Motif ID: Hsf2

Z-value: 1.171


Transcription factors associated with Hsf2:

Gene SymbolEntrez IDGene Name
Hsf2 ENSMUSG00000019878.7 Hsf2

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Hsf2mm10_v2_chr10_+_57486354_574864140.764.0e-08Click!


Activity profile for motif Hsf2.

activity profile for motif Hsf2


Sorted Z-values histogram for motif Hsf2

Sorted Z-values for motif Hsf2



Network of associatons between targets according to the STRING database.



First level regulatory network of Hsf2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr10_-_92164666 7.095 ENSMUST00000183123.1
ENSMUST00000182033.1
Rmst

rhabdomyosarcoma 2 associated transcript (non-coding RNA)

chr1_-_138847579 5.661 ENSMUST00000093486.3
ENSMUST00000046870.6
Lhx9

LIM homeobox protein 9

chr7_-_4752972 4.643 ENSMUST00000183971.1
ENSMUST00000182173.1
ENSMUST00000182738.1
ENSMUST00000184143.1
ENSMUST00000182111.1
ENSMUST00000182048.1
ENSMUST00000063324.7
Cox6b2






cytochrome c oxidase subunit VIb polypeptide 2






chr8_-_110168204 4.540 ENSMUST00000003754.6
Calb2
calbindin 2
chr1_+_138963709 4.538 ENSMUST00000168527.1
Dennd1b
DENN/MADD domain containing 1B
chr13_+_51645232 4.473 ENSMUST00000075853.5
Cks2
CDC28 protein kinase regulatory subunit 2
chr1_+_136467958 4.209 ENSMUST00000047817.6
Kif14
kinesin family member 14
chr4_-_53159885 4.179 ENSMUST00000030010.3
Abca1
ATP-binding cassette, sub-family A (ABC1), member 1
chr4_+_128883549 4.174 ENSMUST00000035667.8
Trim62
tripartite motif-containing 62
chr10_-_92165159 4.048 ENSMUST00000182567.1
ENSMUST00000181604.2
ENSMUST00000181213.1
Rmst


rhabdomyosarcoma 2 associated transcript (non-coding RNA)


chr17_-_70849644 4.000 ENSMUST00000134654.1
ENSMUST00000172229.1
ENSMUST00000127719.1
Tgif1


TGFB-induced factor homeobox 1


chr15_+_57694651 3.739 ENSMUST00000096430.4
Zhx2
zinc fingers and homeoboxes 2
chr3_+_94342092 3.607 ENSMUST00000029794.5
Them5
thioesterase superfamily member 5
chr17_-_70851189 3.602 ENSMUST00000059775.8
Tgif1
TGFB-induced factor homeobox 1
chr11_-_11970540 3.543 ENSMUST00000109653.1
Grb10
growth factor receptor bound protein 10
chr17_-_25797032 3.369 ENSMUST00000165838.1
ENSMUST00000002344.6
Metrn

meteorin, glial cell differentiation regulator

chr14_-_65833963 3.360 ENSMUST00000022613.9
Esco2
establishment of cohesion 1 homolog 2 (S. cerevisiae)
chr16_-_45844228 3.344 ENSMUST00000076333.5
Phldb2
pleckstrin homology-like domain, family B, member 2
chr11_-_100939357 3.320 ENSMUST00000092671.5
ENSMUST00000103114.1
Stat3

signal transducer and activator of transcription 3

chr2_+_152847961 3.306 ENSMUST00000164120.1
ENSMUST00000178997.1
ENSMUST00000109816.1
Tpx2


TPX2, microtubule-associated protein homolog (Xenopus laevis)


chr5_-_5514730 3.288 ENSMUST00000115445.1
ENSMUST00000179804.1
ENSMUST00000125110.1
ENSMUST00000115446.1
Cldn12



claudin 12



chr3_-_127780461 3.276 ENSMUST00000029662.5
ENSMUST00000161239.1
Alpk1

alpha-kinase 1

chr5_+_92683625 3.266 ENSMUST00000168878.1
Shroom3
shroom family member 3
chr5_+_17574726 3.227 ENSMUST00000169603.1
Sema3c
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C
chr11_+_43528759 3.218 ENSMUST00000050574.6
Ccnjl
cyclin J-like
chr16_-_45844303 3.169 ENSMUST00000036355.6
Phldb2
pleckstrin homology-like domain, family B, member 2
chr4_+_59626189 3.065 ENSMUST00000070150.4
ENSMUST00000052420.6
E130308A19Rik

RIKEN cDNA E130308A19 gene

chr2_+_152847993 3.061 ENSMUST00000028969.8
Tpx2
TPX2, microtubule-associated protein homolog (Xenopus laevis)
chr5_+_17574268 2.941 ENSMUST00000030568.7
Sema3c
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C
chr6_+_134929089 2.931 ENSMUST00000183867.1
ENSMUST00000184991.1
ENSMUST00000183905.1
RP23-45G16.5


RP23-45G16.5


chr9_-_72111172 2.897 ENSMUST00000183992.1
Tcf12
transcription factor 12
chr14_+_28504736 2.867 ENSMUST00000063465.4
Wnt5a
wingless-related MMTV integration site 5A
chr2_-_59948155 2.866 ENSMUST00000153136.1
Baz2b
bromodomain adjacent to zinc finger domain, 2B
chr18_+_50053282 2.857 ENSMUST00000148159.2
Tnfaip8
tumor necrosis factor, alpha-induced protein 8
chr1_-_119053619 2.803 ENSMUST00000062483.8
Gli2
GLI-Kruppel family member GLI2
chr2_-_28466266 2.802 ENSMUST00000127683.1
ENSMUST00000086370.4
1700007K13Rik

RIKEN cDNA 1700007K13 gene

chr9_+_72438519 2.789 ENSMUST00000184604.1
Mns1
meiosis-specific nuclear structural protein 1
chr14_-_48667508 2.780 ENSMUST00000144465.1
ENSMUST00000133479.1
ENSMUST00000119070.1
ENSMUST00000152018.1
Otx2



orthodenticle homolog 2 (Drosophila)



chr7_+_114745685 2.770 ENSMUST00000136645.1
ENSMUST00000169913.1
Insc

inscuteable homolog (Drosophila)

chr2_-_91931675 2.770 ENSMUST00000111309.1
Mdk
midkine
chr6_-_39206782 2.715 ENSMUST00000002305.8
Jhdm1d
jumonji C domain-containing histone demethylase 1 homolog D (S. cerevisiae)
chr7_+_127211608 2.710 ENSMUST00000032910.6
Mylpf
myosin light chain, phosphorylatable, fast skeletal muscle
chr5_-_5514873 2.640 ENSMUST00000060947.7
Cldn12
claudin 12
chr15_+_25773985 2.568 ENSMUST00000125667.1
Myo10
myosin X
chr9_+_65141154 2.555 ENSMUST00000034961.4
Igdcc3
immunoglobulin superfamily, DCC subclass, member 3
chr2_-_91931696 2.526 ENSMUST00000090602.5
Mdk
midkine
chrX_+_161717055 2.525 ENSMUST00000112338.1
Rai2
retinoic acid induced 2
chr7_-_118995211 2.521 ENSMUST00000008878.8
Gprc5b
G protein-coupled receptor, family C, group 5, member B
chr2_-_26503814 2.511 ENSMUST00000028288.4
Notch1
notch 1
chr11_+_34314757 2.448 ENSMUST00000165963.1
ENSMUST00000093192.3
Fam196b

family with sequence similarity 196, member B

chr9_+_15520830 2.439 ENSMUST00000178999.1
Smco4
single-pass membrane protein with coiled-coil domains 4
chr8_+_70863127 2.399 ENSMUST00000050921.2
A230052G05Rik
RIKEN cDNA A230052G05 gene
chr2_+_35109482 2.396 ENSMUST00000028235.4
ENSMUST00000156933.1
ENSMUST00000028237.8
Cep110


centrosomal protein 110


chr5_-_120472763 2.316 ENSMUST00000052258.7
ENSMUST00000031594.6
Sdsl

serine dehydratase-like

chr12_-_98901478 2.308 ENSMUST00000065716.6
Eml5
echinoderm microtubule associated protein like 5
chr2_-_172370506 2.222 ENSMUST00000109139.1
ENSMUST00000028997.7
ENSMUST00000109140.3
Aurka


aurora kinase A


chr7_+_83631959 2.150 ENSMUST00000075418.7
ENSMUST00000117410.1
Stard5

StAR-related lipid transfer (START) domain containing 5

chr9_-_100571049 2.064 ENSMUST00000093792.2
Slc35g2
solute carrier family 35, member G2
chr7_+_112679314 2.050 ENSMUST00000084705.5
ENSMUST00000059768.10
Tead1

TEA domain family member 1

chr5_+_30105161 2.025 ENSMUST00000058045.4
Gareml
GRB2 associated, regulator of MAPK1-like
chr4_-_107923519 2.004 ENSMUST00000106719.1
ENSMUST00000106720.2
ENSMUST00000131644.1
ENSMUST00000030345.8
Cpt2



carnitine palmitoyltransferase 2



chr5_+_111733924 1.989 ENSMUST00000180627.1
Gm26897
predicted gene, 26897
chr4_-_154097105 1.988 ENSMUST00000105643.1
ENSMUST00000133533.1
ENSMUST00000097762.4
Trp73


transformation related protein 73


chr2_+_52038005 1.965 ENSMUST00000065927.5
Tnfaip6
tumor necrosis factor alpha induced protein 6
chrY_+_90755657 1.926 ENSMUST00000167967.2
Gm21857
predicted gene, 21857
chr10_-_23349887 1.908 ENSMUST00000074366.6
ENSMUST00000092665.4
Eya4

eyes absent 4 homolog (Drosophila)

chr4_-_45532470 1.888 ENSMUST00000147448.1
Shb
src homology 2 domain-containing transforming protein B
chr10_+_128092771 1.877 ENSMUST00000170054.2
ENSMUST00000045621.8
Baz2a

bromodomain adjacent to zinc finger domain, 2A

chr9_+_7764041 1.867 ENSMUST00000052865.9
Tmem123
transmembrane protein 123
chr9_-_97018823 1.847 ENSMUST00000055433.4
Spsb4
splA/ryanodine receptor domain and SOCS box containing 4
chr4_-_41695442 1.845 ENSMUST00000102961.3
ENSMUST00000064443.6
Cntfr

ciliary neurotrophic factor receptor

chr8_+_45507768 1.827 ENSMUST00000067065.7
ENSMUST00000098788.3
ENSMUST00000067107.7
ENSMUST00000171337.2
ENSMUST00000138049.1
ENSMUST00000141039.1
Sorbs2





sorbin and SH3 domain containing 2





chr7_-_99353104 1.819 ENSMUST00000169437.1
ENSMUST00000094154.4
Serpinh1

serine (or cysteine) peptidase inhibitor, clade H, member 1

chr1_-_193273099 1.802 ENSMUST00000009777.2
G0s2
G0/G1 switch gene 2
chr11_-_115813621 1.768 ENSMUST00000041684.4
ENSMUST00000156812.1
Caskin2

CASK-interacting protein 2

chr5_-_62766153 1.759 ENSMUST00000076623.4
Arap2
ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2
chr1_-_133424377 1.754 ENSMUST00000153799.1
Sox13
SRY-box containing gene 13
chr6_-_142507805 1.751 ENSMUST00000134191.1
ENSMUST00000032373.5
Ldhb

lactate dehydrogenase B

chr10_-_81349085 1.747 ENSMUST00000141171.1
Hmg20b
high mobility group 20B
chr7_+_112679327 1.744 ENSMUST00000106638.2
Tead1
TEA domain family member 1
chr1_+_104768510 1.720 ENSMUST00000062528.8
Cdh20
cadherin 20
chr13_+_75839868 1.702 ENSMUST00000022082.7
Glrx
glutaredoxin
chr10_-_80421847 1.688 ENSMUST00000156244.1
Tcf3
transcription factor 3
chr4_+_43267165 1.687 ENSMUST00000107942.2
ENSMUST00000102953.3
Atp8b5

ATPase, class I, type 8B, member 5

chr3_-_121171678 1.651 ENSMUST00000170781.1
ENSMUST00000039761.5
ENSMUST00000106467.1
ENSMUST00000106466.3
ENSMUST00000164925.2
Rwdd3




RWD domain containing 3




chr7_+_75610038 1.646 ENSMUST00000125771.1
Akap13
A kinase (PRKA) anchor protein 13
chr17_-_15375969 1.632 ENSMUST00000014917.7
Dll1
delta-like 1 (Drosophila)
chr7_+_92561141 1.620 ENSMUST00000032842.6
ENSMUST00000085017.4
Ccdc90b

coiled-coil domain containing 90B

chr12_+_37880700 1.616 ENSMUST00000040500.7
Dgkb
diacylglycerol kinase, beta
chr10_+_121033960 1.594 ENSMUST00000020439.4
ENSMUST00000175867.1
Wif1

Wnt inhibitory factor 1

chr2_-_26246707 1.570 ENSMUST00000166349.1
C030048H21Rik
RIKEN cDNA C030048H21 gene
chr18_-_24020307 1.541 ENSMUST00000153337.1
ENSMUST00000148525.1
Zfp191

zinc finger protein 191

chr2_+_25180737 1.539 ENSMUST00000104999.2
Nrarp
Notch-regulated ankyrin repeat protein
chr7_-_70366735 1.531 ENSMUST00000089565.5
Nr2f2
nuclear receptor subfamily 2, group F, member 2
chr5_-_5664196 1.524 ENSMUST00000061008.3
ENSMUST00000054865.6
A330021E22Rik

RIKEN cDNA A330021E22 gene

chr7_-_44815658 1.523 ENSMUST00000107893.1
Atf5
activating transcription factor 5
chr3_+_86224665 1.520 ENSMUST00000107635.1
Lrba
LPS-responsive beige-like anchor
chr4_-_147936713 1.465 ENSMUST00000105712.1
ENSMUST00000019199.7
Plod1

procollagen-lysine, 2-oxoglutarate 5-dioxygenase 1

chr8_-_80739497 1.447 ENSMUST00000043359.8
Smarca5
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 5
chr11_+_120949053 1.435 ENSMUST00000154187.1
ENSMUST00000100130.3
ENSMUST00000129473.1
ENSMUST00000168579.1
Slc16a3



solute carrier family 16 (monocarboxylic acid transporters), member 3



chr2_+_120463566 1.424 ENSMUST00000028749.7
ENSMUST00000110721.1
Capn3

calpain 3

chr16_-_55934845 1.423 ENSMUST00000121129.1
ENSMUST00000023270.7
Cep97

centrosomal protein 97

chr5_+_139423151 1.414 ENSMUST00000066211.4
Gper1
G protein-coupled estrogen receptor 1
chr9_-_114781986 1.399 ENSMUST00000035009.8
ENSMUST00000084867.7
Cmtm7

CKLF-like MARVEL transmembrane domain containing 7

chr19_+_5366764 1.398 ENSMUST00000025759.7
Eif1ad
eukaryotic translation initiation factor 1A domain containing
chr4_-_11254248 1.390 ENSMUST00000044616.3
ENSMUST00000108319.2
ENSMUST00000108318.2
Ints8


integrator complex subunit 8


chr9_-_77544870 1.388 ENSMUST00000183873.1
Lrrc1
leucine rich repeat containing 1
chr6_-_95718800 1.383 ENSMUST00000079847.5
Suclg2
succinate-Coenzyme A ligase, GDP-forming, beta subunit
chr19_+_25505618 1.371 ENSMUST00000025755.4
Dmrt1
doublesex and mab-3 related transcription factor 1
chr13_+_44729794 1.369 ENSMUST00000172830.1
Jarid2
jumonji, AT rich interactive domain 2
chr19_-_58454435 1.355 ENSMUST00000169850.1
Gfra1
glial cell line derived neurotrophic factor family receptor alpha 1
chr8_+_95633500 1.349 ENSMUST00000034094.9
Gins3
GINS complex subunit 3 (Psf3 homolog)
chr10_+_41810528 1.335 ENSMUST00000099931.3
Sesn1
sestrin 1
chr5_-_5694024 1.323 ENSMUST00000115425.2
ENSMUST00000115427.1
ENSMUST00000115424.2
ENSMUST00000015797.4
Steap2



six transmembrane epithelial antigen of prostate 2



chr7_+_25681158 1.313 ENSMUST00000108403.3
B9d2
B9 protein domain 2
chr17_-_70851710 1.313 ENSMUST00000166395.2
Tgif1
TGFB-induced factor homeobox 1
chr6_-_72235559 1.300 ENSMUST00000042646.7
Atoh8
atonal homolog 8 (Drosophila)
chr12_+_29938036 1.286 ENSMUST00000122328.1
ENSMUST00000118321.1
Pxdn

peroxidasin homolog (Drosophila)

chr5_-_123749393 1.264 ENSMUST00000057795.5
ENSMUST00000111515.1
ENSMUST00000182309.1
Rsrc2


arginine/serine-rich coiled-coil 2


chr5_-_123749371 1.250 ENSMUST00000182955.1
ENSMUST00000182489.1
ENSMUST00000050827.7
Rsrc2


arginine/serine-rich coiled-coil 2


chrX_-_157568983 1.244 ENSMUST00000065806.4
Yy2
Yy2 transcription factor
chr12_-_91746020 1.243 ENSMUST00000166967.1
Ston2
stonin 2
chr1_-_79858627 1.219 ENSMUST00000027467.4
Serpine2
serine (or cysteine) peptidase inhibitor, clade E, member 2
chr2_+_144527718 1.214 ENSMUST00000028914.2
ENSMUST00000110017.2
Polr3f

polymerase (RNA) III (DNA directed) polypeptide F

chr4_+_86748526 1.214 ENSMUST00000082026.7
ENSMUST00000045512.8
Dennd4c

DENN/MADD domain containing 4C

chr13_+_44729535 1.213 ENSMUST00000174068.1
Jarid2
jumonji, AT rich interactive domain 2
chr4_+_48539909 1.198 ENSMUST00000061135.1
Msantd3
Myb/SANT-like DNA-binding domain containing 3
chr1_-_136234113 1.191 ENSMUST00000120339.1
ENSMUST00000048668.8
5730559C18Rik

RIKEN cDNA 5730559C18 gene

chr7_+_127471484 1.188 ENSMUST00000033095.8
Prr14
proline rich 14
chr14_+_79481164 1.177 ENSMUST00000040131.5
Elf1
E74-like factor 1
chr4_+_62525369 1.174 ENSMUST00000062145.1
4933430I17Rik
RIKEN cDNA 4933430I17 gene
chr8_+_47533639 1.172 ENSMUST00000033973.7
ENSMUST00000176379.1
Rwdd4a

RWD domain containing 4A

chr16_-_55934797 1.168 ENSMUST00000122280.1
ENSMUST00000121703.2
Cep97

centrosomal protein 97

chr10_+_128238034 1.162 ENSMUST00000105245.2
Timeless
timeless circadian clock 1
chr1_-_51915901 1.158 ENSMUST00000018561.7
ENSMUST00000114537.2
Myo1b

myosin IB

chr16_+_77014069 1.153 ENSMUST00000023580.6
Usp25
ubiquitin specific peptidase 25
chr1_+_187215501 1.150 ENSMUST00000097443.3
ENSMUST00000065573.7
ENSMUST00000110943.2
ENSMUST00000044812.5
Gpatch2



G patch domain containing 2



chr4_+_48540067 1.148 ENSMUST00000064807.2
Msantd3
Myb/SANT-like DNA-binding domain containing 3
chr15_+_100304782 1.142 ENSMUST00000067752.3
Mettl7a1
methyltransferase like 7A1
chr3_-_84305385 1.140 ENSMUST00000122849.1
ENSMUST00000132283.1
Trim2

tripartite motif-containing 2

chr1_-_51915968 1.130 ENSMUST00000046390.7
Myo1b
myosin IB
chr6_+_53573364 1.116 ENSMUST00000047450.7
Creb5
cAMP responsive element binding protein 5
chr19_-_10203880 1.115 ENSMUST00000142241.1
ENSMUST00000116542.2
ENSMUST00000025651.5
ENSMUST00000156291.1
Fen1



flap structure specific endonuclease 1



chr4_+_109407087 1.115 ENSMUST00000064129.7
ENSMUST00000106619.1
Ttc39a

tetratricopeptide repeat domain 39A

chr7_-_141443314 1.111 ENSMUST00000106005.2
Lrdd
leucine-rich and death domain containing
chr5_-_124354671 1.089 ENSMUST00000031341.4
Cdk2ap1
CDK2 (cyclin-dependent kinase 2)-associated protein 1
chr5_-_137116177 1.088 ENSMUST00000054384.5
ENSMUST00000152207.1
Trim56

tripartite motif-containing 56

chr9_-_77544829 1.078 ENSMUST00000183734.1
Lrrc1
leucine rich repeat containing 1
chr15_+_100353149 1.076 ENSMUST00000088142.5
ENSMUST00000176287.1
ENSMUST00000075675.5
Mettl7a2

AB099516
methyltransferase like 7A2

cDNA sequence AB099516
chr13_-_98926374 1.074 ENSMUST00000109401.1
Tnpo1
transportin 1
chr4_+_62965560 1.055 ENSMUST00000030043.6
ENSMUST00000107415.1
ENSMUST00000064814.5
Zfp618


zinc finger protein 618


chr10_+_86302854 1.046 ENSMUST00000132307.1
Timp3
tissue inhibitor of metalloproteinase 3
chr2_-_125625065 1.021 ENSMUST00000089776.2
Cep152
centrosomal protein 152
chr5_+_32611171 1.019 ENSMUST00000072311.6
ENSMUST00000168707.2
Yes1

Yamaguchi sarcoma viral (v-yes) oncogene homolog 1

chr17_+_36958571 1.019 ENSMUST00000040177.6
Znrd1as
Znrd1 antisense
chr17_-_25727364 1.018 ENSMUST00000170070.1
ENSMUST00000048054.7
Chtf18

CTF18, chromosome transmission fidelity factor 18

chr2_-_156857946 1.015 ENSMUST00000099141.2
4930518I15Rik
RIKEN cDNA 4930518I15 gene
chr13_-_3918157 1.013 ENSMUST00000091853.4
Net1
neuroepithelial cell transforming gene 1
chr1_-_44101661 1.002 ENSMUST00000152239.1
Tex30
testis expressed 30
chr14_-_79481268 0.999 ENSMUST00000022601.5
Wbp4
WW domain binding protein 4
chr5_+_76656512 0.992 ENSMUST00000086909.4
Gm10430
predicted gene 10430
chr4_+_40722461 0.985 ENSMUST00000030118.3
Dnaja1
DnaJ (Hsp40) homolog, subfamily A, member 1
chr5_+_104775911 0.983 ENSMUST00000055593.7
Gm8258
predicted gene 8258
chr19_-_28967794 0.977 ENSMUST00000162110.1
4430402I18Rik
RIKEN cDNA 4430402I18 gene
chr1_+_95313607 0.967 ENSMUST00000059975.6
Fam174a
family with sequence similarity 174, member A
chr2_+_119897212 0.963 ENSMUST00000046717.6
ENSMUST00000110774.1
ENSMUST00000110773.2
ENSMUST00000079934.5
ENSMUST00000156510.1
Mga




MAX gene associated




chr19_-_16780822 0.960 ENSMUST00000068156.6
Vps13a
vacuolar protein sorting 13A (yeast)
chr2_+_31759932 0.957 ENSMUST00000028190.6
Abl1
c-abl oncogene 1, non-receptor tyrosine kinase
chr5_-_116422858 0.949 ENSMUST00000036991.4
Hspb8
heat shock protein 8
chr2_+_59612034 0.948 ENSMUST00000112568.1
ENSMUST00000037526.4
Tanc1

tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 1

chr17_-_34627148 0.940 ENSMUST00000171376.1
ENSMUST00000169287.1
Ppt2

palmitoyl-protein thioesterase 2

chr9_+_18292267 0.938 ENSMUST00000001825.7
Chordc1
cysteine and histidine-rich domain (CHORD)-containing, zinc-binding protein 1
chr18_-_47368446 0.928 ENSMUST00000076043.6
ENSMUST00000135790.1
Sema6a

sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6A

chr14_-_101609033 0.922 ENSMUST00000161991.1
ENSMUST00000100340.3
Tbc1d4

TBC1 domain family, member 4

chr13_+_38204928 0.919 ENSMUST00000091641.5
ENSMUST00000178564.1
Snrnp48

small nuclear ribonucleoprotein 48 (U11/U12)

chr11_-_69858723 0.914 ENSMUST00000001626.3
ENSMUST00000108626.1
Tnk1

tyrosine kinase, non-receptor, 1

chr7_+_16781341 0.912 ENSMUST00000108496.2
Slc1a5
solute carrier family 1 (neutral amino acid transporter), member 5
chr4_+_108479081 0.910 ENSMUST00000155068.1
Zcchc11
zinc finger, CCHC domain containing 11
chr3_+_96161981 0.904 ENSMUST00000054356.9
Mtmr11
myotubularin related protein 11
chr6_-_118562226 0.901 ENSMUST00000112830.1
Ankrd26
ankyrin repeat domain 26
chr5_+_3571664 0.888 ENSMUST00000008451.5
1700109H08Rik
RIKEN cDNA 1700109H08 gene
chr10_-_127070254 0.886 ENSMUST00000060991.4
Tspan31
tetraspanin 31
chr14_-_118132763 0.880 ENSMUST00000022727.8
Tgds
TDP-glucose 4,6-dehydratase
chr14_+_31495065 0.880 ENSMUST00000022446.5
Eaf1
ELL associated factor 1
chr1_+_178798438 0.871 ENSMUST00000160789.1
Kif26b
kinesin family member 26B
chr9_-_65580040 0.865 ENSMUST00000068944.7
Plekho2
pleckstrin homology domain containing, family O member 2
chr19_-_4839286 0.854 ENSMUST00000037246.5
Ccs
copper chaperone for superoxide dismutase
chr7_-_141443989 0.853 ENSMUST00000026580.5
Lrdd
leucine-rich and death domain containing
chr1_-_45503282 0.851 ENSMUST00000086430.4
Col5a2
collagen, type V, alpha 2
chr2_-_181599128 0.850 ENSMUST00000060173.8
Samd10
sterile alpha motif domain containing 10
chr10_+_68723723 0.849 ENSMUST00000080995.6
Tmem26
transmembrane protein 26
chr3_-_84304762 0.837 ENSMUST00000107692.1
Trim2
tripartite motif-containing 2
chr2_+_31759993 0.836 ENSMUST00000124089.1
Abl1
c-abl oncogene 1, non-receptor tyrosine kinase
chr6_-_128438673 0.833 ENSMUST00000032508.4
Fkbp4
FK506 binding protein 4
chr17_-_23771543 0.829 ENSMUST00000086325.5
Flywch1
FLYWCH-type zinc finger 1
chrX_+_151522352 0.823 ENSMUST00000148622.1
Phf8
PHD finger protein 8
chrX_+_52791179 0.817 ENSMUST00000101588.1
Ccdc160
coiled-coil domain containing 160
chr1_+_167598450 0.814 ENSMUST00000111386.1
ENSMUST00000111384.1
Rxrg

retinoid X receptor gamma

chr9_+_74861888 0.813 ENSMUST00000056006.9
Onecut1
one cut domain, family member 1
chr8_+_95320440 0.801 ENSMUST00000162294.1
Tepp
testis, prostate and placenta expressed

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
1.8 5.3 GO:0030421 defecation(GO:0030421)
1.5 5.8 GO:0021698 cerebellar cortex structural organization(GO:0021698)
1.1 5.7 GO:0035262 gonad morphogenesis(GO:0035262)
1.1 5.4 GO:0003213 cardiac right atrium morphogenesis(GO:0003213)
1.0 4.2 GO:0055099 response to high density lipoprotein particle(GO:0055099) platelet dense granule organization(GO:0060155)
1.0 6.2 GO:0003350 pulmonary myocardium development(GO:0003350)
0.9 6.5 GO:1903690 negative regulation of wound healing, spreading of epidermal cells(GO:1903690)
0.8 3.3 GO:1902724 positive regulation of skeletal muscle satellite cell proliferation(GO:1902724) positive regulation of growth factor dependent skeletal muscle satellite cell proliferation(GO:1902728)
0.7 2.8 GO:0060032 notochord regression(GO:0060032)
0.7 2.8 GO:0046552 eye photoreceptor cell fate commitment(GO:0042706) photoreceptor cell fate commitment(GO:0046552)
0.7 3.4 GO:0034421 post-translational protein acetylation(GO:0034421)
0.7 4.6 GO:0035745 T-helper 2 cell cytokine production(GO:0035745)
0.6 1.8 GO:0003360 brainstem development(GO:0003360)
0.6 1.8 GO:1900275 negative regulation of phospholipase C activity(GO:1900275)
0.6 8.9 GO:0048387 negative regulation of retinoic acid receptor signaling pathway(GO:0048387)
0.6 2.2 GO:0007056 spindle assembly involved in female meiosis(GO:0007056) positive regulation of oocyte development(GO:0060282)
0.6 1.7 GO:1902071 positive regulation of cellular response to hypoxia(GO:1900039) regulation of hypoxia-inducible factor-1alpha signaling pathway(GO:1902071)
0.5 2.0 GO:0033326 cerebrospinal fluid secretion(GO:0033326)
0.5 1.4 GO:0070315 G1 to G0 transition involved in cell differentiation(GO:0070315)
0.4 3.8 GO:0014883 transition between fast and slow fiber(GO:0014883)
0.4 3.5 GO:0070874 negative regulation of glycogen biosynthetic process(GO:0045719) negative regulation of glycogen metabolic process(GO:0070874)
0.4 1.2 GO:1904975 response to bleomycin(GO:1904975) cellular response to bleomycin(GO:1904976)
0.4 1.5 GO:0046947 hydroxylysine metabolic process(GO:0046946) hydroxylysine biosynthetic process(GO:0046947)
0.4 2.5 GO:0060907 positive regulation of macrophage cytokine production(GO:0060907)
0.4 1.4 GO:1904706 regulation of adenylate cyclase activity involved in G-protein coupled receptor signaling pathway(GO:0010578) positive regulation of adenylate cyclase activity involved in G-protein coupled receptor signaling pathway(GO:0010579) negative regulation of vascular smooth muscle cell proliferation(GO:1904706) positive regulation of vascular smooth muscle cell differentiation(GO:1905065)
0.4 1.8 GO:0019244 lactate biosynthetic process from pyruvate(GO:0019244)
0.3 1.4 GO:0002337 B-1a B cell differentiation(GO:0002337)
0.3 1.0 GO:1903984 positive regulation of TRAIL-activated apoptotic signaling pathway(GO:1903984)
0.3 1.7 GO:2000587 negative regulation of platelet-derived growth factor receptor-beta signaling pathway(GO:2000587)
0.3 2.8 GO:0070986 left/right axis specification(GO:0070986)
0.3 1.5 GO:0060849 regulation of transcription involved in lymphatic endothelial cell fate commitment(GO:0060849)
0.3 1.2 GO:0010757 negative regulation of plasminogen activation(GO:0010757)
0.3 0.9 GO:0072092 ureteric bud invasion(GO:0072092) metanephric renal vesicle formation(GO:0072093)
0.3 0.9 GO:1903225 negative regulation of endodermal cell differentiation(GO:1903225)
0.3 1.7 GO:0002326 B cell lineage commitment(GO:0002326)
0.3 3.9 GO:0032048 cardiolipin metabolic process(GO:0032048)
0.3 1.6 GO:0071883 activation of MAPK activity by adrenergic receptor signaling pathway(GO:0071883)
0.3 0.8 GO:0035574 histone H4-K20 demethylation(GO:0035574)
0.3 1.6 GO:0044806 G-quadruplex DNA unwinding(GO:0044806)
0.3 1.3 GO:0098706 ferric iron import into cell(GO:0097461) ferric iron import across plasma membrane(GO:0098706)
0.3 9.0 GO:0060236 regulation of mitotic spindle organization(GO:0060236)
0.3 2.6 GO:0051574 positive regulation of histone H3-K9 methylation(GO:0051574)
0.3 0.8 GO:0032430 positive regulation of phospholipase A2 activity(GO:0032430)
0.2 3.1 GO:0000183 chromatin silencing at rDNA(GO:0000183)
0.2 1.9 GO:0016576 histone dephosphorylation(GO:0016576)
0.2 1.4 GO:0060903 positive regulation of meiosis I(GO:0060903)
0.2 1.9 GO:1900194 negative regulation of oocyte maturation(GO:1900194)
0.2 0.8 GO:0055071 cellular manganese ion homeostasis(GO:0030026) Golgi calcium ion homeostasis(GO:0032468) manganese ion homeostasis(GO:0055071)
0.2 2.2 GO:0070508 sterol import(GO:0035376) cholesterol import(GO:0070508)
0.2 0.4 GO:2000981 negative regulation of mechanoreceptor differentiation(GO:0045632) negative regulation of inner ear receptor cell differentiation(GO:2000981)
0.2 0.6 GO:0006434 seryl-tRNA aminoacylation(GO:0006434)
0.2 0.8 GO:0036091 positive regulation of transcription from RNA polymerase II promoter in response to oxidative stress(GO:0036091)
0.2 0.7 GO:0070213 protein auto-ADP-ribosylation(GO:0070213)
0.2 1.1 GO:0043137 DNA replication, removal of RNA primer(GO:0043137) positive regulation of sister chromatid cohesion(GO:0045876)
0.2 4.8 GO:0046596 regulation of viral entry into host cell(GO:0046596)
0.2 0.9 GO:0006868 glutamine transport(GO:0006868)
0.2 0.7 GO:0045343 MHC class I biosynthetic process(GO:0045341) regulation of MHC class I biosynthetic process(GO:0045343) positive regulation of MHC class I biosynthetic process(GO:0045345) positive regulation of NK T cell activation(GO:0051135)
0.2 1.3 GO:0071802 negative regulation of podosome assembly(GO:0071802)
0.2 2.4 GO:1904293 negative regulation of ERAD pathway(GO:1904293)
0.2 0.8 GO:0090370 negative regulation of cholesterol efflux(GO:0090370)
0.2 0.9 GO:2000298 regulation of Rho-dependent protein serine/threonine kinase activity(GO:2000298)
0.2 0.5 GO:0045819 plasmacytoid dendritic cell activation(GO:0002270) positive regulation of glycogen catabolic process(GO:0045819)
0.2 1.4 GO:0006104 succinyl-CoA metabolic process(GO:0006104)
0.2 0.5 GO:0072717 cellular response to actinomycin D(GO:0072717)
0.1 0.4 GO:0097089 methyl-branched fatty acid metabolic process(GO:0097089)
0.1 1.2 GO:0014807 regulation of somitogenesis(GO:0014807)
0.1 1.0 GO:0098535 de novo centriole assembly(GO:0098535)
0.1 0.1 GO:0006532 aspartate biosynthetic process(GO:0006532)
0.1 0.4 GO:0030070 insulin processing(GO:0030070)
0.1 1.4 GO:0035873 lactate transport(GO:0015727) lactate transmembrane transport(GO:0035873) plasma membrane lactate transport(GO:0035879)
0.1 0.7 GO:0021914 negative regulation of smoothened signaling pathway involved in ventral spinal cord patterning(GO:0021914)
0.1 0.4 GO:1904179 positive regulation of adipose tissue development(GO:1904179)
0.1 0.4 GO:0048633 positive regulation of skeletal muscle tissue growth(GO:0048633)
0.1 1.0 GO:1900262 regulation of DNA-directed DNA polymerase activity(GO:1900262) positive regulation of DNA-directed DNA polymerase activity(GO:1900264)
0.1 0.2 GO:0072076 nephrogenic mesenchyme development(GO:0072076)
0.1 0.4 GO:0090285 negative regulation of protein glycosylation in Golgi(GO:0090285)
0.1 0.4 GO:1905000 regulation of membrane repolarization during atrial cardiac muscle cell action potential(GO:1905000)
0.1 1.1 GO:0070423 nucleotide-binding oligomerization domain containing signaling pathway(GO:0070423) nucleotide-binding oligomerization domain containing 2 signaling pathway(GO:0070431)
0.1 1.7 GO:0033234 negative regulation of protein sumoylation(GO:0033234)
0.1 0.6 GO:0035616 histone H2B conserved C-terminal lysine deubiquitination(GO:0035616)
0.1 1.5 GO:0046643 regulation of gamma-delta T cell differentiation(GO:0045586) regulation of gamma-delta T cell activation(GO:0046643)
0.1 0.9 GO:0010587 miRNA catabolic process(GO:0010587)
0.1 0.6 GO:1901165 positive regulation of trophoblast cell migration(GO:1901165)
0.1 1.5 GO:0021924 cell proliferation in external granule layer(GO:0021924) cerebellar granule cell precursor proliferation(GO:0021930)
0.1 0.3 GO:1990927 negative regulation of tumor necrosis factor secretion(GO:1904468) negative regulation of membrane invagination(GO:1905154) calcium ion regulated lysosome exocytosis(GO:1990927)
0.1 2.8 GO:0000132 establishment of mitotic spindle orientation(GO:0000132)
0.1 0.9 GO:0031339 negative regulation of vesicle fusion(GO:0031339)
0.1 0.3 GO:0001580 detection of chemical stimulus involved in sensory perception of bitter taste(GO:0001580)
0.1 0.8 GO:0006004 fucose metabolic process(GO:0006004)
0.1 0.9 GO:0042769 DNA damage response, detection of DNA damage(GO:0042769)
0.1 0.4 GO:0034239 regulation of macrophage fusion(GO:0034239)
0.1 0.2 GO:1905063 regulation of vascular smooth muscle cell differentiation(GO:1905063)
0.1 1.3 GO:0045603 positive regulation of endothelial cell differentiation(GO:0045603)
0.1 0.5 GO:1900029 positive regulation of ruffle assembly(GO:1900029)
0.1 0.4 GO:0015793 glycerol transport(GO:0015793)
0.1 0.6 GO:0007296 vitellogenesis(GO:0007296)
0.1 0.4 GO:1904659 glucose transmembrane transport(GO:1904659)
0.1 1.2 GO:0050858 negative regulation of antigen receptor-mediated signaling pathway(GO:0050858) negative regulation of T cell receptor signaling pathway(GO:0050860)
0.1 0.4 GO:0003420 regulation of growth plate cartilage chondrocyte proliferation(GO:0003420)
0.1 0.4 GO:0006564 L-serine biosynthetic process(GO:0006564)
0.1 0.1 GO:0032472 Golgi calcium ion transport(GO:0032472)
0.1 3.2 GO:0032611 interleukin-1 beta production(GO:0032611)
0.1 0.2 GO:0021759 globus pallidus development(GO:0021759)
0.1 0.5 GO:0030913 paranodal junction assembly(GO:0030913)
0.1 0.2 GO:0006533 aspartate catabolic process(GO:0006533) D-amino acid metabolic process(GO:0046416)
0.1 1.0 GO:0042744 hydrogen peroxide catabolic process(GO:0042744)
0.1 0.2 GO:0051026 chiasma assembly(GO:0051026)
0.1 0.7 GO:0042989 sequestering of actin monomers(GO:0042989)
0.1 0.5 GO:0046349 amino sugar biosynthetic process(GO:0046349)
0.1 0.5 GO:0003433 chondrocyte development involved in endochondral bone morphogenesis(GO:0003433)
0.1 0.2 GO:0036233 glycine import(GO:0036233)
0.1 0.4 GO:0034720 histone H3-K4 demethylation(GO:0034720)
0.1 1.3 GO:0098869 cellular oxidant detoxification(GO:0098869)
0.1 0.3 GO:0007113 endomitotic cell cycle(GO:0007113)
0.1 0.4 GO:0090527 actin filament reorganization(GO:0090527)
0.1 0.3 GO:0035752 lysosomal lumen pH elevation(GO:0035752)
0.1 3.1 GO:0045737 positive regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0045737)
0.1 1.0 GO:0036120 cellular response to platelet-derived growth factor stimulus(GO:0036120)
0.1 0.8 GO:0032287 peripheral nervous system myelin maintenance(GO:0032287)
0.1 0.1 GO:0061738 late endosomal microautophagy(GO:0061738)
0.1 1.3 GO:0045793 positive regulation of cell size(GO:0045793)
0.1 0.4 GO:0018401 peptidyl-proline hydroxylation to 4-hydroxy-L-proline(GO:0018401)
0.1 0.2 GO:0006203 dGTP catabolic process(GO:0006203) dATP catabolic process(GO:0046061)
0.1 1.4 GO:0016180 snRNA processing(GO:0016180)
0.1 1.0 GO:0045292 mRNA cis splicing, via spliceosome(GO:0045292)
0.1 0.9 GO:0046621 negative regulation of organ growth(GO:0046621)
0.1 0.2 GO:0060800 regulation of cell differentiation involved in embryonic placenta development(GO:0060800)
0.1 0.3 GO:0061668 mitochondrial ribosome assembly(GO:0061668)
0.1 0.5 GO:0040016 embryonic cleavage(GO:0040016)
0.1 0.4 GO:0033353 S-adenosylmethionine cycle(GO:0033353)
0.1 3.4 GO:0035019 somatic stem cell population maintenance(GO:0035019)
0.1 1.4 GO:0006801 superoxide metabolic process(GO:0006801)
0.1 3.1 GO:0002066 columnar/cuboidal epithelial cell development(GO:0002066)
0.1 0.2 GO:0002946 tRNA C5-cytosine methylation(GO:0002946)
0.1 0.3 GO:0042276 error-prone translesion synthesis(GO:0042276)
0.1 0.6 GO:0038166 angiotensin-activated signaling pathway(GO:0038166)
0.0 2.2 GO:0045600 positive regulation of fat cell differentiation(GO:0045600)
0.0 0.1 GO:1900186 negative regulation of clathrin-mediated endocytosis(GO:1900186)
0.0 0.2 GO:0060040 retinal bipolar neuron differentiation(GO:0060040)
0.0 0.7 GO:0030813 positive regulation of nucleotide catabolic process(GO:0030813) positive regulation of glycolytic process(GO:0045821) positive regulation of cofactor metabolic process(GO:0051194) positive regulation of coenzyme metabolic process(GO:0051197)
0.0 0.4 GO:0006348 chromatin silencing at telomere(GO:0006348)
0.0 0.4 GO:0060766 negative regulation of androgen receptor signaling pathway(GO:0060766)
0.0 0.8 GO:0031018 endocrine pancreas development(GO:0031018)
0.0 0.8 GO:0051044 positive regulation of membrane protein ectodomain proteolysis(GO:0051044)
0.0 0.8 GO:0006825 copper ion transport(GO:0006825)
0.0 0.1 GO:0046340 diacylglycerol catabolic process(GO:0046340)
0.0 0.8 GO:1901522 positive regulation of transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus(GO:1901522)
0.0 0.8 GO:0097062 dendritic spine maintenance(GO:0097062)
0.0 0.2 GO:0002862 negative regulation of inflammatory response to antigenic stimulus(GO:0002862)
0.0 0.5 GO:0006610 ribosomal protein import into nucleus(GO:0006610)
0.0 1.8 GO:0003301 physiological muscle hypertrophy(GO:0003298) physiological cardiac muscle hypertrophy(GO:0003301) cell growth involved in cardiac muscle cell development(GO:0061049)
0.0 1.4 GO:0006383 transcription from RNA polymerase III promoter(GO:0006383)
0.0 0.6 GO:0046855 inositol phosphate dephosphorylation(GO:0046855)
0.0 0.6 GO:0045947 negative regulation of translational initiation(GO:0045947)
0.0 0.2 GO:1902268 negative regulation of polyamine transmembrane transport(GO:1902268)
0.0 0.2 GO:0006741 NADP biosynthetic process(GO:0006741)
0.0 0.2 GO:0071894 histone H2B conserved C-terminal lysine ubiquitination(GO:0071894)
0.0 0.2 GO:0071985 multivesicular body sorting pathway(GO:0071985)
0.0 0.3 GO:0051490 negative regulation of filopodium assembly(GO:0051490)
0.0 0.1 GO:1902913 positive regulation of melanocyte differentiation(GO:0045636) positive regulation of neuroepithelial cell differentiation(GO:1902913)
0.0 0.2 GO:0090037 positive regulation of protein kinase C signaling(GO:0090037)
0.0 1.0 GO:0010842 retina layer formation(GO:0010842)
0.0 0.2 GO:1903847 regulation of aorta morphogenesis(GO:1903847) positive regulation of aorta morphogenesis(GO:1903849)
0.0 1.1 GO:0048025 negative regulation of mRNA splicing, via spliceosome(GO:0048025)
0.0 0.4 GO:0019321 pentose metabolic process(GO:0019321)
0.0 0.1 GO:0030299 intestinal cholesterol absorption(GO:0030299)
0.0 0.0 GO:0006933 negative regulation of cell adhesion involved in substrate-bound cell migration(GO:0006933)
0.0 0.5 GO:0070914 UV-damage excision repair(GO:0070914)
0.0 0.6 GO:0007205 protein kinase C-activating G-protein coupled receptor signaling pathway(GO:0007205)
0.0 0.5 GO:0042182 ketone catabolic process(GO:0042182)
0.0 0.5 GO:0060765 regulation of androgen receptor signaling pathway(GO:0060765)
0.0 0.2 GO:1900364 negative regulation of mRNA polyadenylation(GO:1900364)
0.0 0.1 GO:0033566 gamma-tubulin complex localization(GO:0033566)
0.0 0.2 GO:2000279 negative regulation of DNA biosynthetic process(GO:2000279)
0.0 0.4 GO:0030238 male sex determination(GO:0030238)
0.0 0.4 GO:0060363 cranial suture morphogenesis(GO:0060363)
0.0 0.1 GO:0046549 retinal cone cell differentiation(GO:0042670) retinal cone cell development(GO:0046549)
0.0 2.0 GO:0050728 negative regulation of inflammatory response(GO:0050728)
0.0 1.1 GO:0015914 phospholipid transport(GO:0015914)
0.0 1.7 GO:2001238 positive regulation of extrinsic apoptotic signaling pathway(GO:2001238)
0.0 0.1 GO:0031584 activation of phospholipase D activity(GO:0031584)
0.0 0.1 GO:0034498 early endosome to Golgi transport(GO:0034498)
0.0 0.4 GO:0051451 myoblast migration(GO:0051451)
0.0 1.1 GO:0060612 adipose tissue development(GO:0060612)
0.0 0.5 GO:0045116 protein neddylation(GO:0045116)
0.0 0.3 GO:0070544 histone H3-K36 demethylation(GO:0070544)
0.0 0.2 GO:0071157 negative regulation of cell cycle arrest(GO:0071157)
0.0 0.3 GO:0019369 arachidonic acid metabolic process(GO:0019369)
0.0 0.0 GO:0021764 amygdala development(GO:0021764)
0.0 0.1 GO:0030576 Cajal body organization(GO:0030576)
0.0 0.9 GO:0071526 semaphorin-plexin signaling pathway(GO:0071526)
0.0 0.4 GO:0030970 retrograde protein transport, ER to cytosol(GO:0030970)
0.0 0.5 GO:0033622 integrin activation(GO:0033622)
0.0 0.1 GO:0031282 regulation of guanylate cyclase activity(GO:0031282)
0.0 0.9 GO:0038083 peptidyl-tyrosine autophosphorylation(GO:0038083)
0.0 0.4 GO:0006491 N-glycan processing(GO:0006491)
0.0 1.7 GO:0050772 positive regulation of axonogenesis(GO:0050772)
0.0 0.2 GO:0045899 positive regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0045899)
0.0 0.2 GO:0031119 tRNA pseudouridine synthesis(GO:0031119)
0.0 0.2 GO:0048311 mitochondrion distribution(GO:0048311)
0.0 0.1 GO:0031915 positive regulation of synaptic plasticity(GO:0031915)
0.0 1.8 GO:1990830 response to leukemia inhibitory factor(GO:1990823) cellular response to leukemia inhibitory factor(GO:1990830)
0.0 0.4 GO:0045103 intermediate filament-based process(GO:0045103)
0.0 0.2 GO:0045830 positive regulation of isotype switching(GO:0045830)
0.0 0.0 GO:0035021 negative regulation of Rac protein signal transduction(GO:0035021)
0.0 0.9 GO:0010923 negative regulation of phosphatase activity(GO:0010923)
0.0 0.4 GO:0046470 phosphatidylcholine metabolic process(GO:0046470)
0.0 0.1 GO:0070125 mitochondrial translational elongation(GO:0070125)
0.0 0.4 GO:0007249 I-kappaB kinase/NF-kappaB signaling(GO:0007249)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.9 3.8 GO:0071148 TEAD-1-YAP complex(GO:0071148)
0.8 6.4 GO:0005818 aster(GO:0005818)
0.7 2.2 GO:0042585 germinal vesicle(GO:0042585)
0.6 1.8 GO:0097059 CNTFR-CLCF1 complex(GO:0097059)
0.5 2.5 GO:0002193 MAML1-RBP-Jkappa- ICN1 complex(GO:0002193)
0.4 6.6 GO:0045180 basal cortex(GO:0045180)
0.4 1.7 GO:0002111 BRCA2-BRAF35 complex(GO:0002111)
0.4 1.9 GO:0033553 rDNA heterochromatin(GO:0033553)
0.3 3.7 GO:0031618 nuclear pericentric heterochromatin(GO:0031618)
0.3 0.9 GO:0005588 collagen type V trimer(GO:0005588)
0.3 4.0 GO:0030061 mitochondrial crista(GO:0030061)
0.3 0.8 GO:0032311 angiogenin-PRI complex(GO:0032311)
0.2 4.4 GO:0034364 high-density lipoprotein particle(GO:0034364)
0.2 1.4 GO:0005677 chromatin silencing complex(GO:0005677)
0.2 1.4 GO:0030062 mitochondrial tricarboxylic acid cycle enzyme complex(GO:0030062)
0.2 0.6 GO:0099573 glutamatergic postsynaptic density(GO:0099573)
0.2 1.0 GO:0098536 deuterosome(GO:0098536)
0.2 4.3 GO:0005921 gap junction(GO:0005921)
0.2 0.8 GO:0032389 MutLalpha complex(GO:0032389)
0.2 1.2 GO:0031232 extrinsic component of external side of plasma membrane(GO:0031232)
0.1 1.4 GO:0032591 dendritic spine membrane(GO:0032591)
0.1 4.2 GO:0051233 spindle midzone(GO:0051233)
0.1 0.6 GO:0008622 epsilon DNA polymerase complex(GO:0008622)
0.1 7.9 GO:0016459 myosin complex(GO:0016459)
0.1 1.0 GO:0031390 Ctf18 RFC-like complex(GO:0031390)
0.1 1.3 GO:0061700 GATOR2 complex(GO:0061700)
0.1 2.6 GO:0035098 ESC/E(Z) complex(GO:0035098)
0.1 0.4 GO:0016222 procollagen-proline 4-dioxygenase complex(GO:0016222)
0.1 0.6 GO:0005785 signal recognition particle receptor complex(GO:0005785)
0.1 1.4 GO:0032039 integrator complex(GO:0032039)
0.1 1.2 GO:0032593 insulin-responsive compartment(GO:0032593)
0.1 1.3 GO:0036038 MKS complex(GO:0036038)
0.1 1.2 GO:0097539 ciliary transition fiber(GO:0097539)
0.1 0.3 GO:0044300 cerebellar mossy fiber(GO:0044300)
0.1 4.8 GO:0016328 lateral plasma membrane(GO:0016328)
0.1 0.4 GO:0031523 Myb complex(GO:0031523)
0.1 1.4 GO:0005665 DNA-directed RNA polymerase II, core complex(GO:0005665)
0.1 0.8 GO:0071598 neuronal ribonucleoprotein granule(GO:0071598)
0.1 0.1 GO:0099524 region of cytosol(GO:0099522) postsynaptic cytosol(GO:0099524)
0.1 1.1 GO:0005666 DNA-directed RNA polymerase III complex(GO:0005666)
0.1 4.5 GO:0019005 SCF ubiquitin ligase complex(GO:0019005)
0.1 0.4 GO:0032937 SREBP-SCAP-Insig complex(GO:0032937)
0.1 1.7 GO:0000788 nuclear nucleosome(GO:0000788)
0.1 0.3 GO:0097512 cardiac myofibril(GO:0097512)
0.1 0.6 GO:0034663 endoplasmic reticulum chaperone complex(GO:0034663)
0.0 0.7 GO:0031011 Ino80 complex(GO:0031011)
0.0 0.5 GO:0005671 Ada2/Gcn5/Ada3 transcription activator complex(GO:0005671)
0.0 0.3 GO:0071203 WASH complex(GO:0071203)
0.0 0.1 GO:0030905 retromer, tubulation complex(GO:0030905)
0.0 1.0 GO:0071339 MLL1/2 complex(GO:0044665) MLL1 complex(GO:0071339)
0.0 1.2 GO:0030140 trans-Golgi network transport vesicle(GO:0030140)
0.0 2.1 GO:0005882 intermediate filament(GO:0005882)
0.0 0.3 GO:0031595 nuclear proteasome complex(GO:0031595)
0.0 0.1 GO:0070033 synaptobrevin 2-SNAP-25-syntaxin-1a-complexin II complex(GO:0070033)
0.0 5.6 GO:0090575 RNA polymerase II transcription factor complex(GO:0090575)
0.0 0.5 GO:0031588 nucleotide-activated protein kinase complex(GO:0031588)
0.0 0.3 GO:0032009 early phagosome(GO:0032009)
0.0 2.0 GO:0005793 endoplasmic reticulum-Golgi intermediate compartment(GO:0005793)
0.0 0.6 GO:0000242 pericentriolar material(GO:0000242)
0.0 1.2 GO:0002102 podosome(GO:0002102)
0.0 2.0 GO:0005811 lipid particle(GO:0005811)
0.0 0.1 GO:0042589 zymogen granule membrane(GO:0042589)
0.0 1.7 GO:0005758 mitochondrial intermembrane space(GO:0005758)
0.0 0.2 GO:0031616 spindle pole centrosome(GO:0031616)
0.0 0.1 GO:0042622 photoreceptor outer segment membrane(GO:0042622)
0.0 5.7 GO:0016607 nuclear speck(GO:0016607)
0.0 0.8 GO:0045171 intercellular bridge(GO:0045171)
0.0 0.9 GO:0005871 kinesin complex(GO:0005871)
0.0 0.3 GO:0001741 XY body(GO:0001741)
0.0 0.5 GO:0000407 pre-autophagosomal structure(GO:0000407)
0.0 0.0 GO:0036449 microtubule minus-end(GO:0036449)
0.0 1.2 GO:0000502 proteasome complex(GO:0000502)
0.0 0.2 GO:0035631 CD40 receptor complex(GO:0035631)
0.0 0.3 GO:0043034 costamere(GO:0043034)
0.0 1.6 GO:0031234 extrinsic component of cytoplasmic side of plasma membrane(GO:0031234)
0.0 0.5 GO:0032809 neuronal cell body membrane(GO:0032809)
0.0 0.9 GO:0016605 PML body(GO:0016605)
0.0 2.4 GO:0005802 trans-Golgi network(GO:0005802)
0.0 0.4 GO:0044295 axonal growth cone(GO:0044295)
0.0 0.8 GO:0030315 T-tubule(GO:0030315)
0.0 0.9 GO:0045177 apical part of cell(GO:0045177)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
1.4 4.2 GO:0030226 apolipoprotein receptor activity(GO:0030226) apolipoprotein A-I receptor activity(GO:0034188) phosphatidylserine-translocating ATPase activity(GO:0090556)
1.1 4.5 GO:0061575 cyclin-dependent protein serine/threonine kinase activator activity(GO:0061575)
1.0 2.9 GO:0005110 frizzled-2 binding(GO:0005110)
0.7 2.2 GO:0032052 bile acid binding(GO:0032052)
0.7 6.4 GO:0061676 importin-alpha family protein binding(GO:0061676)
0.6 2.3 GO:0003941 L-serine ammonia-lyase activity(GO:0003941)
0.6 1.7 GO:0015038 glutathione disulfide oxidoreductase activity(GO:0015038) protein-disulfide reductase (glutathione) activity(GO:0019153)
0.6 3.4 GO:0004468 lysine N-acetyltransferase activity, acting on acetyl phosphate as donor(GO:0004468)
0.5 1.0 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.5 6.2 GO:0038191 neuropilin binding(GO:0038191)
0.5 1.4 GO:0004774 succinate-CoA ligase activity(GO:0004774)
0.4 2.2 GO:0035174 histone serine kinase activity(GO:0035174)
0.4 1.3 GO:0008823 cupric reductase activity(GO:0008823) ferric-chelate reductase (NADPH) activity(GO:0052851)
0.4 1.8 GO:0004459 L-lactate dehydrogenase activity(GO:0004459)
0.4 1.2 GO:0005118 sevenless binding(GO:0005118)
0.4 8.9 GO:0070410 co-SMAD binding(GO:0070410)
0.4 2.0 GO:0004095 carnitine O-palmitoyltransferase activity(GO:0004095) O-palmitoyltransferase activity(GO:0016416)
0.4 1.5 GO:0008475 procollagen-lysine 5-dioxygenase activity(GO:0008475)
0.4 1.4 GO:0004784 superoxide dismutase activity(GO:0004784) oxidoreductase activity, acting on superoxide radicals as acceptor(GO:0016721)
0.4 3.2 GO:0031730 CCR5 chemokine receptor binding(GO:0031730)
0.3 1.8 GO:0004897 ciliary neurotrophic factor receptor activity(GO:0004897)
0.3 1.7 GO:0070644 vitamin D response element binding(GO:0070644)
0.3 0.8 GO:0047256 beta-galactosyl-N-acetylglucosaminylgalactosylglucosyl-ceramide beta-1,3-acetylglucosaminyltransferase activity(GO:0008457) lactosylceramide 1,3-N-acetyl-beta-D-glucosaminyltransferase activity(GO:0047256)
0.3 0.8 GO:0035575 histone demethylase activity (H4-K20 specific)(GO:0035575)
0.2 1.1 GO:0017108 5'-flap endonuclease activity(GO:0017108)
0.2 2.2 GO:0008474 palmitoyl-(protein) hydrolase activity(GO:0008474) palmitoyl hydrolase activity(GO:0098599)
0.2 1.3 GO:0030284 estrogen receptor activity(GO:0030284)
0.2 1.4 GO:0015129 lactate transmembrane transporter activity(GO:0015129)
0.2 0.8 GO:0015410 manganese-transporting ATPase activity(GO:0015410)
0.2 3.8 GO:0001134 transcription factor activity, transcription factor recruiting(GO:0001134)
0.2 0.8 GO:0042806 fucose binding(GO:0042806)
0.2 0.6 GO:0004828 serine-tRNA ligase activity(GO:0004828)
0.2 0.7 GO:0008802 betaine-aldehyde dehydrogenase activity(GO:0008802)
0.2 0.9 GO:0050265 RNA uridylyltransferase activity(GO:0050265)
0.2 1.4 GO:0031432 titin binding(GO:0031432)
0.2 1.1 GO:0070728 leucine binding(GO:0070728)
0.2 1.9 GO:0001163 RNA polymerase I regulatory region sequence-specific DNA binding(GO:0001163) RNA polymerase I CORE element sequence-specific DNA binding(GO:0001164)
0.2 1.5 GO:0001972 retinoic acid binding(GO:0001972)
0.2 0.8 GO:0032767 copper-dependent protein binding(GO:0032767)
0.2 1.6 GO:0004691 cAMP-dependent protein kinase activity(GO:0004691)
0.2 2.5 GO:0030957 Tat protein binding(GO:0030957)
0.2 0.5 GO:0000402 open form four-way junction DNA binding(GO:0000401) crossed form four-way junction DNA binding(GO:0000402)
0.2 0.8 GO:0000405 bubble DNA binding(GO:0000405)
0.2 2.3 GO:0030898 actin-dependent ATPase activity(GO:0030898)
0.2 2.9 GO:0035497 cAMP response element binding(GO:0035497)
0.2 0.5 GO:0000253 3-keto sterol reductase activity(GO:0000253)
0.1 1.8 GO:0070097 delta-catenin binding(GO:0070097)
0.1 0.7 GO:0004382 guanosine-diphosphatase activity(GO:0004382)
0.1 0.8 GO:0001069 regulatory region RNA binding(GO:0001069)
0.1 0.8 GO:0004886 9-cis retinoic acid receptor activity(GO:0004886)
0.1 0.4 GO:0004647 phosphoserine phosphatase activity(GO:0004647)
0.1 4.2 GO:0008574 ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574)
0.1 0.4 GO:0052740 phosphatidylserine 1-acylhydrolase activity(GO:0052739) 1-acyl-2-lysophosphatidylserine acylhydrolase activity(GO:0052740)
0.1 1.0 GO:0019788 NEDD8 transferase activity(GO:0019788)
0.1 0.4 GO:0071633 dihydroceramidase activity(GO:0071633)
0.1 6.5 GO:0001784 phosphotyrosine binding(GO:0001784)
0.1 0.1 GO:0051371 muscle alpha-actinin binding(GO:0051371)
0.1 5.4 GO:0017112 Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.1 0.4 GO:0034647 histone demethylase activity (H3-trimethyl-K4 specific)(GO:0034647)
0.1 2.0 GO:0097371 MDM2/MDM4 family protein binding(GO:0097371)
0.1 2.0 GO:0005540 hyaluronic acid binding(GO:0005540)
0.1 0.3 GO:0008392 arachidonic acid epoxygenase activity(GO:0008392)
0.1 1.5 GO:0016290 palmitoyl-CoA hydrolase activity(GO:0016290)
0.1 1.7 GO:0000400 four-way junction DNA binding(GO:0000400)
0.1 1.2 GO:0000987 core promoter proximal region sequence-specific DNA binding(GO:0000987) core promoter proximal region DNA binding(GO:0001159)
0.1 0.6 GO:0042731 PH domain binding(GO:0042731)
0.1 1.0 GO:0003689 DNA clamp loader activity(GO:0003689) protein-DNA loading ATPase activity(GO:0033170)
0.1 0.4 GO:0015254 glycerol channel activity(GO:0015254)
0.1 0.4 GO:0034988 Fc-gamma receptor I complex binding(GO:0034988)
0.1 0.4 GO:0045131 pre-mRNA branch point binding(GO:0045131)
0.1 0.3 GO:0045322 unmethylated CpG binding(GO:0045322)
0.1 1.0 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.1 2.9 GO:0005112 Notch binding(GO:0005112)
0.1 0.5 GO:1990829 C-rich single-stranded DNA binding(GO:1990829)
0.1 1.1 GO:0005149 interleukin-1 receptor binding(GO:0005149)
0.1 2.6 GO:0008307 structural constituent of muscle(GO:0008307)
0.1 0.7 GO:0000774 adenyl-nucleotide exchange factor activity(GO:0000774)
0.1 2.1 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.1 2.6 GO:0032452 histone demethylase activity(GO:0032452)
0.1 0.4 GO:0004656 procollagen-proline 4-dioxygenase activity(GO:0004656) procollagen-proline dioxygenase activity(GO:0019798)
0.1 0.3 GO:0004045 aminoacyl-tRNA hydrolase activity(GO:0004045)
0.1 2.6 GO:0043027 cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027)
0.1 0.6 GO:0046790 virion binding(GO:0046790)
0.1 1.1 GO:0001056 RNA polymerase III activity(GO:0001056)
0.1 0.4 GO:0016176 superoxide-generating NADPH oxidase activator activity(GO:0016176)
0.1 0.9 GO:0030215 semaphorin receptor binding(GO:0030215)
0.1 0.4 GO:0061649 ubiquitinated histone binding(GO:0061649)
0.1 0.8 GO:0019855 calcium channel inhibitor activity(GO:0019855)
0.1 0.4 GO:0016802 adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802)
0.1 0.5 GO:0004679 AMP-activated protein kinase activity(GO:0004679)
0.1 0.4 GO:0015016 [heparan sulfate]-glucosamine N-sulfotransferase activity(GO:0015016)
0.1 0.6 GO:0001055 RNA polymerase II activity(GO:0001055)
0.1 1.0 GO:0017049 GTP-Rho binding(GO:0017049)
0.1 0.8 GO:1990825 sequence-specific mRNA binding(GO:1990825)
0.1 0.4 GO:0052629 phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity(GO:0052629)
0.1 0.6 GO:0008190 eukaryotic initiation factor 4E binding(GO:0008190)
0.1 0.6 GO:0004143 diacylglycerol kinase activity(GO:0004143)
0.1 0.4 GO:0035242 protein-arginine omega-N asymmetric methyltransferase activity(GO:0035242)
0.1 0.3 GO:0016018 cyclosporin A binding(GO:0016018)
0.1 0.6 GO:0009931 calcium-dependent protein serine/threonine kinase activity(GO:0009931)
0.0 1.1 GO:0004012 phospholipid-translocating ATPase activity(GO:0004012)
0.0 0.1 GO:0004069 L-aspartate:2-oxoglutarate aminotransferase activity(GO:0004069)
0.0 0.1 GO:0030249 guanylate cyclase regulator activity(GO:0030249)
0.0 0.3 GO:0036402 proteasome-activating ATPase activity(GO:0036402)
0.0 1.5 GO:1990841 promoter-specific chromatin binding(GO:1990841)
0.0 0.1 GO:0031686 A1 adenosine receptor binding(GO:0031686)
0.0 1.9 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.0 1.0 GO:0070064 proline-rich region binding(GO:0070064)
0.0 1.3 GO:0017147 Wnt-protein binding(GO:0017147)
0.0 0.3 GO:1901612 phosphatidylglycerol binding(GO:1901611) cardiolipin binding(GO:1901612)
0.0 1.8 GO:0051018 protein kinase A binding(GO:0051018)
0.0 0.4 GO:0031418 L-ascorbic acid binding(GO:0031418)
0.0 0.4 GO:0004571 mannosyl-oligosaccharide 1,2-alpha-mannosidase activity(GO:0004571)
0.0 0.2 GO:0008073 ornithine decarboxylase inhibitor activity(GO:0008073)
0.0 0.2 GO:0030983 mismatched DNA binding(GO:0030983)
0.0 1.7 GO:0005547 phosphatidylinositol-3,4,5-trisphosphate binding(GO:0005547)
0.0 3.4 GO:0003774 motor activity(GO:0003774)
0.0 0.5 GO:0022889 L-serine transmembrane transporter activity(GO:0015194) serine transmembrane transporter activity(GO:0022889)
0.0 0.4 GO:0016671 oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor(GO:0016671)
0.0 0.2 GO:0034452 dynactin binding(GO:0034452)
0.0 0.7 GO:0003950 NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.0 0.2 GO:0032554 purine deoxyribonucleotide binding(GO:0032554)
0.0 0.1 GO:1990460 leptin receptor binding(GO:1990460)
0.0 1.4 GO:0070888 E-box binding(GO:0070888)
0.0 0.2 GO:0005087 Ran guanyl-nucleotide exchange factor activity(GO:0005087)
0.0 0.7 GO:0017025 TBP-class protein binding(GO:0017025)
0.0 0.4 GO:0005355 glucose transmembrane transporter activity(GO:0005355)
0.0 0.3 GO:0004806 triglyceride lipase activity(GO:0004806)
0.0 0.3 GO:0045125 bioactive lipid receptor activity(GO:0045125)
0.0 0.2 GO:0008301 DNA binding, bending(GO:0008301)
0.0 0.5 GO:0042608 T cell receptor binding(GO:0042608)
0.0 3.2 GO:0008201 heparin binding(GO:0008201)
0.0 2.7 GO:0001158 enhancer sequence-specific DNA binding(GO:0001158)
0.0 0.9 GO:0004715 non-membrane spanning protein tyrosine kinase activity(GO:0004715)
0.0 0.2 GO:0061665 SUMO ligase activity(GO:0061665)
0.0 0.5 GO:0005251 delayed rectifier potassium channel activity(GO:0005251)
0.0 1.2 GO:0031491 nucleosome binding(GO:0031491)
0.0 0.2 GO:0004726 non-membrane spanning protein tyrosine phosphatase activity(GO:0004726)
0.0 0.7 GO:0003785 actin monomer binding(GO:0003785)
0.0 0.3 GO:0008430 selenium binding(GO:0008430)
0.0 0.6 GO:0005109 frizzled binding(GO:0005109)
0.0 1.4 GO:0030295 protein kinase activator activity(GO:0030295)
0.0 0.2 GO:0015187 glycine transmembrane transporter activity(GO:0015187)
0.0 0.2 GO:0031386 protein tag(GO:0031386)
0.0 0.2 GO:0003951 NAD+ kinase activity(GO:0003951)
0.0 0.4 GO:0010485 H4 histone acetyltransferase activity(GO:0010485)
0.0 0.3 GO:0008641 small protein activating enzyme activity(GO:0008641)
0.0 0.2 GO:0005229 intracellular calcium activated chloride channel activity(GO:0005229)
0.0 3.0 GO:0043565 sequence-specific DNA binding(GO:0043565)
0.0 0.5 GO:0070717 poly-purine tract binding(GO:0070717)
0.0 1.7 GO:0004843 thiol-dependent ubiquitin-specific protease activity(GO:0004843)
0.0 0.1 GO:0043812 phosphatidylinositol-4-phosphate phosphatase activity(GO:0043812)
0.0 1.0 GO:0016836 hydro-lyase activity(GO:0016836)
0.0 0.2 GO:0016428 tRNA (cytosine-5-)-methyltransferase activity(GO:0016428)
0.0 0.2 GO:0016641 oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor(GO:0016641)
0.0 0.1 GO:0043855 intracellular cyclic nucleotide activated cation channel activity(GO:0005221) cyclic nucleotide-gated ion channel activity(GO:0043855)
0.0 0.0 GO:0031735 CCR10 chemokine receptor binding(GO:0031735)
0.0 0.3 GO:0004190 aspartic-type endopeptidase activity(GO:0004190) aspartic-type peptidase activity(GO:0070001)
0.0 0.6 GO:0048487 beta-tubulin binding(GO:0048487)
0.0 0.6 GO:0016278 lysine N-methyltransferase activity(GO:0016278) protein-lysine N-methyltransferase activity(GO:0016279)
0.0 0.8 GO:0003705 transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0003705)
0.0 0.7 GO:0061631 ubiquitin conjugating enzyme activity(GO:0061631)
0.0 2.4 GO:0003714 transcription corepressor activity(GO:0003714)
0.0 0.2 GO:1990226 histone methyltransferase binding(GO:1990226)
0.0 0.7 GO:0017022 myosin binding(GO:0017022)
0.0 0.2 GO:0070016 armadillo repeat domain binding(GO:0070016)
0.0 0.3 GO:0003887 DNA-directed DNA polymerase activity(GO:0003887)
0.0 0.3 GO:0001221 transcription cofactor binding(GO:0001221)
0.0 0.4 GO:0051879 Hsp90 protein binding(GO:0051879)
0.0 0.9 GO:0005178 integrin binding(GO:0005178)
0.0 0.4 GO:0019200 carbohydrate kinase activity(GO:0019200)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 8.5 PID_AURORA_A_PATHWAY Aurora A signaling
0.2 3.3 ST_STAT3_PATHWAY STAT3 Pathway
0.2 5.3 PID_SYNDECAN_4_PATHWAY Syndecan-4-mediated signaling events
0.2 4.5 PID_WNT_SIGNALING_PATHWAY Wnt signaling network
0.1 5.0 PID_RXR_VDR_PATHWAY RXR and RAR heterodimerization with other nuclear receptor
0.1 0.4 ST_INTERFERON_GAMMA_PATHWAY Interferon gamma pathway.
0.1 4.2 PID_NETRIN_PATHWAY Netrin-mediated signaling events
0.1 4.1 PID_PS1_PATHWAY Presenilin action in Notch and Wnt signaling
0.1 1.9 PID_PDGFRA_PATHWAY PDGFR-alpha signaling pathway
0.1 4.9 PID_RET_PATHWAY Signaling events regulated by Ret tyrosine kinase
0.1 10.7 PID_SMAD2_3NUCLEAR_PATHWAY Regulation of nuclear SMAD2/3 signaling
0.1 2.8 PID_HEDGEHOG_2PATHWAY Signaling events mediated by the Hedgehog family
0.1 1.5 PID_PRL_SIGNALING_EVENTS_PATHWAY Signaling events mediated by PRL
0.1 0.4 PID_IL6_7_PATHWAY IL6-mediated signaling events
0.1 1.2 PID_CIRCADIAN_PATHWAY Circadian rhythm pathway
0.1 1.1 ST_G_ALPHA_S_PATHWAY G alpha s Pathway
0.1 2.3 PID_ATM_PATHWAY ATM pathway
0.1 6.4 NABA_ECM_AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.0 1.2 PID_ANGIOPOIETIN_RECEPTOR_PATHWAY Angiopoietin receptor Tie2-mediated signaling
0.0 1.8 PID_THROMBIN_PAR1_PATHWAY PAR1-mediated thrombin signaling events
0.0 1.5 PID_ARF6_PATHWAY Arf6 signaling events
0.0 0.8 PID_FOXM1_PATHWAY FOXM1 transcription factor network
0.0 1.4 PID_SYNDECAN_1_PATHWAY Syndecan-1-mediated signaling events
0.0 1.3 PID_REELIN_PATHWAY Reelin signaling pathway
0.0 0.9 PID_INSULIN_GLUCOSE_PATHWAY Insulin-mediated glucose transport
0.0 0.9 PID_IL1_PATHWAY IL1-mediated signaling events
0.0 1.4 PID_TELOMERASE_PATHWAY Regulation of Telomerase
0.0 0.5 PID_A6B1_A6B4_INTEGRIN_PATHWAY a6b1 and a6b4 Integrin signaling
0.0 0.3 PID_ERB_GENOMIC_PATHWAY Validated nuclear estrogen receptor beta network
0.0 0.3 PID_CONE_PATHWAY Visual signal transduction: Cones
0.0 0.4 PID_RANBP2_PATHWAY Sumoylation by RanBP2 regulates transcriptional repression
0.0 2.2 PID_ERBB1_DOWNSTREAM_PATHWAY ErbB1 downstream signaling
0.0 1.1 PID_PLK1_PATHWAY PLK1 signaling events
0.0 0.4 PID_WNT_NONCANONICAL_PATHWAY Noncanonical Wnt signaling pathway
0.0 1.1 PID_ERA_GENOMIC_PATHWAY Validated nuclear estrogen receptor alpha network
0.0 0.3 PID_P38_MK2_PATHWAY p38 signaling mediated by MAPKAP kinases
0.0 0.5 PID_AMB2_NEUTROPHILS_PATHWAY amb2 Integrin signaling
0.0 0.5 PID_VEGFR1_2_PATHWAY Signaling events mediated by VEGFR1 and VEGFR2
0.0 0.2 PID_CD40_PATHWAY CD40/CD40L signaling
0.0 0.5 WNT_SIGNALING Genes related to Wnt-mediated signal transduction
0.0 0.6 PID_NOTCH_PATHWAY Notch signaling pathway

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 4.2 REACTOME_HDL_MEDIATED_LIPID_TRANSPORT Genes involved in HDL-mediated lipid transport
0.3 3.7 REACTOME_IL_6_SIGNALING Genes involved in Interleukin-6 signaling
0.3 9.2 REACTOME_DOWNREGULATION_OF_SMAD2_3_SMAD4_TRANSCRIPTIONAL_ACTIVITY Genes involved in Downregulation of SMAD2/3:SMAD4 transcriptional activity
0.2 6.6 REACTOME_MYOGENESIS Genes involved in Myogenesis
0.2 3.5 REACTOME_SIGNAL_ATTENUATION Genes involved in Signal attenuation
0.2 1.9 REACTOME_RECEPTOR_LIGAND_BINDING_INITIATES_THE_SECOND_PROTEOLYTIC_CLEAVAGE_OF_NOTCH_RECEPTOR Genes involved in Receptor-ligand binding initiates the second proteolytic cleavage of Notch receptor
0.2 1.4 REACTOME_BILE_SALT_AND_ORGANIC_ANION_SLC_TRANSPORTERS Genes involved in Bile salt and organic anion SLC transporters
0.2 5.0 REACTOME_TIGHT_JUNCTION_INTERACTIONS Genes involved in Tight junction interactions
0.2 2.2 REACTOME_STEROID_HORMONES Genes involved in Steroid hormones
0.1 1.1 REACTOME_TRAF6_MEDIATED_IRF7_ACTIVATION_IN_TLR7_8_OR_9_SIGNALING Genes involved in TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling
0.1 3.8 REACTOME_YAP1_AND_WWTR1_TAZ_STIMULATED_GENE_EXPRESSION Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.1 1.1 REACTOME_REMOVAL_OF_THE_FLAP_INTERMEDIATE_FROM_THE_C_STRAND Genes involved in Removal of the Flap Intermediate from the C-strand
0.1 2.5 REACTOME_ACTIVATED_AMPK_STIMULATES_FATTY_ACID_OXIDATION_IN_MUSCLE Genes involved in Activated AMPK stimulates fatty-acid oxidation in muscle
0.1 0.7 REACTOME_REGULATION_OF_ORNITHINE_DECARBOXYLASE_ODC Genes involved in Regulation of ornithine decarboxylase (ODC)
0.1 1.8 REACTOME_PYRUVATE_METABOLISM Genes involved in Pyruvate metabolism
0.1 0.6 REACTOME_REPAIR_SYNTHESIS_FOR_GAP_FILLING_BY_DNA_POL_IN_TC_NER Genes involved in Repair synthesis for gap-filling by DNA polymerase in TC-NER
0.1 0.6 REACTOME_TRAFFICKING_AND_PROCESSING_OF_ENDOSOMAL_TLR Genes involved in Trafficking and processing of endosomal TLR
0.1 0.2 REACTOME_EICOSANOID_LIGAND_BINDING_RECEPTORS Genes involved in Eicosanoid ligand-binding receptors
0.1 1.1 REACTOME_PECAM1_INTERACTIONS Genes involved in PECAM1 interactions
0.1 1.4 REACTOME_CITRIC_ACID_CYCLE_TCA_CYCLE Genes involved in Citric acid cycle (TCA cycle)
0.1 1.1 REACTOME_DESTABILIZATION_OF_MRNA_BY_TRISTETRAPROLIN_TTP Genes involved in Destabilization of mRNA by Tristetraprolin (TTP)
0.1 0.6 REACTOME_VIRAL_MESSENGER_RNA_SYNTHESIS Genes involved in Viral Messenger RNA Synthesis
0.1 1.1 REACTOME_RNA_POL_III_CHAIN_ELONGATION Genes involved in RNA Polymerase III Chain Elongation
0.0 2.2 REACTOME_NCAM1_INTERACTIONS Genes involved in NCAM1 interactions
0.0 0.5 REACTOME_P53_DEPENDENT_G1_DNA_DAMAGE_RESPONSE Genes involved in p53-Dependent G1 DNA Damage Response
0.0 2.6 REACTOME_APC_C_CDH1_MEDIATED_DEGRADATION_OF_CDC20_AND_OTHER_APC_C_CDH1_TARGETED_PROTEINS_IN_LATE_MITOSIS_EARLY_G1 Genes involved in APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1
0.0 0.1 REACTOME_METABOLISM_OF_STEROID_HORMONES_AND_VITAMINS_A_AND_D Genes involved in Metabolism of steroid hormones and vitamins A and D
0.0 0.5 REACTOME_ADVANCED_GLYCOSYLATION_ENDPRODUCT_RECEPTOR_SIGNALING Genes involved in Advanced glycosylation endproduct receptor signaling
0.0 0.9 REACTOME_OTHER_SEMAPHORIN_INTERACTIONS Genes involved in Other semaphorin interactions
0.0 1.5 REACTOME_COLLAGEN_FORMATION Genes involved in Collagen formation
0.0 2.8 REACTOME_NRAGE_SIGNALS_DEATH_THROUGH_JNK Genes involved in NRAGE signals death through JNK
0.0 0.3 REACTOME_CYTOCHROME_P450_ARRANGED_BY_SUBSTRATE_TYPE Genes involved in Cytochrome P450 - arranged by substrate type
0.0 1.7 REACTOME_DEPOSITION_OF_NEW_CENPA_CONTAINING_NUCLEOSOMES_AT_THE_CENTROMERE Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere
0.0 0.4 REACTOME_SYNTHESIS_OF_PIPS_AT_THE_EARLY_ENDOSOME_MEMBRANE Genes involved in Synthesis of PIPs at the early endosome membrane
0.0 0.3 REACTOME_DESTABILIZATION_OF_MRNA_BY_AUF1_HNRNP_D0 Genes involved in Destabilization of mRNA by AUF1 (hnRNP D0)
0.0 1.9 REACTOME_PPARA_ACTIVATES_GENE_EXPRESSION Genes involved in PPARA Activates Gene Expression
0.0 0.8 REACTOME_REGULATION_OF_BETA_CELL_DEVELOPMENT Genes involved in Regulation of beta-cell development
0.0 0.6 REACTOME_SYNTHESIS_AND_INTERCONVERSION_OF_NUCLEOTIDE_DI_AND_TRIPHOSPHATES Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.0 0.5 REACTOME_RAS_ACTIVATION_UOPN_CA2_INFUX_THROUGH_NMDA_RECEPTOR Genes involved in Ras activation uopn Ca2+ infux through NMDA receptor
0.0 0.8 REACTOME_ION_TRANSPORT_BY_P_TYPE_ATPASES Genes involved in Ion transport by P-type ATPases
0.0 0.8 REACTOME_MRNA_3_END_PROCESSING Genes involved in mRNA 3'-end processing
0.0 3.0 REACTOME_ANTIGEN_PROCESSING_UBIQUITINATION_PROTEASOME_DEGRADATION Genes involved in Antigen processing: Ubiquitination & Proteasome degradation
0.0 0.6 REACTOME_AMINO_ACID_TRANSPORT_ACROSS_THE_PLASMA_MEMBRANE Genes involved in Amino acid transport across the plasma membrane
0.0 0.4 REACTOME_PEROXISOMAL_LIPID_METABOLISM Genes involved in Peroxisomal lipid metabolism
0.0 0.5 REACTOME_O_LINKED_GLYCOSYLATION_OF_MUCINS Genes involved in O-linked glycosylation of mucins
0.0 0.1 REACTOME_PASSIVE_TRANSPORT_BY_AQUAPORINS Genes involved in Passive Transport by Aquaporins
0.0 0.2 REACTOME_MEIOTIC_RECOMBINATION Genes involved in Meiotic Recombination
0.0 0.2 REACTOME_MITOCHONDRIAL_TRNA_AMINOACYLATION Genes involved in Mitochondrial tRNA aminoacylation