Motif ID: Hoxa9_Hoxb9

Z-value: 0.577

Transcription factors associated with Hoxa9_Hoxb9:

Gene SymbolEntrez IDGene Name
Hoxa9 ENSMUSG00000038227.9 Hoxa9
Hoxb9 ENSMUSG00000020875.8 Hoxb9






Network of associatons between targets according to the STRING database.



First level regulatory network of Hoxa9_Hoxb9

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr19_-_57197435 5.472 ENSMUST00000111550.1
Ablim1
actin-binding LIM protein 1
chr19_-_57197377 5.382 ENSMUST00000111546.1
Ablim1
actin-binding LIM protein 1
chr6_+_49822710 4.482 ENSMUST00000031843.6
Npy
neuropeptide Y
chr19_-_57197496 2.468 ENSMUST00000111544.1
Ablim1
actin-binding LIM protein 1
chr13_+_16014457 2.459 ENSMUST00000164993.1
Inhba
inhibin beta-A
chr7_-_142661858 2.408 ENSMUST00000145896.2
Igf2
insulin-like growth factor 2
chr19_-_57197556 2.299 ENSMUST00000099294.2
Ablim1
actin-binding LIM protein 1
chr8_+_93810832 1.519 ENSMUST00000034198.8
ENSMUST00000125716.1
Gnao1

guanine nucleotide binding protein, alpha O

chr11_-_79504078 1.427 ENSMUST00000164465.2
Omg
oligodendrocyte myelin glycoprotein
chr2_-_33087169 1.400 ENSMUST00000102810.3
Garnl3
GTPase activating RANGAP domain-like 3
chr2_-_33086366 1.370 ENSMUST00000049618.2
Garnl3
GTPase activating RANGAP domain-like 3
chr11_-_109298066 1.321 ENSMUST00000106706.1
Rgs9
regulator of G-protein signaling 9
chr18_-_31447383 1.230 ENSMUST00000025110.3
Syt4
synaptotagmin IV
chr19_-_45812291 1.224 ENSMUST00000086993.4
Kcnip2
Kv channel-interacting protein 2
chr16_+_91225550 1.201 ENSMUST00000035608.8
Olig2
oligodendrocyte transcription factor 2
chr2_+_125136692 1.188 ENSMUST00000099452.2
Ctxn2
cortexin 2
chr16_-_52454074 1.118 ENSMUST00000023312.7
Alcam
activated leukocyte cell adhesion molecule
chr3_+_138065052 1.100 ENSMUST00000163080.2
1110002E22Rik
RIKEN cDNA 1110002E22 gene
chr18_+_37400845 1.045 ENSMUST00000057228.1
Pcdhb9
protocadherin beta 9
chr13_-_91388079 1.042 ENSMUST00000181054.1
A830009L08Rik
RIKEN cDNA A830009L08 gene
chr4_-_49597860 1.016 ENSMUST00000042750.2
Tmem246
transmembrane protein 246
chr15_-_79062866 0.947 ENSMUST00000151889.1
ENSMUST00000040676.4
Ankrd54

ankyrin repeat domain 54

chrX_+_159840463 0.928 ENSMUST00000112451.1
ENSMUST00000112453.2
Sh3kbp1

SH3-domain kinase binding protein 1

chr4_+_74013442 0.903 ENSMUST00000098006.2
ENSMUST00000084474.5
Frmd3

FERM domain containing 3

chr3_+_98280427 0.833 ENSMUST00000090746.2
ENSMUST00000120541.1
Hmgcs2

3-hydroxy-3-methylglutaryl-Coenzyme A synthase 2

chr18_-_31317043 0.815 ENSMUST00000139924.1
ENSMUST00000153060.1
Rit2

Ras-like without CAAX 2

chr7_+_28277706 0.755 ENSMUST00000094651.2
Eid2b
EP300 interacting inhibitor of differentiation 2B
chr7_+_28693997 0.717 ENSMUST00000108280.1
Fbxo27
F-box protein 27
chr2_+_32395896 0.648 ENSMUST00000028162.3
Ptges2
prostaglandin E synthase 2
chr2_-_45112890 0.588 ENSMUST00000076836.6
Zeb2
zinc finger E-box binding homeobox 2
chr3_-_113574242 0.582 ENSMUST00000142505.2
Amy1
amylase 1, salivary
chr3_+_84952146 0.574 ENSMUST00000029727.7
Fbxw7
F-box and WD-40 domain protein 7
chr15_+_85510812 0.570 ENSMUST00000079690.2
Gm4825
predicted pseudogene 4825
chr19_-_7341848 0.567 ENSMUST00000171393.1
Mark2
MAP/microtubule affinity-regulating kinase 2
chr7_+_142533012 0.557 ENSMUST00000038675.6
Mrpl23
mitochondrial ribosomal protein L23
chr17_-_91092715 0.549 ENSMUST00000160800.2
ENSMUST00000159778.1
ENSMUST00000160844.3
Nrxn1


neurexin I


chr7_-_127449109 0.549 ENSMUST00000053392.4
Zfp689
zinc finger protein 689
chr8_+_112570043 0.537 ENSMUST00000034225.6
ENSMUST00000118171.1
Cntnap4

contactin associated protein-like 4

chr7_-_127448993 0.534 ENSMUST00000106299.1
Zfp689
zinc finger protein 689
chr10_-_63927434 0.527 ENSMUST00000079279.3
Gm10118
predicted gene 10118
chr6_+_51523901 0.509 ENSMUST00000049152.8
Snx10
sorting nexin 10
chr2_-_58052832 0.498 ENSMUST00000090940.5
Ermn
ermin, ERM-like protein
chr5_-_66514815 0.477 ENSMUST00000161879.1
ENSMUST00000159357.1
Apbb2

amyloid beta (A4) precursor protein-binding, family B, member 2

chr2_-_80447625 0.473 ENSMUST00000028389.3
Frzb
frizzled-related protein
chr6_-_97148908 0.455 ENSMUST00000142116.1
ENSMUST00000113387.1
Eogt

EGF domain-specific O-linked N-acetylglucosamine (GlcNAc) transferase

chr9_+_64235201 0.444 ENSMUST00000039011.3
Uchl4
ubiquitin carboxyl-terminal esterase L4
chr6_-_143947061 0.441 ENSMUST00000124233.1
Sox5
SRY-box containing gene 5
chr7_-_30232186 0.414 ENSMUST00000006254.5
Tbcb
tubulin folding cofactor B
chr7_+_56050135 0.412 ENSMUST00000076226.6
Herc2
hect (homologous to the E6-AP (UBE3A) carboxyl terminus) domain and RCC1 (CHC1)-like domain (RLD) 2
chr2_+_180967291 0.404 ENSMUST00000108859.1
Arfgap1
ADP-ribosylation factor GTPase activating protein 1
chr1_+_89454769 0.391 ENSMUST00000027521.8
ENSMUST00000074945.5
Agap1

ArfGAP with GTPase domain, ankyrin repeat and PH domain 1

chr9_+_75311395 0.378 ENSMUST00000076889.6
Gnb5
guanine nucleotide binding protein (G protein), beta 5
chr7_+_30231884 0.376 ENSMUST00000019882.9
Polr2i
polymerase (RNA) II (DNA directed) polypeptide I
chr15_+_81936753 0.375 ENSMUST00000038757.7
Csdc2
cold shock domain containing C2, RNA binding
chr6_-_143947092 0.367 ENSMUST00000144289.1
ENSMUST00000111748.1
Sox5

SRY-box containing gene 5

chr19_-_56548122 0.360 ENSMUST00000026063.5
ENSMUST00000182276.1
Dclre1a

DNA cross-link repair 1A, PSO2 homolog (S. cerevisiae)

chr4_+_44012661 0.358 ENSMUST00000107849.3
ENSMUST00000107851.3
ENSMUST00000107845.3
Clta


clathrin, light polypeptide (Lca)


chr7_+_110768169 0.345 ENSMUST00000170374.1
Ampd3
adenosine monophosphate deaminase 3
chrX_-_134541847 0.343 ENSMUST00000054213.4
Timm8a1
translocase of inner mitochondrial membrane 8A1
chr1_+_66386968 0.340 ENSMUST00000145419.1
Map2
microtubule-associated protein 2
chr7_+_43690418 0.339 ENSMUST00000056329.6
Klk14
kallikrein related-peptidase 14
chr4_+_44012638 0.335 ENSMUST00000107847.3
ENSMUST00000170241.1
Clta

clathrin, light polypeptide (Lca)

chr11_-_109298090 0.334 ENSMUST00000106704.2
Rgs9
regulator of G-protein signaling 9
chr10_-_80590292 0.315 ENSMUST00000003436.5
Abhd17a
abhydrolase domain containing 17A
chr2_-_31845925 0.310 ENSMUST00000028188.7
Fibcd1
fibrinogen C domain containing 1
chr19_-_7341792 0.310 ENSMUST00000164205.1
ENSMUST00000165286.1
ENSMUST00000168324.1
ENSMUST00000032557.8
Mark2



MAP/microtubule affinity-regulating kinase 2



chr17_-_6621267 0.305 ENSMUST00000115772.3
Tmem181c-ps
transmembrane protein 181C, pseudogene
chr14_-_70323783 0.298 ENSMUST00000151011.1
Slc39a14
solute carrier family 39 (zinc transporter), member 14
chr7_+_45062429 0.278 ENSMUST00000107830.1
ENSMUST00000003513.3
ENSMUST00000107829.1
ENSMUST00000150609.1
Nosip



nitric oxide synthase interacting protein



chr5_-_32746317 0.270 ENSMUST00000135248.1
Pisd
phosphatidylserine decarboxylase
chr5_+_145204523 0.258 ENSMUST00000085671.3
ENSMUST00000031601.7
Zkscan5

zinc finger with KRAB and SCAN domains 5

chr11_-_109472611 0.257 ENSMUST00000168740.1
Slc16a6
solute carrier family 16 (monocarboxylic acid transporters), member 6
chr5_-_73191848 0.256 ENSMUST00000176910.1
Fryl
furry homolog-like (Drosophila)
chr3_+_108591279 0.255 ENSMUST00000051145.8
ENSMUST00000139626.1
Wdr47

WD repeat domain 47

chr14_+_20674311 0.234 ENSMUST00000048657.8
Sec24c
Sec24 related gene family, member C (S. cerevisiae)
chr9_+_122351555 0.227 ENSMUST00000156520.1
Abhd5
abhydrolase domain containing 5
chr3_-_96905294 0.208 ENSMUST00000029738.7
Gpr89
G protein-coupled receptor 89
chr19_-_56548013 0.193 ENSMUST00000182059.1
Dclre1a
DNA cross-link repair 1A, PSO2 homolog (S. cerevisiae)
chr8_-_111992258 0.174 ENSMUST00000034427.5
ENSMUST00000139820.1
Adat1

adenosine deaminase, tRNA-specific 1

chr9_+_92309362 0.169 ENSMUST00000098477.1
ENSMUST00000150594.1
1700057G04Rik

RIKEN cDNA 1700057G04 gene

chr3_-_95106907 0.165 ENSMUST00000107233.2
Pip5k1a
phosphatidylinositol-4-phosphate 5-kinase, type 1 alpha
chr5_+_31452427 0.157 ENSMUST00000076264.4
Zfp512
zinc finger protein 512
chr6_+_104492790 0.152 ENSMUST00000161446.1
ENSMUST00000161070.1
ENSMUST00000089215.5
Cntn6


contactin 6


chr11_-_115933464 0.146 ENSMUST00000021097.3
Recql5
RecQ protein-like 5
chr7_-_101870778 0.146 ENSMUST00000001882.4
ENSMUST00000126204.1
ENSMUST00000155311.1
ENSMUST00000106983.1
ENSMUST00000123630.1
Folr1




folate receptor 1 (adult)




chr2_-_165287755 0.144 ENSMUST00000109298.1
ENSMUST00000109299.1
ENSMUST00000130393.1
ENSMUST00000017808.7
ENSMUST00000131409.1
ENSMUST00000156134.1
ENSMUST00000133961.1
Slc35c2






solute carrier family 35, member C2






chr5_-_145201829 0.135 ENSMUST00000162220.1
ENSMUST00000031632.8
Zkscan14

zinc finger with KRAB and SCAN domains 14

chr8_-_33843562 0.122 ENSMUST00000183062.1
Rbpms
RNA binding protein gene with multiple splicing
chr6_-_124965207 0.118 ENSMUST00000148485.1
Cops7a
COP9 (constitutive photomorphogenic) homolog, subunit 7a (Arabidopsis thaliana)
chr19_+_44203265 0.107 ENSMUST00000026220.5
Scd3
stearoyl-coenzyme A desaturase 3
chr9_-_19928282 0.104 ENSMUST00000082002.5
Gm7808
predicted pseudogene 7808
chr17_-_45572495 0.095 ENSMUST00000130406.1
Hsp90ab1
heat shock protein 90 alpha (cytosolic), class B member 1
chr1_-_65051119 0.091 ENSMUST00000161960.1
ENSMUST00000087359.5
Cryge

crystallin, gamma E

chr9_-_101198999 0.090 ENSMUST00000066773.7
Ppp2r3a
protein phosphatase 2, regulatory subunit B'', alpha
chr3_+_66985680 0.080 ENSMUST00000065047.6
Rsrc1
arginine/serine-rich coiled-coil 1
chr2_-_67433181 0.078 ENSMUST00000180773.1
Gm26727
predicted gene, 26727
chr14_+_105681824 0.077 ENSMUST00000073238.6
Gm10076
predicted gene 10076
chr15_+_81936911 0.074 ENSMUST00000135663.1
Csdc2
cold shock domain containing C2, RNA binding
chr3_-_96197580 0.068 ENSMUST00000016087.3
Bola1
bolA-like 1 (E. coli)
chr4_-_136053343 0.065 ENSMUST00000102536.4
Rpl11
ribosomal protein L11
chr3_+_66985947 0.065 ENSMUST00000161726.1
ENSMUST00000160504.1
Rsrc1

arginine/serine-rich coiled-coil 1

chr3_+_66985647 0.061 ENSMUST00000162362.1
ENSMUST00000065074.7
Rsrc1

arginine/serine-rich coiled-coil 1

chr9_+_121366958 0.057 ENSMUST00000045903.6
Trak1
trafficking protein, kinesin binding 1
chr6_+_79818031 0.040 ENSMUST00000179797.1
Gm20594
predicted gene, 20594
chr5_+_137787769 0.024 ENSMUST00000035852.7
Zcwpw1
zinc finger, CW type with PWWP domain 1
chr6_+_147042755 0.022 ENSMUST00000036111.7
Mrps35
mitochondrial ribosomal protein S35
chr3_+_24333046 0.022 ENSMUST00000077389.6
Gm7536
predicted gene 7536
chr3_+_66985700 0.014 ENSMUST00000046542.6
ENSMUST00000162693.1
Rsrc1

arginine/serine-rich coiled-coil 1

chr17_+_33638056 0.010 ENSMUST00000052079.7
Pram1
PML-RAR alpha-regulated adaptor molecule 1
chr5_+_34999111 0.010 ENSMUST00000114283.1
Rgs12
regulator of G-protein signaling 12
chr16_-_17531019 0.008 ENSMUST00000142666.1
ENSMUST00000100125.3
Thap7

THAP domain containing 7

chr8_+_9977707 0.005 ENSMUST00000139793.1
ENSMUST00000048216.5
Abhd13

abhydrolase domain containing 13


Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 2.5 GO:0042636 negative regulation of hair cycle(GO:0042636) progesterone secretion(GO:0042701) negative regulation of hair follicle development(GO:0051799) positive regulation of ovulation(GO:0060279)
0.4 1.2 GO:0021529 spinal cord oligodendrocyte cell differentiation(GO:0021529) spinal cord oligodendrocyte cell fate specification(GO:0021530)
0.3 2.4 GO:0038028 insulin receptor signaling pathway via phosphatidylinositol 3-kinase(GO:0038028)
0.3 4.5 GO:0032098 regulation of appetite(GO:0032098)
0.2 1.2 GO:0045163 clustering of voltage-gated potassium channels(GO:0045163)
0.2 15.3 GO:0030032 lamellipodium assembly(GO:0030032)
0.2 0.8 GO:0032489 regulation of Cdc42 protein signal transduction(GO:0032489)
0.2 0.5 GO:0070366 regulation of hepatocyte differentiation(GO:0070366)
0.2 1.2 GO:2000301 negative regulation of synaptic vesicle exocytosis(GO:2000301)
0.1 0.5 GO:0090126 protein complex assembly involved in synapse maturation(GO:0090126)
0.1 0.4 GO:0001193 maintenance of transcriptional fidelity during DNA-templated transcription elongation(GO:0001192) maintenance of transcriptional fidelity during DNA-templated transcription elongation from RNA polymerase II promoter(GO:0001193)
0.1 0.8 GO:0060164 regulation of timing of neuron differentiation(GO:0060164)
0.1 0.6 GO:1903378 positive regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway(GO:1903378)
0.1 0.6 GO:1903056 melanocyte migration(GO:0097324) positive regulation of lens fiber cell differentiation(GO:1902748) regulation of melanosome organization(GO:1903056)
0.1 3.6 GO:0007212 dopamine receptor signaling pathway(GO:0007212)
0.1 0.6 GO:0031848 protection from non-homologous end joining at telomere(GO:0031848)
0.1 1.4 GO:0032291 central nervous system myelination(GO:0022010) axon ensheathment in central nervous system(GO:0032291)
0.1 0.2 GO:0010891 negative regulation of sequestering of triglyceride(GO:0010891) positive regulation of triglyceride catabolic process(GO:0010898)
0.0 0.3 GO:0032264 IMP salvage(GO:0032264)
0.0 0.3 GO:0007320 insemination(GO:0007320)
0.0 0.5 GO:2000821 regulation of grooming behavior(GO:2000821)
0.0 0.3 GO:0090527 actin filament reorganization(GO:0090527)
0.0 0.1 GO:1990414 replication-born double-strand break repair via sister chromatid exchange(GO:1990414)
0.0 0.1 GO:0046655 folic acid metabolic process(GO:0046655)
0.0 0.1 GO:0015786 UDP-glucose transport(GO:0015786)
0.0 0.6 GO:0001516 prostaglandin biosynthetic process(GO:0001516) prostanoid biosynthetic process(GO:0046457)
0.0 0.1 GO:0097278 transforming growth factor beta activation(GO:0036363) complement-dependent cytotoxicity(GO:0097278)
0.0 0.7 GO:0048268 clathrin coat assembly(GO:0048268)
0.0 0.1 GO:0007525 somatic muscle development(GO:0007525)
0.0 0.8 GO:0008299 isoprenoid biosynthetic process(GO:0008299)
0.0 0.3 GO:0071578 zinc II ion transmembrane import(GO:0071578)
0.0 0.1 GO:1903966 monounsaturated fatty acid metabolic process(GO:1903964) monounsaturated fatty acid biosynthetic process(GO:1903966)
0.0 0.2 GO:0017121 phospholipid scrambling(GO:0017121)
0.0 1.1 GO:0007157 heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0007157)
0.0 0.1 GO:2000435 regulation of protein neddylation(GO:2000434) negative regulation of protein neddylation(GO:2000435)
0.0 0.3 GO:0051001 negative regulation of nitric-oxide synthase activity(GO:0051001)
0.0 0.5 GO:0071539 protein localization to centrosome(GO:0071539)
0.0 0.2 GO:0090110 cargo loading into COPII-coated vesicle(GO:0090110)
0.0 1.1 GO:0035914 skeletal muscle cell differentiation(GO:0035914)
0.0 0.5 GO:0006493 protein O-linked glycosylation(GO:0006493)
0.0 0.3 GO:0007026 negative regulation of microtubule depolymerization(GO:0007026)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 2.5 GO:0043512 inhibin A complex(GO:0043512)
0.2 0.7 GO:0099631 postsynaptic endocytic zone cytoplasmic component(GO:0099631)
0.2 0.8 GO:0097447 dendritic tree(GO:0097447)
0.1 0.6 GO:1990452 Parkin-FBXW7-Cul1 ubiquitin ligase complex(GO:1990452)
0.1 14.0 GO:0001725 stress fiber(GO:0001725) contractile actin filament bundle(GO:0097517)
0.1 0.9 GO:0097427 microtubule bundle(GO:0097427)
0.1 1.2 GO:0097449 dense core granule(GO:0031045) astrocyte projection(GO:0097449)
0.1 1.1 GO:0042101 T cell receptor complex(GO:0042101)
0.1 3.2 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.1 0.5 GO:0031313 extrinsic component of endosome membrane(GO:0031313)
0.1 0.5 GO:0033269 internode region of axon(GO:0033269)
0.1 0.5 GO:0036056 filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057)
0.0 0.3 GO:0097442 CA3 pyramidal cell dendrite(GO:0097442)
0.0 4.5 GO:0043195 terminal bouton(GO:0043195)
0.0 0.1 GO:0034751 aryl hydrocarbon receptor complex(GO:0034751)
0.0 0.4 GO:0005665 DNA-directed RNA polymerase II, core complex(GO:0005665)
0.0 0.2 GO:0030127 COPII vesicle coat(GO:0030127)
0.0 0.2 GO:0032580 Golgi cisterna membrane(GO:0032580)
0.0 1.2 GO:0008076 voltage-gated potassium channel complex(GO:0008076)
0.0 0.1 GO:0031362 anchored component of external side of plasma membrane(GO:0031362)
0.0 0.5 GO:0042734 presynaptic membrane(GO:0042734)
0.0 0.4 GO:0001917 photoreceptor inner segment(GO:0001917)
0.0 0.7 GO:0019005 SCF ubiquitin ligase complex(GO:0019005)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 2.5 GO:0070699 type II activin receptor binding(GO:0070699)
0.3 1.2 GO:0030348 syntaxin-3 binding(GO:0030348)
0.3 6.0 GO:0071855 neuropeptide receptor binding(GO:0071855)
0.2 1.2 GO:0005250 A-type (transient outward) potassium channel activity(GO:0005250)
0.2 0.6 GO:0016160 alpha-amylase activity(GO:0004556) amylase activity(GO:0016160)
0.2 0.6 GO:0050220 prostaglandin-E synthase activity(GO:0050220)
0.2 0.5 GO:0016262 protein N-acetylglucosaminyltransferase activity(GO:0016262)
0.1 0.8 GO:0046912 transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer(GO:0046912)
0.1 0.6 GO:0050816 phosphothreonine binding(GO:0050816)
0.1 2.4 GO:0005159 insulin-like growth factor receptor binding(GO:0005159)
0.1 0.3 GO:0008061 chitin binding(GO:0008061)
0.1 0.3 GO:0004609 phosphatidylserine decarboxylase activity(GO:0004609)
0.1 0.6 GO:0035312 5'-3' exodeoxyribonuclease activity(GO:0035312)
0.1 0.7 GO:0032050 clathrin heavy chain binding(GO:0032050)
0.0 0.3 GO:0003876 AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
0.0 0.1 GO:0051870 methotrexate binding(GO:0051870)
0.0 0.9 GO:0050321 tau-protein kinase activity(GO:0050321)
0.0 0.5 GO:0097109 neuroligin family protein binding(GO:0097109)
0.0 0.3 GO:0005519 cytoskeletal regulatory protein binding(GO:0005519)
0.0 0.8 GO:0030215 semaphorin receptor binding(GO:0030215)
0.0 0.5 GO:0005545 1-phosphatidylinositol binding(GO:0005545)
0.0 0.3 GO:0015093 ferrous iron transmembrane transporter activity(GO:0015093)
0.0 0.1 GO:0032896 palmitoyl-CoA 9-desaturase activity(GO:0032896)
0.0 0.1 GO:0035614 snRNA stem-loop binding(GO:0035614)
0.0 0.1 GO:0009378 four-way junction helicase activity(GO:0009378)
0.0 10.3 GO:0003779 actin binding(GO:0003779)
0.0 0.2 GO:0016308 1-phosphatidylinositol-4-phosphate 5-kinase activity(GO:0016308)
0.0 0.5 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.0 0.2 GO:0004806 triglyceride lipase activity(GO:0004806)
0.0 0.4 GO:0032794 GTPase activating protein binding(GO:0032794)
0.0 0.9 GO:0005200 structural constituent of cytoskeleton(GO:0005200)
0.0 0.1 GO:0002135 CTP binding(GO:0002135)
0.0 0.6 GO:0070412 R-SMAD binding(GO:0070412)
0.0 0.2 GO:0004000 adenosine deaminase activity(GO:0004000)
0.0 0.4 GO:0032183 SUMO binding(GO:0032183)
0.0 0.2 GO:0008308 voltage-gated anion channel activity(GO:0008308)
0.0 4.0 GO:0005096 GTPase activator activity(GO:0005096)
0.0 0.5 GO:0035035 histone acetyltransferase binding(GO:0035035)
0.0 0.1 GO:0005212 structural constituent of eye lens(GO:0005212)
0.0 0.2 GO:0017128 phospholipid scramblase activity(GO:0017128)
0.0 1.2 GO:0003705 transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0003705)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 2.0 PID_RHODOPSIN_PATHWAY Visual signal transduction: Rods
0.1 1.5 PID_S1P_S1P4_PATHWAY S1P4 pathway
0.1 2.5 PID_ALK1_PATHWAY ALK1 signaling events
0.0 1.3 PID_ARF_3PATHWAY Arf1 pathway
0.0 2.4 PID_AJDISS_2PATHWAY Posttranslational regulation of adherens junction stability and dissassembly
0.0 0.8 PID_MAPK_TRK_PATHWAY Trk receptor signaling mediated by the MAPK pathway
0.0 0.6 PID_IFNG_PATHWAY IFN-gamma pathway
0.0 0.9 PID_ERBB1_INTERNALIZATION_PATHWAY Internalization of ErbB1
0.0 0.6 PID_MYC_PATHWAY C-MYC pathway
0.0 1.2 PID_LKB1_PATHWAY LKB1 signaling events
0.0 0.8 PID_MYC_REPRESS_PATHWAY Validated targets of C-MYC transcriptional repression

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 2.5 REACTOME_GLYCOPROTEIN_HORMONES Genes involved in Glycoprotein hormones
0.6 15.6 REACTOME_DCC_MEDIATED_ATTRACTIVE_SIGNALING Genes involved in DCC mediated attractive signaling
0.2 2.4 REACTOME_REGULATION_OF_INSULIN_LIKE_GROWTH_FACTOR_IGF_ACTIVITY_BY_INSULIN_LIKE_GROWTH_FACTOR_BINDING_PROTEINS_IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.1 1.9 REACTOME_G_PROTEIN_ACTIVATION Genes involved in G-protein activation
0.1 4.5 REACTOME_PEPTIDE_LIGAND_BINDING_RECEPTORS Genes involved in Peptide ligand-binding receptors
0.0 0.8 REACTOME_SIGNALLING_TO_P38_VIA_RIT_AND_RIN Genes involved in Signalling to p38 via RIT and RIN
0.0 1.6 REACTOME_EGFR_DOWNREGULATION Genes involved in EGFR downregulation
0.0 0.4 REACTOME_COPI_MEDIATED_TRANSPORT Genes involved in COPI Mediated Transport
0.0 0.4 REACTOME_POST_CHAPERONIN_TUBULIN_FOLDING_PATHWAY Genes involved in Post-chaperonin tubulin folding pathway
0.0 1.6 REACTOME_G_ALPHA_I_SIGNALLING_EVENTS Genes involved in G alpha (i) signalling events
0.0 0.4 REACTOME_VIRAL_MESSENGER_RNA_SYNTHESIS Genes involved in Viral Messenger RNA Synthesis
0.0 0.3 REACTOME_PURINE_SALVAGE Genes involved in Purine salvage
0.0 0.1 REACTOME_THE_NLRP3_INFLAMMASOME Genes involved in The NLRP3 inflammasome
0.0 0.6 REACTOME_ASSOCIATION_OF_TRIC_CCT_WITH_TARGET_PROTEINS_DURING_BIOSYNTHESIS Genes involved in Association of TriC/CCT with target proteins during biosynthesis
0.0 0.2 REACTOME_ANTIGEN_PRESENTATION_FOLDING_ASSEMBLY_AND_PEPTIDE_LOADING_OF_CLASS_I_MHC Genes involved in Antigen Presentation: Folding, assembly and peptide loading of class I MHC
0.0 1.4 REACTOME_P75_NTR_RECEPTOR_MEDIATED_SIGNALLING Genes involved in p75 NTR receptor-mediated signalling
0.0 0.3 REACTOME_ENOS_ACTIVATION_AND_REGULATION Genes involved in eNOS activation and regulation
0.0 1.1 REACTOME_L1CAM_INTERACTIONS Genes involved in L1CAM interactions