Motif ID: Insm1

Z-value: 0.326


Transcription factors associated with Insm1:

Gene SymbolEntrez IDGene Name
Insm1 ENSMUSG00000068154.4 Insm1

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Insm1mm10_v2_chr2_+_146221921_146221921-0.192.6e-01Click!


Activity profile for motif Insm1.

activity profile for motif Insm1


Sorted Z-values histogram for motif Insm1

Sorted Z-values for motif Insm1



Network of associatons between targets according to the STRING database.



First level regulatory network of Insm1

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.
View svg image
View png image

Top targets:


Showing 1 to 20 of 121 entries
PromoterScoreRefseqGene SymbolGene Name
chr16_-_67620880 1.265 ENSMUST00000114292.1
ENSMUST00000120898.1
 Cadm2

cell adhesion molecule 2

chr16_-_67620805 1.110 ENSMUST00000120594.1
 Cadm2
cell adhesion molecule 2
chr3_+_117575268 1.052 ENSMUST00000039564.6
 4833424O15Rik
RIKEN cDNA 4833424O15 gene
chr19_+_8664005 1.004 ENSMUST00000035444.3
ENSMUST00000163785.1
 Chrm1

cholinergic receptor, muscarinic 1, CNS

chr3_+_117575227 1.002 ENSMUST00000106473.2
 4833424O15Rik
RIKEN cDNA 4833424O15 gene
chr7_+_5057161 0.929 ENSMUST00000045543.5
 Ccdc106
coiled-coil domain containing 106
chrX_+_9199865 0.918 ENSMUST00000069763.2
 Lancl3
LanC lantibiotic synthetase component C-like 3 (bacterial)
chr13_+_16011851 0.864 ENSMUST00000042603.6
 Inhba
inhibin beta-A
chr12_-_12940600 0.797 ENSMUST00000130990.1
 Mycn
v-myc myelocytomatosis viral related oncogene, neuroblastoma derived (avian)
chrX_+_99975570 0.778 ENSMUST00000113779.1
ENSMUST00000113776.1
ENSMUST00000113775.1
ENSMUST00000113780.1
ENSMUST00000113778.1
ENSMUST00000113781.1
ENSMUST00000113783.1
ENSMUST00000071453.2
ENSMUST00000113777.1
 Eda








ectodysplasin-A








chr7_+_5056706 0.760 ENSMUST00000144802.1
 Ccdc106
coiled-coil domain containing 106
chr12_-_70111920 0.743 ENSMUST00000169074.1
ENSMUST00000021468.7
 Nin

ninein

chr12_+_51593315 0.692 ENSMUST00000164782.2
ENSMUST00000085412.5
 Coch

coagulation factor C homolog (Limulus polyphemus)

chr17_+_47688992 0.618 ENSMUST00000156118.1
 Frs3
fibroblast growth factor receptor substrate 3
chr12_+_95692212 0.572 ENSMUST00000057324.3
 Flrt2
fibronectin leucine rich transmembrane protein 2
chr14_-_55116935 0.565 ENSMUST00000022819.5
 Jph4
junctophilin 4
chr2_+_26583858 0.557 ENSMUST00000100290.5
ENSMUST00000102907.5
 Egfl7

EGF-like domain 7

chr10_-_116473875 0.516 ENSMUST00000068233.4
 Kcnmb4
potassium large conductance calcium-activated channel, subfamily M, beta member 4
chr3_-_73056943 0.507 ENSMUST00000059407.7
 Slitrk3
SLIT and NTRK-like family, member 3
chr7_+_78578830 0.503 ENSMUST00000064591.4
 Gm9885
predicted gene 9885

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 40 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 2.4 GO:0007157 heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0007157)
0.2 1.0 GO:0007197 adenylate cyclase-inhibiting G-protein coupled acetylcholine receptor signaling pathway(GO:0007197) phospholipase C-activating G-protein coupled acetylcholine receptor signaling pathway(GO:0007207)
0.1 1.0 GO:0005513 detection of calcium ion(GO:0005513)
0.2 0.9 GO:0042636 negative regulation of hair cycle(GO:0042636) progesterone secretion(GO:0042701) negative regulation of hair follicle development(GO:0051799) positive regulation of ovulation(GO:0060279)
0.3 0.8 GO:0061153 trachea submucosa development(GO:0061152) trachea gland development(GO:0061153)
0.1 0.8 GO:0034638 phosphatidylcholine catabolic process(GO:0034638)
0.1 0.8 GO:0045607 regulation of auditory receptor cell differentiation(GO:0045607) regulation of mechanoreceptor differentiation(GO:0045631) regulation of inner ear receptor cell differentiation(GO:2000980)
0.2 0.7 GO:1904049 negative regulation of spontaneous neurotransmitter secretion(GO:1904049)
0.1 0.7 GO:0034454 microtubule anchoring at centrosome(GO:0034454)
0.0 0.6 GO:2001256 regulation of store-operated calcium entry(GO:2001256)
0.0 0.6 GO:0071711 basement membrane organization(GO:0071711)
0.2 0.5 GO:0099547 regulation of translation at synapse, modulating synaptic transmission(GO:0099547) regulation of translation at postsynapse, modulating synaptic transmission(GO:0099578) positive regulation of intracellular transport of viral material(GO:1901254)
0.1 0.5 GO:0097491 trigeminal nerve morphogenesis(GO:0021636) trigeminal nerve structural organization(GO:0021637) trunk segmentation(GO:0035290) trunk neural crest cell migration(GO:0036484) ventral trunk neural crest cell migration(GO:0036486) sympathetic neuron projection extension(GO:0097490) sympathetic neuron projection guidance(GO:0097491) semaphorin-plexin signaling pathway involved in axon guidance(GO:1902287)
0.1 0.5 GO:0070127 tRNA aminoacylation for mitochondrial protein translation(GO:0070127)
0.1 0.5 GO:0001574 ganglioside biosynthetic process(GO:0001574)
0.1 0.4 GO:0045347 negative regulation of MHC class II biosynthetic process(GO:0045347)
0.1 0.4 GO:0036072 intramembranous ossification(GO:0001957) direct ossification(GO:0036072)
0.1 0.4 GO:0097264 self proteolysis(GO:0097264)
0.0 0.4 GO:2000096 segment specification(GO:0007379) positive regulation of Wnt signaling pathway, planar cell polarity pathway(GO:2000096)
0.0 0.4 GO:0032011 ARF protein signal transduction(GO:0032011) regulation of ARF protein signal transduction(GO:0032012)

Gene overrepresentation in cellular_component category:

Showing 1 to 16 of 16 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 2.4 GO:0032809 neuronal cell body membrane(GO:0032809)
0.0 1.0 GO:0032279 asymmetric synapse(GO:0032279)
0.3 0.9 GO:0043512 inhibin A complex(GO:0043512)
0.1 0.7 GO:0036449 microtubule minus-end(GO:0036449)
0.1 0.7 GO:1990761 growth cone lamellipodium(GO:1990761)
0.1 0.6 GO:0030314 junctional membrane complex(GO:0030314)
0.2 0.5 GO:1990812 growth cone filopodium(GO:1990812)
0.1 0.4 GO:0031428 box C/D snoRNP complex(GO:0031428)
0.0 0.4 GO:0034707 chloride channel complex(GO:0034707)
0.1 0.3 GO:0033010 paranodal junction(GO:0033010)
0.0 0.3 GO:0005742 mitochondrial outer membrane translocase complex(GO:0005742)
0.1 0.2 GO:0070436 Grb2-EGFR complex(GO:0070436)
0.0 0.2 GO:0005890 sodium:potassium-exchanging ATPase complex(GO:0005890)
0.0 0.1 GO:0097444 spine apparatus(GO:0097444)
0.0 0.1 GO:0070826 paraferritin complex(GO:0070826)
0.0 0.1 GO:0008180 COP9 signalosome(GO:0008180)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 30 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.2 1.0 GO:0016907 G-protein coupled acetylcholine receptor activity(GO:0016907)
0.1 1.0 GO:0045499 chemorepellent activity(GO:0045499)
0.1 1.0 GO:0015269 calcium-activated potassium channel activity(GO:0015269)
0.1 0.9 GO:0070699 type II activin receptor binding(GO:0070699)
0.2 0.8 GO:0004528 phosphodiesterase I activity(GO:0004528)
0.0 0.8 GO:0005164 tumor necrosis factor receptor binding(GO:0005164)
0.0 0.7 GO:0005104 fibroblast growth factor receptor binding(GO:0005104)
0.0 0.7 GO:0008157 protein phosphatase 1 binding(GO:0008157)
0.0 0.6 GO:0005112 Notch binding(GO:0005112)
0.1 0.5 GO:0033592 RNA strand annealing activity(GO:0033592)
0.1 0.5 GO:0001665 alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity(GO:0001665)
0.1 0.4 GO:0034511 U3 snoRNA binding(GO:0034511)
0.1 0.4 GO:0051525 NFAT protein binding(GO:0051525)
0.0 0.4 GO:0070679 inositol 1,4,5 trisphosphate binding(GO:0070679)
0.0 0.4 GO:0032794 GTPase activating protein binding(GO:0032794)
0.0 0.4 GO:0097602 cullin family protein binding(GO:0097602)
0.1 0.3 GO:0034739 histone deacetylase activity (H4-K16 specific)(GO:0034739) tubulin deacetylase activity(GO:0042903)
0.0 0.3 GO:0015288 porin activity(GO:0015288)
0.0 0.3 GO:0005247 voltage-gated chloride channel activity(GO:0005247)
0.0 0.2 GO:0008449 N-acetylglucosamine-6-sulfatase activity(GO:0008449)

Gene overrepresentation in C2:CP category:

Showing 1 to 6 of 6 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 0.9 PID_ALK1_PATHWAY ALK1 signaling events
0.0 0.5 ST_TUMOR_NECROSIS_FACTOR_PATHWAY Tumor Necrosis Factor Pathway.
0.0 0.4 PID_ARF_3PATHWAY Arf1 pathway
0.0 0.3 ST_WNT_CA2_CYCLIC_GMP_PATHWAY Wnt/Ca2+/cyclic GMP signaling.
0.0 0.3 PID_HDAC_CLASSIII_PATHWAY Signaling events mediated by HDAC Class III
0.0 0.2 PID_IL5_PATHWAY IL5-mediated signaling events

Gene overrepresentation in C2:CP:REACTOME category:

Showing 1 to 8 of 8 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 2.4 REACTOME_ADHERENS_JUNCTIONS_INTERACTIONS Genes involved in Adherens junctions interactions
0.1 1.0 REACTOME_AMINE_LIGAND_BINDING_RECEPTORS Genes involved in Amine ligand-binding receptors
0.0 1.0 REACTOME_CGMP_EFFECTS Genes involved in cGMP effects
0.2 0.9 REACTOME_GLYCOPROTEIN_HORMONES Genes involved in Glycoprotein hormones
0.0 0.9 REACTOME_FRS2_MEDIATED_CASCADE Genes involved in FRS2-mediated cascade
0.0 0.5 REACTOME_MITOCHONDRIAL_TRNA_AMINOACYLATION Genes involved in Mitochondrial tRNA aminoacylation
0.0 0.4 REACTOME_RIP_MEDIATED_NFKB_ACTIVATION_VIA_DAI Genes involved in RIP-mediated NFkB activation via DAI
0.0 0.2 REACTOME_KERATAN_SULFATE_DEGRADATION Genes involved in Keratan sulfate degradation