Motif ID: Irf2_Irf1_Irf8_Irf9_Irf7
Z-value: 3.355
Transcription factors associated with Irf2_Irf1_Irf8_Irf9_Irf7:
| Gene Symbol | Entrez ID | Gene Name |
|---|---|---|
| Irf1 | ENSMUSG00000018899.10 | Irf1 |
| Irf2 | ENSMUSG00000031627.7 | Irf2 |
| Irf7 | ENSMUSG00000025498.8 | Irf7 |
| Irf8 | ENSMUSG00000041515.3 | Irf8 |
| Irf9 | ENSMUSG00000002325.8 | Irf9 |
Activity-expression correlation:
| Gene Symbol | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| Irf1 | mm10_v2_chr11_+_53770458_53770509 | 0.56 | 3.3e-04 | Click! |
| Irf2 | mm10_v2_chr8_+_46739745_46739791 | 0.54 | 5.9e-04 | Click! |
| Irf8 | mm10_v2_chr8_+_120736352_120736385 | 0.45 | 4.9e-03 | Click! |
| Irf7 | mm10_v2_chr7_-_141266415_141266481 | 0.22 | 1.8e-01 | Click! |
| Irf9 | mm10_v2_chr14_+_55604550_55604579 | 0.14 | 4.1e-01 | Click! |
Top targets:
Gene overrepresentation in biological_process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 5.3 | 21.2 | GO:0060332 | positive regulation of response to interferon-gamma(GO:0060332) positive regulation of interferon-gamma-mediated signaling pathway(GO:0060335) |
| 4.6 | 13.9 | GO:0045349 | interferon-alpha biosynthetic process(GO:0045349) regulation of interferon-alpha biosynthetic process(GO:0045354) |
| 3.4 | 10.1 | GO:0002302 | CD8-positive, alpha-beta T cell differentiation involved in immune response(GO:0002302) |
| 3.0 | 9.1 | GO:1904139 | microglial cell migration(GO:1904124) regulation of microglial cell migration(GO:1904139) |
| 2.6 | 7.9 | GO:0001580 | detection of chemical stimulus involved in sensory perception of bitter taste(GO:0001580) |
| 2.4 | 14.5 | GO:0060330 | regulation of response to interferon-gamma(GO:0060330) |
| 2.3 | 9.2 | GO:0044565 | dendritic cell proliferation(GO:0044565) |
| 2.3 | 13.7 | GO:0032196 | regulation of transposition(GO:0010528) negative regulation of transposition(GO:0010529) transposition(GO:0032196) |
| 2.2 | 8.8 | GO:0034759 | regulation of iron ion transport(GO:0034756) regulation of iron ion transmembrane transport(GO:0034759) |
| 2.1 | 10.6 | GO:0035547 | interferon-beta secretion(GO:0035546) regulation of interferon-beta secretion(GO:0035547) positive regulation of interferon-beta secretion(GO:0035549) |
| 1.8 | 7.1 | GO:0070269 | pyroptosis(GO:0070269) |
| 1.6 | 12.6 | GO:0080184 | response to stilbenoid(GO:0035634) response to phenylpropanoid(GO:0080184) |
| 1.5 | 26.0 | GO:2001275 | positive regulation of glucose import in response to insulin stimulus(GO:2001275) |
| 1.5 | 4.4 | GO:0099547 | regulation of translation at synapse, modulating synaptic transmission(GO:0099547) regulation of translation at postsynapse, modulating synaptic transmission(GO:0099578) positive regulation of intracellular transport of viral material(GO:1901254) |
| 1.2 | 2.3 | GO:0060809 | mesodermal to mesenchymal transition involved in gastrulation(GO:0060809) |
| 1.1 | 3.4 | GO:0050713 | negative regulation of interleukin-1 beta secretion(GO:0050713) |
| 1.1 | 5.3 | GO:1900170 | negative regulation of glucocorticoid mediated signaling pathway(GO:1900170) |
| 1.0 | 8.4 | GO:0048625 | myoblast fate commitment(GO:0048625) |
| 1.0 | 4.2 | GO:0002484 | antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway(GO:0002484) antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent(GO:0002485) |
| 0.9 | 2.8 | GO:0006553 | lysine metabolic process(GO:0006553) |
| 0.9 | 7.5 | GO:0032020 | ISG15-protein conjugation(GO:0032020) |
| 0.9 | 4.6 | GO:0034421 | post-translational protein acetylation(GO:0034421) |
| 0.9 | 30.2 | GO:0035458 | cellular response to interferon-beta(GO:0035458) |
| 0.9 | 9.7 | GO:2000051 | negative regulation of non-canonical Wnt signaling pathway(GO:2000051) |
| 0.9 | 2.6 | GO:0051754 | meiotic sister chromatid cohesion, centromeric(GO:0051754) |
| 0.9 | 6.9 | GO:0090336 | positive regulation of brown fat cell differentiation(GO:0090336) |
| 0.9 | 2.6 | GO:0008065 | establishment of blood-nerve barrier(GO:0008065) regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion(GO:0014809) |
| 0.9 | 2.6 | GO:0048687 | positive regulation of sprouting of injured axon(GO:0048687) positive regulation of axon extension involved in regeneration(GO:0048691) |
| 0.9 | 6.0 | GO:0043569 | negative regulation of insulin-like growth factor receptor signaling pathway(GO:0043569) |
| 0.8 | 0.8 | GO:2000564 | antigen processing and presentation of endogenous peptide antigen via MHC class Ib via ER pathway(GO:0002488) antigen processing and presentation of endogenous peptide antigen via MHC class Ib via ER pathway, TAP-dependent(GO:0002489) CD8-positive, alpha-beta T cell proliferation(GO:0035740) regulation of CD8-positive, alpha-beta T cell proliferation(GO:2000564) |
| 0.8 | 8.9 | GO:1902036 | regulation of hematopoietic stem cell differentiation(GO:1902036) |
| 0.8 | 24.7 | GO:0032728 | positive regulation of interferon-beta production(GO:0032728) |
| 0.7 | 12.7 | GO:0021684 | cerebellar granular layer formation(GO:0021684) cerebellar granule cell differentiation(GO:0021707) |
| 0.7 | 2.0 | GO:0060364 | frontal suture morphogenesis(GO:0060364) |
| 0.6 | 3.2 | GO:0070460 | thyroid-stimulating hormone secretion(GO:0070460) |
| 0.6 | 1.8 | GO:0014891 | striated muscle atrophy(GO:0014891) |
| 0.6 | 3.7 | GO:0002606 | positive regulation of dendritic cell antigen processing and presentation(GO:0002606) |
| 0.6 | 1.8 | GO:1903225 | negative regulation of endodermal cell differentiation(GO:1903225) |
| 0.6 | 10.8 | GO:0046597 | negative regulation of viral entry into host cell(GO:0046597) |
| 0.6 | 1.7 | GO:2000508 | regulation of dendritic cell chemotaxis(GO:2000508) |
| 0.6 | 2.8 | GO:0007089 | traversing start control point of mitotic cell cycle(GO:0007089) |
| 0.6 | 1.1 | GO:0003274 | endocardial cushion fusion(GO:0003274) |
| 0.5 | 1.6 | GO:0097350 | neutrophil clearance(GO:0097350) |
| 0.5 | 1.6 | GO:1902915 | negative regulation of protein import into nucleus, translocation(GO:0033159) negative regulation of protein K63-linked ubiquitination(GO:1900045) negative regulation of protein polyubiquitination(GO:1902915) |
| 0.5 | 2.1 | GO:0030091 | protein repair(GO:0030091) |
| 0.5 | 3.1 | GO:0003383 | apical constriction(GO:0003383) |
| 0.5 | 2.1 | GO:2001045 | closure of optic fissure(GO:0061386) negative regulation of integrin-mediated signaling pathway(GO:2001045) |
| 0.5 | 1.5 | GO:0042097 | interleukin-4 biosynthetic process(GO:0042097) regulation of interleukin-4 biosynthetic process(GO:0045402) |
| 0.5 | 1.5 | GO:0097309 | cap1 mRNA methylation(GO:0097309) |
| 0.5 | 2.0 | GO:1903237 | negative regulation of leukocyte tethering or rolling(GO:1903237) |
| 0.5 | 1.5 | GO:0042196 | dichloromethane metabolic process(GO:0018900) chlorinated hydrocarbon metabolic process(GO:0042196) halogenated hydrocarbon metabolic process(GO:0042197) |
| 0.5 | 2.4 | GO:0019885 | antigen processing and presentation of endogenous peptide antigen via MHC class I(GO:0019885) |
| 0.5 | 1.4 | GO:0070944 | neutrophil mediated killing of bacterium(GO:0070944) |
| 0.5 | 0.9 | GO:2000481 | positive regulation of cAMP-dependent protein kinase activity(GO:2000481) |
| 0.5 | 0.5 | GO:0071639 | positive regulation of monocyte chemotactic protein-1 production(GO:0071639) |
| 0.4 | 3.5 | GO:0090091 | positive regulation of extracellular matrix disassembly(GO:0090091) |
| 0.4 | 2.9 | GO:0010032 | meiotic chromosome condensation(GO:0010032) |
| 0.4 | 1.8 | GO:0035989 | tendon development(GO:0035989) |
| 0.4 | 1.1 | GO:0035359 | negative regulation of peroxisome proliferator activated receptor signaling pathway(GO:0035359) |
| 0.4 | 1.1 | GO:0019441 | tryptophan catabolic process(GO:0006569) tryptophan catabolic process to kynurenine(GO:0019441) quinolinate biosynthetic process(GO:0019805) indole-containing compound catabolic process(GO:0042436) indolalkylamine catabolic process(GO:0046218) kynurenine metabolic process(GO:0070189) |
| 0.3 | 3.0 | GO:0051151 | negative regulation of smooth muscle cell differentiation(GO:0051151) |
| 0.3 | 1.0 | GO:0032621 | interleukin-18 production(GO:0032621) |
| 0.3 | 3.5 | GO:2000741 | positive regulation of mesenchymal stem cell differentiation(GO:2000741) |
| 0.3 | 0.9 | GO:0071211 | protein targeting to vacuole involved in autophagy(GO:0071211) |
| 0.3 | 1.2 | GO:0006982 | response to lipid hydroperoxide(GO:0006982) cellular response to lipid hydroperoxide(GO:0071449) |
| 0.3 | 0.9 | GO:0090272 | negative regulation of fibroblast growth factor production(GO:0090272) |
| 0.3 | 0.9 | GO:0006533 | aspartate catabolic process(GO:0006533) D-amino acid metabolic process(GO:0046416) |
| 0.3 | 1.2 | GO:1901098 | positive regulation of autophagosome maturation(GO:1901098) |
| 0.3 | 3.3 | GO:0042572 | retinol metabolic process(GO:0042572) |
| 0.3 | 0.6 | GO:0051771 | negative regulation of nitric-oxide synthase biosynthetic process(GO:0051771) |
| 0.3 | 1.2 | GO:0015889 | cobalamin transport(GO:0015889) |
| 0.3 | 1.2 | GO:0032901 | positive regulation of neurotrophin production(GO:0032901) |
| 0.3 | 2.0 | GO:0070779 | D-aspartate transport(GO:0070777) D-aspartate import(GO:0070779) |
| 0.3 | 0.8 | GO:0009814 | defense response, incompatible interaction(GO:0009814) |
| 0.3 | 1.9 | GO:0051611 | negative regulation of neurotransmitter uptake(GO:0051581) serotonin uptake(GO:0051610) regulation of serotonin uptake(GO:0051611) negative regulation of serotonin uptake(GO:0051612) |
| 0.3 | 0.5 | GO:0072223 | metanephric glomerular mesangium development(GO:0072223) metanephric glomerular mesangial cell proliferation involved in metanephros development(GO:0072262) |
| 0.3 | 1.1 | GO:0006447 | regulation of translational initiation by iron(GO:0006447) positive regulation of translational initiation by iron(GO:0045994) |
| 0.3 | 1.1 | GO:1903416 | negative regulation of vitamin D biosynthetic process(GO:0010957) negative regulation of vitamin metabolic process(GO:0046137) regulation of calcidiol 1-monooxygenase activity(GO:0060558) positive regulation of hyaluronan biosynthetic process(GO:1900127) response to glycoside(GO:1903416) |
| 0.3 | 2.6 | GO:1902083 | negative regulation of peptidyl-cysteine S-nitrosylation(GO:1902083) |
| 0.3 | 2.0 | GO:0032876 | negative regulation of DNA endoreduplication(GO:0032876) |
| 0.3 | 3.1 | GO:0042832 | defense response to protozoan(GO:0042832) |
| 0.3 | 0.8 | GO:0044778 | meiotic DNA integrity checkpoint(GO:0044778) |
| 0.2 | 0.2 | GO:1901668 | regulation of superoxide dismutase activity(GO:1901668) |
| 0.2 | 1.0 | GO:1903463 | regulation of mitotic cell cycle DNA replication(GO:1903463) |
| 0.2 | 0.7 | GO:0072092 | ureteric bud invasion(GO:0072092) |
| 0.2 | 1.4 | GO:0032483 | regulation of Rab protein signal transduction(GO:0032483) |
| 0.2 | 6.0 | GO:0002474 | antigen processing and presentation of peptide antigen via MHC class I(GO:0002474) |
| 0.2 | 9.9 | GO:0046825 | regulation of protein export from nucleus(GO:0046825) |
| 0.2 | 0.9 | GO:0046947 | hydroxylysine metabolic process(GO:0046946) hydroxylysine biosynthetic process(GO:0046947) |
| 0.2 | 0.7 | GO:0071360 | cellular response to exogenous dsRNA(GO:0071360) |
| 0.2 | 1.5 | GO:2000348 | regulation of CD40 signaling pathway(GO:2000348) |
| 0.2 | 3.2 | GO:0042759 | long-chain fatty acid biosynthetic process(GO:0042759) |
| 0.2 | 1.7 | GO:1901162 | serotonin biosynthetic process(GO:0042427) primary amino compound biosynthetic process(GO:1901162) |
| 0.2 | 1.1 | GO:0045213 | neurotransmitter receptor metabolic process(GO:0045213) |
| 0.2 | 1.8 | GO:1903608 | protein localization to cytoplasmic stress granule(GO:1903608) |
| 0.2 | 0.6 | GO:1902202 | regulation of hepatocyte growth factor receptor signaling pathway(GO:1902202) |
| 0.2 | 0.2 | GO:0010847 | regulation of chromatin assembly(GO:0010847) |
| 0.2 | 0.9 | GO:0035878 | nail development(GO:0035878) |
| 0.2 | 0.7 | GO:1902340 | telomeric heterochromatin assembly(GO:0031509) negative regulation of chromosome condensation(GO:1902340) |
| 0.2 | 0.5 | GO:0019085 | early viral transcription(GO:0019085) |
| 0.2 | 1.5 | GO:0032836 | glomerular basement membrane development(GO:0032836) |
| 0.2 | 10.4 | GO:0006940 | regulation of smooth muscle contraction(GO:0006940) |
| 0.2 | 1.6 | GO:2000781 | positive regulation of double-strand break repair(GO:2000781) |
| 0.2 | 0.5 | GO:0043456 | regulation of pentose-phosphate shunt(GO:0043456) |
| 0.2 | 1.1 | GO:0046292 | formaldehyde metabolic process(GO:0046292) |
| 0.2 | 0.7 | GO:0010991 | negative regulation of SMAD protein complex assembly(GO:0010991) |
| 0.2 | 0.8 | GO:0003406 | retinal pigment epithelium development(GO:0003406) |
| 0.2 | 0.8 | GO:0070494 | regulation of thrombin receptor signaling pathway(GO:0070494) negative regulation of thrombin receptor signaling pathway(GO:0070495) |
| 0.2 | 0.5 | GO:1904569 | regulation of selenocysteine incorporation(GO:1904569) |
| 0.2 | 0.2 | GO:0000821 | regulation of arginine metabolic process(GO:0000821) |
| 0.2 | 0.5 | GO:0038018 | Wnt receptor catabolic process(GO:0038018) |
| 0.1 | 0.6 | GO:0010992 | ubiquitin homeostasis(GO:0010992) |
| 0.1 | 0.7 | GO:0046501 | protoporphyrinogen IX metabolic process(GO:0046501) |
| 0.1 | 0.6 | GO:0045918 | negative regulation of cytolysis(GO:0045918) |
| 0.1 | 0.4 | GO:0032497 | detection of lipopolysaccharide(GO:0032497) |
| 0.1 | 2.0 | GO:0034497 | protein localization to pre-autophagosomal structure(GO:0034497) |
| 0.1 | 1.3 | GO:0035269 | protein O-linked mannosylation(GO:0035269) |
| 0.1 | 1.4 | GO:0019368 | fatty acid elongation, saturated fatty acid(GO:0019367) fatty acid elongation, unsaturated fatty acid(GO:0019368) fatty acid elongation, monounsaturated fatty acid(GO:0034625) fatty acid elongation, polyunsaturated fatty acid(GO:0034626) |
| 0.1 | 2.4 | GO:0045292 | mRNA cis splicing, via spliceosome(GO:0045292) |
| 0.1 | 0.8 | GO:1900029 | positive regulation of ruffle assembly(GO:1900029) |
| 0.1 | 1.0 | GO:0036462 | TRAIL-activated apoptotic signaling pathway(GO:0036462) |
| 0.1 | 0.5 | GO:0046598 | positive regulation of viral entry into host cell(GO:0046598) negative regulation of protein deubiquitination(GO:0090086) |
| 0.1 | 1.0 | GO:0042769 | DNA damage response, detection of DNA damage(GO:0042769) |
| 0.1 | 0.4 | GO:1904879 | positive regulation of calcium ion transmembrane transport via high voltage-gated calcium channel(GO:1904879) |
| 0.1 | 0.6 | GO:0090310 | negative regulation of methylation-dependent chromatin silencing(GO:0090310) |
| 0.1 | 0.7 | GO:0006108 | malate metabolic process(GO:0006108) |
| 0.1 | 0.4 | GO:2000383 | regulation of ectoderm development(GO:2000383) negative regulation of ectoderm development(GO:2000384) |
| 0.1 | 5.2 | GO:0010390 | histone monoubiquitination(GO:0010390) |
| 0.1 | 0.4 | GO:0048698 | negative regulation of collateral sprouting in absence of injury(GO:0048698) |
| 0.1 | 0.6 | GO:1902965 | regulation of protein localization to early endosome(GO:1902965) positive regulation of protein localization to early endosome(GO:1902966) |
| 0.1 | 0.8 | GO:0010587 | miRNA catabolic process(GO:0010587) |
| 0.1 | 0.6 | GO:0051026 | chiasma assembly(GO:0051026) |
| 0.1 | 0.2 | GO:0002314 | germinal center B cell differentiation(GO:0002314) |
| 0.1 | 0.6 | GO:0090669 | snoRNA guided rRNA pseudouridine synthesis(GO:0000454) telomerase RNA stabilization(GO:0090669) |
| 0.1 | 1.0 | GO:0006930 | substrate-dependent cell migration, cell extension(GO:0006930) |
| 0.1 | 2.1 | GO:0035855 | megakaryocyte development(GO:0035855) |
| 0.1 | 0.2 | GO:0002765 | immune response-inhibiting signal transduction(GO:0002765) |
| 0.1 | 2.5 | GO:0071108 | protein K48-linked deubiquitination(GO:0071108) |
| 0.1 | 0.8 | GO:0009072 | aromatic amino acid family metabolic process(GO:0009072) |
| 0.1 | 1.0 | GO:0072189 | ureter development(GO:0072189) |
| 0.1 | 0.6 | GO:0042795 | snRNA transcription from RNA polymerase II promoter(GO:0042795) |
| 0.1 | 0.5 | GO:0045654 | positive regulation of megakaryocyte differentiation(GO:0045654) |
| 0.1 | 0.2 | GO:0001951 | intestinal D-glucose absorption(GO:0001951) terminal web assembly(GO:1902896) |
| 0.1 | 0.3 | GO:0051342 | regulation of cyclic-nucleotide phosphodiesterase activity(GO:0051342) negative regulation of cyclic-nucleotide phosphodiesterase activity(GO:0051344) |
| 0.1 | 0.3 | GO:0045113 | integrin biosynthetic process(GO:0045112) regulation of integrin biosynthetic process(GO:0045113) |
| 0.1 | 0.8 | GO:0072602 | interleukin-4 secretion(GO:0072602) |
| 0.1 | 0.8 | GO:0002347 | response to tumor cell(GO:0002347) |
| 0.1 | 0.7 | GO:0042574 | isoprenoid catabolic process(GO:0008300) retinal metabolic process(GO:0042574) |
| 0.1 | 0.2 | GO:0045073 | chemokine biosynthetic process(GO:0042033) regulation of chemokine biosynthetic process(GO:0045073) positive regulation of chemokine biosynthetic process(GO:0045080) chemokine metabolic process(GO:0050755) |
| 0.1 | 0.5 | GO:0036337 | Fas signaling pathway(GO:0036337) |
| 0.1 | 0.7 | GO:0097475 | motor neuron migration(GO:0097475) |
| 0.1 | 1.4 | GO:0000188 | inactivation of MAPK activity(GO:0000188) |
| 0.1 | 0.9 | GO:0090503 | RNA phosphodiester bond hydrolysis, exonucleolytic(GO:0090503) |
| 0.1 | 0.9 | GO:0045779 | negative regulation of bone resorption(GO:0045779) |
| 0.1 | 0.6 | GO:0031293 | membrane protein intracellular domain proteolysis(GO:0031293) |
| 0.1 | 0.5 | GO:0044375 | regulation of peroxisome size(GO:0044375) |
| 0.1 | 0.2 | GO:1903588 | negative regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis(GO:1903588) |
| 0.1 | 0.4 | GO:0006048 | glucosamine metabolic process(GO:0006041) UDP-N-acetylglucosamine biosynthetic process(GO:0006048) |
| 0.1 | 8.1 | GO:0007286 | spermatid development(GO:0007286) |
| 0.1 | 0.6 | GO:2000194 | regulation of female gonad development(GO:2000194) |
| 0.1 | 0.3 | GO:2000561 | CD4-positive, alpha-beta T cell proliferation(GO:0035739) regulation of CD4-positive, alpha-beta T cell proliferation(GO:2000561) |
| 0.1 | 1.4 | GO:0038092 | nodal signaling pathway(GO:0038092) |
| 0.1 | 0.3 | GO:1902261 | positive regulation of delayed rectifier potassium channel activity(GO:1902261) |
| 0.1 | 0.7 | GO:0031274 | positive regulation of pseudopodium assembly(GO:0031274) |
| 0.1 | 0.6 | GO:1902902 | negative regulation of autophagosome assembly(GO:1902902) |
| 0.1 | 0.4 | GO:0061502 | early endosome to recycling endosome transport(GO:0061502) |
| 0.1 | 0.7 | GO:0051307 | meiotic chromosome separation(GO:0051307) |
| 0.1 | 1.0 | GO:0036297 | interstrand cross-link repair(GO:0036297) |
| 0.1 | 1.4 | GO:0097150 | neuronal stem cell population maintenance(GO:0097150) |
| 0.1 | 2.5 | GO:0035019 | somatic stem cell population maintenance(GO:0035019) |
| 0.1 | 0.5 | GO:0071763 | nuclear membrane organization(GO:0071763) |
| 0.1 | 0.7 | GO:1904262 | negative regulation of TORC1 signaling(GO:1904262) |
| 0.1 | 0.2 | GO:0072015 | glomerular visceral epithelial cell development(GO:0072015) glomerular epithelial cell development(GO:0072310) |
| 0.1 | 0.5 | GO:0019227 | neuronal action potential propagation(GO:0019227) action potential propagation(GO:0098870) |
| 0.1 | 2.7 | GO:0042632 | cholesterol homeostasis(GO:0042632) sterol homeostasis(GO:0055092) |
| 0.0 | 0.4 | GO:0072010 | renal filtration cell differentiation(GO:0061318) glomerular epithelium development(GO:0072010) glomerular visceral epithelial cell differentiation(GO:0072112) glomerular epithelial cell differentiation(GO:0072311) |
| 0.0 | 0.4 | GO:0031953 | negative regulation of protein autophosphorylation(GO:0031953) |
| 0.0 | 0.7 | GO:0033234 | negative regulation of protein sumoylation(GO:0033234) |
| 0.0 | 0.7 | GO:0010447 | response to acidic pH(GO:0010447) |
| 0.0 | 0.1 | GO:0070212 | protein poly-ADP-ribosylation(GO:0070212) |
| 0.0 | 0.6 | GO:2000096 | positive regulation of Wnt signaling pathway, planar cell polarity pathway(GO:2000096) |
| 0.0 | 0.6 | GO:1990403 | embryonic brain development(GO:1990403) |
| 0.0 | 0.3 | GO:0060576 | intestinal epithelial cell development(GO:0060576) |
| 0.0 | 0.9 | GO:1901522 | positive regulation of transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus(GO:1901522) |
| 0.0 | 0.3 | GO:0001672 | regulation of chromatin assembly or disassembly(GO:0001672) |
| 0.0 | 1.4 | GO:0006336 | DNA replication-independent nucleosome assembly(GO:0006336) |
| 0.0 | 0.8 | GO:0050434 | positive regulation of viral transcription(GO:0050434) |
| 0.0 | 0.7 | GO:0007194 | negative regulation of adenylate cyclase activity(GO:0007194) |
| 0.0 | 0.5 | GO:0030033 | microvillus assembly(GO:0030033) |
| 0.0 | 0.2 | GO:0051096 | regulation of helicase activity(GO:0051095) positive regulation of helicase activity(GO:0051096) |
| 0.0 | 1.2 | GO:0090162 | establishment of epithelial cell polarity(GO:0090162) |
| 0.0 | 0.3 | GO:0090003 | regulation of Golgi to plasma membrane protein transport(GO:0042996) regulation of establishment of protein localization to plasma membrane(GO:0090003) |
| 0.0 | 1.1 | GO:0031365 | N-terminal protein amino acid modification(GO:0031365) |
| 0.0 | 0.3 | GO:0031584 | activation of phospholipase D activity(GO:0031584) |
| 0.0 | 0.7 | GO:0007340 | acrosome reaction(GO:0007340) |
| 0.0 | 1.2 | GO:0051642 | centrosome localization(GO:0051642) |
| 0.0 | 0.5 | GO:0000183 | chromatin silencing at rDNA(GO:0000183) |
| 0.0 | 0.3 | GO:0051457 | maintenance of protein location in nucleus(GO:0051457) |
| 0.0 | 0.4 | GO:0001963 | synaptic transmission, dopaminergic(GO:0001963) |
| 0.0 | 0.5 | GO:0007064 | mitotic sister chromatid cohesion(GO:0007064) |
| 0.0 | 0.2 | GO:0060613 | fat pad development(GO:0060613) |
| 0.0 | 0.4 | GO:0070932 | histone H3 deacetylation(GO:0070932) |
| 0.0 | 1.1 | GO:0001919 | regulation of receptor recycling(GO:0001919) |
| 0.0 | 0.1 | GO:1903147 | negative regulation of mitophagy(GO:1903147) |
| 0.0 | 0.4 | GO:0034453 | microtubule anchoring(GO:0034453) |
| 0.0 | 0.3 | GO:0006007 | glucose catabolic process(GO:0006007) |
| 0.0 | 0.2 | GO:2000381 | negative regulation of mesoderm development(GO:2000381) |
| 0.0 | 1.4 | GO:0006749 | glutathione metabolic process(GO:0006749) |
| 0.0 | 0.2 | GO:0048251 | elastic fiber assembly(GO:0048251) |
| 0.0 | 0.1 | GO:1902626 | mature ribosome assembly(GO:0042256) assembly of large subunit precursor of preribosome(GO:1902626) |
| 0.0 | 0.2 | GO:0006104 | succinyl-CoA metabolic process(GO:0006104) |
| 0.0 | 0.4 | GO:0046718 | viral entry into host cell(GO:0046718) |
| 0.0 | 0.9 | GO:0006270 | DNA replication initiation(GO:0006270) |
| 0.0 | 0.6 | GO:0032467 | positive regulation of cytokinesis(GO:0032467) |
| 0.0 | 0.3 | GO:0019884 | antigen processing and presentation of exogenous antigen(GO:0019884) |
| 0.0 | 0.4 | GO:0043984 | histone H4-K16 acetylation(GO:0043984) |
| 0.0 | 0.3 | GO:0016180 | snRNA processing(GO:0016180) |
| 0.0 | 1.0 | GO:0071347 | cellular response to interleukin-1(GO:0071347) |
| 0.0 | 1.1 | GO:0080171 | lysosome organization(GO:0007040) lytic vacuole organization(GO:0080171) |
| 0.0 | 1.7 | GO:0010811 | positive regulation of cell-substrate adhesion(GO:0010811) |
| 0.0 | 0.1 | GO:0050882 | voluntary musculoskeletal movement(GO:0050882) |
| 0.0 | 0.4 | GO:0051570 | regulation of histone H3-K9 methylation(GO:0051570) |
| 0.0 | 0.5 | GO:0046677 | response to antibiotic(GO:0046677) |
| 0.0 | 0.2 | GO:0036159 | outer dynein arm assembly(GO:0036158) inner dynein arm assembly(GO:0036159) |
| 0.0 | 0.1 | GO:0043653 | mitochondrial fragmentation involved in apoptotic process(GO:0043653) |
| 0.0 | 0.1 | GO:0006968 | cellular defense response(GO:0006968) |
| 0.0 | 0.0 | GO:0021852 | pyramidal neuron migration(GO:0021852) |
| 0.0 | 2.1 | GO:0008360 | regulation of cell shape(GO:0008360) |
| 0.0 | 0.0 | GO:0060842 | arterial endothelial cell differentiation(GO:0060842) |
| 0.0 | 0.9 | GO:0000271 | polysaccharide biosynthetic process(GO:0000271) |
| 0.0 | 0.2 | GO:0048009 | insulin-like growth factor receptor signaling pathway(GO:0048009) |
| 0.0 | 0.3 | GO:0090200 | positive regulation of release of cytochrome c from mitochondria(GO:0090200) |
| 0.0 | 0.0 | GO:0060762 | regulation of branching involved in mammary gland duct morphogenesis(GO:0060762) |
| 0.0 | 0.1 | GO:0048852 | diencephalon morphogenesis(GO:0048852) |
| 0.0 | 0.2 | GO:0032460 | negative regulation of protein oligomerization(GO:0032460) negative regulation of protein homooligomerization(GO:0032463) |
| 0.0 | 0.0 | GO:0048793 | pronephros development(GO:0048793) |
| 0.0 | 0.0 | GO:0032815 | negative regulation of natural killer cell activation(GO:0032815) |
Gene overrepresentation in cellular_component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 3.0 | 9.0 | GO:1990682 | CSF1-CSF1R complex(GO:1990682) |
| 1.8 | 7.1 | GO:0061702 | inflammasome complex(GO:0061702) |
| 1.7 | 20.6 | GO:0042612 | MHC class I protein complex(GO:0042612) |
| 1.3 | 18.9 | GO:0044754 | autolysosome(GO:0044754) |
| 1.2 | 10.4 | GO:0030478 | actin cap(GO:0030478) |
| 1.1 | 4.4 | GO:1902737 | viral replication complex(GO:0019034) dendritic filopodium(GO:1902737) |
| 0.9 | 8.4 | GO:0070369 | beta-catenin-TCF7L2 complex(GO:0070369) |
| 0.8 | 3.1 | GO:0031084 | BLOC-2 complex(GO:0031084) |
| 0.7 | 4.2 | GO:0042406 | extrinsic component of endoplasmic reticulum membrane(GO:0042406) |
| 0.6 | 1.8 | GO:0005588 | collagen type V trimer(GO:0005588) |
| 0.5 | 8.3 | GO:0005614 | interstitial matrix(GO:0005614) |
| 0.4 | 3.1 | GO:0033269 | internode region of axon(GO:0033269) |
| 0.4 | 4.6 | GO:0031618 | nuclear pericentric heterochromatin(GO:0031618) |
| 0.4 | 1.4 | GO:0097447 | dendritic tree(GO:0097447) |
| 0.3 | 1.7 | GO:0043020 | NADPH oxidase complex(GO:0043020) |
| 0.3 | 2.0 | GO:0031265 | CD95 death-inducing signaling complex(GO:0031265) |
| 0.3 | 1.0 | GO:0097058 | CRLF-CLCF1 complex(GO:0097058) |
| 0.3 | 2.9 | GO:0000796 | condensin complex(GO:0000796) |
| 0.3 | 1.5 | GO:0005587 | collagen type IV trimer(GO:0005587) network-forming collagen trimer(GO:0098642) collagen network(GO:0098645) basement membrane collagen trimer(GO:0098651) |
| 0.3 | 3.7 | GO:0020003 | symbiont-containing vacuole(GO:0020003) |
| 0.3 | 0.3 | GO:0030868 | smooth endoplasmic reticulum membrane(GO:0030868) smooth endoplasmic reticulum part(GO:0097425) |
| 0.3 | 1.4 | GO:1990462 | omegasome(GO:1990462) |
| 0.3 | 3.2 | GO:0000778 | condensed nuclear chromosome kinetochore(GO:0000778) |
| 0.2 | 1.0 | GO:0044307 | dendritic branch(GO:0044307) |
| 0.2 | 1.8 | GO:0097165 | nuclear stress granule(GO:0097165) |
| 0.2 | 10.7 | GO:0005788 | endoplasmic reticulum lumen(GO:0005788) |
| 0.2 | 3.1 | GO:0042788 | polysomal ribosome(GO:0042788) |
| 0.2 | 1.6 | GO:0043657 | host(GO:0018995) host cell part(GO:0033643) host cell(GO:0043657) |
| 0.2 | 22.6 | GO:0016363 | nuclear matrix(GO:0016363) |
| 0.2 | 1.8 | GO:0098643 | fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643) |
| 0.2 | 0.9 | GO:1990357 | terminal web(GO:1990357) |
| 0.2 | 1.0 | GO:0070531 | BRCA1-A complex(GO:0070531) |
| 0.2 | 0.7 | GO:0002111 | BRCA2-BRAF35 complex(GO:0002111) |
| 0.2 | 1.3 | GO:0001520 | outer dense fiber(GO:0001520) |
| 0.2 | 3.9 | GO:0030285 | integral component of synaptic vesicle membrane(GO:0030285) intrinsic component of synaptic vesicle membrane(GO:0098563) |
| 0.2 | 0.6 | GO:0033185 | dolichol-phosphate-mannose synthase complex(GO:0033185) |
| 0.2 | 6.2 | GO:0005637 | nuclear inner membrane(GO:0005637) |
| 0.2 | 1.1 | GO:0033256 | I-kappaB/NF-kappaB complex(GO:0033256) |
| 0.1 | 0.6 | GO:0090661 | box H/ACA telomerase RNP complex(GO:0090661) |
| 0.1 | 1.7 | GO:0034045 | pre-autophagosomal structure membrane(GO:0034045) |
| 0.1 | 0.5 | GO:0008537 | proteasome activator complex(GO:0008537) |
| 0.1 | 0.5 | GO:0065010 | extracellular membrane-bounded organelle(GO:0065010) |
| 0.1 | 0.8 | GO:0030896 | checkpoint clamp complex(GO:0030896) |
| 0.1 | 0.6 | GO:0071556 | integral component of cytoplasmic side of endoplasmic reticulum membrane(GO:0071458) integral component of lumenal side of endoplasmic reticulum membrane(GO:0071556) lumenal side of endoplasmic reticulum membrane(GO:0098553) |
| 0.1 | 2.6 | GO:0031527 | filopodium membrane(GO:0031527) |
| 0.1 | 0.7 | GO:0031465 | Cul4B-RING E3 ubiquitin ligase complex(GO:0031465) |
| 0.1 | 4.2 | GO:0016235 | aggresome(GO:0016235) |
| 0.1 | 6.6 | GO:0031519 | PcG protein complex(GO:0031519) |
| 0.1 | 1.1 | GO:0043083 | synaptic cleft(GO:0043083) |
| 0.1 | 0.9 | GO:0005640 | nuclear outer membrane(GO:0005640) |
| 0.1 | 1.0 | GO:0070419 | nonhomologous end joining complex(GO:0070419) |
| 0.1 | 1.2 | GO:0005922 | connexon complex(GO:0005922) |
| 0.1 | 0.7 | GO:0033270 | paranode region of axon(GO:0033270) |
| 0.1 | 0.6 | GO:0030915 | Smc5-Smc6 complex(GO:0030915) |
| 0.1 | 3.0 | GO:0030673 | axolemma(GO:0030673) |
| 0.1 | 1.1 | GO:0031616 | spindle pole centrosome(GO:0031616) |
| 0.1 | 0.4 | GO:0072487 | MSL complex(GO:0072487) |
| 0.1 | 0.4 | GO:0046696 | lipopolysaccharide receptor complex(GO:0046696) |
| 0.1 | 0.4 | GO:0045298 | tubulin complex(GO:0045298) |
| 0.1 | 1.3 | GO:0031010 | ISWI-type complex(GO:0031010) |
| 0.1 | 0.4 | GO:0035749 | myelin sheath adaxonal region(GO:0035749) |
| 0.1 | 0.6 | GO:0031362 | anchored component of external side of plasma membrane(GO:0031362) |
| 0.1 | 1.0 | GO:0042555 | MCM complex(GO:0042555) |
| 0.1 | 0.3 | GO:0034751 | aryl hydrocarbon receptor complex(GO:0034751) |
| 0.1 | 0.8 | GO:0031209 | SCAR complex(GO:0031209) |
| 0.1 | 3.1 | GO:0000307 | cyclin-dependent protein kinase holoenzyme complex(GO:0000307) |
| 0.1 | 8.1 | GO:0005923 | bicellular tight junction(GO:0005923) |
| 0.1 | 0.4 | GO:0071203 | WASH complex(GO:0071203) |
| 0.0 | 0.2 | GO:1990130 | Iml1 complex(GO:1990130) |
| 0.0 | 0.3 | GO:0097197 | tetraspanin-enriched microdomain(GO:0097197) |
| 0.0 | 1.7 | GO:0016592 | mediator complex(GO:0016592) |
| 0.0 | 0.6 | GO:0031597 | cytosolic proteasome complex(GO:0031597) |
| 0.0 | 0.6 | GO:0017119 | Golgi transport complex(GO:0017119) |
| 0.0 | 0.6 | GO:0051286 | cell tip(GO:0051286) |
| 0.0 | 2.5 | GO:0005776 | autophagosome(GO:0005776) |
| 0.0 | 2.7 | GO:0031463 | Cul3-RING ubiquitin ligase complex(GO:0031463) |
| 0.0 | 0.4 | GO:1990454 | L-type voltage-gated calcium channel complex(GO:1990454) |
| 0.0 | 0.5 | GO:0010369 | chromocenter(GO:0010369) |
| 0.0 | 1.3 | GO:0008023 | transcription elongation factor complex(GO:0008023) |
| 0.0 | 1.3 | GO:0009925 | basal plasma membrane(GO:0009925) |
| 0.0 | 0.1 | GO:0060293 | P granule(GO:0043186) pole plasm(GO:0045495) germ plasm(GO:0060293) |
| 0.0 | 1.0 | GO:0030665 | clathrin-coated vesicle membrane(GO:0030665) |
| 0.0 | 0.8 | GO:0005689 | U12-type spliceosomal complex(GO:0005689) |
| 0.0 | 0.4 | GO:0031588 | nucleotide-activated protein kinase complex(GO:0031588) |
| 0.0 | 0.1 | GO:0005638 | lamin filament(GO:0005638) |
| 0.0 | 1.1 | GO:0031901 | early endosome membrane(GO:0031901) |
| 0.0 | 0.3 | GO:0036038 | MKS complex(GO:0036038) |
| 0.0 | 0.2 | GO:0045252 | oxoglutarate dehydrogenase complex(GO:0045252) |
| 0.0 | 0.3 | GO:0032039 | integrator complex(GO:0032039) |
| 0.0 | 0.5 | GO:0005779 | integral component of peroxisomal membrane(GO:0005779) |
| 0.0 | 318.4 | GO:0005575 | cellular_component(GO:0005575) |
Gene overrepresentation in molecular_function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 3.4 | 13.7 | GO:0047844 | deoxycytidine deaminase activity(GO:0047844) |
| 1.6 | 4.8 | GO:0016160 | alpha-amylase activity(GO:0004556) amylase activity(GO:0016160) |
| 1.3 | 5.3 | GO:0038049 | glucocorticoid receptor activity(GO:0004883) transcription factor activity, ligand-activated RNA polymerase II transcription factor binding(GO:0038049) glucocorticoid-activated RNA polymerase II transcription factor binding transcription factor activity(GO:0038051) |
| 1.3 | 5.1 | GO:0004694 | eukaryotic translation initiation factor 2alpha kinase activity(GO:0004694) |
| 1.2 | 3.7 | GO:0098770 | FBXO family protein binding(GO:0098770) |
| 1.1 | 3.4 | GO:0070052 | collagen V binding(GO:0070052) |
| 1.1 | 5.7 | GO:0050700 | CARD domain binding(GO:0050700) |
| 0.9 | 0.9 | GO:0003953 | NAD+ nucleosidase activity(GO:0003953) |
| 0.8 | 17.7 | GO:0003950 | NAD+ ADP-ribosyltransferase activity(GO:0003950) |
| 0.8 | 10.8 | GO:0030881 | beta-2-microglobulin binding(GO:0030881) |
| 0.8 | 5.5 | GO:1901612 | phosphatidylglycerol binding(GO:1901611) cardiolipin binding(GO:1901612) |
| 0.8 | 2.3 | GO:0005110 | frizzled-2 binding(GO:0005110) |
| 0.8 | 4.6 | GO:0004468 | lysine N-acetyltransferase activity, acting on acetyl phosphate as donor(GO:0004468) |
| 0.7 | 5.0 | GO:0052650 | NADP-retinol dehydrogenase activity(GO:0052650) |
| 0.7 | 2.8 | GO:0016647 | oxidoreductase activity, acting on the CH-NH group of donors, oxygen as acceptor(GO:0016647) |
| 0.6 | 2.4 | GO:0003844 | 1,4-alpha-glucan branching enzyme activity(GO:0003844) |
| 0.6 | 5.4 | GO:0034046 | poly(G) binding(GO:0034046) |
| 0.6 | 1.7 | GO:0004510 | tryptophan 5-monooxygenase activity(GO:0004510) |
| 0.5 | 1.5 | GO:0019120 | hydrolase activity, acting on acid halide bonds(GO:0016824) hydrolase activity, acting on acid halide bonds, in C-halide compounds(GO:0019120) alkylhalidase activity(GO:0047651) |
| 0.5 | 1.8 | GO:0046920 | alpha-(1->3)-fucosyltransferase activity(GO:0046920) |
| 0.4 | 1.7 | GO:0016175 | superoxide-generating NADPH oxidase activity(GO:0016175) |
| 0.4 | 3.4 | GO:0005138 | interleukin-6 receptor binding(GO:0005138) |
| 0.4 | 3.8 | GO:0038062 | protein tyrosine kinase collagen receptor activity(GO:0038062) |
| 0.4 | 2.1 | GO:0072542 | protein phosphatase activator activity(GO:0072542) |
| 0.4 | 1.6 | GO:0072345 | NAADP-sensitive calcium-release channel activity(GO:0072345) |
| 0.4 | 5.3 | GO:0031386 | protein tag(GO:0031386) |
| 0.4 | 3.2 | GO:0019911 | structural constituent of myelin sheath(GO:0019911) |
| 0.4 | 8.4 | GO:0045295 | gamma-catenin binding(GO:0045295) |
| 0.4 | 1.5 | GO:0004483 | mRNA (nucleoside-2'-O-)-methyltransferase activity(GO:0004483) |
| 0.4 | 1.1 | GO:0008392 | arachidonic acid epoxygenase activity(GO:0008392) |
| 0.4 | 1.1 | GO:0016174 | NAD(P)H oxidase activity(GO:0016174) |
| 0.3 | 2.1 | GO:0033743 | peptide-methionine (R)-S-oxide reductase activity(GO:0033743) |
| 0.3 | 2.0 | GO:0015501 | glutamate:sodium symporter activity(GO:0015501) |
| 0.3 | 7.5 | GO:0005521 | lamin binding(GO:0005521) |
| 0.3 | 1.0 | GO:0004022 | alcohol dehydrogenase (NAD) activity(GO:0004022) |
| 0.3 | 1.6 | GO:0005030 | neurotrophin receptor activity(GO:0005030) |
| 0.3 | 24.1 | GO:0019843 | rRNA binding(GO:0019843) |
| 0.3 | 0.9 | GO:0004534 | 5'-3' exoribonuclease activity(GO:0004534) |
| 0.3 | 0.8 | GO:0001716 | L-amino-acid oxidase activity(GO:0001716) |
| 0.3 | 54.4 | GO:0001078 | transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078) |
| 0.3 | 1.1 | GO:0034714 | type III transforming growth factor beta receptor binding(GO:0034714) |
| 0.3 | 1.1 | GO:0070644 | vitamin D response element binding(GO:0070644) |
| 0.2 | 0.7 | GO:0004473 | malic enzyme activity(GO:0004470) malate dehydrogenase (decarboxylating) (NAD+) activity(GO:0004471) malate dehydrogenase (decarboxylating) (NADP+) activity(GO:0004473) |
| 0.2 | 2.1 | GO:0008329 | signaling pattern recognition receptor activity(GO:0008329) pattern recognition receptor activity(GO:0038187) |
| 0.2 | 0.9 | GO:0008475 | procollagen-lysine 5-dioxygenase activity(GO:0008475) |
| 0.2 | 0.9 | GO:0004030 | aldehyde dehydrogenase [NAD(P)+] activity(GO:0004030) |
| 0.2 | 3.2 | GO:0017128 | phospholipid scramblase activity(GO:0017128) |
| 0.2 | 0.8 | GO:0051378 | serotonin binding(GO:0051378) |
| 0.2 | 1.2 | GO:0048403 | brain-derived neurotrophic factor binding(GO:0048403) |
| 0.2 | 0.8 | GO:0005008 | hepatocyte growth factor-activated receptor activity(GO:0005008) |
| 0.2 | 1.7 | GO:0031730 | CCR5 chemokine receptor binding(GO:0031730) |
| 0.2 | 0.6 | GO:0005171 | hepatocyte growth factor receptor binding(GO:0005171) |
| 0.2 | 14.2 | GO:0003725 | double-stranded RNA binding(GO:0003725) |
| 0.2 | 1.1 | GO:0004886 | 9-cis retinoic acid receptor activity(GO:0004886) |
| 0.2 | 2.5 | GO:0017166 | vinculin binding(GO:0017166) |
| 0.2 | 0.7 | GO:0035877 | death effector domain binding(GO:0035877) |
| 0.2 | 10.0 | GO:0001102 | RNA polymerase II activating transcription factor binding(GO:0001102) |
| 0.2 | 0.7 | GO:0019863 | IgG receptor activity(GO:0019770) IgE binding(GO:0019863) |
| 0.2 | 1.2 | GO:0031419 | cobalamin binding(GO:0031419) |
| 0.2 | 0.5 | GO:0048019 | receptor antagonist activity(GO:0048019) |
| 0.2 | 1.0 | GO:0035312 | 5'-3' exodeoxyribonuclease activity(GO:0035312) |
| 0.2 | 1.8 | GO:0005123 | death receptor binding(GO:0005123) |
| 0.2 | 0.8 | GO:0050265 | RNA uridylyltransferase activity(GO:0050265) |
| 0.2 | 0.5 | GO:0046538 | bisphosphoglycerate mutase activity(GO:0004082) phosphoglycerate mutase activity(GO:0004619) 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase activity(GO:0046538) |
| 0.2 | 0.6 | GO:0004582 | dolichyl-phosphate beta-D-mannosyltransferase activity(GO:0004582) |
| 0.2 | 0.6 | GO:0008853 | exodeoxyribonuclease III activity(GO:0008853) |
| 0.2 | 1.1 | GO:0004971 | AMPA glutamate receptor activity(GO:0004971) |
| 0.2 | 7.7 | GO:0016836 | hydro-lyase activity(GO:0016836) |
| 0.1 | 1.6 | GO:0032036 | myosin heavy chain binding(GO:0032036) |
| 0.1 | 6.8 | GO:0032266 | phosphatidylinositol-3-phosphate binding(GO:0032266) |
| 0.1 | 2.6 | GO:0004435 | phosphatidylinositol phospholipase C activity(GO:0004435) |
| 0.1 | 5.1 | GO:0005201 | extracellular matrix structural constituent(GO:0005201) |
| 0.1 | 15.1 | GO:0036459 | thiol-dependent ubiquitinyl hydrolase activity(GO:0036459) ubiquitinyl hydrolase activity(GO:0101005) |
| 0.1 | 2.2 | GO:1904264 | ubiquitin protein ligase activity involved in ERAD pathway(GO:1904264) |
| 0.1 | 2.6 | GO:0048020 | CCR chemokine receptor binding(GO:0048020) |
| 0.1 | 0.5 | GO:0004035 | alkaline phosphatase activity(GO:0004035) |
| 0.1 | 1.4 | GO:0009922 | fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338) |
| 0.1 | 0.6 | GO:0004661 | protein geranylgeranyltransferase activity(GO:0004661) |
| 0.1 | 0.5 | GO:0016812 | hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides(GO:0016812) |
| 0.1 | 0.5 | GO:0004999 | vasoactive intestinal polypeptide receptor activity(GO:0004999) |
| 0.1 | 0.6 | GO:0004839 | ubiquitin activating enzyme activity(GO:0004839) |
| 0.1 | 0.5 | GO:0038085 | vascular endothelial growth factor binding(GO:0038085) |
| 0.1 | 0.3 | GO:0031752 | D5 dopamine receptor binding(GO:0031752) |
| 0.1 | 10.1 | GO:0008083 | growth factor activity(GO:0008083) |
| 0.1 | 0.6 | GO:0070579 | methylcytosine dioxygenase activity(GO:0070579) |
| 0.1 | 0.3 | GO:0036004 | GAF domain binding(GO:0036004) |
| 0.1 | 0.9 | GO:0005540 | hyaluronic acid binding(GO:0005540) |
| 0.1 | 2.0 | GO:0034237 | protein kinase A regulatory subunit binding(GO:0034237) |
| 0.1 | 1.2 | GO:0050431 | transforming growth factor beta binding(GO:0050431) |
| 0.1 | 8.9 | GO:0046332 | SMAD binding(GO:0046332) |
| 0.1 | 0.6 | GO:0042296 | ISG15 transferase activity(GO:0042296) |
| 0.1 | 0.9 | GO:0016641 | oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor(GO:0016641) |
| 0.1 | 0.8 | GO:0042608 | T cell receptor binding(GO:0042608) |
| 0.1 | 0.3 | GO:0005118 | sevenless binding(GO:0005118) |
| 0.1 | 0.9 | GO:0004679 | AMP-activated protein kinase activity(GO:0004679) |
| 0.1 | 2.5 | GO:0070182 | DNA polymerase binding(GO:0070182) |
| 0.1 | 0.6 | GO:0034513 | box H/ACA snoRNA binding(GO:0034513) |
| 0.1 | 1.5 | GO:0001848 | complement binding(GO:0001848) |
| 0.1 | 0.6 | GO:0042500 | aspartic endopeptidase activity, intramembrane cleaving(GO:0042500) |
| 0.1 | 1.0 | GO:0005149 | interleukin-1 receptor binding(GO:0005149) |
| 0.1 | 0.7 | GO:0016634 | oxidoreductase activity, acting on the CH-CH group of donors, oxygen as acceptor(GO:0016634) |
| 0.1 | 0.5 | GO:0097322 | 7SK snRNA binding(GO:0097322) |
| 0.1 | 0.4 | GO:0086056 | voltage-gated calcium channel activity involved in AV node cell action potential(GO:0086056) |
| 0.1 | 1.1 | GO:0045499 | chemorepellent activity(GO:0045499) |
| 0.1 | 1.0 | GO:0004559 | alpha-mannosidase activity(GO:0004559) |
| 0.1 | 0.5 | GO:0035368 | selenocysteine insertion sequence binding(GO:0035368) |
| 0.1 | 1.8 | GO:1990841 | promoter-specific chromatin binding(GO:1990841) |
| 0.1 | 1.5 | GO:0043394 | proteoglycan binding(GO:0043394) |
| 0.1 | 1.7 | GO:0035035 | histone acetyltransferase binding(GO:0035035) |
| 0.1 | 2.1 | GO:0017091 | AU-rich element binding(GO:0017091) |
| 0.1 | 1.6 | GO:0070064 | proline-rich region binding(GO:0070064) |
| 0.1 | 1.2 | GO:0004602 | glutathione peroxidase activity(GO:0004602) |
| 0.1 | 0.7 | GO:0016701 | oxidoreductase activity, acting on single donors with incorporation of molecular oxygen(GO:0016701) oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen(GO:0016702) |
| 0.1 | 0.9 | GO:0032813 | tumor necrosis factor receptor superfamily binding(GO:0032813) |
| 0.1 | 0.6 | GO:0005247 | voltage-gated chloride channel activity(GO:0005247) |
| 0.1 | 1.7 | GO:0071889 | 14-3-3 protein binding(GO:0071889) |
| 0.1 | 0.5 | GO:0008656 | cysteine-type endopeptidase activator activity involved in apoptotic process(GO:0008656) |
| 0.1 | 20.5 | GO:0001228 | transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001228) |
| 0.0 | 1.1 | GO:0005159 | insulin-like growth factor receptor binding(GO:0005159) |
| 0.0 | 0.7 | GO:0000400 | four-way junction DNA binding(GO:0000400) |
| 0.0 | 2.0 | GO:0003730 | mRNA 3'-UTR binding(GO:0003730) |
| 0.0 | 0.5 | GO:0044548 | S100 protein binding(GO:0044548) |
| 0.0 | 0.3 | GO:0097157 | pre-mRNA intronic binding(GO:0097157) |
| 0.0 | 0.1 | GO:0043559 | insulin binding(GO:0043559) |
| 0.0 | 12.4 | GO:0003924 | GTPase activity(GO:0003924) |
| 0.0 | 3.7 | GO:0042826 | histone deacetylase binding(GO:0042826) |
| 0.0 | 0.6 | GO:0008484 | sulfuric ester hydrolase activity(GO:0008484) |
| 0.0 | 0.2 | GO:0034602 | oxoglutarate dehydrogenase (NAD+) activity(GO:0034602) |
| 0.0 | 1.5 | GO:0031492 | nucleosomal DNA binding(GO:0031492) |
| 0.0 | 0.2 | GO:0004528 | phosphodiesterase I activity(GO:0004528) NADH pyrophosphatase activity(GO:0035529) |
| 0.0 | 0.3 | GO:0061133 | endopeptidase activator activity(GO:0061133) |
| 0.0 | 4.9 | GO:0042393 | histone binding(GO:0042393) |
| 0.0 | 0.2 | GO:0004920 | interleukin-10 receptor activity(GO:0004920) |
| 0.0 | 1.6 | GO:0030374 | ligand-dependent nuclear receptor transcription coactivator activity(GO:0030374) |
| 0.0 | 0.3 | GO:0032454 | histone demethylase activity (H3-K9 specific)(GO:0032454) |
| 0.0 | 0.7 | GO:0017049 | GTP-Rho binding(GO:0017049) |
| 0.0 | 9.9 | GO:0003712 | transcription cofactor activity(GO:0003712) |
| 0.0 | 0.5 | GO:0070300 | phosphatidic acid binding(GO:0070300) |
| 0.0 | 0.4 | GO:0005528 | macrolide binding(GO:0005527) FK506 binding(GO:0005528) |
| 0.0 | 0.3 | GO:0017160 | Ral GTPase binding(GO:0017160) |
| 0.0 | 0.9 | GO:0005484 | SNAP receptor activity(GO:0005484) |
| 0.0 | 0.0 | GO:0030337 | DNA polymerase processivity factor activity(GO:0030337) |
| 0.0 | 0.1 | GO:0001609 | G-protein coupled adenosine receptor activity(GO:0001609) |
| 0.0 | 0.6 | GO:0051539 | 4 iron, 4 sulfur cluster binding(GO:0051539) |
| 0.0 | 0.1 | GO:0046703 | natural killer cell lectin-like receptor binding(GO:0046703) |
| 0.0 | 0.2 | GO:0043325 | phosphatidylinositol-3,4-bisphosphate binding(GO:0043325) |
| 0.0 | 7.0 | GO:0004842 | ubiquitin-protein transferase activity(GO:0004842) |
| 0.0 | 0.3 | GO:0004198 | calcium-dependent cysteine-type endopeptidase activity(GO:0004198) |
| 0.0 | 0.6 | GO:0005179 | hormone activity(GO:0005179) |
| 0.0 | 0.3 | GO:0050136 | NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136) |
| 0.0 | 0.1 | GO:0034987 | immunoglobulin receptor binding(GO:0034987) |
| 0.0 | 0.3 | GO:0005158 | insulin receptor binding(GO:0005158) |
| 0.0 | 0.2 | GO:0004596 | peptide alpha-N-acetyltransferase activity(GO:0004596) |
| 0.0 | 0.4 | GO:0008080 | N-acetyltransferase activity(GO:0008080) |
Gene overrepresentation in C2:CP category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.5 | 5.2 | SA_MMP_CYTOKINE_CONNECTION | Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix. |
| 0.3 | 18.1 | PID_IL12_2PATHWAY | IL12-mediated signaling events |
| 0.2 | 3.7 | PID_IL2_STAT5_PATHWAY | IL2 signaling events mediated by STAT5 |
| 0.1 | 6.3 | NABA_COLLAGENS | Genes encoding collagen proteins |
| 0.1 | 3.0 | PID_PI3KCI_AKT_PATHWAY | Class I PI3K signaling events mediated by Akt |
| 0.1 | 1.1 | PID_ERBB_NETWORK_PATHWAY | ErbB receptor signaling network |
| 0.1 | 1.2 | SA_FAS_SIGNALING | The TNF-type receptor Fas induces apoptosis on ligand binding. |
| 0.1 | 3.4 | PID_MYC_PATHWAY | C-MYC pathway |
| 0.1 | 1.0 | SA_G2_AND_M_PHASES | Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition. |
| 0.1 | 0.8 | ST_PHOSPHOINOSITIDE_3_KINASE_PATHWAY | PI3K Pathway |
| 0.1 | 5.1 | PID_HNF3B_PATHWAY | FOXA2 and FOXA3 transcription factor networks |
| 0.1 | 6.5 | PID_TCPTP_PATHWAY | Signaling events mediated by TCPTP |
| 0.1 | 3.3 | PID_SHP2_PATHWAY | SHP2 signaling |
| 0.1 | 2.3 | PID_FOXM1_PATHWAY | FOXM1 transcription factor network |
| 0.1 | 5.5 | PID_PLK1_PATHWAY | PLK1 signaling events |
| 0.1 | 8.4 | SIG_PIP3_SIGNALING_IN_CARDIAC_MYOCTES | Genes related to PIP3 signaling in cardiac myocytes |
| 0.1 | 1.9 | PID_E2F_PATHWAY | E2F transcription factor network |
| 0.1 | 4.8 | PID_AP1_PATHWAY | AP-1 transcription factor network |
| 0.1 | 0.8 | PID_CD40_PATHWAY | CD40/CD40L signaling |
| 0.1 | 1.1 | PID_INTEGRIN3_PATHWAY | Beta3 integrin cell surface interactions |
| 0.1 | 2.1 | NABA_PROTEOGLYCANS | Genes encoding proteoglycans |
| 0.1 | 2.1 | PID_RXR_VDR_PATHWAY | RXR and RAR heterodimerization with other nuclear receptor |
| 0.1 | 1.0 | PID_HNF3A_PATHWAY | FOXA1 transcription factor network |
| 0.1 | 0.5 | SA_PROGRAMMED_CELL_DEATH | Programmed cell death, or apoptosis, eliminates damaged or unneeded cells. |
| 0.1 | 1.0 | NABA_BASEMENT_MEMBRANES | Genes encoding structural components of basement membranes |
| 0.1 | 1.6 | PID_DELTA_NP63_PATHWAY | Validated transcriptional targets of deltaNp63 isoforms |
| 0.1 | 1.6 | PID_ATR_PATHWAY | ATR signaling pathway |
| 0.0 | 1.0 | PID_SYNDECAN_4_PATHWAY | Syndecan-4-mediated signaling events |
| 0.0 | 1.5 | PID_ECADHERIN_STABILIZATION_PATHWAY | Stabilization and expansion of the E-cadherin adherens junction |
| 0.0 | 1.8 | PID_TAP63_PATHWAY | Validated transcriptional targets of TAp63 isoforms |
| 0.0 | 2.1 | PID_RAC1_PATHWAY | RAC1 signaling pathway |
| 0.0 | 1.7 | PID_WNT_NONCANONICAL_PATHWAY | Noncanonical Wnt signaling pathway |
| 0.0 | 1.0 | PID_NFAT_TFPATHWAY | Calcineurin-regulated NFAT-dependent transcription in lymphocytes |
| 0.0 | 1.0 | PID_AURORA_A_PATHWAY | Aurora A signaling |
| 0.0 | 0.3 | PID_THROMBIN_PAR4_PATHWAY | PAR4-mediated thrombin signaling events |
| 0.0 | 0.7 | PID_TOLL_ENDOGENOUS_PATHWAY | Endogenous TLR signaling |
| 0.0 | 0.6 | PID_P38_ALPHA_BETA_PATHWAY | Regulation of p38-alpha and p38-beta |
| 0.0 | 0.8 | PID_RHOA_PATHWAY | RhoA signaling pathway |
| 0.0 | 3.6 | NABA_ECM_GLYCOPROTEINS | Genes encoding structural ECM glycoproteins |
| 0.0 | 0.5 | PID_ARF6_PATHWAY | Arf6 signaling events |
| 0.0 | 1.2 | PID_HEDGEHOG_GLI_PATHWAY | Hedgehog signaling events mediated by Gli proteins |
| 0.0 | 1.1 | PID_P73PATHWAY | p73 transcription factor network |
| 0.0 | 0.9 | ST_FAS_SIGNALING_PATHWAY | Fas Signaling Pathway |
| 0.0 | 2.6 | NABA_ECM_REGULATORS | Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix |
| 0.0 | 0.2 | PID_AMB2_NEUTROPHILS_PATHWAY | amb2 Integrin signaling |
| 0.0 | 0.2 | PID_TRAIL_PATHWAY | TRAIL signaling pathway |
| 0.0 | 0.4 | PID_FCER1_PATHWAY | Fc-epsilon receptor I signaling in mast cells |
| 0.0 | 0.7 | PID_VEGFR1_2_PATHWAY | Signaling events mediated by VEGFR1 and VEGFR2 |
| 0.0 | 0.4 | PID_AURORA_B_PATHWAY | Aurora B signaling |
Gene overrepresentation in C2:CP:REACTOME category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 2.9 | 8.7 | REACTOME_ENDOSOMAL_VACUOLAR_PATHWAY | Genes involved in Endosomal/Vacuolar pathway |
| 1.4 | 54.5 | REACTOME_INTERFERON_ALPHA_BETA_SIGNALING | Genes involved in Interferon alpha/beta signaling |
| 1.1 | 15.3 | REACTOME_TRAF3_DEPENDENT_IRF_ACTIVATION_PATHWAY | Genes involved in TRAF3-dependent IRF activation pathway |
| 0.4 | 4.9 | REACTOME_AMINE_DERIVED_HORMONES | Genes involved in Amine-derived hormones |
| 0.2 | 1.7 | REACTOME_REGULATION_OF_THE_FANCONI_ANEMIA_PATHWAY | Genes involved in Regulation of the Fanconi anemia pathway |
| 0.2 | 8.3 | REACTOME_SMOOTH_MUSCLE_CONTRACTION | Genes involved in Smooth Muscle Contraction |
| 0.2 | 2.6 | REACTOME_STRIATED_MUSCLE_CONTRACTION | Genes involved in Striated Muscle Contraction |
| 0.2 | 5.6 | REACTOME_INTERFERON_GAMMA_SIGNALING | Genes involved in Interferon gamma signaling |
| 0.2 | 4.2 | REACTOME_TGF_BETA_RECEPTOR_SIGNALING_IN_EMT_EPITHELIAL_TO_MESENCHYMAL_TRANSITION | Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition) |
| 0.2 | 2.2 | REACTOME_EXTRINSIC_PATHWAY_FOR_APOPTOSIS | Genes involved in Extrinsic Pathway for Apoptosis |
| 0.2 | 1.6 | REACTOME_KERATAN_SULFATE_DEGRADATION | Genes involved in Keratan sulfate degradation |
| 0.1 | 1.0 | REACTOME_G2_M_DNA_DAMAGE_CHECKPOINT | Genes involved in G2/M DNA damage checkpoint |
| 0.1 | 0.5 | REACTOME_ACTIVATION_OF_IRF3_IRF7_MEDIATED_BY_TBK1_IKK_EPSILON | Genes involved in Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon |
| 0.1 | 2.0 | REACTOME_UNBLOCKING_OF_NMDA_RECEPTOR_GLUTAMATE_BINDING_AND_ACTIVATION | Genes involved in Unblocking of NMDA receptor, glutamate binding and activation |
| 0.1 | 1.1 | REACTOME_TRYPTOPHAN_CATABOLISM | Genes involved in Tryptophan catabolism |
| 0.1 | 2.6 | REACTOME_HS_GAG_DEGRADATION | Genes involved in HS-GAG degradation |
| 0.1 | 7.2 | REACTOME_COLLAGEN_FORMATION | Genes involved in Collagen formation |
| 0.1 | 2.4 | REACTOME_INHIBITION_OF_THE_PROTEOLYTIC_ACTIVITY_OF_APC_C_REQUIRED_FOR_THE_ONSET_OF_ANAPHASE_BY_MITOTIC_SPINDLE_CHECKPOINT_COMPONENTS | Genes involved in Inhibition of the proteolytic activity of APC/C required for the onset of anaphase by mitotic spindle checkpoint components |
| 0.1 | 0.3 | REACTOME_G_ALPHA1213_SIGNALLING_EVENTS | Genes involved in G alpha (12/13) signalling events |
| 0.1 | 4.6 | REACTOME_BMAL1_CLOCK_NPAS2_ACTIVATES_CIRCADIAN_EXPRESSION | Genes involved in BMAL1:CLOCK/NPAS2 Activates Circadian Expression |
| 0.1 | 2.3 | REACTOME_ACTIVATED_TAK1_MEDIATES_P38_MAPK_ACTIVATION | Genes involved in activated TAK1 mediates p38 MAPK activation |
| 0.1 | 1.0 | REACTOME_DSCAM_INTERACTIONS | Genes involved in DSCAM interactions |
| 0.1 | 6.1 | REACTOME_INTERFERON_SIGNALING | Genes involved in Interferon Signaling |
| 0.1 | 0.6 | REACTOME_THE_ACTIVATION_OF_ARYLSULFATASES | Genes involved in The activation of arylsulfatases |
| 0.1 | 0.9 | REACTOME_REGULATION_OF_RHEB_GTPASE_ACTIVITY_BY_AMPK | Genes involved in Regulation of Rheb GTPase activity by AMPK |
| 0.1 | 2.2 | REACTOME_PIP3_ACTIVATES_AKT_SIGNALING | Genes involved in PIP3 activates AKT signaling |
| 0.1 | 1.7 | REACTOME_GLUTATHIONE_CONJUGATION | Genes involved in Glutathione conjugation |
| 0.1 | 1.0 | REACTOME_SYNTHESIS_OF_SUBSTRATES_IN_N_GLYCAN_BIOSYTHESIS | Genes involved in Synthesis of substrates in N-glycan biosythesis |
| 0.1 | 0.2 | REACTOME_TRAF6_MEDIATED_IRF7_ACTIVATION_IN_TLR7_8_OR_9_SIGNALING | Genes involved in TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling |
| 0.1 | 1.1 | REACTOME_DOWNREGULATION_OF_ERBB2_ERBB3_SIGNALING | Genes involved in Downregulation of ERBB2:ERBB3 signaling |
| 0.1 | 0.4 | REACTOME_PROLACTIN_RECEPTOR_SIGNALING | Genes involved in Prolactin receptor signaling |
| 0.1 | 0.9 | REACTOME_DESTABILIZATION_OF_MRNA_BY_BRF1 | Genes involved in Destabilization of mRNA by Butyrate Response Factor 1 (BRF1) |
| 0.1 | 1.0 | REACTOME_UNWINDING_OF_DNA | Genes involved in Unwinding of DNA |
| 0.1 | 1.0 | REACTOME_IMMUNOREGULATORY_INTERACTIONS_BETWEEN_A_LYMPHOID_AND_A_NON_LYMPHOID_CELL | Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell |
| 0.0 | 1.2 | REACTOME_SYNTHESIS_OF_VERY_LONG_CHAIN_FATTY_ACYL_COAS | Genes involved in Synthesis of very long-chain fatty acyl-CoAs |
| 0.0 | 0.8 | REACTOME_LIGAND_GATED_ION_CHANNEL_TRANSPORT | Genes involved in Ligand-gated ion channel transport |
| 0.0 | 0.9 | REACTOME_CASPASE_MEDIATED_CLEAVAGE_OF_CYTOSKELETAL_PROTEINS | Genes involved in Caspase-mediated cleavage of cytoskeletal proteins |
| 0.0 | 0.5 | REACTOME_TAK1_ACTIVATES_NFKB_BY_PHOSPHORYLATION_AND_ACTIVATION_OF_IKKS_COMPLEX | Genes involved in TAK1 activates NFkB by phosphorylation and activation of IKKs complex |
| 0.0 | 0.8 | REACTOME_IL1_SIGNALING | Genes involved in Interleukin-1 signaling |
| 0.0 | 1.4 | REACTOME_G1_PHASE | Genes involved in G1 Phase |
| 0.0 | 0.6 | REACTOME_EXTENSION_OF_TELOMERES | Genes involved in Extension of Telomeres |
| 0.0 | 0.7 | REACTOME_METABOLISM_OF_PORPHYRINS | Genes involved in Metabolism of porphyrins |
| 0.0 | 0.5 | REACTOME_METABOLISM_OF_STEROID_HORMONES_AND_VITAMINS_A_AND_D | Genes involved in Metabolism of steroid hormones and vitamins A and D |
| 0.0 | 2.0 | REACTOME_MITOTIC_PROMETAPHASE | Genes involved in Mitotic Prometaphase |
| 0.0 | 1.2 | REACTOME_PYRUVATE_METABOLISM_AND_CITRIC_ACID_TCA_CYCLE | Genes involved in Pyruvate metabolism and Citric Acid (TCA) cycle |
| 0.0 | 1.3 | REACTOME_DEPOSITION_OF_NEW_CENPA_CONTAINING_NUCLEOSOMES_AT_THE_CENTROMERE | Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere |
| 0.0 | 0.4 | REACTOME_NUCLEAR_SIGNALING_BY_ERBB4 | Genes involved in Nuclear signaling by ERBB4 |
| 0.0 | 0.5 | REACTOME_DOWNREGULATION_OF_SMAD2_3_SMAD4_TRANSCRIPTIONAL_ACTIVITY | Genes involved in Downregulation of SMAD2/3:SMAD4 transcriptional activity |
| 0.0 | 0.1 | REACTOME_ACYL_CHAIN_REMODELLING_OF_PI | Genes involved in Acyl chain remodelling of PI |
| 0.0 | 0.3 | REACTOME_AMYLOIDS | Genes involved in Amyloids |
| 0.0 | 0.2 | REACTOME_DEADENYLATION_OF_MRNA | Genes involved in Deadenylation of mRNA |
| 0.0 | 0.4 | REACTOME_SEMA4D_IN_SEMAPHORIN_SIGNALING | Genes involved in Sema4D in semaphorin signaling |
| 0.0 | 0.7 | REACTOME_ACTIVATION_OF_CHAPERONE_GENES_BY_XBP1S | Genes involved in Activation of Chaperone Genes by XBP1(S) |
| 0.0 | 0.7 | REACTOME_NETRIN1_SIGNALING | Genes involved in Netrin-1 signaling |
| 0.0 | 0.8 | REACTOME_GLUCOSE_METABOLISM | Genes involved in Glucose metabolism |
| 0.0 | 0.5 | REACTOME_NUCLEAR_RECEPTOR_TRANSCRIPTION_PATHWAY | Genes involved in Nuclear Receptor transcription pathway |
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