Motif ID: Irx6_Irx2_Irx3
Z-value: 0.608
Transcription factors associated with Irx6_Irx2_Irx3:
Gene Symbol | Entrez ID | Gene Name |
---|---|---|
Irx2 | ENSMUSG00000001504.9 | Irx2 |
Irx3 | ENSMUSG00000031734.11 | Irx3 |
Irx6 | ENSMUSG00000031738.8 | Irx6 |
Activity-expression correlation:
Gene Symbol | Promoter | Pearson corr. coef. | P-value | Plot |
---|---|---|---|---|
Irx2 | mm10_v2_chr13_+_72632597_72632625 | -0.40 | 1.4e-02 | Click! |
Irx6 | mm10_v2_chr8_+_92674826_92674826 | -0.13 | 4.6e-01 | Click! |
Irx3 | mm10_v2_chr8_-_91801948_91802067 | -0.10 | 5.6e-01 | Click! |
Top targets:
Gene overrepresentation in biological_process category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
1.0 | 3.9 | GO:1901475 | pyruvate transmembrane transport(GO:1901475) |
0.7 | 3.5 | GO:0060414 | aorta smooth muscle tissue morphogenesis(GO:0060414) |
0.6 | 3.1 | GO:2000065 | negative regulation of aldosterone metabolic process(GO:0032345) negative regulation of aldosterone biosynthetic process(GO:0032348) negative regulation of cortisol biosynthetic process(GO:2000065) |
0.4 | 1.6 | GO:0086046 | membrane depolarization during SA node cell action potential(GO:0086046) |
0.4 | 1.6 | GO:0048686 | regulation of sprouting of injured axon(GO:0048686) regulation of axon extension involved in regeneration(GO:0048690) |
0.3 | 0.9 | GO:2000659 | regulation of interleukin-1-mediated signaling pathway(GO:2000659) |
0.3 | 1.4 | GO:0072008 | glomerular mesangial cell differentiation(GO:0072008) glomerular mesangial cell development(GO:0072144) |
0.3 | 1.4 | GO:0042636 | negative regulation of hair cycle(GO:0042636) progesterone secretion(GO:0042701) negative regulation of hair follicle development(GO:0051799) positive regulation of ovulation(GO:0060279) |
0.2 | 0.9 | GO:0010808 | positive regulation of synaptic vesicle priming(GO:0010808) |
0.2 | 2.5 | GO:0002098 | tRNA wobble uridine modification(GO:0002098) |
0.2 | 0.6 | GO:1900041 | negative regulation of interleukin-2 secretion(GO:1900041) |
0.2 | 0.5 | GO:0035790 | platelet-derived growth factor receptor-alpha signaling pathway(GO:0035790) |
0.2 | 0.5 | GO:0060785 | regulation of apoptosis involved in tissue homeostasis(GO:0060785) |
0.1 | 0.4 | GO:0043379 | memory T cell differentiation(GO:0043379) |
0.1 | 1.2 | GO:0046085 | adenosine metabolic process(GO:0046085) |
0.1 | 0.7 | GO:1901164 | negative regulation of trophoblast cell migration(GO:1901164) |
0.1 | 0.3 | GO:1904139 | microglial cell migration(GO:1904124) regulation of microglial cell migration(GO:1904139) |
0.1 | 0.4 | GO:0070318 | positive regulation of G0 to G1 transition(GO:0070318) |
0.1 | 0.3 | GO:0032817 | regulation of natural killer cell proliferation(GO:0032817) positive regulation of natural killer cell proliferation(GO:0032819) |
0.1 | 0.5 | GO:0051697 | protein delipidation(GO:0051697) |
0.1 | 0.6 | GO:0045743 | positive regulation of fibroblast growth factor receptor signaling pathway(GO:0045743) |
0.1 | 0.4 | GO:0098735 | cellular response to caffeine(GO:0071313) positive regulation of the force of heart contraction(GO:0098735) |
0.1 | 0.3 | GO:0051771 | negative regulation of nitric-oxide synthase biosynthetic process(GO:0051771) |
0.1 | 0.4 | GO:0002677 | negative regulation of chronic inflammatory response(GO:0002677) |
0.1 | 0.4 | GO:0045039 | protein import into mitochondrial inner membrane(GO:0045039) |
0.1 | 0.2 | GO:2001180 | negative regulation of interleukin-18 production(GO:0032701) negative regulation of interleukin-10 secretion(GO:2001180) |
0.1 | 0.2 | GO:0016561 | protein import into peroxisome matrix, translocation(GO:0016561) |
0.1 | 0.2 | GO:0014809 | regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion(GO:0014809) |
0.1 | 0.2 | GO:0006030 | chitin metabolic process(GO:0006030) chitin catabolic process(GO:0006032) |
0.1 | 0.4 | GO:0042276 | error-prone translesion synthesis(GO:0042276) |
0.1 | 0.7 | GO:0090073 | positive regulation of protein homodimerization activity(GO:0090073) |
0.1 | 0.3 | GO:1900533 | medium-chain fatty-acyl-CoA catabolic process(GO:0036114) long-chain fatty-acyl-CoA catabolic process(GO:0036116) palmitic acid metabolic process(GO:1900533) palmitic acid biosynthetic process(GO:1900535) |
0.1 | 0.7 | GO:0034551 | respiratory chain complex III assembly(GO:0017062) mitochondrial respiratory chain complex III assembly(GO:0034551) mitochondrial respiratory chain complex III biogenesis(GO:0097033) |
0.1 | 0.4 | GO:0006390 | transcription from mitochondrial promoter(GO:0006390) |
0.1 | 1.3 | GO:0006958 | complement activation, classical pathway(GO:0006958) |
0.1 | 0.5 | GO:1900262 | regulation of DNA-directed DNA polymerase activity(GO:1900262) positive regulation of DNA-directed DNA polymerase activity(GO:1900264) |
0.1 | 0.2 | GO:0046022 | regulation of transcription from RNA polymerase II promoter, mitotic(GO:0046021) positive regulation of transcription from RNA polymerase II promoter during mitosis(GO:0046022) |
0.1 | 0.3 | GO:1905150 | regulation of voltage-gated sodium channel activity(GO:1905150) |
0.1 | 0.4 | GO:0010624 | regulation of Schwann cell proliferation(GO:0010624) |
0.1 | 1.0 | GO:0007130 | synaptonemal complex assembly(GO:0007130) |
0.1 | 0.2 | GO:0072488 | ammonium transmembrane transport(GO:0072488) |
0.1 | 2.7 | GO:0034605 | cellular response to heat(GO:0034605) |
0.1 | 1.2 | GO:0070208 | protein heterotrimerization(GO:0070208) |
0.1 | 0.2 | GO:1902938 | regulation of intracellular calcium activated chloride channel activity(GO:1902938) |
0.0 | 0.8 | GO:0006465 | signal peptide processing(GO:0006465) |
0.0 | 0.1 | GO:0051030 | snRNA transport(GO:0051030) |
0.0 | 0.1 | GO:0006507 | GPI anchor release(GO:0006507) |
0.0 | 0.1 | GO:0070543 | response to linoleic acid(GO:0070543) |
0.0 | 0.4 | GO:0000972 | transcription-dependent tethering of RNA polymerase II gene DNA at nuclear periphery(GO:0000972) |
0.0 | 0.3 | GO:0035726 | common myeloid progenitor cell proliferation(GO:0035726) |
0.0 | 0.4 | GO:0006488 | dolichol-linked oligosaccharide biosynthetic process(GO:0006488) |
0.0 | 0.2 | GO:0097343 | ripoptosome assembly(GO:0097343) ripoptosome assembly involved in necroptotic process(GO:1901026) |
0.0 | 0.2 | GO:0042138 | meiotic DNA double-strand break formation(GO:0042138) |
0.0 | 0.2 | GO:0048254 | snoRNA localization(GO:0048254) |
0.0 | 0.2 | GO:1904352 | positive regulation of protein catabolic process in the vacuole(GO:1904352) |
0.0 | 0.4 | GO:0006002 | fructose 6-phosphate metabolic process(GO:0006002) |
0.0 | 0.1 | GO:0006517 | protein deglycosylation(GO:0006517) |
0.0 | 0.3 | GO:1904217 | regulation of CDP-diacylglycerol-serine O-phosphatidyltransferase activity(GO:1904217) positive regulation of CDP-diacylglycerol-serine O-phosphatidyltransferase activity(GO:1904219) regulation of serine C-palmitoyltransferase activity(GO:1904220) positive regulation of serine C-palmitoyltransferase activity(GO:1904222) |
0.0 | 0.1 | GO:0051792 | medium-chain fatty acid biosynthetic process(GO:0051792) |
0.0 | 0.1 | GO:0046368 | GDP-L-fucose metabolic process(GO:0046368) |
0.0 | 0.2 | GO:0002606 | positive regulation of dendritic cell antigen processing and presentation(GO:0002606) detection of bacterium(GO:0016045) detection of other organism(GO:0098543) |
0.0 | 0.2 | GO:0072321 | chaperone-mediated protein transport(GO:0072321) |
0.0 | 0.1 | GO:0070213 | protein auto-ADP-ribosylation(GO:0070213) |
0.0 | 0.4 | GO:0097105 | presynaptic membrane assembly(GO:0097105) |
0.0 | 0.2 | GO:0018230 | peptidyl-L-cysteine S-palmitoylation(GO:0018230) peptidyl-S-diacylglycerol-L-cysteine biosynthetic process from peptidyl-cysteine(GO:0018231) |
0.0 | 0.2 | GO:0006682 | galactosylceramide biosynthetic process(GO:0006682) galactolipid biosynthetic process(GO:0019375) |
0.0 | 0.3 | GO:0070234 | positive regulation of T cell apoptotic process(GO:0070234) |
0.0 | 0.5 | GO:0045793 | positive regulation of cell size(GO:0045793) |
0.0 | 0.3 | GO:0015816 | glycine transport(GO:0015816) |
0.0 | 0.0 | GO:0035456 | response to interferon-beta(GO:0035456) |
0.0 | 0.1 | GO:0034035 | sulfate assimilation(GO:0000103) purine ribonucleoside bisphosphate metabolic process(GO:0034035) 3'-phosphoadenosine 5'-phosphosulfate metabolic process(GO:0050427) |
0.0 | 0.1 | GO:0006106 | fumarate metabolic process(GO:0006106) |
0.0 | 0.2 | GO:1902083 | negative regulation of peptidyl-cysteine S-nitrosylation(GO:1902083) |
0.0 | 0.6 | GO:0046854 | phosphatidylinositol phosphorylation(GO:0046854) |
0.0 | 0.1 | GO:0043983 | histone H4-K12 acetylation(GO:0043983) |
0.0 | 0.3 | GO:0006744 | ubiquinone biosynthetic process(GO:0006744) |
0.0 | 0.1 | GO:0006621 | protein retention in ER lumen(GO:0006621) |
0.0 | 0.1 | GO:0042758 | long-chain fatty acid catabolic process(GO:0042758) |
0.0 | 0.1 | GO:0034975 | protein folding in endoplasmic reticulum(GO:0034975) |
0.0 | 0.1 | GO:0071955 | recycling endosome to Golgi transport(GO:0071955) |
0.0 | 0.2 | GO:0007050 | cell cycle arrest(GO:0007050) |
0.0 | 0.0 | GO:0045204 | MAPK export from nucleus(GO:0045204) |
0.0 | 0.0 | GO:0009794 | regulation of mitotic cell cycle, embryonic(GO:0009794) mitotic cell cycle, embryonic(GO:0045448) |
0.0 | 0.1 | GO:0006122 | mitochondrial electron transport, ubiquinol to cytochrome c(GO:0006122) |
0.0 | 0.2 | GO:0006120 | mitochondrial electron transport, NADH to ubiquinone(GO:0006120) |
0.0 | 0.1 | GO:1901409 | positive regulation of phosphorylation of RNA polymerase II C-terminal domain(GO:1901409) |
0.0 | 0.4 | GO:0035458 | cellular response to interferon-beta(GO:0035458) |
0.0 | 0.3 | GO:0033006 | regulation of mast cell activation involved in immune response(GO:0033006) regulation of mast cell degranulation(GO:0043304) |
0.0 | 0.0 | GO:2001271 | negative regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:2001271) |
0.0 | 0.2 | GO:0045947 | negative regulation of translational initiation(GO:0045947) |
0.0 | 1.0 | GO:0030032 | lamellipodium assembly(GO:0030032) |
0.0 | 0.2 | GO:0034312 | diol biosynthetic process(GO:0034312) |
0.0 | 0.2 | GO:0007194 | negative regulation of adenylate cyclase activity(GO:0007194) |
0.0 | 0.5 | GO:0061003 | positive regulation of dendritic spine morphogenesis(GO:0061003) |
0.0 | 0.2 | GO:0017144 | drug metabolic process(GO:0017144) |
0.0 | 1.0 | GO:0007601 | visual perception(GO:0007601) |
0.0 | 0.5 | GO:0007157 | heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0007157) |
0.0 | 0.3 | GO:0015985 | energy coupled proton transport, down electrochemical gradient(GO:0015985) ATP synthesis coupled proton transport(GO:0015986) |
0.0 | 0.3 | GO:0043171 | peptide catabolic process(GO:0043171) |
0.0 | 0.2 | GO:0097113 | AMPA glutamate receptor clustering(GO:0097113) glutamate receptor clustering(GO:0097688) |
Gene overrepresentation in cellular_component category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.5 | 1.6 | GO:0072534 | perineuronal net(GO:0072534) |
0.5 | 1.4 | GO:0043512 | inhibin A complex(GO:0043512) |
0.3 | 1.4 | GO:0031838 | haptoglobin-hemoglobin complex(GO:0031838) |
0.3 | 1.0 | GO:0000801 | central element(GO:0000801) |
0.3 | 3.5 | GO:0098643 | fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643) |
0.2 | 0.9 | GO:0098831 | presynaptic active zone cytoplasmic component(GO:0098831) |
0.2 | 1.6 | GO:1990454 | L-type voltage-gated calcium channel complex(GO:1990454) |
0.1 | 0.8 | GO:0005787 | signal peptidase complex(GO:0005787) |
0.1 | 0.4 | GO:0097450 | astrocyte end-foot(GO:0097450) |
0.1 | 0.5 | GO:0005663 | DNA replication factor C complex(GO:0005663) |
0.1 | 0.3 | GO:0005965 | protein farnesyltransferase complex(GO:0005965) |
0.1 | 0.4 | GO:0042719 | mitochondrial intermembrane space protein transporter complex(GO:0042719) |
0.1 | 0.4 | GO:0016035 | zeta DNA polymerase complex(GO:0016035) |
0.1 | 1.1 | GO:0005614 | interstitial matrix(GO:0005614) |
0.1 | 0.2 | GO:0034657 | GID complex(GO:0034657) |
0.1 | 0.8 | GO:0031464 | Cul4A-RING E3 ubiquitin ligase complex(GO:0031464) |
0.1 | 0.2 | GO:1990415 | Pex17p-Pex14p docking complex(GO:1990415) peroxisomal importomer complex(GO:1990429) |
0.1 | 1.0 | GO:0097431 | mitotic spindle pole(GO:0097431) |
0.0 | 0.6 | GO:0046930 | pore complex(GO:0046930) |
0.0 | 0.5 | GO:0005687 | U4 snRNP(GO:0005687) |
0.0 | 0.4 | GO:0061574 | ASAP complex(GO:0061574) |
0.0 | 2.0 | GO:0005581 | collagen trimer(GO:0005581) |
0.0 | 0.2 | GO:0031428 | box C/D snoRNP complex(GO:0031428) |
0.0 | 0.1 | GO:0097233 | lamellar body membrane(GO:0097232) alveolar lamellar body membrane(GO:0097233) |
0.0 | 0.2 | GO:0031021 | interphase microtubule organizing center(GO:0031021) |
0.0 | 0.3 | GO:0042571 | immunoglobulin complex, circulating(GO:0042571) |
0.0 | 0.1 | GO:0070985 | TFIIK complex(GO:0070985) |
0.0 | 0.1 | GO:0033186 | CAF-1 complex(GO:0033186) |
0.0 | 0.4 | GO:0042101 | T cell receptor complex(GO:0042101) |
0.0 | 0.2 | GO:0042406 | extrinsic component of endoplasmic reticulum membrane(GO:0042406) |
0.0 | 0.1 | GO:0030690 | Noc1p-Noc2p complex(GO:0030690) |
0.0 | 0.3 | GO:0000276 | mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276) |
0.0 | 0.4 | GO:0002080 | acrosomal membrane(GO:0002080) |
0.0 | 0.2 | GO:0002178 | palmitoyltransferase complex(GO:0002178) |
0.0 | 0.9 | GO:0042645 | nucleoid(GO:0009295) mitochondrial nucleoid(GO:0042645) |
0.0 | 0.1 | GO:0044615 | nuclear pore nuclear basket(GO:0044615) |
0.0 | 0.2 | GO:0097542 | ciliary tip(GO:0097542) |
0.0 | 1.7 | GO:0001725 | stress fiber(GO:0001725) contractile actin filament bundle(GO:0097517) |
0.0 | 0.1 | GO:0000836 | ER ubiquitin ligase complex(GO:0000835) Hrd1p ubiquitin ligase complex(GO:0000836) |
0.0 | 0.3 | GO:0000930 | gamma-tubulin complex(GO:0000930) |
0.0 | 0.1 | GO:0005750 | mitochondrial respiratory chain complex III(GO:0005750) |
0.0 | 0.2 | GO:0016010 | dystrophin-associated glycoprotein complex(GO:0016010) glycoprotein complex(GO:0090665) |
0.0 | 0.3 | GO:0005689 | U12-type spliceosomal complex(GO:0005689) |
0.0 | 0.1 | GO:0005964 | phosphorylase kinase complex(GO:0005964) |
0.0 | 0.1 | GO:0034464 | BBSome(GO:0034464) |
0.0 | 0.2 | GO:0032580 | Golgi cisterna membrane(GO:0032580) |
Gene overrepresentation in molecular_function category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
1.0 | 3.9 | GO:0050833 | pyruvate transmembrane transporter activity(GO:0050833) |
0.4 | 2.5 | GO:0016300 | tRNA (uracil) methyltransferase activity(GO:0016300) |
0.4 | 1.1 | GO:0070052 | collagen V binding(GO:0070052) |
0.3 | 1.4 | GO:0031720 | haptoglobin binding(GO:0031720) |
0.3 | 4.0 | GO:0048407 | platelet-derived growth factor binding(GO:0048407) |
0.2 | 1.4 | GO:0070699 | type II activin receptor binding(GO:0070699) |
0.2 | 1.6 | GO:0086007 | voltage-gated calcium channel activity involved in cardiac muscle cell action potential(GO:0086007) |
0.2 | 0.5 | GO:0004686 | elongation factor-2 kinase activity(GO:0004686) |
0.2 | 1.0 | GO:0019841 | retinol binding(GO:0019841) |
0.2 | 0.5 | GO:0072541 | peroxynitrite reductase activity(GO:0072541) |
0.1 | 0.6 | GO:0004441 | inositol-1,4-bisphosphate 1-phosphatase activity(GO:0004441) |
0.1 | 0.4 | GO:0016160 | alpha-amylase activity(GO:0004556) amylase activity(GO:0016160) |
0.1 | 0.4 | GO:0086038 | calcium:sodium antiporter activity involved in regulation of cardiac muscle cell membrane potential(GO:0086038) |
0.1 | 0.7 | GO:0005094 | Rho GDP-dissociation inhibitor activity(GO:0005094) |
0.1 | 0.4 | GO:0000179 | rRNA (adenine-N6,N6-)-dimethyltransferase activity(GO:0000179) |
0.1 | 1.6 | GO:0046625 | sphingolipid binding(GO:0046625) |
0.1 | 0.3 | GO:0004660 | protein farnesyltransferase activity(GO:0004660) |
0.1 | 0.4 | GO:0019960 | C-X3-C chemokine binding(GO:0019960) |
0.1 | 0.2 | GO:0004492 | methylmalonyl-CoA decarboxylase activity(GO:0004492) |
0.1 | 1.2 | GO:0008253 | 5'-nucleotidase activity(GO:0008253) |
0.1 | 0.5 | GO:0045028 | G-protein coupled nucleotide receptor activity(GO:0001608) G-protein coupled purinergic nucleotide receptor activity(GO:0045028) |
0.1 | 0.3 | GO:0003945 | N-acetyllactosamine synthase activity(GO:0003945) |
0.1 | 0.2 | GO:0004568 | chitinase activity(GO:0004568) |
0.1 | 0.2 | GO:0047275 | glucosaminylgalactosylglucosylceramide beta-galactosyltransferase activity(GO:0047275) |
0.1 | 0.4 | GO:0043199 | sulfate binding(GO:0043199) |
0.1 | 0.3 | GO:1990932 | 5.8S rRNA binding(GO:1990932) |
0.0 | 0.5 | GO:0003689 | DNA clamp loader activity(GO:0003689) protein-DNA loading ATPase activity(GO:0033170) |
0.0 | 0.1 | GO:0070892 | lipoteichoic acid receptor activity(GO:0070892) |
0.0 | 0.1 | GO:0016262 | protein N-acetylglucosaminyltransferase activity(GO:0016262) |
0.0 | 0.2 | GO:0004499 | N,N-dimethylaniline monooxygenase activity(GO:0004499) |
0.0 | 0.2 | GO:1903135 | cupric ion binding(GO:1903135) |
0.0 | 0.7 | GO:0004129 | cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676) |
0.0 | 0.3 | GO:0015187 | glycine transmembrane transporter activity(GO:0015187) |
0.0 | 0.2 | GO:0050700 | CARD domain binding(GO:0050700) |
0.0 | 0.5 | GO:0015269 | calcium-activated potassium channel activity(GO:0015269) |
0.0 | 0.2 | GO:0004301 | epoxide hydrolase activity(GO:0004301) |
0.0 | 0.4 | GO:0008097 | 5S rRNA binding(GO:0008097) |
0.0 | 0.2 | GO:0001094 | TFIID-class transcription factor binding(GO:0001094) |
0.0 | 0.1 | GO:0008534 | oxidized purine nucleobase lesion DNA N-glycosylase activity(GO:0008534) |
0.0 | 0.2 | GO:0061578 | Lys63-specific deubiquitinase activity(GO:0061578) |
0.0 | 0.1 | GO:0004315 | 3-oxoacyl-[acyl-carrier-protein] synthase activity(GO:0004315) |
0.0 | 0.2 | GO:0002162 | dystroglycan binding(GO:0002162) |
0.0 | 0.1 | GO:0015140 | malate transmembrane transporter activity(GO:0015140) |
0.0 | 0.4 | GO:0001848 | complement binding(GO:0001848) |
0.0 | 0.6 | GO:0017134 | fibroblast growth factor binding(GO:0017134) |
0.0 | 0.4 | GO:0008483 | transaminase activity(GO:0008483) |
0.0 | 0.2 | GO:0008395 | steroid hydroxylase activity(GO:0008395) |
0.0 | 0.1 | GO:0004466 | long-chain-acyl-CoA dehydrogenase activity(GO:0004466) |
0.0 | 0.3 | GO:0034987 | immunoglobulin receptor binding(GO:0034987) |
0.0 | 0.1 | GO:0019211 | phosphatase activator activity(GO:0019211) |
0.0 | 0.4 | GO:0005520 | insulin-like growth factor binding(GO:0005520) |
0.0 | 0.3 | GO:0022889 | L-serine transmembrane transporter activity(GO:0015194) serine transmembrane transporter activity(GO:0022889) |
0.0 | 0.4 | GO:0004298 | threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003) |
0.0 | 0.1 | GO:0035877 | death effector domain binding(GO:0035877) |
0.0 | 0.2 | GO:0008190 | eukaryotic initiation factor 4E binding(GO:0008190) |
0.0 | 0.1 | GO:0008121 | ubiquinol-cytochrome-c reductase activity(GO:0008121) oxidoreductase activity, acting on diphenols and related substances as donors(GO:0016679) oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor(GO:0016681) |
0.0 | 0.1 | GO:0015181 | arginine transmembrane transporter activity(GO:0015181) |
0.0 | 0.3 | GO:0070006 | metalloaminopeptidase activity(GO:0070006) |
0.0 | 0.2 | GO:0001618 | virus receptor activity(GO:0001618) |
0.0 | 0.3 | GO:0016290 | palmitoyl-CoA hydrolase activity(GO:0016290) |
0.0 | 0.4 | GO:0003887 | DNA-directed DNA polymerase activity(GO:0003887) |
0.0 | 0.3 | GO:0005104 | fibroblast growth factor receptor binding(GO:0005104) |
0.0 | 0.1 | GO:0031811 | G-protein coupled nucleotide receptor binding(GO:0031811) P2Y1 nucleotide receptor binding(GO:0031812) |
0.0 | 0.2 | GO:0022842 | leak channel activity(GO:0022840) narrow pore channel activity(GO:0022842) |
0.0 | 0.1 | GO:0008479 | queuine tRNA-ribosyltransferase activity(GO:0008479) |
0.0 | 0.8 | GO:0043022 | ribosome binding(GO:0043022) |
0.0 | 0.1 | GO:0004689 | phosphorylase kinase activity(GO:0004689) |
0.0 | 0.6 | GO:0015485 | cholesterol binding(GO:0015485) |
0.0 | 0.1 | GO:0015643 | toxic substance binding(GO:0015643) |
Gene overrepresentation in C2:CP category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.1 | 3.5 | NABA_COLLAGENS | Genes encoding collagen proteins |
0.1 | 3.0 | ST_WNT_BETA_CATENIN_PATHWAY | Wnt/beta-catenin Pathway |
0.0 | 1.4 | PID_ALK1_PATHWAY | ALK1 signaling events |
0.0 | 0.6 | PID_HDAC_CLASSIII_PATHWAY | Signaling events mediated by HDAC Class III |
0.0 | 2.6 | NABA_ECM_GLYCOPROTEINS | Genes encoding structural ECM glycoproteins |
0.0 | 0.3 | PID_ANTHRAX_PATHWAY | Cellular roles of Anthrax toxin |
0.0 | 1.4 | NABA_ECM_AFFILIATED | Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins |
0.0 | 0.2 | PID_P38_GAMMA_DELTA_PATHWAY | Signaling mediated by p38-gamma and p38-delta |
0.0 | 0.5 | PID_ATR_PATHWAY | ATR signaling pathway |
0.0 | 0.3 | PID_PDGFRA_PATHWAY | PDGFR-alpha signaling pathway |
0.0 | 0.7 | PID_CASPASE_PATHWAY | Caspase cascade in apoptosis |
Gene overrepresentation in C2:CP:REACTOME category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.4 | 3.9 | REACTOME_BILE_SALT_AND_ORGANIC_ANION_SLC_TRANSPORTERS | Genes involved in Bile salt and organic anion SLC transporters |
0.3 | 1.4 | REACTOME_GLYCOPROTEIN_HORMONES | Genes involved in Glycoprotein hormones |
0.2 | 1.0 | REACTOME_CREATION_OF_C4_AND_C2_ACTIVATORS | Genes involved in Creation of C4 and C2 activators |
0.1 | 1.2 | REACTOME_PYRIMIDINE_CATABOLISM | Genes involved in Pyrimidine catabolism |
0.1 | 0.9 | REACTOME_ACETYLCHOLINE_NEUROTRANSMITTER_RELEASE_CYCLE | Genes involved in Acetylcholine Neurotransmitter Release Cycle |
0.1 | 0.4 | REACTOME_REGULATION_OF_COMPLEMENT_CASCADE | Genes involved in Regulation of Complement cascade |
0.1 | 3.7 | REACTOME_NCAM1_INTERACTIONS | Genes involved in NCAM1 interactions |
0.1 | 1.7 | REACTOME_DCC_MEDIATED_ATTRACTIVE_SIGNALING | Genes involved in DCC mediated attractive signaling |
0.1 | 0.8 | REACTOME_SYNTHESIS_SECRETION_AND_INACTIVATION_OF_GIP | Genes involved in Synthesis, Secretion, and Inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP) |
0.0 | 0.5 | REACTOME_POL_SWITCHING | Genes involved in Polymerase switching |
0.0 | 0.6 | REACTOME_POST_CHAPERONIN_TUBULIN_FOLDING_PATHWAY | Genes involved in Post-chaperonin tubulin folding pathway |
0.0 | 0.8 | REACTOME_IMMUNOREGULATORY_INTERACTIONS_BETWEEN_A_LYMPHOID_AND_A_NON_LYMPHOID_CELL | Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell |
0.0 | 0.4 | REACTOME_PLATELET_CALCIUM_HOMEOSTASIS | Genes involved in Platelet calcium homeostasis |
0.0 | 0.5 | REACTOME_MTORC1_MEDIATED_SIGNALLING | Genes involved in mTORC1-mediated signalling |
0.0 | 0.8 | REACTOME_BIOSYNTHESIS_OF_THE_N_GLYCAN_PRECURSOR_DOLICHOL_LIPID_LINKED_OLIGOSACCHARIDE_LLO_AND_TRANSFER_TO_A_NASCENT_PROTEIN | Genes involved in Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein |
0.0 | 0.3 | REACTOME_RECRUITMENT_OF_NUMA_TO_MITOTIC_CENTROSOMES | Genes involved in Recruitment of NuMA to mitotic centrosomes |
0.0 | 0.5 | REACTOME_N_GLYCAN_ANTENNAE_ELONGATION_IN_THE_MEDIAL_TRANS_GOLGI | Genes involved in N-glycan antennae elongation in the medial/trans-Golgi |
0.0 | 0.1 | REACTOME_P2Y_RECEPTORS | Genes involved in P2Y receptors |
0.0 | 0.5 | REACTOME_AMINO_ACID_TRANSPORT_ACROSS_THE_PLASMA_MEMBRANE | Genes involved in Amino acid transport across the plasma membrane |
0.0 | 0.2 | REACTOME_CYTOCHROME_P450_ARRANGED_BY_SUBSTRATE_TYPE | Genes involved in Cytochrome P450 - arranged by substrate type |
0.0 | 0.4 | REACTOME_YAP1_AND_WWTR1_TAZ_STIMULATED_GENE_EXPRESSION | Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression |