Motif ID: Hoxa5

Z-value: 0.716


Transcription factors associated with Hoxa5:

Gene SymbolEntrez IDGene Name
Hoxa5 ENSMUSG00000038253.6 Hoxa5



Activity profile for motif Hoxa5.

activity profile for motif Hoxa5


Sorted Z-values histogram for motif Hoxa5

Sorted Z-values for motif Hoxa5



Network of associatons between targets according to the STRING database.



First level regulatory network of Hoxa5

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr5_+_17574268 4.063 ENSMUST00000030568.7
Sema3c
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C
chr5_+_17574726 2.818 ENSMUST00000169603.1
Sema3c
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C
chr16_+_43508118 2.611 ENSMUST00000114690.1
Zbtb20
zinc finger and BTB domain containing 20
chrX_+_66653003 1.915 ENSMUST00000036043.4
Slitrk2
SLIT and NTRK-like family, member 2
chr9_-_58313189 1.874 ENSMUST00000061799.8
Loxl1
lysyl oxidase-like 1
chr16_+_43247278 1.598 ENSMUST00000114691.1
ENSMUST00000079441.6
Zbtb20

zinc finger and BTB domain containing 20

chr5_+_3343893 1.484 ENSMUST00000165117.1
Cdk6
cyclin-dependent kinase 6
chr3_+_62419668 1.462 ENSMUST00000161057.1
Arhgef26
Rho guanine nucleotide exchange factor (GEF) 26
chr8_-_99416397 1.398 ENSMUST00000155527.1
ENSMUST00000142129.1
ENSMUST00000093249.4
ENSMUST00000142475.2
ENSMUST00000128860.1
Cdh8




cadherin 8




chrY_+_1010543 1.391 ENSMUST00000091197.3
Eif2s3y
eukaryotic translation initiation factor 2, subunit 3, structural gene Y-linked
chrY_-_1286563 1.331 ENSMUST00000091190.5
Ddx3y
DEAD (Asp-Glu-Ala-Asp) box polypeptide 3, Y-linked
chr1_+_104768510 1.290 ENSMUST00000062528.8
Cdh20
cadherin 20
chr3_-_116968969 1.269 ENSMUST00000143611.1
ENSMUST00000040097.7
Palmd

palmdelphin

chr4_+_128846163 1.247 ENSMUST00000138291.1
Gm12968
predicted gene 12968
chr1_+_169655493 1.227 ENSMUST00000027997.3
Rgs5
regulator of G-protein signaling 5
chr11_+_16752203 1.195 ENSMUST00000102884.3
ENSMUST00000020329.6
Egfr

epidermal growth factor receptor

chr5_-_62766153 1.136 ENSMUST00000076623.4
Arap2
ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2
chr8_+_57455898 1.050 ENSMUST00000034023.3
Scrg1
scrapie responsive gene 1
chr6_+_17463749 1.035 ENSMUST00000115443.1
Met
met proto-oncogene
chr17_-_31636631 0.968 ENSMUST00000135425.1
ENSMUST00000151718.1
ENSMUST00000155814.1
Cbs


cystathionine beta-synthase


chr2_+_4400958 0.928 ENSMUST00000075767.7
Frmd4a
FERM domain containing 4A
chr7_+_81523531 0.900 ENSMUST00000181903.1
2900076A07Rik
RIKEN cDNA 2900076A07 gene
chr12_+_32953874 0.897 ENSMUST00000076698.5
Sypl
synaptophysin-like protein
chr13_-_81710937 0.876 ENSMUST00000161920.1
ENSMUST00000048993.5
Polr3g

polymerase (RNA) III (DNA directed) polypeptide G

chr19_-_28963863 0.863 ENSMUST00000161813.1
4430402I18Rik
RIKEN cDNA 4430402I18 gene
chr10_+_128933782 0.853 ENSMUST00000099112.2
Itga7
integrin alpha 7
chr5_+_66968559 0.848 ENSMUST00000127184.1
Limch1
LIM and calponin homology domains 1
chr9_+_37367354 0.844 ENSMUST00000051839.7
Hepacam
hepatocyte cell adhesion molecule
chr5_+_66968416 0.837 ENSMUST00000038188.7
Limch1
LIM and calponin homology domains 1
chr10_+_57784914 0.822 ENSMUST00000165013.1
Fabp7
fatty acid binding protein 7, brain
chr6_+_103510874 0.779 ENSMUST00000066905.6
Chl1
cell adhesion molecule with homology to L1CAM
chr16_-_37384915 0.767 ENSMUST00000114787.1
ENSMUST00000114782.1
ENSMUST00000023526.2
ENSMUST00000114775.1
Stxbp5l



syntaxin binding protein 5-like



chr2_-_76673039 0.758 ENSMUST00000002809.7
Fkbp7
FK506 binding protein 7
chr8_+_71887264 0.750 ENSMUST00000034259.7
Zfp709
zinc finger protein 709
chr8_+_23411490 0.746 ENSMUST00000033952.7
Sfrp1
secreted frizzled-related protein 1
chr13_+_94083490 0.736 ENSMUST00000156071.1
Lhfpl2
lipoma HMGIC fusion partner-like 2
chr5_+_104459450 0.731 ENSMUST00000086831.3
Pkd2
polycystic kidney disease 2
chr17_-_81649607 0.693 ENSMUST00000163680.2
ENSMUST00000086538.3
ENSMUST00000163123.1
Slc8a1


solute carrier family 8 (sodium/calcium exchanger), member 1


chr8_+_84908560 0.690 ENSMUST00000003910.6
ENSMUST00000109744.1
Dnase2a

deoxyribonuclease II alpha

chr15_-_98677451 0.689 ENSMUST00000120997.1
ENSMUST00000109149.2
ENSMUST00000003451.4
Rnd1


Rho family GTPase 1


chr7_+_81523555 0.672 ENSMUST00000180385.1
ENSMUST00000180879.1
ENSMUST00000181164.1
ENSMUST00000181264.1
2900076A07Rik



RIKEN cDNA 2900076A07 gene



chr2_-_33942111 0.669 ENSMUST00000130988.1
ENSMUST00000127936.1
ENSMUST00000134271.1
Gm13403


predicted gene 13403


chr2_-_175131864 0.665 ENSMUST00000108929.2
Gm14399
predicted gene 14399
chr10_-_83648713 0.658 ENSMUST00000020500.7
Appl2
adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 2
chr8_+_66386292 0.655 ENSMUST00000039540.5
ENSMUST00000110253.2
March1

membrane-associated ring finger (C3HC4) 1

chr12_-_48559971 0.652 ENSMUST00000169406.1
Gm1818
predicted gene 1818
chr5_+_13398688 0.643 ENSMUST00000125629.1
Sema3a
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A
chr12_+_102554966 0.631 ENSMUST00000021610.5
Chga
chromogranin A
chr2_+_83812567 0.622 ENSMUST00000051454.3
Fam171b
family with sequence similarity 171, member B
chr9_-_51278540 0.620 ENSMUST00000114427.3
Gm684
predicted gene 684
chr18_+_37447641 0.610 ENSMUST00000052387.3
Pcdhb14
protocadherin beta 14
chrX_-_103821940 0.598 ENSMUST00000042664.5
Slc16a2
solute carrier family 16 (monocarboxylic acid transporters), member 2
chr10_-_80329426 0.589 ENSMUST00000020340.8
Pcsk4
proprotein convertase subtilisin/kexin type 4
chr16_-_37384940 0.582 ENSMUST00000114781.1
ENSMUST00000114780.1
Stxbp5l

syntaxin binding protein 5-like

chr13_+_23763660 0.578 ENSMUST00000055770.1
Hist1h1a
histone cluster 1, H1a
chr11_-_69795930 0.574 ENSMUST00000045971.8
Chrnb1
cholinergic receptor, nicotinic, beta polypeptide 1 (muscle)
chr4_+_123016590 0.573 ENSMUST00000102649.3
Trit1
tRNA isopentenyltransferase 1
chr2_+_4300462 0.570 ENSMUST00000175669.1
Frmd4a
FERM domain containing 4A
chr12_+_81631369 0.570 ENSMUST00000036116.5
Ttc9
tetratricopeptide repeat domain 9
chr5_-_69590783 0.564 ENSMUST00000173927.1
Gnpda2
glucosamine-6-phosphate deaminase 2
chr6_-_60829826 0.564 ENSMUST00000163779.1
Snca
synuclein, alpha
chr2_-_63184253 0.556 ENSMUST00000075052.3
ENSMUST00000112454.1
Kcnh7

potassium voltage-gated channel, subfamily H (eag-related), member 7

chr6_+_21949571 0.553 ENSMUST00000031680.3
ENSMUST00000115389.1
ENSMUST00000151473.1
Ing3


inhibitor of growth family, member 3


chr17_-_78937031 0.551 ENSMUST00000024885.8
Cebpz
CCAAT/enhancer binding protein zeta
chr6_+_72097561 0.547 ENSMUST00000069994.4
ENSMUST00000114112.1
St3gal5

ST3 beta-galactoside alpha-2,3-sialyltransferase 5

chr7_-_46099752 0.528 ENSMUST00000180081.1
Kcnj11
potassium inwardly rectifying channel, subfamily J, member 11
chr11_-_48826500 0.527 ENSMUST00000161192.2
Gm12184
predicted gene 12184
chr7_+_18987518 0.501 ENSMUST00000063563.7
Nanos2
nanos homolog 2 (Drosophila)
chr3_-_59344256 0.495 ENSMUST00000039419.6
Igsf10
immunoglobulin superfamily, member 10
chr10_-_83648631 0.480 ENSMUST00000146876.2
ENSMUST00000176294.1
Appl2

adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 2

chr17_-_21908092 0.476 ENSMUST00000106026.2
2210404O09Rik
RIKEN cDNA 2210404O09 gene
chr2_+_84734050 0.475 ENSMUST00000090729.2
Ypel4
yippee-like 4 (Drosophila)
chr8_+_82863351 0.458 ENSMUST00000078525.5
Rnf150
ring finger protein 150
chr10_+_58255465 0.456 ENSMUST00000057659.7
ENSMUST00000162041.1
ENSMUST00000162860.1
Gcc2


GRIP and coiled-coil domain containing 2


chr15_+_79895017 0.455 ENSMUST00000023054.7
Apobec3
apolipoprotein B mRNA editing enzyme, catalytic polypeptide 3
chr11_-_48826655 0.453 ENSMUST00000104959.1
Gm12184
predicted gene 12184
chr9_-_96631487 0.452 ENSMUST00000128346.1
ENSMUST00000034984.6
Rasa2

RAS p21 protein activator 2

chr11_+_116593687 0.450 ENSMUST00000153476.1
Aanat
arylalkylamine N-acetyltransferase
chr2_-_63184170 0.449 ENSMUST00000112452.1
Kcnh7
potassium voltage-gated channel, subfamily H (eag-related), member 7
chr2_+_79255500 0.446 ENSMUST00000099972.4
Itga4
integrin alpha 4
chr8_-_69791170 0.445 ENSMUST00000131784.1
Zfp866
zinc finger protein 866
chr19_+_28963892 0.442 ENSMUST00000045674.2
Ppapdc2
phosphatidic acid phosphatase type 2 domain containing 2
chr11_-_26210553 0.440 ENSMUST00000101447.3
5730522E02Rik
RIKEN cDNA 5730522E02 gene
chr16_-_36784924 0.436 ENSMUST00000168279.1
ENSMUST00000164579.1
ENSMUST00000023616.2
Slc15a2


solute carrier family 15 (H+/peptide transporter), member 2


chr13_-_62371936 0.429 ENSMUST00000107989.3
Gm3604
predicted gene 3604
chr6_+_34029421 0.428 ENSMUST00000070189.3
ENSMUST00000101564.2
Lrguk

leucine-rich repeats and guanylate kinase domain containing

chr19_+_44931119 0.416 ENSMUST00000096053.3
Fam178a
family with sequence similarity 178, member A
chr9_+_72958785 0.410 ENSMUST00000098567.2
ENSMUST00000034734.8
Dyx1c1

dyslexia susceptibility 1 candidate 1 homolog (human)

chr5_-_84417359 0.410 ENSMUST00000113401.1
Epha5
Eph receptor A5
chr10_-_89732253 0.409 ENSMUST00000020109.3
Actr6
ARP6 actin-related protein 6
chr7_-_83550258 0.398 ENSMUST00000177929.1
Gm10610
predicted gene 10610
chr18_-_80986578 0.398 ENSMUST00000057950.7
Sall3
sal-like 3 (Drosophila)
chr3_+_103914099 0.398 ENSMUST00000051139.6
ENSMUST00000068879.4
Rsbn1

rosbin, round spermatid basic protein 1

chr5_-_115436508 0.396 ENSMUST00000078701.3
4930430O22Rik
RIKEN cDNA 4930430O22 gene
chr2_+_3424123 0.393 ENSMUST00000061852.5
ENSMUST00000100463.3
ENSMUST00000102988.3
ENSMUST00000115066.1
Dclre1c



DNA cross-link repair 1C, PSO2 homolog (S. cerevisiae)



chr11_-_121204626 0.389 ENSMUST00000026169.6
Ogfod3
2-oxoglutarate and iron-dependent oxygenase domain containing 3
chr6_-_28397999 0.389 ENSMUST00000035930.4
Zfp800
zinc finger protein 800
chr5_+_90794530 0.387 ENSMUST00000031322.6
Cxcl15
chemokine (C-X-C motif) ligand 15
chr11_-_6475992 0.385 ENSMUST00000179343.1
Purb
purine rich element binding protein B
chr10_-_127341583 0.383 ENSMUST00000026474.3
Gli1
GLI-Kruppel family member GLI1
chr2_+_26586607 0.376 ENSMUST00000174211.1
ENSMUST00000145575.2
ENSMUST00000173920.1
Egfl7


EGF-like domain 7


chr18_+_56432116 0.373 ENSMUST00000070166.5
Gramd3
GRAM domain containing 3
chr2_+_177508570 0.369 ENSMUST00000108940.2
Gm14403
predicted gene 14403
chr14_-_65953728 0.368 ENSMUST00000042046.3
Scara3
scavenger receptor class A, member 3
chr2_-_181671622 0.368 ENSMUST00000054491.5
Sox18
SRY-box containing gene 18
chr10_-_89621253 0.367 ENSMUST00000020102.7
Slc17a8
solute carrier family 17 (sodium-dependent inorganic phosphate cotransporter), member 8
chr13_+_49653297 0.366 ENSMUST00000021824.7
Nol8
nucleolar protein 8
chr13_-_92131494 0.366 ENSMUST00000099326.3
ENSMUST00000146492.1
Rasgrf2

RAS protein-specific guanine nucleotide-releasing factor 2

chr2_-_75938407 0.365 ENSMUST00000099996.3
Ttc30b
tetratricopeptide repeat domain 30B
chr10_+_90071095 0.365 ENSMUST00000183109.1
Anks1b
ankyrin repeat and sterile alpha motif domain containing 1B
chr1_-_191318090 0.364 ENSMUST00000046770.9
Nenf
neuron derived neurotrophic factor
chr13_-_106847267 0.362 ENSMUST00000057427.4
Lrrc70
leucine rich repeat containing 70
chr17_+_21555046 0.362 ENSMUST00000079242.3
Zfp52
zinc finger protein 52
chr6_+_71282280 0.361 ENSMUST00000080949.7
Krcc1
lysine-rich coiled-coil 1
chr4_-_129378116 0.355 ENSMUST00000030610.2
Zbtb8a
zinc finger and BTB domain containing 8a
chr13_-_75943812 0.351 ENSMUST00000022078.5
ENSMUST00000109606.1
Rhobtb3

Rho-related BTB domain containing 3

chr10_+_127759721 0.351 ENSMUST00000073639.5
Rdh1
retinol dehydrogenase 1 (all trans)
chr7_+_92062392 0.349 ENSMUST00000098308.2
Dlg2
discs, large homolog 2 (Drosophila)
chr3_+_36159522 0.345 ENSMUST00000165956.2
D3Ertd254e
DNA segment, Chr 3, ERATO Doi 254, expressed
chr2_+_91257323 0.345 ENSMUST00000111349.2
ENSMUST00000131711.1
Pacsin3

protein kinase C and casein kinase substrate in neurons 3

chr12_+_36381519 0.344 ENSMUST00000062041.5
Ispd
isoprenoid synthase domain containing
chr11_+_23306884 0.343 ENSMUST00000180046.1
Usp34
ubiquitin specific peptidase 34
chr17_+_21733704 0.341 ENSMUST00000183192.1
ENSMUST00000065871.7
Zfp229

zinc finger protein 229

chr18_+_37473538 0.340 ENSMUST00000050034.1
Pcdhb15
protocadherin beta 15
chr1_-_86359455 0.338 ENSMUST00000027438.6
Ncl
nucleolin
chrX_+_75095854 0.337 ENSMUST00000033776.8
Dkc1
dyskeratosis congenita 1, dyskerin
chr4_-_99829180 0.336 ENSMUST00000146258.1
Itgb3bp
integrin beta 3 binding protein (beta3-endonexin)
chr7_-_80324115 0.336 ENSMUST00000123189.1
Rccd1
RCC1 domain containing 1
chr6_-_125236996 0.333 ENSMUST00000032486.6
Cd27
CD27 antigen
chr10_-_75798576 0.333 ENSMUST00000001713.3
Gstt1
glutathione S-transferase, theta 1
chr4_-_24851079 0.330 ENSMUST00000084781.5
ENSMUST00000108218.3
Klhl32

kelch-like 32

chr7_+_24399606 0.330 ENSMUST00000002280.4
Smg9
smg-9 homolog, nonsense mediated mRNA decay factor (C. elegans)
chr4_+_136143497 0.329 ENSMUST00000008016.2
Id3
inhibitor of DNA binding 3
chr1_-_195131536 0.327 ENSMUST00000075451.6
Cr1l
complement component (3b/4b) receptor 1-like
chr4_+_141010644 0.326 ENSMUST00000071977.8
Mfap2
microfibrillar-associated protein 2
chr13_-_104816908 0.323 ENSMUST00000022228.6
Cwc27
CWC27 spliceosome-associated protein homolog (S. cerevisiae)
chr2_+_28533355 0.322 ENSMUST00000113893.1
ENSMUST00000100241.3
Ralgds

ral guanine nucleotide dissociation stimulator

chr13_+_104817171 0.321 ENSMUST00000022230.8
Srek1ip1
splicing regulatory glutamine/lysine-rich protein 1interacting protein 1
chr8_-_25785154 0.321 ENSMUST00000038498.8
Bag4
BCL2-associated athanogene 4
chr13_+_104229366 0.320 ENSMUST00000022227.6
Cenpk
centromere protein K
chr7_-_135716374 0.317 ENSMUST00000033310.7
Mki67
antigen identified by monoclonal antibody Ki 67
chr7_-_103741322 0.317 ENSMUST00000051346.2
Olfr629
olfactory receptor 629
chr1_+_24678536 0.316 ENSMUST00000095062.3
Lmbrd1
LMBR1 domain containing 1
chr7_-_142661305 0.314 ENSMUST00000105936.1
Igf2
insulin-like growth factor 2
chr1_+_181352618 0.313 ENSMUST00000161880.1
ENSMUST00000027795.7
Cnih3

cornichon homolog 3 (Drosophila)

chr3_+_53845086 0.310 ENSMUST00000108014.1
Gm10985
predicted gene 10985
chr7_+_44896125 0.308 ENSMUST00000166552.1
ENSMUST00000168207.1
Fuz

fuzzy homolog (Drosophila)

chr3_-_146781351 0.306 ENSMUST00000005164.7
Prkacb
protein kinase, cAMP dependent, catalytic, beta
chr2_+_150909565 0.306 ENSMUST00000028948.4
Gins1
GINS complex subunit 1 (Psf1 homolog)
chr7_+_19359740 0.297 ENSMUST00000140836.1
Ppp1r13l
protein phosphatase 1, regulatory (inhibitor) subunit 13 like
chr18_+_37484955 0.297 ENSMUST00000053856.4
Pcdhb17
protocadherin beta 17
chr14_-_45477856 0.294 ENSMUST00000141424.1
Fermt2
fermitin family homolog 2 (Drosophila)
chr4_+_98546710 0.291 ENSMUST00000102792.3
Inadl
InaD-like (Drosophila)
chr2_-_114654943 0.289 ENSMUST00000028640.7
ENSMUST00000102542.3
Dph6

diphthamine biosynthesis 6

chr18_-_10610346 0.289 ENSMUST00000025142.5
Esco1
establishment of cohesion 1 homolog 1 (S. cerevisiae)
chr11_+_23306910 0.289 ENSMUST00000137823.1
Usp34
ubiquitin specific peptidase 34
chr16_+_96205719 0.288 ENSMUST00000129904.1
Sh3bgr
SH3-binding domain glutamic acid-rich protein
chr9_+_96258697 0.287 ENSMUST00000179416.1
Tfdp2
transcription factor Dp 2
chrM_+_2743 0.286 ENSMUST00000082392.1
mt-Nd1
mitochondrially encoded NADH dehydrogenase 1
chr12_-_20900867 0.286 ENSMUST00000079237.5
Zfp125
zinc finger protein 125
chr19_+_5425121 0.285 ENSMUST00000159759.1
AI837181
expressed sequence AI837181
chr5_-_143180721 0.284 ENSMUST00000164068.1
ENSMUST00000049861.4
ENSMUST00000165318.1
Rbak


RB-associated KRAB repressor


chr1_+_58646608 0.284 ENSMUST00000081455.4
Gm10068
predicted gene 10068
chr8_-_26119125 0.283 ENSMUST00000037182.7
Hook3
hook homolog 3 (Drosophila)
chr18_+_61105561 0.281 ENSMUST00000025523.6
Csf1r
colony stimulating factor 1 receptor
chrX_+_13466110 0.281 ENSMUST00000050434.5
Nyx
nyctalopin
chr10_+_75037066 0.281 ENSMUST00000147802.1
ENSMUST00000020391.5
Rab36

RAB36, member RAS oncogene family

chrX_+_129749740 0.279 ENSMUST00000167619.2
ENSMUST00000037854.8
Diap2

diaphanous homolog 2 (Drosophila)

chr2_-_155592567 0.278 ENSMUST00000155347.1
ENSMUST00000130881.1
ENSMUST00000079691.6
Gss


glutathione synthetase


chr11_+_100415697 0.277 ENSMUST00000001595.3
Fkbp10
FK506 binding protein 10
chr7_+_45526330 0.277 ENSMUST00000120985.1
ENSMUST00000051810.8
Plekha4

pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 4

chr3_-_121171678 0.275 ENSMUST00000170781.1
ENSMUST00000039761.5
ENSMUST00000106467.1
ENSMUST00000106466.3
ENSMUST00000164925.2
Rwdd3




RWD domain containing 3




chr11_-_69900886 0.274 ENSMUST00000108621.2
ENSMUST00000100969.2
2810408A11Rik

RIKEN cDNA 2810408A11 gene

chr17_-_25792284 0.272 ENSMUST00000072735.7
Fam173a
family with sequence similarity 173, member A
chr10_-_62880014 0.271 ENSMUST00000050826.7
Tet1
tet methylcytosine dioxygenase 1
chr18_+_37341702 0.271 ENSMUST00000053037.3
Pcdhb7
protocadherin beta 7
chr11_-_29515017 0.269 ENSMUST00000133103.1
ENSMUST00000039900.3
Prorsd1

prolyl-tRNA synthetase domain containing 1

chrX_+_159708593 0.265 ENSMUST00000080394.6
Sh3kbp1
SH3-domain kinase binding protein 1
chr1_-_33814591 0.265 ENSMUST00000019861.6
Zfp451
zinc finger protein 451
chr13_+_75839868 0.263 ENSMUST00000022082.7
Glrx
glutaredoxin
chr6_+_136954521 0.262 ENSMUST00000137768.1
Pde6h
phosphodiesterase 6H, cGMP-specific, cone, gamma
chr5_+_76588663 0.261 ENSMUST00000121979.1
Cep135
centrosomal protein 135
chr5_-_130002838 0.258 ENSMUST00000111308.1
ENSMUST00000111307.1
Gusb

glucuronidase, beta

chr8_-_126971062 0.257 ENSMUST00000045994.6
Rbm34
RNA binding motif protein 34
chr9_-_31464238 0.256 ENSMUST00000048050.7
Tmem45b
transmembrane protein 45b
chrM_+_7759 0.255 ENSMUST00000082407.1
ENSMUST00000082408.1
mt-Atp8
mt-Atp6
mitochondrially encoded ATP synthase 8
mitochondrially encoded ATP synthase 6
chr11_+_70764209 0.255 ENSMUST00000060444.5
Zfp3
zinc finger protein 3
chr7_+_141291988 0.254 ENSMUST00000026569.4
Drd4
dopamine receptor D4
chr19_-_29812952 0.252 ENSMUST00000099525.3
Ranbp6
RAN binding protein 6
chr16_+_64851991 0.251 ENSMUST00000067744.7
Cggbp1
CGG triplet repeat binding protein 1
chr9_-_60838200 0.251 ENSMUST00000063858.7
Gm9869
predicted gene 9869
chr17_+_43667389 0.251 ENSMUST00000170988.1
Cyp39a1
cytochrome P450, family 39, subfamily a, polypeptide 1
chr7_-_123369870 0.249 ENSMUST00000106442.2
ENSMUST00000098060.3
ENSMUST00000167309.1
Arhgap17


Rho GTPase activating protein 17


chrY_+_90755657 0.249 ENSMUST00000167967.2
Gm21857
predicted gene, 21857
chr2_+_52038005 0.243 ENSMUST00000065927.5
Tnfaip6
tumor necrosis factor alpha induced protein 6
chr18_+_37435602 0.243 ENSMUST00000055495.5
Pcdhb12
protocadherin beta 12
chr12_+_111039334 0.242 ENSMUST00000084968.7
Rcor1
REST corepressor 1
chr1_+_171840607 0.242 ENSMUST00000136479.1
ENSMUST00000042302.6
Cd84

CD84 antigen

chr3_-_46447939 0.241 ENSMUST00000166505.1
Pabpc4l
poly(A) binding protein, cytoplasmic 4-like
chr17_+_78937124 0.241 ENSMUST00000024887.4
Ndufaf7
NADH dehydrogenase (ubiquinone) 1 alpha subcomplex assembly factor 7

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
1.1 6.9 GO:0003350 pulmonary myocardium development(GO:0003350)
0.4 1.1 GO:0019343 cysteine biosynthetic process via cystathionine(GO:0019343) cysteine biosynthetic process(GO:0019344)
0.3 2.0 GO:0044838 cell quiescence(GO:0044838)
0.2 0.7 GO:1904956 regulation of midbrain dopaminergic neuron differentiation(GO:1904956) regulation of planar cell polarity pathway involved in axis elongation(GO:2000040) negative regulation of planar cell polarity pathway involved in axis elongation(GO:2000041)
0.2 1.2 GO:0070459 prolactin secretion(GO:0070459)
0.2 0.2 GO:0001541 ovarian follicle development(GO:0001541)
0.2 1.6 GO:0070494 regulation of thrombin receptor signaling pathway(GO:0070494) negative regulation of thrombin receptor signaling pathway(GO:0070495)
0.2 0.6 GO:1901079 positive regulation of phospholipase C-activating G-protein coupled receptor signaling pathway(GO:1900738) positive regulation of relaxation of muscle(GO:1901079)
0.2 0.7 GO:0051599 response to hydrostatic pressure(GO:0051599)
0.1 0.4 GO:2000314 negative regulation of fibroblast growth factor receptor signaling pathway involved in neural plate anterior/posterior pattern formation(GO:2000314)
0.1 0.4 GO:2000616 negative regulation of histone H3-K9 acetylation(GO:2000616)
0.1 0.7 GO:0098735 positive regulation of the force of heart contraction(GO:0098735)
0.1 0.6 GO:0021856 cerebral cortex tangential migration using cell-axon interactions(GO:0021824) gonadotrophin-releasing hormone neuronal migration to the hypothalamus(GO:0021828) hypothalamic tangential migration using cell-axon interactions(GO:0021856) dichotomous subdivision of terminal units involved in salivary gland branching(GO:0060666) facioacoustic ganglion development(GO:1903375)
0.1 0.4 GO:0048866 stem cell fate specification(GO:0048866)
0.1 4.9 GO:0032728 positive regulation of interferon-beta production(GO:0032728)
0.1 0.6 GO:0070327 thyroid hormone transport(GO:0070327)
0.1 0.2 GO:0021508 floor plate formation(GO:0021508) floor plate morphogenesis(GO:0033505)
0.1 0.3 GO:0043181 vacuolar sequestering(GO:0043181)
0.1 0.4 GO:1904996 diapedesis(GO:0050904) positive regulation of leukocyte adhesion to vascular endothelial cell(GO:1904996)
0.1 0.3 GO:0042196 dichloromethane metabolic process(GO:0018900) chlorinated hydrocarbon metabolic process(GO:0042196) halogenated hydrocarbon metabolic process(GO:0042197)
0.1 1.5 GO:0001886 endothelial cell morphogenesis(GO:0001886)
0.1 0.4 GO:0060032 notochord regression(GO:0060032)
0.1 0.3 GO:1902071 positive regulation of cellular response to hypoxia(GO:1900039) regulation of hypoxia-inducible factor-1alpha signaling pathway(GO:1902071)
0.1 0.3 GO:0090310 negative regulation of methylation-dependent chromatin silencing(GO:0090310)
0.1 0.4 GO:0042891 antibiotic transport(GO:0042891) dipeptide transport(GO:0042938)
0.1 0.2 GO:0046947 hydroxylysine metabolic process(GO:0046946) hydroxylysine biosynthetic process(GO:0046947)
0.1 0.7 GO:0006390 transcription from mitochondrial promoter(GO:0006390)
0.1 0.2 GO:2001180 regulation of interleukin-18 production(GO:0032661) negative regulation of interleukin-18 production(GO:0032701) negative regulation of interleukin-10 secretion(GO:2001180)
0.1 0.3 GO:0090365 regulation of mRNA modification(GO:0090365)
0.1 0.5 GO:0031120 snRNA pseudouridine synthesis(GO:0031120)
0.1 0.2 GO:0071879 positive regulation of adrenergic receptor signaling pathway(GO:0071879) negative regulation of locomotion involved in locomotory behavior(GO:0090327)
0.1 0.5 GO:0032196 regulation of transposition(GO:0010528) negative regulation of transposition(GO:0010529) transposition(GO:0032196)
0.1 0.3 GO:0038145 macrophage colony-stimulating factor signaling pathway(GO:0038145)
0.1 0.2 GO:0032058 positive regulation of translational initiation in response to stress(GO:0032058)
0.1 0.4 GO:0090074 negative regulation of protein homodimerization activity(GO:0090074)
0.1 0.3 GO:2000587 negative regulation of platelet-derived growth factor receptor-beta signaling pathway(GO:2000587)
0.1 0.6 GO:0035095 behavioral response to nicotine(GO:0035095)
0.1 0.3 GO:0032417 positive regulation of sodium:proton antiporter activity(GO:0032417)
0.1 0.2 GO:0036092 phosphatidylinositol-3-phosphate biosynthetic process(GO:0036092)
0.1 0.2 GO:0003219 atrioventricular node development(GO:0003162) cardiac right ventricle formation(GO:0003219)
0.1 0.2 GO:2000562 negative regulation of CD4-positive, alpha-beta T cell proliferation(GO:2000562)
0.1 0.3 GO:0034421 post-translational protein acetylation(GO:0034421)
0.1 0.3 GO:0071955 recycling endosome to Golgi transport(GO:0071955)
0.1 0.2 GO:0071707 immunoglobulin heavy chain V-D-J recombination(GO:0071707)
0.1 0.4 GO:0045002 double-strand break repair via single-strand annealing(GO:0045002)
0.1 0.3 GO:0045078 positive regulation of interferon-gamma biosynthetic process(GO:0045078)
0.1 0.2 GO:0001920 negative regulation of receptor recycling(GO:0001920)
0.1 0.4 GO:0071372 cellular response to follicle-stimulating hormone stimulus(GO:0071372)
0.1 0.4 GO:2000232 regulation of rRNA processing(GO:2000232)
0.1 0.2 GO:0044028 DNA hypomethylation(GO:0044028) hypomethylation of CpG island(GO:0044029)
0.0 0.4 GO:0042435 indole-containing compound biosynthetic process(GO:0042435)
0.0 0.7 GO:0006309 apoptotic DNA fragmentation(GO:0006309)
0.0 0.4 GO:0031848 protection from non-homologous end joining at telomere(GO:0031848)
0.0 0.2 GO:0045654 positive regulation of megakaryocyte differentiation(GO:0045654)
0.0 0.8 GO:0060134 prepulse inhibition(GO:0060134)
0.0 0.1 GO:0070427 nucleotide-binding oligomerization domain containing 1 signaling pathway(GO:0070427)
0.0 0.2 GO:1902309 negative regulation of peptidyl-serine dephosphorylation(GO:1902309)
0.0 0.2 GO:0006663 platelet activating factor biosynthetic process(GO:0006663)
0.0 0.3 GO:0038028 insulin receptor signaling pathway via phosphatidylinositol 3-kinase(GO:0038028)
0.0 0.4 GO:0032096 negative regulation of response to food(GO:0032096) negative regulation of appetite(GO:0032099)
0.0 1.4 GO:0009409 response to cold(GO:0009409)
0.0 0.7 GO:0016322 neuron remodeling(GO:0016322)
0.0 0.2 GO:1902683 regulation of receptor localization to synapse(GO:1902683)
0.0 0.3 GO:0006621 protein retention in ER lumen(GO:0006621)
0.0 0.3 GO:2000258 negative regulation of complement activation(GO:0045916) negative regulation of protein activation cascade(GO:2000258)
0.0 0.3 GO:0034454 microtubule anchoring at centrosome(GO:0034454)
0.0 0.2 GO:0034080 CENP-A containing nucleosome assembly(GO:0034080) CENP-A containing chromatin organization(GO:0061641)
0.0 0.2 GO:0006547 histidine metabolic process(GO:0006547) imidazole-containing compound catabolic process(GO:0052805)
0.0 0.2 GO:0035247 peptidyl-arginine omega-N-methylation(GO:0035247)
0.0 1.9 GO:0046676 negative regulation of insulin secretion(GO:0046676)
0.0 0.2 GO:0032229 positive regulation of gamma-aminobutyric acid secretion(GO:0014054) negative regulation of synaptic transmission, GABAergic(GO:0032229)
0.0 0.3 GO:0035269 protein O-linked mannosylation(GO:0035269)
0.0 0.1 GO:0051105 regulation of DNA ligation(GO:0051105) positive regulation of DNA ligation(GO:0051106)
0.0 0.2 GO:0009449 gamma-aminobutyric acid biosynthetic process(GO:0009449)
0.0 0.4 GO:0036158 outer dynein arm assembly(GO:0036158)
0.0 0.1 GO:0009814 defense response, incompatible interaction(GO:0009814)
0.0 0.4 GO:1902570 protein localization to nucleolus(GO:1902570)
0.0 0.1 GO:0008594 photoreceptor cell morphogenesis(GO:0008594)
0.0 0.2 GO:0051790 short-chain fatty acid biosynthetic process(GO:0051790)
0.0 0.0 GO:0010890 positive regulation of sequestering of triglyceride(GO:0010890)
0.0 0.7 GO:0002495 antigen processing and presentation of peptide antigen via MHC class II(GO:0002495)
0.0 0.2 GO:1900095 regulation of dosage compensation by inactivation of X chromosome(GO:1900095)
0.0 0.6 GO:0048240 sperm capacitation(GO:0048240)
0.0 0.2 GO:0050716 positive regulation of interleukin-1 secretion(GO:0050716) positive regulation of interleukin-1 beta secretion(GO:0050718)
0.0 0.2 GO:0002002 regulation of angiotensin levels in blood(GO:0002002)
0.0 0.1 GO:1902626 assembly of large subunit precursor of preribosome(GO:1902626)
0.0 0.3 GO:1901621 negative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning(GO:1901621)
0.0 0.9 GO:0034113 heterotypic cell-cell adhesion(GO:0034113)
0.0 0.4 GO:1900383 regulation of synaptic plasticity by receptor localization to synapse(GO:1900383)
0.0 0.5 GO:2000310 regulation of N-methyl-D-aspartate selective glutamate receptor activity(GO:2000310)
0.0 0.4 GO:0010818 T cell chemotaxis(GO:0010818)
0.0 0.1 GO:0046368 GDP-L-fucose metabolic process(GO:0046368)
0.0 0.3 GO:1902969 mitotic DNA replication(GO:1902969)
0.0 0.1 GO:0043031 negative regulation of macrophage activation(GO:0043031)
0.0 0.3 GO:0000729 DNA double-strand break processing(GO:0000729)
0.0 0.6 GO:0006044 N-acetylglucosamine metabolic process(GO:0006044)
0.0 0.2 GO:0046477 glycosylceramide catabolic process(GO:0046477)
0.0 0.7 GO:0071108 protein K48-linked deubiquitination(GO:0071108)
0.0 0.1 GO:1905034 regulation of antifungal innate immune response(GO:1905034) negative regulation of antifungal innate immune response(GO:1905035)
0.0 0.1 GO:0061756 cellular extravasation(GO:0045123) leukocyte tethering or rolling(GO:0050901) leukocyte adhesion to vascular endothelial cell(GO:0061756)
0.0 0.2 GO:2000807 regulation of synaptic vesicle clustering(GO:2000807)
0.0 0.1 GO:0002949 tRNA threonylcarbamoyladenosine modification(GO:0002949)
0.0 0.1 GO:1990481 mRNA pseudouridine synthesis(GO:1990481)
0.0 0.1 GO:0036482 neuron intrinsic apoptotic signaling pathway in response to hydrogen peroxide(GO:0036482) positive regulation of mitochondrial electron transport, NADH to ubiquinone(GO:1902958) regulation of hydrogen peroxide-induced neuron intrinsic apoptotic signaling pathway(GO:1903383) negative regulation of hydrogen peroxide-induced neuron intrinsic apoptotic signaling pathway(GO:1903384)
0.0 0.1 GO:0044375 regulation of peroxisome size(GO:0044375)
0.0 0.5 GO:0043968 histone H2A acetylation(GO:0043968)
0.0 3.2 GO:0007416 synapse assembly(GO:0007416)
0.0 0.1 GO:2000642 negative regulation of early endosome to late endosome transport(GO:2000642)
0.0 0.1 GO:1903070 negative regulation of ER-associated ubiquitin-dependent protein catabolic process(GO:1903070)
0.0 0.1 GO:0010636 positive regulation of mitochondrial fusion(GO:0010636)
0.0 0.3 GO:0010457 centriole-centriole cohesion(GO:0010457)
0.0 1.0 GO:0045744 negative regulation of G-protein coupled receptor protein signaling pathway(GO:0045744)
0.0 0.1 GO:0051661 maintenance of centrosome location(GO:0051661)
0.0 0.6 GO:0000413 protein peptidyl-prolyl isomerization(GO:0000413)
0.0 0.3 GO:0006750 glutathione biosynthetic process(GO:0006750)
0.0 2.6 GO:0006413 translational initiation(GO:0006413)
0.0 0.8 GO:0035640 exploration behavior(GO:0035640)
0.0 0.3 GO:0045745 positive regulation of G-protein coupled receptor protein signaling pathway(GO:0045745)
0.0 0.3 GO:2000311 regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity(GO:2000311)
0.0 0.1 GO:0038018 Wnt receptor catabolic process(GO:0038018)
0.0 0.1 GO:0007320 insemination(GO:0007320)
0.0 0.2 GO:0016246 RNA interference(GO:0016246)
0.0 0.2 GO:0046085 adenosine metabolic process(GO:0046085)
0.0 0.4 GO:0036344 platelet morphogenesis(GO:0036344)
0.0 0.2 GO:0045624 positive regulation of T-helper cell differentiation(GO:0045624) positive regulation of histone H3-K9 methylation(GO:0051574)
0.0 0.2 GO:0008272 sulfate transport(GO:0008272)
0.0 0.1 GO:0019673 GDP-mannose metabolic process(GO:0019673)
0.0 0.3 GO:0051044 positive regulation of membrane protein ectodomain proteolysis(GO:0051044)
0.0 0.2 GO:0006610 ribosomal protein import into nucleus(GO:0006610)
0.0 0.2 GO:0021891 olfactory bulb interneuron development(GO:0021891)
0.0 0.3 GO:0097120 receptor localization to synapse(GO:0097120)
0.0 0.2 GO:0055090 acylglycerol homeostasis(GO:0055090) triglyceride homeostasis(GO:0070328)
0.0 0.3 GO:0003215 cardiac right ventricle morphogenesis(GO:0003215)
0.0 0.2 GO:0016127 cholesterol catabolic process(GO:0006707) sterol catabolic process(GO:0016127)
0.0 0.7 GO:0090162 establishment of epithelial cell polarity(GO:0090162)
0.0 0.1 GO:0016584 nucleosome positioning(GO:0016584)
0.0 0.1 GO:0002175 protein localization to paranode region of axon(GO:0002175)
0.0 0.4 GO:0031571 mitotic G1 DNA damage checkpoint(GO:0031571)
0.0 0.1 GO:0046602 regulation of mitotic centrosome separation(GO:0046602)
0.0 0.0 GO:1990705 cholangiocyte proliferation(GO:1990705)
0.0 0.3 GO:0009083 branched-chain amino acid catabolic process(GO:0009083)
0.0 0.2 GO:0032757 positive regulation of interleukin-8 production(GO:0032757)
0.0 0.1 GO:0061092 regulation of phospholipid translocation(GO:0061091) positive regulation of phospholipid translocation(GO:0061092)
0.0 0.3 GO:0030903 notochord development(GO:0030903)
0.0 0.2 GO:1901550 regulation of endothelial cell development(GO:1901550) regulation of establishment of endothelial barrier(GO:1903140)
0.0 0.2 GO:0045836 positive regulation of meiotic nuclear division(GO:0045836)
0.0 0.2 GO:0050860 negative regulation of T cell receptor signaling pathway(GO:0050860)
0.0 0.5 GO:0042246 tissue regeneration(GO:0042246)
0.0 0.1 GO:0050908 detection of light stimulus involved in visual perception(GO:0050908) detection of light stimulus involved in sensory perception(GO:0050962)
0.0 0.1 GO:0045583 regulation of cytotoxic T cell differentiation(GO:0045583) positive regulation of cytotoxic T cell differentiation(GO:0045585)
0.0 0.3 GO:0099517 anterograde synaptic vesicle transport(GO:0048490) synaptic vesicle cytoskeletal transport(GO:0099514) synaptic vesicle transport along microtubule(GO:0099517)
0.0 0.1 GO:0035845 photoreceptor cell outer segment organization(GO:0035845)
0.0 0.2 GO:0043045 DNA methylation involved in embryo development(GO:0043045) changes to DNA methylation involved in embryo development(GO:1901538)
0.0 0.4 GO:0001523 retinoid metabolic process(GO:0001523)
0.0 0.1 GO:0016540 protein autoprocessing(GO:0016540)
0.0 0.1 GO:0048318 axial mesoderm development(GO:0048318)
0.0 0.0 GO:0000733 DNA strand renaturation(GO:0000733)
0.0 0.3 GO:0007608 sensory perception of smell(GO:0007608)
0.0 0.3 GO:0033622 integrin activation(GO:0033622)
0.0 0.8 GO:0061077 chaperone-mediated protein folding(GO:0061077)
0.0 0.3 GO:0040015 negative regulation of multicellular organism growth(GO:0040015)
0.0 0.5 GO:0042073 intraciliary transport(GO:0042073)
0.0 0.0 GO:0046501 protoporphyrinogen IX metabolic process(GO:0046501)
0.0 0.2 GO:0010758 regulation of macrophage chemotaxis(GO:0010758)
0.0 0.2 GO:0051898 negative regulation of protein kinase B signaling(GO:0051898)
0.0 0.2 GO:0006953 acute-phase response(GO:0006953)
0.0 0.6 GO:0048260 positive regulation of receptor-mediated endocytosis(GO:0048260)
0.0 0.4 GO:0045746 negative regulation of Notch signaling pathway(GO:0045746)
0.0 0.1 GO:0000244 spliceosomal tri-snRNP complex assembly(GO:0000244)
0.0 0.1 GO:0002544 chronic inflammatory response(GO:0002544)
0.0 0.0 GO:0000237 leptotene(GO:0000237) negative regulation of t-circle formation(GO:1904430)
0.0 0.1 GO:0034983 peptidyl-lysine deacetylation(GO:0034983)
0.0 0.1 GO:0007042 lysosomal lumen acidification(GO:0007042)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.2 GO:0097487 vesicle lumen(GO:0031983) multivesicular body, internal vesicle(GO:0097487)
0.3 0.9 GO:0005927 muscle tendon junction(GO:0005927)
0.1 0.6 GO:0031092 platelet alpha granule membrane(GO:0031092)
0.1 0.5 GO:0008282 ATP-sensitive potassium channel complex(GO:0008282)
0.1 0.6 GO:0071556 integral component of cytoplasmic side of endoplasmic reticulum membrane(GO:0071458) integral component of lumenal side of endoplasmic reticulum membrane(GO:0071556) lumenal side of endoplasmic reticulum membrane(GO:0098553)
0.1 0.6 GO:0032777 Piccolo NuA4 histone acetyltransferase complex(GO:0032777)
0.1 0.4 GO:0071006 U2-type catalytic step 1 spliceosome(GO:0071006)
0.1 0.3 GO:0000811 GINS complex(GO:0000811)
0.1 0.3 GO:1990682 CSF1-CSF1R complex(GO:1990682)
0.1 1.4 GO:0043083 synaptic cleft(GO:0043083)
0.1 0.4 GO:0097450 astrocyte end-foot(GO:0097450)
0.1 0.9 GO:0030285 integral component of synaptic vesicle membrane(GO:0030285) intrinsic component of synaptic vesicle membrane(GO:0098563)
0.1 0.3 GO:0001651 dense fibrillar component(GO:0001651)
0.1 0.3 GO:0090661 box H/ACA telomerase RNP complex(GO:0090661)
0.1 0.1 GO:0072588 box H/ACA snoRNP complex(GO:0031429) box H/ACA RNP complex(GO:0072588)
0.1 0.2 GO:0034272 phosphatidylinositol 3-kinase complex, class III, type I(GO:0034271) phosphatidylinositol 3-kinase complex, class III, type II(GO:0034272)
0.1 1.3 GO:0016581 NuRD complex(GO:0016581) CHD-type complex(GO:0090545)
0.1 0.6 GO:0005892 acetylcholine-gated channel complex(GO:0005892)
0.1 0.2 GO:0005943 phosphatidylinositol 3-kinase complex, class IA(GO:0005943)
0.0 0.2 GO:0071008 U2-type post-mRNA release spliceosomal complex(GO:0071008)
0.0 0.3 GO:0070695 FHF complex(GO:0070695)
0.0 0.5 GO:0097542 ciliary tip(GO:0097542)
0.0 0.9 GO:0005666 DNA-directed RNA polymerase III complex(GO:0005666)
0.0 0.4 GO:0005581 collagen trimer(GO:0005581)
0.0 0.2 GO:0002193 MAML1-RBP-Jkappa- ICN1 complex(GO:0002193)
0.0 0.4 GO:0070419 nonhomologous end joining complex(GO:0070419)
0.0 0.1 GO:1902636 kinociliary basal body(GO:1902636)
0.0 1.0 GO:0044306 neuron projection terminus(GO:0044306)
0.0 0.1 GO:0034274 Atg12-Atg5-Atg16 complex(GO:0034274)
0.0 0.2 GO:0031021 interphase microtubule organizing center(GO:0031021)
0.0 2.6 GO:0001669 acrosomal vesicle(GO:0001669)
0.0 0.2 GO:0034098 VCP-NPL4-UFD1 AAA ATPase complex(GO:0034098)
0.0 0.4 GO:0005662 DNA replication factor A complex(GO:0005662)
0.0 0.7 GO:0030992 intraciliary transport particle B(GO:0030992)
0.0 0.4 GO:1990635 proximal dendrite(GO:1990635)
0.0 0.1 GO:0042583 chromaffin granule(GO:0042583)
0.0 0.3 GO:0005665 DNA-directed RNA polymerase II, core complex(GO:0005665)
0.0 0.3 GO:0005952 cAMP-dependent protein kinase complex(GO:0005952)
0.0 0.3 GO:0043205 microfibril(GO:0001527) fibril(GO:0043205)
0.0 1.5 GO:0000307 cyclin-dependent protein kinase holoenzyme complex(GO:0000307)
0.0 0.4 GO:0008305 integrin complex(GO:0008305) protein complex involved in cell adhesion(GO:0098636)
0.0 0.1 GO:0036449 microtubule minus-end(GO:0036449)
0.0 0.1 GO:0000408 EKC/KEOPS complex(GO:0000408)
0.0 0.7 GO:0032588 trans-Golgi network membrane(GO:0032588)
0.0 0.3 GO:0005903 brush border(GO:0005903)
0.0 0.1 GO:0000931 gamma-tubulin large complex(GO:0000931) gamma-tubulin ring complex(GO:0008274)
0.0 0.3 GO:0000276 mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276)
0.0 0.1 GO:0031314 extrinsic component of mitochondrial inner membrane(GO:0031314)
0.0 0.1 GO:0097454 Schwann cell microvillus(GO:0097454)
0.0 0.1 GO:0000220 vacuolar proton-transporting V-type ATPase, V0 domain(GO:0000220)
0.0 0.2 GO:0030130 clathrin coat of trans-Golgi network vesicle(GO:0030130)
0.0 0.2 GO:0034361 very-low-density lipoprotein particle(GO:0034361) triglyceride-rich lipoprotein particle(GO:0034385)
0.0 0.2 GO:0030057 desmosome(GO:0030057)
0.0 0.2 GO:0097539 ciliary transition fiber(GO:0097539)
0.0 1.0 GO:0009925 basal plasma membrane(GO:0009925)
0.0 0.1 GO:0030991 intraciliary transport particle A(GO:0030991)
0.0 0.1 GO:0005736 DNA-directed RNA polymerase I complex(GO:0005736)
0.0 0.2 GO:0030123 AP-3 adaptor complex(GO:0030123)
0.0 1.1 GO:0005578 proteinaceous extracellular matrix(GO:0005578)
0.0 0.3 GO:0031941 filamentous actin(GO:0031941)
0.0 0.2 GO:0031011 Ino80 complex(GO:0031011)
0.0 0.1 GO:0098536 deuterosome(GO:0098536)
0.0 0.2 GO:0000346 transcription export complex(GO:0000346)
0.0 0.1 GO:0000164 protein phosphatase type 1 complex(GO:0000164)
0.0 0.1 GO:1990130 Iml1 complex(GO:1990130)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 7.5 GO:0038191 neuropilin binding(GO:0038191)
0.5 1.5 GO:0098770 FBXO family protein binding(GO:0098770)
0.4 1.2 GO:0005006 epidermal growth factor-activated receptor activity(GO:0005006)
0.3 1.0 GO:0098809 nitrite reductase activity(GO:0098809)
0.3 1.0 GO:0005008 hepatocyte growth factor-activated receptor activity(GO:0005008)
0.2 0.7 GO:0004531 deoxyribonuclease II activity(GO:0004531)
0.2 0.7 GO:0048763 calcium-induced calcium release activity(GO:0048763)
0.2 0.5 GO:0015272 ATP-activated inward rectifier potassium channel activity(GO:0015272)
0.2 0.7 GO:0086038 calcium:sodium antiporter activity involved in regulation of cardiac muscle cell membrane potential(GO:0086038)
0.2 0.7 GO:0000179 rRNA (adenine-N6,N6-)-dimethyltransferase activity(GO:0000179)
0.1 0.6 GO:0015349 thyroid hormone transmembrane transporter activity(GO:0015349)
0.1 0.4 GO:0042936 dipeptide transporter activity(GO:0042936)
0.1 1.9 GO:0016641 oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor(GO:0016641)
0.1 0.3 GO:0004574 oligo-1,6-glucosidase activity(GO:0004574)
0.1 0.5 GO:0047844 deoxycytidine deaminase activity(GO:0047844)
0.1 0.6 GO:0004342 glucosamine-6-phosphate deaminase activity(GO:0004342)
0.1 0.3 GO:0019120 hydrolase activity, acting on acid halide bonds(GO:0016824) hydrolase activity, acting on acid halide bonds, in C-halide compounds(GO:0019120) alkylhalidase activity(GO:0047651)
0.1 0.4 GO:0032422 purine-rich negative regulatory element binding(GO:0032422)
0.1 0.6 GO:0050544 arachidonic acid binding(GO:0050544)
0.1 0.4 GO:0019960 C-X3-C chemokine binding(GO:0019960)
0.1 0.3 GO:0015038 glutathione disulfide oxidoreductase activity(GO:0015038) protein-disulfide reductase (glutathione) activity(GO:0019153)
0.1 0.3 GO:0001591 dopamine neurotransmitter receptor activity, coupled via Gi/Go(GO:0001591)
0.1 0.3 GO:0008534 oxidized purine nucleobase lesion DNA N-glycosylase activity(GO:0008534)
0.1 0.3 GO:0070051 fibrinogen binding(GO:0070051)
0.1 0.2 GO:0005332 gamma-aminobutyric acid:sodium symporter activity(GO:0005332)
0.1 0.4 GO:0048248 CXCR3 chemokine receptor binding(GO:0048248)
0.1 0.3 GO:0046923 ER retention sequence binding(GO:0046923)
0.1 0.5 GO:0034513 box H/ACA snoRNA binding(GO:0034513)
0.1 0.3 GO:0042134 rRNA primary transcript binding(GO:0042134)
0.1 0.4 GO:0061665 SUMO ligase activity(GO:0061665)
0.1 0.2 GO:0035243 protein-arginine omega-N symmetric methyltransferase activity(GO:0035243)
0.1 1.0 GO:0005242 inward rectifier potassium channel activity(GO:0005242)
0.1 0.6 GO:0022848 acetylcholine-gated cation channel activity(GO:0022848)
0.1 0.2 GO:0071987 WD40-repeat domain binding(GO:0071987)
0.1 0.2 GO:0004315 3-oxoacyl-[acyl-carrier-protein] synthase activity(GO:0004315)
0.1 0.2 GO:0016509 long-chain-3-hydroxyacyl-CoA dehydrogenase activity(GO:0016509)
0.1 0.3 GO:0004984 olfactory receptor activity(GO:0004984)
0.1 1.0 GO:0005528 macrolide binding(GO:0005527) FK506 binding(GO:0005528)
0.1 0.4 GO:0005004 GPI-linked ephrin receptor activity(GO:0005004)
0.0 0.1 GO:0043120 tumor necrosis factor binding(GO:0043120)
0.0 0.3 GO:0070579 methylcytosine dioxygenase activity(GO:0070579)
0.0 0.3 GO:0031419 cobalamin binding(GO:0031419)
0.0 0.1 GO:0035402 histone kinase activity (H3-T11 specific)(GO:0035402)
0.0 0.2 GO:0008269 JAK pathway signal transduction adaptor activity(GO:0008269)
0.0 0.2 GO:0008475 procollagen-lysine 5-dioxygenase activity(GO:0008475)
0.0 0.2 GO:0016812 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides(GO:0016812)
0.0 0.6 GO:0000014 single-stranded DNA endodeoxyribonuclease activity(GO:0000014)
0.0 0.2 GO:0004142 diacylglycerol cholinephosphotransferase activity(GO:0004142)
0.0 0.2 GO:0016841 ammonia-lyase activity(GO:0016841)
0.0 0.1 GO:0061711 N(6)-L-threonylcarbamoyladenine synthase(GO:0061711)
0.0 0.2 GO:0004351 glutamate decarboxylase activity(GO:0004351)
0.0 0.1 GO:0008310 single-stranded DNA 3'-5' exodeoxyribonuclease activity(GO:0008310)
0.0 1.6 GO:0005547 phosphatidylinositol-3,4,5-trisphosphate binding(GO:0005547)
0.0 0.3 GO:0008395 steroid hydroxylase activity(GO:0008395)
0.0 0.1 GO:0019776 Atg8 ligase activity(GO:0019776)
0.0 0.3 GO:0004691 cAMP-dependent protein kinase activity(GO:0004691)
0.0 0.9 GO:0043236 laminin binding(GO:0043236)
0.0 0.4 GO:0005078 MAP-kinase scaffold activity(GO:0005078)
0.0 0.3 GO:0019855 calcium channel inhibitor activity(GO:0019855)
0.0 0.7 GO:0042287 MHC protein binding(GO:0042287)
0.0 0.4 GO:0031418 L-ascorbic acid binding(GO:0031418)
0.0 0.1 GO:0004719 protein-L-isoaspartate (D-aspartate) O-methyltransferase activity(GO:0004719)
0.0 0.3 GO:0004300 enoyl-CoA hydratase activity(GO:0004300)
0.0 0.2 GO:0032050 clathrin heavy chain binding(GO:0032050)
0.0 0.2 GO:0004614 phosphoglucomutase activity(GO:0004614)
0.0 0.1 GO:0003810 protein-glutamine gamma-glutamyltransferase activity(GO:0003810)
0.0 0.3 GO:0004745 retinol dehydrogenase activity(GO:0004745)
0.0 5.0 GO:0001078 transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078)
0.0 0.5 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.0 0.1 GO:0004427 inorganic diphosphatase activity(GO:0004427)
0.0 0.3 GO:0035004 1-phosphatidylinositol-3-kinase activity(GO:0016303) phosphatidylinositol 3-kinase activity(GO:0035004)
0.0 0.8 GO:0005504 fatty acid binding(GO:0005504)
0.0 0.2 GO:0019531 secondary active sulfate transmembrane transporter activity(GO:0008271) oxalate transmembrane transporter activity(GO:0019531)
0.0 0.9 GO:0003899 DNA-directed RNA polymerase activity(GO:0003899)
0.0 0.5 GO:0008373 sialyltransferase activity(GO:0008373)
0.0 0.3 GO:0016594 glycine binding(GO:0016594)
0.0 0.3 GO:0005035 tumor necrosis factor-activated receptor activity(GO:0005031) death receptor activity(GO:0005035)
0.0 0.2 GO:0045505 dynein intermediate chain binding(GO:0045505)
0.0 1.2 GO:0003743 translation initiation factor activity(GO:0003743)
0.0 0.2 GO:0031404 chloride ion binding(GO:0031404)
0.0 0.3 GO:0043138 3'-5' DNA helicase activity(GO:0043138)
0.0 0.0 GO:0031871 proteinase activated receptor binding(GO:0031871)
0.0 0.1 GO:1901612 phosphatidylglycerol binding(GO:1901611) cardiolipin binding(GO:1901612)
0.0 0.1 GO:0001135 transcription factor activity, RNA polymerase II transcription factor recruiting(GO:0001135)
0.0 0.2 GO:0010857 calcium-dependent protein kinase activity(GO:0010857)
0.0 0.0 GO:0004954 icosanoid receptor activity(GO:0004953) prostanoid receptor activity(GO:0004954) prostaglandin receptor activity(GO:0004955)
0.0 0.1 GO:0008417 fucosyltransferase activity(GO:0008417)
0.0 0.3 GO:0003755 peptidyl-prolyl cis-trans isomerase activity(GO:0003755)
0.0 2.5 GO:0017137 Rab GTPase binding(GO:0017137)
0.0 0.3 GO:0030553 cGMP binding(GO:0030553) 3',5'-cyclic-GMP phosphodiesterase activity(GO:0047555)
0.0 0.3 GO:0004385 guanylate kinase activity(GO:0004385)
0.0 0.0 GO:0008384 IkappaB kinase activity(GO:0008384)
0.0 0.1 GO:0086080 protein binding involved in heterotypic cell-cell adhesion(GO:0086080)
0.0 0.1 GO:0005087 Ran guanyl-nucleotide exchange factor activity(GO:0005087)
0.0 0.2 GO:0005540 hyaluronic acid binding(GO:0005540)
0.0 0.2 GO:0002161 aminoacyl-tRNA editing activity(GO:0002161)
0.0 0.5 GO:0032266 phosphatidylinositol-3-phosphate binding(GO:0032266)
0.0 0.2 GO:0004435 phosphatidylinositol phospholipase C activity(GO:0004435)
0.0 1.2 GO:0008080 N-acetyltransferase activity(GO:0008080)
0.0 0.4 GO:0008139 nuclear localization sequence binding(GO:0008139)
0.0 0.2 GO:0050431 transforming growth factor beta binding(GO:0050431)
0.0 0.2 GO:0008253 5'-nucleotidase activity(GO:0008253)
0.0 0.3 GO:0050136 NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.0 0.1 GO:0016846 carbon-sulfur lyase activity(GO:0016846)
0.0 0.3 GO:0043539 protein serine/threonine kinase activator activity(GO:0043539)
0.0 0.0 GO:0070699 type II activin receptor binding(GO:0070699)
0.0 0.1 GO:0043024 ribosomal small subunit binding(GO:0043024)
0.0 0.4 GO:0005112 Notch binding(GO:0005112)
0.0 0.2 GO:0005044 scavenger receptor activity(GO:0005044)
0.0 0.2 GO:0043422 protein kinase B binding(GO:0043422)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 3.5 PID_ARF6_PATHWAY Arf6 signaling events
0.1 1.3 PID_INTEGRIN_CS_PATHWAY Integrin family cell surface interactions
0.1 7.5 NABA_ECM_AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.0 1.8 PID_IL2_STAT5_PATHWAY IL2 signaling events mediated by STAT5
0.0 0.5 ST_G_ALPHA_S_PATHWAY G alpha s Pathway
0.0 0.3 PID_CONE_PATHWAY Visual signal transduction: Cones
0.0 0.4 PID_EPHA_FWDPATHWAY EPHA forward signaling
0.0 0.2 PID_NFKAPPAB_ATYPICAL_PATHWAY Atypical NF-kappaB pathway
0.0 0.1 SA_MMP_CYTOKINE_CONNECTION Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.0 0.3 PID_UPA_UPAR_PATHWAY Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling
0.0 0.2 PID_ATM_PATHWAY ATM pathway
0.0 0.4 PID_DNA_PK_PATHWAY DNA-PK pathway in nonhomologous end joining
0.0 0.1 SA_G2_AND_M_PHASES Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
0.0 0.9 PID_HES_HEY_PATHWAY Notch-mediated HES/HEY network
0.0 0.3 PID_PTP1B_PATHWAY Signaling events mediated by PTP1B
0.0 0.5 PID_HNF3B_PATHWAY FOXA2 and FOXA3 transcription factor networks
0.0 0.4 PID_ALPHA_SYNUCLEIN_PATHWAY Alpha-synuclein signaling
0.0 0.2 PID_IL2_1PATHWAY IL2-mediated signaling events
0.0 0.2 PID_GMCSF_PATHWAY GMCSF-mediated signaling events
0.0 0.6 PID_MYC_REPRESS_PATHWAY Validated targets of C-MYC transcriptional repression

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.1 REACTOME_SEMA3A_PLEXIN_REPULSION_SIGNALING_BY_INHIBITING_INTEGRIN_ADHESION Genes involved in SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion
0.1 0.7 REACTOME_PLATELET_CALCIUM_HOMEOSTASIS Genes involved in Platelet calcium homeostasis
0.1 1.2 REACTOME_SHC1_EVENTS_IN_EGFR_SIGNALING Genes involved in SHC1 events in EGFR signaling
0.0 0.4 REACTOME_AMINE_DERIVED_HORMONES Genes involved in Amine-derived hormones
0.0 0.9 REACTOME_SULFUR_AMINO_ACID_METABOLISM Genes involved in Sulfur amino acid metabolism
0.0 0.3 REACTOME_ENDOGENOUS_STEROLS Genes involved in Endogenous sterols
0.0 1.5 REACTOME_G1_PHASE Genes involved in G1 Phase
0.0 0.5 REACTOME_APOPTOSIS_INDUCED_DNA_FRAGMENTATION Genes involved in Apoptosis induced DNA fragmentation
0.0 0.2 REACTOME_NFKB_IS_ACTIVATED_AND_SIGNALS_SURVIVAL Genes involved in NF-kB is activated and signals survival
0.0 1.0 REACTOME_SEMA4D_IN_SEMAPHORIN_SIGNALING Genes involved in Sema4D in semaphorin signaling
0.0 0.3 REACTOME_HYALURONAN_UPTAKE_AND_DEGRADATION Genes involved in Hyaluronan uptake and degradation
0.0 1.0 REACTOME_VOLTAGE_GATED_POTASSIUM_CHANNELS Genes involved in Voltage gated Potassium channels
0.0 0.3 REACTOME_NRIF_SIGNALS_CELL_DEATH_FROM_THE_NUCLEUS Genes involved in NRIF signals cell death from the nucleus
0.0 0.1 REACTOME_SPRY_REGULATION_OF_FGF_SIGNALING Genes involved in Spry regulation of FGF signaling
0.0 0.3 REACTOME_P38MAPK_EVENTS Genes involved in p38MAPK events
0.0 0.2 REACTOME_BASE_FREE_SUGAR_PHOSPHATE_REMOVAL_VIA_THE_SINGLE_NUCLEOTIDE_REPLACEMENT_PATHWAY Genes involved in Base-free sugar-phosphate removal via the single-nucleotide replacement pathway
0.0 0.2 REACTOME_PYRIMIDINE_CATABOLISM Genes involved in Pyrimidine catabolism
0.0 0.5 REACTOME_CELL_EXTRACELLULAR_MATRIX_INTERACTIONS Genes involved in Cell-extracellular matrix interactions
0.0 0.5 REACTOME_RAS_ACTIVATION_UOPN_CA2_INFUX_THROUGH_NMDA_RECEPTOR Genes involved in Ras activation uopn Ca2+ infux through NMDA receptor
0.0 0.2 REACTOME_SIGNALING_BY_CONSTITUTIVELY_ACTIVE_EGFR Genes involved in Signaling by constitutively active EGFR
0.0 0.3 REACTOME_UNWINDING_OF_DNA Genes involved in Unwinding of DNA
0.0 0.0 REACTOME_EICOSANOID_LIGAND_BINDING_RECEPTORS Genes involved in Eicosanoid ligand-binding receptors
0.0 0.1 REACTOME_G2_M_DNA_DAMAGE_CHECKPOINT Genes involved in G2/M DNA damage checkpoint
0.0 0.2 REACTOME_PROTEOLYTIC_CLEAVAGE_OF_SNARE_COMPLEX_PROTEINS Genes involved in Proteolytic cleavage of SNARE complex proteins
0.0 0.2 REACTOME_NEF_MEDIATED_DOWNREGULATION_OF_MHC_CLASS_I_COMPLEX_CELL_SURFACE_EXPRESSION Genes involved in Nef mediated downregulation of MHC class I complex cell surface expression
0.0 0.2 REACTOME_TETRAHYDROBIOPTERIN_BH4_SYNTHESIS_RECYCLING_SALVAGE_AND_REGULATION Genes involved in Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation
0.0 0.2 REACTOME_SYNTHESIS_OF_PIPS_AT_THE_EARLY_ENDOSOME_MEMBRANE Genes involved in Synthesis of PIPs at the early endosome membrane
0.0 0.3 REACTOME_PKA_MEDIATED_PHOSPHORYLATION_OF_CREB Genes involved in PKA-mediated phosphorylation of CREB
0.0 0.2 REACTOME_GAP_JUNCTION_DEGRADATION Genes involved in Gap junction degradation
0.0 0.3 REACTOME_BRANCHED_CHAIN_AMINO_ACID_CATABOLISM Genes involved in Branched-chain amino acid catabolism
0.0 0.3 REACTOME_ANTIGEN_ACTIVATES_B_CELL_RECEPTOR_LEADING_TO_GENERATION_OF_SECOND_MESSENGERS Genes involved in Antigen Activates B Cell Receptor Leading to Generation of Second Messengers
0.0 0.5 REACTOME_INWARDLY_RECTIFYING_K_CHANNELS Genes involved in Inwardly rectifying K+ channels
0.0 0.3 REACTOME_EXTENSION_OF_TELOMERES Genes involved in Extension of Telomeres
0.0 0.2 REACTOME_GLYCOGEN_BREAKDOWN_GLYCOGENOLYSIS Genes involved in Glycogen breakdown (glycogenolysis)
0.0 0.1 REACTOME_EXTRINSIC_PATHWAY_FOR_APOPTOSIS Genes involved in Extrinsic Pathway for Apoptosis
0.0 0.3 REACTOME_SYNTHESIS_AND_INTERCONVERSION_OF_NUCLEOTIDE_DI_AND_TRIPHOSPHATES Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.0 0.1 REACTOME_ADVANCED_GLYCOSYLATION_ENDPRODUCT_RECEPTOR_SIGNALING Genes involved in Advanced glycosylation endproduct receptor signaling