Motif ID: Hoxd10

Z-value: 0.344


Transcription factors associated with Hoxd10:

Gene SymbolEntrez IDGene Name
Hoxd10 ENSMUSG00000050368.3 Hoxd10



Activity profile for motif Hoxd10.

activity profile for motif Hoxd10


Sorted Z-values histogram for motif Hoxd10

Sorted Z-values for motif Hoxd10



Network of associatons between targets according to the STRING database.



First level regulatory network of Hoxd10

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.
View svg image
View png image

Top targets:


Showing 1 to 20 of 39 entries
PromoterScoreRefseqGene SymbolGene Name
chr9_+_27790947 3.058 ENSMUST00000115243.2
 Opcml
opioid binding protein/cell adhesion molecule-like
chr8_-_84773381 2.231 ENSMUST00000109764.1
 Nfix
nuclear factor I/X
chr4_+_102254993 1.289 ENSMUST00000106908.2
 Pde4b
phosphodiesterase 4B, cAMP specific
chr3_+_86084434 1.258 ENSMUST00000107664.2
 Sh3d19
SH3 domain protein D19
chr3_-_80802789 1.177 ENSMUST00000107745.1
ENSMUST00000075316.4
 Gria2

glutamate receptor, ionotropic, AMPA2 (alpha 2)

chr2_+_65620829 0.853 ENSMUST00000028377.7
 Scn2a1
sodium channel, voltage-gated, type II, alpha 1
chr1_-_152625212 0.840 ENSMUST00000027760.7
 Rgl1
ral guanine nucleotide dissociation stimulator,-like 1
chr17_-_78684262 0.752 ENSMUST00000145480.1
 Strn
striatin, calmodulin binding protein
chr9_-_90255927 0.742 ENSMUST00000144646.1
 Tbc1d2b
TBC1 domain family, member 2B
chr7_+_96210107 0.714 ENSMUST00000138760.1
 Tenm4
teneurin transmembrane protein 4
chrX_+_66653003 0.677 ENSMUST00000036043.4
 Slitrk2
SLIT and NTRK-like family, member 2
chr10_+_69534039 0.576 ENSMUST00000182557.1
 Ank3
ankyrin 3, epithelial
chr10_+_116177351 0.568 ENSMUST00000155606.1
ENSMUST00000128399.1
 Ptprr

protein tyrosine phosphatase, receptor type, R

chrX_-_70365052 0.550 ENSMUST00000101509.2
 Ids
iduronate 2-sulfatase
chr4_+_43401232 0.489 ENSMUST00000125399.1
 Rusc2
RUN and SH3 domain containing 2
chr11_-_110168073 0.479 ENSMUST00000044850.3
 Abca9
ATP-binding cassette, sub-family A (ABC1), member 9
chr2_+_106693185 0.449 ENSMUST00000111063.1
 Mpped2
metallophosphoesterase domain containing 2
chr15_+_9140527 0.448 ENSMUST00000090380.4
 Lmbrd2
LMBR1 domain containing 2
chr3_+_55461758 0.447 ENSMUST00000070418.4
 Dclk1
doublecortin-like kinase 1
chr13_+_40917626 0.340 ENSMUST00000067778.6
 Gcnt2
glucosaminyl (N-acetyl) transferase 2, I-branching enzyme

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 15 of 15 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 2.2 GO:0021684 cerebellar granular layer formation(GO:0021684) cerebellar granule cell differentiation(GO:0021707)
0.1 1.3 GO:1901898 negative regulation of relaxation of cardiac muscle(GO:1901898)
0.1 1.3 GO:0051044 positive regulation of membrane protein ectodomain proteolysis(GO:0051044)
0.0 1.2 GO:0035235 ionotropic glutamate receptor signaling pathway(GO:0035235)
0.2 0.7 GO:0032289 central nervous system myelin formation(GO:0032289) cardiac cell fate specification(GO:0060912)
0.1 0.6 GO:0038128 ERBB2 signaling pathway(GO:0038128)
0.1 0.6 GO:0010650 positive regulation of cell communication by electrical coupling(GO:0010650) positive regulation of membrane depolarization during cardiac muscle cell action potential(GO:1900827)
0.1 0.3 GO:0036438 maintenance of lens transparency(GO:0036438)
0.0 0.3 GO:0048341 paraxial mesoderm formation(GO:0048341)
0.1 0.2 GO:1903225 negative regulation of endodermal cell differentiation(GO:1903225)
0.1 0.2 GO:0001830 trophectodermal cell fate commitment(GO:0001830)
0.0 0.1 GO:0061010 gall bladder development(GO:0061010)
0.0 0.1 GO:0071918 urea transmembrane transport(GO:0071918)
0.0 0.1 GO:1905000 regulation of membrane repolarization during atrial cardiac muscle cell action potential(GO:1905000)
0.0 0.1 GO:1904884 telomerase catalytic core complex assembly(GO:1904868) regulation of telomerase catalytic core complex assembly(GO:1904882) positive regulation of telomerase catalytic core complex assembly(GO:1904884)

Gene overrepresentation in cellular_component category:

Showing 1 to 7 of 7 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 1.3 GO:0000930 gamma-tubulin complex(GO:0000930)
0.1 1.2 GO:0032279 asymmetric synapse(GO:0032279)
0.0 0.8 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.0 0.6 GO:0014731 spectrin-associated cytoskeleton(GO:0014731)
0.0 0.3 GO:0032584 growth cone membrane(GO:0032584)
0.1 0.2 GO:0005588 collagen type V trimer(GO:0005588)
0.0 0.1 GO:0031523 Myb complex(GO:0031523)

Gene overrepresentation in molecular_function category:

Showing 1 to 12 of 12 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 1.3 GO:0070064 proline-rich region binding(GO:0070064)
0.0 1.3 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
0.2 1.2 GO:0004971 AMPA glutamate receptor activity(GO:0004971)
0.1 0.8 GO:0008321 Ral guanyl-nucleotide exchange factor activity(GO:0008321)
0.0 0.8 GO:0070016 armadillo repeat domain binding(GO:0070016)
0.0 0.5 GO:0008484 sulfuric ester hydrolase activity(GO:0008484)
0.1 0.3 GO:0008109 N-acetyllactosaminide beta-1,6-N-acetylglucosaminyltransferase activity(GO:0008109)
0.1 0.3 GO:0008195 phosphatidate phosphatase activity(GO:0008195)
0.0 0.3 GO:0017160 Ral GTPase binding(GO:0017160)
0.0 0.1 GO:0034988 Fc-gamma receptor I complex binding(GO:0034988)
0.0 0.1 GO:0015265 urea channel activity(GO:0015265)
0.0 0.1 GO:0008301 DNA binding, bending(GO:0008301)

Gene overrepresentation in C2:CP category:

Showing 1 to 2 of 2 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 1.2 PID_NCADHERIN_PATHWAY N-cadherin signaling events
0.0 0.8 PID_ER_NONGENOMIC_PATHWAY Plasma membrane estrogen receptor signaling

Gene overrepresentation in C2:CP:REACTOME category:

Showing 1 to 8 of 8 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 1.3 REACTOME_DARPP_32_EVENTS Genes involved in DARPP-32 events
0.0 1.3 REACTOME_GOLGI_ASSOCIATED_VESICLE_BIOGENESIS Genes involved in Golgi Associated Vesicle Biogenesis
0.0 1.2 REACTOME_TRAFFICKING_OF_GLUR2_CONTAINING_AMPA_RECEPTORS Genes involved in Trafficking of GluR2-containing AMPA receptors
0.0 0.6 REACTOME_INTERACTION_BETWEEN_L1_AND_ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.0 0.5 REACTOME_CS_DS_DEGRADATION Genes involved in CS/DS degradation
0.0 0.5 REACTOME_ABCA_TRANSPORTERS_IN_LIPID_HOMEOSTASIS Genes involved in ABCA transporters in lipid homeostasis
0.0 0.3 REACTOME_SYNTHESIS_OF_PE Genes involved in Synthesis of PE
0.0 0.3 REACTOME_INSULIN_SYNTHESIS_AND_PROCESSING Genes involved in Insulin Synthesis and Processing