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Top targets:

Promoter	Score	Refseq	Gene Symbol	Gene Name
chr7_-_141010759	3.997	ENSMUST00000026565.6	Ifitm3	interferon induced transmembrane protein 3
chr4_-_40239779	3.070	ENSMUST00000037907.6	Ddx58	DEAD (Asp-Glu-Ala-Asp) box polypeptide 58
chr6_-_39118211	2.675	ENSMUST00000038398.6	Parp12	poly (ADP-ribose) polymerase family, member 12
chr17_-_6782775	2.657	ENSMUST00000064234.6	Ezr	ezrin
chr16_+_35938972	2.047	ENSMUST00000023622.6 ENSMUST00000114877.1	Parp9	poly (ADP-ribose) polymerase family, member 9
chr11_+_88999376	1.942	ENSMUST00000100627.2 ENSMUST00000107896.3 ENSMUST00000000284.6	Trim25	tripartite motif-containing 25
chr19_+_55741810	1.853	ENSMUST00000111657.3 ENSMUST00000061496.9 ENSMUST00000041717.7 ENSMUST00000111662.4	Tcf7l2	transcription factor 7 like 2, T cell specific, HMG box
chr2_-_77519565	1.811	ENSMUST00000111830.2	Zfp385b	zinc finger protein 385B
chr4_-_136886187	1.746	ENSMUST00000046384.8	C1qb	complement component 1, q subcomponent, beta polypeptide
chr4_-_40239700	1.555	ENSMUST00000142055.1	Ddx58	DEAD (Asp-Glu-Ala-Asp) box polypeptide 58
chr1_-_163313661	1.216	ENSMUST00000174397.1 ENSMUST00000075805.6 ENSMUST00000027878.7	Prrx1	paired related homeobox 1
chr3_+_138065052	0.954	ENSMUST00000163080.2	1110002E22Rik	RIKEN cDNA 1110002E22 gene
chr15_+_9436028	0.816	ENSMUST00000042360.3	Capsl	calcyphosine-like
chr9_+_45042425	0.801	ENSMUST00000034600.4	Mpzl2	myelin protein zero-like 2
chr16_+_35938470	0.740	ENSMUST00000114878.1	Parp9	poly (ADP-ribose) polymerase family, member 9
chr7_+_128523576	0.694	ENSMUST00000033136.7	Bag3	BCL2-associated athanogene 3
chr7_+_49246131	0.648	ENSMUST00000064395.6	Nav2	neuron navigator 2
chr2_-_77170592	0.561	ENSMUST00000164114.2 ENSMUST00000049544.7	Ccdc141	coiled-coil domain containing 141
chr12_-_31950210	0.542	ENSMUST00000176084.1 ENSMUST00000176103.1 ENSMUST00000167458.2	Hbp1	high mobility group box transcription factor 1
chrX_+_77511002	0.535	ENSMUST00000088217.5	Tbl1x	transducin (beta)-like 1 X-linked
chr9_+_20868628	0.519	ENSMUST00000043911.7	A230050P20Rik	RIKEN cDNA A230050P20 gene
chr12_-_31950170	0.490	ENSMUST00000176520.1	Hbp1	high mobility group box transcription factor 1
chr16_-_67620880	0.489	ENSMUST00000114292.1 ENSMUST00000120898.1	Cadm2	cell adhesion molecule 2
chr16_-_67620805	0.454	ENSMUST00000120594.1	Cadm2	cell adhesion molecule 2
chr16_-_5255923	0.429	ENSMUST00000139584.1 ENSMUST00000064635.5	Fam86	family with sequence similarity 86
chr17_-_78882508	0.406	ENSMUST00000024884.4	Eif2ak2	eukaryotic translation initiation factor 2-alpha kinase 2
chr11_+_72689997	0.358	ENSMUST00000155998.1	Ankfy1	ankyrin repeat and FYVE domain containing 1
chr10_+_80249106	0.325	ENSMUST00000105364.1	Ndufs7	NADH dehydrogenase (ubiquinone) Fe-S protein 7
chr8_-_105568298	0.325	ENSMUST00000005849.5	Agrp	agouti related protein
chr2_-_69586021	0.324	ENSMUST00000100051.2 ENSMUST00000092551.4 ENSMUST00000080953.5	Lrp2	low density lipoprotein receptor-related protein 2
chr10_+_80249441	0.316	ENSMUST00000020361.6	Ndufs7	NADH dehydrogenase (ubiquinone) Fe-S protein 7
chr9_+_55326913	0.316	ENSMUST00000085754.3 ENSMUST00000034862.4	AI118078	expressed sequence AI118078
chr12_-_31950535	0.300	ENSMUST00000172314.2	Hbp1	high mobility group box transcription factor 1
chrM_+_9452	0.292	ENSMUST00000082411.1	mt-Nd3	mitochondrially encoded NADH dehydrogenase 3
chr3_-_142395661	0.272	ENSMUST00000029941.9 ENSMUST00000168967.2 ENSMUST00000090134.5 ENSMUST00000058626.8	Pdlim5	PDZ and LIM domain 5
chrM_+_8600	0.270	ENSMUST00000082409.1	mt-Co3	mitochondrially encoded cytochrome c oxidase III
chr5_+_99979061	0.268	ENSMUST00000046721.1	4930524J08Rik	RIKEN cDNA 4930524J08 gene
chr17_+_34203527	0.250	ENSMUST00000025197.5	Tap2	transporter 2, ATP-binding cassette, sub-family B (MDR/TAP)
chr4_+_108460000	0.250	ENSMUST00000097925.2	Zcchc11	zinc finger, CCHC domain containing 11
chr1_+_52119438	0.241	ENSMUST00000070968.7	Stat1	signal transducer and activator of transcription 1
chr11_-_78984831	0.232	ENSMUST00000073001.4 ENSMUST00000108269.3	Lgals9	lectin, galactose binding, soluble 9
chr2_-_51934644	0.202	ENSMUST00000165313.1	Rbm43	RNA binding motif protein 43
chr9_-_123851855	0.200	ENSMUST00000184082.1 ENSMUST00000167595.2	Fyco1	FYVE and coiled-coil domain containing 1
chr11_+_101582236	0.183	ENSMUST00000039581.7 ENSMUST00000100403.2 ENSMUST00000107194.1 ENSMUST00000128614.1	Tmem106a	transmembrane protein 106A
chr11_-_78984946	0.131	ENSMUST00000108268.3	Lgals9	lectin, galactose binding, soluble 9
chr6_-_87838671	0.125	ENSMUST00000089497.4	Isy1	ISY1 splicing factor homolog (S. cerevisiae)
chr7_-_65370908	0.123	ENSMUST00000032729.6	Tjp1	tight junction protein 1
chr15_+_96287518	0.116	ENSMUST00000134985.2 ENSMUST00000096250.4	Arid2	AT rich interactive domain 2 (ARID, RFX-like)
chr7_-_141266415	0.108	ENSMUST00000106023.1 ENSMUST00000097952.2 ENSMUST00000026571.4	Irf7	interferon regulatory factor 7
chr11_+_69966896	0.098	ENSMUST00000151515.1	Cldn7	claudin 7
chr15_-_76243401	0.084	ENSMUST00000165738.1 ENSMUST00000075689.6	Parp10	poly (ADP-ribose) polymerase family, member 10
chr12_+_26469204	0.076	ENSMUST00000020969.3	Cmpk2	cytidine monophosphate (UMP-CMP) kinase 2, mitochondrial
chr17_+_23679363	0.060	ENSMUST00000024699.2	Cldn6	claudin 6
chr5_-_24447587	0.059	ENSMUST00000127194.1 ENSMUST00000115033.1 ENSMUST00000123167.1 ENSMUST00000030799.8	Tmub1	transmembrane and ubiquitin-like domain containing 1
chr9_-_14381242	0.050	ENSMUST00000167549.1	Endod1	endonuclease domain containing 1
chr3_+_142496924	0.041	ENSMUST00000090127.2	Gbp5	guanylate binding protein 5
chr9_-_123862023	0.041	ENSMUST00000182350.1 ENSMUST00000078755.2	Xcr1	chemokine (C motif) receptor 1
chr11_-_86201144	0.034	ENSMUST00000044423.3	Brip1	BRCA1 interacting protein C-terminal helicase 1
chr1_+_175632169	0.024	ENSMUST00000097458.3	Kmo	kynurenine 3-monooxygenase (kynurenine 3-hydroxylase)
chr16_-_35871544	0.019	ENSMUST00000042665.8	Parp14	poly (ADP-ribose) polymerase family, member 14

Gene overrepresentation in biological_process category:

Log-likelihood per target	Total log-likelihood	Term	Description
1.2	4.6	GO:0009597	detection of virus(GO:0009597)
0.9	2.7	GO:1900041	intestinal D-glucose absorption(GO:0001951) negative regulation of interleukin-2 secretion(GO:1900041) terminal web assembly(GO:1902896)
0.3	5.9	GO:0046597	negative regulation of viral entry into host cell(GO:0046597)
0.3	2.8	GO:0060330	regulation of response to interferon-gamma(GO:0060330)
0.2	1.9	GO:0048625	myoblast fate commitment(GO:0048625)
0.2	0.6	GO:0021564	glossopharyngeal nerve development(GO:0021563) vagus nerve development(GO:0021564)
0.1	1.3	GO:0010745	negative regulation of macrophage derived foam cell differentiation(GO:0010745)
0.1	0.4	GO:1902714	negative regulation of interferon-gamma secretion(GO:1902714)
0.1	1.2	GO:0048664	neuron fate determination(GO:0048664)
0.1	0.3	GO:0002489	antigen processing and presentation of endogenous peptide antigen via MHC class Ib via ER pathway(GO:0002488) antigen processing and presentation of endogenous peptide antigen via MHC class Ib via ER pathway, TAP-dependent(GO:0002489)
0.1	1.7	GO:0006958	complement activation, classical pathway(GO:0006958)
0.1	0.2	GO:0034239	regulation of macrophage fusion(GO:0034239)
0.1	0.4	GO:0032439	endosome localization(GO:0032439) positive regulation of pinocytosis(GO:0048549)
0.0	0.2	GO:1901098	positive regulation of autophagosome maturation(GO:1901098)
0.0	0.4	GO:1900225	NLRP3 inflammasome complex assembly(GO:0044546) regulation of NLRP3 inflammasome complex assembly(GO:1900225)
0.0	0.1	GO:0000389	generation of catalytic spliceosome for second transesterification step(GO:0000350) mRNA 3'-splice site recognition(GO:0000389)
0.0	0.7	GO:0097201	negative regulation of transcription from RNA polymerase II promoter in response to stress(GO:0097201)
0.0	0.3	GO:0008343	adult feeding behavior(GO:0008343)
0.0	0.1	GO:1902915	negative regulation of protein import into nucleus, translocation(GO:0033159) negative regulation of protein K63-linked ubiquitination(GO:1900045) negative regulation of protein polyubiquitination(GO:1902915)
0.0	0.1	GO:0046077	dUDP biosynthetic process(GO:0006227) pyrimidine nucleoside diphosphate metabolic process(GO:0009138) pyrimidine nucleoside diphosphate biosynthetic process(GO:0009139) pyrimidine deoxyribonucleoside diphosphate metabolic process(GO:0009196) pyrimidine deoxyribonucleoside diphosphate biosynthetic process(GO:0009197) dUDP metabolic process(GO:0046077)
0.0	0.3	GO:0044872	lipoprotein transport(GO:0042953) lipoprotein localization(GO:0044872)
0.0	0.6	GO:0034340	response to type I interferon(GO:0034340)
0.0	0.9	GO:0007157	heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0007157)
0.0	1.8	GO:0072332	intrinsic apoptotic signaling pathway by p53 class mediator(GO:0072332)
0.0	0.6	GO:0097031	NADH dehydrogenase complex assembly(GO:0010257) mitochondrial respiratory chain complex I assembly(GO:0032981) mitochondrial respiratory chain complex I biogenesis(GO:0097031)
0.0	0.3	GO:0031054	pre-miRNA processing(GO:0031054) interleukin-6-mediated signaling pathway(GO:0070102)
0.0	0.6	GO:0051642	centrosome localization(GO:0051642)
0.0	0.1	GO:0090557	establishment of endothelial intestinal barrier(GO:0090557)

Gene overrepresentation in cellular_component category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.9	2.7	GO:0098592	cytoplasmic side of apical plasma membrane(GO:0098592)
0.2	1.9	GO:0070369	beta-catenin-TCF7L2 complex(GO:0070369)
0.1	0.3	GO:0005796	Golgi lumen(GO:0005796)
0.1	0.4	GO:0044352	pinosome(GO:0044352) macropinosome(GO:0044354)
0.0	4.6	GO:0032587	ruffle membrane(GO:0032587)
0.0	0.6	GO:0005614	interstitial matrix(GO:0005614)
0.0	0.3	GO:0042825	TAP complex(GO:0042825)
0.0	1.7	GO:0005581	collagen trimer(GO:0005581)
0.0	0.9	GO:0032809	neuronal cell body membrane(GO:0032809)
0.0	0.9	GO:0045271	mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
0.0	0.1	GO:0071012	catalytic step 1 spliceosome(GO:0071012)
0.0	0.1	GO:0046581	intercellular canaliculus(GO:0046581)
0.0	1.8	GO:0001650	fibrillar center(GO:0001650)
0.0	4.0	GO:0045177	apical part of cell(GO:0045177)

Gene overrepresentation in molecular_function category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.3	5.6	GO:0003950	NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.2	2.7	GO:0044548	S100 protein binding(GO:0044548)
0.1	1.9	GO:1904264	ubiquitin protein ligase activity involved in ERAD pathway(GO:1904264)
0.1	0.3	GO:0042954	lipoprotein transporter activity(GO:0042954)
0.1	0.4	GO:0004694	eukaryotic translation initiation factor 2alpha kinase activity(GO:0004694)
0.1	1.9	GO:0070016	gamma-catenin binding(GO:0045295) armadillo repeat domain binding(GO:0070016)
0.1	0.7	GO:0000774	adenyl-nucleotide exchange factor activity(GO:0000774)
0.1	0.3	GO:0015433	peptide antigen-transporting ATPase activity(GO:0015433) tapasin binding(GO:0046980)
0.1	0.4	GO:0016936	galactoside binding(GO:0016936)
0.1	4.6	GO:0003725	double-stranded RNA binding(GO:0003725)
0.1	0.3	GO:0050265	RNA uridylyltransferase activity(GO:0050265)
0.0	0.6	GO:0048038	quinone binding(GO:0048038)
0.0	1.2	GO:0071837	HMG box domain binding(GO:0071837)
0.0	0.2	GO:0031730	CCR5 chemokine receptor binding(GO:0031730)
0.0	0.1	GO:0004127	cytidylate kinase activity(GO:0004127) uridylate kinase activity(GO:0009041)
0.0	1.8	GO:0002039	p53 binding(GO:0002039)
0.0	0.3	GO:0098641	cadherin binding involved in cell-cell adhesion(GO:0098641)
0.0	0.3	GO:0005184	neuropeptide hormone activity(GO:0005184)
0.0	0.1	GO:0071253	connexin binding(GO:0071253)
0.0	0.3	GO:0004129	cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.0	0.3	GO:0050136	NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)

Gene overrepresentation in C2:CP category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	2.7	PID_SYNDECAN_2_PATHWAY	Syndecan-2-mediated signaling events
0.0	1.3	PID_MYC_PATHWAY	C-MYC pathway
0.0	0.2	ST_TYPE_I_INTERFERON_PATHWAY	Type I Interferon (alpha/beta IFN) Pathway
0.0	1.9	PID_AP1_PATHWAY	AP-1 transcription factor network
0.0	0.3	PID_SYNDECAN_3_PATHWAY	Syndecan-3-mediated signaling events
0.0	2.1	NABA_ECM_AFFILIATED	Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.0	0.3	PID_HEDGEHOG_2PATHWAY	Signaling events mediated by the Hedgehog family

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.4	6.7	REACTOME_TRAF3_DEPENDENT_IRF_ACTIVATION_PATHWAY	Genes involved in TRAF3-dependent IRF activation pathway
0.3	1.7	REACTOME_CREATION_OF_C4_AND_C2_ACTIVATORS	Genes involved in Creation of C4 and C2 activators
0.1	4.0	REACTOME_INTERFERON_ALPHA_BETA_SIGNALING	Genes involved in Interferon alpha/beta signaling
0.1	2.7	REACTOME_RECYCLING_PATHWAY_OF_L1	Genes involved in Recycling pathway of L1
0.0	0.1	REACTOME_APOPTOTIC_CLEAVAGE_OF_CELL_ADHESION_PROTEINS	Genes involved in Apoptotic cleavage of cell adhesion proteins
0.0	0.9	REACTOME_ADHERENS_JUNCTIONS_INTERACTIONS	Genes involved in Adherens junctions interactions
0.0	0.3	REACTOME_STEROID_HORMONES	Genes involved in Steroid hormones
0.0	0.5	REACTOME_CIRCADIAN_REPRESSION_OF_EXPRESSION_BY_REV_ERBA	Genes involved in Circadian Repression of Expression by REV-ERBA
0.0	0.3	REACTOME_ANTIGEN_PRESENTATION_FOLDING_ASSEMBLY_AND_PEPTIDE_LOADING_OF_CLASS_I_MHC	Genes involved in Antigen Presentation: Folding, assembly and peptide loading of class I MHC

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