(GO:0005092)
0.1 1.1 GO:0035497 cAMP response element binding(GO:0035497)
0.1 4.1 GO:0097110 scaffold protein binding(GO:0097110)
0.1 1.8 GO:0044183 protein binding involved in protein folding(GO:0044183)
0.1 0.5 GO:0004571 mannosyl-oligosaccharide 1,2-alpha-mannosidase activity(GO:0004571)
0.1 0.3 GO:0016778 diphosphotransferase activity(GO:0016778)
0.0 0.7 GO:0030628 pre-mRNA 3'-splice site binding(GO:0030628)
0.0 0.2 GO:0003680 AT DNA binding(GO:0003680)
0.0 1.1 GO:0050136 NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.0 0.8 GO:0008188 neuropeptide receptor activity(GO:0008188)
0.0 3.5 GO:0001158 enhancer sequence-specific DNA binding(GO:0001158)
0.0 0.1 GO:0031798 type 1 metabotropic glutamate receptor binding(GO:0031798) RNA polymerase II transcription factor activity, estrogen-activated sequence-specific DNA binding(GO:0038052)
0.0 0.8 GO:1900750 glutathione binding(GO:0043295) oligopeptide binding(GO:1900750)
0.0 0.1 GO:0015433 peptide antigen-transporting ATPase activity(GO:0015433) tapasin binding(GO:0046980)
0.0 0.4 GO:0031386 protein tag(GO:0031386)
0.0 0.7 GO:0070410 co-SMAD binding(GO:0070410)
0.0 0.1 GO:0051747 cytosine C-5 DNA demethylase activity(GO:0051747)
0.0 2.1 GO:0004722 protein serine/threonine phosphatase activity(GO:0004722)
0.0 0.6 GO:0016799 hydrolase activity, hydrolyzing N-glycosyl compounds(GO:0016799)
0.0 0.6 GO:0032454 histone demethylase activity (H3-K9 specific)(GO:0032454)
0.0 5.7 GO:0051015 actin filament binding(GO:0051015)
0.0 0.8 GO:0008536 Ran GTPase binding(GO:0008536)
0.0 0.6 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.0 0.3 GO:0043522 leucine zipper domain binding(GO:0043522)
0.0 0.9 GO:0042162 telomeric DNA binding(GO:0042162)
0.0 0.5 GO:0004129 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.0 1.0 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.0 0.1 GO:1990190 peptide-glutamate-N-acetyltransferase activity(GO:1990190)
0.0 1.6 GO:0003697 single-stranded DNA binding(GO:0003697)
0.0 0.2 GO:0042500 aspartic endopeptidase activity, intramembrane cleaving(GO:0042500)
0.0 0.1 GO:1990247 N6-methyladenosine-containing RNA binding(GO:1990247)
0.0 0.3 GO:0071837 HMG box domain binding(GO:0071837)
0.0 0.2 GO:0004190 aspartic-type endopeptidase activity(GO:0004190) aspartic-type peptidase activity(GO:0070001)
0.0 1.2 GO:0019842 vitamin binding(GO:0019842)
0.0 0.9 GO:0031490 chromatin DNA binding(GO:0031490)
0.0 0.2 GO:0015217 ATP transmembrane transporter activity(GO:0005347) ADP transmembrane transporter activity(GO:0015217)
0.0 2.2 GO:0016779 nucleotidyltransferase activity(GO:0016779)
0.0 0.1 GO:0016300 tRNA (uracil) methyltransferase activity(GO:0016300)
0.0 1.1 GO:0061733 peptide-lysine-N-acetyltransferase activity(GO:0061733)
0.0 0.1 GO:0005005 transmembrane-ephrin receptor activity(GO:0005005) PH domain binding(GO:0042731)
0.0 0.3 GO:0003950 NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.0 0.4 GO:0004697 protein kinase C activity(GO:0004697)
0.0 0.3 GO:0051539 4 iron, 4 sulfur cluster binding(GO:0051539)
0.0 1.7 GO:0004386 helicase activity(GO:0004386)
0.0 0.3 GO:0031489 myosin V binding(GO:0031489)
0.0 0.3 GO:0019707 protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)
0.0 0.2 GO:0009982 pseudouridine synthase activity(GO:0009982)
0.0 2.8 GO:0003779 actin binding(GO:0003779)
0.0 0.4 GO:0019200 carbohydrate kinase activity(GO:0019200)
0.0 9.4 GO:0043565 sequence-specific DNA binding(GO:0043565)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 22.1 PID_RAS_PATHWAY Regulation of Ras family activation
0.5 15.0 PID_HEDGEHOG_2PATHWAY Signaling events mediated by the Hedgehog family
0.2 5.8 NABA_PROTEOGLYCANS Genes encoding proteoglycans
0.1 6.0 PID_PLK1_PATHWAY PLK1 signaling events
0.1 13.3 NABA_ECM_REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.1 2.0 PID_SMAD2_3PATHWAY Regulation of cytoplasmic and nuclear SMAD2/3 signaling
0.1 0.8 PID_RANBP2_PATHWAY Sumoylation by RanBP2 regulates transcriptional repression
0.1 3.8 PID_RHOA_PATHWAY RhoA signaling pathway
0.1 1.9 PID_MAPK_TRK_PATHWAY Trk receptor signaling mediated by the MAPK pathway
0.1 2.4 PID_SMAD2_3NUCLEAR_PATHWAY Regulation of nuclear SMAD2/3 signaling
0.1 1.9 PID_TCR_CALCIUM_PATHWAY Calcium signaling in the CD4+ TCR pathway
0.1 1.8 PID_MYC_PATHWAY C-MYC pathway
0.1 1.9 PID_P38_MK2_PATHWAY p38 signaling mediated by MAPKAP kinases
0.0 1.8 PID_HNF3B_PATHWAY FOXA2 and FOXA3 transcription factor networks
0.0 0.8 PID_IL8_CXCR1_PATHWAY IL8- and CXCR1-mediated signaling events
0.0 0.9 PID_WNT_SIGNALING_PATHWAY Wnt signaling network
0.0 0.5 PID_INTEGRIN_A9B1_PATHWAY Alpha9 beta1 integrin signaling events
0.0 0.6 PID_P38_MKK3_6PATHWAY p38 MAPK signaling pathway
0.0 1.2 PID_AJDISS_2PATHWAY Posttranslational regulation of adherens junction stability and dissassembly
0.0 0.4 PID_NFAT_3PATHWAY Role of Calcineurin-dependent NFAT signaling in lymphocytes
0.0 0.7 PID_FCER1_PATHWAY Fc-epsilon receptor I signaling in mast cells
0.0 0.4 PID_BARD1_PATHWAY BARD1 signaling events
0.0 0.4 PID_FOXM1_PATHWAY FOXM1 transcription factor network
0.0 0.4 PID_INTEGRIN1_PATHWAY Beta1 integrin cell surface interactions

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
1.4 14.4 REACTOME_INTRINSIC_PATHWAY Genes involved in Intrinsic Pathway
0.7 22.7 REACTOME_EFFECTS_OF_PIP2_HYDROLYSIS Genes involved in Effects of PIP2 hydrolysis
0.3 5.9 REACTOME_PRE_NOTCH_PROCESSING_IN_GOLGI Genes involved in Pre-NOTCH Processing in Golgi
0.2 2.1 REACTOME_REMOVAL_OF_THE_FLAP_INTERMEDIATE_FROM_THE_C_STRAND Genes involved in Removal of the Flap Intermediate from the C-strand
0.2 18.3 REACTOME_MITOTIC_PROMETAPHASE Genes involved in Mitotic Prometaphase
0.1 3.2 REACTOME_KINESINS Genes involved in Kinesins
0.1 5.3 REACTOME_SMOOTH_MUSCLE_CONTRACTION Genes involved in Smooth Muscle Contraction
0.1 2.1 REACTOME_MITOCHONDRIAL_FATTY_ACID_BETA_OXIDATION Genes involved in Mitochondrial Fatty Acid Beta-Oxidation
0.1 1.3 REACTOME_SYNTHESIS_OF_BILE_ACIDS_AND_BILE_SALTS_VIA_7ALPHA_HYDROXYCHOLESTEROL Genes involved in Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol
0.1 5.8 REACTOME_AMINO_ACID_AND_OLIGOPEPTIDE_SLC_TRANSPORTERS Genes involved in Amino acid and oligopeptide SLC transporters
0.1 0.8 REACTOME_REGULATION_OF_INSULIN_SECRETION_BY_ACETYLCHOLINE Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.1 2.4 REACTOME_OTHER_SEMAPHORIN_INTERACTIONS Genes involved in Other semaphorin interactions
0.1 1.9 REACTOME_SIGNALLING_TO_P38_VIA_RIT_AND_RIN Genes involved in Signalling to p38 via RIT and RIN
0.1 3.1 REACTOME_DOWNREGULATION_OF_SMAD2_3_SMAD4_TRANSCRIPTIONAL_ACTIVITY Genes involved in Downregulation of SMAD2/3:SMAD4 transcriptional activity
0.1 3.7 REACTOME_ACTIVATION_OF_CHAPERONE_GENES_BY_XBP1S Genes involved in Activation of Chaperone Genes by XBP1(S)
0.1 2.3 REACTOME_PROSTACYCLIN_SIGNALLING_THROUGH_PROSTACYCLIN_RECEPTOR Genes involved in Prostacyclin signalling through prostacyclin receptor
0.1 1.6 REACTOME_METAL_ION_SLC_TRANSPORTERS Genes involved in Metal ion SLC transporters
0.1 0.6 REACTOME_HYALURONAN_UPTAKE_AND_DEGRADATION Genes involved in Hyaluronan uptake and degradation
0.1 0.5 REACTOME_METABOLISM_OF_POLYAMINES Genes involved in Metabolism of polyamines
0.1 2.6 REACTOME_RNA_POL_I_PROMOTER_OPENING Genes involved in RNA Polymerase I Promoter Opening
0.0 1.0 REACTOME_SULFUR_AMINO_ACID_METABOLISM Genes involved in Sulfur amino acid metabolism
0.0 0.3 REACTOME_FGFR4_LIGAND_BINDING_AND_ACTIVATION Genes involved in FGFR4 ligand binding and activation
0.0 1.4 REACTOME_INTERACTION_BETWEEN_L1_AND_ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.0 1.4 REACTOME_MYOGENESIS Genes involved in Myogenesis
0.0 1.5 REACTOME_RECYCLING_PATHWAY_OF_L1 Genes involved in Recycling pathway of L1
0.0 2.3 REACTOME_ANTIVIRAL_MECHANISM_BY_IFN_STIMULATED_GENES Genes involved in Antiviral mechanism by IFN-stimulated genes
0.0 4.3 REACTOME_METABOLISM_OF_AMINO_ACIDS_AND_DERIVATIVES Genes involved in Metabolism of amino acids and derivatives
0.0 0.8 REACTOME_TIGHT_JUNCTION_INTERACTIONS Genes involved in Tight junction interactions
0.0 0.9 REACTOME_TRAFFICKING_OF_AMPA_RECEPTORS Genes involved in Trafficking of AMPA receptors
0.0 0.4 REACTOME_ANTIGEN_PRESENTATION_FOLDING_ASSEMBLY_AND_PEPTIDE_LOADING_OF_CLASS_I_MHC Genes involved in Antigen Presentation: Folding, assembly and peptide loading of class I MHC
0.0 2.0 REACTOME_RESPIRATORY_ELECTRON_TRANSPORT_ATP_SYNTHESIS_BY_CHEMIOSMOTIC_COUPLING_AND_HEAT_PRODUCTION_BY_UNCOUPLING_PROTEINS_ Genes involved in Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins.
0.0 0.4 REACTOME_FANCONI_ANEMIA_PATHWAY Genes involved in Fanconi Anemia pathway
0.0 0.3 REACTOME_SYNTHESIS_SECRETION_AND_INACTIVATION_OF_GIP Genes involved in Synthesis, Secretion, and Inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)
0.0 0.6 REACTOME_IL_RECEPTOR_SHC_SIGNALING Genes involved in Interleukin receptor SHC signaling
0.0 0.2 REACTOME_INTERACTIONS_OF_VPR_WITH_HOST_CELLULAR_PROTEINS Genes involved in Interactions of Vpr with host cellular proteins
0.0 0.3 REACTOME_MEIOTIC_RECOMBINATION Genes involved in Meiotic Recombination
0.0 0.4 REACTOME_ENDOSOMAL_SORTING_COMPLEX_REQUIRED_FOR_TRANSPORT_ESCRT Genes involved in Endosomal Sorting Complex Required For Transport (ESCRT)
0.0 0.5 REACTOME_MITOCHONDRIAL_PROTEIN_IMPORT Genes involved in Mitochondrial Protein Import