• All motifs sorted by activity significance
• All samples sorted alphabetically
• Mean activities
• All promoters sorted by FOV

• Activities table
• Activity deltas table
• Regulatory interactions
• Motifs sorted by significance (text)
• Download the whole report

Motif ID: Hoxb5

Z-value: 0.625

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Top targets:

Promoter	Score	Refseq	Gene Symbol	Gene Name
chr1_-_56971762	4.146	ENSMUST00000114415.3	Satb2	special AT-rich sequence binding protein 2
chr5_+_125532377	3.977	ENSMUST00000031446.6	Tmem132b	transmembrane protein 132B
chr6_-_18514802	2.554	ENSMUST00000090601.5	Cttnbp2	cortactin binding protein 2
chr17_+_35076902	2.121	ENSMUST00000172494.1 ENSMUST00000172678.1 ENSMUST00000013910.4	Ly6g6e	lymphocyte antigen 6 complex, locus G6E
chr17_-_57087729	1.917	ENSMUST00000071135.5	Tubb4a	tubulin, beta 4A class IVA
chr2_+_158667119	1.844	ENSMUST00000045503.4	Ppp1r16b	protein phosphatase 1, regulatory (inhibitor) subunit 16B
chr17_+_35077080	1.733	ENSMUST00000172959.1	Ly6g6e	lymphocyte antigen 6 complex, locus G6E
chr3_-_103737995	1.716	ENSMUST00000029440.8	Olfml3	olfactomedin-like 3
chr12_-_78980758	1.593	ENSMUST00000174072.1	Tmem229b	transmembrane protein 229B
chr11_+_74619594	1.557	ENSMUST00000100866.2	E130309D14Rik	RIKEN cDNA E130309D14 gene
chr12_-_78983476	1.543	ENSMUST00000070174.7	Tmem229b	transmembrane protein 229B
chr2_+_85136355	1.521	ENSMUST00000057019.7	Aplnr	apelin receptor
chr10_-_63927434	1.360	ENSMUST00000079279.3	Gm10118	predicted gene 10118
chr9_-_35116804	1.346	ENSMUST00000034537.6	St3gal4	ST3 beta-galactoside alpha-2,3-sialyltransferase 4
chrX_-_165327376	1.281	ENSMUST00000058787.8	Glra2	glycine receptor, alpha 2 subunit
chr3_-_85722474	1.263	ENSMUST00000119077.1	Fam160a1	family with sequence similarity 160, member A1
chr11_-_96075655	1.219	ENSMUST00000090541.5	Atp5g1	ATP synthase, H+ transporting, mitochondrial F0 complex, subunit c1 (subunit 9)
chr11_-_96075581	1.179	ENSMUST00000107686.1 ENSMUST00000107684.1	Atp5g1	ATP synthase, H+ transporting, mitochondrial F0 complex, subunit c1 (subunit 9)
chr17_-_47691403	1.130	ENSMUST00000113299.1 ENSMUST00000152214.1	Gm21981 Prickle4	predicted gene 21981 prickle homolog 4 (Drosophila)
chr14_+_32159865	1.105	ENSMUST00000163336.1 ENSMUST00000169722.1 ENSMUST00000168385.1	Ncoa4	nuclear receptor coactivator 4
chr10_+_21882184	1.074	ENSMUST00000120509.1	Sgk1	serum/glucocorticoid regulated kinase 1
chr7_+_3390629	0.987	ENSMUST00000182222.1	Cacng8	calcium channel, voltage-dependent, gamma subunit 8
chr2_-_153225396	0.977	ENSMUST00000099194.2	Tspyl3	TSPY-like 3
chr8_-_85840877	0.937	ENSMUST00000034140.7	Itfg1	integrin alpha FG-GAP repeat containing 1
chr10_-_81014902	0.919	ENSMUST00000126317.1 ENSMUST00000092285.3 ENSMUST00000117805.1	Gng7	guanine nucleotide binding protein (G protein), gamma 7
chrX_-_10117597	0.915	ENSMUST00000115543.2 ENSMUST00000044789.3 ENSMUST00000115544.2	Srpx	sushi-repeat-containing protein
chr6_-_113501818	0.881	ENSMUST00000101059.1	Prrt3	proline-rich transmembrane protein 3
chr8_+_70594466	0.823	ENSMUST00000019283.9	Isyna1	myo-inositol 1-phosphate synthase A1
chr5_+_117133567	0.795	ENSMUST00000179276.1 ENSMUST00000092889.5 ENSMUST00000145640.1	Taok3	TAO kinase 3
chr3_-_89160155	0.781	ENSMUST00000029686.3	Hcn3	hyperpolarization-activated, cyclic nucleotide-gated K+ 3
chr6_+_121636173	0.778	ENSMUST00000032203.7	A2m	alpha-2-macroglobulin
chr17_+_47593516	0.777	ENSMUST00000182874.1	Ccnd3	cyclin D3
chr8_+_95081187	0.726	ENSMUST00000034239.7	Katnb1	katanin p80 (WD40-containing) subunit B 1
chr1_-_193370260	0.703	ENSMUST00000016323.4	Camk1g	calcium/calmodulin-dependent protein kinase I gamma
chr4_+_86053887	0.693	ENSMUST00000107178.2 ENSMUST00000048885.5 ENSMUST00000141889.1 ENSMUST00000120678.1	Adamtsl1	ADAMTS-like 1
chr14_-_41004517	0.683	ENSMUST00000153830.1	Fam213a	family with sequence similarity 213, member A
chr7_-_123500449	0.656	ENSMUST00000042470.7 ENSMUST00000128217.1	Zkscan2	zinc finger with KRAB and SCAN domains 2
chr1_-_193370225	0.618	ENSMUST00000169907.1	Camk1g	calcium/calmodulin-dependent protein kinase I gamma
chr17_+_47593444	0.607	ENSMUST00000182209.1	Ccnd3	cyclin D3
chr12_-_36042476	0.602	ENSMUST00000020896.8	Tspan13	tetraspanin 13
chr8_-_25597459	0.595	ENSMUST00000079160.6	Letm2	leucine zipper-EF-hand containing transmembrane protein 2
chr7_+_119895836	0.592	ENSMUST00000106518.1 ENSMUST00000054440.3	Lyrm1	LYR motif containing 1
chr16_+_17070220	0.563	ENSMUST00000141959.1	Ypel1	yippee-like 1 (Drosophila)
chrX_+_7723278	0.548	ENSMUST00000144148.1	Wdr45	WD repeat domain 45
chr9_-_35558522	0.546	ENSMUST00000034612.5	Ddx25	DEAD (Asp-Glu-Ala-Asp) box polypeptide 25
chr17_+_57105385	0.546	ENSMUST00000039490.7	Tnfsf9	tumor necrosis factor (ligand) superfamily, member 9
chr16_+_17070127	0.536	ENSMUST00000115729.1	Ypel1	yippee-like 1 (Drosophila)
chr7_+_19004047	0.535	ENSMUST00000053713.3	Irf2bp1	interferon regulatory factor 2 binding protein 1
chr15_-_28025834	0.525	ENSMUST00000090247.5	Trio	triple functional domain (PTPRF interacting)
chr6_+_86438360	0.510	ENSMUST00000050497.7	C87436	expressed sequence C87436
chr16_+_17070281	0.486	ENSMUST00000090199.3	Ypel1	yippee-like 1 (Drosophila)
chr2_-_167062607	0.485	ENSMUST00000128676.1	Znfx1	zinc finger, NFX1-type containing 1
chr7_-_133709051	0.463	ENSMUST00000124759.1 ENSMUST00000106144.1	Uros	uroporphyrinogen III synthase
chr8_+_123653903	0.453	ENSMUST00000045487.3	Rhou	ras homolog gene family, member U
chr19_-_45816007	0.443	ENSMUST00000079431.3 ENSMUST00000026247.6 ENSMUST00000162528.2	Kcnip2	Kv channel-interacting protein 2
chr18_-_16809233	0.415	ENSMUST00000025166.7	Cdh2	cadherin 2
chr10_-_127211528	0.405	ENSMUST00000013970.7	Pip4k2c	phosphatidylinositol-5-phosphate 4-kinase, type II, gamma
chr7_+_119896292	0.397	ENSMUST00000106517.1	Lyrm1	LYR motif containing 1
chr10_+_80300997	0.391	ENSMUST00000140828.1 ENSMUST00000138909.1	Apc2	adenomatosis polyposis coli 2
chr4_+_123233556	0.356	ENSMUST00000040821.4	Heyl	hairy/enhancer-of-split related with YRPW motif-like
chrX_+_7822289	0.350	ENSMUST00000009875.4	Kcnd1	potassium voltage-gated channel, Shal-related family, member 1
chr10_-_62143906	0.338	ENSMUST00000141724.1 ENSMUST00000150057.1	2010107G23Rik	RIKEN cDNA 2010107G23 gene
chr9_+_20581296	0.331	ENSMUST00000115557.2	Zfp846	zinc finger protein 846
chrX_+_20687954	0.323	ENSMUST00000115364.1	Cdk16	cyclin-dependent kinase 16
chr17_+_31386244	0.314	ENSMUST00000134525.1 ENSMUST00000127929.1	Pde9a	phosphodiesterase 9A
chrX_-_72656135	0.298	ENSMUST00000055966.6	Gabra3	gamma-aminobutyric acid (GABA) A receptor, subunit alpha 3
chr7_-_109083284	0.290	ENSMUST00000120876.1 ENSMUST00000055993.6	Ric3	resistance to inhibitors of cholinesterase 3 homolog (C. elegans)
chr2_+_152962485	0.276	ENSMUST00000099197.2 ENSMUST00000103155.3	Ttll9	tubulin tyrosine ligase-like family, member 9
chr6_+_141249161	0.261	ENSMUST00000043259.7	Pde3a	phosphodiesterase 3A, cGMP inhibited
chr5_+_143933059	0.252	ENSMUST00000166847.1	Rsph10b	radial spoke head 10 homolog B (Chlamydomonas)
chr7_-_133708958	0.249	ENSMUST00000106146.1	Uros	uroporphyrinogen III synthase
chr2_+_116067933	0.247	ENSMUST00000156095.1	G630016G05Rik	RIKEN cDNA G630016G05 gene
chr7_-_133709069	0.238	ENSMUST00000106145.3	Uros	uroporphyrinogen III synthase
chr5_-_103211251	0.225	ENSMUST00000060871.5 ENSMUST00000112846.1 ENSMUST00000170792.1 ENSMUST00000112847.2	Mapk10	mitogen-activated protein kinase 10
chr17_+_31386218	0.204	ENSMUST00000047168.5	Pde9a	phosphodiesterase 9A
chr14_+_55559993	0.192	ENSMUST00000117236.1	Dcaf11	DDB1 and CUL4 associated factor 11
chr4_-_108848619	0.158	ENSMUST00000164855.1	A730015C16Rik	RIKEN cDNA A730015C16 gene
chr13_+_93304066	0.147	ENSMUST00000109493.1	Homer1	homer homolog 1 (Drosophila)
chr14_+_55560010	0.143	ENSMUST00000147981.1 ENSMUST00000133256.1	Dcaf11	DDB1 and CUL4 associated factor 11
chr14_-_63543931	0.131	ENSMUST00000058679.5	Mtmr9	myotubularin related protein 9
chr3_+_89215170	0.122	ENSMUST00000029682.4	Thbs3	thrombospondin 3
chr7_-_100964371	0.111	ENSMUST00000060174.4	P2ry6	pyrimidinergic receptor P2Y, G-protein coupled, 6
chr17_+_47385386	0.106	ENSMUST00000024774.7 ENSMUST00000145462.1	Guca1b	guanylate cyclase activator 1B
chr17_+_94873986	0.081	ENSMUST00000108007.4	Gm20939	predicted gene, 20939
chr1_-_166409773	0.079	ENSMUST00000135673.1 ENSMUST00000079972.6 ENSMUST00000169324.1 ENSMUST00000111411.2 ENSMUST00000128861.1	Pogk	pogo transposable element with KRAB domain
chr11_+_4873951	0.057	ENSMUST00000038570.2	Nipsnap1	4-nitrophenylphosphatase domain and non-neuronal SNAP25-like protein homolog 1 (C. elegans)
chr8_+_123332676	0.046	ENSMUST00000010298.6	Spire2	spire homolog 2 (Drosophila)
chr7_-_127208423	0.042	ENSMUST00000120705.1	Tbc1d10b	TBC1 domain family, member 10b
chr18_+_74268251	0.040	ENSMUST00000097530.3	Mbd1	methyl-CpG binding domain protein 1
chr7_+_127841752	0.038	ENSMUST00000033075.7	Stx4a	syntaxin 4A (placental)
chr7_-_45466894	0.027	ENSMUST00000033093.8	Bax	BCL2-associated X protein
chr7_-_119896285	0.014	ENSMUST00000106519.1	Dcun1d3	DCN1, defective in cullin neddylation 1, domain containing 3 (S. cerevisiae)
chr11_+_97798995	0.012	ENSMUST00000143571.1	Lasp1	LIM and SH3 protein 1

Gene overrepresentation in biological_process category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.5	1.5	GO:0002030	inhibitory G-protein coupled receptor phosphorylation(GO:0002030)
0.4	1.8	GO:1903587	negative regulation of peptidyl-serine dephosphorylation(GO:1902309) regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis(GO:1903587)
0.3	0.9	GO:0060244	negative regulation of cell proliferation involved in contact inhibition(GO:0060244)
0.3	0.8	GO:0001869	regulation of complement activation, lectin pathway(GO:0001868) negative regulation of complement activation, lectin pathway(GO:0001869)
0.3	4.1	GO:0021902	commitment of neuronal cell to specific neuron type in forebrain(GO:0021902)
0.2	0.7	GO:0031117	positive regulation of microtubule depolymerization(GO:0031117)
0.2	0.9	GO:0006780	uroporphyrinogen III biosynthetic process(GO:0006780)
0.2	1.3	GO:0060012	synaptic transmission, glycinergic(GO:0060012)
0.1	3.9	GO:0022401	desensitization of G-protein coupled receptor protein signaling pathway(GO:0002029) negative adaptation of signaling pathway(GO:0022401)
0.1	3.0	GO:0031115	negative regulation of microtubule polymerization(GO:0031115)
0.1	0.9	GO:0007168	receptor guanylyl cyclase signaling pathway(GO:0007168)
0.1	0.5	GO:0045583	regulation of cytotoxic T cell differentiation(GO:0045583) positive regulation of cytotoxic T cell differentiation(GO:0045585)
0.1	2.4	GO:0015991	ATP hydrolysis coupled proton transport(GO:0015991)
0.1	0.4	GO:0045163	clustering of voltage-gated potassium channels(GO:0045163)
0.1	0.8	GO:0006020	inositol metabolic process(GO:0006020)
0.1	1.4	GO:0030213	hyaluronan biosynthetic process(GO:0030213)
0.1	0.4	GO:0072014	proximal tubule development(GO:0072014)
0.1	0.4	GO:1902897	regulation of postsynaptic density protein 95 clustering(GO:1902897)
0.1	0.3	GO:0060282	positive regulation of oocyte development(GO:0060282)
0.1	1.1	GO:0006622	protein targeting to lysosome(GO:0006622)
0.0	0.4	GO:2000786	positive regulation of autophagosome assembly(GO:2000786)
0.0	0.5	GO:0034497	protein localization to pre-autophagosomal structure(GO:0034497)
0.0	0.8	GO:0007095	mitotic G2 DNA damage checkpoint(GO:0007095)
0.0	0.2	GO:0007258	JUN phosphorylation(GO:0007258)
0.0	0.1	GO:0030321	transepithelial chloride transport(GO:0030321)
0.0	1.0	GO:2000311	regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity(GO:2000311)
0.0	0.5	GO:0046069	cGMP catabolic process(GO:0046069)
0.0	1.3	GO:0018279	protein N-linked glycosylation via asparagine(GO:0018279)
0.0	0.0	GO:0070649	formin-nucleated actin cable assembly(GO:0070649)
0.0	0.1	GO:0031282	regulation of guanylate cyclase activity(GO:0031282)
0.0	0.3	GO:0030252	growth hormone secretion(GO:0030252)
0.0	0.1	GO:0060346	bone trabecula formation(GO:0060346)
0.0	0.3	GO:0007271	synaptic transmission, cholinergic(GO:0007271)
0.0	0.1	GO:0048875	chemical homeostasis within a tissue(GO:0048875)
0.0	0.7	GO:0045670	regulation of osteoclast differentiation(GO:0045670)
0.0	0.3	GO:0007214	gamma-aminobutyric acid signaling pathway(GO:0007214)
0.0	0.5	GO:0016601	Rac protein signal transduction(GO:0016601)
0.0	0.5	GO:0010501	RNA secondary structure unwinding(GO:0010501)

Gene overrepresentation in cellular_component category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.2	1.9	GO:0033269	internode region of axon(GO:0033269)
0.2	2.4	GO:0000276	mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276)
0.2	0.8	GO:0044316	cone cell pedicle(GO:0044316)
0.1	1.1	GO:0044754	autolysosome(GO:0044754)
0.1	0.5	GO:0033391	chromatoid body(GO:0033391)
0.1	0.8	GO:0016342	catenin complex(GO:0016342)
0.0	4.1	GO:0000118	histone deacetylase complex(GO:0000118)
0.0	1.6	GO:0034707	chloride channel complex(GO:0034707)
0.0	0.5	GO:0034045	pre-autophagosomal structure membrane(GO:0034045)
0.0	1.0	GO:0032281	AMPA glutamate receptor complex(GO:0032281)
0.0	1.3	GO:0000307	cyclin-dependent protein kinase holoenzyme complex(GO:0000307)
0.0	1.3	GO:0005776	autophagosome(GO:0005776)
0.0	1.0	GO:0030496	midbody(GO:0030496)
0.0	0.9	GO:0005834	heterotrimeric G-protein complex(GO:0005834)
0.0	2.9	GO:0008021	synaptic vesicle(GO:0008021)

Gene overrepresentation in molecular_function category:

Log-likelihood per target	Total log-likelihood	Term	Description
1.3	3.9	GO:0030549	acetylcholine receptor activator activity(GO:0030549)
0.4	1.3	GO:0016934	extracellular-glycine-gated ion channel activity(GO:0016933) extracellular-glycine-gated chloride channel activity(GO:0016934)
0.3	1.3	GO:0003836	beta-galactoside (CMP) alpha-2,3-sialyltransferase activity(GO:0003836)
0.3	2.6	GO:0005519	cytoskeletal regulatory protein binding(GO:0005519)
0.3	0.8	GO:0019966	C-X-C chemokine binding(GO:0019958) interleukin-1 binding(GO:0019966) tumor necrosis factor binding(GO:0043120)
0.2	0.8	GO:0005222	intracellular cAMP activated cation channel activity(GO:0005222)
0.2	0.8	GO:0005250	A-type (transient outward) potassium channel activity(GO:0005250)
0.2	0.9	GO:0004852	uroporphyrinogen-III synthase activity(GO:0004852)
0.1	2.4	GO:0046933	proton-transporting ATP synthase activity, rotational mechanism(GO:0046933)
0.1	0.4	GO:0016309	1-phosphatidylinositol-5-phosphate 4-kinase activity(GO:0016309)
0.1	1.1	GO:0043423	3-phosphoinositide-dependent protein kinase binding(GO:0043423)
0.1	0.4	GO:0035939	microsatellite binding(GO:0035939)
0.1	0.7	GO:0008568	microtubule-severing ATPase activity(GO:0008568)
0.1	0.2	GO:0016909	JUN kinase activity(GO:0004705) SAP kinase activity(GO:0016909)
0.0	1.7	GO:0004693	cyclin-dependent protein serine/threonine kinase activity(GO:0004693)
0.0	0.1	GO:0030249	guanylate cyclase regulator activity(GO:0030249)
0.0	0.8	GO:0004709	MAP kinase kinase kinase activity(GO:0004709)
0.0	0.4	GO:0045294	alpha-catenin binding(GO:0045294)
0.0	1.1	GO:0004683	calmodulin-dependent protein kinase activity(GO:0004683)
0.0	0.5	GO:0047555	3',5'-cyclic-GMP phosphodiesterase activity(GO:0047555)
0.0	1.9	GO:0005200	structural constituent of cytoskeleton(GO:0005200)
0.0	0.5	GO:0005164	tumor necrosis factor receptor binding(GO:0005164)
0.0	1.8	GO:0019888	protein phosphatase regulator activity(GO:0019888)
0.0	0.5	GO:0080025	phosphatidylinositol-3,5-bisphosphate binding(GO:0080025)
0.0	0.3	GO:0004890	GABA-A receptor activity(GO:0004890)
0.0	0.1	GO:0045028	G-protein coupled nucleotide receptor activity(GO:0001608) G-protein coupled purinergic nucleotide receptor activity(GO:0045028)
0.0	0.3	GO:0033130	acetylcholine receptor binding(GO:0033130)
0.0	0.1	GO:0031802	type 5 metabotropic glutamate receptor binding(GO:0031802)
0.0	0.6	GO:0005246	calcium channel regulator activity(GO:0005246)
0.0	0.3	GO:0004115	3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)

Gene overrepresentation in C2:CP category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.0	1.4	PID_IL2_STAT5_PATHWAY	IL2 signaling events mediated by STAT5
0.0	0.8	PID_IL6_7_PATHWAY	IL6-mediated signaling events
0.0	1.3	PID_FOXO_PATHWAY	FoxO family signaling
0.0	1.1	PID_AR_PATHWAY	Coregulation of Androgen receptor activity
0.0	0.5	PID_NETRIN_PATHWAY	Netrin-mediated signaling events
0.0	0.4	PID_NCADHERIN_PATHWAY	N-cadherin signaling events

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	2.4	REACTOME_FORMATION_OF_ATP_BY_CHEMIOSMOTIC_COUPLING	Genes involved in Formation of ATP by chemiosmotic coupling
0.1	1.9	REACTOME_POST_CHAPERONIN_TUBULIN_FOLDING_PATHWAY	Genes involved in Post-chaperonin tubulin folding pathway
0.1	1.6	REACTOME_LIGAND_GATED_ION_CHANNEL_TRANSPORT	Genes involved in Ligand-gated ion channel transport
0.1	0.8	REACTOME_INTRINSIC_PATHWAY	Genes involved in Intrinsic Pathway
0.0	0.9	REACTOME_METABOLISM_OF_PORPHYRINS	Genes involved in Metabolism of porphyrins
0.0	0.8	REACTOME_CGMP_EFFECTS	Genes involved in cGMP effects
0.0	0.9	REACTOME_G_BETA_GAMMA_SIGNALLING_THROUGH_PLC_BETA	Genes involved in G beta:gamma signalling through PLC beta
0.0	1.2	REACTOME_G1_PHASE	Genes involved in G1 Phase
0.0	1.0	REACTOME_TRAFFICKING_OF_AMPA_RECEPTORS	Genes involved in Trafficking of AMPA receptors
0.0	0.5	REACTOME_DCC_MEDIATED_ATTRACTIVE_SIGNALING	Genes involved in DCC mediated attractive signaling
0.0	1.5	REACTOME_PEPTIDE_LIGAND_BINDING_RECEPTORS	Genes involved in Peptide ligand-binding receptors
0.0	1.1	REACTOME_POTASSIUM_CHANNELS	Genes involved in Potassium Channels
0.0	0.1	REACTOME_P2Y_RECEPTORS	Genes involved in P2Y receptors
0.0	0.4	REACTOME_ADHERENS_JUNCTIONS_INTERACTIONS	Genes involved in Adherens junctions interactions

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