Motif ID: Hoxc6

Z-value: 0.276


Transcription factors associated with Hoxc6:

Gene SymbolEntrez IDGene Name
Hoxc6 ENSMUSG00000001661.4 Hoxc6



Activity profile for motif Hoxc6.

activity profile for motif Hoxc6


Sorted Z-values histogram for motif Hoxc6

Sorted Z-values for motif Hoxc6



Network of associatons between targets according to the STRING database.



First level regulatory network of Hoxc6

PNG image of the network

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Top targets:


Showing 1 to 20 of 56 entries
PromoterScoreRefseqGene SymbolGene Name
chr5_+_17574268 1.244 ENSMUST00000030568.7
 Sema3c
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C
chr4_+_144893127 0.884 ENSMUST00000142808.1
 Dhrs3
dehydrogenase/reductase (SDR family) member 3
chr3_+_5218546 0.732 ENSMUST00000026284.6
 Zfhx4
zinc finger homeodomain 4
chr3_+_151437887 0.508 ENSMUST00000046977.7
 Eltd1
EGF, latrophilin seven transmembrane domain containing 1
chr3_+_5218516 0.480 ENSMUST00000175866.1
 Zfhx4
zinc finger homeodomain 4
chr10_-_100589205 0.379 ENSMUST00000054471.8
 4930430F08Rik
RIKEN cDNA 4930430F08 gene
chr3_+_66985680 0.352 ENSMUST00000065047.6
 Rsrc1
arginine/serine-rich coiled-coil 1
chrM_-_14060 0.324 ENSMUST00000082419.1
 mt-Nd6
mitochondrially encoded NADH dehydrogenase 6
chr3_+_5218589 0.298 ENSMUST00000177488.1
 Zfhx4
zinc finger homeodomain 4
chr6_-_65144908 0.289 ENSMUST00000031982.4
 Hpgds
hematopoietic prostaglandin D synthase
chr19_+_11469353 0.289 ENSMUST00000165310.1
 Ms4a6c
membrane-spanning 4-domains, subfamily A, member 6C
chrM_+_14138 0.275 ENSMUST00000082421.1
 mt-Cytb
mitochondrially encoded cytochrome b
chr10_-_53647080 0.240 ENSMUST00000169866.1
 Fam184a
family with sequence similarity 184, member A
chr3_+_66985700 0.234 ENSMUST00000046542.6
ENSMUST00000162693.1
 Rsrc1

arginine/serine-rich coiled-coil 1

chr15_-_50889691 0.224 ENSMUST00000165201.2
ENSMUST00000184458.1
 Trps1

trichorhinophalangeal syndrome I (human)

chr15_+_44619551 0.220 ENSMUST00000022964.7
 Ebag9
estrogen receptor-binding fragment-associated gene 9
chr10_-_58718210 0.217 ENSMUST00000169859.1
 Gm17542
predicted gene, 17542
chr7_-_115846080 0.211 ENSMUST00000166207.1
 Sox6
SRY-box containing gene 6
chr3_+_66985647 0.208 ENSMUST00000162362.1
ENSMUST00000065074.7
 Rsrc1

arginine/serine-rich coiled-coil 1

chr3_-_113574242 0.204 ENSMUST00000142505.2
 Amy1
amylase 1, salivary

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 13 of 13 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.2 1.2 GO:0003350 pulmonary myocardium development(GO:0003350)
0.1 0.9 GO:0042572 retinol metabolic process(GO:0042572)
0.0 0.8 GO:0046677 response to antibiotic(GO:0046677)
0.0 0.4 GO:1902043 positive regulation of extrinsic apoptotic signaling pathway via death domain receptors(GO:1902043)
0.1 0.3 GO:2000255 negative regulation of male germ cell proliferation(GO:2000255)
0.1 0.3 GO:0033762 response to glucagon(GO:0033762)
0.1 0.2 GO:0034035 sulfate assimilation(GO:0000103) purine ribonucleoside bisphosphate metabolic process(GO:0034035) 3'-phosphoadenosine 5'-phosphosulfate metabolic process(GO:0050427)
0.0 0.2 GO:0035887 aortic smooth muscle cell differentiation(GO:0035887)
0.0 0.2 GO:2000741 positive regulation of mesenchymal stem cell differentiation(GO:2000741)
0.0 0.2 GO:0045974 miRNA mediated inhibition of translation(GO:0035278) negative regulation of translation, ncRNA-mediated(GO:0040033) regulation of translation, ncRNA-mediated(GO:0045974)
0.0 0.1 GO:1903244 positive regulation of cardiac muscle adaptation(GO:0010615) positive regulation of cardiac muscle hypertrophy in response to stress(GO:1903244) regulation of connective tissue replacement(GO:1905203)
0.0 0.1 GO:0052695 cellular glucuronidation(GO:0052695)
0.0 0.1 GO:0089700 protein kinase D signaling(GO:0089700)

Gene overrepresentation in cellular_component category:

Showing 1 to 7 of 7 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 0.3 GO:0045275 respiratory chain complex III(GO:0045275)
0.0 0.2 GO:0005850 eukaryotic translation initiation factor 2 complex(GO:0005850)
0.0 0.2 GO:0035068 micro-ribonucleoprotein complex(GO:0035068)
0.0 0.2 GO:0071564 npBAF complex(GO:0071564)
0.0 0.1 GO:0031262 Ndc80 complex(GO:0031262)
0.0 0.1 GO:0033010 paranodal junction(GO:0033010)
0.0 0.1 GO:0005955 calcineurin complex(GO:0005955)

Gene overrepresentation in molecular_function category:

Showing 1 to 8 of 8 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 1.2 GO:0038191 neuropilin binding(GO:0038191)
0.1 0.9 GO:0052650 NADP-retinol dehydrogenase activity(GO:0052650)
0.0 0.5 GO:0050136 NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.1 0.3 GO:0004667 prostaglandin-D synthase activity(GO:0004667)
0.0 0.3 GO:0008121 ubiquinol-cytochrome-c reductase activity(GO:0008121) oxidoreductase activity, acting on diphenols and related substances as donors(GO:0016679) oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor(GO:0016681)
0.0 0.3 GO:0004190 aspartic-type endopeptidase activity(GO:0004190) aspartic-type peptidase activity(GO:0070001)
0.1 0.2 GO:0016160 alpha-amylase activity(GO:0004556) amylase activity(GO:0016160)
0.0 0.1 GO:0033192 calmodulin-dependent protein phosphatase activity(GO:0033192)

Gene overrepresentation in C2:CP category:

Showing 1 to 2 of 2 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 1.2 NABA_ECM_AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.0 0.9 PID_TAP63_PATHWAY Validated transcriptional targets of TAp63 isoforms

Gene overrepresentation in C2:CP:REACTOME category:

Showing 1 to 1 of 1 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 0.2 REACTOME_CYTOSOLIC_SULFONATION_OF_SMALL_MOLECULES Genes involved in Cytosolic sulfonation of small molecules