---

Top targets:

Promoter	Score	Refseq	Gene Symbol	Gene Name
chr15_-_8710734	3.815	ENSMUST00000005493.7	Slc1a3	solute carrier family 1 (glial high affinity glutamate transporter), member 3
chr15_-_8710409	3.176	ENSMUST00000157065.1	Slc1a3	solute carrier family 1 (glial high affinity glutamate transporter), member 3
chr14_+_80000292	2.824	ENSMUST00000088735.3	Olfm4	olfactomedin 4
chr5_-_62766153	1.440	ENSMUST00000076623.4	Arap2	ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2
chr6_-_137169710	1.176	ENSMUST00000117919.1	Rerg	RAS-like, estrogen-regulated, growth-inhibitor
chr7_-_46667375	1.096	ENSMUST00000107669.2	Tph1	tryptophan hydroxylase 1
chr2_+_116067213	0.928	ENSMUST00000152412.1	G630016G05Rik	RIKEN cDNA G630016G05 gene
chr9_-_90255927	0.754	ENSMUST00000144646.1	Tbc1d2b	TBC1 domain family, member 2B
chr15_-_37458523	0.673	ENSMUST00000116445.2	Ncald	neurocalcin delta
chr6_+_30541582	0.614	ENSMUST00000096066.4	Cpa2	carboxypeptidase A2, pancreatic
chr5_+_66968559	0.599	ENSMUST00000127184.1	Limch1	LIM and calponin homology domains 1
chrX_-_143933089	0.571	ENSMUST00000087313.3	Dcx	doublecortin
chr2_+_109917639	0.566	ENSMUST00000046548.7 ENSMUST00000111037.2	Lgr4	leucine-rich repeat-containing G protein-coupled receptor 4
chr8_+_45885479	0.518	ENSMUST00000034053.5	Pdlim3	PDZ and LIM domain 3
chr17_+_88440711	0.507	ENSMUST00000112238.2 ENSMUST00000155640.1	Foxn2	forkhead box N2
chr2_-_116067391	0.503	ENSMUST00000140185.1	2700033N17Rik	RIKEN cDNA 2700033N17 gene
chr4_-_14621805	0.502	ENSMUST00000042221.7	Slc26a7	solute carrier family 26, member 7
chr5_+_66968416	0.498	ENSMUST00000038188.7	Limch1	LIM and calponin homology domains 1
chr18_+_37518341	0.488	ENSMUST00000097609.1	Pcdhb22	protocadherin beta 22
chr3_-_66296807	0.409	ENSMUST00000029419.7	Veph1	ventricular zone expressed PH domain-containing 1
chr3_+_5218516	0.394	ENSMUST00000175866.1	Zfhx4	zinc finger homeodomain 4
chr6_-_118479237	0.386	ENSMUST00000161170.1	Zfp9	zinc finger protein 9
chr17_-_45659312	0.382	ENSMUST00000120717.1	Capn11	calpain 11
chr13_-_81710937	0.354	ENSMUST00000161920.1 ENSMUST00000048993.5	Polr3g	polymerase (RNA) III (DNA directed) polypeptide G
chr9_-_103228420	0.344	ENSMUST00000126359.1	Trf	transferrin
chr2_-_177267036	0.333	ENSMUST00000108963.1	Gm14409	predicted gene 14409
chr1_-_134955847	0.333	ENSMUST00000168381.1	Ppp1r12b	protein phosphatase 1, regulatory (inhibitor) subunit 12B
chr8_+_23411490	0.329	ENSMUST00000033952.7	Sfrp1	secreted frizzled-related protein 1
chr4_+_108719649	0.316	ENSMUST00000178992.1	3110021N24Rik	RIKEN cDNA 3110021N24 gene
chr13_+_42681513	0.302	ENSMUST00000149235.1	Phactr1	phosphatase and actin regulator 1
chr10_+_97482350	0.301	ENSMUST00000163448.2	Dcn	decorin
chr15_+_98571004	0.293	ENSMUST00000023728.6	4930415O20Rik	RIKEN cDNA 4930415O20 gene
chr17_-_36032682	0.288	ENSMUST00000102678.4	H2-T23	histocompatibility 2, T region locus 23
chr10_-_117148474	0.286	ENSMUST00000020381.3	Frs2	fibroblast growth factor receptor substrate 2
chr8_+_94152607	0.280	ENSMUST00000034211.8	Mt3	metallothionein 3
chr12_-_87775755	0.274	ENSMUST00000164517.2	Gm21319	predicted gene, 21319
chr13_+_83732438	0.273	ENSMUST00000182701.1	C130071C03Rik	RIKEN cDNA C130071C03 gene
chr13_+_43785107	0.272	ENSMUST00000015540.2	Cd83	CD83 antigen
chr2_+_69897255	0.271	ENSMUST00000131553.1	Ubr3	ubiquitin protein ligase E3 component n-recognin 3
chr3_+_5218589	0.270	ENSMUST00000177488.1	Zfhx4	zinc finger homeodomain 4
chr4_-_82850721	0.269	ENSMUST00000139401.1	Zdhhc21	zinc finger, DHHC domain containing 21
chr2_-_45117349	0.263	ENSMUST00000176438.2	Zeb2	zinc finger E-box binding homeobox 2
chr10_-_86011833	0.254	ENSMUST00000105304.1 ENSMUST00000061699.5	Bpifc	BPI fold containing family C
chr19_+_5474681	0.251	ENSMUST00000165485.1 ENSMUST00000166253.1 ENSMUST00000167371.1 ENSMUST00000167855.1 ENSMUST00000070118.7	Efemp2	epidermal growth factor-containing fibulin-like extracellular matrix protein 2
chr4_-_14621494	0.250	ENSMUST00000149633.1	Slc26a7	solute carrier family 26, member 7
chr19_+_55895508	0.236	ENSMUST00000111646.1	Tcf7l2	transcription factor 7 like 2, T cell specific, HMG box
chr14_+_54431597	0.227	ENSMUST00000089688.4	Mmp14	matrix metallopeptidase 14 (membrane-inserted)
chr10_+_116018213	0.224	ENSMUST00000063470.4	Ptprr	protein tyrosine phosphatase, receptor type, R
chr5_+_29195983	0.222	ENSMUST00000160888.1 ENSMUST00000159272.1 ENSMUST00000001247.5 ENSMUST00000161398.1 ENSMUST00000160246.1	Rnf32	ring finger protein 32
chr2_+_110597298	0.213	ENSMUST00000045972.6 ENSMUST00000111026.2	Slc5a12	solute carrier family 5 (sodium/glucose cotransporter), member 12
chr19_-_32196393	0.211	ENSMUST00000151822.1	Sgms1	sphingomyelin synthase 1
chr1_-_134955908	0.206	ENSMUST00000045665.6 ENSMUST00000086444.4 ENSMUST00000112163.1	Ppp1r12b	protein phosphatase 1, regulatory (inhibitor) subunit 12B
chr9_-_55919605	0.199	ENSMUST00000037408.8	Scaper	S phase cyclin A-associated protein in the ER
chr6_+_145934113	0.194	ENSMUST00000032383.7	Sspn	sarcospan
chr4_+_102589687	0.188	ENSMUST00000097949.4 ENSMUST00000106901.1	Pde4b	phosphodiesterase 4B, cAMP specific
chr14_-_36919314	0.188	ENSMUST00000182797.1	Ccser2	coiled-coil serine rich 2
chr5_-_62765618	0.184	ENSMUST00000159470.1	Arap2	ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2
chr11_+_29373618	0.179	ENSMUST00000040182.6 ENSMUST00000109477.1	Ccdc88a	coiled coil domain containing 88A
chr1_-_72284248	0.179	ENSMUST00000097698.4 ENSMUST00000027381.6	Pecr	peroxisomal trans-2-enoyl-CoA reductase
chr4_-_14621669	0.158	ENSMUST00000143105.1	Slc26a7	solute carrier family 26, member 7
chr7_+_103550368	0.154	ENSMUST00000106888.1	Olfr613	olfactory receptor 613
chr2_-_164171113	0.152	ENSMUST00000045196.3	Kcns1	K+ voltage-gated channel, subfamily S, 1
chr7_-_83550258	0.150	ENSMUST00000177929.1	Gm10610	predicted gene 10610
chr19_-_41933276	0.142	ENSMUST00000075280.4 ENSMUST00000112123.2	Exosc1	exosome component 1
chr11_-_82890541	0.132	ENSMUST00000092844.6 ENSMUST00000021033.9 ENSMUST00000018985.8	Rad51d	RAD51 homolog D
chr3_+_5218546	0.129	ENSMUST00000026284.6	Zfhx4	zinc finger homeodomain 4
chr3_+_121291725	0.122	ENSMUST00000039442.7	Alg14	asparagine-linked glycosylation 14
chr6_+_63255971	0.120	ENSMUST00000159561.1 ENSMUST00000095852.3	Grid2	glutamate receptor, ionotropic, delta 2
chrX_+_16619698	0.115	ENSMUST00000026013.5	Maoa	monoamine oxidase A
chr14_+_64589802	0.110	ENSMUST00000180610.1	A930011O12Rik	RIKEN cDNA A930011O12 gene
chrX_-_143933204	0.100	ENSMUST00000112851.1 ENSMUST00000112856.2 ENSMUST00000033642.3	Dcx	doublecortin
chr17_-_29007925	0.093	ENSMUST00000009138.5 ENSMUST00000119274.1	Stk38	serine/threonine kinase 38
chr9_+_110052016	0.089	ENSMUST00000164930.1 ENSMUST00000163979.1	Map4	microtubule-associated protein 4
chr9_+_113812547	0.086	ENSMUST00000166734.2 ENSMUST00000111838.2 ENSMUST00000163895.2	Clasp2	CLIP associating protein 2
chr18_+_55057557	0.083	ENSMUST00000181765.1	Gm4221	predicted gene 4221
chr2_+_32606946	0.076	ENSMUST00000113290.1	St6galnac6	ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 6
chr7_-_38019505	0.069	ENSMUST00000085513.4	Uri1	URI1, prefoldin-like chaperone
chr4_+_100478806	0.067	ENSMUST00000133493.2 ENSMUST00000092730.3 ENSMUST00000106979.3	Ube2u	ubiquitin-conjugating enzyme E2U (putative)
chr2_+_125136692	0.065	ENSMUST00000099452.2	Ctxn2	cortexin 2
chr18_+_32067729	0.064	ENSMUST00000025243.3	Iws1	IWS1 homolog (S. cerevisiae)
chr7_+_126950687	0.053	ENSMUST00000106333.1	Sez6l2	seizure related 6 homolog like 2
chr14_-_108914237	0.047	ENSMUST00000100322.2	Slitrk1	SLIT and NTRK-like family, member 1
chr2_+_69897220	0.041	ENSMUST00000055758.9 ENSMUST00000112251.2	Ubr3	ubiquitin protein ligase E3 component n-recognin 3
chr4_+_145585166	0.029	ENSMUST00000105739.1 ENSMUST00000119718.1	Gm13212	predicted gene 13212
chr18_-_3281036	0.028	ENSMUST00000049942.6 ENSMUST00000139537.1 ENSMUST00000124747.1	Crem	cAMP responsive element modulator
chr2_+_32606979	0.027	ENSMUST00000113289.1 ENSMUST00000095044.3	St6galnac6	ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 6
chrM_+_9870	0.026	ENSMUST00000084013.1	mt-Nd4l	mitochondrially encoded NADH dehydrogenase 4L
chr6_+_37870786	0.023	ENSMUST00000120428.1 ENSMUST00000031859.7	Trim24	tripartite motif-containing 24
chr10_-_20725023	0.020	ENSMUST00000020165.7	Pde7b	phosphodiesterase 7B
chr2_+_23069210	0.014	ENSMUST00000155602.1	Acbd5	acyl-Coenzyme A binding domain containing 5
chr19_-_53944621	0.009	ENSMUST00000135402.2	Bbip1	BBSome interacting protein 1
chr15_-_75905349	0.007	ENSMUST00000127550.1	Eef1d	eukaryotic translation elongation factor 1 delta (guanine nucleotide exchange protein)
chr2_-_79456750	0.006	ENSMUST00000041099.4	Neurod1	neurogenic differentiation 1
chrM_-_14060	0.004	ENSMUST00000082419.1	mt-Nd6	mitochondrially encoded NADH dehydrogenase 6
chr3_-_59220150	0.003	ENSMUST00000170388.1	P2ry12	purinergic receptor P2Y, G-protein coupled 12
chrM_+_14138	0.003	ENSMUST00000082421.1	mt-Cytb	mitochondrially encoded cytochrome b

Gene overrepresentation in biological_process category:

Log-likelihood per target	Total log-likelihood	Term	Description
1.7	7.0	GO:0043490	malate-aspartate shuttle(GO:0043490)
0.2	0.6	GO:0072204	cell-cell signaling involved in kidney development(GO:0060995) Wnt signaling pathway involved in kidney development(GO:0061289) canonical Wnt signaling pathway involved in metanephric kidney development(GO:0061290) cell-cell signaling involved in metanephros development(GO:0072204)
0.1	1.1	GO:1901162	serotonin biosynthetic process(GO:0042427) primary amino compound biosynthetic process(GO:1901162)
0.1	0.9	GO:0019532	oxalate transport(GO:0019532)
0.1	0.3	GO:1904956	regulation of midbrain dopaminergic neuron differentiation(GO:1904956) regulation of planar cell polarity pathway involved in axis elongation(GO:2000040) negative regulation of planar cell polarity pathway involved in axis elongation(GO:2000041)
0.1	0.3	GO:2000564	antigen processing and presentation of endogenous peptide antigen via MHC class Ib via ER pathway(GO:0002488) antigen processing and presentation of endogenous peptide antigen via MHC class Ib via ER pathway, TAP-dependent(GO:0002489) CD8-positive, alpha-beta T cell proliferation(GO:0035740) regulation of CD8-positive, alpha-beta T cell proliferation(GO:2000564) positive regulation of CD8-positive, alpha-beta T cell activation(GO:2001187)
0.1	0.3	GO:0097212	lysosomal membrane organization(GO:0097212)
0.1	0.3	GO:0071596	ubiquitin-dependent protein catabolic process via the N-end rule pathway(GO:0071596)
0.1	0.3	GO:0046619	optic placode formation involved in camera-type eye formation(GO:0046619)
0.1	2.8	GO:1900026	positive regulation of substrate adhesion-dependent cell spreading(GO:1900026)
0.1	0.2	GO:0038128	ERBB2 signaling pathway(GO:0038128)
0.0	0.3	GO:0032713	negative regulation of interleukin-4 production(GO:0032713)
0.0	0.7	GO:0048672	positive regulation of collateral sprouting(GO:0048672)
0.0	0.3	GO:1903056	positive regulation of lens fiber cell differentiation(GO:1902748) regulation of melanosome organization(GO:1903056)
0.0	0.3	GO:1900747	negative regulation of vascular endothelial growth factor signaling pathway(GO:1900747)
0.0	0.3	GO:0098707	positive regulation of oligodendrocyte progenitor proliferation(GO:0070447) ferrous iron import into cell(GO:0097460) ferrous iron import across plasma membrane(GO:0098707)
0.0	0.2	GO:1903566	positive regulation of protein localization to cilium(GO:1903566)
0.0	0.2	GO:0048625	myoblast fate commitment(GO:0048625)
0.0	0.1	GO:0042420	dopamine catabolic process(GO:0042420)
0.0	0.3	GO:0018230	peptidyl-L-cysteine S-palmitoylation(GO:0018230) peptidyl-S-diacylglycerol-L-cysteine biosynthetic process from peptidyl-cysteine(GO:0018231)
0.0	0.2	GO:0006686	sphingomyelin biosynthetic process(GO:0006686)
0.0	0.1	GO:0000707	meiotic DNA recombinase assembly(GO:0000707)
0.0	0.1	GO:0051012	microtubule sliding(GO:0051012) negative regulation of nonmotile primary cilium assembly(GO:1902856)
0.0	0.2	GO:0035988	chondrocyte proliferation(GO:0035988)
0.0	0.2	GO:1901898	negative regulation of relaxation of cardiac muscle(GO:1901898)
0.0	0.2	GO:0030497	fatty acid elongation(GO:0030497)
0.0	0.1	GO:0090091	positive regulation of extracellular matrix disassembly(GO:0090091) negative regulation of wound healing, spreading of epidermal cells(GO:1903690)
0.0	0.1	GO:0001574	ganglioside biosynthetic process(GO:0001574)
0.0	0.1	GO:0006488	dolichol-linked oligosaccharide biosynthetic process(GO:0006488)

Gene overrepresentation in cellular_component category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.2	2.8	GO:0042581	specific granule(GO:0042581)
0.0	0.3	GO:0097433	dense body(GO:0097433)
0.0	0.2	GO:0044352	pinosome(GO:0044352) macropinosome(GO:0044354)
0.0	7.3	GO:0043197	dendritic spine(GO:0043197)
0.0	0.1	GO:0033063	Rad51B-Rad51C-Rad51D-XRCC2 complex(GO:0033063)
0.0	0.2	GO:0070369	beta-catenin-TCF7L2 complex(GO:0070369)
0.0	0.3	GO:0042612	MHC class I protein complex(GO:0042612)
0.0	0.1	GO:0030981	cortical microtubule cytoskeleton(GO:0030981)
0.0	0.2	GO:0000138	Golgi trans cisterna(GO:0000138)
0.0	0.4	GO:0005666	DNA-directed RNA polymerase III complex(GO:0005666)
0.0	0.3	GO:0098644	complex of collagen trimers(GO:0098644)
0.0	0.1	GO:0000176	nuclear exosome (RNase complex)(GO:0000176)
0.0	0.5	GO:0031672	A band(GO:0031672)
0.0	0.5	GO:0032391	photoreceptor connecting cilium(GO:0032391)
0.0	0.2	GO:0016010	dystrophin-associated glycoprotein complex(GO:0016010) glycoprotein complex(GO:0090665)

Gene overrepresentation in molecular_function category:

Log-likelihood per target	Total log-likelihood	Term	Description
1.2	7.0	GO:0015501	glutamate:sodium symporter activity(GO:0015501)
0.4	1.1	GO:0004510	tryptophan 5-monooxygenase activity(GO:0004510)
0.1	0.9	GO:0019531	secondary active sulfate transmembrane transporter activity(GO:0008271) oxalate transmembrane transporter activity(GO:0019531)
0.1	0.2	GO:0019166	trans-2-enoyl-CoA reductase (NADPH) activity(GO:0019166)
0.0	0.3	GO:0015091	ferric iron transmembrane transporter activity(GO:0015091) trivalent inorganic cation transmembrane transporter activity(GO:0072510)
0.0	0.6	GO:0016500	protein-hormone receptor activity(GO:0016500)
0.0	0.2	GO:0033188	sphingomyelin synthase activity(GO:0033188) ceramide cholinephosphotransferase activity(GO:0047493)
0.0	0.3	GO:0046703	natural killer cell lectin-like receptor binding(GO:0046703)
0.0	0.6	GO:0004181	metallocarboxypeptidase activity(GO:0004181)
0.0	1.6	GO:0005547	phosphatidylinositol-3,4,5-trisphosphate binding(GO:0005547)
0.0	0.3	GO:0005068	transmembrane receptor protein tyrosine kinase adaptor activity(GO:0005068)
0.0	0.2	GO:0015129	lactate transmembrane transporter activity(GO:0015129)
0.0	0.1	GO:0051378	primary amine oxidase activity(GO:0008131) serotonin binding(GO:0051378)
0.0	0.2	GO:0004984	olfactory receptor activity(GO:0004984)
0.0	0.4	GO:0004198	calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.0	0.7	GO:0043014	alpha-tubulin binding(GO:0043014)
0.0	0.1	GO:0000150	recombinase activity(GO:0000150)
0.0	0.5	GO:0008307	structural constituent of muscle(GO:0008307)
0.0	0.1	GO:0001665	alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity(GO:0001665)
0.0	0.3	GO:0042813	Wnt-activated receptor activity(GO:0042813)
0.0	0.2	GO:0070016	gamma-catenin binding(GO:0045295) armadillo repeat domain binding(GO:0070016)
0.0	0.3	GO:0008157	protein phosphatase 1 binding(GO:0008157)
0.0	0.2	GO:0070006	metalloaminopeptidase activity(GO:0070006)

Gene overrepresentation in C2:CP category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.0	1.6	PID_ARF6_PATHWAY	Arf6 signaling events
0.0	0.7	PID_LIS1_PATHWAY	Lissencephaly gene (LIS1) in neuronal migration and development

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	6.4	REACTOME_AMINO_ACID_AND_OLIGOPEPTIDE_SLC_TRANSPORTERS	Genes involved in Amino acid and oligopeptide SLC transporters
0.1	1.1	REACTOME_AMINE_DERIVED_HORMONES	Genes involved in Amine-derived hormones
0.0	0.7	REACTOME_IONOTROPIC_ACTIVITY_OF_KAINATE_RECEPTORS	Genes involved in Ionotropic activity of Kainate Receptors
0.0	0.3	REACTOME_CS_DS_DEGRADATION	Genes involved in CS/DS degradation
0.0	0.9	REACTOME_TRANSPORT_OF_INORGANIC_CATIONS_ANIONS_AND_AMINO_ACIDS_OLIGOPEPTIDES	Genes involved in Transport of inorganic cations/anions and amino acids/oligopeptides
0.0	0.2	REACTOME_DEGRADATION_OF_THE_EXTRACELLULAR_MATRIX	Genes involved in Degradation of the extracellular matrix
0.0	0.1	REACTOME_MRNA_DECAY_BY_3_TO_5_EXORIBONUCLEASE	Genes involved in mRNA Decay by 3' to 5' Exoribonuclease
0.0	0.3	REACTOME_PROLONGED_ERK_ACTIVATION_EVENTS	Genes involved in Prolonged ERK activation events

---