Motif ID: Hoxd1

Z-value: 0.648


Transcription factors associated with Hoxd1:

Gene SymbolEntrez IDGene Name
Hoxd1 ENSMUSG00000042448.4 Hoxd1



Activity profile for motif Hoxd1.

activity profile for motif Hoxd1


Sorted Z-values histogram for motif Hoxd1

Sorted Z-values for motif Hoxd1



Network of associatons between targets according to the STRING database.



First level regulatory network of Hoxd1

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr3_-_85722474 2.172 ENSMUST00000119077.1
Fam160a1
family with sequence similarity 160, member A1
chr2_+_116067213 1.982 ENSMUST00000152412.1
G630016G05Rik
RIKEN cDNA G630016G05 gene
chr2_+_150323702 1.977 ENSMUST00000133235.2
Gm10130
predicted gene 10130
chr2_-_20943413 1.767 ENSMUST00000140230.1
Arhgap21
Rho GTPase activating protein 21
chr5_-_62766153 1.760 ENSMUST00000076623.4
Arap2
ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2
chr17_-_45659312 1.691 ENSMUST00000120717.1
Capn11
calpain 11
chr5_+_134932351 1.562 ENSMUST00000047196.7
ENSMUST00000111221.2
ENSMUST00000111219.1
ENSMUST00000068617.5
ENSMUST00000111218.1
ENSMUST00000136246.1
Wbscr27





Williams Beuren syndrome chromosome region 27 (human)





chr6_+_149582012 1.316 ENSMUST00000144085.2
Gm21814
predicted gene, 21814
chr2_-_116067391 1.303 ENSMUST00000140185.1
2700033N17Rik
RIKEN cDNA 2700033N17 gene
chr15_-_8710734 1.283 ENSMUST00000005493.7
Slc1a3
solute carrier family 1 (glial high affinity glutamate transporter), member 3
chr17_+_88440711 1.281 ENSMUST00000112238.2
ENSMUST00000155640.1
Foxn2

forkhead box N2

chr17_-_36032682 1.210 ENSMUST00000102678.4
H2-T23
histocompatibility 2, T region locus 23
chr15_-_8710409 1.177 ENSMUST00000157065.1
Slc1a3
solute carrier family 1 (glial high affinity glutamate transporter), member 3
chr5_+_107497762 1.123 ENSMUST00000152474.1
ENSMUST00000060553.7
A830010M20Rik

RIKEN cDNA A830010M20 gene

chr2_+_3424123 1.031 ENSMUST00000061852.5
ENSMUST00000100463.3
ENSMUST00000102988.3
ENSMUST00000115066.1
Dclre1c



DNA cross-link repair 1C, PSO2 homolog (S. cerevisiae)



chr12_-_55014329 1.026 ENSMUST00000172875.1
Baz1a
bromodomain adjacent to zinc finger domain 1A
chr15_+_25773985 1.022 ENSMUST00000125667.1
Myo10
myosin X
chr13_-_105054895 0.994 ENSMUST00000063551.5
Rgs7bp
regulator of G-protein signalling 7 binding protein
chr15_+_98571004 0.964 ENSMUST00000023728.6
4930415O20Rik
RIKEN cDNA 4930415O20 gene
chr2_-_177267036 0.937 ENSMUST00000108963.1
Gm14409
predicted gene 14409
chr3_-_116712644 0.903 ENSMUST00000029569.2
Slc35a3
solute carrier family 35 (UDP-N-acetylglucosamine (UDP-GlcNAc) transporter), member 3
chrM_+_10167 0.895 ENSMUST00000082414.1
mt-Nd4
mitochondrially encoded NADH dehydrogenase 4
chr12_-_98577940 0.892 ENSMUST00000110113.1
Kcnk10
potassium channel, subfamily K, member 10
chr2_+_109917639 0.878 ENSMUST00000046548.7
ENSMUST00000111037.2
Lgr4

leucine-rich repeat-containing G protein-coupled receptor 4

chr5_-_123012874 0.857 ENSMUST00000172729.1
Kdm2b
lysine (K)-specific demethylase 2B
chr11_+_35121126 0.835 ENSMUST00000069837.3
Slit3
slit homolog 3 (Drosophila)
chr13_+_44121167 0.827 ENSMUST00000163056.1
ENSMUST00000159595.1
Gm5083

predicted gene 5083

chr5_+_107497718 0.817 ENSMUST00000112671.2
A830010M20Rik
RIKEN cDNA A830010M20 gene
chrM_+_9870 0.788 ENSMUST00000084013.1
mt-Nd4l
mitochondrially encoded NADH dehydrogenase 4L
chr2_+_69897255 0.754 ENSMUST00000131553.1
Ubr3
ubiquitin protein ligase E3 component n-recognin 3
chr5_-_70842617 0.739 ENSMUST00000031119.1
Gabrg1
gamma-aminobutyric acid (GABA) A receptor, subunit gamma 1
chr1_+_65186727 0.725 ENSMUST00000097707.4
ENSMUST00000081154.7
Pikfyve

phosphoinositide kinase, FYVE finger containing

chr5_-_106926245 0.717 ENSMUST00000117588.1
Hfm1
HFM1, ATP-dependent DNA helicase homolog (S. cerevisiae)
chr9_-_85749308 0.702 ENSMUST00000039213.8
Ibtk
inhibitor of Bruton agammaglobulinemia tyrosine kinase
chr2_+_119047129 0.701 ENSMUST00000153300.1
ENSMUST00000028799.5
Casc5

cancer susceptibility candidate 5

chr2_+_119047116 0.685 ENSMUST00000152380.1
ENSMUST00000099542.2
Casc5

cancer susceptibility candidate 5

chr8_-_122915987 0.683 ENSMUST00000098333.4
Ankrd11
ankyrin repeat domain 11
chrX_-_143933089 0.673 ENSMUST00000087313.3
Dcx
doublecortin
chr16_-_55934797 0.660 ENSMUST00000122280.1
ENSMUST00000121703.2
Cep97

centrosomal protein 97

chr13_-_67332525 0.659 ENSMUST00000168892.1
ENSMUST00000109735.2
Zfp595

zinc finger protein 595

chr8_-_41041828 0.648 ENSMUST00000051379.7
Mtus1
mitochondrial tumor suppressor 1
chrX_+_16619698 0.644 ENSMUST00000026013.5
Maoa
monoamine oxidase A
chr12_+_52699297 0.643 ENSMUST00000095737.3
Akap6
A kinase (PRKA) anchor protein 6
chr19_+_3323301 0.636 ENSMUST00000025835.4
Cpt1a
carnitine palmitoyltransferase 1a, liver
chr6_-_57535422 0.634 ENSMUST00000042766.3
Ppm1k
protein phosphatase 1K (PP2C domain containing)
chr1_-_24612700 0.631 ENSMUST00000088336.1
Gm10222
predicted gene 10222
chr1_+_139454747 0.621 ENSMUST00000053364.8
ENSMUST00000097554.3
Aspm

asp (abnormal spindle)-like, microcephaly associated (Drosophila)

chr9_-_123851855 0.613 ENSMUST00000184082.1
ENSMUST00000167595.2
Fyco1

FYVE and coiled-coil domain containing 1

chr16_-_16600533 0.610 ENSMUST00000159542.1
Fgd4
FYVE, RhoGEF and PH domain containing 4
chr2_+_121956651 0.603 ENSMUST00000110574.1
Ctdspl2
CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase like 2
chr10_-_120112946 0.597 ENSMUST00000020449.5
Helb
helicase (DNA) B
chr16_-_55934845 0.583 ENSMUST00000121129.1
ENSMUST00000023270.7
Cep97

centrosomal protein 97

chr7_+_130774069 0.578 ENSMUST00000048453.5
Btbd16
BTB (POZ) domain containing 16
chr4_+_147132038 0.574 ENSMUST00000084149.3
Gm13139
predicted gene 13139
chr14_+_26259109 0.574 ENSMUST00000174494.1
Duxbl3
double homeobox B-like 3
chr9_+_72958785 0.560 ENSMUST00000098567.2
ENSMUST00000034734.8
Dyx1c1

dyslexia susceptibility 1 candidate 1 homolog (human)

chr2_+_131491764 0.548 ENSMUST00000028806.5
ENSMUST00000110179.2
ENSMUST00000110189.2
ENSMUST00000110182.2
ENSMUST00000110183.2
ENSMUST00000110186.2
ENSMUST00000110188.1
Smox






spermine oxidase






chr4_-_132075250 0.526 ENSMUST00000105970.1
ENSMUST00000105975.1
Epb4.1

erythrocyte protein band 4.1

chr5_-_63968867 0.524 ENSMUST00000154169.1
Rell1
RELT-like 1
chr19_-_37330613 0.505 ENSMUST00000131070.1
Ide
insulin degrading enzyme
chr10_+_90071095 0.504 ENSMUST00000183109.1
Anks1b
ankyrin repeat and sterile alpha motif domain containing 1B
chr10_-_110000219 0.503 ENSMUST00000032719.7
Nav3
neuron navigator 3
chr7_+_127511976 0.498 ENSMUST00000098025.4
Srcap
Snf2-related CREBBP activator protein
chr6_+_72097561 0.494 ENSMUST00000069994.4
ENSMUST00000114112.1
St3gal5

ST3 beta-galactoside alpha-2,3-sialyltransferase 5

chr4_+_146610961 0.490 ENSMUST00000130825.1
Gm13248
predicted gene 13248
chr4_+_103143052 0.483 ENSMUST00000106855.1
Mier1
mesoderm induction early response 1 homolog (Xenopus laevis
chr6_+_34029421 0.470 ENSMUST00000070189.3
ENSMUST00000101564.2
Lrguk

leucine-rich repeats and guanylate kinase domain containing

chr1_-_172027269 0.465 ENSMUST00000027837.6
ENSMUST00000111264.1
Vangl2

vang-like 2 (van gogh, Drosophila)

chr9_-_15301555 0.449 ENSMUST00000034414.8
4931406C07Rik
RIKEN cDNA 4931406C07 gene
chr11_-_107337556 0.427 ENSMUST00000040380.6
Pitpnc1
phosphatidylinositol transfer protein, cytoplasmic 1
chr14_+_25980039 0.426 ENSMUST00000173155.1
Duxbl1
double homeobox B-like 1
chr9_-_107872403 0.418 ENSMUST00000183035.1
Rbm6
RNA binding motif protein 6
chr2_+_69897220 0.418 ENSMUST00000055758.9
ENSMUST00000112251.2
Ubr3

ubiquitin protein ligase E3 component n-recognin 3

chr3_-_41742471 0.417 ENSMUST00000026866.8
Sclt1
sodium channel and clathrin linker 1
chr1_-_33814516 0.415 ENSMUST00000044455.5
ENSMUST00000115167.1
Zfp451

zinc finger protein 451

chr19_+_55895508 0.413 ENSMUST00000111646.1
Tcf7l2
transcription factor 7 like 2, T cell specific, HMG box
chr16_+_11406618 0.404 ENSMUST00000122168.1
Snx29
sorting nexin 29
chr17_-_32822200 0.401 ENSMUST00000179695.1
Zfp799
zinc finger protein 799
chr14_+_62292475 0.391 ENSMUST00000166879.1
Rnaseh2b
ribonuclease H2, subunit B
chr14_+_26119811 0.390 ENSMUST00000173617.1
Duxbl2
doubl homeobox B-like 2
chr2_+_91257323 0.390 ENSMUST00000111349.2
ENSMUST00000131711.1
Pacsin3

protein kinase C and casein kinase substrate in neurons 3

chr2_+_121956411 0.374 ENSMUST00000110578.1
Ctdspl2
CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase like 2
chr4_-_147809788 0.363 ENSMUST00000105734.3
ENSMUST00000176201.1
Gm13157
Gm20707
predicted gene 13157
predicted gene 20707
chr19_+_8802486 0.361 ENSMUST00000172175.1
Zbtb3
zinc finger and BTB domain containing 3
chr12_-_84617326 0.359 ENSMUST00000021666.4
Abcd4
ATP-binding cassette, sub-family D (ALD), member 4
chr4_+_145585166 0.331 ENSMUST00000105739.1
ENSMUST00000119718.1
Gm13212

predicted gene 13212

chr7_+_29816061 0.322 ENSMUST00000032796.6
ENSMUST00000178162.1
Zfp790

zinc finger protein 790

chr8_-_105966038 0.316 ENSMUST00000116429.2
ENSMUST00000034370.9
Slc12a4

solute carrier family 12, member 4

chr11_+_60537978 0.310 ENSMUST00000044250.3
Alkbh5
alkB, alkylation repair homolog 5 (E. coli)
chr19_+_23723279 0.310 ENSMUST00000067077.1
Gm9938
predicted gene 9938
chrX_+_9885622 0.300 ENSMUST00000067529.2
ENSMUST00000086165.3
Sytl5

synaptotagmin-like 5

chr7_-_6730412 0.299 ENSMUST00000051209.4
Peg3
paternally expressed 3
chr17_-_32886083 0.292 ENSMUST00000178401.1
Zfp870
zinc finger protein 870
chr3_+_94837702 0.292 ENSMUST00000107266.1
ENSMUST00000042402.5
ENSMUST00000107269.1
Pogz


pogo transposable element with ZNF domain


chr2_+_170731807 0.290 ENSMUST00000029075.4
Dok5
docking protein 5
chr10_-_117148474 0.288 ENSMUST00000020381.3
Frs2
fibroblast growth factor receptor substrate 2
chr1_-_33814591 0.281 ENSMUST00000019861.6
Zfp451
zinc finger protein 451
chr14_+_48446128 0.279 ENSMUST00000124720.1
Tmem260
transmembrane protein 260
chr14_-_104522615 0.272 ENSMUST00000022716.2
Rnf219
ring finger protein 219
chr4_+_147492417 0.260 ENSMUST00000105721.2
Gm13152
predicted gene 13152
chr8_+_113635787 0.258 ENSMUST00000035777.8
Mon1b
MON1 homolog b (yeast)
chr14_-_75754475 0.254 ENSMUST00000049168.7
Cog3
component of oligomeric golgi complex 3
chr19_-_32196393 0.244 ENSMUST00000151822.1
Sgms1
sphingomyelin synthase 1
chr2_-_45117349 0.241 ENSMUST00000176438.2
Zeb2
zinc finger E-box binding homeobox 2
chrX_-_143933204 0.240 ENSMUST00000112851.1
ENSMUST00000112856.2
ENSMUST00000033642.3
Dcx


doublecortin


chr2_-_156392829 0.223 ENSMUST00000088578.2
2900097C17Rik
RIKEN cDNA 2900097C17 gene
chr18_-_60273267 0.222 ENSMUST00000090260.4
Gm4841
predicted gene 4841
chr8_+_113635550 0.216 ENSMUST00000179926.1
Mon1b
MON1 homolog b (yeast)
chr2_-_160619971 0.215 ENSMUST00000109473.1
Gm14221
predicted gene 14221
chr11_+_109543694 0.211 ENSMUST00000106696.1
Arsg
arylsulfatase G
chrX_-_75578188 0.210 ENSMUST00000033545.5
Rab39b
RAB39B, member RAS oncogene family
chr16_+_34690548 0.206 ENSMUST00000023532.6
Ccdc14
coiled-coil domain containing 14
chr17_+_34931253 0.205 ENSMUST00000007253.5
Neu1
neuraminidase 1
chr10_-_76110956 0.201 ENSMUST00000120757.1
Slc5a4b
solute carrier family 5 (neutral amino acid transporters, system A), member 4b
chr7_+_79273201 0.196 ENSMUST00000037315.6
Abhd2
abhydrolase domain containing 2
chr2_-_73580288 0.193 ENSMUST00000028515.3
Chrna1
cholinergic receptor, nicotinic, alpha polypeptide 1 (muscle)
chr18_+_37355271 0.190 ENSMUST00000051163.1
Pcdhb8
protocadherin beta 8
chr9_+_105395348 0.185 ENSMUST00000035181.3
Aste1
asteroid homolog 1 (Drosophila)
chr13_+_83732438 0.182 ENSMUST00000182701.1
C130071C03Rik
RIKEN cDNA C130071C03 gene
chr1_-_158356258 0.173 ENSMUST00000004133.8
Brinp2
bone morphogenic protein/retinoic acid inducible neural-specific 2
chr14_+_47298260 0.161 ENSMUST00000166743.1
Mapk1ip1l
mitogen-activated protein kinase 1 interacting protein 1-like
chr10_-_86011833 0.158 ENSMUST00000105304.1
ENSMUST00000061699.5
Bpifc

BPI fold containing family C

chr11_-_87108656 0.145 ENSMUST00000051395.8
Prr11
proline rich 11
chr9_-_105395237 0.133 ENSMUST00000140851.1
Nek11
NIMA (never in mitosis gene a)-related expressed kinase 11
chr5_+_145204523 0.129 ENSMUST00000085671.3
ENSMUST00000031601.7
Zkscan5

zinc finger with KRAB and SCAN domains 5

chr7_+_128744870 0.123 ENSMUST00000042942.8
Sec23ip
Sec23 interacting protein
chr9_-_55919605 0.122 ENSMUST00000037408.8
Scaper
S phase cyclin A-associated protein in the ER
chr4_+_140700487 0.117 ENSMUST00000071169.2
Rcc2
regulator of chromosome condensation 2
chr13_-_56895737 0.112 ENSMUST00000022023.6
ENSMUST00000109871.1
Trpc7

transient receptor potential cation channel, subfamily C, member 7

chr18_+_31609512 0.107 ENSMUST00000164667.1
B930094E09Rik
RIKEN cDNA B930094E09 gene
chr4_+_134930898 0.106 ENSMUST00000030622.2
Syf2
SYF2 homolog, RNA splicing factor (S. cerevisiae)
chr9_-_119341390 0.102 ENSMUST00000139870.1
Myd88
myeloid differentiation primary response gene 88
chr3_+_94837533 0.098 ENSMUST00000107270.2
Pogz
pogo transposable element with ZNF domain
chr2_-_150255591 0.095 ENSMUST00000063463.5
Gm21994
predicted gene 21994
chr12_+_80644212 0.085 ENSMUST00000085245.5
Slc39a9
solute carrier family 39 (zinc transporter), member 9
chr18_-_61707583 0.081 ENSMUST00000025472.1
Pcyox1l
prenylcysteine oxidase 1 like
chr10_+_75037066 0.079 ENSMUST00000147802.1
ENSMUST00000020391.5
Rab36

RAB36, member RAS oncogene family

chr12_-_87388317 0.078 ENSMUST00000021424.4
Sptlc2
serine palmitoyltransferase, long chain base subunit 2
chr11_-_45955183 0.072 ENSMUST00000109254.1
Thg1l
tRNA-histidine guanylyltransferase 1-like (S. cerevisiae)
chr16_+_18836573 0.067 ENSMUST00000055413.6
2510002D24Rik
RIKEN cDNA 2510002D24 gene
chr5_+_29195983 0.062 ENSMUST00000160888.1
ENSMUST00000159272.1
ENSMUST00000001247.5
ENSMUST00000161398.1
ENSMUST00000160246.1
Rnf32




ring finger protein 32




chrX_-_160138375 0.061 ENSMUST00000033662.8
Pdha1
pyruvate dehydrogenase E1 alpha 1
chrX_+_107255878 0.055 ENSMUST00000101294.2
ENSMUST00000118820.1
ENSMUST00000120971.1
Gpr174


G protein-coupled receptor 174


chr12_+_16653470 0.054 ENSMUST00000111064.1
Ntsr2
neurotensin receptor 2
chr1_-_185329331 0.044 ENSMUST00000027921.4
ENSMUST00000110975.1
ENSMUST00000110974.3
Iars2


isoleucine-tRNA synthetase 2, mitochondrial


chr16_+_65520503 0.035 ENSMUST00000176330.1
ENSMUST00000004964.8
ENSMUST00000176038.1
Pou1f1


POU domain, class 1, transcription factor 1


chr18_-_24603464 0.033 ENSMUST00000154205.1
Slc39a6
solute carrier family 39 (metal ion transporter), member 6
chr2_-_84715160 0.030 ENSMUST00000035840.5
Zdhhc5
zinc finger, DHHC domain containing 5
chr11_-_45955465 0.025 ENSMUST00000011398.6
Thg1l
tRNA-histidine guanylyltransferase 1-like (S. cerevisiae)
chr12_+_72441933 0.022 ENSMUST00000161284.1
Lrrc9
leucine rich repeat containing 9
chr16_+_52031549 0.018 ENSMUST00000114471.1
Cblb
Casitas B-lineage lymphoma b
chr17_+_36837123 0.011 ENSMUST00000179968.1
ENSMUST00000130367.1
ENSMUST00000130801.1
ENSMUST00000144182.1
ENSMUST00000123715.1
ENSMUST00000053434.8
Trim26





tripartite motif-containing 26





chr8_+_72219726 0.006 ENSMUST00000003123.8
Fam32a
family with sequence similarity 32, member A
chr12_+_72441852 0.002 ENSMUST00000162159.1
Lrrc9
leucine rich repeat containing 9

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 2.5 GO:0043490 malate-aspartate shuttle(GO:0043490)
0.4 1.2 GO:2000564 antigen processing and presentation of endogenous peptide antigen via MHC class Ib via ER pathway(GO:0002488) antigen processing and presentation of endogenous peptide antigen via MHC class Ib via ER pathway, TAP-dependent(GO:0002489) CD8-positive, alpha-beta T cell proliferation(GO:0035740) regulation of CD8-positive, alpha-beta T cell proliferation(GO:2000564) positive regulation of CD8-positive, alpha-beta T cell activation(GO:2001187)
0.4 1.8 GO:0051684 maintenance of Golgi location(GO:0051684)
0.3 1.2 GO:0071596 ubiquitin-dependent protein catabolic process via the N-end rule pathway(GO:0071596)
0.3 0.9 GO:0072204 cell-cell signaling involved in kidney development(GO:0060995) Wnt signaling pathway involved in kidney development(GO:0061289) canonical Wnt signaling pathway involved in metanephric kidney development(GO:0061290) cell-cell signaling involved in metanephros development(GO:0072204)
0.2 0.7 GO:2000616 negative regulation of histone H3-K9 acetylation(GO:2000616)
0.2 0.9 GO:0015788 UDP-N-acetylglucosamine transport(GO:0015788)
0.2 0.9 GO:0021993 initiation of neural tube closure(GO:0021993)
0.2 0.6 GO:0042420 dopamine catabolic process(GO:0042420)
0.2 0.6 GO:0060316 positive regulation of ryanodine-sensitive calcium-release channel activity(GO:0060316)
0.2 0.5 GO:0019085 early viral transcription(GO:0019085)
0.2 0.6 GO:0051661 maintenance of centrosome location(GO:0051661)
0.2 0.5 GO:0060489 orthogonal dichotomous subdivision of terminal units involved in lung branching morphogenesis(GO:0060488) planar dichotomous subdivision of terminal units involved in lung branching morphogenesis(GO:0060489) lateral sprouting involved in lung morphogenesis(GO:0060490)
0.1 0.6 GO:0006269 DNA replication, synthesis of RNA primer(GO:0006269)
0.1 0.8 GO:0070100 negative regulation of chemokine-mediated signaling pathway(GO:0070100)
0.1 1.0 GO:0031848 protection from non-homologous end joining at telomere(GO:0031848)
0.1 0.6 GO:0072383 plus-end-directed vesicle transport along microtubule(GO:0072383) plus-end-directed organelle transport along microtubule(GO:0072386)
0.1 0.5 GO:0046208 spermine catabolic process(GO:0046208)
0.1 1.2 GO:1902018 regulation of mitotic spindle assembly(GO:1901673) negative regulation of cilium assembly(GO:1902018)
0.1 0.9 GO:0030322 stabilization of membrane potential(GO:0030322)
0.1 0.3 GO:0035553 oxidative single-stranded RNA demethylation(GO:0035553)
0.1 0.5 GO:0010992 ubiquitin homeostasis(GO:0010992)
0.1 0.3 GO:0046619 optic placode formation involved in camera-type eye formation(GO:0046619)
0.1 0.4 GO:0045162 clustering of voltage-gated sodium channels(GO:0045162)
0.1 0.6 GO:0030035 microspike assembly(GO:0030035)
0.1 0.9 GO:0048672 positive regulation of collateral sprouting(GO:0048672)
0.1 0.4 GO:0009235 cobalamin metabolic process(GO:0009235)
0.1 0.6 GO:0032000 positive regulation of fatty acid beta-oxidation(GO:0032000)
0.1 0.9 GO:0006120 mitochondrial electron transport, NADH to ubiquinone(GO:0006120)
0.1 0.4 GO:0048625 myoblast fate commitment(GO:0048625)
0.1 0.6 GO:0036159 outer dynein arm assembly(GO:0036158) inner dynein arm assembly(GO:0036159)
0.0 0.5 GO:0000712 resolution of meiotic recombination intermediates(GO:0000712)
0.0 0.5 GO:1900383 regulation of synaptic plasticity by receptor localization to synapse(GO:1900383)
0.0 0.2 GO:0006689 ganglioside catabolic process(GO:0006689) oligosaccharide catabolic process(GO:0009313)
0.0 0.2 GO:1903056 positive regulation of lens fiber cell differentiation(GO:1902748) regulation of melanosome organization(GO:1903056)
0.0 0.2 GO:1904659 glucose transmembrane transport(GO:1904659)
0.0 1.0 GO:0046827 positive regulation of protein export from nucleus(GO:0046827)
0.0 0.3 GO:0006686 sphingomyelin biosynthetic process(GO:0006686)
0.0 0.1 GO:2000338 positive regulation of interleukin-23 production(GO:0032747) chemokine (C-X-C motif) ligand 1 production(GO:0072566) regulation of chemokine (C-X-C motif) ligand 1 production(GO:2000338)
0.0 0.2 GO:0048630 skeletal muscle tissue growth(GO:0048630)
0.0 0.7 GO:0032288 myelin assembly(GO:0032288)
0.0 0.4 GO:0031937 positive regulation of chromatin silencing(GO:0031937)
0.0 0.1 GO:0030327 prenylated protein catabolic process(GO:0030327)
0.0 0.7 GO:0007214 gamma-aminobutyric acid signaling pathway(GO:0007214)
0.0 0.4 GO:0051382 kinetochore assembly(GO:0051382)
0.0 0.6 GO:0010758 regulation of macrophage chemotaxis(GO:0010758)
0.0 0.1 GO:0051987 positive regulation of attachment of spindle microtubules to kinetochore(GO:0051987)
0.0 0.2 GO:0071539 protein localization to centrosome(GO:0071539)
0.0 0.8 GO:0042773 ATP synthesis coupled electron transport(GO:0042773)
0.0 0.3 GO:0051386 regulation of neurotrophin TRK receptor signaling pathway(GO:0051386)
0.0 0.4 GO:2000001 regulation of DNA damage checkpoint(GO:2000001)
0.0 0.4 GO:0051044 positive regulation of membrane protein ectodomain proteolysis(GO:0051044)
0.0 1.3 GO:0035914 skeletal muscle cell differentiation(GO:0035914)
0.0 0.7 GO:0060325 face morphogenesis(GO:0060325)
0.0 0.2 GO:0032570 response to progesterone(GO:0032570)
0.0 0.0 GO:0006428 isoleucyl-tRNA aminoacylation(GO:0006428)
0.0 0.5 GO:0035082 axoneme assembly(GO:0035082)
0.0 1.0 GO:0051489 regulation of filopodium assembly(GO:0051489)
0.0 0.1 GO:0001675 acrosome assembly(GO:0001675)
0.0 0.0 GO:0060126 somatotropin secreting cell differentiation(GO:0060126)
0.0 0.3 GO:0048026 positive regulation of mRNA splicing, via spliceosome(GO:0048026)
0.0 0.1 GO:0061732 mitochondrial acetyl-CoA biosynthetic process from pyruvate(GO:0061732)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.0 GO:0008623 CHRAC(GO:0008623)
0.1 0.6 GO:0036449 microtubule minus-end(GO:0036449)
0.1 0.6 GO:0005658 alpha DNA polymerase:primase complex(GO:0005658)
0.1 0.5 GO:0060187 cell pole(GO:0060187)
0.1 1.2 GO:0042612 MHC class I protein complex(GO:0042612)
0.1 1.0 GO:0070419 nonhomologous end joining complex(GO:0070419)
0.1 0.4 GO:0032299 ribonuclease H2 complex(GO:0032299)
0.1 0.5 GO:0002177 manchette(GO:0002177)
0.0 0.4 GO:0070369 beta-catenin-TCF7L2 complex(GO:0070369)
0.0 0.7 GO:0032593 insulin-responsive compartment(GO:0032593)
0.0 0.4 GO:0071439 clathrin complex(GO:0071439)
0.0 0.5 GO:0031597 cytosolic proteasome complex(GO:0031597)
0.0 0.6 GO:0005640 nuclear outer membrane(GO:0005640)
0.0 0.2 GO:0097524 sperm plasma membrane(GO:0097524)
0.0 0.2 GO:0000138 Golgi trans cisterna(GO:0000138)
0.0 0.6 GO:0031307 integral component of mitochondrial outer membrane(GO:0031307)
0.0 1.7 GO:0001669 acrosomal vesicle(GO:0001669)
0.0 0.7 GO:0034707 chloride channel complex(GO:0034707)
0.0 0.2 GO:0005892 acetylcholine-gated channel complex(GO:0005892)
0.0 1.0 GO:0016459 myosin complex(GO:0016459)
0.0 0.3 GO:0017119 Golgi transport complex(GO:0017119)
0.0 0.8 GO:0045271 mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
0.0 0.1 GO:0017059 serine C-palmitoyltransferase complex(GO:0017059) endoplasmic reticulum palmitoyltransferase complex(GO:0031211)
0.0 0.9 GO:0031519 PcG protein complex(GO:0031519)
0.0 0.1 GO:0071014 post-mRNA release spliceosomal complex(GO:0071014)
0.0 0.1 GO:0045254 pyruvate dehydrogenase complex(GO:0045254)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 2.5 GO:0015501 glutamate:sodium symporter activity(GO:0015501)
0.2 0.5 GO:0046592 polyamine oxidase activity(GO:0046592) spermine:oxygen oxidoreductase (spermidine-forming) activity(GO:0052901)
0.2 0.7 GO:0030292 protein tyrosine kinase inhibitor activity(GO:0030292)
0.2 0.6 GO:0051378 primary amine oxidase activity(GO:0008131) serotonin binding(GO:0051378)
0.2 1.2 GO:0046703 natural killer cell lectin-like receptor binding(GO:0046703)
0.1 0.6 GO:0004095 carnitine O-palmitoyltransferase activity(GO:0004095) O-palmitoyltransferase activity(GO:0016416)
0.1 0.6 GO:0017116 single-stranded DNA-dependent ATP-dependent DNA helicase activity(GO:0017116)
0.1 1.0 GO:0035312 5'-3' exodeoxyribonuclease activity(GO:0035312)
0.1 0.8 GO:0048495 Roundabout binding(GO:0048495)
0.1 0.7 GO:0061665 SUMO ligase activity(GO:0061665)
0.1 0.7 GO:0016308 1-phosphatidylinositol-4-phosphate 5-kinase activity(GO:0016308)
0.1 1.7 GO:0004198 calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.1 0.9 GO:0022841 potassium ion leak channel activity(GO:0022841)
0.1 0.3 GO:0035515 oxidative RNA demethylase activity(GO:0035515)
0.1 0.9 GO:0016500 protein-hormone receptor activity(GO:0016500)
0.1 0.5 GO:0043559 insulin binding(GO:0043559)
0.1 1.7 GO:0050136 NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.1 0.4 GO:0004523 RNA-DNA hybrid ribonuclease activity(GO:0004523)
0.0 0.6 GO:0043495 protein anchor(GO:0043495)
0.0 0.2 GO:0033188 sphingomyelin synthase activity(GO:0033188) ceramide cholinephosphotransferase activity(GO:0047493)
0.0 1.1 GO:0005402 cation:sugar symporter activity(GO:0005402)
0.0 0.3 GO:0015379 potassium:chloride symporter activity(GO:0015379) potassium ion symporter activity(GO:0022820)
0.0 0.9 GO:0051864 histone demethylase activity (H3-K36 specific)(GO:0051864)
0.0 0.4 GO:0008526 phosphatidylinositol transporter activity(GO:0008526)
0.0 0.7 GO:0050811 GABA-A receptor activity(GO:0004890) GABA receptor binding(GO:0050811)
0.0 1.8 GO:0005547 phosphatidylinositol-3,4,5-trisphosphate binding(GO:0005547)
0.0 0.1 GO:0008192 RNA guanylyltransferase activity(GO:0008192)
0.0 0.3 GO:0005068 transmembrane receptor protein tyrosine kinase adaptor activity(GO:0005068) neurotrophin TRKA receptor binding(GO:0005168)
0.0 0.4 GO:0019855 calcium channel inhibitor activity(GO:0019855)
0.0 0.1 GO:0004758 serine C-palmitoyltransferase activity(GO:0004758) C-palmitoyltransferase activity(GO:0016454)
0.0 0.1 GO:0070976 TIR domain binding(GO:0070976)
0.0 0.6 GO:0044183 protein binding involved in protein folding(GO:0044183)
0.0 0.4 GO:0070016 gamma-catenin binding(GO:0045295) armadillo repeat domain binding(GO:0070016)
0.0 0.2 GO:0022848 acetylcholine-gated cation channel activity(GO:0022848)
0.0 1.0 GO:0030507 spectrin binding(GO:0030507)
0.0 0.2 GO:0047372 acylglycerol lipase activity(GO:0047372)
0.0 0.2 GO:0008484 sulfuric ester hydrolase activity(GO:0008484)
0.0 0.0 GO:0004822 isoleucine-tRNA ligase activity(GO:0004822)
0.0 0.1 GO:0034604 pyruvate dehydrogenase activity(GO:0004738) pyruvate dehydrogenase [NAD(P)+] activity(GO:0034603) pyruvate dehydrogenase (NAD+) activity(GO:0034604)
0.0 0.5 GO:0004407 histone deacetylase activity(GO:0004407)
0.0 0.1 GO:0016670 oxidoreductase activity, acting on a sulfur group of donors, oxygen as acceptor(GO:0016670)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 1.8 PID_ARF6_PATHWAY Arf6 signaling events
0.0 1.0 PID_DNA_PK_PATHWAY DNA-PK pathway in nonhomologous end joining
0.0 1.0 PID_NETRIN_PATHWAY Netrin-mediated signaling events
0.0 0.9 PID_LIS1_PATHWAY Lissencephaly gene (LIS1) in neuronal migration and development
0.0 0.6 PID_RET_PATHWAY Signaling events regulated by Ret tyrosine kinase
0.0 0.6 PID_HNF3B_PATHWAY FOXA2 and FOXA3 transcription factor networks
0.0 0.7 PID_BCR_5PATHWAY BCR signaling pathway

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.9 REACTOME_TANDEM_PORE_DOMAIN_POTASSIUM_CHANNELS Genes involved in Tandem pore domain potassium channels
0.1 0.6 REACTOME_NOREPINEPHRINE_NEUROTRANSMITTER_RELEASE_CYCLE Genes involved in Norepinephrine Neurotransmitter Release Cycle
0.0 0.7 REACTOME_SYNTHESIS_OF_PIPS_AT_THE_EARLY_ENDOSOME_MEMBRANE Genes involved in Synthesis of PIPs at the early endosome membrane
0.0 2.1 REACTOME_AMINO_ACID_AND_OLIGOPEPTIDE_SLC_TRANSPORTERS Genes involved in Amino acid and oligopeptide SLC transporters
0.0 0.5 REACTOME_METABOLISM_OF_POLYAMINES Genes involved in Metabolism of polyamines
0.0 2.0 REACTOME_NETRIN1_SIGNALING Genes involved in Netrin-1 signaling
0.0 0.6 REACTOME_ACTIVATED_AMPK_STIMULATES_FATTY_ACID_OXIDATION_IN_MUSCLE Genes involved in Activated AMPK stimulates fatty-acid oxidation in muscle
0.0 0.2 REACTOME_THE_ACTIVATION_OF_ARYLSULFATASES Genes involved in The activation of arylsulfatases
0.0 1.4 REACTOME_DEPOSITION_OF_NEW_CENPA_CONTAINING_NUCLEOSOMES_AT_THE_CENTROMERE Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere
0.0 0.2 REACTOME_PRESYNAPTIC_NICOTINIC_ACETYLCHOLINE_RECEPTORS Genes involved in Presynaptic nicotinic acetylcholine receptors
0.0 0.9 REACTOME_TRANSPORT_OF_VITAMINS_NUCLEOSIDES_AND_RELATED_MOLECULES Genes involved in Transport of vitamins, nucleosides, and related molecules
0.0 2.3 REACTOME_SIGNALING_BY_RHO_GTPASES Genes involved in Signaling by Rho GTPases
0.0 0.1 REACTOME_TRAF6_MEDIATED_IRF7_ACTIVATION_IN_TLR7_8_OR_9_SIGNALING Genes involved in TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling
0.0 0.3 REACTOME_PROLONGED_ERK_ACTIVATION_EVENTS Genes involved in Prolonged ERK activation events